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Conserved domains on  [gi|755493733|ref|XP_011246208|]
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C4b-binding protein isoform X1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 43-299 7.56e-44

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 154.81  E-value: 7.56e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733  43 QMTFTAALWVAVFGKCGPPPAIPNALPASDVNRTDFESH----TTLKYECLPGYgRGISRMMVYCKPSGE-WEISVSCAK 117
Cdd:PHA02927   5 SVTFLTLLGIGCVLSCCTIPSRPINMKFKNSVETDANANynigDTIEYLCLPGY-RKQKMGPIYAKCTGTgWTLFNQCIK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 118 KHCRNPGYLDNGYVNGETITFGSQIEFSCQEGFILVGSSTSSCEVRGKG-VAWSNPFPECVIVKCGPPPDISNGKHSGTE 196
Cdd:PHA02927  84 RRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGSTGsMVWNPEAPICESVKCQSPPSISNGRHNGYE 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 197 DFYPYNHGISYTCDPGFRLVGSPFIGCTVVNktvpvWsSSPPTCEKIICSQPNILHGVIVSGYKATYTHRDSVRLACLNG 276
Cdd:PHA02927 164 DFYTDGSVVTYSCNSGYSLIGNSGVLCSGGE-----W-SDPPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYG 237

                        250       260
                 ....*....|....*....|....
gi 755493733 277 TVLRGRHVIECQGNGNWS-SLPTC 299
Cdd:PHA02927 238 YKLSGSSSSTCSPGNTWQpELPKC 261
C4bp_oligo pfam18453
Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization ...
 416-464 8.80e-24

Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization domain found in C4b-binding protein (C4BP), which contains 14 cysteines that form 7 intermolecular disulfide bridges. C4BP is a plasma glycoprotein complex of 570 kDa, which is mainly produced in the liver. C4BP is the major inhibitor of complement activation, the major isoform consists of 7alpha and one beta-chain where each alpha-chain comprises eight complement control domain proteins (CCPs) and a C-terminal oligomerization domain. This domain carries a stretch of 42-45 amino acids that has been shown to be required for ring formation.


:

Pssm-ID: 436513  Cd Length: 49  Bit Score: 93.66  E-value: 8.80e-24
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 755493733  416 EASEDLKPALTGNKTMQYVPNSHDVKMALEIYKLTLEVELLQLQIQKEK 464
Cdd:pfam18453   1 EFPEGCEQVLTGKKLMQCLPNPEDVKMALEVYKLSLEIELLELQIDKAK 49
PHA02831 super family cl31511
EEV host range protein; Provisional
 290-420 5.05e-16

EEV host range protein; Provisional


The actual alignment was detected with superfamily member PHA02831:

Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 78.11  E-value: 5.05e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 290 NGNWSSLPTC--EFDCDLPPAIVNGYYTSMV--YSKITLVTYECD----KGYRLVGKAIISCSFSKWKGTAPQCKAL-CQ 360
Cdd:PHA02831  63 NGSWSTKNMCigKRNCKDPVTILNGYIKNKKdqYSFGDSVTYACKvnklEKYSIVGNETVKCINKQWVPKYPVCKLIrCK 142

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 361 KPEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRCEQEASED 420
Cdd:PHA02831 143 YPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCVKDKVHN 202
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 43-299 7.56e-44

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 154.81  E-value: 7.56e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733  43 QMTFTAALWVAVFGKCGPPPAIPNALPASDVNRTDFESH----TTLKYECLPGYgRGISRMMVYCKPSGE-WEISVSCAK 117
Cdd:PHA02927   5 SVTFLTLLGIGCVLSCCTIPSRPINMKFKNSVETDANANynigDTIEYLCLPGY-RKQKMGPIYAKCTGTgWTLFNQCIK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 118 KHCRNPGYLDNGYVNGETITFGSQIEFSCQEGFILVGSSTSSCEVRGKG-VAWSNPFPECVIVKCGPPPDISNGKHSGTE 196
Cdd:PHA02927  84 RRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGSTGsMVWNPEAPICESVKCQSPPSISNGRHNGYE 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 197 DFYPYNHGISYTCDPGFRLVGSPFIGCTVVNktvpvWsSSPPTCEKIICSQPNILHGVIVSGYKATYTHRDSVRLACLNG 276
Cdd:PHA02927 164 DFYTDGSVVTYSCNSGYSLIGNSGVLCSGGE-----W-SDPPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYG 237

