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Conserved domains on  [gi|14149647|ref|NP_035422|]
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large ribosomal subunit protein uL6 [Mus musculus]

Protein Classification

large ribosomal subunit protein uL6( domain architecture ID 1903905)

large ribosomal subunit protein uL6 is a component of the large ribosomal subunit

CATH:  3.90.930.12
Gene Ontology:  GO:0003735|GO:0003723|GO:0006412
PubMed:  11114498

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
PTZ00027 super family cl44316
60S ribosomal protein L6; Provisional
1-191 2.28e-81

60S ribosomal protein L6; Provisional


The actual alignment was detected with superfamily member PTZ00027:

Pssm-ID: 240234 [Multi-domain]  Cd Length: 190  Bit Score: 239.67  E-value: 2.28e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647    1 MKTILSNQTVDIPENVEITLKGRTVIVKGPRGTLRRDFNHINVELSLlGKKKKRLRVDKWWGNRKELATVRTICSHVQNM 80
Cdd:PTZ00027   1 MKTIFSSEKIRIPEGVTVTVKSRKVTVTGKYGELTRSFRHLPVDIKL-SKDGKYIKVEMWFGTPSHLACIRTVCSHIKNM 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647   81 IKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAAL 160
Cdd:PTZ00027  80 MTGVTKKFQYKMRLVYAHFPINSNITDNGKTIEIRNFLGEKRVRTVKMLPGVVVEKSESVKDEIIVTGADLELVSRSAAL 159
                        170       180       190
                 ....*....|....*....|....*....|.
gi 14149647  161 IQQATTVKNKDIRKFLDGIYVSEKGTVQQAD 191
Cdd:PTZ00027 160 IHQSTLVRNKDIRKFLDGIYVSEKGTVDKDE 190
 
Name Accession Description Interval E-value
PTZ00027 PTZ00027
60S ribosomal protein L6; Provisional
1-191 2.28e-81

60S ribosomal protein L6; Provisional


Pssm-ID: 240234 [Multi-domain]  Cd Length: 190  Bit Score: 239.67  E-value: 2.28e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647    1 MKTILSNQTVDIPENVEITLKGRTVIVKGPRGTLRRDFNHINVELSLlGKKKKRLRVDKWWGNRKELATVRTICSHVQNM 80
Cdd:PTZ00027   1 MKTIFSSEKIRIPEGVTVTVKSRKVTVTGKYGELTRSFRHLPVDIKL-SKDGKYIKVEMWFGTPSHLACIRTVCSHIKNM 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647   81 IKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAAL 160
Cdd:PTZ00027  80 MTGVTKKFQYKMRLVYAHFPINSNITDNGKTIEIRNFLGEKRVRTVKMLPGVVVEKSESVKDEIIVTGADLELVSRSAAL 159
                        170       180       190
                 ....*....|....*....|....*....|.
gi 14149647  161 IQQATTVKNKDIRKFLDGIYVSEKGTVQQAD 191
Cdd:PTZ00027 160 IHQSTLVRNKDIRKFLDGIYVSEKGTVDKDE 190
uL6_arch TIGR03653
ribosomal protein uL6, archaeal form; Members of this protein family are the archaeal form ...
10-184 1.19e-58

ribosomal protein uL6, archaeal form; Members of this protein family are the archaeal form ofribosomal protein uL6 (previously L9 in yeast and human). The top-scoring proteins not selected by this model are eukaryotic cytosolic uL6. Bacterial ribosomal protein L6 scores lower and is described by a distinct model. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 274702 [Multi-domain]  Cd Length: 170  Bit Score: 181.33  E-value: 1.19e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647    10 VDIPENVEITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKkkrLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFR 89
Cdd:TIGR03653   4 IEIPEGVSVTIEGNIVTVKGPKGEVTREFWYPGIEISVEDGK---VVIETDFARKKDKAMVGTFRSHIKNMIKGVTEGFE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647    90 YKMRSVYAHFPINVVIQenGSLVEIRNFLGEKYIRRVRMRTGVACSVSQaqkDELILEGNDIELVSNSAALIQQATTVKN 169
Cdd:TIGR03653  81 YKMKVVYSHFPMQVKVE--GNKVIIENFLGEKAPRRAKILGGVKVKVKG---EEVIVEGIDKEDVGQTAANIEQATRIKG 155
                         170
                  ....*....|....*
gi 14149647   170 KDIRKFLDGIYVSEK 184
Cdd:TIGR03653 156 RDPRVFQDGIYIVEK 170
Ribosomal_L6 pfam00347
Ribosomal protein L6;
99-178 6.09e-16

Ribosomal protein L6;


