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Conserved domains on  [gi|490736863|ref|WP_004599187|]
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adenylate kinase [Rickettsia prowazekii]

Protein Classification

nucleoside monophosphate kinase( domain architecture ID 11478412)

nucleoside monophosphate kinase catalyzes the transfer of the terminal phosphoryl group from a nucleoside triphosphate, usually ATP, to a nucleoside monophosphate

CATH:  3.40.50.300
EC:  2.7.4.-
Gene Ontology:  GO:0050145|GO:0016310|GO:0046872
PubMed:  2841070
SCOP:  3002021

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
adk PRK00279
adenylate kinase; Reviewed
 1-211 3.17e-98

adenylate kinase; Reviewed


:

Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 283.96  E-value: 3.17e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   1 MIVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNG 80
Cdd:PRK00279   1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  81 YILDGYPRNLEQAKFFEAFIQKPQIKI---IYFDVADELLIKRVLGRYSCKNCGKIYNIHFLQPKIEHVCDVCsSSVFDY 157
Cdd:PRK00279  81 FLLDGFPRTIPQAEALDEMLKELGIKLdavIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVC-GEELIQ 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490736863 158 RKDDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKILK 211
Cdd:PRK00279 160 RADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALG 213
 
Name Accession Description Interval E-value
adk PRK00279
adenylate kinase; Reviewed
 1-211 3.17e-98

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 283.96  E-value: 3.17e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   1 MIVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNG 80
Cdd:PRK00279   1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  81 YILDGYPRNLEQAKFFEAFIQKPQIKI---IYFDVADELLIKRVLGRYSCKNCGKIYNIHFLQPKIEHVCDVCsSSVFDY 157
Cdd:PRK00279  81 FLLDGFPRTIPQAEALDEMLKELGIKLdavIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVC-GEELIQ 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490736863 158 RKDDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKILK 211
Cdd:PRK00279 160 RADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALG 213
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 3-211 1.00e-96

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 280.27  E-value: 1.00e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863    3 VIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKY-KNGY 81
Cdd:TIGR01351   2 LVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDDnENGF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   82 ILDGYPRNLEQAKFFEAFIQKPQIKIIYFDVADELLIKRVLGRYSCKNCGKIYNIHFLQPKiEHVCDVCSSSVFDYRKDD 161
Cdd:TIGR01351  82 ILDGFPRTLSQAEALDALLEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPK-VPGCDDCTGELLVQREDD 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 490736863  162 NKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKILK 211
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNGPIDEVWKRILEALK 210
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 1-210 8.12e-92

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 267.76  E-value: 8.12e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   1 MIVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNG 80
Cdd:COG0563    1 MRIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  81 YILDGYPRNLEQAKFFEAFIQKPQIKI---IYFDVADELLIKRVLGRYSCKNCGKIYNIHFLQPKIEHVCDVCSSSVFdY 157
Cdd:COG0563   81 FILDGFPRTVAQAEALDELLAELGIKLdavIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELV-Q 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490736863 158 RKDDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKIL 210
Cdd:COG0563  160 RADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAIL 212
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 2-202 6.45e-74

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 221.73  E-value: 6.45e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   2 IVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNGY 81
Cdd:cd01428    1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKGF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  82 ILDGYPRNLEQAKFFEAFIQKPQI--KIIYFDVADELLIKRVLGRYSCKNCGKIYNIhflqpkieHVCDVCSSSVFDyRK 159
Cdd:cd01428   81 ILDGFPRTVDQAEALDELLDEGIKpdKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQ-RS 151

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 490736863 160 DDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEI 202
Cdd:cd01428  152 DDNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
ADK pfam00406
Adenylate kinase;
5-186 6.30e-65