                        250       260
                 ....*....|....*....|....
gi 755493733 277 TVLRGRHVIECQGNGNWS-SLPTC 299
Cdd:PHA02927 238 YKLSGSSSSTCSPGNTWQpELPKC 261
C4bp_oligo pfam18453
Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization ...
 416-464 8.80e-24

Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization domain found in C4b-binding protein (C4BP), which contains 14 cysteines that form 7 intermolecular disulfide bridges. C4BP is a plasma glycoprotein complex of 570 kDa, which is mainly produced in the liver. C4BP is the major inhibitor of complement activation, the major isoform consists of 7alpha and one beta-chain where each alpha-chain comprises eight complement control domain proteins (CCPs) and a C-terminal oligomerization domain. This domain carries a stretch of 42-45 amino acids that has been shown to be required for ring formation.


Pssm-ID: 436513  Cd Length: 49  Bit Score: 93.66  E-value: 8.80e-24
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 755493733  416 EASEDLKPALTGNKTMQYVPNSHDVKMALEIYKLTLEVELLQLQIQKEK 464
Cdd:pfam18453   1 EFPEGCEQVLTGKKLMQCLPNPEDVKMALEVYKLSLEIELLELQIDKAK 49
PHA02831 PHA02831
EEV host range protein; Provisional
 290-420 5.05e-16

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 78.11  E-value: 5.05e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 290 NGNWSSLPTC--EFDCDLPPAIVNGYYTSMV--YSKITLVTYECD----KGYRLVGKAIISCSFSKWKGTAPQCKAL-CQ 360
Cdd:PHA02831  63 NGSWSTKNMCigKRNCKDPVTILNGYIKNKKdqYSFGDSVTYACKvnklEKYSIVGNETVKCINKQWVPKYPVCKLIrCK 142

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 361 KPEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRCEQEASED 420
Cdd:PHA02831 143 YPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCVKDKVHN 202
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 181-241 3.96e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.94  E-value: 3.96e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755493733 181 CGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCTVVNKtvpvWSSSPPTCE 241
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG----WSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
181-240 4.64e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 57.89  E-value: 4.64e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733  181 CGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCTVVNKtvpvWSSSPPTC 240
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGT----WSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 359-414 1.38e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.70  E-value: 1.38e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 755493733 359 CQKPEV-GNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRCE 414
Cdd:cd00033    1 CPPPPVpENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 181-240 6.52e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 54.84  E-value: 6.52e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733   181 CGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCTvVNKTvpvWSSSPPTC 240
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCL-ENGT---WSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
362-413 3.00e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.89  E-value: 3.00e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 755493733  362 PEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRC 413
Cdd:pfam00084   5 PDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 362-413 2.39e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.22  E-value: 2.39e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 755493733   362 PEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRC 413
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 43-299 7.56e-44

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 154.81  E-value: 7.56e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733  43 QMTFTAALWVAVFGKCGPPPAIPNALPASDVNRTDFESH----TTLKYECLPGYgRGISRMMVYCKPSGE-WEISVSCAK 117
Cdd:PHA02927   5 SVTFLTLLGIGCVLSCCTIPSRPINMKFKNSVETDANANynigDTIEYLCLPGY-RKQKMGPIYAKCTGTgWTLFNQCIK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 118 KHCRNPGYLDNGYVNGETITFGSQIEFSCQEGFILVGSSTSSCEVRGKG-VAWSNPFPECVIVKCGPPPDISNGKHSGTE 196
Cdd:PHA02927  84 RRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGSTGsMVWNPEAPICESVKCQSPPSISNGRHNGYE 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 197 DFYPYNHGISYTCDPGFRLVGSPFIGCTVVNktvpvWsSSPPTCEKIICSQPNILHGVIVSGYKATYTHRDSVRLACLNG 276
Cdd:PHA02927 164 DFYTDGSVVTYSCNSGYSLIGNSGVLCSGGE-----W-SDPPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYG 237

                        250       260
                 ....*....|....*....|....
gi 755493733 277 TVLRGRHVIECQGNGNWS-SLPTC 299
Cdd:PHA02927 238 YKLSGSSSSTCSPGNTWQpELPKC 261
C4bp_oligo pfam18453
Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization ...
 416-464 8.80e-24

Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization domain found in C4b-binding protein (C4BP), which contains 14 cysteines that form 7 intermolecular disulfide bridges. C4BP is a plasma glycoprotein complex of 570 kDa, which is mainly produced in the liver. C4BP is the major inhibitor of complement activation, the major isoform consists of 7alpha and one beta-chain where each alpha-chain comprises eight complement control domain proteins (CCPs) and a C-terminal oligomerization domain. This domain carries a stretch of 42-45 amino acids that has been shown to be required for ring formation.


