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Conserved domains on  [gi|568906203|ref|XP_006495965|]
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KAT8 regulatory NSL complex subunit 3 isoform X1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
COG3571 super family cl43903
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
323-472 2.69e-08

Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];


The actual alignment was detected with superfamily member COG3571:

Pssm-ID: 442792 [Multi-domain]  Cd Length: 202  Bit Score: 54.89  E-value: 2.69e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568906203 323 QCLEHMIGAVRskvlEIHSHFPHKPIILIGWNTGALVACH-VSVMEYVTAVVCLGFPLLTVDGPRGDVDDPLLDMKTPVL 401
Cdd:COG3571   61 VLDAAWRAVIA----ALRARLAGLPLVIGGKSMGGRVASMlAAEGGGAAGLVCLGYPFHPPGKPEKLRTEHLADLTVPTL 136
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568906203 402 FVIGQNSLQCHPEAMEDFRekIRAENSLVVVGGADDNLrisKAKKKSeGLTQSMVDRCIQDEIVDFLTGVL 472
Cdd:COG3571  137 IVQGERDPFGTPEEVAGYP--LPPAIELVWLPGGDHDL---KPRKRS-GRTQEDHLAAAADAVAAWLARLL 201
Nucleoporin_FG2 super family cl37900
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
651-844 8.09e-03

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


The actual alignment was detected with superfamily member pfam15967:

Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 40.04  E-value: 8.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568906203  651 ISQGDTVGGPCTLsqGGTPEAAGGKPITMTLGASAGAKELTGllTTAKSSSSEGGGTASTTPSVASSSATPNaihtlqSR 730
Cdd:pfam15967  10 PGSTATAGGGFSF--GAAAASNPGSTGGFSFGTLGAAPAATA--TTTTATLGLGGGLFGQKPATGFTFGTPA------SS 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568906203  731 LVATSPGSSLPGTASASSLLQ-GLS------------FSLQDISSKTSGLPGSPSPGPAPQATSVklpTPMQ-SLGAITT 796
Cdd:pfam15967  80 TAATGPTGLTLGTPAATTAAStGFSlgfnkpaasatpFSLPASSTSGGGLSLGSVLTSTAAQQGA---TGFTlNLGGTPA 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 568906203  797 GTSTIVRTIPVATTLSSLG-------ATPGGKPTAIHQLLTNGSLAKLASSLPGL 844
Cdd:pfam15967 157 TTTAVSTGLSLGSTLTSLGgslfqntNSTGLGQTTLGLTLLATSTAPVSAPAASE 211
 
Name Accession Description Interval E-value
COG3571 COG3571
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
323-472 2.69e-08

Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];


Pssm-ID: 442792 [Multi-domain]  Cd Length: 202  Bit Score: 54.89  E-value: 2.69e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568906203 323 QCLEHMIGAVRskvlEIHSHFPHKPIILIGWNTGALVACH-VSVMEYVTAVVCLGFPLLTVDGPRGDVDDPLLDMKTPVL 401
Cdd:COG3571   61 VLDAAWRAVIA----ALRARLAGLPLVIGGKSMGGRVASMlAAEGGGAAGLVCLGYPFHPPGKPEKLRTEHLADLTVPTL 136
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568906203 402 FVIGQNSLQCHPEAMEDFRekIRAENSLVVVGGADDNLrisKAKKKSeGLTQSMVDRCIQDEIVDFLTGVL 472
Cdd:COG3571  137 IVQGERDPFGTPEEVAGYP--LPPAIELVWLPGGDHDL---KPRKRS-GRTQEDHLAAAADAVAAWLARLL 201
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
651-844 8.09e-03

