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Conserved domains on  [gi|2214681115|ref|NP_001390475|]
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nuclear mitotic apparatus protein 1 isoform a [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-151 1.26e-49

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


:

Pssm-ID: 411795  Cd Length: 148  Bit Score: 173.14  E-value: 1.26e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115    6 TRAATLLSWVNSLHVADPVETVLQLQDCSIFIKIINTIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2214681115   86 KVIEG--SEMELAKMIMLFLYQSTMSSRNlrDWEQFEYGVQAELAVILKFMLDHEESLNLTEDLESFL 151
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNL--TLEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFL 147
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 554-1323 1.40e-27

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 122.47  E-value: 1.40e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  554 LKLKEQQlEEAAKEQEATRQDHAQQLAIVAEAREA--SL-RERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT 630
Cdd:TIGR02168  168 SKYKERR-KETERKLERTRENLDRLEDILNELERQlkSLeRQAEKAERYKELKAELRELELALLVLRLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  631 SVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLkaeQQKTTEREKVVQEKAQLQEQLRALEESLKITKG 710
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL---YALANEISRLEQQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  711 SLEEEKRRaadaLKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHqaetEALRHELAEATASQ 790
Cdd:TIGR02168  324 QLEELESK----LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL----ETLRSKVAQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  791 HRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAK 870
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  871 AIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASlELLKEPPRAANRASDQLGEQQGRPFSST 950
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS-ELISVDEGYEAAIEAALGGRLQAVVVEN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  951 -HAAVKAMEREAEQMGG-----ELERLRAALIKSQGQQQEERGQQEREVA-RLTQERGQAQADL---------------A 1008
Cdd:TIGR02168  555 lNAAKKAIAFLKQNELGrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAkDLVKFDPKLRKALsyllggvlvvddldnA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1009 QEKAAKAELEMRLQnTLNEQRVE---FAALQEALAHALTekEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKE 1085
Cdd:TIGR02168  635 LELAKKLRPGYRIV-TLDGDLVRpggVITGGSAKTNSSI--LERRREIEELEEKIEELEEKIAELEKALAELRKELEELE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1086 KEHPAGGASGEDASgpGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQG 1165
Cdd:TIGR02168  712 EELEQLRKELEELS--RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1166 QLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESK 1245
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1246 ELKRLVVAESEKSQKLEERLRLL--QVETASNSARAAE-RSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELG 1322
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEY 949


                   .
gi 2214681115 1323 Q 1323
Cdd:TIGR02168  950 S 950
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1866-1924 4.54e-26

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


:

Pssm-ID: 412093  Cd Length: 56  Bit Score: 102.68  E-value: 4.54e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115 1866 LLSLPGYRPTTRSSARRSQarmSSGAPQGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1924
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1117-1652 1.53e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.79  E-value: 1.53e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1117 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1196
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1197 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVA-ESEKSQKLEERLRLLQ--VETA 1273
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEaEEELEELAEELLEALRaaAELA 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1274 SNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALV 1353
Cdd:COG1196    400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1354 SELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAEL--------------MRAQRELGELGSLRQKIVEQERAA 1419
Cdd:COG1196    480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagavavligveaaYEAALEAALAAALQNIVVEDDEVA 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1420 QQ----LRAEKASYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDqAREKYVQELAAVRTDAETHLAEMRQE 1493
Cdd:COG1196    560 AAaieyLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREAD-ARYYVLGDTLLGRTLVAARLEAALRR 638

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1494 AQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEvfqrEQTKQVEELSKKLTEHDQASKVQQQKLKAFQA 1573
Cdd:COG1196    639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE----ELAERLAEEELELEEALLAEEEEERELAEAEE 714

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115 1574 QRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKthydakkqqnqklQEQLQDLEELQKENKELRSEAERLG 1652
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE-------------LPEPPDLEELERELERLEREIEALG 780
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 213-814 2.22e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 98.86  E-value: 2.22e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  213 QMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALlnekqaassqepsELEELRGKNESLTVRLHE 292
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELAR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  293 TLKQCQNLKTEKSQMDRKISQLSEENgdlsfkvrefanhlqqlqgafndlieehskasQEWAEKQARLENELSTALQDKK 372
Cdd:COG1196    300 LEQDIARLEERRRELEERLEELEEEL--------------------------------AELEEELEELEEELEELEEELE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  373 CLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLEcergKQEAQLLAER 452
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL----ERLERLEEEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  453 SRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQT 532
Cdd:COG1196    424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  533 MQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLE 612
Cdd:COG1196    504 EGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  613 SLQ-QQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHAcieashqeqrqVQARVTELEAQLKAEQQKTTEREKVVQEK 691
Cdd:COG1196    584 ARAaLAAALARGAIGAAVDLVASDLREADARYYVLGDTLL-----------GRTLVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  692 AQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEA 771
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 2214681115  772 HQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEAR 814
Cdd:COG1196    733 EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
PRK06975 super family cl35524
bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed
 1566-1754 2.11e-03

bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed


The actual alignment was detected with superfamily member PRK06975:

Pssm-ID: 235899 [Multi-domain]  Cd Length: 656  Bit Score: 43.17  E-value: 2.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1566 QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQaaehyKLQMEKAKThydakkqqnQKLQEQLQDLeeLQKENKELR 1645
Cdd:PRK06975   357 QRQQANDAQTAELRVKTEQAQASVHQLDSQFAQLDG-----KLADAQSAQ---------QALEQQYQDL--SRNRDDWMI 420

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1646 SEAERLgreLQQAGLKTkeaeqtcrHLTAQVRSLEAQVAHADQQLRDLGKFQVAT---------DALKSrepqvKPQLDL 1716
Cdd:PRK06975   421 AEVEQM---LSSASQQL--------QLTGNVQLALIALQNADARLATSDSPQAVAvrkaiaqdiERLKA-----APSADL 484

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1717 S------------IDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASP 1754
Cdd:PRK06975   485 TglaiklddaiakIDALPLSGEALPPHATMAAAPAAAAAAAAAAAAAGEP 534
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-151 1.26e-49

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 173.14  E-value: 1.26e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115    6 TRAATLLSWVNSLHVADPVETVLQLQDCSIFIKIINTIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2214681115   86 KVIEG--SEMELAKMIMLFLYQSTMSSRNlrDWEQFEYGVQAELAVILKFMLDHEESLNLTEDLESFL 151
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNL--TLEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFL 147
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 554-1323 1.40e-27

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 122.47  E-value: 1.40e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  554 LKLKEQQlEEAAKEQEATRQDHAQQLAIVAEAREA--SL-RERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT 630
Cdd:TIGR02168  168 SKYKERR-KETERKLERTRENLDRLEDILNELERQlkSLeRQAEKAERYKELKAELRELELALLVLRLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  631 SVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLkaeQQKTTEREKVVQEKAQLQEQLRALEESLKITKG 710
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL---YALANEISRLEQQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  711 SLEEEKRRaadaLKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHqaetEALRHELAEATASQ 790
Cdd:TIGR02168  324 QLEELESK----LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL----ETLRSKVAQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  791 HRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAK 870
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  871 AIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASlELLKEPPRAANRASDQLGEQQGRPFSST 950
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS-ELISVDEGYEAAIEAALGGRLQAVVVEN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  951 -HAAVKAMEREAEQMGG-----ELERLRAALIKSQGQQQEERGQQEREVA-RLTQERGQAQADL---------------A 1008
Cdd:TIGR02168  555 lNAAKKAIAFLKQNELGrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAkDLVKFDPKLRKALsyllggvlvvddldnA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1009 QEKAAKAELEMRLQnTLNEQRVE---FAALQEALAHALTekEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKE 1085
Cdd:TIGR02168  635 LELAKKLRPGYRIV-TLDGDLVRpggVITGGSAKTNSSI--LERRREIEELEEKIEELEEKIAELEKALAELRKELEELE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1086 KEHPAGGASGEDASgpGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQG 1165
Cdd:TIGR02168  712 EELEQLRKELEELS--RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1166 QLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESK 1245
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1246 ELKRLVVAESEKSQKLEERLRLL--QVETASNSARAAE-RSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELG 1322
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEY 949


                   .
gi 2214681115 1323 Q 1323
Cdd:TIGR02168  950 S 950
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 515-1129 9.53e-27

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 119.66  E-value: 9.53e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  515 LASLKEQAKK-EQAQMLQTmQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEqeatrqdhaqqlaivAEAREASLRER 593
Cdd:COG1196    202 LEPLERQAEKaERYRELKE-ELKELEAELLLLKLRELEAELEELEAELEELEAE---------------LEELEAELAEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  594 DTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQ 673
Cdd:COG1196    266 EAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEE 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  674 LKAEQQkttEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQqcratemeAESRSLMEQREREQKELEQ 753
Cdd:COG1196    346 LEEAEE---ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA--------AELAAQLEELEEAEEALLE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  754 EKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEarygamfQEQLMALK 833
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL-------AELLEELA 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  834 GEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDD-LSALQEKMAATNKEVACLKTLVLK 912
Cdd:COG1196    488 EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAaLAAALQNIVVEDDEVAAAAIEYLK 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  913 AGEQQETASLELLKEPPRAANRASDQLGEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQERE 992
Cdd:COG1196    568 AAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  993 VARLTQERGQAQADLAQEKAAKaelemrlqntlNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQ 1072
Cdd:COG1196    648 EVTLEGEGGSAGGSLTGGSRRE-----------LLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2214681115 1073 TLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAGKTDAPGPELQALRAEISKLE 1129
Cdd:COG1196    717 LEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1866-1924 4.54e-26

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 102.68  E-value: 4.54e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115 1866 LLSLPGYRPTTRSSARRSQarmSSGAPQGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1924
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1117-1652 1.53e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.79  E-value: 1.53e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1117 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1196
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1197 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVA-ESEKSQKLEERLRLLQ--VETA 1273
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEaEEELEELAEELLEALRaaAELA 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1274 SNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALV 1353
Cdd:COG1196    400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1354 SELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAEL--------------MRAQRELGELGSLRQKIVEQERAA 1419
Cdd:COG1196    480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagavavligveaaYEAALEAALAAALQNIVVEDDEVA 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1420 QQ----LRAEKASYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDqAREKYVQELAAVRTDAETHLAEMRQE 1493
Cdd:COG1196    560 AAaieyLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREAD-ARYYVLGDTLLGRTLVAARLEAALRR 638

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1494 AQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEvfqrEQTKQVEELSKKLTEHDQASKVQQQKLKAFQA 1573
Cdd:COG1196    639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE----ELAERLAEEELELEEALLAEEEEERELAEAEE 714

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115 1574 QRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKthydakkqqnqklQEQLQDLEELQKENKELRSEAERLG 1652
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE-------------LPEPPDLEELERELERLEREIEALG 780
PTZ00121 PTZ00121
MAEBL; Provisional
 265-937 2.15e-20

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 99.45  E-value: 2.15e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  265 KQAASSQEPSELEELRGKNESLTV----RLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAfn 340
Cdd:PTZ00121  1203 EAARKAEEERKAEEARKAEDAKKAeavkKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA-- 1280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  341 dliEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKlSQLEDQATRLQEspAPEKGEVLGDALQLDTLKQEA 420
Cdd:PTZ00121  1281 ---DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAK-KKAEEAKKKADA--AKKKAEEAKKAAEAAKAEAEA 1354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  421 AKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTS 500
Cdd:PTZ00121  1355 AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAD 1434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  501 MTGLNATLQQRDQELASLKEQAKKeqAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLA 580
Cdd:PTZ00121  1435 EAKKKAEEAKKADEAKKKAEEAKK--AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKA 1512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  581 ivAEAREAS-LRERDTARQQLETVEKEKDAKLESLQQ--QLQAANDARDNAQtsVTQAQQEKAELSQKIGELHACIEASH 657
Cdd:PTZ00121  1513 --DEAKKAEeAKKADEAKKAEEAKKADEAKKAEEKKKadELKKAEELKKAEE--KKKAEEAKKAEEDKNMALRKAEEAKK 1588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  658 QEQRQVQA--RVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKgslEEEKRRAADALKEQQCRATEMEA 735
Cdd:PTZ00121  1589 AEEARIEEvmKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKE---AEEKKKAEELKKAEEENKIKAAE 1665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  736 ESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQ 815
Cdd:PTZ00121  1666 EAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK 1745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  816 QEEARYGAMFQEQLMALKG--EKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKA---IQQVQEKEVRAQKLVDDls 890
Cdd:PTZ00121  1746 AEEAKKDEEEKKKIAHLKKeeEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIfdnFANIIEGGKEGNLVIND-- 1823

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 2214681115  891 aLQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASD 937
Cdd:PTZ00121  1824 -SKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEAD 1869
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 213-814 2.22e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 98.86  E-value: 2.22e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  213 QMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALlnekqaassqepsELEELRGKNESLTVRLHE 292
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELAR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  293 TLKQCQNLKTEKSQMDRKISQLSEENgdlsfkvrefanhlqqlqgafndlieehskasQEWAEKQARLENELSTALQDKK 372
Cdd:COG1196    300 LEQDIARLEERRRELEERLEELEEEL--------------------------------AELEEELEELEEELEELEEELE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  373 CLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLEcergKQEAQLLAER 452
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL----ERLERLEEEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  453 SRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQT 532
Cdd:COG1196    424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  533 MQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLE 612
Cdd:COG1196    504 EGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  613 SLQ-QQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHAcieashqeqrqVQARVTELEAQLKAEQQKTTEREKVVQEK 691
Cdd:COG1196    584 ARAaLAAALARGAIGAAVDLVASDLREADARYYVLGDTLL-----------GRTLVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  692 AQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEA 771
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 2214681115  772 HQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEAR 814
Cdd:COG1196    733 EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1003-1695 1.14e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.66  E-value: 1.14e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1003 AQADLAQEKAAKAELEMRLqNTLNEQR---VEFAALQEALAHA-----LTEKEGTDQELAKLRGQEAAQRTELKELQQTL 1074
Cdd:TIGR02168  184 TRENLDRLEDILNELERQL-KSLERQAekaERYKELKAELRELelallVLRLEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1075 EQLKIQLVKKEKEHPAGGASGEDASGpgtqsetagktdapgpELQALRAEISKLEQQCQQQQQQVEGLTHSLKseracra 1154
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQK----------------ELYALANEISRLEQQKQILRERLANLERQLE------- 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1155 EQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILN 1234
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1235 rqvlekegeskelKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQ 1314
Cdd:TIGR02168  400 -------------NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1315 AERAEELGQELKAWQEKFFQKEQ---ALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKrFREELEQSKQAAGG- 1390
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQArldSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGYEAAIEAALGg 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1391 -LQAELMR------------AQRELG-------------ELGSLRQKIVEQERAAQQLRAEKASYAEQLSM--------- 1435
Cdd:TIGR02168  546 rLQAVVVEnlnaakkaiaflKQNELGrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggv 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1436 -----LKKAHGLLAEENRGL-------------------GERANLGRQFLEVELDQAREKY------VQELAAVRTDAET 1485
Cdd:TIGR02168  626 lvvddLDNALELAKKLRPGYrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIeeleekIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1486 HLAEMRQEAQSTSRELEVMTAKYEGAKvkvlEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQ 1565
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALR----KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1566 QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELR 1645
Cdd:TIGR02168  782 AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2214681115 1646 SEAERLGRELQ---QAGLKTKEAEQTCRH--------LTAQVRSLEAQVAHADQQLRDLGK 1695
Cdd:TIGR02168  862 EELEELIEELEselEALLNERASLEEALAllrseleeLSEELRELESKRSELRRELEELRE 922
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 211-844 4.18e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.19  E-value: 4.18e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  211 QFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASSQEPS--------ELEELRGK 282
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELEsrleeleeQLETLRSK 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  283 NESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANH------------LQQLQGAFNDLIEEHSKAS 350
Cdd:TIGR02168  388 VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKelqaeleeleeeLEELQEELERLEEALEELR 467