Pssm-ID: 436513  Cd Length: 49  Bit Score: 93.66  E-value: 8.80e-24
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 755493733  416 EASEDLKPALTGNKTMQYVPNSHDVKMALEIYKLTLEVELLQLQIQKEK 464
Cdd:pfam18453   1 EFPEGCEQVLTGKKLMQCLPNPEDVKMALEVYKLSLEIELLELQIDKAK 49
PHA02639 PHA02639
EEV host range protein; Provisional
 119-299 8.19e-19

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 86.64  E-value: 8.19e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 119 HCRNPGYLDNGYVNG--ETITFGSQIEFSCQEGFILVGSSTSSCEVRGKGVAWSNPFPECVIVKCGPPPDISNGKHSGTE 196
Cdd:PHA02639  21 YCDKPDDISNGFITElmEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFCMLKECNDPPSIINGKIYNKR 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 197 DFYPYNHGISYTCDP----GFRLVGSPFIGCTvVNKTvpvWSSSPPTCEKIICSQPNILHGVI--VSGYKATYtHRDSVR 270
Cdd:PHA02639 101 EMYKVGDEIYYVCNEhkgvQYSLVGNEKITCI-QDKS---WKPDPPICKMINCRFPALQNGYIngIPSNKKFY-YKTRVG 175

                        170       180       190
                 ....*....|....*....|....*....|
gi 755493733 271 LACLNGTVLRGRHVIECQGNGNW-SSLPTC 299
Cdd:PHA02639 176 FSCKSGFDLVGEKYSTCNINATWfPSIPTC 205
PHA02831 PHA02831
EEV host range protein; Provisional
 290-420 5.05e-16

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 78.11  E-value: 5.05e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 290 NGNWSSLPTC--EFDCDLPPAIVNGYYTSMV--YSKITLVTYECD----KGYRLVGKAIISCSFSKWKGTAPQCKAL-CQ 360
Cdd:PHA02831  63 NGSWSTKNMCigKRNCKDPVTILNGYIKNKKdqYSFGDSVTYACKvnklEKYSIVGNETVKCINKQWVPKYPVCKLIrCK 142

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 361 KPEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRCEQEASED 420
Cdd:PHA02831 143 YPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCVKDKVHN 202
PHA02639 PHA02639
EEV host range protein; Provisional
 181-423 1.80e-14

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 73.93  E-value: 1.80e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 181 CGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCtVVNKTVPVWSSSPPTCekiicsqpnilhgvivsgyk 260
Cdd:PHA02639  22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTC-IKDKNNAIWSNKAPFC-------------------- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 261 atythrdsvrlaclngtVLRgrhviecqgngnwsslptcefDCDLPPAIVNG--YYTSMVYSKITLVTYECD--KG--YR 334
Cdd:PHA02639  81 -----------------MLK---------------------ECNDPPSIINGkiYNKREMYKVGDEIYYVCNehKGvqYS 122

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 335 LVGKAIISCSFSK-WKGTAPQCKAL-CQKPEVGNGTLSD--EKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEV 410
Cdd:PHA02639 123 LVGNEKITCIQDKsWKPDPPICKMInCRFPALQNGYINGipSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSI 202

                        250
                 ....*....|....*..
gi 755493733 411 PRCEQEASED----LKP 423
Cdd:PHA02639 203 PTCVRNKPIDdiiyLKP 219
PHA02817 PHA02817
EEV Host range protein; Provisional
 303-413 2.33e-13

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 69.20  E-value: 2.33e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 303 CDLPPAIVNG--YYTSMVYSKITLVTYECDKG-----YRLVGKAIISCSFS-KWKGTAPQCKAL-CQKPEVGNGTLS--- 370
Cdd:PHA02817  24 CCYPPSIKNGyiYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDgKWNKEFPVCKIIrCRFPALQNGFVNgip 103

