|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
276-595 |
4.00e-17 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 84.21 E-value: 4.00e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 276 TLLLQDNNMGFYRELYNTSSPQEMVAQFLLVDGNVTNITTVNLWEEFSSSDLSALRFLDMSQNQFRHLPDGFLKKTPSLS 355
Cdd:COG4886 13 LLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 356 HLNLNQNCLKMLHIREHEPPGALTELDLSHNQLAELhlaPGLTGSLRNLRVFNLSSNQLLGVPTGLFdNASSITTIDMSH 435
Cdd:COG4886 93 GDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDL---PEELANLTNLKELDLSNNQLTDLPEPLG-NLTNLKSLDLSN 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 436 NQISLCPQmvpvdwegppscvDFRNMGSLRSLSLDGCGLKALQDCPFQGTSLTHLDLSSNwgvlngSISPLwavaptlqv 515
Cdd:COG4886 169 NQLTDLPE-------------ELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGN------QLTDL--------- 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 516 lslrdvglgsgaaEMDFSAFGNLRALDLSGNSLTSFPKFKGSLALRTLDLRRNSLTALPqrvvSEQPLRGLQTIYLSQNP 595
Cdd:COG4886 221 -------------PEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLP----PLANLTNLKTLDLSNNQ 283
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
106-414 |
4.41e-15 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 78.05 E-value: 4.41e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 106 HLRNLVLADNRLSEnykeSAAALHTLLGLRRLDLSGNSLTEDMAALmlQNLSSLEVVSLARNTLMRLDDSIfEGLEHLVE 185
Cdd:COG4886 114 NLESLDLSGNQLTD----LPEELANLTNLKELDLSNNQLTDLPEPL--GNLTNLKSLDLSNNQLTDLPEEL-GNLTNLKE 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 186 LDLQRNYIFEIeGGAFDGLTELRRLNLAYNN---LPCIVDfSLTQLRFLNVSYNILEWF--LAAREEvafeLEILDLSHN 260
Cdd:COG4886 187 LDLSNNQITDL-PEPLGNLTNLEELDLSGNQltdLPEPLA-NLTNLETLDLSNNQLTDLpeLGNLTN----LEELDLSNN 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 261 QLLFFPLLPQCGKLHTLLLQDNNMGFYRELYNTSSPQEMVAQFLLVDGNVTNITTVNLWEEFSSSDLSALRFLDMSQNQF 340
Cdd:COG4886 261 QLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTL 340
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907117613 341 RHLPDGFLKKTPSLSHLNLNQNCLKMLHIREHEPPGALTELDLSHNQLAELHLAPGLTGSLRNLRVFNLSSNQL 414
Cdd:COG4886 341 ALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
157-217 |
2.63e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 56.38 E-value: 2.63e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907117613 157 SSLEVVSLARNTLMRLDDSIFEGLEHLVELDLQRNYIFEIEGGAFDGLTELRRLNLAYNNL 217
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
60-439 |
3.59e-10 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 63.33 E-value: 3.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 60 RMLILDANPLKDLWNHSLQAYPRLENLSLHSchlDRISHYAFREQGHLRNL---VLADNRLSenyKESAAALHTLLGLRR 136
Cdd:PLN00113 167 KVLDLGGNVLVGKIPNSLTNLTSLEFLTLAS---NQLVGQIPRELGQMKSLkwiYLGYNNLS---GEIPYEIGGLTSLNH 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 137 LDLSGNSLTEDMAAlMLQNLSSLEVVSLARNTLM-RLDDSIFeGLEHLVELDLQRNYIFEIEGGAFDGLTELRRLNLAYN 215
Cdd:PLN00113 241 LDLVYNNLTGPIPS-SLGNLKNLQYLFLYQNKLSgPIPPSIF-SLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSN 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 216 NL----PCIVDfSLTQLRFLNVSYNILEWFLAAREEVAFELEILDLSHN-----------------QLLFF--------- 265
Cdd:PLN00113 319 NFtgkiPVALT-SLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNnltgeipeglcssgnlfKLILFsnslegeip 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 266 PLLPQCGKLHTLLLQDNNmgFYRELYNTSSPQEMVAQFLLVDGNVTNITTVNLWeefsssDLSALRFLDMSQNQFR-HLP 344
Cdd:PLN00113 398 KSLGACRSLRRVRLQDNS--FSGELPSEFTKLPLVYFLDISNNNLQGRINSRKW------DMPSLQMLSLARNKFFgGLP 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 345 DGFlkKTPSLSHLNLNQNCLKMLHIREHEPPGALTELDLSHNQLAelHLAPGLTGSLRNLRVFNLSSNQLLGVPTGLFDN 424
Cdd:PLN00113 470 DSF--GSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLS--GEIPDELSSCKKLVSLDLSHNQLSGQIPASFSE 545
|
410
....*....|....*
gi 1907117613 425 ASSITTIDMSHNQIS 439
Cdd:PLN00113 546 MPVLSQLDLSQNQLS 560
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
137-371 |
9.65e-10 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 59.03 E-value: 9.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 137 LDLSGNSLTEdmaalmLQNLS---SLEVVSLARNTLMRLDDsiFEGLEHLVELDLQRNYIFEIEGgaFDGLTELRRLNLA 213
Cdd:cd21340 7 LYLNDKNITK------IDNLSlckNLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 214 YNNLPCIVDF-SLTQLRFLNVSYNIlewfLAAREEVAFELEILD-LSHNqllffpllpqcgkLHTLLLQDNNMGFYRELY 291
Cdd:cd21340 77 GNRISVVEGLeNLTNLEELHIENQR----LPPGEKLTFDPRSLAaLSNS-------------LRVLNISGNNIDSLEPLA 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 292 NtsspqemvaqfllvdgnvtnittvnlweefsssdLSALRFLDMSQNQFRHLPD--GFLKKTPSLSHLNLNQNCL-KMLH 368
Cdd:cd21340 140 P----------------------------------LRNLEQLDASNNQISDLEEllDLLSSWPSLRELDLTGNPVcKKPK 185
|
...
