|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
31-343 |
0e+00 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 602.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 31 LPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDV 110
Cdd:PLN03025 1 LPWVEKYRPTKLDDIVGNEDAVSRLQVIARDGNMPNLILSGPPGTGKTTSILALAHELLGPNYKEAVLELNASDDRGIDV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 111 VRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTD 190
Cdd:PLN03025 81 VRNKIKMFAQKKVTLPPGRHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIEPIQSRCAIVRFSRLSD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 191 AQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDANI 270
Cdd:PLN03025 161 QEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALNNLQATHSGFGFVNQENVFKVCDQPHPLHVKNIVRNCLKGKF 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 55926133 271 DEAYKILAHLWHLGYSPEDVIGNIFRVCKTFPMAEYLKLEFIKEIGYTHMKVAEGVNSLLQMAGLLARLCQKT 343
Cdd:PLN03025 241 DDACDGLKQLYDLGYSPTDIITTLFRVVKNYDMPEFLKLEYLREIGFAHMRICDGVGSLLQLSGLLAKLCLVR 313
|
|
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
30-339 |
5.24e-128 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 369.20 E-value: 5.24e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 30 ELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGID 109
Cdd:PRK00440 4 EEIWVEKYRPRTLDEIVGQEEIVERLKSYVKEKNMPHLLFAGPPGTGKTTAALALARELYGEDWRENFLELNASDERGID 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 110 VVRNKIKMFAQQKvTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLT 189
Cdd:PRK00440 84 VIRNKIKEFARTA-PVGGAPFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPIQSRCAVFRFSPLK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 190 DAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDAN 269
Cdd:PRK00440 163 KEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINALQAAAATGKEVTEEAVYKITGTARPEEIREMIELALNGD 242
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 55926133 270 IDEAYKILAHLWHL-GYSPEDVIGNIFRVCKTFPMAEYLKLEFIKEIGYTHMKVAEGVNSLLQMAGLLARL 339
Cdd:PRK00440 243 FTEAREKLRDLMIDyGLSGEDIIKQIHREVWSLDIPEELKVELIDAIGEADFRITEGANERIQLEALLAKL 313
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
62-339 |
7.20e-71 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 236.27 E-value: 7.20e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 62 GNVPNIIiagppgtGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIKMFAQQKvtlPKG--RHKIIILDEAD 139
Cdd:PRK04132 571 GNLPTVL-------HNTTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFARTK---PIGgaSFKIIFLDEAD 640
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 140 SMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFT 219
Cdd:PRK04132 641 ALTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYI 720
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 220 AQGDMRQALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDANIDEAYKILAH-LWHLGYSPEDVIGNIFRVC 298
Cdd:PRK04132 721 AEGDMRRAINILQAAAALDDKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREiLLKQGLSGEDVLVQMHREV 800
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 55926133 299 KTFPMAEYLKLEFIKEIGYTHMKVAEGVNSLLQMAGLLARL 339
Cdd:PRK04132 801 FNLPIDEPKKVELADKIGEYNFRLVEGANEMIQLEALLAQF 841
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
33-339 |
5.01e-65 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 209.07 E-value: 5.01e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 33 WVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASN--DRGIDV 110
Cdd:PRK12402 5 WTEKYRPALLEDILGQDEVVERLSRAVDSPNLPHLLVQGPPGSGKTAAVRALARELYGDPWENNFTEFNVADffDQGKKY 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 111 VRNKiKMFAQQKVTLPK-----------------------GRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACN 167
Cdd:PRK12402 85 LVED-PRFAHFLGTDKRirsskidnfkhvlkeyasyrplsADYKTILLDNAEALREDAQQALRRIMEQYSRTCRFIIATR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 168 ASDKIIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVF 247
Cdd:PRK12402 164 QPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTLQTAALAAGEITMEAAY 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 248 KVC-DEPHPLLVKEMIQHCVDANIDEAYKILAHLwhL---GYSPEDVIGNIFRVCKTfPMAEYLKLEFIKEIGYTHMKVA 323
Cdd:PRK12402 244 EALgDVGTDEVIESLLDAAEAGDFTDARKTLDDL--LideGLSGGEVLEELLRVARS-RYRGDNLARLHRLAADADARLT 320
|
330
....*....|....*.
gi 55926133 324 EGVNSLLQMAGLLARL 339
Cdd:PRK12402 321 DGANDRIQLEALLAEL 336
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
48-341 |
3.27e-49 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 166.69 E-value: 3.27e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 48 NEDTVSRLEVFAREGNVP-NIIIAGPPGTGKTTSILCLARALLGPALKDA------------------VLELNA---SND 105
Cdd:COG0470 1 QEEAWEQLLAAAESGRLPhALLLHGPPGIGKTTLALALARDLLCENPEGGkacgqchsrlmaagnhpdLLELNPeekSDQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 106 RGIDVVRnKIKMFAQQKVTLpkGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRY 185
Cdd:COG0470 81 IGIDQIR-ELGEFLSLTPLE--GGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRF 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 186 TKLTDAQVLSRLmnviEKEKVpyTDDGLEAIIFTAQGDMRQALNNLQsTFSGFGYInSENVFKVCDEPHPLlvkEMIQHC 265
Cdd:COG0470 158 RPPSEEEALAWL----REEGV--DEDALEAILRLAGGDPRAAINLLQ-ALAGRKEL-LEDLAALLSRDRAL---ELLDAL 226
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 55926133 266 VDANIDEAYKILAHLWHlgyspeDVIGnifrvcktFPMAEYLKLEFIKEIGYTHMKVAEGVNSLLQMAGLLARLCQ 341
Cdd:COG0470 227 LKAEALELLDWLLKWLL------DNLP--------LEYAGEDLARAYEALSEADRRLGRYANDRLLLEALLAKLGR 288
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
25-243 |
2.20e-42 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 149.37 E-value: 2.20e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 25 TTGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIII-AGPPGTGKTTSILCLARALlgpalkDA-VLELNA 102
Cdd:PHA02544 3 TVNPNEFMWEQKYRPSTIDECILPAADKETFKSIVKKGRIPNMLLhSPSPGTGKTTVAKALCNEV------GAeVLFVNG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 103 SNDRgIDVVRNKIKMFAQQkVTLpKGRHKIIILDEAD-SMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCA 181
Cdd:PHA02544 77 SDCR-IDFVRNRLTRFAST-VSL-TGGGKVIIIDEFDrLGLADAQRHLRSFMEAYSKNCSFIITANNKNGIIEPLRSRCR 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 55926133 182 VLRYTKLTDA-------QVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQStFSGFGYINS 243
Cdd:PHA02544 154 VIDFGVPTKEeqiemmkQMIVRCKGILEAEGVEVDMKVLAALVKKNFPDFRRTINELQR-YASTGKIDA 221
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
31-246 |
1.26e-34 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 132.35 E-value: 1.26e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 31 LPWVEKYRPVKLNEIVGNEDTVSRLEVFARE---GNVPN-IIIAGPPGTGKTTSILCLARALLGPalkdaVLELNASNDR 106
Cdd:PRK04195 2 MPWVEKYRPKTLSDVVGNEKAKEQLREWIESwlkGKPKKaLLLYGPPGVGKTSLAHALANDYGWE-----VIELNASDQR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 107 GIDVVRNKIKMFAQQKvTLPKGRHKIIILDEADSM---TD-GAQQALRRTMeiysKTTRFALACNASD---KIIEPIQSR 179
Cdd:PRK04195 77 TADVIERVAGEAATSG-SLFGARRKLILLDEVDGIhgnEDrGGARAILELI----KKAKQPIILTANDpydPSLRELRNA 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 55926133 180 CAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENV 246
Cdd:PRK04195 152 CLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSAINDLQAIAEGYGKLTLEDV 218
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
29-286 |
1.47e-32 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 126.48 E-value: 1.47e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 29 YElPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARAL--LGP-------------- 91
Cdd:PRK14953 3 YI-PFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHAyIFAGPRGTGKTTIARILAKVLncLNPqegepcgkcencve 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 92 ----ALKDAVlELNASNDRGIDVVRNKIKMFAQQKVtlpKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACN 167
Cdd:PRK14953 82 idkgSFPDLI-EIDAASNRGIDDIRALRDAVSYTPI---KGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 168 ASDKIIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNL-QSTFSGFGYINS--- 243
Cdd:PRK14953 158 EYDKIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLdQASTYGEGKVTIkvv 237
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 55926133 244 ENVFKVCDEPHpllVKEMIQHCVDANIDEAYKILAHLWHLGYS 286
Cdd:PRK14953 238 EEFLGIVSQES---VRKFLNLLLESDVDEAIKFLRTLEEKGYN 277
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
39-341 |
3.49e-30 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 117.60 E-value: 3.49e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 39 PVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARALLGPALKDA-------------------VL 98
Cdd:COG2812 6 PQTFDDVVGQEHVVRTLKNALASGRLAHaYLFTGPRGVGKTTLARILAKALNCENGPTGepcgecescraiaagshpdVI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 99 EL--NASNdRGIDVVRNkIkmfaQQKVTLP--KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIE 174
Cdd:COG2812 86 EIdaEASN-IGVDDIRE-L----IEKVSYApvEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 175 PIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTfSGFGYINSENvfkvcdeph 254
Cdd:COG2812 160 TILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQA-IAFGLLDRRE--------- 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 255 plLVKEMIQHCVDANIDEAYKILAHLWHLGYSPEDVIG---NIFR---VCKTFPMAEYL----KLEFIKEI--------- 315
Cdd:COG2812 230 --LLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDdllSLLRdllLLKLGPDAELLvnedERERLQELarrlsperl 307
|
330 340 350
....*....|....*....|....*....|....*
gi 55926133 316 ---------GYTHMKVAegVNSLLQMAGLLARLCQ 341
Cdd:COG2812 308 lraiqilleARRELERN--VNPRLALEMLLLRLAR 340
|
|
| Rep_fac_C |
pfam08542 |
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication ... |
253-338 |
2.82e-29 |
|
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication factor-C) protein of the clamp loader complex which binds to the DNA sliding clamp (proliferating cell nuclear antigen, PCNA). The five modules of RFC assemble into a right-handed spiral, which results in only three of the five RFC subunits (RFC-A, RFC-B and RFC-C) making contact with PCNA, leaving a wedge-shaped gap between RFC-E and the PCNA clamp-loader complex. The C-terminal is vital for the correct orientation of RFC-E with respect to RFC-A.