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 755493733 371 DEKDQYVESEnVTIQCDSGFAMLGSQSISCSESGTWYPEVPRC 413
Cdd:PHA02817 104 DSKKFYYESE-VSFSCKPGFVLIGTKYSVCGINSSWIPKVPIC 145
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 181-241 3.96e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.94  E-value: 3.96e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755493733 181 CGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCTVVNKtvpvWSSSPPTCE 241
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG----WSPPPPTCE 57
PHA02831 PHA02831
EEV host range protein; Provisional
 74-267 4.94e-12

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 66.17  E-value: 4.94e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733  74 NRTdFESHTTLKYEClpgyGRGISRMMVYCKpSGEWEISVSC-AKKHCRNPGYLDNGYVNG--ETITFGSQIEFSCQ--- 147
Cdd:PHA02831  37 NKV-YEENENLEYKC----NNNFDKVFVTCN-NGSWSTKNMCiGKRNCKDPVTILNGYIKNkkDQYSFGDSVTYACKvnk 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 148 -EGFILVGSSTSSCeVRGKgvaWSNPFPECVIVKCGPPPdISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCTVV 226
Cdd:PHA02831 111 lEKYSIVGNETVKC-INKQ---WVPKYPVCKLIRCKYPA-LQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDIN 185

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 755493733 227 NktvpVWSSSPPTCEKiicsqpNILHGVIVSGYKATYTHRD 267
Cdd:PHA02831 186 S----IWYPGIPKCVK------DKVHNEIQPNYLFDDLDED 216
PHA02817 PHA02817
EEV Host range protein; Provisional
 111-256 3.27e-11

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 63.04  E-value: 3.27e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 111 ISVSCAKKHCRNPGYLDNGYV--NGETITFGSQIEFSCQEG-----FILVGSSTSSCEVRGKgvaWSNPFPECVIVKCGP 183
Cdd:PHA02817  15 VYSLCDLNKCCYPPSIKNGYIynKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGK---WNKEFPVCKIIRCRF 91

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755493733 184 PPdISNGKHSGTED---FYpYNHGISYTCDPGFRLVGSPFIGCTvVNKTvpvWSSSPPtcekiICSQPNILHGVIV 256
Cdd:PHA02817  92 PA-LQNGFVNGIPDskkFY-YESEVSFSCKPGFVLIGTKYSVCG-INSS---WIPKVP-----ICSRDNITYNKIY 156
Sushi pfam00084
Sushi repeat (SCR repeat);
181-240 4.64e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 57.89  E-value: 4.64e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733  181 CGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCTVVNKtvpvWSSSPPTC 240
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGT----WSPPFPEC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 185-427 1.02e-10

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 62.80  E-value: 1.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 185 PDISNGKHSGTEDFYPYNHGISYTCDPGFRLVgSPFIGCTVVNktvpvWSSSPPtCEKIiCSQPNILHGVIvsgYKATYT 264
Cdd:PHA02954  24 PTMNNAKLTSTETSFNDKQKVTFTCDSGYYSL-DPNAVCETDK-----WKYENP-CKKM-CTVSDYVSELY---DKPLYE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 265 HRDSVRLACLNGTvlRGRHVIECQGNGNWSSLPTCEFDCDLPPAIVNGYYTSMV--YSKITLVTYECDKGYRLVGKAIIS 342
Cdd:PHA02954  93 VNSTITLICKDET--KYFRCEEKNGNTSWNDTVTCPNAECQPLQLEHGSCQPVKekYSFGEHITINCDVGYEVIGASYIS 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 343 CSFSKWKgTAPQCKALCQKPEVGNGTLSDEKdqYVESENVTIQCDSGFAMLGSQSISCSEsGTWYPEVPRCEQeASEDLK 422
Cdd:PHA02954 171 CTANSWN-VIPSCQQKCDIPSLSNGLISGST--FSIGGVIHLSCKSGFTLTGSPSSTCID-GKWNPVLPICVR-SNEEFD 245