gi 1907117613 369 IRE 371
Cdd:cd21340 186 YRD 188
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
309-638 |
2.32e-09 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 60.63 E-value: 2.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 309 NVTNITTVNLWEEFSSSDLSALRF-------LDMSQNQFR-HLPDGFLKKTPSLSHLNLNQNCLKMLHIREHEPpgALTE 380
Cdd:PLN00113 67 NSSRVVSIDLSGKNISGKISSAIFrlpyiqtINLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNFTGSIPRGSIP--NLET 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 381 LDLSHNQLA-ELhlaPGLTGSLRNLRVFNLSSNQLLGVPTGLFDNASSITTIDMSHNQISlcpQMVPvdwegppscvdfR 459
Cdd:PLN00113 145 LDLSNNMLSgEI---PNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLV---GQIP------------R 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 460 NMGSLRSLSLDGCGLKALQ-DCPFQ---GTSLTHLDLSSNwgVLNGSISPLWAVAPTLQVLSLRDVGLgSGAAEMDFSAF 535
Cdd:PLN00113 207 ELGQMKSLKWIYLGYNNLSgEIPYEiggLTSLNHLDLVYN--NLTGPIPSSLGNLKNLQYLFLYQNKL-SGPIPPSIFSL 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 536 GNLRALDLSGNSLT-SFPKFKGSL-ALRTLDLRRNSLTALPQRVVSEQPLrgLQTIYLSQNPYDCCGVEGWGalQQHFKT 613
Cdd:PLN00113 284 QKLISLDLSDNSLSgEIPELVIQLqNLEILHLFSNNFTGKIPVALTSLPR--LQVLQLWSNKFSGEIPKNLG--KHNNLT 359
|
330 340
....*....|....*....|....*
gi 1907117613 614 VADLSmvTCNLSSKIvrvvelPEGL 638
Cdd:PLN00113 360 VLDLS--TNNLTGEI------PEGL 376
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
333-564 |
8.35e-07 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 50.55 E-value: 8.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 333 LDMSQNQFRHLPDgfLKKTPSLSHLNLNQNCLKmlHIREHEPPGALTELDLSHNQLAELhlaPGLtGSLRNLRVFNLSSN 412
Cdd:cd21340 7 LYLNDKNITKIDN--LSLCKNLKVLYLYDNKIT--KIENLEFLTNLTHLYLQNNQIEKI---ENL-ENLVNLKKLYLGGN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 413 QLlGVPTGLfDNASSITTIDMSHNQISlcpqmvpvdwEGPPSCVDFRNM----GSLRSLSLDGCGLKALQdcPFQG-TSL 487
Cdd:cd21340 79 RI-SVVEGL-ENLTNLEELHIENQRLP----------PGEKLTFDPRSLaalsNSLRVLNISGNNIDSLE--PLAPlRNL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 488 THLDLSSNwgvlngsisplwavaptlQVLSLRDVglgsgaaEMDFSAFGNLRALDLSGNSLTSFPKFK-----GSLALRT 562
Cdd:cd21340 145 EQLDASNN------------------QISDLEEL-------LDLLSSWPSLRELDLTGNPVCKKPKYRdkiilASKSLEV 199
|
..
gi 1907117613 563 LD 564
Cdd:cd21340 200 LD 201
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
378-438 |
2.28e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.21 E-value: 2.28e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907117613 378 LTELDLSHNQLaeLHLAPGLTGSLRNLRVFNLSSNQLLGVPTGLFDNASSITTIDMSHNQI 438
Cdd:pfam13855 3 LRSLDLSNNRL--TSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
276-595 |
4.00e-17 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 84.21 E-value: 4.00e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 276 TLLLQDNNMGFYRELYNTSSPQEMVAQFLLVDGNVTNITTVNLWEEFSSSDLSALRFLDMSQNQFRHLPDGFLKKTPSLS 355
Cdd:COG4886 13 LLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 356 HLNLNQNCLKMLHIREHEPPGALTELDLSHNQLAELhlaPGLTGSLRNLRVFNLSSNQLLGVPTGLFdNASSITTIDMSH 435
Cdd:COG4886 93 GDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDL---PEELANLTNLKELDLSNNQLTDLPEPLG-NLTNLKSLDLSN 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 436 NQISLCPQmvpvdwegppscvDFRNMGSLRSLSLDGCGLKALQDCPFQGTSLTHLDLSSNwgvlngSISPLwavaptlqv 515
Cdd:COG4886 169 NQLTDLPE-------------ELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGN------QLTDL--------- 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 516 lslrdvglgsgaaEMDFSAFGNLRALDLSGNSLTSFPKFKGSLALRTLDLRRNSLTALPqrvvSEQPLRGLQTIYLSQNP 595
Cdd:COG4886 221 -------------PEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLP----PLANLTNLKTLDLSNNQ 283
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
107-449 |
1.40e-16 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 82.67 E-value: 1.40e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 107 LRNLVLADNRLSENYKESAAALHTLLGLRRLDLSGNSLtedmaalmLQNLSSLEVVSLARNTLMRLDDSIfEGLEHLVEL 186
Cdd:COG4886 71 LLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEE--------LSNLTNLESLDLSGNQLTDLPEEL-ANLTNLKEL 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 187 DLQRNYIFEIeGGAFDGLTELRRLNLAYNNLPCIVDF--SLTQLRFLNVSYN---ILEWFLAAREEvafeLEILDLSHNQ 261
Cdd:COG4886 142 DLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDLPEElgNLTNLKELDLSNNqitDLPEPLGNLTN----LEELDLSGNQ 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 262 LLFFPL-LPQCGKLHTLLLQDNNmgfyrelyntsspqemvaqfllvdgnVTNITTVnlweefssSDLSALRFLDMSQNQF 340
Cdd:COG4886 217 LTDLPEpLANLTNLETLDLSNNQ--------------------------LTDLPEL--------GNLTNLEELDLSNNQL 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 341 RHLPDgfLKKTPSLSHLNLNQNCLKMLHIREHEPPGALTELDLSHNQLAELHLAPGLTGSLRNLRVFNLSSNQLLGVPTG 420
Cdd:COG4886 263 TDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTL 340
|
330 340
....*....|....*....|....*....