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  351 QEWAEKQARL---ENELSTALQDKKCLEEKNEILQG----------KLSQLEDQATRLQESPAPEKG------EVLGDAL 411
Cdd:TIGR02168  468 EELEEAEQALdaaERELAQLQARLDSLERLQENLEGfsegvkallkNQSGLSGILGVLSELISVDEGyeaaieAALGGRL 547

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  412 Q-------------LDTLKQEAAKLATD---NTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSN 475
Cdd:TIGR02168  548 QavvvenlnaakkaIAFLKQNELGRVTFlplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLV 627

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  476 LSQAKEELEQASQAQGAQLTAQLT--------SMTG----LNATLQQRDQELASLKEQakkeQAQMLQTMQEQEQAAQGL 543
Cdd:TIGR02168  628 VDDLDNALELAKKLRPGYRIVTLDgdlvrpggVITGgsakTNSSILERRREIEELEEK----IEELEEKIAELEKALAEL 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  544 RQQVEQLSSSLKLKEQQLEEAAKEQEATRQDhAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAAND 623
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA 782

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  624 ARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQ-----------QKTTEREKVVQEKA 692
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATErrledleeqieELSEDIESLAAEIE 862

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  693 QLQEQLRALE---ESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLE 769
Cdd:TIGR02168  863 ELEELIEELEselEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  770 EAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRF--------EARQQEEARYGAMFQEQLMALKGEKTGQEV 841
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaiEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022


                   ...
gi 2214681115  842 QEE 844
Cdd:TIGR02168 1023 IEE 1025
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
243-750 4.52e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 75.08  E-value: 4.52e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  243 TEKDAQIAMMQQRIDHlALLNEKQAASSQEPSELEEL----------RGKNESLTVRLHETLKQCQNLKTEKSQMDRKIS 312
Cdd:PRK02224   190 DQLKAQIEEKEEKDLH-ERLNGLESELAELDEEIERYeeqreqaretRDEADEVLEEHEERREELETLEAEIEDLRETIA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  313 QLSEENGDLSFKVREFANHLQQLQGAFNDL----------IEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQ 382
Cdd:PRK02224   269 ETEREREELAEEVRDLRERLEELEEERDDLlaeaglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  383 GKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQL 462
Cdd:PRK02224   349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  463 ASLIADLQSSVSNLSQAKEELEQA--------------------SQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQA 522
Cdd:PRK02224   429 AELEATLRTARERVEEAEALLEAGkcpecgqpvegsphvetieeDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  523 K-----KEQAQMLQ--------TMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQdhaqqlaiVAEAREAS 589
Cdd:PRK02224   509 DrierlEERREDLEeliaerreTIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEARE--------EVAELNSK 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  590 LRERDTARQQLETVEkEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACI-EASHQEQRQVQARVT 668
Cdd:PRK02224   581 LAELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFdEARIEEAREDKERAE 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  669 ELEAQLKAE-QQKTTEREKVVQEKAQLQEQLRALEEsLKITKGSLeEEKRRAADALKEQQCRATEMEAESRSLMEQRERE 747
Cdd:PRK02224   660 EYLEQVEEKlDELREERDDLQAEIGAVENELEELEE-LRERREAL-ENRVEALEALYDEAEELESMYGDLRAELRQRNVE 737


                   ...
gi 2214681115  748 QKE 750
Cdd:PRK02224   738 TLE 740
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 512-1339 6.16e-12

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 71.54  E-value: 6.16e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  512 DQELASLKEQAKKEQAQmLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQlAIVAEAREASLR 591
Cdd:pfam02463  159 EEEAAGSRLKRKKKEAL-KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEE-YLLYLDYLKLNE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  592 ERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELhacIEASHQEQRQVQARVTELE 671
Cdd:pfam02463  237 ERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKE---EEELKSELLKLERRKVDDE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  672 AQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKEL 751
Cdd:pfam02463  314 EKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  752 EQEKAGRKGLEARIQqlEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMA 831
Cdd:pfam02463  394 EEELELKSEEEKEAQ--LLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  832 LKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEK-----------------EVRAQKLVDDLSALQE 894
Cdd:pfam02463  472 DLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDgvggriisahgrlgdlgVAVENYKVAISTAVIV 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  895 KMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGRPF--SSTHAAVKAMEREAEQMGGELERLR 972
Cdd:pfam02463  552 EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNlaQLDKATLEADEDDKRAKVVEGILKD 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  973 AALIKSQGQQQEERGQQEREVARL-----TQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKE 1047
Cdd:pfam02463  632 TELTKLKESAKAKESGLRKGVSLEeglaeKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1048 GTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEhpagGASGEDASGPGTQSETAGKTDAPGPELQALRAEISK 1127
Cdd:pfam02463  712 LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEE----EEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLK 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1128 LEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKA 1207
Cdd:pfam02463  788 VEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEE 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1208 QVARG------QQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAE 1281
Cdd:pfam02463  868 LLQELllkeeeLEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADE 947

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2214681115 1282 RSSA------LREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQAL 1339
Cdd:pfam02463  948 KEKEennkeeEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAI 1011
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 450-648 9.06e-12

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 71.02  E-value: 9.06e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  450 AERSRFEDEKQQLASLIADLQSSVSNLSQAKeeLEQASQAQGAQL-------TAQLTSMT-GLNAtLQQRDQELASLKEQ 521
Cdd:NF012221  1569 ADRQRLEQEKQQQLAAISGSQSQLESTDQNA--LETNGQAQRDAIleesravTKELTTLAqGLDA-LDSQATYAGESGDQ 1645

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  522 AKKEQAQ-MLQTMQEQ-EQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQ-----QLAIVAEAREASLRERD 594
Cdd:NF012221  1646 WRNPFAGgLLDRVQEQlDDAKKISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQGEQnqanaEQDIDDAKADAEKRKDD 1725

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2214681115  595 TARQQLETVEKEKDAKLESLQQQLQAANDARdNAQTSVTQAQQEKAELSQKIGE 648
Cdd:NF012221  1726 ALAKQNEAQQAESDANAAANDAQSRGEQDAS-AAENKANQAQADAKGAKQDESD 1778
PTZ00121 PTZ00121
MAEBL; Provisional
 1144-1667 6.33e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.24  E-value: 6.33e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1144 HSLKSERACRAEQDKALETLQGQLEEKARElgHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLI 1223
Cdd:PTZ00121  1056 HEGKAEAKAHVGQDEGLKPSYKDFDFDAKE--DNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEA 1133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1224 SSLEEEVSIlnrqvlEKEGESKELKRLVVA-ESEKSQKLEERLRLLQVETASNSARAAERSSAlrEEVQSLRE--EVEKQ 1300
Cdd:PTZ00121  1134 RKAEDARKA------EEARKAEDAKRVEIArKAEDARKAEEARKAEDAKKAEAARKAEEVRKA--EELRKAEDarKAEAA 1205

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1301 RVVSENSRQELASQAERAEELgQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHlcQQLQAEQAAAEKRFREE 1380
Cdd:PTZ00121  1206 RKAEEERKAEEARKAEDAKKA-EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHF--ARRQAAIKAEEARKADE 1282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1381 LEQSKQAAgglQAELMRAQRELGELGSLRQKiVEQERAAQQLRAEKASYAEQLSMLKKAhgllAEENRGLGERAnlgrqf 1460
Cdd:PTZ00121  1283 LKKAEEKK---KADEAKKAEEKKKADEAKKK-AEEAKKADEAKKKAEEAKKKADAAKKK----AEEAKKAAEAA------ 1348

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1461 leveldqarekyvqelaavrtdaethlaemRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKltaqveqlevfq 1540
Cdd:PTZ00121  1349 ------------------------------KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK------------ 1386

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1541 REQTKQVEELSKKLTEHDQasKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAK 1620
Cdd:PTZ00121  1387 AEEKKKADEAKKKAEEDKK--KADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1621 KQQNQKLQEQLQDLEELQKENKELRSEAERLGR---ELQQAGLKTKEAEQ 1667
Cdd:PTZ00121  1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKkadEAKKAAEAKKKADE 1514
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1202-1695 4.24e-09

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 62.05  E-value: 4.24e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1202 EEEWKAQVARGQQEAERKSSlissleEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRllqvETASNSARAAE 1281
Cdd:pfam05483  103 QKENKLQENRKIIEAQRKAI------QELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLK----ETCARSAEKTK 172

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1282 RSSALREEVQSLREEV-----------EKQRVVSENSRQELASQAERAEELGQEL-KAWQEKFFQKEQALSALQLEHTST 1349
Cdd:pfam05483  173 KYEYEREETRQVYMDLnnniekmilafEELRVQAENARLEMHFKLKEDHEKIQHLeEEYKKEINDKEKQVSLLLIQITEK 252

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1350 QALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAEL----MRAQRELGELGSLRQKIVEQERAAQQLRAE 1425
Cdd:pfam05483  253 ENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELedikMSLQRSMSTQKALEEDLQIATKTICQLTEE 332

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1426 KASYAEQLSMLKKAHGLLAEENRG----LGERANLGRQFLEVELDQarekyVQELAAVRTDAETHLAEMRQEAQSTSREL 1501
Cdd:pfam05483  333 KEAQMEELNKAKAAHSFVVTEFEAttcsLEELLRTEQQRLEKNEDQ-----LKIITMELQKKSSELEEMTKFKNNKEVEL 407

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1502 EVMTaKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQE 1581
Cdd:pfam05483  408 EELK-KILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLK 486

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1582 VQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQkenKELRSEAERLGRELQQAGLK 1661
Cdd:pfam05483  487 NIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKE---MNLRDELESVREEFIQKGDE 563

                          490       500       510
                   ....*....|....*....|....*....|....*...
gi 2214681115 1662 TK----EAEQTCRHLTAQVRSLEAQVAHADQQLRDLGK 1695
Cdd:pfam05483  564 VKckldKSEENARSIEYEVLKKEKQMKILENKCNNLKK 601
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 252-817 2.89e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 59.42  E-value: 2.89e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  252 MQQRIDHLALLNEKQAASSQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKIS----QLSEENGDLSFKVRE 327
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAarkqELEEILHELESRLEE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  328 FANHLQQLQGafndlieEHSKASQEWAEKQARLENELST--ALQ-DKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKG 404
Cdd:pfam01576   87 EEERSQQLQN-------EKKKMQQHIQDLEEQLDEEEAArqKLQlEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  405 EVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQllaeRSRFEDEKQQLASLIADLQSSVSNLSQAKEELE 484
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKG----RQELEKAKRKLEGESTDLQEQIAELQAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  485 QASQAQGAQLTAQLTSM---TGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLklkEQQL 561
Cdd:pfam01576  236 AQLAKKEEELQAALARLeeeTAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL---EDTL 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  562 EEAAKEQEATRQDHAQqlaiVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAE 641
Cdd:pfam01576  313 DTTAAQQELRSKREQE----VTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAE 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  642 LSQKIGELHACIEASHQEQRQVQARVTELEAQL-KAEQQKTTEREKVVQEKAQLQEQLRALEE----SLKITK--GSLEE 714
Cdd:pfam01576  389 LQAELRTLQQAKQDSEHKRKKLEGQLQELQARLsESERQRAELAEKLSKLQSELESVSSLLNEaegkNIKLSKdvSSLES 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  715 EKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLeeahQAETEALRHELAEATASQHRAE 794
Cdd:pfam01576  469 QLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTL----QAQLSDMKKKLEEDAGTLEALE 544

                          570       580
                   ....*....|....*....|...
gi 2214681115  795 SECERLIREVESRQKRFEARQQE 817
Cdd:pfam01576  545 EGKKRLQRELEALTQQLEEKAAA 567
HpsJ_fam NF038305
HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the ...
 503-619 1.30e-05

HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the biosynthesis or secretion of an extracellular polysaccharide shared by many Cyanobacteria.


Pssm-ID: 468465 [Multi-domain]  Cd Length: 230  Bit Score: 48.73  E-value: 1.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  503 GLNATLQQRDQELASLKEQAKKEQAQmLQTMQEQEQAAQGlRQQVEQLSSSLKLKEQQLEEAAKEQEaTRQDHAQQLAIV 582
Cdd:NF038305    98 HLNNTRRLSTQALQQINQQAGQQETQ-LQQQLNQLQAQTS-PQQLNQLLKSEQKQGQALASGQLPEE-QKEQLQQFKSNP 174

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 2214681115  583 AEAREASLRERDTARQQLETVEKEkdAKLESLQQQLQ 619
Cdd:NF038305   175 QALDKFLAQQLTQIRTQAEEAEKQ--ARLEALKSSLR 209
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 577-954 4.50e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.06  E-value: 4.50e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  577 QQLAIVAEAREASLRERDTARQQ-LETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGElhaciea 655
Cdd:NF012221  1503 KTLKLTAKAGSNRLEFKGTGHNDgLGYILDNVVATSESSQQADAVSKHAKQDDAAQNALADKERAEADRQRLE------- 1575

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  656 shQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGsleeekrraADALKEQQCRATEMEA 735
Cdd:NF012221  1576 --QEKQQQLAAISGSQSQLESTDQNALETNGQAQRDAILEESRAVTKELTTLAQG---------LDALDSQATYAGESGD 1644

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  736 ESRSLMEQR--EREQKELEQEKagrKGLEARIQQLEEAHQAETEALRHELAEATASQHRAesecERLIREVESRQKrfEA 813
Cdd:NF012221  1645 QWRNPFAGGllDRVQEQLDDAK---KISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQG----EQNQANAEQDID--DA 1715

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  814 RQQEEARYGAMFQEQLMALKGEKTGQEVQEEAveihseGQPGQQQSQLAQLHASLAKAiqqvqekevraqklvDDLSALQ 893
Cdd:NF012221  1716 KADAEKRKDDALAKQNEAQQAESDANAAANDA------QSRGEQDASAAENKANQAQA---------------DAKGAKQ 1774

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2214681115  894 EKMAATNKEVACLKTLVLKAGEQQETA--SLELLKEPPRAAN-RASDQLGEQQGRPFSSTHAAV 954
Cdd:NF012221  1775 DESDKPNRQGAAGSGLSGKAYSVEGVAepGSHINPDSPAAADgRFSEGLTEQEQEALEGATNAV 1838
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 850-1120 1.03e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  850 SEGQpgQQQSQLAQlHASLAKAIQQVQEKEVRA-----------QKLVDDLSALQEKMAATNKEVACLKTLVLKAG--EQ 916
Cdd:NF012221  1538 SESS--QQADAVSK-HAKQDDAAQNALADKERAeadrqrleqekQQQLAAISGSQSQLESTDQNALETNGQAQRDAilEE 1614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  917 QETASLELLKEPPR-AANRASDQLGEQQGRPFSsTHAAVKAMEREAEQM-------GGELERLRAALIKSQGQQQEERGQ 988
Cdd:NF012221  1615 SRAVTKELTTLAQGlDALDSQATYAGESGDQWR-NPFAGGLLDRVQEQLddakkisGKQLADAKQRHVDNQQKVKDAVAK 1693

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  989 QEREVARLTQERGQAQADLAQekaAKAELEMRLQNTLNEQRVefAALQEALAHALTEKegtdqelAKLRGQEAAQRTELK 1068
Cdd:NF012221  1694 SEAGVAQGEQNQANAEQDIDD---AKADAEKRKDDALAKQNE--AQQAESDANAAAND-------AQSRGEQDASAAENK 1761

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2214681115 1069 ELQQTLEQLKIQLVKKEKEHPAgGASGEDASGPGTQSETAGKTD-APGPELQA 1120
Cdd:NF012221  1762 ANQAQADAKGAKQDESDKPNRQ-GAAGSGLSGKAYSVEGVAEPGsHINPDSPA 1813
TOPEUc smart00435
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina ...
 1609-1692 1.56e-03

DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina virus topoisomerase, Variola virus topoisomerase, Shope fibroma virus topoisomeras


Pssm-ID: 214661 [Multi-domain]  Cd Length: 391  Bit Score: 43.11  E-value: 1.56e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  1609 QMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQ 1688
Cdd:smart00435  278 SMEKLQEKIKALKYQLKRLKKMILLFEMISDLKRKLKSKFERDNEKLDAEVKEKKKEKKKEEKKKKQIERLEERIEKLEV 357