Pssm-ID: 425625  Cd Length: 78  Bit Score: 69.19  E-value: 6.09e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647    99 FPINVVIQENGslVEIRNFLGEKYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDG 178
Cdd:pfam00347   1 IPVGVRVSLKG--VNLVLVKGPKGELTREIPPGVTVEVEGNKVTVIVVSGIDKEKVGQFAALIGTVRALIPNMGKGVTEG 78
RplF COG0097
Ribosomal protein L6P/L9E [Translation, ribosomal structure and biogenesis]; Ribosomal protein ...
10-92 1.22e-11

Ribosomal protein L6P/L9E [Translation, ribosomal structure and biogenesis]; Ribosomal protein L6P/L9E is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439867 [Multi-domain]  Cd Length: 177  Bit Score: 60.41  E-value: 1.22e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647  10 VDIPENVEITLKGRTVIVKGPRGTLRRDFNHiNVELSLLGKK--------KKRLRvdKWWGnrkelaTVRticSHVQNMI 81
Cdd:COG0097   8 IPIPAGVEVTIDGNTVTVKGPKGELSRTLHP-DVKVKVEDNKltvtrpsdSKEAR--ALHG------TTR---ALINNMV 75
                        90
                ....*....|.
gi 14149647  82 KGVTLGFRYKM 92
Cdd:COG0097  76 EGVTEGFEKKL 86
 
Name Accession Description Interval E-value
PTZ00027 PTZ00027
60S ribosomal protein L6; Provisional
1-191 2.28e-81

60S ribosomal protein L6; Provisional


Pssm-ID: 240234 [Multi-domain]  Cd Length: 190  Bit Score: 239.67  E-value: 2.28e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647    1 MKTILSNQTVDIPENVEITLKGRTVIVKGPRGTLRRDFNHINVELSLlGKKKKRLRVDKWWGNRKELATVRTICSHVQNM 80
Cdd:PTZ00027   1 MKTIFSSEKIRIPEGVTVTVKSRKVTVTGKYGELTRSFRHLPVDIKL-SKDGKYIKVEMWFGTPSHLACIRTVCSHIKNM 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647   81 IKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAAL 160
Cdd:PTZ00027  80 MTGVTKKFQYKMRLVYAHFPINSNITDNGKTIEIRNFLGEKRVRTVKMLPGVVVEKSESVKDEIIVTGADLELVSRSAAL 159
                        170       180       190
                 ....*....|....*....|....*....|.
gi 14149647  161 IQQATTVKNKDIRKFLDGIYVSEKGTVQQAD 191
Cdd:PTZ00027 160 IHQSTLVRNKDIRKFLDGIYVSEKGTVDKDE 190
rpl6p PRK05518
50S ribosomal protein L6P; Reviewed
1-185 4.68e-62

50S ribosomal protein L6P; Reviewed


Pssm-ID: 235496 [Multi-domain]  Cd Length: 180  Bit Score: 190.44  E-value: 4.68e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647    1 MKTILSNQTVDIPENVEITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKkkrLRVDKWWGNRKELATVRTICSHVQNM 80
Cdd:PRK05518   1 MVAAYIREEIEIPEGVTVEIEGLVVTVKGPKGELTRDFWYPGVTISVEDGK---VVIETEFARKKTKAMVGTFASHIKNM 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647   81 IKGVTLGFRYKMRSVYAHFPINVVIQenGSLVEIRNFLGEKYIRRVRMRTGVACSVSqaqKDELILEGNDIELVSNSAAL 160
Cdd:PRK05518  78 IKGVTEGFEYKLKIVYSHFPMQVKVQ--GNEVVIENFLGEKSPRRAKILGGVKVKVK---GEDVIVEGIDKEDVGQTAAN 152
                        170       180
                 ....*....|....*....|....*
gi 14149647  161 IQQATTVKNKDIRKFLDGIYVSEKG 185
Cdd:PRK05518 153 IEQATKIKGFDRRVFQDGIYIVEKE 177
uL6_arch TIGR03653
ribosomal protein uL6, archaeal form; Members of this protein family are the archaeal form ...
10-184 1.19e-58

ribosomal protein uL6, archaeal form; Members of this protein family are the archaeal form ofribosomal protein uL6 (previously L9 in yeast and human). The top-scoring proteins not selected by this model are eukaryotic cytosolic uL6. Bacterial ribosomal protein L6 scores lower and is described by a distinct model. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 274702 [Multi-domain]  Cd Length: 170  Bit Score: 181.33  E-value: 1.19e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647    10 VDIPENVEITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKkkrLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFR 89
Cdd:TIGR03653   4 IEIPEGVSVTIEGNIVTVKGPKGEVTREFWYPGIEISVEDGK---VVIETDFARKKDKAMVGTFRSHIKNMIKGVTEGFE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647    90 YKMRSVYAHFPINVVIQenGSLVEIRNFLGEKYIRRVRMRTGVACSVSQaqkDELILEGNDIELVSNSAALIQQATTVKN 169
Cdd:TIGR03653  81 YKMKVVYSHFPMQVKVE--GNKVIIENFLGEKAPRRAKILGGVKVKVKG---EEVIVEGIDKEDVGQTAANIEQATRIKG 155
                         170
                  ....*....|....*
gi 14149647   170 KDIRKFLDGIYVSEK 184
Cdd:TIGR03653 156 RDPRVFQDGIYIVEK 170
PTZ00179 PTZ00179
60S ribosomal protein L9; Provisional
4-191 2.87e-58