gi 1907117613 421 LFDNASSITTIDMSHNQISLCPQMVPVDW 449
Cdd:COG4886 341 ALSLSLLALLTLLLLLNLLSLLLTLLLTL 369
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
210-594 |
5.88e-16 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 80.75 E-value: 5.88e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 210 LNLAYNNLPCIVDFSLTQLRFLNVSYNILEWFLAAREEVAFELEILDLSHNQLLFFPLLPQCGKLHTLLLQDNNMGFYRE 289
Cdd:COG4886 3 LLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 290 LYNTSSPQEMvaqfllvdGNVTNITTVNLWEEFSSSDLSALRFLDMSQNQFRHLPDgflkktpSLSHLNlnqnclkmlhi 369
Cdd:COG4886 83 SLLLLGLTDL--------GDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLPE-------ELANLT----------- 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 370 reheppgALTELDLSHNQLAELhlaPGLTGSLRNLRVFNLSSNQLLGVPTGLfDNASSITTIDMSHNQISlcpqmvpvdw 449
Cdd:COG4886 137 -------NLKELDLSNNQLTDL---PEPLGNLTNLKSLDLSNNQLTDLPEEL-GNLTNLKELDLSNNQIT---------- 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 450 EGPPScvdFRNMGSLRSLSLDGCGLKALQDCPFQGTSLTHLDLSSNwgvlngSISPLwavaPTLQVLSlrdvglgsgaae 529
Cdd:COG4886 196 DLPEP---LGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNN------QLTDL----PELGNLT------------ 250
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907117613 530 mdfsafgNLRALDLSGNSLTSFPKFKGSLALRTLDLRRNSLTALPQRVVSEQPLRGLQTIYLSQN 594
Cdd:COG4886 251 -------NLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLL 308
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
106-414 |
4.41e-15 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 78.05 E-value: 4.41e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 106 HLRNLVLADNRLSEnykeSAAALHTLLGLRRLDLSGNSLTEDMAALmlQNLSSLEVVSLARNTLMRLDDSIfEGLEHLVE 185
Cdd:COG4886 114 NLESLDLSGNQLTD----LPEELANLTNLKELDLSNNQLTDLPEPL--GNLTNLKSLDLSNNQLTDLPEEL-GNLTNLKE 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 186 LDLQRNYIFEIeGGAFDGLTELRRLNLAYNN---LPCIVDfSLTQLRFLNVSYNILEWF--LAAREEvafeLEILDLSHN 260
Cdd:COG4886 187 LDLSNNQITDL-PEPLGNLTNLEELDLSGNQltdLPEPLA-NLTNLETLDLSNNQLTDLpeLGNLTN----LEELDLSNN 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 261 QLLFFPLLPQCGKLHTLLLQDNNMGFYRELYNTSSPQEMVAQFLLVDGNVTNITTVNLWEEFSSSDLSALRFLDMSQNQF 340
Cdd:COG4886 261 QLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTL 340
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907117613 341 RHLPDGFLKKTPSLSHLNLNQNCLKMLHIREHEPPGALTELDLSHNQLAELHLAPGLTGSLRNLRVFNLSSNQL 414
Cdd:COG4886 341 ALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
157-217 |
2.63e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 56.38 E-value: 2.63e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907117613 157 SSLEVVSLARNTLMRLDDSIFEGLEHLVELDLQRNYIFEIEGGAFDGLTELRRLNLAYNNL 217
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
60-439 |
3.59e-10 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 63.33 E-value: 3.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 60 RMLILDANPLKDLWNHSLQAYPRLENLSLHSchlDRISHYAFREQGHLRNL---VLADNRLSenyKESAAALHTLLGLRR 136
Cdd:PLN00113 167 KVLDLGGNVLVGKIPNSLTNLTSLEFLTLAS---NQLVGQIPRELGQMKSLkwiYLGYNNLS---GEIPYEIGGLTSLNH 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 137 LDLSGNSLTEDMAAlMLQNLSSLEVVSLARNTLM-RLDDSIFeGLEHLVELDLQRNYIFEIEGGAFDGLTELRRLNLAYN 215
Cdd:PLN00113 241 LDLVYNNLTGPIPS-SLGNLKNLQYLFLYQNKLSgPIPPSIF-SLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSN 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 216 NL----PCIVDfSLTQLRFLNVSYNILEWFLAAREEVAFELEILDLSHN-----------------QLLFF--------- 265
Cdd:PLN00113 319 NFtgkiPVALT-SLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNnltgeipeglcssgnlfKLILFsnslegeip 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 266 PLLPQCGKLHTLLLQDNNmgFYRELYNTSSPQEMVAQFLLVDGNVTNITTVNLWeefsssDLSALRFLDMSQNQFR-HLP 344
Cdd:PLN00113 398 KSLGACRSLRRVRLQDNS--FSGELPSEFTKLPLVYFLDISNNNLQGRINSRKW------DMPSLQMLSLARNKFFgGLP 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 345 DGFlkKTPSLSHLNLNQNCLKMLHIREHEPPGALTELDLSHNQLAelHLAPGLTGSLRNLRVFNLSSNQLLGVPTGLFDN 424
