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Conserved domains on  [gi|2284291807|ref|NP_001397488|]
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sugar transporter SWEET1 isoform 6 precursor [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MtN3_slv pfam03083
Sugar efflux transporter for intercellular exchange; This family includes proteins such as ...
 9-95 2.58e-32

Sugar efflux transporter for intercellular exchange; This family includes proteins such as drosophila saliva, MtN3 involved in root nodule development and a protein involved in activation and expression of recombination activation genes (RAGs). Although the molecular function of these proteins is unknown, they are almost certainly transmembrane proteins. This family contains a region of two transmembrane helices that is found in two copies in most members of the family. This family also contains specific sugar efflux transporters that are essential for the maintenance of animal blood glucose levels, plant nectar production, and plant seed and pollen development. In many organizims it meditaes gluose transport; in Arabidopsis it is necessary for pollen viability; and two of the rice homologs are specifically exploited by bacterial pathogens for virulence by means of direct binding of a bacterial effector to the SWEET promoter.


:

Pssm-ID: 397278  Cd Length: 87  Bit Score: 109.59  E-value: 2.58e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2284291807   9 SFLSSACVLFTLGMFSTGLSDLRHMQRTRSVDNIQFLPFLTTDVNNLSWLSYGVLKGDGTLIIVNSVGAVLQTLYILAYL 88
Cdd:pfam03083   1 FLLGILCVVFTVAMFLSPLSILRKIIKTKSTEGMPFLPFLAGLLSASLWLLYGLLKKDGYIIIPNGIGCFLGTIYLILFI 80


                  ....*..
gi 2284291807  89 HYSPQKA 95
Cdd:pfam03083  81 VYPPKKA 87
MtN3_slv super family cl46784
Sugar efflux transporter for intercellular exchange; This family includes proteins such as ...
 95-134 1.18e-09

Sugar efflux transporter for intercellular exchange; This family includes proteins such as drosophila saliva, MtN3 involved in root nodule development and a protein involved in activation and expression of recombination activation genes (RAGs). Although the molecular function of these proteins is unknown, they are almost certainly transmembrane proteins. This family contains a region of two transmembrane helices that is found in two copies in most members of the family. This family also contains specific sugar efflux transporters that are essential for the maintenance of animal blood glucose levels, plant nectar production, and plant seed and pollen development. In many organizims it meditaes gluose transport; in Arabidopsis it is necessary for pollen viability; and two of the rice homologs are specifically exploited by bacterial pathogens for virulence by means of direct binding of a bacterial effector to the SWEET promoter.


The actual alignment was detected with superfamily member pfam03083:

Pssm-ID: 481124  Cd Length: 87  Bit Score: 51.43  E-value: 1.18e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2284291807  95 AKIVQTKSTQRLSFSLTIATLFCSASWSIYGFRLRDPYIT 134
Cdd:pfam03083  23 RKIIKTKSTEGMPFLPFLAGLLSASLWLLYGLLKKDGYII 62
 
Name Accession Description Interval E-value
MtN3_slv pfam03083
Sugar efflux transporter for intercellular exchange; This family includes proteins such as ...
 9-95 2.58e-32

Sugar efflux transporter for intercellular exchange; This family includes proteins such as drosophila saliva, MtN3 involved in root nodule development and a protein involved in activation and expression of recombination activation genes (RAGs). Although the molecular function of these proteins is unknown, they are almost certainly transmembrane proteins. This family contains a region of two transmembrane helices that is found in two copies in most members of the family. This family also contains specific sugar efflux transporters that are essential for the maintenance of animal blood glucose levels, plant nectar production, and plant seed and pollen development. In many organizims it meditaes gluose transport; in Arabidopsis it is necessary for pollen viability; and two of the rice homologs are specifically exploited by bacterial pathogens for virulence by means of direct binding of a bacterial effector to the SWEET promoter.


Pssm-ID: 397278  Cd Length: 87  Bit Score: 109.59  E-value: 2.58e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2284291807   9 SFLSSACVLFTLGMFSTGLSDLRHMQRTRSVDNIQFLPFLTTDVNNLSWLSYGVLKGDGTLIIVNSVGAVLQTLYILAYL 88
Cdd:pfam03083   1 FLLGILCVVFTVAMFLSPLSILRKIIKTKSTEGMPFLPFLAGLLSASLWLLYGLLKKDGYIIIPNGIGCFLGTIYLILFI 80


                  ....*..
gi 2284291807  89 HYSPQKA 95
Cdd:pfam03083  81 VYPPKKA 87
MtN3_slv pfam03083
Sugar efflux transporter for intercellular exchange; This family includes proteins such as ...
 95-134 1.18e-09

Sugar efflux transporter for intercellular exchange; This family includes proteins such as drosophila saliva, MtN3 involved in root nodule development and a protein involved in activation and expression of recombination activation genes (RAGs). Although the molecular function of these proteins is unknown, they are almost certainly transmembrane proteins. This family contains a region of two transmembrane helices that is found in two copies in most members of the family. This family also contains specific sugar efflux transporters that are essential for the maintenance of animal blood glucose levels, plant nectar production, and plant seed and pollen development. In many organizims it meditaes gluose transport; in Arabidopsis it is necessary for pollen viability; and two of the rice homologs are specifically exploited by bacterial pathogens for virulence by means of direct binding of a bacterial effector to the SWEET promoter.