                    ....
gi 2214681115  1689 QLRD 1692
Cdd:smart00435  358 QATD 361
PRK06975 PRK06975
bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed
 1566-1754 2.11e-03

bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed


Pssm-ID: 235899 [Multi-domain]  Cd Length: 656  Bit Score: 43.17  E-value: 2.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1566 QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQaaehyKLQMEKAKThydakkqqnQKLQEQLQDLeeLQKENKELR 1645
Cdd:PRK06975   357 QRQQANDAQTAELRVKTEQAQASVHQLDSQFAQLDG-----KLADAQSAQ---------QALEQQYQDL--SRNRDDWMI 420

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1646 SEAERLgreLQQAGLKTkeaeqtcrHLTAQVRSLEAQVAHADQQLRDLGKFQVAT---------DALKSrepqvKPQLDL 1716
Cdd:PRK06975   421 AEVEQM---LSSASQQL--------QLTGNVQLALIALQNADARLATSDSPQAVAvrkaiaqdiERLKA-----APSADL 484

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1717 S------------IDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASP 1754
Cdd:PRK06975   485 TglaiklddaiakIDALPLSGEALPPHATMAAAPAAAAAAAAAAAAAGEP 534
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-151 1.26e-49

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 173.14  E-value: 1.26e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115    6 TRAATLLSWVNSLHVADPVETVLQLQDCSIFIKIINTIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2214681115   86 KVIEG--SEMELAKMIMLFLYQSTMSSRNlrDWEQFEYGVQAELAVILKFMLDHEESLNLTEDLESFL 151
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNL--TLEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFL 147
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 554-1323 1.40e-27

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 122.47  E-value: 1.40e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  554 LKLKEQQlEEAAKEQEATRQDHAQQLAIVAEAREA--SL-RERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT 630
Cdd:TIGR02168  168 SKYKERR-KETERKLERTRENLDRLEDILNELERQlkSLeRQAEKAERYKELKAELRELELALLVLRLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  631 SVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLkaeQQKTTEREKVVQEKAQLQEQLRALEESLKITKG 710
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL---YALANEISRLEQQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  711 SLEEEKRRaadaLKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHqaetEALRHELAEATASQ 790
Cdd:TIGR02168  324 QLEELESK----LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL----ETLRSKVAQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  791 HRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAK 870
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  871 AIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASlELLKEPPRAANRASDQLGEQQGRPFSST 950
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS-ELISVDEGYEAAIEAALGGRLQAVVVEN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  951 -HAAVKAMEREAEQMGG-----ELERLRAALIKSQGQQQEERGQQEREVA-RLTQERGQAQADL---------------A 1008
Cdd:TIGR02168  555 lNAAKKAIAFLKQNELGrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAkDLVKFDPKLRKALsyllggvlvvddldnA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1009 QEKAAKAELEMRLQnTLNEQRVE---FAALQEALAHALTekEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKE 1085
Cdd:TIGR02168  635 LELAKKLRPGYRIV-TLDGDLVRpggVITGGSAKTNSSI--LERRREIEELEEKIEELEEKIAELEKALAELRKELEELE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1086 KEHPAGGASGEDASgpGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQG 1165
Cdd:TIGR02168  712 EELEQLRKELEELS--RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1166 QLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESK 1245
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1246 ELKRLVVAESEKSQKLEERLRLL--QVETASNSARAAE-RSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELG 1322
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEY 949


                   .
gi 2214681115 1323 Q 1323
Cdd:TIGR02168  950 S 950
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 515-1129 9.53e-27

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 119.66  E-value: 9.53e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  515 LASLKEQAKK-EQAQMLQTmQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEqeatrqdhaqqlaivAEAREASLRER 593
Cdd:COG1196    202 LEPLERQAEKaERYRELKE-ELKELEAELLLLKLRELEAELEELEAELEELEAE---------------LEELEAELAEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  594 DTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQ 673
Cdd:COG1196    266 EAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEE 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  674 LKAEQQkttEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQqcratemeAESRSLMEQREREQKELEQ 753
Cdd:COG1196    346 LEEAEE---ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA--------AELAAQLEELEEAEEALLE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  754 EKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEarygamfQEQLMALK 833
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL-------AELLEELA 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  834 GEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDD-LSALQEKMAATNKEVACLKTLVLK 912
Cdd:COG1196    488 EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAaLAAALQNIVVEDDEVAAAAIEYLK 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  913 AGEQQETASLELLKEPPRAANRASDQLGEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQERE 992
Cdd:COG1196    568 AAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  993 VARLTQERGQAQADLAQEKAAKaelemrlqntlNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQ 1072
Cdd:COG1196    648 EVTLEGEGGSAGGSLTGGSRRE-----------LLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2214681115 1073 TLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAGKTDAPGPELQALRAEISKLE 1129
Cdd:COG1196    717 LEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1866-1924 4.54e-26

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 102.68  E-value: 4.54e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115 1866 LLSLPGYRPTTRSSARRSQarmSSGAPQGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1924
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 553-1324 1.48e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 115.92  E-value: 1.48e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  553 SLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSV 632
Cdd:TIGR02168  204 SLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEI 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  633 TQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREK----VVQEKAQLQEQLRALEESLKIT 708
Cdd:TIGR02168  284 EELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEelaeLEEKLEELKEELESLEAELEEL 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  709 KGSLEEEKRRAAD---ALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLE-EAHQAETEALRHELA 784
Cdd:TIGR02168  364 EAELEELESRLEEleeQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLkKLEEAELKELQAELE 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  785 EATASQHRAESECERLIREVESRQKRFEARQQEEARygamFQEQLMALKGEKTGQEVQEEAVEIHSEG--QPGQQQSQLA 862
Cdd:TIGR02168  444 ELEEELEELQEELERLEEALEELREELEEAEQALDA----AERELAQLQARLDSLERLQENLEGFSEGvkALLKNQSGLS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  863 QLHASLAKAIqQVQEKEVRAqkLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQ 942
Cdd:TIGR02168  520 GILGVLSELI-SVDEGYEAA--IEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKN 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  943 QGRPFSSTHAAVKAMEREAEQMGGELERLR--------AALIKSQGQQQEERGQQEREVAR-------------LTQERG 1001
Cdd:TIGR02168  597 IEGFLGVAKDLVKFDPKLRKALSYLLGGVLvvddldnaLELAKKLRPGYRIVTLDGDLVRPggvitggsaktnsSILERR 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1002 QAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQL 1081
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1082 VKKEKEHPA-----GGASGEDASGPGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQ 1156
Cdd:TIGR02168  757 TELEAEIEEleerlEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1157 DKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQ 1236
Cdd:TIGR02168  837 ERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRE 916

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1237 VLEKEGESKELK----RLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELA 1312
Cdd:TIGR02168  917 LEELREKLAQLElrleGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYE 996

                          810
                   ....*....|..
gi 2214681115 1313 SQAERAEELGQE 1324
Cdd:TIGR02168  997 ELKERYDFLTAQ 1008
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 412-965 2.64e-24

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 111.57  E-value: 2.64e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  412 QLDTLKQEAAKlATDNTQLQTRVETLECE-RGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQ 490
Cdd:COG1196    201 QLEPLERQAEK-AERYRELKEELKELEAElLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  491 GAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSsLKLKEQQLEEAAKEQEA 570
Cdd:COG1196    280 ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEE-LEEELEEAEEELEEAEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  571 TRQDHAQQLAIVAEAREASLRERDTARQQLETVEK---EKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIG 647
Cdd:COG1196    359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRaaaELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  648 ELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALK--- 724
Cdd:COG1196    439 EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLlag 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  725 ------------------EQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEA 786
Cdd:COG1196    519 lrglagavavligveaayEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIG 598

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  787 TA-SQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLH 865
Cdd:COG1196    599 AAvDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  866 ASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGR 945
Cdd:COG1196    679 AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPE 758

                          570       580
                   ....*....|....*....|..
gi 2214681115  946 PFSSTHAA--VKAMEREAEQMG 965
Cdd:COG1196    759 PPDLEELEreLERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 330-870 1.98e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 108.87  E-value: 1.98e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  330 NHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGD 409
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  410 ALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQA 489
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  490 QgAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQE 569
Cdd:COG1196    395 A-AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  570 ATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQ---AANDARDNAQTSVTQAQQEKAELSQKI 646
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAgavAVLIGVEAAYEAALEAALAAALQNIVV 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  647 GELHACIEASHQEQRQVQARVTEL--EAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALK 724
Cdd:COG1196    554 EDDEVAAAAIEYLKAAKAGRATFLplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  725 EQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQhRAESECERLIREV 804
Cdd:COG1196    634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL-LAEEEEERELAEA 712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2214681115  805 ESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAK 870
Cdd:COG1196    713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 478-1077 2.13e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 108.87  E-value: 2.13e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  478 QAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMlqtmQEQEQAAQGLRQQVEQLSSSLKLK 557
Cdd:COG1196    211 KAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAEL----AELEAELEELRLELEELELELEEA 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  558 EQQLEEAAKEQEATRQD--HAQQLAIVAEAREASL-RERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQ 634
Cdd:COG1196    287 QAEEYELLAELARLEQDiaRLEERRRELEERLEELeEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  635 AQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEE 714
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  715 EKRRAADALKEqqcratemEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAhQAETEALRHELAEATASQHRAE 794
Cdd:COG1196    447 AAEEEAELEEE--------EEALLELLAELLEEAALLEAALAELLEELAEAAARLLL-LLEAEADYEGFLEGVKAALLLA 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  795 SECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALkgektgQEVQEEAVEIHSEGQPGQQQ-SQLAQLHASLAKAIQ 873
Cdd:COG1196    518 GLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVED------DEVAAAAIEYLKAAKAGRATfLPLDKIRARAALAAA 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  874 QVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEppRAANRASDQLGEQQGrpfSSTHAA 953
Cdd:COG1196    592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGR--LREVTLEGEGGSAGG---SLTGGS 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  954 VKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFA 1033
Cdd:COG1196    667 RRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE 746

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 2214681115 1034 ALQEALAHALTEKEgtdqelaklrgQEAAQRTELKELQQTLEQL 1077
Cdd:COG1196    747 LLEEEALEELPEPP-----------DLEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 275-1070 9.70e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 106.68  E-value: 9.70e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  275 ELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKvrefanhLQQLQGAFNDLIEEHSKASQEWA 354
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE-------IEELQKELYALANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  355 EKQARLENelstALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRV 434
Cdd:TIGR02168  306 ILRERLAN----LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  435 ETLECERGKQEAQLLAERSRFedekQQLASLIADLQSSVSNLSQAKEELEQasQAQGAQLTAQLTSMTGLNATLQQRDQE 514
Cdd:TIGR02168  382 ETLRSKVAQLELQIASLNNEI----ERLEARLERLEDRRERLQQEIEELLK--KLEEAELKELQAELEELEEELEELQEE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  515 LASLKEQAKKEQAQMlqtmQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQdhaqqlaiVAEAREASLRERD 594
Cdd:TIGR02168  456 LERLEEALEELREEL----EEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKA--------LLKNQSGLSGILG 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  595 TARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKA-------ELS----QKIGELHACIEASHQEQRQV 663
Cdd:TIGR02168  524 VLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNElgrvtflPLDsikgTEIQGNDREILKNIEGFLGV 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  664 QARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKI--------TKGSLEEEKRRAADALkeQQCRATEMEa 735
Cdd:TIGR02168  604 AKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIvtldgdlvRPGGVITGGSAKTNSS--ILERRREIE- 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  736 ESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQ 815
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  816 QEEARYGAMFQEQLMALKGEKTGQEVQEEAVEihsegqpgQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEK 895
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIE--------QLKEELKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  896 MAATNKEVACLKTLVLKAGEQQETASLEL--LKEPPRAANRASDQLGEQqgrpFSSTHAAVKAMEREAEQMGGELERLRa 973
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIeeLEELIEELESELEALLNE----RASLEEALALLRSELEELSEELRELE- 907

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  974 aliksqgqqqeergqqeREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEalaHALTEKEGTDQEL 1053
Cdd:TIGR02168  908 -----------------SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE---EAEALENKIEDDE 967

                          810
                   ....*....|....*..
gi 2214681115 1054 AKLRGQEAAQRTELKEL 1070
Cdd:TIGR02168  968 EEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 207-907 9.70e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 106.68  E-value: 9.70e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  207 LQTPQFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRI-DHLALLNEKQAASSQEPSELEELRGKNES 285
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELyALANEISRLEQQKQILRERLANLERQLEE 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  286 LTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAE---KQARLEN 362
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQlelQIASLNN 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  363 ELSTALQDKKCLEEKNEILQGKLSQLEDQatrlqespaPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERG 442
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKK---------LEEAELKELQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  443 KQEAQLLAERSRFEDEKQQLASL-----------------------IADLQSSVSNLSQAKEELEQA-SQAQGAQLTAQL 498
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLerlqenlegfsegvkallknqsgLSGILGVLSELISVDEGYEAAiEAALGGRLQAVV 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  499 TSmtglnaTLQQRDQELASLKeQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQ 578
Cdd:TIGR02168  552 VE------NLNAAKKAIAFLK-QNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGG 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  579 LAIVAEAREA-SLRERDTARQQLETVEKEKDAKLESLqqqlqaaNDARDNAQTSVTQAQQEKAELSQKIGELhacieash 657
Cdd:TIGR02168  625 VLVVDDLDNAlELAKKLRPGYRIVTLDGDLVRPGGVI-------TGGSAKTNSSILERRREIEELEEKIEEL-------- 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  658 qeqrqvQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAES 737
Cdd:TIGR02168  690 ------EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  738 RSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETE---ALRHELAEATASQHRAESECERLIREVESRQKRFEAR 814
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREaldELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  815 QQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEgQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQE 894
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEELEELIEELESELEALLN-ERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE 922

                          730
                   ....*....|...
gi 2214681115  895 KMAATNKEVACLK 907
Cdd:TIGR02168  923 KLAQLELRLEGLE 935
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1117-1652 1.53e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.79  E-value: 1.53e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1117 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1196
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1197 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVA-ESEKSQKLEERLRLLQ--VETA 1273
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEaEEELEELAEELLEALRaaAELA 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1274 SNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALV 1353
Cdd:COG1196    400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1354 SELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAEL--------------MRAQRELGELGSLRQKIVEQERAA 1419
Cdd:COG1196    480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagavavligveaaYEAALEAALAAALQNIVVEDDEVA 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1420 QQ----LRAEKASYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDqAREKYVQELAAVRTDAETHLAEMRQE 1493
Cdd:COG1196    560 AAaieyLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREAD-ARYYVLGDTLLGRTLVAARLEAALRR 638

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1494 AQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEvfqrEQTKQVEELSKKLTEHDQASKVQQQKLKAFQA 1573
Cdd:COG1196    639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE----ELAERLAEEELELEEALLAEEEEERELAEAEE 714

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115 1574 QRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKthydakkqqnqklQEQLQDLEELQKENKELRSEAERLG 1652
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE-------------LPEPPDLEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1117-1636 1.42e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 102.71  E-value: 1.42e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1117 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1196
Cdd:COG1196    254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELE 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1197 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNS 1276
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1277 ARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1356
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1357 LPAKHLcqQLQAEQAAAEKRFREELEQSKQAAGGLQAEL-----MRAQRELGELGSLRQKIVEQERAAQQ----LRAEKA 1427
Cdd:COG1196    494 LLLLEA--EADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaaYEAALEAALAAALQNIVVEDDEVAAAaieyLKAAKA 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1428 SYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELD---QAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELE 1502
Cdd:COG1196    572 GRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREADaryYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTL 651