Cdd:PLN00113 470 DSF--GSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLS--GEIPDELSSCKKLVSLDLSHNQLSGQIPASFSE 545
|
410
....*....|....*
gi 1907117613 425 ASSITTIDMSHNQIS 439
Cdd:PLN00113 546 MPVLSQLDLSQNQLS 560
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
137-371 |
9.65e-10 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 59.03 E-value: 9.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 137 LDLSGNSLTEdmaalmLQNLS---SLEVVSLARNTLMRLDDsiFEGLEHLVELDLQRNYIFEIEGgaFDGLTELRRLNLA 213
Cdd:cd21340 7 LYLNDKNITK------IDNLSlckNLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 214 YNNLPCIVDF-SLTQLRFLNVSYNIlewfLAAREEVAFELEILD-LSHNqllffpllpqcgkLHTLLLQDNNMGFYRELY 291
Cdd:cd21340 77 GNRISVVEGLeNLTNLEELHIENQR----LPPGEKLTFDPRSLAaLSNS-------------LRVLNISGNNIDSLEPLA 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 292 NtsspqemvaqfllvdgnvtnittvnlweefsssdLSALRFLDMSQNQFRHLPD--GFLKKTPSLSHLNLNQNCL-KMLH 368
Cdd:cd21340 140 P----------------------------------LRNLEQLDASNNQISDLEEllDLLSSWPSLRELDLTGNPVcKKPK 185
|
...
gi 1907117613 369 IRE 371
Cdd:cd21340 186 YRD 188
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
309-638 |
2.32e-09 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 60.63 E-value: 2.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 309 NVTNITTVNLWEEFSSSDLSALRF-------LDMSQNQFR-HLPDGFLKKTPSLSHLNLNQNCLKMLHIREHEPpgALTE 380
Cdd:PLN00113 67 NSSRVVSIDLSGKNISGKISSAIFrlpyiqtINLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNFTGSIPRGSIP--NLET 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 381 LDLSHNQLA-ELhlaPGLTGSLRNLRVFNLSSNQLLGVPTGLFDNASSITTIDMSHNQISlcpQMVPvdwegppscvdfR 459
Cdd:PLN00113 145 LDLSNNMLSgEI---PNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLV---GQIP------------R 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 460 NMGSLRSLSLDGCGLKALQ-DCPFQ---GTSLTHLDLSSNwgVLNGSISPLWAVAPTLQVLSLRDVGLgSGAAEMDFSAF 535
Cdd:PLN00113 207 ELGQMKSLKWIYLGYNNLSgEIPYEiggLTSLNHLDLVYN--NLTGPIPSSLGNLKNLQYLFLYQNKL-SGPIPPSIFSL 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 536 GNLRALDLSGNSLT-SFPKFKGSL-ALRTLDLRRNSLTALPQRVVSEQPLrgLQTIYLSQNPYDCCGVEGWGalQQHFKT 613
Cdd:PLN00113 284 QKLISLDLSDNSLSgEIPELVIQLqNLEILHLFSNNFTGKIPVALTSLPR--LQVLQLWSNKFSGEIPKNLG--KHNNLT 359
|
330 340
....*....|....*....|....*
gi 1907117613 614 VADLSmvTCNLSSKIvrvvelPEGL 638
Cdd:PLN00113 360 VLDLS--TNNLTGEI------PEGL 376
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
155-594 |
2.61e-09 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 60.63 E-value: 2.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 155 NLSSLEVVSLA-RNTLMRLDDSIFeGLEHLVELDLQRNYI-FEIEGGAFDGLTELRRLNLAYNNLP-CIVDFSLTQLRFL 231
Cdd:PLN00113 67 NSSRVVSIDLSgKNISGKISSAIF-RLPYIQTINLSNNQLsGPIPDDIFTTSSSLRYLNLSNNNFTgSIPRGSIPNLETL 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 232 NVSYNILEWFLAAREEVAFELEILDLSHNQLL--FFPLLPQCGKLHTLLLQDNNM--GFYREL------------YNTSS 295
Cdd:PLN00113 146 DLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVgkIPNSLTNLTSLEFLTLASNQLvgQIPRELgqmkslkwiylgYNNLS 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 296 ---PQEMVAqflLVDGNVTNITTVNLWEEFSSS--DLSALRFLDMSQNQFR-HLPDGFLKKTPSLShLNLNQNCLKmlhi 369
Cdd:PLN00113 226 geiPYEIGG---LTSLNHLDLVYNNLTGPIPSSlgNLKNLQYLFLYQNKLSgPIPPSIFSLQKLIS-LDLSDNSLS---- 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 370 reheppGALTELDLSHNQLAELHL--------APGLTGSLRNLRVFNLSSNQLLG-VPTGLfDNASSITTIDMSHNQIS- 439
Cdd:PLN00113 298 ------GEIPELVIQLQNLEILHLfsnnftgkIPVALTSLPRLQVLQLWSNKFSGeIPKNL-GKHNNLTVLDLSTNNLTg 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 440 -----LCPQ---------MVPVDWEGPPSCVDFRnmgSLRSLSLDGCGLKALQDCPFQGTSLTH-LDLSSNwgVLNGSIS 504
Cdd:PLN00113 371 eipegLCSSgnlfklilfSNSLEGEIPKSLGACR---SLRRVRLQDNSFSGELPSEFTKLPLVYfLDISNN--NLQGRIN 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 505 PLWAVAPTLQVLSL-RDVGLG---------------------SGAAEMDFSAFGNLRALDLSGNSLTS-FPKFKGSLA-L 560
Cdd:PLN00113 446 SRKWDMPSLQMLSLaRNKFFGglpdsfgskrlenldlsrnqfSGAVPRKLGSLSELMQLKLSENKLSGeIPDELSSCKkL 525
|
490 500 510
....*....|....*....|....*....|....