Pssm-ID: 397278  Cd Length: 87  Bit Score: 51.43  E-value: 1.18e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2284291807  95 AKIVQTKSTQRLSFSLTIATLFCSASWSIYGFRLRDPYIT 134
Cdd:pfam03083  23 RKIIKTKSTEGMPFLPFLAGLLSASLWLLYGLLKKDGYII 62
SWEET COG4095
Sugar transporter, SemiSWEET family, contains PQ motif [Carbohydrate transport and metabolism]; ...
 30-87 1.73e-04

Sugar transporter, SemiSWEET family, contains PQ motif [Carbohydrate transport and metabolism];


Pssm-ID: 443271  Cd Length: 83  Bit Score: 37.86  E-value: 1.73e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2284291807  30 LRHMQRTRSVDNIQFLPFLTTDVNNLSWLSYGVLKGDGTLIIVNSVGAVLqTLYILAY 87
Cdd:COG4095    22 VIKTWKTKSTKDISLGMYLIFTTGVALWLIYGILIGDLPIILANAITLVL-ALIILVL 78
SWEET COG4095
Sugar transporter, SemiSWEET family, contains PQ motif [Carbohydrate transport and metabolism]; ...
 84-133 2.34e-04

Sugar transporter, SemiSWEET family, contains PQ motif [Carbohydrate transport and metabolism];


Pssm-ID: 443271  Cd Length: 83  Bit Score: 37.48  E-value: 2.34e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2284291807  84 ILAYLHYSPQKAKIVQTKSTQRLSFSLTIATLFCSASWSIYGFRLRDPYI 133
Cdd:COG4095    12 ILTTISFLPQVIKTWKTKSTKDISLGMYLIFTTGVALWLIYGILIGDLPI 61
 
Name Accession Description Interval E-value
MtN3_slv pfam03083
Sugar efflux transporter for intercellular exchange; This family includes proteins such as ...
 9-95 2.58e-32

Sugar efflux transporter for intercellular exchange; This family includes proteins such as drosophila saliva, MtN3 involved in root nodule development and a protein involved in activation and expression of recombination activation genes (RAGs). Although the molecular function of these proteins is unknown, they are almost certainly transmembrane proteins. This family contains a region of two transmembrane helices that is found in two copies in most members of the family. This family also contains specific sugar efflux transporters that are essential for the maintenance of animal blood glucose levels, plant nectar production, and plant seed and pollen development. In many organizims it meditaes gluose transport; in Arabidopsis it is necessary for pollen viability; and two of the rice homologs are specifically exploited by bacterial pathogens for virulence by means of direct binding of a bacterial effector to the SWEET promoter.


Pssm-ID: 397278  Cd Length: 87  Bit Score: 109.59  E-value: 2.58e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2284291807   9 SFLSSACVLFTLGMFSTGLSDLRHMQRTRSVDNIQFLPFLTTDVNNLSWLSYGVLKGDGTLIIVNSVGAVLQTLYILAYL 88
Cdd:pfam03083   1 FLLGILCVVFTVAMFLSPLSILRKIIKTKSTEGMPFLPFLAGLLSASLWLLYGLLKKDGYIIIPNGIGCFLGTIYLILFI 80


                  ....*..
gi 2284291807  89 HYSPQKA 95
Cdd:pfam03083  81 VYPPKKA 87
MtN3_slv pfam03083
Sugar efflux transporter for intercellular exchange; This family includes proteins such as ...
 95-134 1.18e-09

Sugar efflux transporter for intercellular exchange; This family includes proteins such as drosophila saliva, MtN3 involved in root nodule development and a protein involved in activation and expression of recombination activation genes (RAGs). Although the molecular function of these proteins is unknown, they are almost certainly transmembrane proteins. This family contains a region of two transmembrane helices that is found in two copies in most members of the family. This family also contains specific sugar efflux transporters that are essential for the maintenance of animal blood glucose levels, plant nectar production, and plant seed and pollen development. In many organizims it meditaes gluose transport; in Arabidopsis it is necessary for pollen viability; and two of the rice homologs are specifically exploited by bacterial pathogens for virulence by means of direct binding of a bacterial effector to the SWEET promoter.


Pssm-ID: 397278  Cd Length: 87  Bit Score: 51.43  E-value: 1.18e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2284291807  95 AKIVQTKSTQRLSFSLTIATLFCSASWSIYGFRLRDPYIT 134
Cdd:pfam03083  23 RKIIKTKSTEGMPFLPFLAGLLSASLWLLYGLLKKDGYII 62
SWEET COG4095
Sugar transporter, SemiSWEET family, contains PQ motif [Carbohydrate transport and metabolism]; ...
 30-87 1.73e-04

Sugar transporter, SemiSWEET family, contains PQ motif [Carbohydrate transport and metabolism];


Pssm-ID: 443271  Cd Length: 83  Bit Score: 37.86  E-value: 1.73e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2284291807  30 LRHMQRTRSVDNIQFLPFLTTDVNNLSWLSYGVLKGDGTLIIVNSVGAVLqTLYILAY 87
Cdd:COG4095    22 VIKTWKTKSTKDISLGMYLIFTTGVALWLIYGILIGDLPIILANAITLVL-ALIILVL 78
SWEET COG4095
Sugar transporter, SemiSWEET family, contains PQ motif [Carbohydrate transport and metabolism]; ...
 84-133 2.34e-04

Sugar transporter, SemiSWEET family, contains PQ motif [Carbohydrate transport and metabolism];


Pssm-ID: 443271  Cd Length: 83  Bit Score: 37.48  E-value: 2.34e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2284291807  84 ILAYLHYSPQKAKIVQTKSTQRLSFSLTIATLFCSASWSIYGFRLRDPYI 133
Cdd:COG4095    12 ILTTISFLPQVIKTWKTKSTKDISLGMYLIFTTGVALWLIYGILIGDLPI 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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