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 198.69  E-value: 6.30e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863    5 FLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNGYILD 84
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   85 GYPRNLEQAKFFEAFIQ--KPQIKIIYFDVADELLIKRVLGRYSCKNCGKIYNIHFLQPKIEHVCDVCSSSVFDyRKDDN 162
Cdd:pfam00406  81 GFPRTVPQAEALEELLErgIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQ-RSDDN 159

                         170       180
                  ....*....|....*....|....
gi 490736863  163 KEVIKKRIKVYKTETYPLIDYYKN 186
Cdd:pfam00406 160 EETVKKRLETYHKQTKPLIDYYKK 183
 
Name Accession Description Interval E-value
adk PRK00279
adenylate kinase; Reviewed
 1-211 3.17e-98

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 283.96  E-value: 3.17e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   1 MIVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNG 80
Cdd:PRK00279   1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  81 YILDGYPRNLEQAKFFEAFIQKPQIKI---IYFDVADELLIKRVLGRYSCKNCGKIYNIHFLQPKIEHVCDVCsSSVFDY 157
Cdd:PRK00279  81 FLLDGFPRTIPQAEALDEMLKELGIKLdavIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVC-GEELIQ 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490736863 158 RKDDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKILK 211
Cdd:PRK00279 160 RADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALG 213
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 3-211 1.00e-96

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 280.27  E-value: 1.00e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863    3 VIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKY-KNGY 81
Cdd:TIGR01351   2 LVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDDnENGF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   82 ILDGYPRNLEQAKFFEAFIQKPQIKIIYFDVADELLIKRVLGRYSCKNCGKIYNIHFLQPKiEHVCDVCSSSVFDYRKDD 161
Cdd:TIGR01351  82 ILDGFPRTLSQAEALDALLEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPK-VPGCDDCTGELLVQREDD 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 490736863  162 NKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKILK 211
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNGPIDEVWKRILEALK 210
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 1-210 8.12e-92

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 267.76  E-value: 8.12e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   1 MIVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNG 80
Cdd:COG0563    1 MRIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  81 YILDGYPRNLEQAKFFEAFIQKPQIKI---IYFDVADELLIKRVLGRYSCKNCGKIYNIHFLQPKIEHVCDVCSSSVFdY 157
Cdd:COG0563   81 FILDGFPRTVAQAEALDELLAELGIKLdavIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELV-Q 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490736863 158 RKDDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKIL 210
Cdd:COG0563  160 RADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAIL 212
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 2-202 6.45e-74

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 221.73  E-value: 6.45e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   2 IVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNGY 81
Cdd:cd01428    1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKGF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  82 ILDGYPRNLEQAKFFEAFIQKPQI--KIIYFDVADELLIKRVLGRYSCKNCGKIYNIhflqpkieHVCDVCSSSVFDyRK 159
Cdd:cd01428   81 ILDGFPRTVDQAEALDELLDEGIKpdKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQ-RS 151

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 490736863 160 DDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEI 202
Cdd:cd01428  152 DDNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
ADK pfam00406
Adenylate kinase;
5-186 6.30e-65

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 198.69  E-value: 6.30e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863    5 FLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNGYILD 84
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   85 GYPRNLEQAKFFEAFIQ--KPQIKIIYFDVADELLIKRVLGRYSCKNCGKIYNIHFLQPKIEHVCDVCSSSVFDyRKDDN 162
Cdd:pfam00406  81 GFPRTVPQAEALEELLErgIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQ-RSDDN 159

                         170       180
                  ....*....|....*....|....
gi 490736863  163 KEVIKKRIKVYKTETYPLIDYYKN 186
Cdd:pfam00406 160 EETVKKRLETYHKQTKPLIDYYKK 183
PRK14530 PRK14530
adenylate kinase; Provisional
 3-207 6.00e-52