gi 1907117613 561 RTLDLRRNSLTALPQRVVSEQPLrgLQTIYLSQN 594
Cdd:PLN00113 526 VSLDLSHNQLSGQIPASFSEMPV--LSQLDLSQN 557
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
42-321 |
2.77e-09 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 59.95 E-value: 2.77e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 42 DCRGLNLASVPSSLP--PHSRMLILDANPLKDLwNHSLQAYPRLENLSLHSCHLDRISHyAFREQGHLRNLVLADNRLSE 119
Cdd:COG4886 142 DLSNNQLTDLPEPLGnlTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDLPE-PLGNLTNLEELDLSGNQLTD 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 120 NykesAAALHTLLGLRRLDLSGNSLTEdmaALMLQNLSSLEVVSLARNTLMRLDDSifEGLEHLVELDLQRNYIFEIEGG 199
Cdd:COG4886 220 L----PEPLANLTNLETLDLSNNQLTD---LPELGNLTNLEELDLSNNQLTDLPPL--ANLTNLKTLDLSNNQLTDLKLK 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 200 AFDGLTELRRLNLAYNNLPCIVDFSLTQLrFLNVSYNILEWFLAAREEVAFELEILDLSHNQLLFFPLLPQCGKLHTLLL 279
Cdd:COG4886 291 ELELLLGLNSLLLLLLLLNLLELLILLLL-LTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTL 369
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1907117613 280 QDNNMGFYRELYNTSSPQEMVAQFLLVDGNVTNITTVNLWEE 321
Cdd:COG4886 370 GLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAV 411
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
358-575 |
1.00e-08 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 58.55 E-value: 1.00e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 358 NLNQNCLKMLHIRE--HEPPGALTELDLSHNQLaeLHLAPGLTGSLRNLRVfnlSSNQLLGVPTGLFDN----------- 424
Cdd:PRK15370 179 NKTELRLKILGLTTipACIPEQITTLILDNNEL--KSLPENLQGNIKTLYA---NSNQLTSIPATLPDTiqemelsinri 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 425 -------ASSITTIDMSHNQISLCPQMVPvdwEGppscvdfrnmgsLRSLSLDGCGLKAL-QDCPfqgTSLTHLDLSSNw 496
Cdd:PRK15370 254 telperlPSALQSLDLFHNKISCLPENLP---EE------------LRYLSVYDNSIRTLpAHLP---SGITHLNVQSN- 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 497 gvlngSISPLWAVAP-TLQVLSLRDVGLGSGAAEMDfsafGNLRALDLSGNSLTSFPKfkgSL--ALRTLDLRRNSLTAL 573
Cdd:PRK15370 315 -----SLTALPETLPpGLKTLEAGENALTSLPASLP----PELQVLDVSKNQITVLPE---TLppTITTLDVSRNALTNL 382
|
..
gi 1907117613 574 PQ 575
Cdd:PRK15370 383 PE 384
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
182-236 |
1.35e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.67 E-value: 1.35e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1907117613 182 HLVELDLQRNYIFEIEGGAFDGLTELRRLNLAYNNLPCIVD---FSLTQLRFLNVSYN 236
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPgafSGLPSLRYLDLSGN 59
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
251-446 |
2.94e-07 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 53.93 E-value: 2.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 251 ELEILDLSHNQLLFFPLLPQcGKLHTLLLQDNNMgfyrelynTSSPQEMVAQFLLVDGNVTNITtvnlweEFSSSDLSAL 330
Cdd:PRK15370 200 QITTLILDNNELKSLPENLQ-GNIKTLYANSNQL--------TSIPATLPDTIQEMELSINRIT------ELPERLPSAL 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 331 RFLDMSQNQFRHLPDGFlkkTPSLSHLNLNQNCLKMLhiREHEPPGaLTELDLSHNQLAEL--HLAPGLT---------- 398
Cdd:PRK15370 265 QSLDLFHNKISCLPENL---PEELRYLSVYDNSIRTL--PAHLPSG-ITHLNVQSNSLTALpeTLPPGLKtleagenalt 338
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1907117613 399 ---GSLR-NLRVFNLSSNQLLGVPTGLfdnASSITTIDMSHNQISLCPQMVP 446
Cdd:PRK15370 339 slpASLPpELQVLDVSKNQITVLPETL---PPTITTLDVSRNALTNLPENLP 387
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
333-564 |
8.35e-07 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 50.55 E-value: 8.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 333 LDMSQNQFRHLPDgfLKKTPSLSHLNLNQNCLKmlHIREHEPPGALTELDLSHNQLAELhlaPGLtGSLRNLRVFNLSSN 412
Cdd:cd21340 7 LYLNDKNITKIDN--LSLCKNLKVLYLYDNKIT--KIENLEFLTNLTHLYLQNNQIEKI---ENL-ENLVNLKKLYLGGN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 413 QLlGVPTGLfDNASSITTIDMSHNQISlcpqmvpvdwEGPPSCVDFRNM----GSLRSLSLDGCGLKALQdcPFQG-TSL 487
Cdd:cd21340 79 RI-SVVEGL-ENLTNLEELHIENQRLP----------PGEKLTFDPRSLaalsNSLRVLNISGNNIDSLE--PLAPlRNL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 488 THLDLSSNwgvlngsisplwavaptlQVLSLRDVglgsgaaEMDFSAFGNLRALDLSGNSLTSFPKFK-----GSLALRT 562
Cdd:cd21340 145 EQLDASNN------------------QISDLEEL-------LDLLSSWPSLRELDLTGNPVCKKPKYRdkiilASKSLEV 199
|
..