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1503 VMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEV 1582
Cdd:COG1196    652 EGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2214681115 1583 QRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTH------------------------YDAKKQQNQKLQEQLQDLEE 1636
Cdd:COG1196    732 AEREELLEELLEEEELLEEEALEELPEPPDLEELerelerlereiealgpvnllaieeYEELEERYDFLSEQREDLEE 809
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 213-903 2.65e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 102.06  E-value: 2.65e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  213 QMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHL-----ALLNEKQAASSQE---PSELEELRGKNE 284
Cdd:TIGR02168  240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELqkelyALANEISRLEQQKqilRERLANLERQLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  285 SLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAE---KQARLE 361
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQlelQIASLN 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  362 NELSTALQDKKCLEEKNEILQGKLSQLEDQatrlqespaPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECER 441
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKK---------LEEAELKELQAELEELEEELEELQEELERLEEALEELREEL 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  442 GKQEAQLLAERSRFEDEKQQLASL-----------------------IADLQSSVSNLSQAKEELEQA-SQAQGAQLTAQ 497
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLerlqenlegfsegvkallknqsgLSGILGVLSELISVDEGYEAAiEAALGGRLQAV 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  498 LtsMTGLNATLQ--------------------QRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKL- 556
Cdd:TIGR02168  551 V--VENLNAAKKaiaflkqnelgrvtflpldsIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVv 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  557 ------KEQQLEEAAKEQEATRQDH--AQQLAIVAEAREASL------RERDTARQQLETVE---KEKDAKLESLQQQLQ 619
Cdd:TIGR02168  629 ddldnaLELAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSsilerrREIEELEEKIEELEekiAELEKALAELRKELE 708

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  620 AANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTE-----------REKVV 688
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEaeeelaeaeaeIEELE 788

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  689 QEKAQLQEQLRALEESLKITKGSLEEEKRRAADA----------LKEQQCRATEMEAESRSLMEQREREQKELEQEKAGR 758
Cdd:TIGR02168  789 AQIEQLKEELKALREALDELRAELTLLNEEAANLrerleslerrIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI 868

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  759 KGLEARIQQLEE---AHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMAL--K 833
Cdd:TIGR02168  869 EELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLseE 948

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  834 GEKTGQEVQEEAVEIhsEGQPGQQQSQLAQLHASLAK-------AIQQVQEKEVR-----AQK--LVDDLSALQEKMAAT 899
Cdd:TIGR02168  949 YSLTLEEAEALENKI--EDDEEEARRRLKRLENKIKElgpvnlaAIEEYEELKERydfltAQKedLTEAKETLEEAIEEI 1026


                   ....
gi 2214681115  900 NKEV 903
Cdd:TIGR02168 1027 DREA 1030
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1119-1695 2.09e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 98.86  E-value: 2.09e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1119 QALRAEISKLEqqcqqqqqqVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDH 1198
Cdd:COG1196    216 RELKEELKELE---------AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1199 SKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSAR 1278
Cdd:COG1196    287 QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1279 AAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLP 1358
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1359 AKHLCQQLQAEQAAAEKRFREELEQSKQAagglQAELMRAQRELGELGSlRQKIVEQERAAQQLRAEKASYAEQLSMLKK 1438
Cdd:COG1196    447 AAEEEAELEEEEEALLELLAELLEEAALL----EAALAELLEELAEAAA-RLLLLLEAEADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1439 AHGLLAEENRG-------LGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGA 1511
Cdd:COG1196    522 LAGAVAVLIGVeaayeaaLEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1512 KVKVLEERqrfqEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNE 1591
Cdd:COG1196    602 DLVASDLR----EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1592 LQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRH 1671
Cdd:COG1196    678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                          570       580
                   ....*....|....*....|....
gi 2214681115 1672 LTAQVRSLEAQVAHADQQLRDLGK 1695
Cdd:COG1196    758 EPPDLEELERELERLEREIEALGP 781
PTZ00121 PTZ00121
MAEBL; Provisional
 265-937 2.15e-20

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 99.45  E-value: 2.15e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  265 KQAASSQEPSELEELRGKNESLTV----RLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAfn 340
Cdd:PTZ00121  1203 EAARKAEEERKAEEARKAEDAKKAeavkKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA-- 1280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  341 dliEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKlSQLEDQATRLQEspAPEKGEVLGDALQLDTLKQEA 420
Cdd:PTZ00121  1281 ---DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAK-KKAEEAKKKADA--AKKKAEEAKKAAEAAKAEAEA 1354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  421 AKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTS 500
Cdd:PTZ00121  1355 AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAD 1434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  501 MTGLNATLQQRDQELASLKEQAKKeqAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLA 580
Cdd:PTZ00121  1435 EAKKKAEEAKKADEAKKKAEEAKK--AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKA 1512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  581 ivAEAREAS-LRERDTARQQLETVEKEKDAKLESLQQ--QLQAANDARDNAQtsVTQAQQEKAELSQKIGELHACIEASH 657
Cdd:PTZ00121  1513 --DEAKKAEeAKKADEAKKAEEAKKADEAKKAEEKKKadELKKAEELKKAEE--KKKAEEAKKAEEDKNMALRKAEEAKK 1588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  658 QEQRQVQA--RVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKgslEEEKRRAADALKEQQCRATEMEA 735
Cdd:PTZ00121  1589 AEEARIEEvmKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKE---AEEKKKAEELKKAEEENKIKAAE 1665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  736 ESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQ 815
Cdd:PTZ00121  1666 EAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK 1745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  816 QEEARYGAMFQEQLMALKG--EKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKA---IQQVQEKEVRAQKLVDDls 890
Cdd:PTZ00121  1746 AEEAKKDEEEKKKIAHLKKeeEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIfdnFANIIEGGKEGNLVIND-- 1823

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 2214681115  891 aLQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASD 937
Cdd:PTZ00121  1824 -SKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEAD 1869
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 213-814 2.22e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 98.86  E-value: 2.22e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  213 QMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALlnekqaassqepsELEELRGKNESLTVRLHE 292
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELAR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  293 TLKQCQNLKTEKSQMDRKISQLSEENgdlsfkvrefanhlqqlqgafndlieehskasQEWAEKQARLENELSTALQDKK 372
Cdd:COG1196    300 LEQDIARLEERRRELEERLEELEEEL--------------------------------AELEEELEELEEELEELEEELE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  373 CLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLEcergKQEAQLLAER 452
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL----ERLERLEEEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  453 SRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQT 532
Cdd:COG1196    424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  533 MQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLE 612
Cdd:COG1196    504 EGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  613 SLQ-QQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHAcieashqeqrqVQARVTELEAQLKAEQQKTTEREKVVQEK 691
Cdd:COG1196    584 ARAaLAAALARGAIGAAVDLVASDLREADARYYVLGDTLL-----------GRTLVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  692 AQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEA 771
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 2214681115  772 HQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEAR 814
Cdd:COG1196    733 EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 856-1636 7.82e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.43  E-value: 7.82e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  856 QQQSQLAQLHASLakaiqQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLvLKAGEQQETASLELLKEPPRAANRA 935
Cdd:TIGR02168  206 ERQAEKAERYKEL-----KAELRELELALLVLRLEELREELEELQEELKEAEEE-LEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  936 SDQLGEQQGRPFSSThAAVKAMEREAEQMGGELERLRAaliksqgqqqeERGQQEREVARLTQERGQAQADLAQEKAAKA 1015
Cdd:TIGR02168  280 EEEIEELQKELYALA-NEISRLEQQKQILRERLANLER-----------QLEELEAQLEELESKLDELAEELAELEEKLE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1016 ELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQ---ELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGG 1092
Cdd:TIGR02168  348 ELKEELESLEAELEELEAELEELESRLEELEEQLETlrsKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELL 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1093 ASGEDASGPGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDkALETLQGQLEEKAR 1172
Cdd:TIGR02168  428 KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD-SLERLQENLEGFSE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1173 ELghnqAASASAQRELQALRAKAQDHSKAEEEWKA------------------QVARGQQEAERKSSLI-SSLEEEVSIL 1233
Cdd:TIGR02168  507 GV----KALLKNQSGLSGILGVLSELISVDEGYEAaieaalggrlqavvvenlNAAKKAIAFLKQNELGrVTFLPLDSIK 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1234 NRQVLEKEGESKELKRLVVAESEKSQKLEERLRLL------QVETASNSARAAERSSALREE---VQSLREEVEKQRVVS 1304
Cdd:TIGR02168  583 GTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllgGVLVVDDLDNALELAKKLRPGyriVTLDGDLVRPGGVIT 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1305 ENSRQELASQAERA---EELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEL 1381
Cdd:TIGR02168  663 GGSAKTNSSILERRreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEV 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1382 EQSKQAAGGLQAELMRAQRE----LGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLG 1457
Cdd:TIGR02168  743 EQLEERIAQLSKELTELEAEieelEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1458 RQFLEVELDQAREKyvqelaavrtdaETHLAEMRQEAQSTSRELEVMTAKYEGAKvkvlEERQRFQEERQKLTAQVEQLE 1537
Cdd:TIGR02168  823 RERLESLERRIAAT------------ERRLEDLEEQIEELSEDIESLAAEIEELE----ELIEELESELEALLNERASLE 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1538 VFQREQTKQVEELSKKLTEHDqaskvqqQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQ-KEQAAEHYKLQMEKAKTH 1616
Cdd:TIGR02168  887 EALALLRSELEELSEELRELE-------SKRSELRRELEELREKLAQLELRLEGLEVRIDNlQERLSEEYSLTLEEAEAL 959

                          810       820
                   ....*....|....*....|
gi 2214681115 1617 YDAKKQQNQKLQEQLQDLEE 1636
Cdd:TIGR02168  960 ENKIEDDEEEARRRLKRLEN 979
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1003-1695 1.14e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.66  E-value: 1.14e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1003 AQADLAQEKAAKAELEMRLqNTLNEQR---VEFAALQEALAHA-----LTEKEGTDQELAKLRGQEAAQRTELKELQQTL 1074
Cdd:TIGR02168  184 TRENLDRLEDILNELERQL-KSLERQAekaERYKELKAELRELelallVLRLEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1075 EQLKIQLVKKEKEHPAGGASGEDASGpgtqsetagktdapgpELQALRAEISKLEQQCQQQQQQVEGLTHSLKseracra 1154
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQK----------------ELYALANEISRLEQQKQILRERLANLERQLE------- 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1155 EQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILN 1234
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1235 rqvlekegeskelKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQ 1314
Cdd:TIGR02168  400 -------------NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1315 AERAEELGQELKAWQEKFFQKEQ---ALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKrFREELEQSKQAAGG- 1390
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQArldSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGYEAAIEAALGg 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1391 -LQAELMR------------AQRELG-------------ELGSLRQKIVEQERAAQQLRAEKASYAEQLSM--------- 1435
Cdd:TIGR02168  546 rLQAVVVEnlnaakkaiaflKQNELGrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggv 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1436 -----LKKAHGLLAEENRGL-------------------GERANLGRQFLEVELDQAREKY------VQELAAVRTDAET 1485
Cdd:TIGR02168  626 lvvddLDNALELAKKLRPGYrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIeeleekIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1486 HLAEMRQEAQSTSRELEVMTAKYEGAKvkvlEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQ 1565
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALR----KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1566 QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELR 1645
Cdd:TIGR02168  782 AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2214681115 1646 SEAERLGRELQ---QAGLKTKEAEQTCRH--------LTAQVRSLEAQVAHADQQLRDLGK 1695
Cdd:TIGR02168  862 EELEELIEELEselEALLNERASLEEALAllrseleeLSEELRELESKRSELRRELEELRE 922
PTZ00121 PTZ00121
MAEBL; Provisional
 959-1666 2.45e-19

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 95.98  E-value: 2.45e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  959 REAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTlneQRVEFAALQEA 1038
Cdd:PTZ00121  1104 KKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEA---RKAEDAKKAEA 1180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1039 LAHALTEKEGTDQELAK-LRGQEAAQRTE----LKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAGKTDA 1113
Cdd:PTZ00121  1181 ARKAEEVRKAEELRKAEdARKAEAARKAEeerkAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEA 1260

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1114 PGPELQALRAEISKLEQQCQQQQQQVEgltHSLKSERACRAEQDKALETLQGQLEEKaRELGHNQAASASAQRELQALRA 1193
Cdd:PTZ00121  1261 RMAHFARRQAAIKAEEARKADELKKAE---EKKKADEAKKAEEKKKADEAKKKAEEA-KKADEAKKKAEEAKKKADAAKK 1336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1194 KAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRlvvAESEKSQKLEERLRLLQVETA 1273
Cdd:PTZ00121  1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK---ADEAKKKAEEDKKKADELKKA 1413

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1274 SNSARAAERSSALREEVQSLREEVEKQrvvsensrqELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALV 1353
Cdd:PTZ00121  1414 AAAKKKADEAKKKAEEKKKADEAKKKA---------EEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKK 1484

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1354 SELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRElgelgslRQKIVEQERAAQQLRAEKASYAEQL 1433
Cdd:PTZ00121  1485 ADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEE-------AKKADEAKKAEEKKKADELKKAEEL 1557

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1434 SmlKKAHGLLAEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRTDAETHLAEMRQEAqstsrelevmtakyEGAKV 1513
Cdd:PTZ00121  1558 K--KAEEKKKAEEAKKAEEDKNMALRKAE-EAKKAEEARIEEVMKLYEEEKKMKAEEAKKA--------------EEAKI 1620

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1514 KVlEERQRFQEERQKltaqVEQLEVFQREQTKQVEELSKKltEHDQASKVQQQKLKAFQAQRgesqqevqrlqtQLNELQ 1593
Cdd:PTZ00121  1621 KA-EELKKAEEEKKK----VEQLKKKEAEEKKKAEELKKA--EEENKIKAAEEAKKAEEDKK------------KAEEAK 1681

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2214681115 1594 AQLSQKEQAAEHYKLQMEKAKTHYDAKKqqnqKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAE 1666
Cdd:PTZ00121  1682 KAEEDEKKAAEALKKEAEEAKKAEELKK----KEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750
PTZ00121 PTZ00121
MAEBL; Provisional
 653-1432 3.12e-19

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 95.59  E-value: 3.12e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  653 IEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEE------KRRAADALKEQ 726
Cdd:PTZ00121  1052 IDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEArkaeeaKKKAEDARKAE 1131

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  727 QCRATEmeaESRSLMEQREREqkELEQEKAGRKGLEARiqQLEEAHQAEtEALRHELAEATASQHRAESecerlIREVES 806
Cdd:PTZ00121  1132 EARKAE---DARKAEEARKAE--DAKRVEIARKAEDAR--KAEEARKAE-DAKKAEAARKAEEVRKAEE-----LRKAED 1198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  807 RQKRFEARQQEEARYGAMFQEQLMALKGE--KTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQK 884
Cdd:PTZ00121  1199 ARKAEAARKAEEERKAEEARKAEDAKKAEavKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEAR 1278

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  885 LVDDLSALQEKMAATNKEvaclktlvlKAGEQQETASLELLKEPPRAANRASDQLGEQQGRpfssthaaVKAMEREAEQM 964
Cdd:PTZ00121  1279 KADELKKAEEKKKADEAK---------KAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKK--------ADAAKKKAEEA 1341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  965 GGELERLRAAliKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAkaelEMRLQNTLNEQRVEFAALQEALAHALT 1044
Cdd:PTZ00121  1342 KKAAEAAKAE--AEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAE----EKKKADEAKKKAEEDKKKADELKKAAA 1415

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1045 EKEGTDQelAKLRGQEAAQRTELKelQQTLEQLKIQLVKKEKEHpagGASGEDASGPGTQSETAGKTDAPGPELQALRAE 1124
Cdd:PTZ00121  1416 AKKKADE--AKKKAEEKKKADEAK--KKAEEAKKADEAKKKAEE---AKKAEEAKKKAEEAKKADEAKKKAEEAKKADEA 1488

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1125 ISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARElghnQAASASAQRELQALRaKAQDHSKAEEE 1204
Cdd:PTZ00121  1489 KKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKAD----EAKKAEEKKKADELK-KAEELKKAEEK 1563

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1205 WKAQVARgqQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQklEERLRLLQVETASNSARAAERSS 1284
Cdd:PTZ00121  1564 KKAEEAK--KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAE--EAKIKAEELKKAEEEKKKVEQLK 1639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1285 ALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQAL----VSELLPAK 1360
Cdd:PTZ00121  1640 KKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELkkkeAEEKKKAE 1719