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 166.50  E-value: 6.00e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   3 VIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRT----IIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSkyk 78
Cdd:PRK14530   6 ILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRAnkqmDISDMDTEYDTPGEYMDAGELVPDAVVNEIVEEALSDA--- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  79 NGYILDGYPRNLEQAKFFEAFIQKPQIkiIYFDVADELLIKRVLGRYSCKNCGKIYNIHFLQPKIEHVCDVCSSSVFDyR 158
Cdd:PRK14530  83 DGFVLDGYPRNLEQAEYLESITDLDVV--LYLDVSEEELVDRLTGRRVCPDCGANYHVEFNQPEEEGVCDECGGELIQ-R 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 490736863 159 KDDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQ 207
Cdd:PRK14530 160 DDDTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTPDEVWADIQ 208
adk PRK02496
adenylate kinase; Provisional
 3-211 2.06e-50

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 161.84  E-value: 2.06e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   3 VIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNGYI 82
Cdd:PRK02496   4 LIFLGPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQERLQQPDAANGWI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  83 LDGYPRNLEQAKFFEAFIQK---PQIKIIYFDVADELLIKRVLGRysckncgkiynihflqpkiehvcdvcsssvfdYRK 159
Cdd:PRK02496  84 LDGFPRKVTQAAFLDELLQEigqSGERVVNLDVPDDVVVERLLAR--------------------------------GRK 131

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 490736863 160 DDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKILK 211
Cdd:PRK02496 132 DDTEEVIRRRLEVYREQTAPLIDYYRDRQKLLTIDGNQSVEAVTTELKAALA 183
PRK14526 PRK14526
adenylate kinase; Provisional
 1-210 2.04e-49

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 160.02  E-value: 2.04e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   1 MIVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNG 80
Cdd:PRK14526   1 MKLVFLGPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVEDKINTIKNNDN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  81 YILDGYPRNLEQAKFFEAFIqkPQIKIIYFDVADELLIKRVLGRYSCKNCGKIYNIHFLQPKIEHVCDVCSSSVFDyRKD 160
Cdd:PRK14526  81 FILDGFPRNINQAKALDKFL--PNIKIINFLIDEELLIKRLSGRRICKSCNNIFNIYTLPTKEKGICDVCKGDLYQ-RKD 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 490736863 161 DNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKIL 210
Cdd:PRK14526 158 DKEESLKTRLQEYKLQTKPLIEFYSKCNRLNNIDASKDIDEVKKKLIEII 207
PRK14528 PRK14528
adenylate kinase; Provisional
 3-210 1.93e-43

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 144.00  E-value: 1.93e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   3 VIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNGYI 82
Cdd:PRK14528   4 IIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKDRIREADCKNGFL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  83 LDGYPRNLEQAKFFEAFIQKPQI---KIIYFDVADELLIKRVLGRysckncgkiynihflqpkiehvcdvcssSVFDYRK 159
Cdd:PRK14528  84 LDGFPRTVEQADALDALLKNEGKsidKAINLEVPDGELLKRLLGR----------------------------AEIEGRA 135

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 490736863 160 DDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKIL 210
Cdd:PRK14528 136 DDNEATIKNRLDNYNKKTLPLLDFYAAQKKLSQVNGVGSLEEVTSLIQKEL 186
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 3-211 2.75e-39

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 133.27  E-value: 2.75e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863    3 VIF-LGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSE-AELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNG 80
Cdd:TIGR01359   1 VVFvLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIKREGSEnGSLIESYIKEGKIVPSEVTVELLKKAIQEDGSSKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   81 YILDGYPRNLEQAKFFEAFI-QKPQIK-IIYFDVADELLIKRVLGRysckncgkiynihflqpkiehvcdvcssSVFDYR 158
Cdd:TIGR01359  81 FLIDGFPRNEENLEAWEKLMdNKVNFKfVLFFDCPEETMIKRLLKR----------------------------GQTSGR 132

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 490736863  159 KDDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKILK 211
Cdd:TIGR01359 133 VDDNIETLKKRFRTYNEETLPIIEHFENKGKVKEINAEGSVEEVFEDVEKIFA 185
PLN02674 PLN02674
adenylate kinase
 3-210 5.73e-39