gi 1907117613 563 LD 564
Cdd:cd21340 200 LD 201
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
18-362 |
1.19e-06 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 52.01 E-value: 1.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 18 EW-RSGPGTATAASQggcKVVDGVADC----------RGLNLASVPSSLPPHSRMLILDANPLKDLwnhslqayPrlENL 86
Cdd:PRK15370 152 EWvKEAPAKEAANRE---EAVQRMRDClknnktelrlKILGLTTIPACIPEQITTLILDNNELKSL--------P--ENL 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 87 slhschldrishyafreQGHLRNLVLADN---RLSENYKESaaalhtllgLRRLDLSGNSLTEdmaalMLQNL-SSLEVV 162
Cdd:PRK15370 219 -----------------QGNIKTLYANSNqltSIPATLPDT---------IQEMELSINRITE-----LPERLpSALQSL 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 163 SLARNTLMRLDDSIFEGLEHlveLDLQRNYIFEIEGGAFDGLTELRRLNLAYNNLPCIVDFSltqLRFLNVSYNILEwfl 242
Cdd:PRK15370 268 DLFHNKISCLPENLPEELRY---LSVYDNSIRTLPAHLPSGITHLNVQSNSLTALPETLPPG---LKTLEAGENALT--- 338
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 243 AAREEVAFELEILDLSHNQLLFFPllpqcgklhtlllqdnnmgfyrelyNTSSPqemVAQFLLVDGNVtnitTVNLWEEF 322
Cdd:PRK15370 339 SLPASLPPELQVLDVSKNQITVLP-------------------------ETLPP---TITTLDVSRNA----LTNLPENL 386
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1907117613 323 SssdlSALRFLDMSQNQFRHLPDG---FLKKTPSLSHLNLNQN 362
Cdd:PRK15370 387 P----AALQIMQASRNNLVRLPESlphFRGEGPQPTRIIVEYN 425
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
357-602 |
1.82e-06 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 50.43 E-value: 1.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 357 LNLNQNCLKMLHIREHEPP-GALTELDLSHNQLAELHlAPGLTGSLR---NLRVFNLSSNQLLGVPTGL------FDNAS 426
Cdd:cd00116 3 LSLKGELLKTERATELLPKlLCLQVLRLEGNTLGEEA-AKALASALRpqpSLKELCLSLNETGRIPRGLqsllqgLTKGC 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 427 SITTIDMSHNqiSLCPqmvpvdwEGPPSCVDFRNMGSLRSLSLDGCGL---------KALQDCPfqgTSLTHLDLSSNwG 497
Cdd:cd00116 82 GLQELDLSDN--ALGP-------DGCGVLESLLRSSSLQELKLNNNGLgdrglrllaKGLKDLP---PALEKLVLGRN-R 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 498 VLNGSISPLWAVAP---TLQVLSLRDVGLGSGAAEM---DFSAFGNLRALDLSGNSLTSF------PKFKGSLALRTLDL 565
Cdd:cd00116 149 LEGASCEALAKALRanrDLKELNLANNGIGDAGIRAlaeGLKANCNLEVLDLNNNGLTDEgasalaETLASLKSLEVLNL 228
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1907117613 566 RRNSLTALPQRVVSEQ---PLRGLQTIYLSQNPYDCCGVE 602
Cdd:cd00116 229 GDNNLTDAGAAALASAllsPNISLLTLSLSCNDITDDGAK 268
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
378-438 |
2.28e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.21 E-value: 2.28e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907117613 378 LTELDLSHNQLaeLHLAPGLTGSLRNLRVFNLSSNQLLGVPTGLFDNASSITTIDMSHNQI 438
Cdd:pfam13855 3 LRSLDLSNNRL--TSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
375-595 |
5.70e-06 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 49.78 E-value: 5.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 375 PGALTELDLSHNQLAELhlaPGLTGSLRNLRVFNLSSNQLLGVPTGLfdnassiTTIDMSHNQISLCPQMVPVDWEgppS 454
Cdd:PRK15387 241 PPELRTLEVSGNQLTSL---PVLPPGLLELSIFSNPLTHLPALPSGL-------CKLWIFGNQLTSLPVLPPGLQE---L 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 455 CVDFRNMGSLRSLSLDGCGLKA----LQDCPFQGTSLTHLDLSSN----WGVLNGSISPLWAVAPTLQVLSlrdvGLGSG 526
Cdd:PRK15387 308 SVSDNQLASLPALPSELCKLWAynnqLTSLPTLPSGLQELSVSDNqlasLPTLPSELYKLWAYNNRLTSLP----ALPSG 383
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 527 AAEMDFSafGN-----------LRALDLSGNSLTSFPKFKGSLAlrTLDLRRNSLTALPQRVVSeqpLRGLQTIYLSQNP 595
Cdd:PRK15387 384 LKELIVS--GNrltslpvlpseLKELMVSGNRLTSLPMLPSGLL--SLSVYRNQLTRLPESLIH---LSSETTVNLEGNP 456
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
133-193 |
1.96e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 42.51 E-value: 1.96e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907117613 133 GLRRLDLSGNSLTeDMAALMLQNLSSLEVVSLARNTLMRLDDSIFEGLEHLVELDLQRNYI 193
Cdd:pfam13855 2 NLRSLDLSNNRLT-SLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