Pssm-ID: 462513 [Multi-domain] Cd Length: 87 Bit Score: 107.95 E-value: 2.82e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 253 PHPLLVKEMIQHCVDANIDEAYKIL-AHLWHLGYSPEDVIGNIFRVCKTFPMAEYLKLEFIKEIGYTHMKVAEGVNSLLQ 331
Cdd:pfam08542 1 PHPEDIEEILNSCLNGDFDEAYKKVrELLVEKGYSLQDIITQLHRVVKSLDLPEEVKLELLEKLGEIEYRLSEGASEKLQ 80
|
....*..
gi 55926133 332 MAGLLAR 338
Cdd:pfam08542 81 LSALLAA 87
|
|
| PRK07133 |
PRK07133 |
DNA polymerase III subunits gamma and tau; Validated |
31-301 |
4.10e-25 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235943 [Multi-domain] Cd Length: 725 Bit Score: 106.44 E-value: 4.10e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 31 LPWVEKYRPVKLNEIVGNEDTVSRLEvfaregnvpNII----------IAGPPGTGKTTSILCLARAL--------LGPA 92
Cdd:PRK07133 6 KALYRKYRPKTFDDIVGQDHIVQTLK---------NIIksnkishaylFSGPRGTGKTSVAKIFANALncshktdlLEPC 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 93 LK---------DaVLELNASNDRGIDVVR---NKIKMFAQQkvtlpkGRHKIIILDEADSMTDGAQQALRRTMEIYSKTT 160
Cdd:PRK07133 77 QEcienvnnslD-IIEMDAASNNGVDEIReliENVKNLPTQ------SKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 161 RFALACNASDKIIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQ--STFSGf 238
Cdd:PRK07133 150 IFILATTEVHKIPLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEqvSIFGN- 228
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 55926133 239 GYINSENVFK----VCDEPHPLLVKEMIQHcvdaNIDEAYKILAHLWHLGYSPEDVIGNIFRVCKTF 301
Cdd:PRK07133 229 NKITLKNVEElfglVSNENLINLLNLLYSK----DIKEVLNILNQIKEQGIDPELLLISLINLVKEF 291
|
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
35-231 |
9.40e-24 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 100.93 E-value: 9.40e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 35 EKYRPVKLNEIVGNEDTVSR---LEVFAREGNVPNIIIAGPPGTGKTTsilcLARALLGpALKDAVLELNASNDrGIDVV 111
Cdd:PRK13342 4 ERMRPKTLDEVVGQEHLLGPgkpLRRMIEAGRLSSMILWGPPGTGKTT----LARIIAG-ATDAPFEALSAVTS-GVKDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 112 RnkiKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQAL-----RRTMEIYSKTTRfalacNASDKIIEPIQSRCAVLRYT 186
Cdd:PRK13342 78 R---EVIEEARQRRSAGRRTILFIDEIHRFNKAQQDALlphveDGTITLIGATTE-----NPSFEVNPALLSRAQVFELK 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 55926133 187 KLTDA---QVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNL 231
Cdd:PRK13342 150 PLSEEdieQLLKRALEDKERGLVELDDEALDALARLANGDARRALNLL 197
|
|
| PRK14962 |
PRK14962 |
DNA polymerase III subunits gamma and tau; Provisional |
36-291 |
2.56e-23 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 100.22 E-value: 2.56e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGnEDTVSRLEVFAREGNVPN--IIIAGPPGTGKTTSILCLARALLGPALKDA----------------- 96
Cdd:PRK14962 7 KYRPKTFSEVVG-QDHVKKLIINALKKNSIShaYIFAGPRGTGKTTVARILAKSLNCENRKGVepcnecracrsidegtf 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 97 --VLELNASNDRGIDVVRnKIKMFAQQKVTLpkGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIE 174
Cdd:PRK14962 86 mdVIELDAASNRGIDEIR-KIRDAVGYRPME--GKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 175 PIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQ--STFSGfGYINSENVfkvcDE 252
Cdd:PRK14962 163 TIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEqvWKFSE-GKITLETV----HE 237
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 55926133 253 PHPLLVKEMIQHCVDA----NIDEAYKILAHLWHLGYSPEDVI 291
Cdd:PRK14962 238 ALGLIPIEVVRDYINAifngDVKRVFTVLDDVYYSGKDYEVLI 280
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
46-180 |
1.24e-22 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 92.21 E-value: 1.24e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 46 VGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPalKDAVLELNASNDRGIDVVRNKIKMFA--QQKV 123
Cdd:cd00009 1 VGQEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRP--GAPFLYLNASDLLEGLVVAELFGHFLvrLLFE 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 55926133 124 TLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTT------RFALACNASD--KIIEPIQSRC 180
Cdd:cd00009 79 LAEKAKPGVLFIDEIDSLSRGAQNALLRVLETLNDLRidrenvRVIGATNRPLlgDLDRALYDRL 143
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
36-237 |
1.43e-22 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 97.25 E-value: 1.43e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARALLGPALKDA-------VLELNASNDRG 107
Cdd:PRK14970 10 KYRPQTFDDVVGQSHITNTLLNAIENNHLAQaLLFCGPRGVGKTTCARILARKINQPGYDDPnedfsfnIFELDAASNNS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 108 IDVVRNKIKmfaQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTK 187
Cdd:PRK14970 90 VDDIRNLID---QVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIFDFKR 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 55926133 188 LTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALN--NLQSTFSG 237
Cdd:PRK14970 167 ITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSifDRVVTFCG 218
|
|
| HLD_clamp_RFC |
cd18140 |
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ... |
188-250 |
1.69e-21 |
|
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.