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 134.24  E-value: 5.73e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   3 VIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNGYI 82
Cdd:PLN02674  34 LILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIIDEAMKKPSCQKGFI 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  83 LDGYPRNLEQAKFFEAFIQKPQIKI---IYFDVADELLIKRVLGRYSCKNCGKIYNIHFLQPKIEHVCDVCSSSVFDyRK 159
Cdd:PLN02674 114 LDGFPRTVVQAQKLDEMLAKQGAKIdkvLNFAIDDAILEERITGRWIHPSSGRTYHTKFAPPKVPGVDDVTGEPLIQ-RK 192

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 490736863 160 DDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKIL 210
Cdd:PLN02674 193 DDTAAVLKSRLEAFHKQTEPVIDYYAKKGVVANLHAEKPPKEVTAEVQKAL 243
PLN02459 PLN02459
probable adenylate kinase
 4-188 3.32e-37

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 130.35  E-value: 3.32e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   4 IFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIK--VFLLSSKYKNGY 81
Cdd:PLN02459  33 VFLGCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLSkrLEAGEEEGESGF 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  82 ILDGYPRNLEQAKFFEAFIQKPQikIIYFDVADELLIKRVLGRYSCKNCGKIYNIHFLQPKIE--------------HVC 147
Cdd:PLN02459 113 ILDGFPRTVRQAEILEGVTDIDL--VVNLKLREEVLVEKCLGRRICSECGKNFNVADIDLKGEdgrpgivmppllppPEC 190

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 490736863 148 dvcsSSVFDYRKDDNKEVIKKRIKVYKTETYPLIDYYKNSG 188
Cdd:PLN02459 191 ----ASKLITRADDTEEVVKARLRVYKEESQPVEDFYRKRG 227
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 2-202 8.33e-37

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 126.85  E-value: 8.33e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863    2 IVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKN-G 80
Cdd:TIGR01360   5 IIFIVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAMVAALGTSkG 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   81 YILDGYPRNLEQAKFFEAFIQKPQIkIIYFDVADELLIKRVLGRysckncgkiynihflqpkiehvcdvCSSSVfdyRKD 160
Cdd:TIGR01360  85 FLIDGYPREVKQGEEFERRIGPPTL-VLYFDCSEDTMVKRLLKR-------------------------AETSG---RVD 135

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 490736863  161 DNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEI 202
Cdd:TIGR01360 136 DNEKTIKKRLETYYKATEPVIAYYETKGKLRKINAEGTVDDV 177
PRK14531 PRK14531
adenylate kinase; Provisional
 3-210 3.11e-34

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 120.30  E-value: 3.11e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   3 VIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTS---EAELINNyvkQGALIPNEIVNQVIKVfLLSSKYKN 79
Cdd:PRK14531   5 LLFLGPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSAlgqEAEAVMN---RGELVSDALVLAIVES-QLKALNSG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  80 GYILDGYPRNLEQAKFFEAF---IQKPQIKIIYFDVADELLIKRVLGRysckncgkiynihflqpkiehvcdvcsssvfd 156
Cdd:PRK14531  81 GWLLDGFPRTVAQAEALEPLleeLKQPIEAVVLLELDDAVLIERLLAR-------------------------------- 128

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490736863 157 YRKDDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKIL 210
Cdd:PRK14531 129 GRADDNEAVIRNRLEVYREKTAPLIDHYRQRGLLQSVEAQGSIEAITERIEKVL 182
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 1-188 3.57e-34

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 121.44  E-value: 3.57e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   1 MIVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFL--LSSKYK 78
Cdd:PTZ00088   7 LKIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIVKDEIakVTDDCF 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  79 NGYILDGYPRNLEQAKFFEAFIQKPQIKIIYfdVADELLIKRVLGRYSCKNCGKIYNIHFLQ------PKI--EHVCDVC 150
Cdd:PTZ00088  87 KGFILDGFPRNLKQCKELGKITNIDLFVNIY--LPRNILIKKLLGRRICNTCNRNFNIAHIRsdpydmPPIlpPADCEGC 164