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2214681115 1361 HLCQQLQAEQAAAEKRFREELEQSKQAAgglqaelmRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQ 1432
Cdd:PTZ00121  1720 ELKKAEEENKIKAEEAKKEAEEDKKKAE--------EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 519-1315 3.58e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 91.67  E-value: 3.58e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  519 KEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQ 598
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  599 QLETVEKEKDAK---LESLQQQLQAANdARDNAQTSVTQA--QQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQ 673
Cdd:TIGR02169  252 ELEKLTEEISELekrLEEIEQLLEELN-KKIKDLGEEEQLrvKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  674 LKAEQQKTTEREKVVQE----KAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEA----------ESRS 739
Cdd:TIGR02169  331 IDKLLAEIEELEREIEEerkrRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKlkreinelkrELDR 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  740 LMEQREREQKELEQEKAGRKGLEARIQQLE---EAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQ 816
Cdd:TIGR02169  411 LQEELQRLSEELADLNAAIAGIEAKINELEeekEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  817 EEARYGAmfqeQLMALKGEKTGQEVQEEAVEIHSEGQPGqQQSQLAQLHASLAKAIQQVQEKevRAQKLVDDLSALQEKM 896
Cdd:TIGR02169  491 ELAEAEA----QARASEERVRGGRAVEEVLKASIQGVHG-TVAQLGSVGERYATAIEVAAGN--RLNNVVVEDDAVAKEA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  897 AATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLG-EQQGRP-----FSSThAAVKAMEREAEQMGG-ELE 969
Cdd:TIGR02169  564 IELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEfDPKYEPafkyvFGDT-LVVEDIEAARRLMGKyRMV 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  970 RLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEmRLQNTLNEQRVEFAALQEALAHALTEKEGT 1049
Cdd:TIGR02169  643 TLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELS-SLQSELRRIENRLDELSQELSDASRKIGEI 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1050 DQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEhpaggasgedasgpgtQSETAGKTDAPGPELQALRAEISKLE 1129
Cdd:TIGR02169  722 EKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSE----------------LKELEARIEELEEDLHKLEEALNDLE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1130 qqCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQV 1209
Cdd:TIGR02169  786 --ARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKK 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1210 ARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREE 1289
Cdd:TIGR02169  864 EELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGED 943

                          810       820
                   ....*....|....*....|....*.
gi 2214681115 1290 VQSLREEVEKQRVVSENSRQELASQA 1315
Cdd:TIGR02169  944 EEIPEEELSLEDVQAELQRVEEEIRA 969
PTZ00121 PTZ00121
MAEBL; Provisional
 562-1324 5.46e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 91.36  E-value: 5.46e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  562 EEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARqqLETVEKEKDAKleSLQQQLQAANDARDNAQTSVTQAQQ---- 637
Cdd:PTZ00121  1094 EEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARK--AEEARKAEDAR--KAEEARKAEDAKRVEIARKAEDARKaeea 1169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  638 EKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKR 717
Cdd:PTZ00121  1170 RKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEER 1249

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  718 RAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEAR----IQQLEEAHQAETEALRHElaEATASQHRA 793
Cdd:PTZ00121  1250 NNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKkaeeKKKADEAKKKAEEAKKAD--EAKKKAEEA 1327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  794 ESECERLIREVESRQKRFEA-RQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAI 872
Cdd:PTZ00121  1328 KKKADAAKKKAEEAKKAAEAaKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKA 1407

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  873 QQVQEKEVRAQKlvddlsalQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGRPFSSTHA 952
Cdd:PTZ00121  1408 DELKKAAAAKKK--------ADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKA 1479

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  953 AVKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEF 1032
Cdd:PTZ00121  1480 EEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKK 1559

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1033 AALQEALAHALTEKEGTDQELAK---LRGQEAAQRTELKELQQTLEQLKIQLVKKEkehpaggasgEDASGPGTQSETAG 1109
Cdd:PTZ00121  1560 AEEKKKAEEAKKAEEDKNMALRKaeeAKKAEEARIEEVMKLYEEEKKMKAEEAKKA----------EEAKIKAEELKKAE 1629

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1110 KTDAPGPELQALRAEisklEQQCQQQQQQVEGLTHSLKSERACRAEQDKaletlqgqleEKARELghnQAASASAQRELQ 1189
Cdd:PTZ00121  1630 EEKKKVEQLKKKEAE----EKKKAEELKKAEEENKIKAAEEAKKAEEDK----------KKAEEA---KKAEEDEKKAAE 1692

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1190 ALRAKAQDHSKAEeewkaQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEErlrLLQ 1269
Cdd:PTZ00121  1693 ALKKEAEEAKKAE-----ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAH---LKK 1764

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2214681115 1270 VETASNSARAAERSSALREEVqslREEVEKQRVVSENSRQELASQAERAEELGQE 1324
Cdd:PTZ00121  1765 EEEKKAEEIRKEKEAVIEEEL---DEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 211-844 4.18e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.19  E-value: 4.18e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  211 QFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASSQEPS--------ELEELRGK 282
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELEsrleeleeQLETLRSK 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  283 NESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANH------------LQQLQGAFNDLIEEHSKAS 350
Cdd:TIGR02168  388 VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKelqaeleeleeeLEELQEELERLEEALEELR 467

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  351 QEWAEKQARL---ENELSTALQDKKCLEEKNEILQG----------KLSQLEDQATRLQESPAPEKG------EVLGDAL 411
Cdd:TIGR02168  468 EELEEAEQALdaaERELAQLQARLDSLERLQENLEGfsegvkallkNQSGLSGILGVLSELISVDEGyeaaieAALGGRL 547

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  412 Q-------------LDTLKQEAAKLATD---NTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSN 475
Cdd:TIGR02168  548 QavvvenlnaakkaIAFLKQNELGRVTFlplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLV 627

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  476 LSQAKEELEQASQAQGAQLTAQLT--------SMTG----LNATLQQRDQELASLKEQakkeQAQMLQTMQEQEQAAQGL 543
Cdd:TIGR02168  628 VDDLDNALELAKKLRPGYRIVTLDgdlvrpggVITGgsakTNSSILERRREIEELEEK----IEELEEKIAELEKALAEL 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  544 RQQVEQLSSSLKLKEQQLEEAAKEQEATRQDhAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAAND 623
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA 782

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  624 ARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQ-----------QKTTEREKVVQEKA 692
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATErrledleeqieELSEDIESLAAEIE 862

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  693 QLQEQLRALE---ESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLE 769
Cdd:TIGR02168  863 ELEELIEELEselEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  770 EAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRF--------EARQQEEARYGAMFQEQLMALKGEKTGQEV 841
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaiEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022


                   ...
gi 2214681115  842 QEE 844
Cdd:TIGR02168 1023 IEE 1025
PTZ00121 PTZ00121
MAEBL; Provisional
 343-1072 2.21e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 86.35  E-value: 2.21e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  343 IEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLedqATRLQESPAPEKGEVLGDALQLDTLKQEAAK 422
Cdd:PTZ00121  1111 AEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEI---ARKAEDARKAEEARKAEDAKKAEAARKAEEV 1187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  423 LATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQlasliadlqSSVSNLSQAKEELEQASQAQGAQLTAQLTSMT 502
Cdd:PTZ00121  1188 RKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKA---------EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFE 1258

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  503 GLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGL-RQQVEQLSSslKLKEQQLEEAAKEQEATRQDHAQQLAI 581
Cdd:PTZ00121  1259 EARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEeKKKADEAKK--KAEEAKKADEAKKKAEEAKKKADAAKK 1336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  582 VAE----AREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQtsvtqaQQEKAELSQKIGELHAciEASH 657
Cdd:PTZ00121  1337 KAEeakkAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAE------EKKKADEAKKKAEEDK--KKAD 1408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  658 QEQRQVQARVTELEAQLKAEQ-QKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAE 736
Cdd:PTZ00121  1409 ELKKAAAAKKKADEAKKKAEEkKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEA 1488

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  737 SRSLMEQREREQKELEQEKAGRKGLEAR----IQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFE 812
Cdd:PTZ00121  1489 KKKAEEAKKKADEAKKAAEAKKKADEAKkaeeAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEE 1568

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  813 ARQQEEARYGAMFQEQLMalkgeKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSAL 892
Cdd:PTZ00121  1569 AKKAEEDKNMALRKAEEA-----KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEA 1643

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  893 QEKMAATN----KEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLG--EQQGRPFSSTHAAVKAMEREAEQMGG 966
Cdd:PTZ00121  1644 EEKKKAEElkkaEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKkeAEEAKKAEELKKKEAEEKKKAEELKK 1723

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  967 ELE---------RLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVE------ 1031
Cdd:PTZ00121  1724 AEEenkikaeeaKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDkkikdi 1803

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 2214681115 1032 ---FAALQEA----LAHALTEKEGTDQELAKLRGQEAAQRTELKELQQ 1072
Cdd:PTZ00121  1804 fdnFANIIEGgkegNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEK 1851
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 954-1679 5.60e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 5.60e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  954 VKAMEREAEQMGGELERLRAA---LIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQ---NTLNE 1027
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRLEvseLEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEeleSKLDE 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1028 QRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEhpaggasgedasgpgtqset 1107
Cdd:TIGR02168  335 LAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQ-------------------- 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1108 agktdapgpeLQALRAEISKLEQQCQQQQQQVEGLTHSLKSERacRAEQDKALETLQGQLEEKARELGHNQAASASAQRE 1187
Cdd:TIGR02168  395 ----------IASLNNEIERLEARLERLEDRRERLQQEIEELL--KKLEEAELKELQAELEELEEELEELQEELERLEEA 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1188 LQALRAKAQDHSKAEEEWKAQVARGQQEAErksslissleeevsILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRL 1267
Cdd:TIGR02168  463 LEELREELEEAEQALDAAERELAQLQARLD--------------SLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEL 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1268 LQVETASNSARAAerssALREEVQSLreevekqrVVSENSRQELASQAERAEELGQ----ELKAWQEKFFQKEQALSALQ 1343
Cdd:TIGR02168  529 ISVDEGYEAAIEA----ALGGRLQAV--------VVENLNAAKKAIAFLKQNELGRvtflPLDSIKGTEIQGNDREILKN 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1344 LEHTSTQALVSELLPAK-HLCQQLQAEQAAAEKRFREELEQSKQAAGG-----LQAELMRAQ-RELGELGSLRQKIVEQE 1416
Cdd:TIGR02168  597 IEGFLGVAKDLVKFDPKlRKALSYLLGGVLVVDDLDNALELAKKLRPGyrivtLDGDLVRPGgVITGGSAKTNSSILERR 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1417 RAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRTDAEThLAEMRQEAQS 1496
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE-ELSRQISALRKDLARLEAEVEQ-LEERIAQLSK 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1497 TSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRG 1576
Cdd:TIGR02168  755 ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIA 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1577 ESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQ-----------DLEELQKENKELR 1645
Cdd:TIGR02168  835 ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAllrseleelseELRELESKRSELR 914

                          730       740       750
                   ....*....|....*....|....*....|....
gi 2214681115 1646 SEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSL 1679
Cdd:TIGR02168  915 RELEELREKLAQLELRLEGLEVRIDNLQERLSEE 948
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 244-885 2.27e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.34  E-value: 2.27e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  244 EKDAQIAMMQQRIDHLAL-LNEKQAASSQEPSELEELrGKNESLTVR-----LHETLKQCQN----LKTEKSQMDRKISQ 313
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKrLEEIEQLLEELNKKIKDL-GEEEQLRVKekigeLEAEIASLERsiaeKERELEDAEERLAK 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  314 LSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLEN---ELSTALQDKKCLEEKNEILQGKLSQLED 390
Cdd:TIGR02169  327 LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEvdkEFAETRDELKDYREKLEKLKREINELKR 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  391 QATRLQESPAPEKGEVLgdalqldTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQ 470
Cdd:TIGR02169  407 ELDRLQEELQRLSEELA-------DLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYD 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  471 SSVSNLSQAKEELEQASQAQGAQLTAQLTS-------------MTGLNATLQQRDQELASLKEQA--KKEQAQMLQTMQE 535
Cdd:TIGR02169  480 RVEKELSKLQRELAEAEAQARASEERVRGGraveevlkasiqgVHGTVAQLGSVGERYATAIEVAagNRLNNVVVEDDAV 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  536 QEQAAQGLR---------------QQVEQLSSSLKLK------------EQQLEEAAK---------EQEATRQDHAQQL 579
Cdd:TIGR02169  560 AKEAIELLKrrkagratflplnkmRDERRDLSILSEDgvigfavdlvefDPKYEPAFKyvfgdtlvvEDIEAARRLMGKY 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  580 --------------AIVAEAREASLRERDTARQQLEtvEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQK 645
Cdd:TIGR02169  640 rmvtlegelfeksgAMTGGSRAPRGGILFSRSEPAE--LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRK 717

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  646 IGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTT----EREKVVQEKAQLQEQLRALEESLKITKGSL--------E 713
Cdd:TIGR02169  718 IGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEnvksELKELEARIEELEEDLHKLEEALNDLEARLshsripeiQ 797

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  714 EEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARI---QQLEEAHQAETEALRHELAEATASQ 790
Cdd:TIGR02169  798 AELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIksiEKEIENLNGKKEELEEELEELEAAL 877

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  791 HRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEavEIHSEGQPGQQQSQLAQLHASLAK 870
Cdd:TIGR02169  878 RDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEE--ELSEIEDPKGEDEEIPEEELSLED 955

                          730
                   ....*....|....*
gi 2214681115  871 AIQQVQEKEVRAQKL 885
Cdd:TIGR02169  956 VQAELQRVEEEIRAL 970
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 646-1553 1.33e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.03  E-value: 1.33e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  646 IGELHACIEASHQEQRQVQARVTELEAQLKaeqQKTTEREKVVQEKAQLqEQLRALEESLKITKGSLEEEKRRAADALKE 725
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIID---EKRQQLERLRREREKA-ERYQALLKEKREYEGYELLKEKEALERQKE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  726 Q-QCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREV 804
Cdd:TIGR02169  241 AiERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  805 ESRQKRFEARQQEearygamFQEQLMALKGEKTGQEVQEEAVeihsegqpgqqQSQLAQLHASLAKAIQQVQEKEVRAQK 884
Cdd:TIGR02169  321 EERLAKLEAEIDK-------LLAEIEELEREIEEERKRRDKL-----------TEEYAELKEELEDLRAELEEVDKEFAE 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  885 LVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLkEPPRAANRASDQLGEQQgrpfssthAAVKAMEREAEQM 964
Cdd:TIGR02169  383 TRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELA-DLNAAIAGIEAKINELE--------EEKEDKALEIKKQ 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  965 GGELERLRAALIKsqgqqqeergqQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRvEFAALQEALAHALT 1044
Cdd:TIGR02169  454 EWKLEQLAADLSK-----------YEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVR-GGRAVEEVLKASIQ 521

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1045 EKEGTDQELAKLRGQ-----EAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGAS------GEDASGPGTQSETAGKTDa 1113
Cdd:TIGR02169  522 GVHGTVAQLGSVGERyataiEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATflplnkMRDERRDLSILSEDGVIG- 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1114 pgpelqaLRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKA-LETLQGQLEEKARELGHNQAASASAQRELQALR 1192
Cdd:TIGR02169  601 -------FAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYrMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEP 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1193 AKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVET 1272
Cdd:TIGR02169  674 AELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEI 753

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1273 ASNSA---RAAERSSALREEVQSLREEVEKqrVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTST 1349
Cdd:TIGR02169  754 ENVKSelkELEARIEELEEDLHKLEEALND--LEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1350 QALVSELLpakhlcqQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGS-----------LRQKIVEQERA 1418
Cdd:TIGR02169  832 EKEIQELQ-------EQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESrlgdlkkerdeLEAQLRELERK 904