Pssm-ID: 350842 [Multi-domain] Cd Length: 63 Bit Score: 86.43 E-value: 1.69e-21
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 55926133 188 LTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVFKVC 250
Cdd:cd18140 1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQAAAAGGGVITEEDVYEVA 63
|
|
| PRK14963 |
PRK14963 |
DNA polymerase III subunits gamma and tau; Provisional |
35-227 |
6.77e-19 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184927 [Multi-domain] Cd Length: 504 Bit Score: 87.59 E-value: 6.77e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 35 EKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARAL--LGPALKDA--------------- 96
Cdd:PRK14963 6 QRARPITFDEVVGQEHVKEVLLAALRQGRLGHAyLFSGPRGVGKTTTARLIAMAVncSGEDPKPCgecesclavrrgahp 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 97 -VLELNASNDRGIDVVRNkikmfAQQKVTLP--KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKII 173
Cdd:PRK14963 86 dVLEIDAASNNSVEDVRD-----LREKVLLAplRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 55926133 174 EPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQA 227
Cdd:PRK14963 161 PTILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDA 214
|
|
| PRK05896 |
PRK05896 |
DNA polymerase III subunits gamma and tau; Validated |
35-232 |
8.16e-19 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235638 [Multi-domain] Cd Length: 605 Bit Score: 87.59 E-value: 8.16e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 35 EKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARALLGPALKDA----------------- 96
Cdd:PRK05896 8 RKYRPHNFKQIIGQELIKKILVNAILNNKLTHaYIFSGPRGIGKTSIAKIFAKAINCLNPKDGdccnscsvcesintnqs 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 97 --VLELNASNDRGIDVVRNKIKMFAQQKVTLPKgrhKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIE 174
Cdd:PRK05896 88 vdIVELDAASNNGVDEIRNIIDNINYLPTTFKY---KVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQKIPL 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 55926133 175 PIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQ 232
Cdd:PRK05896 165 TIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILD 222
|
|
| PRK14964 |
PRK14964 |
DNA polymerase III subunits gamma and tau; Provisional |
36-298 |
3.89e-18 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237870 [Multi-domain] Cd Length: 491 Bit Score: 85.22 E-value: 3.89e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSI----LCLaRALLGP------------ALKDA-- 96
Cdd:PRK14964 6 KYRPSSFKDLVGQDVLVRILRNAFTLNKIPQsILLVGASGVGKTTCAriisLCL-NCSNGPtsdpcgtchnciSIKNSnh 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 97 --VLELNASNDRGIDvvrnKIKMFAQQKVTLP-KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKII 173
Cdd:PRK14964 85 pdVIEIDAASNTSVD----DIKVILENSCYLPiSSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 174 EPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNL-QSTFSGFGYINSENVFKV--C 250
Cdd:PRK14964 161 VTIISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLeQAAIYSNNKISEKSVRDLlgC 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 55926133 251 DEPHPLLvkEMIQHCVDANIDEAYKILAHLWHLgYSP----EDVIGNIFRVC 298
Cdd:PRK14964 241 VDKHILE--DLVEAILLGDAQSALNVFRELCNT-SNPviilEGMLQIIYEIC 289
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
36-246 |
7.28e-18 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 84.76 E-value: 7.28e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARALLGPALKDA------------------ 96
Cdd:PRK08691 9 KWRPKTFADLVGQEHVVKALQNALDEGRLHHAyLLTGTRGVGKTTIARILAKSLNCENAQHGepcgvcqsctqidagryv 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 97 -VLELNASNDRGIDVVRNKIKMfAQQKVTLpkGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 175
Cdd:PRK08691 89 dLLEIDAASNTGIDNIREVLEN-AQYAPTA--GKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKVPVT 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 55926133 176 IQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNL-QSTFSGFGYINSENV 246
Cdd:PRK08691 166 VLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLdQAIALGSGKVAENDV 237
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
36-231 |
6.81e-17 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 81.71 E-value: 6.81e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARAL---LGPALKDA--------------- 96
Cdd:PRK14965 9 KYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHaFLFTGARGVGKTSTARILAKALnceQGLTAEPCnvcppcveitegrsv 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 97 -VLELNASNDRGIDVVR---NKIKMfaqqkvtLP-KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDK 171
Cdd:PRK14965 89 dVFEIDGASNTGVDDIRelrENVKY-------LPsRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHK 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 172 IIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNL 231
Cdd:PRK14965 162 VPITILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTL 221
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
32-231 |
2.51e-16 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 80.11 E-value: 2.51e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 32 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNV-PNIIIAGPPGTGKTTSILCLARAL-------------------LGP 91
Cdd:PRK14959 5 SLTARYRPQTFAEVAGQETVKAILSRAAQENRVaPAYLFSGTRGVGKTTIARIFAKALncetaptgepcntceqcrkVTQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 92 ALKDAVLELNASNDRGIDVVRNKIKMFAQQKVtlpKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDK 171
Cdd:PRK14959 85 GMHVDVVEIDGASNRGIDDAKRLKEAIGYAPM---EGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPHK 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 172 IIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNL 231
Cdd:PRK14959 162 FPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLL 221
|
|
| PRK08451 |
PRK08451 |
DNA polymerase III subunits gamma and tau; Validated |
36-314 |
6.02e-16 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236267 [Multi-domain] Cd Length: 535 Bit Score: 78.54 E-value: 6.02e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARALL---GP-------------ALKDA-- 96
Cdd:PRK08451 7 KYRPKHFDELIGQESVSKTLSLALDNNRLAHAyLFSGLRGSGKTSSARIFARALVceqGPsstpcdtciqcqsALENRhi 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 97 -VLELNASNDRGIDVVRNKIKmfaQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 175
Cdd:PRK08451 87 dIIEMDAASNRGIDDIRELIE---QTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKLPAT 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 176 IQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNL-QSTFSGFGYINSENVFKVCDEPH 254
Cdd:PRK08451 164 ILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLdQAIIYCKNAITESKVADMLGLLD 243
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 55926133 255 PLLVKEMIQHCvdANIDEAyKILAHLWHL-GYSPEDVIGNifrvcktfpMAEYLKLEFIKE 314
Cdd:PRK08451 244 PSKLEDFFQAI--LNQDKE-KLFELLKELeDYEAEMVLDE---------MMLFLKEKFLSK 292
|
|
| RarA |
COG2256 |
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ... |
38-231 |
2.70e-15 |
|
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];
Pssm-ID: 441857 [Multi-domain] Cd Length: 439 Bit Score: 76.25 E-value: 2.70e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 38 RPVKLNEIVGNEDTVSR---LEVFAREGNVPNIIIAGPPGTGKTTsilcLARALLGpALKDAVLELNASNDrGIDVVRnk 114
Cdd:COG2256 20 RPRTLDEVVGQEHLLGPgkpLRRAIEAGRLSSMILWGPPGTGKTT----LARLIAN-ATDAEFVALSAVTS-GVKDIR-- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 115 iKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTME------IYSkTTRfalacNASDKIIEPIQSRCAVLRYTKL 188
Cdd:COG2256 92 -EVIEEARERRAYGRRTILFVDEIHRFNKAQQDALLPHVEdgtitlIGA-TTE-----NPSFEVNSALLSRCRVFVLKPL 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 55926133 189 TDA---QVLSRLMNVIEK----EKVPYTDDGLEAIIFTAQGDMRQALNNL 231
Cdd:COG2256 165 SEEdleQLLERALADDERglggYKLELDDEALEALARLADGDARRALNAL 214
|
|
| PRK06305 |
PRK06305 |
DNA polymerase III subunits gamma and tau; Validated |
36-227 |
5.76e-15 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180523 [Multi-domain] Cd Length: 451 Bit Score: 75.58 E-value: 5.76e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLE---VFAREGNVpnIIIAGPPGTGKTTSILCLARAL----------------------LG 90
Cdd:PRK06305 10 KYRPQTFSEILGQDAVVAVLKnalRFNRAAHA--YLFSGIRGTGKTTLARIFAKALncqnptedqepcnqcasckeisSG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 91 PALKdaVLELNASNDRGIDVVR--NKIKMFaqqkvTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNA 168
Cdd:PRK06305 88 TSLD--VLEIDGASHRGIEDIRqiNETVLF-----TPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTE 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 55926133 169 SDKIIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQA 227
Cdd:PRK06305 161 IHKIPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDA 219
|
|
| PRK14956 |
PRK14956 |
DNA polymerase III subunits gamma and tau; Provisional |
36-229 |
9.84e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184920 [Multi-domain] Cd Length: 484 Bit Score: 74.98 E-value: 9.84e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARAL-------------------LGPALKD 95
Cdd:PRK14956 11 KYRPQFFRDVIHQDLAIGALQNALKSGKIGHAyIFFGPRGVGKTTIARILAKRLncenpignepcnectscleITKGISS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 96 AVLELNASNDRGIDVVRnkiKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 175