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 490736863 151 SSSV-FDYRKDDNKEVIKKRIKVYKTETYPLIDYYKNSG 188
Cdd:PTZ00088 165 KGNPkLQKRSDDTEEIVAHRLNTYESTNSPIIQFFKNEN 203
PRK14527 PRK14527
adenylate kinase; Provisional
 2-210 6.10e-33

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 117.20  E-value: 6.10e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   2 IVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVfLLSSKYKNGY 81
Cdd:PRK14527   8 VVIFLGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRD-ELAGMEPVRV 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  82 ILDGYPRNLEQAKFFEAFIQKPQIKI---IYFDVADELLIKRVLGRysckncgkiynihflqpkiehvcdvcssSVFDYR 158
Cdd:PRK14527  87 IFDGFPRTLAQAEALDRLLEELGARLlavVLLEVPDEELIRRIVER----------------------------ARQEGR 138

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 490736863 159 KDDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKIL 210
Cdd:PRK14527 139 SDDNEETVRRRQQVYREQTQPLVDYYEARGHLKRVDGLGTPDEVYARILKAL 190
PLN02842 PLN02842
nucleotide kinase
 7-210 4.97e-32

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 121.12  E-value: 4.97e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   7 GPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFL-LSSKYKNGYILDG 85
Cdd:PLN02842   4 GAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRLsREDAKEKGWLLDG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  86 YPRNLEQAKFFEAFIQKPQIKIIyFDVADELLIKRVLGRYSCKNCGKIYNIHFLQPKIEHVcdvcsSSVFDYRKDDNKEV 165
Cdd:PLN02842  84 YPRSFAQAQSLEKLKIRPDIFIL-LDVPDEILIDRCVGRRLDPVTGKIYHIKNFPPESEEI-----KARLITRPDDTEEK 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 490736863 166 IKKRIKVYKTETYPLIDYYKNSGNfyIVNANKNEQEIENDIQKIL 210
Cdd:PLN02842 158 VKARLQIYKKNAEAILSTYSDIMV--KIDGNRPKEVVFEEISSLL 200
PLN02200 PLN02200
adenylate kinase family protein
 2-202 5.31e-31

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 113.45  E-value: 5.31e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   2 IVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKyKNGY 81
Cdd:PLN02200  45 ITFVLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKEMESSD-NNKF 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  82 ILDGYPRNLEQAKFFEAFIQKPQIKIIYFDVADELLIKRVLGRysckNCGKIynihflqpkiehvcdvcsssvfdyrkDD 161
Cdd:PLN02200 124 LIDGFPRTEENRIAFERIIGAEPNVVLFFDCPEEEMVKRVLNR----NQGRV--------------------------DD 173

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 490736863 162 NKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEI 202
Cdd:PLN02200 174 NIDTIKKRLKVFNALNLPVIDYYSKKGKLYTINAVGTVDEI 214
PRK13808 PRK13808
adenylate kinase; Provisional
 1-210 3.89e-27

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 105.35  E-value: 3.89e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   1 MIVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNG 80
Cdd:PRK13808   1 MRLILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISDRIEQPDAANG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  81 YILDGYPRNLEQAKFFEAFIQKPQIK---IIYFDVADELLIKRVLGRysckncgkiynIHFLQPKIEHVcdvcsssvfdy 157
Cdd:PRK13808  81 FILDGFPRTVPQAEALDALLKDKQLKldaVVELRVNEGALLARVETR-----------VAEMRARGEEV----------- 138

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490736863 158 RKDDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKIL 210
Cdd:PRK13808 139 RADDTPEVLAKRLASYRAQTEPLVHYYSEKRKLLTVDGMMTIDEVTREIGRVL 191
PRK14532 PRK14532
adenylate kinase; Provisional
 1-211 7.40e-27