60S ribosomal protein L9; Provisional


Pssm-ID: 140206 [Multi-domain]  Cd Length: 189  Bit Score: 180.90  E-value: 2.87e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647    4 ILSNQTVDIPENVEITLKGRTVIVKGPRGTLRRDFNHINVELSLlGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKG 83
Cdd:PTZ00179   3 IKSQDTITIPEDVTVSVKDRIVTVKGKRGTLTKDLRHLQLDFRV-NKKNRTFTAVRWFGSKIPNSTINTALSHVRNMITG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647   84 VTLGFRYKMRSVYAHFPINVVIQenGSLVEIRNFLGEKYIRRVRMRTGVACSVSQAQ--KDELILEGNDIELVSNSAALI 161
Cdd:PTZ00179  82 VTKGFRFKVRFAYAHFPISVSVE--NQLVEIRNFLGEKRVRRQVVADTVKVYRTDPSkvKDELVLEGNDLEQVSREAAVM 159
                        170       180       190
                 ....*....|....*....|....*....|
gi 14149647  162 QQATTVKNKDIRKFLDGIYVSEKGTVQQAD 191
Cdd:PTZ00179 160 HQLCLVKKKDIRKFLDGIYVQTKTNVEAEE 189
Ribosomal_L6 pfam00347
Ribosomal protein L6;
99-178 6.09e-16

Ribosomal protein L6;


Pssm-ID: 425625  Cd Length: 78  Bit Score: 69.19  E-value: 6.09e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647    99 FPINVVIQENGslVEIRNFLGEKYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDG 178
Cdd:pfam00347   1 IPVGVRVSLKG--VNLVLVKGPKGELTREIPPGVTVEVEGNKVTVIVVSGIDKEKVGQFAALIGTVRALIPNMGKGVTEG 78
RplF COG0097
Ribosomal protein L6P/L9E [Translation, ribosomal structure and biogenesis]; Ribosomal protein ...
10-92 1.22e-11

Ribosomal protein L6P/L9E [Translation, ribosomal structure and biogenesis]; Ribosomal protein L6P/L9E is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439867 [Multi-domain]  Cd Length: 177  Bit Score: 60.41  E-value: 1.22e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647  10 VDIPENVEITLKGRTVIVKGPRGTLRRDFNHiNVELSLLGKK--------KKRLRvdKWWGnrkelaTVRticSHVQNMI 81
Cdd:COG0097   8 IPIPAGVEVTIDGNTVTVKGPKGELSRTLHP-DVKVKVEDNKltvtrpsdSKEAR--ALHG------TTR---ALINNMV 75
                        90
                ....*....|.
gi 14149647  82 KGVTLGFRYKM 92
Cdd:COG0097  76 EGVTEGFEKKL 86
Ribosomal_L6 pfam00347
Ribosomal protein L6;
12-87 2.09e-10

Ribosomal protein L6;


Pssm-ID: 425625  Cd Length: 78  Bit Score: 54.56  E-value: 2.09e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647    12 IPENVEITLKGRTVI-VKGPRGTLRRDFNHiNVELSLLGKKKKRLRVDkwwGNRKEL-----ATVRTICSHVQNMIKGVT 85
Cdd:pfam00347   1 IPVGVRVSLKGVNLVlVKGPKGELTREIPP-GVTVEVEGNKVTVIVVS---GIDKEKvgqfaALIGTVRALIPNMGKGVT 76

                  ..
gi 14149647    86 LG 87
Cdd:pfam00347  77 EG 78
rpl6 CHL00140
ribosomal protein L6; Validated
10-93 1.01e-07

ribosomal protein L6; Validated


Pssm-ID: 177062 [Multi-domain]  Cd Length: 178  Bit Score: 49.52  E-value: 1.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14149647   10 VDIPENVEITLKGRTVIVKGPRGTLRRDF----------NHINVELSLLGKKKKRLRvdkwwgnrkelATVRTIcshVQN 79
Cdd:CHL00140   9 IKIPDNVNVSIDDQIIKVKGPKGTLSRKIpdlitieiqdNSLFVSKKDESKKARALH-----------GLYRTL---INN 74
                         90
                 ....*....|....
gi 14149647   80 MIKGVTLGFRYKMR 93
Cdd:CHL00140  75 MVIGVSEGFEKKLE 88
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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