sodium channel protein type 10 subunit alpha isoform X3 [Mus musculus]
Protein Classification
NAD-binding protein; ion transporter; potassium channel family protein; potassium voltage-gated channel protein; potassium voltage-gated channel subfamily KQT member; ion transporter( domain architecture ID 11999107)
NAD-binding protein may be the NAD-binding component of a potassium uptake system similar to Mycobacterium tuberculosis Trk system potassium uptake protein TrkA; ion transporter such as a voltage-gated cation channel, which enables the selective translocation of cations such as sodium, calcium, or potassium, across cell membranes; ion transporter such as a voltage-gated cation channel, which enables the selective translocation of cations such as sodium, calcium, or potassium, across cell membranes; also contains a double zinc ribbon domain; ion transporter such as a voltage-gated cation channel, which enables the selective translocation of cations such as sodium, calcium, or potassium, across cell membranes; contains a double zinc ribbon domain; ion transporter such as a voltage-gated cation channel, which enables the selective translocation of cations such as sodium, calcium, or potassium, across cell membranes; contains a zinc-ribbon domain; potassium channel family protein spans the cell membrane to form a conduction pathway or pore, through which selective ions such as potassium, sodium, and calcium, translocate across cell membranes; potassium voltage-gated channel protein similar to Drosophila melanogaster potassium channels (Shaker, Shaw and Shab), as well as the members from Homo sapiens potassium voltage-gated channel subfamilies (A, C, G, S, and V); potassium voltage-gated channel subfamily KQT member (KCNQ) similar to human KCNQ1, also known as Kv7.1, which is a voltage-dependent K+ channel that regulates gastric acid secretion, salt and glucose homeostasis, and heart rhythm; ion transporter such as a voltage-gated cation channel, which enables the selective translocation of cations such as sodium, calcium, or potassium, across cell membranes
List of domain hits
| Name | Accession | Description | Interval | E-value | |||||
| Na_trans_assoc | pfam06512 | Sodium ion transport-associated; Members of this family contain a region found exclusively in ... |
903-1147 | 1.54e-79 | |||||
Sodium ion transport-associated; Members of this family contain a region found exclusively in eukaryotic sodium channels or their subunits, many of which are voltage-gated. Members very often also contain between one and four copies of pfam00520 and, less often, one copy of pfam00612. : Pssm-ID: 461936 Cd Length: 195 Bit Score: 259.19 E-value: 1.54e-79
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| Ion_trans | pfam00520 | Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
663-893 | 6.67e-63 | |||||
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane. : Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 214.05 E-value: 6.67e-63
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| Ion_trans | pfam00520 | Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
129-406 | 2.92e-56 | |||||
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane. : Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 195.18 E-value: 2.92e-56
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| Name | Accession | Description | Interval | E-value | |||||
| Na_trans_assoc | pfam06512 | Sodium ion transport-associated; Members of this family contain a region found exclusively in ... |
903-1147 | 1.54e-79 | |||||
Sodium ion transport-associated; Members of this family contain a region found exclusively in eukaryotic sodium channels or their subunits, many of which are voltage-gated. Members very often also contain between one and four copies of pfam00520 and, less often, one copy of pfam00612. Pssm-ID: 461936 Cd Length: 195 Bit Score: 259.19 E-value: 1.54e-79
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| Ion_trans | pfam00520 | Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
663-893 | 6.67e-63 | |||||
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane. Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 214.05 E-value: 6.67e-63
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| Ion_trans | pfam00520 | Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
129-406 | 2.92e-56 | |||||
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane. Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 195.18 E-value: 2.92e-56
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| Name | Accession | Description | Interval | E-value | |||||
| Na_trans_assoc | pfam06512 | Sodium ion transport-associated; Members of this family contain a region found exclusively in ... |
903-1147 | 1.54e-79 | |||||
Sodium ion transport-associated; Members of this family contain a region found exclusively in eukaryotic sodium channels or their subunits, many of which are voltage-gated. Members very often also contain between one and four copies of pfam00520 and, less often, one copy of pfam00612. Pssm-ID: 461936 Cd Length: 195 Bit Score: 259.19 E-value: 1.54e-79
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| Ion_trans | pfam00520 | Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
663-893 | 6.67e-63 | |||||
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane. Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 214.05 E-value: 6.67e-63
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| Ion_trans | pfam00520 | Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ... |
129-406 | 2.92e-56 | |||||
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane. Pssm-ID: 459842 [Multi-domain] Cd Length: 238 Bit Score: 195.18 E-value: 2.92e-56
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| PKD_channel | pfam08016 | Polycystin cation channel; This family contains the cation channel region from group II of ... |
702-894 | 1.53e-04 | |||||
Polycystin cation channel; This family contains the cation channel region from group II of Transient receptor potential (TRP) channels, the TRPP subfamily, including PKD1, PKD2, PKD2L and mucolipin proteins. Pssm-ID: 462341 [Multi-domain] Cd Length: 225 Bit Score: 44.57 E-value: 1.53e-04
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