                 ....*
gi 755493733 423 PALTG 427
Cdd:PHA02954 246 PVDDG 250
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 359-414 1.38e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.70  E-value: 1.38e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 755493733 359 CQKPEV-GNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRCE 414
Cdd:cd00033    1 CPPPPVpENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 120-177 5.69e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.78  E-value: 5.69e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 120 CRNPGYLDNGYVNG--ETITFGSQIEFSCQEGFILVGSSTSSCEVRGKgvaWSNPFPECV 177
Cdd:cd00033    1 CPPPPVPENGTVTGskGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG---WSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 181-240 6.52e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 54.84  E-value: 6.52e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733   181 CGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCTvVNKTvpvWSSSPPTC 240
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCL-ENGT---WSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 120-176 1.84e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 53.30  E-value: 1.84e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 755493733   120 CRNPGYLDNGYVNG--ETITFGSQIEFSCQEGFILVGSSTSSCEVRGKgvaWSNPFPEC 176
Cdd:smart00032   1 CPPPPDIENGTVTSssGTYSYGDTVTYSCDPGYTLIGSSTITCLENGT---WSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
362-413 3.00e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.89  E-value: 3.00e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 755493733  362 PEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRC 413
Cdd:pfam00084   5 PDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 303-356 1.08e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 51.31  E-value: 1.08e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 755493733 303 CDLPPAIVNGYYTSM--VYSKITLVTYECDKGYRLVGKAIISCSFS-KWKGTAPQCK 356
Cdd:cd00033    1 CPPPPVPENGTVTGSkgSYSYGSTVTYSCNEGYTLVGSSTITCTENgGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 245-300 1.55e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 50.92  E-value: 1.55e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 755493733 245 CSQPNILHGVIVSGYKATYTHRDSVRLACLNGTVLRGRHVIECQGNGNWS-SLPTCE 300
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 362-413 2.39e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.22  E-value: 2.39e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 755493733   362 PEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRC 413
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 303-355 5.19e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.45  E-value: 5.19e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 755493733   303 CDLPPAIVNGYYTSM--VYSKITLVTYECDKGYRLVGKAIISC-SFSKWKGTAPQC 355
Cdd:smart00032   1 CPPPPDIENGTVTSSsgTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 245-299 1.44e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 47.91  E-value: 1.44e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 755493733   245 CSQPNILHGVIVSGYKATYTHRDSVRLACLNGTVLRGRHVIECQGNGNWS-SLPTC 299
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
120-176 3.50e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.11  E-value: 3.50e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 755493733  120 CRNPGYLDNGYV--NGETITFGSQIEFSCQEGFILVGSSTSSCEVRGKgvaWSNPFPEC 176
Cdd:pfam00084   1 CPPPPDIPNGKVsaTKNEYNYGASVSYECDPGYRLVGSPTITCQEDGT---WSPPFPEC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 359-414 1.45e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 49.17  E-value: 1.45e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755493733 359 CQKPEVGNGTLSDEKDQYVESENVTIQCDSG-----FAMLGSQSISCSESGTWYPEVPRCE 414
Cdd:PHA02817  25 CYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCK 85
Sushi pfam00084
Sushi repeat (SCR repeat);
245-299 1.54e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.18  E-value: 1.54e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 755493733  245 CSQPNILHGVIVSGYKATYTHRDSVRLACLNGTVLRGRHVIECQGNGNWSSL-PTC 299
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPfPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
303-355 4.11e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.03  E-value: 4.11e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 755493733  303 CDLPPAIVNGYYTSM--VYSKITLVTYECDKGYRLVGKAIISCSFS-KWKGTAPQC 355
Cdd:pfam00084   1 CPPPPDIPNGKVSATknEYNYGASVSYECDPGYRLVGSPTITCQEDgTWSPPFPEC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 106-177 9.99e-06

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 47.39  E-value: 9.99e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755493733 106 SGEWEISVSCAKKhCRNPGyLDNGYVNGETITFGSQIEFSCQEGFILVGSSTSSCeVRGKgvaWSNPFPECV 177
Cdd:PHA02954 173 ANSWNVIPSCQQK-CDIPS-LSNGLISGSTFSIGGVIHLSCKSGFTLTGSPSSTC-IDGK---WNPVLPICV 238
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 40-302 1.60e-05