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 101.44  E-value: 7.40e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   1 MIVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNG 80
Cdd:PRK14532   1 MNLILFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIEERLPEAEAAGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  81 YILDGYPRNLEQAKFFEAFIQKPQIKI---IYFDVADELLIKRVLGRYSCKNcgkiynihflqpkiehvcdvcsssvfdy 157
Cdd:PRK14532  81 AIFDGFPRTVAQAEALDKMLASRGQKIdvvIRLKVDDEALIERIVKRFEEQG---------------------------- 132

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 490736863 158 RKDDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKILK 211
Cdd:PRK14532 133 RPDDNPEVFVTRLDAYNAQTAPLLPYYAGQGKLTEVDGMGSIEAVAASIDAALE 186
PRK14529 PRK14529
adenylate kinase; Provisional
 1-186 8.07e-27

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 102.10  E-value: 8.07e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   1 MIVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIkVFLLSSKYKNG 80
Cdd:PRK14529   1 MNILIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVPDDITIPMI-LETLKQDGKNG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863  81 YILDGYPRNLEQAKFFEAFIQKPQIKIiyfDVADELLI------KRVLGRYSCKNCGKIYN---IHFLQPKiEHVCDVCS 151
Cdd:PRK14529  80 WLLDGFPRNKVQAEKLWEALQKEGMKL---DYVIEILLprevakNRIMGRRLCKNDNNHPNnifIDAIKPD-GDVCRVCG 155

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 490736863 152 SSVFDYRKDDNKEVIKKRIKVY---KTETYPLIDYYKN 186
Cdd:PRK14529 156 GELSTRADDQDEEAINKRHDIYydtETGTLAAAYFFKD 193
AAA_17 pfam13207
AAA domain;
6-124 3.99e-24

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 92.69  E-value: 3.99e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863    6 LGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKtsTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNGYILDG 85
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAK--ERGLVEDRDEMRKLPLEPQKELQKLAAERIAEEAGEGGVIVDG 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 490736863   86 YPRNLEQAKFFEAFIQ------KPQIkIIYFDVADELLIKRVLGR 124
Cdd:pfam13207  79 HPRIKTPAGYLPGLPVevlrelKPDA-IILLEADPEEILERRLKD 122
ADK_lid pfam05191
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ...
 124-161 9.76e-09

Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.


Pssm-ID: 461578 [Multi-domain]  Cd Length: 36  Bit Score: 49.38  E-value: 9.76e-09
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 490736863  124 RYSCKNCGKIYNIHFLQPKIEHVCDVCSSSVfdYRKDD 161
Cdd:pfam05191   1 RRVCPKCGRIYHVYFNPPKVEGVCDVCGGEL--VQRDD 36
cyt_kin_arch TIGR02173
cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. ...
 1-63 1.30e-08

cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. Members of this family are found in the archaea and in spirochaetes, and differ considerably from the common bacterial form of cytidylate kinase described by TIGR00017.


Pssm-ID: 274012 [Multi-domain]  Cd Length: 171  Bit Score: 52.43  E-value: 1.30e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490736863    1 MIVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEI 63
Cdd:TIGR02173   1 MIITISGPPGSGKTTVAKILAEKLSLKLISAGDIFRELAAKMGLDLIEFLNYAEENPEIDKKI 63
Kti12 COG4088
tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) ...
 1-125 2.67e-08

tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) [Translation, ribosomal structure and biogenesis, Defense mechanisms];


Pssm-ID: 443264 [Multi-domain]  Cd Length: 179  Bit Score: 51.65  E-value: 2.67e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   1 MIVIFLGPPGAGKGTQGKKIAKKIDLPHIAV----GDIFRTIIktstseaelinnyvkQGALIPNEIVNQVIKVF---LL 73
Cdd:COG4088    5 MLLILTGPPGSGKTTFAKALAQRLYAEGIAVallhSDDFRRFL---------------VNESFPKETYEEVVEDVrttTA 69