330-388 |
2.65e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 42.13 E-value: 2.65e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1907117613 330 LRFLDMSQNQFRHLPDGFLKKTPSLSHLNLNQNCLKMLHIREHEPPGALTELDLSHNQL 388
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
537-595 |
3.20e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 42.13 E-value: 3.20e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907117613 537 NLRALDLSGNSLTSFPK--FKGSLALRTLDLRRNSLTALPQRVVSeqPLRGLQTIYLSQNP 595
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSPGAFS--GLPSLRYLDLSGNR 60
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
378-574 |
7.55e-05 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 44.39 E-value: 7.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 378 LTELDLSHNQLAELhlapGLTGSLRNLRVFNLSSNQLLGVPTglFDNASSITTIDMSHNQISlcpqmvpvdwegppSCVD 457
Cdd:cd21340 4 ITHLYLNDKNITKI----DNLSLCKNLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIE--------------KIEN 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 458 FRNMGSLRSLSLDG---CGLKALQDCpfqgTSLTHLDLSsnwgvlNGSISP----------LWAVAPTLQVLSLRDVGLG 524
Cdd:cd21340 64 LENLVNLKKLYLGGnriSVVEGLENL----TNLEELHIE------NQRLPPgekltfdprsLAALSNSLRVLNISGNNID 133
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1907117613 525 SGAaemDFSAFGNLRALDLSGNSLTSFPKFKGSLA----LRTLDLRRNSLTALP 574
Cdd:cd21340 134 SLE---PLAPLRNLEQLDASNNQISDLEELLDLLSswpsLRELDLTGNPVCKKP 184
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
369-627 |
9.37e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 45.55 E-value: 9.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 369 IREHEPPGALTELDLShNQLAELHLAPGLTGSLRNLRVFNLSSNQLLGVPTGLFDNasSITTIDMSHNQISLCpqmvpvd 448
Cdd:COG5238 126 TLEDSLILYLALPRRI-NLIQVLKDPLGGNAVHLLGLAARLGLLAAISMAKALQNN--SVETVYLGCNQIGDE------- 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 449 wegppscvdfrnmgslrslsldgcGLKALQDCPFQGTSLTHLDLSSNwgvlngSISPLWAVA--------PTLQVLSLRD 520
Cdd:COG5238 196 ------------------------GIEELAEALTQNTTVTTLWLKRN------PIGDEGAEIlaealkgnKSLTTLDLSN 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 521 VGLGSGAAEMDFSAFGN---LRALDLSGNSLTSfpkfKGSLALRTLdLRRNSltalpqrvvseqplrGLQTIYLSQNPyd 597
Cdd:COG5238 246 NQIGDEGVIALAEALKNnttVETLYLSGNQIGA----EGAIALAKA-LQGNT---------------TLTSLDLSVNR-- 303
|
250 260 270
....*....|....*....|....*....|...
gi 1907117613 598 cCGVEGWGALQQHF---KTVADLSMVTCNLSSK 627
Cdd:COG5238 304 -IGDEGAIALAEGLqgnKTLHTLNLAYNGIGAQ 335
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
402-474 |
1.95e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.82 E-value: 1.95e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907117613 402 RNLRVFNLSSNQLLGVPTGLFDNASSITTIDMSHNQISLcpqmvpVDWEgppscvDFRNMGSLRSLSLDGCGL 474
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT------LSPG------AFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
81-549 |
2.11e-04 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 44.84 E-value: 2.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 81 PRLENLSLHSCHLD-RISHYAFREQGHLRNLVLADNRLSENY-KESAAALHTL------------------LGLRRLDLS 140
Cdd:PLN00113 93 PYIQTINLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNFTGSIpRGSIPNLETLdlsnnmlsgeipndigsfSSLKVLDLG 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 141 GNSLTEDMAAlMLQNLSSLEVVSLARNTL----------MRLDDSIFEGLEHLV-ELDLQrnyifeieggaFDGLTELRR 209
Cdd:PLN00113 173 GNVLVGKIPN-SLTNLTSLEFLTLASNQLvgqiprelgqMKSLKWIYLGYNNLSgEIPYE-----------IGGLTSLNH 240
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 210 LNLAYNNLPCIVDFS---LTQLRFLNVSYNILEWFLAAREEVAFELEILDLSHNQLL--FFPLLPQCGKLHTLLLQDNNM 284
Cdd:PLN00113 241 LDLVYNNLTGPIPSSlgnLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSgeIPELVIQLQNLEILHLFSNNF 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 285 GFYRELYNTSSPQEMVAQfllvdgnvtnittvnLWEEFSSSDLSA-------LRFLDMSQNQFR-HLPDGfLKKTPSLSH 356