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1419 AQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDqarekyvqelaavrtdaETHLAEMRQEAQSTS 1498
Cdd:TIGR02169  905 IEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS-----------------LEDVQAELQRVEEEI 967

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2214681115 1499 RELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLevfqREQTKQVEELSKK 1553
Cdd:TIGR02169  968 RALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAI----LERIEEYEKKKRE 1018
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1043-1693 1.91e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 76.26  E-value: 1.91e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1043 LTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDasgpgtqsETAGKTDAPGPELQALR 1122
Cdd:TIGR02169  229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKD--------LGEEEQLRVKEKIGELE 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1123 AEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAE 1202
Cdd:TIGR02169  301 AEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1203 EEWKAQVargqqeaerkssliSSLEEEVSILNRqvlekegESKELKRLVVAESEKSQKLEERLRLLQVETasnsARAAER 1282
Cdd:TIGR02169  381 AETRDEL--------------KDYREKLEKLKR-------EINELKRELDRLQEELQRLSEELADLNAAI----AGIEAK 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1283 SSALREEVQSLREEVEKQRvvsensrqelasqaERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKhl 1362
Cdd:TIGR02169  436 INELEEEKEDKALEIKKQE--------------WKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA-- 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1363 cqQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQR------ELGELGSLRQKIVEQERAAQQ----LRAEKASYAEQ 1432
Cdd:TIGR02169  500 --RASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGEryataiEVAAGNRLNNVVVEDDAVAKEaielLKRRKAGRATF 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1433 LSMLKKAHGLLaeENRGLGERANLGRQFLEVELDQARE---KYVQELAAVRTDAETHLAEMRQEAQSTsreLE------- 1502
Cdd:TIGR02169  578 LPLNKMRDERR--DLSILSEDGVIGFAVDLVEFDPKYEpafKYVFGDTLVVEDIEAARRLMGKYRMVT---LEgelfeks 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1503 -VMTAKY------EGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLtehdqasKVQQQKLKAFQAQR 1575
Cdd:TIGR02169  653 gAMTGGSraprggILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQEL-------SDASRKIGEIEKEI 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1576 GESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLE--ELQKENKELRSEAERLGR 1653
Cdd:TIGR02169  726 EQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEarLSHSRIPEIQAELSKLEE 805

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|
gi 2214681115 1654 ELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDL 1693
Cdd:TIGR02169  806 EVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDL 845
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 335-1324 2.21e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 76.26  E-value: 2.21e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  335 LQGAFNDLIEEHSKASQEWAEKQA---RLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPApekgevlgDAL 411
Cdd:TIGR02169  140 LQGDVTDFISMSPVERRKIIDEIAgvaEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRERE--------KAE 211

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  412 QLDTLKQEaaKLATDNTQLQTRVETLEcergKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQG 491
Cdd:TIGR02169  212 RYQALLKE--KREYEGYELLKEKEALE----RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLG 285

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  492 AQLTAQLTSmtglnatlqqrdqELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSslklKEQQLEEAAKEQEAT 571
Cdd:TIGR02169  286 EEEQLRVKE-------------KIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDK----LLAEIEELEREIEEE 348

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  572 RQDHAQQLAIVAEAREaslrERDTARQQLETVEKEKDA---KLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGE 648
Cdd:TIGR02169  349 RKRRDKLTEEYAELKE----ELEDLRAELEEVDKEFAEtrdELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD 424

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  649 LHACIEASHQEQRQVQARVTELEAQLKaeqQKTTEREKVVQEKAQLQEQLRALEESLKItkgsLEEEKRRAADALKEQQC 728
Cdd:TIGR02169  425 LNAAIAGIEAKINELEEEKEDKALEIK---KQEWKLEQLAADLSKYEQELYDLKEEYDR----VEKELSKLQRELAEAEA 497

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  729 RATEMEAESRSlmeqREREQKELEQEKAGRKGLEARIQQLEEAHQAETE-ALRHELAEATASQHRAESECERLIREVESR 807
Cdd:TIGR02169  498 QARASEERVRG----GRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEvAAGNRLNNVVVEDDAVAKEAIELLKRRKAG 573

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  808 QKRFEARQQeearygaMFQEQLMALKGEKTGqeVQEEAVEihsegqpgqqqsqLAQLHASLAKAIQQVqekeVRAQKLVD 887
Cdd:TIGR02169  574 RATFLPLNK-------MRDERRDLSILSEDG--VIGFAVD-------------LVEFDPKYEPAFKYV----FGDTLVVE 627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  888 DLSALQEKM-----------------AATNKEVACLKTLVLKAGEQQETASL-ELLKEPPRAANRASDQLGEQQGRPFSS 949
Cdd:TIGR02169  628 DIEAARRLMgkyrmvtlegelfeksgAMTGGSRAPRGGILFSRSEPAELQRLrERLEGLKRELSSLQSELRRIENRLDEL 707

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  950 THAAvkameREAEQMGGELERlraaliksqgqqqeergqqerevarltqERGQAQADLAQEKAAKAELEMRLQntlneqr 1029
Cdd:TIGR02169  708 SQEL-----SDASRKIGEIEK----------------------------EIEQLEQEEEKLKERLEELEEDLS------- 747

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1030 vefaALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEhpaggasgedasgpgTQSETAG 1109
Cdd:TIGR02169  748 ----SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS---------------KLEEEVS 808

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1110 KTDApgpELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQ 1189
Cdd:TIGR02169  809 RIEA---RLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG 885

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1190 ALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAE------SEKSQKLEE 1263
Cdd:TIGR02169  886 DLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsledvQAELQRVEE 965

                          970       980       990      1000      1010      1020
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2214681115 1264 RLRLLQvetaSNSARAAERSsalrEEVQSLREEVEKQRVVSENSRQELASQAERAEELGQE 1324
Cdd:TIGR02169  966 EIRALE----PVNMLAIQEY----EEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 774-1654 2.59e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.87  E-value: 2.59e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  774 AETEALRHELAEATASQHRAESecerLIREVESRQKRFEARQQEEARYgamfqeqlMALKGEKTGQEVQEEAVEIHS-EG 852
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDL----IIDEKRQQLERLRREREKAERY--------QALLKEKREYEGYELLKEKEAlER 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  853 QPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEK-MAATNKEVACLKTLVLKAgeqqeTASLELLKEPPRA 931
Cdd:TIGR02169  238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKiKDLGEEEQLRVKEKIGEL-----EAEIASLERSIAE 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  932 ANRASDQLGEQQGRPFSSTHAavkaMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEK 1011
Cdd:TIGR02169  313 KERELEDAEERLAKLEAEIDK----LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1012 AAKAELEMrLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQ-------QTLEQLKIQLVKK 1084
Cdd:TIGR02169  389 DYREKLEK-LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAleikkqeWKLEQLAADLSKY 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1085 EKEHpaggasgedasgpgtqSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGlthslksERACRAEQDKALETLQ 1164
Cdd:TIGR02169  468 EQEL----------------YDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRG-------GRAVEEVLKASIQGVH 524

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1165 GQLEEKAR-ELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQ------QEAERKSSLISSLEEEVSI---LN 1234
Cdd:TIGR02169  525 GTVAQLGSvGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRatflplNKMRDERRDLSILSEDGVIgfaVD 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1235 RQVLEKEGESKEL----KRLVVAESEKSQKLEERLRLLQVET-----------ASNSARAAE-RSSALREEVQSLREEVE 1298
Cdd:TIGR02169  605 LVEFDPKYEPAFKyvfgDTLVVEDIEAARRLMGKYRMVTLEGelfeksgamtgGSRAPRGGIlFSRSEPAELQRLRERLE 684

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1299 KQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFR 1378
Cdd:TIGR02169  685 GLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELE 764

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1379 EELEQSKQAAGGLQAELMRAQRELGelgslRQKIVEQERAAQQLRAEKASYAEQLSMLKkahgllAEENRGLGERANLgr 1458
Cdd:TIGR02169  765 ARIEELEEDLHKLEEALNDLEARLS-----HSRIPEIQAELSKLEEEVSRIEARLREIE------QKLNRLTLEKEYL-- 831

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1459 qfleveldqarEKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLE---ERQRFQEERQKLTAQVEQ 1535
Cdd:TIGR02169  832 -----------EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDlesRLGDLKKERDELEAQLRE 900

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1536 LEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTqLNELQAQLSQKEQAAEHYKLQMEKAKT 1615
Cdd:TIGR02169  901 LERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS-LEDVQAELQRVEEEIRALEPVNMLAIQ 979

                          890       900       910
                   ....*....|....*....|....*....|....*....
gi 2214681115 1616 HYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRE 1654
Cdd:TIGR02169  980 EYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1235-1703 2.95e-13

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 75.72  E-value: 2.95e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1235 RQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQ-VETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELAS 1313
Cdd:COG4913    241 HEALEDAREQIELLEPIRELAERYAAARERLAELEyLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDA 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1314 QAERAEEL--------GQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcqqlQAEQAAAEKRFREELEQSK 1385
Cdd:COG4913    321 LREELDELeaqirgngGDRLEQLEREIERLERELEERERRRARLEALLAAL----------GLPLPASAEEFAALRAEAA 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1386 QAAGGLQAELMRAQRELGELgslRQKIVEQERAAQQLRAEKAS-----------YAEQLSMLKKAHGLLAEENRGLGEra 1454
Cdd:COG4913    391 ALLEALEEELEALEEALAEA---EAALRDLRRELRELEAEIASlerrksniparLLALRDALAEALGLDEAELPFVGE-- 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1455 nlgrqFLEVELDQAR--------------------EKYVQELAAV-RTDAETHL------------AEMRQEAQSTSREL 1501
Cdd:COG4913    466 -----LIEVRPEEERwrgaiervlggfaltllvppEHYAAALRWVnRLHLRGRLvyervrtglpdpERPRLDPDSLAGKL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1502 EVMTAKYEGAKVKVLEERQRFqeerqkltAQVEQLEVFQRE--------QTKQveelSKKLTEHDQASKVQQQ------- 1566
Cdd:COG4913    541 DFKPHPFRAWLEAELGRRFDY--------VCVDSPEELRRHpraitragQVKG----NGTRHEKDDRRRIRSRyvlgfdn 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1567 --KLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQ--KLQEQLQDLEELQKENK 1642
Cdd:COG4913    609 raKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREiaELEAELERLDASSDDLA 688

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2214681115 1643 ELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDAL 1703
Cdd:COG4913    689 ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRA 749
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
243-750 4.52e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 75.08  E-value: 4.52e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  243 TEKDAQIAMMQQRIDHlALLNEKQAASSQEPSELEEL----------RGKNESLTVRLHETLKQCQNLKTEKSQMDRKIS 312
Cdd:PRK02224   190 DQLKAQIEEKEEKDLH-ERLNGLESELAELDEEIERYeeqreqaretRDEADEVLEEHEERREELETLEAEIEDLRETIA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  313 QLSEENGDLSFKVREFANHLQQLQGAFNDL----------IEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQ 382
Cdd:PRK02224   269 ETEREREELAEEVRDLRERLEELEEERDDLlaeaglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  383 GKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQL 462
Cdd:PRK02224   349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  463 ASLIADLQSSVSNLSQAKEELEQA--------------------SQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQA 522
Cdd:PRK02224   429 AELEATLRTARERVEEAEALLEAGkcpecgqpvegsphvetieeDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  523 K-----KEQAQMLQ--------TMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQdhaqqlaiVAEAREAS 589
Cdd:PRK02224   509 DrierlEERREDLEeliaerreTIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEARE--------EVAELNSK 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  590 LRERDTARQQLETVEkEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACI-EASHQEQRQVQARVT 668
Cdd:PRK02224   581 LAELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFdEARIEEAREDKERAE 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  669 ELEAQLKAE-QQKTTEREKVVQEKAQLQEQLRALEEsLKITKGSLeEEKRRAADALKEQQCRATEMEAESRSLMEQRERE 747
Cdd:PRK02224   660 EYLEQVEEKlDELREERDDLQAEIGAVENELEELEE-LRERREAL-ENRVEALEALYDEAEELESMYGDLRAELRQRNVE 737


                   ...
gi 2214681115  748 QKE 750
Cdd:PRK02224   738 TLE 740
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
537-1230 4.73e-13

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 74.95  E-value: 4.73e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  537 EQAAQGLRQQVEQLSSSlklkEQQLEEAAKeqeatRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDA-KLESLQ 615
Cdd:COG4913    224 FEAADALVEHFDDLERA----HEALEDARE-----QIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQrRLELLE 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  616 QQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHAcieashQEQRQVQARVTELEAQLKAEQQkttEREKVVQEKAQLQ 695
Cdd:COG4913    295 AELEELRAELARLEAELERLEARLDALREELDELEA------QIRGNGGDRLEQLEREIERLER---ELEERERRRARLE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  696 EQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEeahqAE 775
Cdd:COG4913    366 ALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIP----AR 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  776 TEALRHELAEATASqhrAESE----CErLIrEVESRQKRFEA------RQQE-----EARYGAMFQEqlmALKGEKTGQE 840
Cdd:COG4913    442 LLALRDALAEALGL---DEAElpfvGE-LI-EVRPEEERWRGaiervlGGFAltllvPPEHYAAALR---WVNRLHLRGR 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  841 VQEEAVEIHSEGQPGQQ---QSQLAQLHASLAKAIQQVQEKEVRAQKL--VDDLSAL-QEKMAATnkeVACLKTLVLKAG 914
Cdd:COG4913    514 LVYERVRTGLPDPERPRldpDSLAGKLDFKPHPFRAWLEAELGRRFDYvcVDSPEELrRHPRAIT---RAGQVKGNGTRH 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  915 EQQetaslellkepPRAANRASDQLGeqqgrpfSSTHAAVKAMEREAEQMGGELERLRAALikSQGQQQEERGQQEREVA 994
Cdd:COG4913    591 EKD-----------DRRRIRSRYVLG-------FDNRAKLAALEAELAELEEELAEAEERL--EALEAELDALQERREAL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  995 RLTQERGQAQADLAQEKAAKAELEMRLQNtLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTL 1074
Cdd:COG4913    651 QRLAEYSWDEIDVASAEREIAELEAELER-LDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEEL 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1075 EQLKIQLvkkekehpaggasgedasgpgtQSETAGKTDAPGPELQALRAEisklEQQCQQQQQQVEGLTHSLKSERACRA 1154
Cdd:COG4913    730 DELQDRL----------------------EAAEDLARLELRALLEERFAA----ALGDAVERELRENLEERIDALRARLN 783

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2214681115 1155 EQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHS--KAEEEWKAQVARgqQEAERKSSLISSLEEEV 1230
Cdd:COG4913    784 RAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDGlpEYEERFKELLNE--NSIEFVADLLSKLRRAI 859
HkD_SF cd22211
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ...
 8-136 2.39e-12

Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.