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 490736863  74 SSKYKNGY--ILDG---YPRNLEQakfFEAFIQ-KPQIKIIYFDVADELLIKRVLGRY 125
Cdd:COG4088   70 DNALDNGYsvIVDGtfyYRSWQRD---FRNLAKhKAPIHIIYLKAPLETALRRNRERG 124
PRK04182 PRK04182
cytidylate kinase; Provisional
 1-38 4.83e-07

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 47.88  E-value: 4.83e-07
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 490736863   1 MIVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTI 38
Cdd:PRK04182   1 MIITISGPPGSGKTTVARLLAEKLGLKHVSAGEIFREL 38
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 7-85 2.56e-05

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 42.47  E-value: 2.56e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863   7 GPPGAGKGTQGKKIAKKIDLPHIAVGDIfrtiiktSTSEaelINNYVKQGALIPN--EIVNQVIKVFllssKYKNGYILD 84
Cdd:cd02020    6 GPAGSGKSTVAKLLAKKLGLPYLDTGGI-------RTEE---VGKLASEVAAIPEvrKALDERQREL----AKKPGIVLE 71


                 .
gi 490736863  85 G 85
Cdd:cd02020   72 G 72
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 3-125 2.81e-04

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 39.60  E-value: 2.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490736863    3 VIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTstsEAELINNYVKQGALIPNEIVNQVIKVflLSSKYknGYI 82
Cdd:pfam13671   2 ILLVGLPGSGKSTLARRLLEELGAVRLSSDDERKRLFGE---GRPSISYYTDATDRTYERLHELARIA--LRAGR--PVI 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 490736863   83 LD-GYPRNLEQAKFFEAFIQ-KPQIKIIYFDVADELLIKRVLGRY 125
Cdd:pfam13671  75 LDaTNLRRDERARLLALAREyGVPVRIVVFEAPEEVLRERLAARA 119
PRK01184 PRK01184
flagellar hook-basal body complex protein FliE;
1-36 7.74e-04

flagellar hook-basal body complex protein FliE;


Pssm-ID: 234914 [Multi-domain]  Cd Length: 184  Bit Score: 38.77  E-value: 7.74e-04
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 490736863   1 MIVIFLGPPGAGKGtQGKKIAKKIDLPHIAVGDIFR 36
Cdd:PRK01184   2 KIIGVVGMPGSGKG-EFSKIAREMGIPVVVMGDVIR 36
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
1-40 3.57e-03

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 37.11  E-value: 3.57e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 490736863   1 MIVIFLGPPGAGKGTQGKKIAKKIDLPHIAvGDIFRTIIK 40
Cdd:COG1102    1 MVITISREPGSGGTTIAKRLAEKLGLPLYD-GEILREAAK 39
aroK PRK00131
shikimate kinase; Reviewed
 1-29 6.45e-03

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 35.94  E-value: 6.45e-03
                         10        20
                 ....*....|....*....|....*....
gi 490736863   1 MIVIFLGPPGAGKGTQGKKIAKKIDLPHI 29
Cdd:PRK00131   5 PNIVLIGFMGAGKSTIGRLLAKRLGYDFI 33
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 4-29 6.79e-03

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 35.99  E-value: 6.79e-03
                         10        20
                 ....*....|....*....|....*..
gi 490736863   4 IFL-GPPGAGKGTQGKKIAKKIDLPHI 29
Cdd:cd00464    2 IVLiGMMGAGKTTVGRLLAKALGLPFV 28
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 4-29 7.57e-03

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 35.87  E-value: 7.57e-03
                         10        20
                 ....*....|....*....|....*..
gi 490736863   4 IFL-GPPGAGKGTQGKKIAKKIDLPHI 29
Cdd:COG0703    1 IVLiGMMGAGKSTVGRLLAKRLGLPFV 27
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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