Cdd:PRK14956 91 DVLEIDAASNRGIENIR---ELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHKIPET 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 55926133 176 IQSRCAVLRYTKLTdaqvLSRLMNVIEK----EKVPYTDDGLEAIIFTAQGDMRQALN 229
Cdd:PRK14956 168 ILSRCQDFIFKKVP----LSVLQDYSEKlckiENVQYDQEGLFWIAKKGDGSVRDMLS 221
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
36-239 |
2.34e-14 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 74.08 E-value: 2.34e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARAL----LGPALKDA-------------- 96
Cdd:PRK14950 9 KWRSQTFAELVGQEHVVQTLRNAIAEGRVAHAyLFTGPRGVGKTSTARILAKAVncttNDPKGRPCgtcemcraiaegsa 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 97 --VLELNASNDRGIDVVRnKIKMFAQQKVTLpkGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIE 174
Cdd:PRK14950 89 vdVIEMDAASHTSVDDAR-EIIERVQFRPAL--ARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHKVPA 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 55926133 175 PIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFG 239
Cdd:PRK14950 166 TILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYG 230
|
|
| PRK06645 |
PRK06645 |
DNA polymerase III subunits gamma and tau; Validated |
31-236 |
7.49e-13 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180643 [Multi-domain] Cd Length: 507 Bit Score: 69.12 E-value: 7.49e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 31 LPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARAL--LGPALKDA----------- 96
Cdd:PRK06645 9 IPFARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGgYLLTGIRGVGKTTSARIIAKAVncSALITENTtiktceqctnc 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 97 ----------VLELNASNDRGIDVVRNKIKMfAQQKVTlpKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALAC 166
Cdd:PRK06645 89 isfnnhnhpdIIEIDAASKTSVDDIRRIIES-AEYKPL--QGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFAT 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 167 NASDKIIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFS 236
Cdd:PRK06645 166 TEVQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAAS 235
|
|
| PRK14957 |
PRK14957 |
DNA polymerase III subunits gamma and tau; Provisional |
36-281 |
8.74e-13 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184921 [Multi-domain] Cd Length: 546 Bit Score: 68.95 E-value: 8.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLeVFAREGNVPN--IIIAGPPGTGKTTSILCLARAL-------LGPALKDA---------- 96
Cdd:PRK14957 9 KYRPQSFAEVAGQQHALNSL-VHALETQKVHhaYLFTGTRGVGKTTLGRLLAKCLncktgvtAEPCNKCEncvainnnsf 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 97 --VLELNASNDRGIDVVRnkiKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIE 174
Cdd:PRK14957 88 idLIEIDAASRTGVEETK---EILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIPV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 175 PIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFS-------------GFGYI 241
Cdd:PRK14957 165 TILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISfcggelkqaqikqMLGII 244
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 55926133 242 NSENVFKVCD---EPHPLLVKEMIQH--CVDANIDEAYKILAHLW 281
Cdd:PRK14957 245 DSEEVYSIINaiiDNDPKAILPAIKNlaLTESSADAVLDRIAEIW 289
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
36-246 |
1.28e-12 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 68.65 E-value: 1.28e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTT-------SILCLARALLGPALKDA----------- 96
Cdd:PRK14971 10 KYRPSTFESVVGQEALTTTLKNAIATNKLAHaYLFCGPRGVGKTTcarifakTINCQNLTADGEACNECescvafneqrs 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 97 --VLELNASNDRGIDVVRNKIKmfaQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIE 174
Cdd:PRK14971 90 ynIHELDAASNNSVDDIRNLIE---QVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHKILP 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 55926133 175 PIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALN--NLQSTFSGfGYINSENV 246
Cdd:PRK14971 167 TILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSifDQVVSFTG-GNITYKSV 239
|
|
| PRK06647 |
PRK06647 |
DNA polymerase III subunits gamma and tau; Validated |
36-291 |
1.96e-12 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235845 [Multi-domain] Cd Length: 563 Bit Score: 67.87 E-value: 1.96e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARAL---LGPALKDA--------------- 96
Cdd:PRK06647 9 KRRPRDFNSLEGQDFVVETLKHSIESNKIANAyIFSGPRGVGKTSSARAFARCLncvNGPTPMPCgecsscksidndnsl 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 97 -VLELNASNDRGIDVVRnKIK---MFAQQkvtlpKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKI 172
Cdd:PRK06647 89 dVIEIDGASNTSVQDVR-QIKeeiMFPPA-----SSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 173 IEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQA--LNNLQSTFSGfGYINSENVFK-- 248
Cdd:PRK06647 163 PATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAytLFDQVVSFSD-SDITLEQIRSkm 241
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 55926133 249 --VCDEphplLVKEMIQHCVDANIDEAYKILAHLWHLGYSPEDVI 291
Cdd:PRK06647 242 glTGDE----FLEKLASSILNEDAKELLCVLDSVFLSGVSVEQFL 282
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
30-77 |
4.13e-12 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 67.17 E-value: 4.13e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 55926133 30 ELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGK 77
Cdd:PRK04132 6 EKPWVEKYRPQRLDDIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGK 53
|
|
| PRK14955 |
PRK14955 |
DNA polymerase III subunits gamma and tau; Provisional |
36-280 |
5.05e-12 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184919 [Multi-domain] Cd Length: 397 Bit Score: 66.45 E-value: 5.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARAL-------------------------- 88
Cdd:PRK14955 9 KYRPKKFADITAQEHITRTIQNSLRMGRVGHgYIFSGLRGVGKTTAARVFAKAVncqrmiddadylqevtepcgecescr 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 89 ---LGPALKdaVLELNASNDRGID---VVRNKIKMFAQqkvtlpKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRF 162
Cdd:PRK14955 89 dfdAGTSLN--ISEFDAASNNSVDdirLLRENVRYGPQ------KGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 163 ALACNASDKIIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQS--------- 233
Cdd:PRK14955 161 IFATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQviafsvese 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 55926133 234 -----TFSG----FGYINSENVFKVCD---EPHPLLVKEMIQHCVDANIDEA---YKILAHL 280
Cdd:PRK14955 241 gegsiRYDKvaelLNYIDDEHFFAVTDavaDGDAVAMLDVAQFVIRNGYDEQdflEKLIEHL 302
|
|
| PRK14969 |
PRK14969 |
DNA polymerase III subunits gamma and tau; Provisional |
36-246 |
5.62e-12 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237873 [Multi-domain] Cd Length: 527 Bit Score: 66.70 E-value: 5.62e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLeVFAREGNVPN--IIIAGPPGTGKTTSILCLARAL-------LGPALKDA---------- 96
Cdd:PRK14969 9 KWRPKSFSELVGQEHVVRAL-TNALEQQRLHhaYLFTGTRGVGKTTLARILAKSLncetgvtATPCGVCSacleidsgrf 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 97 --VLELNASNDRGIDVVRNKIKMfAQQKVTlpKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIE 174
Cdd:PRK14969 88 vdLIEVDAASNTQVDAMRELLDN-AQYAPT--RGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQKIPV 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 55926133 175 PIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNL-QSTFSGFGYINSENV 246
Cdd:PRK14969 165 TVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLdQAIAYGGGTVNESEV 237
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
67-185 |
1.37e-11 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 61.07 E-value: 1.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 67 IIIAGPPGTGKTTsilcLARALLGpALKDAVLELNASN--DRGIDVVRNKI-KMFAQQKVTLPkgrhKIIILDEADSM-- 141
Cdd:pfam00004 1 LLLYGPPGTGKTT----LAKAVAK-ELGAPFIEISGSElvSKYVGESEKRLrELFEAAKKLAP----CVIFIDEIDALag 71
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 55926133 142 ---------TDGAQQALRRTMEIYSKTTR---FALACNASDKIIEPIQSRCAVLRY 185
Cdd:pfam00004 72 srgsggdseSRRVVNQLLTELDGFTSSNSkviVIAATNRPDKLDPALLGRFDRIIE 127
|
|
| PRK14961 |
PRK14961 |
DNA polymerase III subunits gamma and tau; Provisional |
36-246 |
1.53e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184925 [Multi-domain] Cd Length: 363 Bit Score: 64.83 E-value: 1.53e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARAL---LG----PALKDA----------- 96
Cdd:PRK14961 9 KWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAwLLSGTRGVGKTTIARLLAKSLncqNGitsnPCRKCIickeiekglcl 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 97 -VLELNASNDRGIDVVRnkiKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 175
Cdd:PRK14961 89 dLIEIDAASRTKVEEMR---EILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVEKIPKT 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 55926133 176 IQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFS-GFGYINSENV 246
Cdd:PRK14961 166 ILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINlGKGNINIKNV 237
|
|
| PRK09112 |
PRK09112 |
DNA polymerase III subunit delta'; Validated |
39-228 |
2.18e-11 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 169667 [Multi-domain] Cd Length: 351 Bit Score: 64.29 E-value: 2.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 39 PVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARALL-------GP-ALKD-------------- 95