Pssm-ID: 411792  Cd Length: 145  Bit Score: 66.53  E-value: 2.39e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115    8 AATLLSWVNSLHVADPVETVLQLQDCSIFIKIINTI---HDTKEGQQILQQPLP-----ERLDFVCSFLQKNRKH----P 75
Cdd:cd22211      1 EAALLAWINTFPLSSPVESLDDLSDGVVLAEILSQIdpsYFDSEWLESRDSSDNwvlklNNLKKLYRSLSKYYREvlgqQ 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2214681115   76 SSTQCLVSVQKV-IEGSEMELAKMIMLFLYQSTMSSRNLRD---WEQFEYGVQAELAVILKFMLD 136
Cdd:cd22211     81 LSDLPLPDLSAIaRDGDEEEIVKLLELVLGAAVQCENKEEYiarIQQLDESTQAELMLIIQEVLE 145
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 512-1339 6.16e-12

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 71.54  E-value: 6.16e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  512 DQELASLKEQAKKEQAQmLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQlAIVAEAREASLR 591
Cdd:pfam02463  159 EEEAAGSRLKRKKKEAL-KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEE-YLLYLDYLKLNE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  592 ERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELhacIEASHQEQRQVQARVTELE 671
Cdd:pfam02463  237 ERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKE---EEELKSELLKLERRKVDDE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  672 AQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKEL 751
Cdd:pfam02463  314 EKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  752 EQEKAGRKGLEARIQqlEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMA 831
Cdd:pfam02463  394 EEELELKSEEEKEAQ--LLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  832 LKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEK-----------------EVRAQKLVDDLSALQE 894
Cdd:pfam02463  472 DLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDgvggriisahgrlgdlgVAVENYKVAISTAVIV 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  895 KMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGRPF--SSTHAAVKAMEREAEQMGGELERLR 972
Cdd:pfam02463  552 EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNlaQLDKATLEADEDDKRAKVVEGILKD 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  973 AALIKSQGQQQEERGQQEREVARL-----TQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKE 1047
Cdd:pfam02463  632 TELTKLKESAKAKESGLRKGVSLEeglaeKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1048 GTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEhpagGASGEDASGPGTQSETAGKTDAPGPELQALRAEISK 1127
Cdd:pfam02463  712 LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEE----EEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLK 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1128 LEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKA 1207
Cdd:pfam02463  788 VEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEE 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1208 QVARG------QQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAE 1281
Cdd:pfam02463  868 LLQELllkeeeLEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADE 947

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2214681115 1282 RSSA------LREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQAL 1339
Cdd:pfam02463  948 KEKEennkeeEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAI 1011
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1176-1722 7.44e-12

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 71.10  E-value: 7.44e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1176 HNQAASASAQRE-LQALRAKAQDHSKAEEEwkaqvaRGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAE 1254
Cdd:COG4913    241 HEALEDAREQIElLEPIRELAERYAAARER------LAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1255 SEKSQKLEERLRLLQVETASNSARAAERssaLREEVQSLREEVEKQRVVSEN--------------SRQELASQ----AE 1316
Cdd:COG4913    315 EARLDALREELDELEAQIRGNGGDRLEQ---LEREIERLERELEERERRRARleallaalglplpaSAEEFAALraeaAA 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1317 RAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL------LPAKHLcqqlqaeqaaaekRFREELEqskQAAGG 1390
Cdd:COG4913    392 LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLerrksnIPARLL-------------ALRDALA---EALGL 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1391 LQAEL--------MRAQREL------GELGSLRQKI-VEQERAAQQLRaekasYAEQLSMLKKAHGLLAEENRGLGERAN 1455
Cdd:COG4913    456 DEAELpfvgelieVRPEEERwrgaieRVLGGFALTLlVPPEHYAAALR-----WVNRLHLRGRLVYERVRTGLPDPERPR 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1456 LGRQFL----EVELDQAREkYVQELAAVRTDAE--THLAEMRQEAQ--------STSRELEVMTAKYEGAKVKVL----- 1516
Cdd:COG4913    531 LDPDSLagklDFKPHPFRA-WLEAELGRRFDYVcvDSPEELRRHPRaitragqvKGNGTRHEKDDRRRIRSRYVLgfdnr 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1517 EERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRgesqqEVQRLQTQLNELQA-- 1594
Cdd:COG4913    610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAER-----EIAELEAELERLDAss 684

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1595 -QLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLT 1673
Cdd:COG4913    685 dDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVE 764

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2214681115 1674 AQVR-SLEAQVAHADQQLRDL-GKFQVATDALKSREPQVKPQLDLSIDSLD 1722
Cdd:COG4913    765 RELReNLEERIDALRARLNRAeEELERAMRAFNREWPAETADLDADLESLP 815
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 450-648 9.06e-12

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 71.02  E-value: 9.06e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  450 AERSRFEDEKQQLASLIADLQSSVSNLSQAKeeLEQASQAQGAQL-------TAQLTSMT-GLNAtLQQRDQELASLKEQ 521
Cdd:NF012221  1569 ADRQRLEQEKQQQLAAISGSQSQLESTDQNA--LETNGQAQRDAIleesravTKELTTLAqGLDA-LDSQATYAGESGDQ 1645

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  522 AKKEQAQ-MLQTMQEQ-EQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQ-----QLAIVAEAREASLRERD 594
Cdd:NF012221  1646 WRNPFAGgLLDRVQEQlDDAKKISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQGEQnqanaEQDIDDAKADAEKRKDD 1725

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2214681115  595 TARQQLETVEKEKDAKLESLQQQLQAANDARdNAQTSVTQAQQEKAELSQKIGE 648
Cdd:NF012221  1726 ALAKQNEAQQAESDANAAANDAQSRGEQDAS-AAENKANQAQADAKGAKQDESD 1778
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 381-960 1.00e-11

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 70.64  E-value: 1.00e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  381 LQGKLSQLEDQATRLQESpapeKGEVLGDALQLDTLKQEAA--------KLATDNTQLQTRVETLECERGKQEAQLLAER 452
Cdd:pfam12128  246 LQQEFNTLESAELRLSHL----HFGYKSDETLIASRQEERQetsaelnqLLRTLDDQWKEKRDELNGELSAADAAVAKDR 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  453 SRFED-EKQQLASLIADLQSSVSNLSQA---KEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQ 528
Cdd:pfam12128  322 SELEAlEDQHGAFLDADIETAAADQEQLpswQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAK 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  529 MLQTMQEQEQAAQG--------LRQQVEQLSSSLKLKEQQLEEAAKEqEATRQDHAQQLAIVAEAREASLRERDTARQQL 600
Cdd:pfam12128  402 IREARDRQLAVAEDdlqaleseLREQLEAGKLEFNEEEYRLKSRLGE-LKLRLNQATATPELLLQLENFDERIERAREEQ 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  601 EtvekEKDAKLESLQQQLQAANDARDNA-------QTSVTQAQQEKAELSQ----KIGELHACIEASHQEQRQVQARVTE 669
Cdd:pfam12128  481 E----AANAEVERLQSELRQARKRRDQAsealrqaSRRLEERQSALDELELqlfpQAGTLLHFLRKEAPDWEQSIGKVIS 556

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  670 LEAQLKAEQQKTTEREKVVQEKAQLQEQLRaLEESLKITKGSLEEEKRRAADALKE----QQCRATEMEAESRSLMEQRE 745
Cdd:pfam12128  557 PELLHRTDLDPEVWDGSVGGELNLYGVKLD-LKRIDVPEWAASEEELRERLDKAEEalqsAREKQAAAEEQLVQANGELE 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  746 REQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAM- 824
Cdd:pfam12128  636 KASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTe 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  825 FQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVA 904
Cdd:pfam12128  716 KQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVL 795

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2214681115  905 CLKTLvlkageQQETASLE--LLKEPPRAANRASDQLGEQQGRPFSSTHAAVKAMERE 960
Cdd:pfam12128  796 RYFDW------YQETWLQRrpRLATQLSNIERAISELQQQLARLIADTKLRRAKLEME 847
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1466-1707 1.24e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.35  E-value: 1.24e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1466 DQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLevfqREQTK 1545
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE----YELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1546 QVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKthyDAKKQQNQ 1625
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE---EALLEAEA 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1626 KLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKS 1705
Cdd:COG1196    373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452


                   ..
gi 2214681115 1706 RE 1707
Cdd:COG1196    453 EL 454
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 213-814 1.57e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.10  E-value: 1.57e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  213 QMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLAllnekqaassqepSELEELRGKNESLTVRLHE 292
Cdd:TIGR02169  288 EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLL-------------AEIEELEREIEEERKRRDK 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  293 TLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSK---ASQEWAEKQARLENELSTALQ 369
Cdd:TIGR02169  355 LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRlqeELQRLSEELADLNAAIAGIEA 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  370 DKKCLEEKNEILQGKLSQLEDQATRLQEspapekgevlgdalQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLL 449
Cdd:TIGR02169  435 KINELEEEKEDKALEIKKQEWKLEQLAA--------------DLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQAR 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  450 AERSRFEDEKQQLASLIADLQS---SVSNLSQAKEELEQASQ-AQGAQLTA--------------QLTSMTGLNAT---- 507
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKASIQGvhgTVAQLGSVGERYATAIEvAAGNRLNNvvveddavakeaieLLKRRKAGRATflpl 580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  508 --LQQRDQELASLKEQAKKEQAQMLQTMQEQEQAA--------------------------------------------- 540
Cdd:TIGR02169  581 nkMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAfkyvfgdtlvvedieaarrlmgkyrmvtlegelfeksgamtggsr 660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  541 ---------QGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQdHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKL 611
Cdd:TIGR02169  661 aprggilfsRSEPAELQRLRERLEGLKRELSSLQSELRRIEN-RLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERL 739

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  612 ESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEA-----SHQEQRQVQ--------------ARVTELEA 672
Cdd:TIGR02169  740 EELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlearlSHSRIPEIQaelskleeevsrieARLREIEQ 819

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  673 QLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELE 752
Cdd:TIGR02169  820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLR 899

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2214681115  753 QEKAGRKGLEARIQQLEEaHQAETEALRHELAEATASQHRA------ESECERLIREVESRQKRFEAR 814
Cdd:TIGR02169  900 ELERKIEELEAQIEKKRK-RLSELKAKLEALEEELSEIEDPkgedeeIPEEELSLEDVQAELQRVEEE 966
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
324-803 2.18e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 69.56  E-value: 2.18e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  324 KVREFANHLQQLQGAFNDLIEEHSKASQ-----------EWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQA 392
Cdd:COG4913    246 DAREQIELLEPIRELAERYAAARERLAEleylraalrlwFAQRRLELLEAELEELRAELARLEAELERLEARLDALREEL 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  393 TRLQESPAPEKGEVLGD-ALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQS 471
Cdd:COG4913    326 DELEAQIRGNGGDRLEQlEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEE 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  472 SVSNLSQAKEELEQASQaqgaQLTAQLTSMTGLNATLQQRDQEL-ASLKEQAKKEQAQM-----LQTMQEQEQAAQG--- 542
Cdd:COG4913    406 ALAEAEAALRDLRRELR----ELEAEIASLERRKSNIPARLLALrDALAEALGLDEAELpfvgeLIEVRPEEERWRGaie 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  543 --LRQQ-----------------VEQLSSSLKLKEQQLEEAAKEQEATRQDH---AQQLAI----VAEAREASLRER--- 593
Cdd:COG4913    482 rvLGGFaltllvppehyaaalrwVNRLHLRGRLVYERVRTGLPDPERPRLDPdslAGKLDFkphpFRAWLEAELGRRfdy 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  594 ---DTArQQLETVEK---------------EKD----------------AKLESLQQQLQAANDARDNAQTSVTQAQQEK 639
Cdd:COG4913    562 vcvDSP-EELRRHPRaitragqvkgngtrhEKDdrrrirsryvlgfdnrAKLAALEAELAELEEELAEAEERLEALEAEL 640

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  640 AELSQKIGELHACIEASHQEQ--RQVQARVTELEAQLKAE-------QQKTTEREKVVQEKAQLQEQLRALEEslkiTKG 710
Cdd:COG4913    641 DALQERREALQRLAEYSWDEIdvASAEREIAELEAELERLdassddlAALEEQLEELEAELEELEEELDELKG----EIG 716

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  711 SLEEEKRRAADALKEQQCRATEMEAESRSLMEQRereqkeleqekagrkgLEARIQQL--EEAHQAETEALRHELAEATA 788
Cdd:COG4913    717 RLEKELEQAEEELDELQDRLEAAEDLARLELRAL----------------LEERFAAAlgDAVERELRENLEERIDALRA 780

                          570
                   ....*....|....*
gi 2214681115  789 SQHRAESECERLIRE 803
Cdd:COG4913    781 RLNRAEEELERAMRA 795
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1378-1683 5.21e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.17  E-value: 5.21e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1378 REELEQSKQAAGGLQAELMRAQRE--LGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAhgllaEENRGLGERAN 1455
Cdd:TIGR02169  217 LKEKREYEGYELLKEKEALERQKEaiERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKK-----IKDLGEEEQLR 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1456 LGRQFLEVELDQAREKyvqelaavrtDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQ 1535
Cdd:TIGR02169  292 VKEKIGELEAEIASLE----------RSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1536 LEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKT 1615
Cdd:TIGR02169  362 LKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEE 441

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2214681115 1616 HYDAK----KQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQV 1683
Cdd:TIGR02169  442 EKEDKaleiKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVE 513
PTZ00121 PTZ00121
MAEBL; Provisional
 1144-1667 6.33e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.24  E-value: 6.33e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1144 HSLKSERACRAEQDKALETLQGQLEEKARElgHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLI 1223
Cdd:PTZ00121  1056 HEGKAEAKAHVGQDEGLKPSYKDFDFDAKE--DNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEA 1133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1224 SSLEEEVSIlnrqvlEKEGESKELKRLVVA-ESEKSQKLEERLRLLQVETASNSARAAERSSAlrEEVQSLRE--EVEKQ 1300
Cdd:PTZ00121  1134 RKAEDARKA------EEARKAEDAKRVEIArKAEDARKAEEARKAEDAKKAEAARKAEEVRKA--EELRKAEDarKAEAA 1205

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1301 RVVSENSRQELASQAERAEELgQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHlcQQLQAEQAAAEKRFREE 1380
Cdd:PTZ00121  1206 RKAEEERKAEEARKAEDAKKA-EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHF--ARRQAAIKAEEARKADE 1282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1381 LEQSKQAAgglQAELMRAQRELGELGSLRQKiVEQERAAQQLRAEKASYAEQLSMLKKAhgllAEENRGLGERAnlgrqf 1460
Cdd:PTZ00121  1283 LKKAEEKK---KADEAKKAEEKKKADEAKKK-AEEAKKADEAKKKAEEAKKKADAAKKK----AEEAKKAAEAA------ 1348

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1461 leveldqarekyvqelaavrtdaethlaemRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKltaqveqlevfq 1540
Cdd:PTZ00121  1349 ------------------------------KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK------------ 1386

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1541 REQTKQVEELSKKLTEHDQasKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAK 1620
Cdd:PTZ00121  1387 AEEKKKADEAKKKAEEDKK--KADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1621 KQQNQKLQEQLQDLEELQKENKELRSEAERLGR---ELQQAGLKTKEAEQ 1667
Cdd:PTZ00121  1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKkadEAKKAAEAKKKADE 1514
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 872-1691 8.71e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.79  E-value: 8.71e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  872 IQQVQEKEVRAQKLVDDLSALQEKMAaTNKEVAcLKTLVLKAgEQQETASLELLKEppRAANRASDQLGEQQgrpFSSTH 951
Cdd:TIGR02169  179 LEEVEENIERLDLIIDEKRQQLERLR-REREKA-ERYQALLK-EKREYEGYELLKE--KEALERQKEAIERQ---LASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  952 AAVKAMEREAEQMGGELERLRAALiksQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVE 1031
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLL---EELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1032 FAALQEALAhaltEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASgedasgpgtQSETAGKT 1111
Cdd:TIGR02169  328 EAEIDKLLA----EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE---------LKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1112 DAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQAL 1191
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDL 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1192 RAKAQDHSKAEEEWKAQVARG---QQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSqkLEERLRLL 1268
Cdd:TIGR02169  475 KEEYDRVEKELSKLQRELAEAeaqARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVA--AGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1269 QVETASNSARAAE---RSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQL- 1344
Cdd:TIGR02169  553 VVEDDAVAKEAIEllkRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAa 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1345 -EHTSTQALVS---ELLPAKHLCQQLQAEQAAAEKRFREELEQSKQaaggLQAELMRAQRELGelgSLRQKIVEQERAAQ 1420
Cdd:TIGR02169  633 rRLMGKYRMVTlegELFEKSGAMTGGSRAPRGGILFSRSEPAELQR----LRERLEGLKRELS---SLQSELRRIENRLD 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1421 QLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRTDaethLAEMRQEAQSTSRE 1500
Cdd:TIGR02169  706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS-SLEQEIENVKSELKELEAR----IEELEEDLHKLEEA 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1501 LEVMTAKYEGAKVKVLEERQRFQEE-RQKLTAQVEQLEvfqreqtkqveelskkltehdqaskvqqQKLKAFQAQRGESQ 1579
Cdd:TIGR02169  781 LNDLEARLSHSRIPEIQAELSKLEEeVSRIEARLREIE----------------------------QKLNRLTLEKEYLE 832