Cdd:PLN00113 321 TGKIPVALTSLPRLQVLQ---------------LWSNKFSGEIPKnlgkhnnLTVLDLSTNNLTgEIPEG-LCSSGNLFK 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 357 LNLNQN------------CLKMLHIR------EHEPPGALTEL------DLSHNQLAelhlapGLTGSLR----NLRVFN 408
Cdd:PLN00113 385 LILFSNslegeipkslgaCRSLRRVRlqdnsfSGELPSEFTKLplvyflDISNNNLQ------GRINSRKwdmpSLQMLS 458
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 409 LSSNQLLGVPTGLFdNASSITTIDMSHNQISlcpQMVPVdwegppscvdfrnmgSLRSLSldgcglkalqdcpfqgtSLT 488
Cdd:PLN00113 459 LARNKFFGGLPDSF-GSKRLENLDLSRNQFS---GAVPR---------------KLGSLS-----------------ELM 502
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907117613 489 HLDLSSNwgVLNGSISPLWAVAPTLQVLSLRDVGLgSGAAEMDFSAFGNLRALDLSGNSLT 549
Cdd:PLN00113 503 QLKLSEN--KLSGEIPDELSSCKKLVSLDLSHNQL-SGQIPASFSEMPVLSQLDLSQNQLS 560
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
81-144 |
1.37e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 37.50 E-value: 1.37e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907117613 81 PRLENLSLHSCHLDRISHYAFREQGHLRNLVLADNRLSEnykESAAALHTLLGLRRLDLSGNSL 144
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT---LSPGAFSGLPSLRYLDLSGNRL 61
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
252-549 |
2.01e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 41.31 E-value: 2.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 252 LEILDLSHNQL------LFFPLLPQCGKLHTLLLQDNNMGfyrelyntsspqemvaqfllvdgnvtnittvnlweefsss 325
Cdd:COG5238 182 VETVYLGCNQIgdegieELAEALTQNTTVTTLWLKRNPIG---------------------------------------- 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 326 DLSALRFLDMsqnqfrhlpdgfLKKTPSLSHLNLNQNCLK---MLHIREH-EPPGALTELDLSHNQLAELHLApgltgsl 401
Cdd:COG5238 222 DEGAEILAEA------------LKGNKSLTTLDLSNNQIGdegVIALAEAlKNNTTVETLYLSGNQIGAEGAI------- 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 402 rnlrvfnlssnqllGVPTGLFDNaSSITTIDMSHNQIslcpqmvpvdweGPPSCVDF----RNMGSLRSLSLDGCGL--- 474
Cdd:COG5238 283 --------------ALAKALQGN-TTLTSLDLSVNRI------------GDEGAIALaeglQGNKTLHTLNLAYNGIgaq 335
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 475 ------KALQdcpfQGTSLTHLDLSSNwgvlngSISPLWAVA--------PTLQVLSLRDVGLGS-GAAEM-DFSAFGNL 538
Cdd:COG5238 336 gaialaKALQ----ENTTLHSLDLSDN------QIGDEGAIAlakylegnTTLRELNLGKNNIGKqGAEALiDALQTNRL 405
|
330
....*....|.
gi 1907117613 539 RALDLSGNSLT 549
Cdd:COG5238 406 HTLILDGNLIG 416
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
377-573 |
3.29e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 40.54 E-value: 3.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 377 ALTELDLSHNQLAELH---LAPGLTGSLRnLRVFNLSSNQL--LGVpTGLFD---NASSITTIDMSHNQIslcpqmvpvD 448
Cdd:COG5238 209 TVTTLWLKRNPIGDEGaeiLAEALKGNKS-LTTLDLSNNQIgdEGV-IALAEalkNNTTVETLYLSGNQI---------G 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 449 WEGppscvdfrnmgsLRSLSldgcglKALQDcpfqGTSLTHLDLSSNWGVLNGSIsplwAVAPTLQVLS-LRDVGLGS-- 525
Cdd:COG5238 278 AEG------------AIALA------KALQG----NTTLTSLDLSVNRIGDEGAI----ALAEGLQGNKtLHTLNLAYng 331
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 526 -GAAEMDFSAFG-----NLRALDLSGNSLT-----SFPKF-KGSLALRTLDLRRNSLTAL 573
Cdd:COG5238 332 iGAQGAIALAKAlqentTLHSLDLSDNQIGdegaiALAKYlEGNTTLRELNLGKNNIGKQ 391
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
107-285 |
4.94e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 39.77 E-value: 4.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 107 LRNLVLADNRLSEnykESAAALHTLL----GLRRLDLSGNSLTEDMA---ALMLQNLSSLEVVSLARNtlmRLDDsifEG 179
Cdd:COG5238 238 LTTLDLSNNQIGD---EGVIALAEALknntTVETLYLSGNQIGAEGAialAKALQGNTTLTSLDLSVN---RIGD---EG 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117613 180 LEHLVELdLQRNyifeieggafdglTELRRLNLAYNNLP---CIvdfsltqlrflnvsynilewFLAAREEVAFELEILD 256
Cdd:COG5238 309 AIALAEG-LQGN-------------KTLHTLNLAYNGIGaqgAI--------------------ALAKALQENTTLHSLD 354
|
170 180 190
....*....|....*....|....*....|....*
gi 1907117613 257 LSHNQL------LFFPLLPQCGKLHTLLLQDNNMG 285
Cdd:COG5238 355 LSDNQIgdegaiALAKYLEGNTTLRELNLGKNNIG 389
|
|
| |