Cdd:PRK09112 19 PSENTRLFGHEEAEAFLAQAYREGKLHHaLLFEGPEGIGKATLAFHLANHILshpdpaeAPeTLADpdpaspvwrqiaqg 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 96 ---AVLELNASNDRG---------IDVVRNKIKMFAQqkvTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFA 163
Cdd:PRK09112 99 ahpNLLHITRPFDEKtgkfktaitVDEIRRVGHFLSQ---TSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFI 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 55926133 164 LACNASDKIIEPIQSRCAVLRYTKLTDAQVLSRLMNVIekEKVPYTDDGLEAIIFTAQGDMRQAL 228
Cdd:PRK09112 176 LISHSSGRLLPTIRSRCQPISLKPLDDDELKKALSHLG--SSQGSDGEITEALLQRSKGSVRKAL 238
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
36-280 |
2.23e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 64.96 E-value: 2.23e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARAL-------------------------- 88
Cdd:PRK14954 9 KYRPSKFADITAQEHITHTIQNSLRMDRVGHgYIFSGLRGVGKTTAARVFAKAVncqrmiddpvylqevtepcgecescr 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 89 ---LGPALKdaVLELNASNDRGID---VVRNKIKMFAQqkvtlpKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRF 162
Cdd:PRK14954 89 dfdAGTSLN--ISEFDAASNNSVDdirQLRENVRYGPQ------KGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 163 ALACNASDKIIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQS--TFSG--- 237
Cdd:PRK14954 161 IFATTELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQviAFSVgse 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 55926133 238 -------------FGYINSENVFKVCD---EPHPLLVKEMIQHCVDANIDEA---YKILAHL 280
Cdd:PRK14954 241 aekviayqgvaelLNYIDDEQFFDVTDaiaENDAVKMLEVARFVIDNGYDEQdflEKLIEHF 302
|
|
| PRK05563 |
PRK05563 |
DNA polymerase III subunits gamma and tau; Validated |
36-307 |
3.51e-11 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235505 [Multi-domain] Cd Length: 559 Bit Score: 64.12 E-value: 3.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLEvfaregnvpNIII----------AGPPGTGKTTSILCLARALLGPALKDA--------- 96
Cdd:PRK05563 9 KWRPQTFEDVVGQEHITKTLK---------NAIKqgkishaylfSGPRGTGKTSAAKIFAKAVNCLNPPDGepcneceic 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 97 ----------VLELNASNDRGIDVVRNKIkmfaqQKVTLP--KGRHKIIILDEADSMTDGAQQALRRTME------Iysk 158
Cdd:PRK05563 80 kaitngslmdVIEIDAASNNGVDEIRDIR-----DKVKYApsEAKYKVYIIDEVHMLSTGAFNALLKTLEeppahvI--- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 159 ttrFALACNASDKIIEPIQSRCAvlRY--TKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQAL-------- 228
Cdd:PRK05563 152 ---FILATTEPHKIPATILSRCQ--RFdfKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALsildqais 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 229 ---------NNLQSTfsgfGYINSENVFKvcdephpllvkeMIQHCVDANIDEAYKILAHLWHLGYSP----EDVIGnIF 295
Cdd:PRK05563 227 fgdgkvtyeDALEVT----GSVSQEALDD------------LVDAIVEGDVAKALKILEELLDEGKDPnrfiEDLIY-YL 289
|
330
....*....|....*
gi 55926133 296 R---VCKTFPMAEYL 307
Cdd:PRK05563 290 RdllLVKTSPELEIL 304
|
|
| PRK14960 |
PRK14960 |
DNA polymerase III subunit gamma/tau; |
36-246 |
4.12e-11 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237868 [Multi-domain] Cd Length: 702 Bit Score: 64.30 E-value: 4.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGnEDTVSRLEVFARE-GNVPNI-IIAGPPGTGKTTSILCLARAL-----LGPALKDAVLELNASND-RG 107
Cdd:PRK14960 8 KYRPRNFNELVG-QNHVSRALSSALErGRLHHAyLFTGTRGVGKTTIARILAKCLncetgVTSTPCEVCATCKAVNEgRF 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 108 IDVV------RNKIKMFAQQKVTLP----KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQ 177
Cdd:PRK14960 87 IDLIeidaasRTKVEDTRELLDNVPyaptQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPITVI 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 178 SRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALN-NLQSTFSGFGYINSENV 246
Cdd:PRK14960 167 SRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSlTDQAIAYGQGAVHHQDV 236
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
36-228 |
5.06e-11 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 63.74 E-value: 5.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARAL--LGPALK-----------------D 95
Cdd:PRK12323 9 KWRPRDFTTLVGQEHVVRALTHALEQQRLHHAyLFTGTRGVGKTTLSRILAKSLncTGADGEggitaqpcgqcracteiD 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 96 A-----VLELNASNDRGIDvvrnKIKMFAQQKVTLP-KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNAS 169
Cdd:PRK12323 89 AgrfvdYIEMDAASNRGVD----EMAQLLDKAVYAPtAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATTDP 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 55926133 170 DKIIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQAL 228
Cdd:PRK12323 165 QKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDAL 223
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
66-202 |
5.70e-11 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 60.08 E-value: 5.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 66 NIIIAGPPGTGKTTSILCLARALLGPALKdaVLELNASNDRGIDVVRNKIKMFAQQKVTLPKG-------------RHKI 132
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPGGG--VIYIDGEDILEEVLDQLLLIIVGGKKASGSGElrlrlalalarklKPDV 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 133 IILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASdkIIepiqsrCAVLRYTKLTDAQVLSRLMNVIE 202
Cdd:smart00382 82 LILDEITSLLDAEQEALLLLLEELRLLLLLKSEKNLT--VI------LTTNDEKDLGPALLRRRFDRRIV 143
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
36-228 |
3.60e-10 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 61.27 E-value: 3.60e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLE------------VFAregnvpniiiaGPPGTGKTTSILCLARAL--LGP---------- 91
Cdd:PRK14951 9 KYRPRSFSEMVGQEHVVQALTnaltqqrlhhayLFT-----------GTRGVGKTTVSRILAKSLncQGPdgqggitatp 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 92 -----ALKDA-------VLELNASNDRGIDvvrnKIKMFAQQKVTLP-KGRHKIIILDEADSMTDGAQQALRRTMEIYSK 158
Cdd:PRK14951 78 cgvcqACRDIdsgrfvdYTELDAASNRGVD----EVQQLLEQAVYKPvQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPE 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 159 TTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQAL 228
Cdd:PRK14951 154 YLKFVLATTDPQKVPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDAL 223
|
|
| PRK14958 |
PRK14958 |
DNA polymerase III subunits gamma and tau; Provisional |
36-263 |
7.69e-10 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184922 [Multi-domain] Cd Length: 509 Bit Score: 60.13 E-value: 7.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGID----- 109
Cdd:PRK14958 9 KWRPRCFQEVIGQAPVVRALSNALDQQYLHHAyLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDCENCREIDegrfp 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 110 -------VVRNKIKMFAQQKVTLP----KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQS 178
Cdd:PRK14958 89 dlfevdaASRTKVEDTRELLDNIPyaptKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHKLPVTVLS 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 179 RCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNL-QSTFSGFGYINSENVFKVCDEPHPLL 257
Cdd:PRK14958 169 RCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLdQSIAYGNGKVLIADVKTMLGTIEPLL 248
|
....*.
gi 55926133 258 VKEMIQ 263
Cdd:PRK14958 249 LFDILE 254
|
|
| PRK05564 |
PRK05564 |
DNA polymerase III subunit delta'; Validated |
41-220 |
3.00e-09 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180132 [Multi-domain] Cd Length: 313 Bit Score: 57.35 E-value: 3.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 41 KLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKttSILC--LARALLG-PALKDAV--LELNASNDR--GIDVVR 112
Cdd:PRK05564 2 SFHTIIGHENIKNRIKNSIIKNRFSHaHIIVGEDGIGK--SLLAkeIALKILGkSQQREYVdiIEFKPINKKsiGVDDIR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 113 NKIKMFAQQKVtlpKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQ 192
Cdd:PRK05564 80 NIIEEVNKKPY---EGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYKLNRLSKEE 156
|
170 180
....*....|....*....|....*...
gi 55926133 193 VLSRLMNvieKEKVPYTDDGLEAIIFTA 220
Cdd:PRK05564 157 IEKFISY---KYNDIKEEEKKSAIAFSD 181
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
30-232 |
5.53e-09 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 57.37 E-value: 5.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 30 ELPWVEKYRPVKLNEIVGN-----EDTVSRLEVFAreGNVPNIIIAGPPGTGKTTsilcLARaLLGPALKDAVLELNASN 104
Cdd:PRK13341 15 EAPLADRLRPRTLEEFVGQdhilgEGRLLRRAIKA--DRVGSLILYGPPGVGKTT----LAR-IIANHTRAHFSSLNAVL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 105 dRGIDVVRNKIKMfAQQKVtlpkGRH---KIIILDEADSMTDGAQQAL-----RRTMEIYSKTTRfalacNASDKIIEPI 176
Cdd:PRK13341 88 -AGVKDLRAEVDR-AKERL----ERHgkrTILFIDEVHRFNKAQQDALlpwveNGTITLIGATTE-----NPYFEVNKAL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 55926133 177 QSRCAVLRYTKLTDA---QVLSRLMNVIE----KEKVPYTDDGLEAIIFTAQGDMRQALNNLQ 232
Cdd:PRK13341 157 VSRSRLFRLKSLSDEdlhQLLKRALQDKErgygDRKVDLEPEAEKHLVDVANGDARSLLNALE 219
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
47-189 |
7.83e-09 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 54.14 E-value: 7.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 47 GNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARALLGPALKDA-----------VLELNASNDRGIDVVRNK 114
Cdd:pfam13177 1 GQPEAIQLLQNSLENGRLSHaYLFSGPEGVGKLELALAFAKALFCEEPGDDlpcgqcrscrrIESGNHPDLVIIEPEGQS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 115 IKM----FAQQKVTLP--KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKL 188
Cdd:pfam13177 81 IKIdqirELQKEFSKSpyEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPL 160
|
.