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 40.04  E-value: 8.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568906203  651 ISQGDTVGGPCTLsqGGTPEAAGGKPITMTLGASAGAKELTGllTTAKSSSSEGGGTASTTPSVASSSATPNaihtlqSR 730
Cdd:pfam15967  10 PGSTATAGGGFSF--GAAAASNPGSTGGFSFGTLGAAPAATA--TTTTATLGLGGGLFGQKPATGFTFGTPA------SS 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568906203  731 LVATSPGSSLPGTASASSLLQ-GLS------------FSLQDISSKTSGLPGSPSPGPAPQATSVklpTPMQ-SLGAITT 796
Cdd:pfam15967  80 TAATGPTGLTLGTPAATTAAStGFSlgfnkpaasatpFSLPASSTSGGGLSLGSVLTSTAAQQGA---TGFTlNLGGTPA 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 568906203  797 GTSTIVRTIPVATTLSSLG-------ATPGGKPTAIHQLLTNGSLAKLASSLPGL 844
Cdd:pfam15967 157 TTTAVSTGLSLGSTLTSLGgslfqntNSTGLGQTTLGLTLLATSTAPVSAPAASE 211
 
Name Accession Description Interval E-value
COG3571 COG3571
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
323-472 2.69e-08

Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];


Pssm-ID: 442792 [Multi-domain]  Cd Length: 202  Bit Score: 54.89  E-value: 2.69e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568906203 323 QCLEHMIGAVRskvlEIHSHFPHKPIILIGWNTGALVACH-VSVMEYVTAVVCLGFPLLTVDGPRGDVDDPLLDMKTPVL 401
Cdd:COG3571   61 VLDAAWRAVIA----ALRARLAGLPLVIGGKSMGGRVASMlAAEGGGAAGLVCLGYPFHPPGKPEKLRTEHLADLTVPTL 136
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568906203 402 FVIGQNSLQCHPEAMEDFRekIRAENSLVVVGGADDNLrisKAKKKSeGLTQSMVDRCIQDEIVDFLTGVL 472
Cdd:COG3571  137 IVQGERDPFGTPEEVAGYP--LPPAIELVWLPGGDHDL---KPRKRS-GRTQEDHLAAAADAVAAWLARLL 201
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
320-436 2.89e-05

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 46.15  E-value: 2.89e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568906203 320 GVLQCLEHMIGAVRSkVLEIHSHFPHKPIILIGWNTGALVACHVsVMEY---VTAVVCLGfPLLTVDGPRGDVDDPLLDM 396
Cdd:COG2267   74 GHVDSFDDYVDDLRA-ALDALRARPGLPVVLLGHSMGGLIALLY-AARYpdrVAGLVLLA-PAYRADPLLGPSARWLRAL 150
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 568906203 397 ---------KTPVLFVIGQNSLQCHPEAMEDFREKIRAENSLVVVGGAD 436
Cdd:COG2267  151 rlaealariDVPVLVLHGGADRVVPPEAARRLAARLSPDVELVLLPGAR 199
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
651-844 8.09e-03

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 40.04  E-value: 8.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568906203  651 ISQGDTVGGPCTLsqGGTPEAAGGKPITMTLGASAGAKELTGllTTAKSSSSEGGGTASTTPSVASSSATPNaihtlqSR 730
Cdd:pfam15967  10 PGSTATAGGGFSF--GAAAASNPGSTGGFSFGTLGAAPAATA--TTTTATLGLGGGLFGQKPATGFTFGTPA------SS 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568906203  731 LVATSPGSSLPGTASASSLLQ-GLS------------FSLQDISSKTSGLPGSPSPGPAPQATSVklpTPMQ-SLGAITT 796
Cdd:pfam15967  80 TAATGPTGLTLGTPAATTAAStGFSlgfnkpaasatpFSLPASSTSGGGLSLGSVLTSTAAQQGA---TGFTlNLGGTPA 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 568906203  797 GTSTIVRTIPVATTLSSLG-------ATPGGKPTAIHQLLTNGSLAKLASSLPGL 844
Cdd:pfam15967 157 TTTAVSTGLSLGSTLTSLGgslfqntNSTGLGQTTLGLTLLATSTAPVSAPAASE 211
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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