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 46.62  E-value: 1.60e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733  40 TLFQMTFTAALWVAVFGKCGPPPAIPNALPASDvnrTDFESHTTLKYECLPGYGRgiSRMMVYCKpSGEWEISVSCaKKH 119
Cdd:PHA02954   3 TISVVTLLCVLPAVVYSTCTVPTMNNAKLTSTE---TSFNDKQKVTFTCDSGYYS--LDPNAVCE-TDKWKYENPC-KKM 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 120 CRNPGYLDNGYvNGETITFGSQIEFSCQEGfilvgSSTSSCEVRGKGVAWSNPFpECVIVKCgPPPDISNGKHSGTEDFY 199
Cdd:PHA02954  76 CTVSDYVSELY-DKPLYEVNSTITLICKDE-----TKYFRCEEKNGNTSWNDTV-TCPNAEC-QPLQLEHGSCQPVKEKY 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 200 PYNHGISYTCDPGFRLVGSPFIGCTVVNktvpvWSSSPPTCEKiiCSQPNILHGVIvSGykATYTHRDSVRLACLNGTVL 279
Cdd:PHA02954 148 SFGEHITINCDVGYEVIGASYISCTANS-----WNVIPSCQQK--CDIPSLSNGLI-SG--STFSIGGVIHLSCKSGFTL 217

                        250       260
                 ....*....|....*....|....*....
gi 755493733 280 RGRHVIECQgNGNWSS-LPTC-----EFD 302
Cdd:PHA02954 218 TGSPSSTCI-DGKWNPvLPICvrsneEFD 245
PHA02817 PHA02817
EEV Host range protein; Provisional
 57-177 2.30e-05

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 45.70  E-value: 2.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733  57 KCGPPPAIPNALPASdvNRTDFESHTTLKYEClPGYGRGISRMMV-----YCKPSGEWEISVS-CAKKHCRNPGyLDNGY 130
Cdd:PHA02817  23 KCCYPPSIKNGYIYN--KKTEYNIGSNVTFFC-GNNTRGVRYTLVgekniICEKDGKWNKEFPvCKIIRCRFPA-LQNGF 98

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 755493733 131 VNG----ETITFGSQIEFSCQEGFILVGSSTSSCEVRGkgvAWSNPFPECV 177
Cdd:PHA02817  99 VNGipdsKKFYYESEVSFSCKPGFVLIGTKYSVCGINS---SWIPKVPICS 146
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 58-113 5.95e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 37.89  E-value: 5.95e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 755493733    58 CGPPPAIPNALPASDvnRTDFESHTTLKYECLPGYgRGISRMMVYCKPSGEWEISV 113
Cdd:smart00032   1 CPPPPDIENGTVTSS--SGTYSYGDTVTYSCDPGY-TLIGSSTITCLENGTWSPPP 53
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 58-109 1.43e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 36.67  E-value: 1.43e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 755493733  58 CGPPPAIPNALpaSDVNRTDFESHTTLKYECLPGYgRGISRMMVYCKPSGEW 109
Cdd:cd00033    1 CPPPPVPENGT--VTGSKGSYSYGSTVTYSCNEGY-TLVGSSTITCTENGGW 49
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 303-414 3.69e-03

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 39.25  E-value: 3.69e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755493733 303 CDLPPAIVN-------GYYTSMVYSKITLVTYECDKGYRL--VGKAIISCSFSKWKGTAPQCKALCQKP-EVGNGTLSDE 372
Cdd:PHA02927  21 CTIPSRPINmkfknsvETDANANYNIGDTIEYLCLPGYRKqkMGPIYAKCTGTGWTLFNQCIKRRCPSPrDIDNGQLDIG 100

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 755493733 373 KDQYVESenVTIQCDSGFAMLGSQSISCSESGT----WYPEVPRCE 414
Cdd:PHA02927 101 GVDFGSS--ITYSCNSGYQLIGESKSYCELGSTgsmvWNPEAPICE 144
Sushi pfam00084
Sushi repeat (SCR repeat);
58-110 8.26e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 34.78  E-value: 8.26e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 755493733   58 CGPPPAIPNALPASdvNRTDFESHTTLKYECLPGYgRGISRMMVYCKPSGEWE 110
Cdd:pfam00084   1 CPPPPDIPNGKVSA--TKNEYNYGASVSYECDPGY-RLVGSPTITCQEDGTWS 50
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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