gi 55926133 189 T 189
Cdd:pfam13177 161 S 161
|
|
| PRK14952 |
PRK14952 |
DNA polymerase III subunits gamma/tau; |
36-237 |
9.29e-09 |
|
DNA polymerase III subunits gamma/tau;
Pssm-ID: 237866 [Multi-domain] Cd Length: 584 Bit Score: 56.81 E-value: 9.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARAL-------------------LGPALKD 95
Cdd:PRK14952 6 KYRPATFAEVVGQEHVTEPLSSALDAGRINHAyLFSGPRGCGKTSSARILARSLncaqgptatpcgvcescvaLAPNGPG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 96 A--VLELNASNDRGIDVVRNkikmFAQQKVTLP-KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKI 172
Cdd:PRK14952 86 SidVVELDAASHGGVDDTRE----LRDRAFYAPaQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKV 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 55926133 173 IEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSG 237
Cdd:PRK14952 162 LPTIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLLAG 226
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
36-228 |
1.85e-08 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 56.01 E-value: 1.85e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 36 KYRPVKLNEIVGNEDTVSRLeVFAREGNVPN--IIIAGPPGTGKTTSILCLARAL------------LGPALK------- 94
Cdd:PRK07003 9 KWRPKDFASLVGQEHVVRAL-THALDGGRLHhaYLFTGTRGVGKTTLSRIFAKALncetgvtsqpcgVCRACReidegrf 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 95 -DAVlELNASNDRGIDvvrnkiKMFA--QQKVTLP-KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASD 170
Cdd:PRK07003 88 vDYV-EMDAASNRGVD------EMAAllERAVYAPvDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 55926133 171 KIIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQAL 228
Cdd:PRK07003 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDAL 218
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
67-165 |
2.52e-07 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 48.88 E-value: 2.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 67 IIIAGPPGTGKTTSILCLARALlgPALKDAVLELNASNDRGIDVVRNKI-------KMFAQQKVTLPK---------GRH 130
Cdd:pfam13401 8 LVLTGESGTGKTTLLRRLLEQL--PEVRDSVVFVDLPSGTSPKDLLRALlralglpLSGRLSKEELLAalqqlllalAVA 85
|
90 100 110
....*....|....*....|....*....|....*
gi 55926133 131 KIIILDEADSMTDGAQQALRRTMEIYSKTTRFALA 165
Cdd:pfam13401 86 VVLIIDEAQHLSLEALEELRDLLNLSSKLLQLILV 120
|
|
| PRK06871 |
PRK06871 |
DNA polymerase III subunit delta'; Validated |
105-182 |
4.14e-07 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180738 [Multi-domain] Cd Length: 325 Bit Score: 50.89 E-value: 4.14e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 105 DRGIDVVRN---KIKMFAQQkvtlpkGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCA 181
Cdd:PRK06871 86 DIGVDQVREineKVSQHAQQ------GGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQ 159
|
.
gi 55926133 182 V 182
Cdd:PRK06871 160 T 160
|
|
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
32-232 |
4.45e-07 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 51.50 E-value: 4.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 32 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-----IIIAGPPGTGKTTSILCLARaLLGPALKDAVLELN---AS 103
Cdd:TIGR00602 73 PWVEKYKPETQHELAVHKKKIEEVETWLKAQVLENapkriLLITGPSGCGKSTTIKILSK-ELGIQVQEWSNPTLpdfQK 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 104 ND-RGIDVVRNKIKMFAQQKVTLP-----------------KGRHKIIILDEADSMTDGAQQALRRTME-IYSKTTRFAL 164
Cdd:TIGR00602 152 NDhKVTLSLESCFSNFQSQIEVFSefllratnklqmlgddlMTDKKIILVEDLPNQFYRDTRALHEILRwKYVSIGRCPL 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 165 AC-----------------NASDKIIEPIQSRCAVLRYT-KLTDAQVLSRLMNVI---------EKEKVPYTDDgLEAII 217
Cdd:TIGR00602 232 VFiiteslegdnnqrrllfPAETIMNKEILEEPRVSNISfNPIAPTIMKKFLNRIvtieakkngEKIKVPKKTS-VELLC 310
|
250
....*....|....*
gi 55926133 218 FTAQGDMRQALNNLQ 232
Cdd:TIGR00602 311 QGCSGDIRSAINSLQ 325
|
|
| HLD_clamp |
cd18133 |
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ... |
191-233 |
1.00e-06 |
|
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.
Pssm-ID: 350838 [Multi-domain] Cd Length: 65 Bit Score: 45.54 E-value: 1.00e-06
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 55926133 191 AQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQS 233
Cdd:cd18133 4 EQLKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQR 46
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
29-227 |
2.23e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 49.19 E-value: 2.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 29 YElPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNV-PNIIIAGPPGTGKTTSILCLARAL------------------- 88
Cdd:PRK14948 3 YE-PLHHKYRPQRFDELVGQEAIATTLKNALISNRIaPAYLFTGPRGTGKTSSARILAKSLnclnsdkptpepcgkcelc 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 89 ----LGPALkDaVLELNASNDRGIDVVRNKIK--MFAqqkvtlP-KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTR 161
Cdd:PRK14948 82 raiaAGNAL-D-VIEIDAASNTGVDNIRELIEraQFA------PvQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVV 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 55926133 162 FALACNASDKIIEPIQSRCAVLRYTKLT-DAQVlSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQA 227
Cdd:PRK14948 154 FVLATTDPQRVLPTIISRCQRFDFRRIPlEAMV-QHLSEIAEKESIEIEPEALTLVAQRSQGGLRDA 219
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
42-154 |
7.14e-06 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 46.80 E-value: 7.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 42 LNEIVGNEDTVSRLEVFARE----------GNVP--NIIIAGPPGTGKTTsilcLARALLGpALKDAVLELNASndrGI- 108
Cdd:COG1223 1 LDDVVGQEEAKKKLKLIIKElrrrenlrkfGLWPprKILFYGPPGTGKTM----LAEALAG-ELKLPLLTVRLD---SLi 72
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 55926133 109 -----DVVRNKIKMFAQQKvtlpkgRHK-IIILDEADSMtdgaqqALRRTME 154
Cdd:COG1223 73 gsylgETARNLRKLFDFAR------RAPcVIFFDEFDAI------AKDRGDQ 112
|
|
| McrB |
COG1401 |
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB ... |
17-91 |
2.09e-05 |
|
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB [Defense mechanisms];
Pssm-ID: 441011 [Multi-domain] Cd Length: 477 Bit Score: 46.30 E-value: 2.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 17 EPSPVPSKTTGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNV----------PNIIIAGPPGTGKTTSILCLAR 86
Cdd:COG1401 164 ELLAAPEDLSADALAAELSAAEELYSEDLESEDDYLKDLLREKFEETLeaflaalktkKNVILAGPPGTGKTYLARRLAE 243
|
....*
gi 55926133 87 ALLGP 91
Cdd:COG1401 244 ALGGE 248
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
60-154 |
2.26e-05 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 45.66 E-value: 2.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 60 REGNVpnIIIAGPPGTGKTTSILCLARA------LLG-PALKDAVLELNASNDRGiDVVRNKIKMFAQQKVTLPKGRHKI 132
Cdd:COG3598 11 PEGGV--TLLAGPPGTGKSFLALQLAAAvaaggpWLGrRVPPGKVLYLAAEDDRG-ELRRRLKALGADLGLPFADLDGRL 87
|
90 100
....*....|....*....|...
gi 55926133 133 IILDEADSMTD-GAQQALRRTME 154
Cdd:COG3598 88 RLLSLAGDLDDtDDLEALERAIE 110
|
|
| DEXXQc_Upf1-like |
cd17934 |
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, ... |
68-138 |
3.10e-05 |
|
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, HELZ, Mov10L1, Aquarius, IGHMBP2 (SMUBP2), coronavirus Nsp13, and similar proteins. They belong to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438708 [Multi-domain] Cd Length: 121 Bit Score: 42.99 E-value: 3.10e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 55926133 68 IIAGPPGTGKTTSILCLARALLGPALKDAVLeLNASNDRGIDVVRnkikmfaqqkvtlpkgrhkIIILDEA 138
Cdd:cd17934 3 LIQGPPGTGKTTTIAAIVLQLLKGLRGKRVL-VTAQSNVAVDNVD-------------------VVIIDEA 53
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
34-140 |
3.39e-05 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 45.29 E-value: 3.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 34 VEKYRPVKLNEIVGNEDTVSRL-----------EVFAREGNVP--NIIIAGPPGTGKTTSILCLARALLGPalkdaVLEL 100
Cdd:COG0464 148 LLELREAILDDLGGLEEVKEELrelvalplkrpELREEYGLPPprGLLLYGPPGTGKTLLARALAGELGLP-----LIEV 222
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 55926133 101 NASNDRGIDV------VRnkiKMFAQQKVTLPkGrhkIIILDEADS 140
Cdd:COG0464 223 DLSDLVSKYVgeteknLR---EVFDKARGLAP-C---VLFIDEADA 261
|
|
| ruvB |
PRK00080 |
Holliday junction branch migration DNA helicase RuvB; |
38-79 |
6.14e-05 |
|
Holliday junction branch migration DNA helicase RuvB;
Pssm-ID: 234619 [Multi-domain] Cd Length: 328 Bit Score: 44.35 E-value: 6.14e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 55926133 38 RPVKLNEIVGNEDTVSRLEVF---AREGNVP--NIIIAGPPGTGKTT 79
Cdd:PRK00080 20 RPKSLDEFIGQEKVKENLKIFieaAKKRGEAldHVLLYGPPGLGKTT 66
|
|
| Rad17 |
pfam03215 |
Rad17 P-loop domain; |
32-95 |
6.88e-05 |
|
Rad17 P-loop domain;
Pssm-ID: 367398 [Multi-domain] Cd Length: 186 Bit Score: 43.02 E-value: 6.88e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 55926133 32 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-----IIIAGPPGTGKTTSILCLARaLLGPALKD 95
Cdd:pfam03215 8 QWYEKYKPNCLEQLAVHKRKIKDVQEWLDAMFLENakhriLLISGPSGCGKSTVIKELSK-ELGPKYRE 75
|
|
| RuvB_N |
pfam05496 |
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ... |
38-93 |
7.21e-05 |
|
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.
Pssm-ID: 398900 [Multi-domain] Cd Length: 159 Bit Score: 42.49 E-value: 7.21e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 55926133 38 RPVKLNEIVGNEDTVSRLEVF---AREGNVP--NIIIAGPPGTGKTTSILCLARAL-------LGPAL 93
Cdd:pfam05496 2 RPRTLDEYIGQEKVKENLKIFieaAKQRGEAldHVLLYGPPGLGKTTLANIIANEMgvniritSGPAI 69
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
42-173 |
1.03e-04 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 42.23 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 42 LNEIVGNEDTVSRLEVFAREGNVpnIIIAGPPGTGKTTSILCLARaLLGPALKDAVLELNASNDRGIDVVRNKIKMFAQ- 120
Cdd:cd00267 5 LSFRYGGRTALDNVSLTLKAGEI--VALVGPNGSGKSTLLRAIAG-LLKPTSGEILIDGKDIAKLPLEELRRRIGYVPQl 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 121 -----QKVTLPK---GRHKIIILDEADSMTDGA-QQALRRTMEIYSKTTR--------FALACNASDKII 173
Cdd:cd00267 82 sggqrQRVALARallLNPDLLLLDEPTSGLDPAsRERLLELLRELAEEGRtviivthdPELAELAADRVI 151
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
37-231 |
1.13e-04 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 43.68 E-value: 1.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 37 YRPvklNEIVGNEDTVSR----LEVFAREGNVPNIIIAGPPGTGKTTSILCLARAL----------LGPA---------- 92
Cdd:COG1474 23 YVP---DRLPHREEEIEElasaLRPALRGERPSNVLIYGPTGTGKTAVAKYVLEELeeeaeergvdVRVVyvncrqastr 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 93 ---LKDAVLELNASND---RGI--DVVRNKIKmfaqqKVTLPKGRHKIIILDEADSMTDGAQQ----ALRRTMEIYSKtT 160
Cdd:COG1474 100 yrvLSRILEELGSGEDipsTGLstDELFDRLY-----EALDERDGVLVVVLDEIDYLVDDEGDdllyQLLRANEELEG-A 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 161 RFALACNASDkiiepiqsrcavLRYTKLTDAQVLSRLMnvieKEKV---PYTDDGLEAII-------------------- 217
Cdd:COG1474 174 RVGVIGISND------------LEFLENLDPRVKSSLG----EEEIvfpPYDADELRDILedraelafydgvlsdevipl 237
|
250
....*....|....*....
gi 55926133 218 ---FTAQ--GDMRQALNNL 231
Cdd:COG1474 238 iaaLAAQehGDARKAIDLL 256
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
41-141 |
2.24e-04 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 41.11 E-value: 2.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 41 KLNEIVGNEDTVSRLEVFaREGNVPNIIIAGPPGTGKTTSILCLARALLGPALkdaVLELNASNDRGIDVVRNKI-KMFA 119
Cdd:cd19481 4 SLREAVEAPRRGSRLRRY-GLGLPKGILLYGPPGTGKTLLAKALAGELGLPLI---VVKLSSLLSKYVGESEKNLrKIFE 79
|
90 100
....*....|....*....|..
gi 55926133 120 QqkvtLPKGRHKIIILDEADSM 141
Cdd:cd19481 80 R----ARRLAPCILFIDEIDAI 97
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
4-153 |
2.73e-04 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 42.30 E-value: 2.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 4 QESGSGSAESGTQEPSPVPSKTTGHYELPWVEKYRP-VKLNEIVGNEDTVSRL-----------EVFAREGNVP--NIII 69
Cdd:COG1222 38 ALELLEEAPALLLNDANLTQKRLGTPRGTAVPAESPdVTFDDIGGLDEQIEEIreavelplknpELFRKYGIEPpkGVLL 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 70 AGPPGTGKTTsilcLARALLGpalkdavlELNAS--NDRGIDVV--------RNKIKMFAQQKvtlpKGRHKIIILDEAD 139
Cdd:COG1222 118 YGPPGTGKTL----LAKAVAG--------ELGAPfiRVRGSELVskyigegaRNVREVFELAR----EKAPSIIFIDEID 181
|
170
....*....|....*....
gi 55926133 140 SM----TDGAQ-QALRRTM 153
Cdd:COG1222 182 AIaarrTDDGTsGEVQRTV 200
|
|
| RuvB |
COG2255 |
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ... |
38-79 |
3.24e-04 |
|
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];
Pssm-ID: 441856 [Multi-domain] Cd Length: 337 Bit Score: 41.99 E-value: 3.24e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 55926133 38 RPVKLNEIVGNEDTVSRLEVF---AREGNVP--NIIIAGPPGTGKTT 79
Cdd:COG2255 23 RPKRLDEYIGQEKVKENLKIFieaAKKRGEAldHVLLYGPPGLGKTT 69
|
|
| PRK07940 |
PRK07940 |
DNA polymerase III subunit delta'; Validated |
69-180 |
3.38e-04 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236134 [Multi-domain] Cd Length: 394 Bit Score: 42.21 E-value: 3.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 69 IAGPPGTGKTTSILCLARALLGPALKD----------AVLELNASNDR---------GIDVVRNKIKMFAQQKVTlpkGR 129
Cdd:PRK07940 41 FTGPPGSGRSVAARAFAAALQCTDPDEpgcgecracrTVLAGTHPDVRvvapeglsiGVDEVRELVTIAARRPST---GR 117
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 55926133 130 HKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRC 180
Cdd:PRK07940 118 WRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVLPTIRSRC 168
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
44-90 |
4.37e-04 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 40.56 E-value: 4.37e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 55926133 44 EIVGNEDTVSRLEVF---AREGNVPNIIIAGPPGTGKTTSILCLARALLG 90
Cdd:pfam13191 1 RLVGREEELEQLLDAldrVRSGRPPSVLLTGEAGTGKTTLLRELLRALER 50
|
|
| DEXXQc_SF1 |
cd18043 |
DEXXQ-box helicase domain of Superfamily 1 helicases; Superfamily 1 (SF1) helicases are ... |
53-141 |
6.40e-04 |
|
DEXXQ-box helicase domain of Superfamily 1 helicases; Superfamily 1 (SF1) helicases are nucleic acid motor proteins that couple ATP hydrolysis to translocation along with the concomitant unwinding of DNA or RNA. This is central to many aspects of cellular DNA and RNA metabolism and accordingly, they are implicated in a wide range of nucleic acid processing events including DNA replication, recombination, and repair as well as many aspects of RNA metabolism. Superfamily 1 helicases are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350801 [Multi-domain] Cd Length: 127 Bit Score: 39.10 E-value: 6.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 53 SRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLgpALKDAVLeLNASNDRGIDVVRNKIKMFAQQKV--TLPKGRH 130
Cdd:cd18043 3 SQEAAIISARNGKNVVIQGPPGTGKSQTIANIIANAL--ARGKRVL-FVSEKKAALDVVRFPCWIMSPLSVsqYLPLNRN 79
|
90
....*....|...
gi 55926133 131 K--IIILDEADSM 141
Cdd:cd18043 80 LfdLVIFDEASQI 92
|
|
| DEXSc_RecD-like |
cd17933 |
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ... |
65-143 |
6.54e-04 |
|
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350691 [Multi-domain] Cd Length: 155 Bit Score: 39.85 E-value: 6.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 65 PNIIIAGPPGTGKTTSILCLARA---------LLGPALKdAVLELnaSNDRGIDVV-------RNKIKMFAQQKVTlPKG 128
Cdd:cd17933 13 RVSVLTGGAGTGKTTTLKALLAAleaegkrvvLAAPTGK-AAKRL--SESTGIEAStihrllgINPGGGGFYYNEE-NPL 88
|
90
....*....|....*
gi 55926133 129 RHKIIILDEAdSMTD 143
Cdd:cd17933 89 DADLLIVDEA-SMVD 102
|
|
| Viral_helicase1 |
pfam01443 |
Viral (Superfamily 1) RNA helicase; Helicase activity for this family has been demonstrated ... |
67-138 |
8.36e-04 |
|
Viral (Superfamily 1) RNA helicase; Helicase activity for this family has been demonstrated and NTPase activity. This helicase has multiple roles at different stages of viral RNA replication, as dissected by mutational analysis.
Pssm-ID: 366646 [Multi-domain] Cd Length: 227 Bit Score: 40.44 E-value: 8.36e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 55926133 67 IIIAGPPGTGKTTSILCLARALLG--PALKDAvlelnasNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEA 138
Cdd:pfam01443 1 IVVHGVPGCGKSTLIRKLLRTSRVirPTAELR-------TEGKPDLPNLNVRTVDTFLMALLKPTGKILILDEY 67
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
192-232 |
1.34e-03 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 36.84 E-value: 1.34e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 55926133 192 QVLSRLMNVIE---KEKVPYTDDGLEAIIFTAQGDMRQALNNLQ 232
Cdd:cd18139 8 KLLKRALEDKErggDRKVTIDDEALELLAEAADGDARSALNLLE 51
|
|
| PRK06090 |
PRK06090 |
DNA polymerase III subunit delta'; Validated |
119-180 |
1.44e-03 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180394 [Multi-domain] Cd Length: 319 Bit Score: 40.17 E-value: 1.44e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 55926133 119 AQQKVTLpkGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRC 180
Cdd:PRK06090 100 AQESSQL--NGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRC 159
|
|
| Mg_chelatase |
pfam01078 |
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ... |
42-104 |
1.51e-03 |
|
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.
Pssm-ID: 426032 [Multi-domain] Cd Length: 207 Bit Score: 39.44 E-value: 1.51e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 55926133 42 LNEIVGNEDTVSRLEVFAREGNvpNIIIAGPPGTGKTTsilcLARALLG--PALKDA-VLELNASN 104
Cdd:pfam01078 2 LADVKGQEQAKRALEIAAAGGH--NLLMIGPPGSGKTM----LAKRLPGilPPLTEAeALEVTAIH 61
|
|
| DEXXQc_SETX |
cd18042 |
DEXXQ-box helicase domain of SETX; The RNA/DNA helicase senataxin (SETX) plays a role in ... |
63-116 |
2.45e-03 |
|
DEXXQ-box helicase domain of SETX; The RNA/DNA helicase senataxin (SETX) plays a role in transcription, neurogenesis, and antiviral response. SEXT is an R-loop-associated protein that is thought to function as an RNA/DNA helicase. R-loops consist of RNA/DNA hybrids, formed during transcription when nascent RNA hybridizes to the DNA template strand, displacing the non-template DNA strand. Mutations in SETX are linked to two neurodegenerative disorders: ataxia with oculomotor apraxia type 2 (AOA2) and amyotrophic lateral sclerosis type 4 (ALS4). S. cerevisiae homolog splicing endonuclease 1 (Sen1) is an exclusively nuclear protein, important for nucleolar organization. S. cerevisiae Sen1 and its ortholog, the Schizosaccharomyces pombe Sen1, share conserved domains and belong to the family I class of helicases. Both proteins translocate 5' to 3' and unwind both DNA and RNA duplexes and also RNA/DNA hybrids in vitro. SETX is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438712 [Multi-domain] Cd Length: 218 Bit Score: 38.73 E-value: 2.45e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 55926133 63 NVPNI-IIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIK 116
Cdd:cd18042 15 NSPGItLIQGPPGTGKTKTIVGILSVLLAGKYRKYYEKVKKKLRKLQRNLNNKKK 69
|
|
| DEXXQc_DNA2 |
cd18041 |
DEXXQ-box helicase domain of DNA2; DNA2 (DNA Replication Helicase/Nuclease 2) possesses ... |
68-98 |
3.57e-03 |
|
DEXXQ-box helicase domain of DNA2; DNA2 (DNA Replication Helicase/Nuclease 2) possesses different enzymatic activities, such as single-stranded DNA (ssDNA)-dependent ATPase, 5-3 helicase, and endonuclease activities, and is involved in DNA replication and DNA repair in the nucleus and mitochondrion. It is involved in Okazaki fragment processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. It is also involved in 5-end resection of DNA during double-strand break (DSB) repair; it is recruited by BLM and mediates the cleavage of 5-ssDNA, while the 3-ssDNA cleavage is prevented by the presence of RPA. DNA2 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350799 [Multi-domain] Cd Length: 203 Bit Score: 37.99 E-value: 3.57e-03
10 20 30
....*....|....*....|....*....|.
gi 55926133 68 IIAGPPGTGKTTSILCLARALLgpALKDAVL 98
Cdd:cd18041 21 LILGMPGTGKTTTIAALVRILV--ALGKSVL 49
|
|
| HypB |
COG0378 |
Hydrogenase/urease maturation factor HypB, Ni2+-binding GTPase [Posttranslational modification, ... |
60-99 |
3.70e-03 |
|
Hydrogenase/urease maturation factor HypB, Ni2+-binding GTPase [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440147 [Multi-domain] Cd Length: 200 Bit Score: 38.12 E-value: 3.70e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 55926133 60 REGNVPNIIIAGPPGTGKTTSILCLARAlLGPALKDAVLE 99
Cdd:COG0378 9 AEKGVLAVNLMGSPGSGKTTLLEKTIRA-LKDRLRIAVIE 47
|
|
| AAA_11 |
pfam13086 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
68-96 |
4.08e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.
Pssm-ID: 404072 [Multi-domain] Cd Length: 248 Bit Score: 38.48 E-value: 4.08e-03
10 20
....*....|....*....|....*....
gi 55926133 68 IIAGPPGTGKTTSILCLARALLGPALKDA 96
Cdd:pfam13086 17 LIQGPPGTGKTTTIVELIRQLLSYPATSA 45
|
|
| VirB11-like_ATPase |
cd01130 |
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, ... |
66-90 |
5.88e-03 |
|
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir (virulence) proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the bacterial Ti (tumor-inducing)-plasmid into plant cells. The pilus is a fibrous cell surface organelle, which mediates adhesion between bacteria during conjugative transfer or between bacteria and host eukaryotic cells during infection. VirB11-related ATPases include Sulfolobus acidocaldarius FlaI, which plays key roles in archaellum (archaeal flagellum) assembly and motility functions, and the pilus assembly proteins CpaF/TadA and TrbB. This alignment contains the C-terminal domain, which is the ATPase.
Pssm-ID: 410874 [Multi-domain] Cd Length: 177 Bit Score: 37.13 E-value: 5.88e-03
10 20
....*....|....*....|....*
gi 55926133 66 NIIIAGPPGTGKTTsilcLARALLG 90
Cdd:cd01130 14 NILISGGTGSGKTT----LLNALLS 34
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
65-143 |
7.05e-03 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 38.03 E-value: 7.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55926133 65 PNIIIAGPPGTGKTTSILCLARALLGPALKDAVL------ELNASNDRGIDVV--------RNKIKMFAQQKVTlPKGRH 130
Cdd:COG0507 141 RVSVLTGGAGTGKTTTLRALLAALEALGLRVALAaptgkaAKRLSESTGIEARtihrllglRPDSGRFRHNRDN-PLTPA 219
|
90
....*....|...
gi 55926133 131 KIIILDEAdSMTD 143
Cdd:COG0507 220 DLLVVDEA-SMVD 231
|
|
| |