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1580 QEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKakthydaKKQQNQKLQEQLQDLEE----LQKENKELRSEAERLGREL 1655
Cdd:TIGR02169  833 KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEE-------LEEELEELEAALRDLESrlgdLKKERDELEAQLRELERKI 905

                          810       820       830
                   ....*....|....*....|....*....|....*.
gi 2214681115 1656 QQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLR 1691
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKG 941
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 292-771 9.75e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 66.97  E-value: 9.75e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  292 ETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENeLSTALQDK 371
Cdd:TIGR04523  135 ENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSN-LKKKIQKN 213

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  372 KCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKlatDNTQLQTRVETLE------CERGKQE 445
Cdd:TIGR04523  214 KSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNK---IKKQLSEKQKELEqnnkkiKELEKQL 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  446 AQLLAERSRFEDEKQQ--LASLIADLQSSVSNLSQAKEELEQASQA------QGAQLTAQLTSMTGLNATLQQRDQELAS 517
Cdd:TIGR04523  291 NQLKSEISDLNNQKEQdwNKELKSELKNQEKKLEEIQNQISQNNKIisqlneQISQLKKELTNSESENSEKQRELEEKQN 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  518 LKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEARE--ASLRERDT 595
Cdd:TIGR04523  371 EIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSeiKDLTNQDS 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  596 ArqqLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQE--------------KAELSQKIGELHACIEASHQEQR 661
Cdd:TIGR04523  451 V---KELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKElkskekelkklneeKKELEEKVKDLTKKISSLKEKIE 527

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  662 QVQARVTELE---AQLKAEQQKTTEREKVVQEKAQLQEQLRALEEsLKITKGSLEEEKRRAADALKEQQCRATEMEAESR 738
Cdd:TIGR04523  528 KLESEKKEKEskiSDLEDELNKDDFELKKENLEKEIDEKNKEIEE-LKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIE 606

                          490       500       510
                   ....*....|....*....|....*....|...
gi 2214681115  739 SLMEQREREQKELEQEKAGRKGLEARIQQLEEA 771
Cdd:TIGR04523  607 EKEKKISSLEKELEKAKKENEKLSSIIKNIKSK 639
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 300-891 1.80e-10

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 66.40  E-value: 1.80e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  300 LKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNE 379
Cdd:pfam12128  246 LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELE 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  380 ILQGKLSQLED---QATRLQESPAP----------EKGEVLGDALQLDTLKQEAAKLATDnTQLQTRVETLECERGKQ-- 444
Cdd:pfam12128  326 ALEDQHGAFLDadiETAAADQEQLPswqselenleERLKALTGKHQDVTAKYNRRRSKIK-EQNNRDIAGIKDKLAKIre 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  445 --------------------EAQLLAERSRFEDEKQQLASLIADLQ----------SSVSNLSQAKEELEQASQAQGAQL 494
Cdd:pfam12128  405 ardrqlavaeddlqaleselREQLEAGKLEFNEEEYRLKSRLGELKlrlnqatatpELLLQLENFDERIERAREEQEAAN 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  495 TAQLTSMTGLNATLQQRDQELASLK--EQAKKEQAQMLQTMQEQ------------EQAAQGLRQQVEQLSSSLKLKEQQ 560
Cdd:pfam12128  485 AEVERLQSELRQARKRRDQASEALRqaSRRLEERQSALDELELQlfpqagtllhflRKEAPDWEQSIGKVISPELLHRTD 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  561 LE----EAAKEQEAT----RQDHAQQLAIVAEAREASLRERdtaRQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSV 632
Cdd:pfam12128  565 LDpevwDGSVGGELNlygvKLDLKRIDVPEWAASEEELRER---LDKAEEALQSAREKQAAAEEQLVQANGELEKASREE 641

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  633 TQAQQ--EKAELS------QKIGELHACIEASHQEQRQVQARVTELEAQLKA---------EQQKTTEREKVVQEKAQLQ 695
Cdd:pfam12128  642 TFARTalKNARLDlrrlfdEKQSEKDKKNKALAERKDSANERLNSLEAQLKQldkkhqawlEEQKEQKREARTEKQAYWQ 721

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  696 E---QLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQ--EKAGRKGLEAR--IQQL 768
Cdd:pfam12128  722 VvegALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERkiERIAVRRQEVLryFDWY 801

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  769 EEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTG-QEVQEEAVE 847
Cdd:pfam12128  802 QETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKlATLKEDANS 881

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....
gi 2214681115  848 IHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSA 891
Cdd:pfam12128  882 EQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHFKNVIADHSG 925
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
216-851 3.54e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.47  E-value: 3.54e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  216 RLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLAL----LNEKQAASSQEPSELEELRGKNESLTVRLH 291
Cdd:PRK03918   169 EVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSelpeLREELEKLEKEVKELEELKEEIEELEKELE 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  292 ETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFaNHLQQLQGAFNDLIEEHSkasqEWAEKQARLENELSTALQDK 371
Cdd:PRK03918   249 SLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKEL-KELKEKAEEYIKLSEFYE----EYLDELREIEKRLSRLEEEI 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  372 KCLEEKNEILQGKLSQLEDQATRLQESpAPEKGEVLGDALQLDTLKQEAAKLatdnTQLQTRVETLECERGKQEAQLLAE 451
Cdd:PRK03918   324 NGIEERIKELEEKEERLEELKKKLKEL-EKRLEELEERHELYEEAKAKKEEL----ERLKKRLTGLTPEKLEKELEELEK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  452 R-SRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQ---AQGAQLTAQ-----LTSMTGLNATLQQRDQELASLKEQA 522
Cdd:PRK03918   399 AkEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGkcpVCGRELTEEhrkelLEEYTAELKRIEKELKEIEEKERKL 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  523 KKEQAQmLQTMQEQEQAAQGLRQQVEQLSS-SLKLKEQQLEEAAKEqeatrqdhaqqlaivAEAREASLRERDTARQQLE 601
Cdd:PRK03918   479 RKELRE-LEKVLKKESELIKLKELAEQLKElEEKLKKYNLEELEKK---------------AEEYEKLKEKLIKLKGEIK 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  602 TVEKEKDaKLESLQQQLQAANDARDNaqtsvtqAQQEKAELSQKIGEL-HACIEashqeqrQVQARVTELEAQLKaeqqK 680
Cdd:PRK03918   543 SLKKELE-KLEELKKKLAELEKKLDE-------LEEELAELLKELEELgFESVE-------ELEERLKELEPFYN----E 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  681 TTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQcratemEAESRSLMEQREREQKELEQEKAGRKG 760
Cdd:PRK03918   604 YLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELE------ELEKKYSEEEYEELREEYLELSRELAG 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  761 LEARIQQLEEaHQAETEALRHELAEATASQHRAESECERLirevESRQKRFEARQQEEARYGAMFQEQLMalkgektgQE 840
Cdd:PRK03918   678 LRAELEELEK-RREEIKKTLEKLKEELEEREKAKKELEKL----EKALERVEELREKVKKYKALLKERAL--------SK 744

                          650
                   ....*....|.
gi 2214681115  841 VQEEAVEIHSE 851
Cdd:PRK03918   745 VGEIASEIFEE 755
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 605-813 5.06e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 63.63  E-value: 5.06e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  605 KEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTER 684
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  685 ekvvqeKAQLQEQLRALEESLKITK--------------------GSLEEEKRRAADALKEQQCRATEMEAESRSLMEQR 744
Cdd:COG4942    103 ------KEELAELLRALYRLGRQPPlalllspedfldavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115  745 EREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEA 813
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
429-820 6.55e-10

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 64.40  E-value: 6.55e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  429 QLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQAsQAQGAQLTAQLTSMTGLNAtL 508
Cdd:COG4717     50 RLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEEL-EAELEELREELEKLEKLLQ-L 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  509 QQRDQELASLKEQAKKEQAQmLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREA 588
Cdd:COG4717    128 LPLYQELEALEAELAELPER-LEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQ 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  589 SLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT-----------SVTQAQQEKAELSQKIGELHACIEASH 657
Cdd:COG4717    207 RLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEArlllliaaallALLGLGGSLLSLILTIAGVLFLVLGLL 286

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  658 QEQRQVQARVTELEAQLKAEQQKTTEREKVvqEKAQLQEQLRALEESLKITKGSLEEEKRRAADAlkeQQCRATEMEAES 737
Cdd:COG4717    287 ALLFLLLAREKASLGKEAEELQALPALEEL--EEEELEELLAALGLPPDLSPEELLELLDRIEEL---QELLREAEELEE 361

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  738 RSLMEQREREQKELEQEK--AGRKGLEARIQQLEEAHQAETE--ALRHELAE---------ATASQHRAESECERLIREV 804
Cdd:COG4717    362 ELQLEELEQEIAALLAEAgvEDEEELRAALEQAEEYQELKEEleELEEQLEEllgeleellEALDEEELEEELEELEEEL 441

                          410
                   ....*....|....*.
gi 2214681115  805 ESRQKRFEARQQEEAR 820
Cdd:COG4717    442 EELEEELEELREELAE 457
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 998-1695 8.78e-10

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 64.20  E-value: 8.78e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  998 QERGQAQADLAQE--KAAKAELEmRLQNTLNEQRVEFAALQEAL-----AHALTEK-----EGTDQELAKLRGQEAAQRT 1065
Cdd:COG3096    377 LAEAEARLEAAEEevDSLKSQLA-DYQQALDVQQTRAIQYQQAVqalekARALCGLpdltpENAEDYLAAFRAKEQQATE 455

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1066 ELKELQQTLEQLKI---------QLVKKekehPAGGASGEDASGPGTQS-ETAGKTDAPGPELQALRAEISKLEQQCQQQ 1135
Cdd:COG3096    456 EVLELEQKLSVADAarrqfekayELVCK----IAGEVERSQAWQTARELlRRYRSQQALAQRLQQLRAQLAELEQRLRQQ 531

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1136 QQQV---EGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEW-KAQVAR 1211
Cdd:COG3096    532 QNAErllEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWlAAQDAL 611

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1212 GQQEAERKSSLISSleEEVSILNRQVLEKEGESKELKRLVVaesEKSQKLEERLRLLQVETASNSAR------------- 1278
Cdd:COG3096    612 ERLREQSGEALADS--QEVTAAMQQLLEREREATVERDELA---ARKQALESQIERLSQPGGAEDPRllalaerlggvll 686

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1279 -----------AAERS---------------SALREEVQSL-----------------------REEVEKQRVVSENSRQ 1309
Cdd:COG3096    687 seiyddvtledAPYFSalygparhaivvpdlSAVKEQLAGLedcpedlyliegdpdsfddsvfdAEELEDAVVVKLSDRQ 766

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1310 -------EL-----ASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVsellpAKHLCQQlqaeqaaaekrF 1377
Cdd:COG3096    767 wrysrfpEVplfgrAAREKRLEELRAERDELAEQYAKASFDVQKLQRLHQAFSQFV-----GGHLAVA-----------F 830

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1378 REELEQSKQAaggLQAELMRAQRELgelgslrqkiVEQERAAQQLRAEKASYAEQLSMLKKAHG---LLAEEnrGLGERa 1454
Cdd:COG3096    831 APDPEAELAA---LRQRRSELEREL----------AQHRAQEQQLRQQLDQLKEQLQLLNKLLPqanLLADE--TLADR- 894

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1455 nlgRQFLEVELDQARE--KYVQELAAVRTDAETHLAEMRQEAQStsreLEVMTAKYEGAKvkvleerqrfqEERQKLTAQ 1532
Cdd:COG3096    895 ---LEELREELDAAQEaqAFIQQHGKALAQLEPLVAVLQSDPEQ----FEQLQADYLQAK-----------EQQRRLKQQ 956

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1533 VEQL-EVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQkeqaaehyklqme 1611
Cdd:COG3096    957 IFALsEVVQRRPHFSYEDAVGLLGENSDLNEKLRARLEQAEEARREAREQLRQAQAQYSQYNQVLAS------------- 1023

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1612 kAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERlgRELQQAGLKTKeaeQTCRHLTAQVRSLEAQVAHADQQLR 1691
Cdd:COG3096   1024 -LKSSRDAKQQTLQELEQELEELGVQADAEAEERARIRR--DELHEELSQNR---SRRSQLEKQLTRCEAEMDSLQKRLR 1097


                   ....
gi 2214681115 1692 DLGK 1695
Cdd:COG3096   1098 KAER 1101
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
458-1077 9.27e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.17  E-value: 9.27e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  458 EKQQLASLIADLQSSVSNLSQAKEELEQASQaqgaqltaQLTSMTGLNATLQQRDQELASLKEQakkEQAQMLQTMQEQE 537
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHEALEDARE--------QIELLEPIRELAERYAAARERLAEL---EYLRAALRLWFAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  538 QAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQqlaIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQ 617
Cdd:COG4913    288 RRLELLEAELEELRAELARLEAELERLEARLDALREELDE---LEAQIRGNGGDRLEQLEREIERLERELEERERRRARL 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  618 LQAANDARdnaqtsvTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQqktterekvvQEKAQLQEQ 697
Cdd:COG4913    365 EALLAALG-------LPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR----------RELRELEAE 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  698 LRALEESlkitKGSLEEEKRRAADALKEqQCRATEME----AEsrsLMEQREREQK------------------ELEQEK 755
Cdd:COG4913    428 IASLERR----KSNIPARLLALRDALAE-ALGLDEAElpfvGE---LIEVRPEEERwrgaiervlggfaltllvPPEHYA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  756 AGRKGLEARiqQLEEAHQAEtealrhELAEATASQHRAESECERLIREVESRQKRFEA--RQQEEARYGAMFQEQLMALK 833
Cdd:COG4913    500 AALRWVNRL--HLRGRLVYE------RVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAwlEAELGRRFDYVCVDSPEELR 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  834 GE-----KTGQEVQEEAVEIHSEGQPGQQQSQLAQlhaslaKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKT 908
Cdd:COG4913    572 RHpraitRAGQVKGNGTRHEKDDRRRIRSRYVLGF------DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  909 LVLKAGEQQETASLELLKeppRAANRASDQLGEQQGRpFSSTHAAVKAMEREAEQMGGELERLRAALiksqgqqqeergq 988
Cdd:COG4913    646 RREALQRLAEYSWDEIDV---ASAEREIAELEAELER-LDASSDDLAALEEQLEELEAELEELEEEL------------- 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  989 qerevARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELK 1068
Cdd:COG4913    709 -----DELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLN 783


                   ....*....
gi 2214681115 1069 ELQQTLEQL 1077
Cdd:COG4913    784 RAEEELERA 792
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 327-701 1.38e-09

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 63.82  E-value: 1.38e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  327 EFANHLQQLQGAFNDLIEEHSKASqEW----------AEKQARLENELStALQDKkcLEEKNEILQGKLSQLEDQATRLQ 396
Cdd:COG3096    310 EMARELEELSARESDLEQDYQAAS-DHlnlvqtalrqQEKIERYQEDLE-ELTER--LEEQEEVVEEAAEQLAEAEARLE 385

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  397 ESPApekgEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLE-CERGKQEAQLLAER-----SRFEDEKQQLASLIADLQ 470
Cdd:COG3096    386 AAEE----EVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEkARALCGLPDLTPENaedylAAFRAKEQQATEEVLELE 461

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  471 SSVSNLSQAKEELEQASQAqgaqltaqLTSMTGlnatlqqrdqelASLKEQAKKEQAQMLQTMQEQEQAAQglrqQVEQL 550
Cdd:COG3096    462 QKLSVADAARRQFEKAYEL--------VCKIAG------------EVERSQAWQTARELLRRYRSQQALAQ----RLQQL 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  551 ssslklkEQQLEEAakEQEATRQDHAQQLAivaEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT 630
Cdd:COG3096    518 -------RAQLAEL--EQRLRQQQNAERLL---EEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQ 585

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2214681115  631 SVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEA-------QLKAEQQKTTEREKVVQEKAQLQEQLRAL 701
Cdd:COG3096    586 QLEQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQEvtaamqqLLEREREATVERDELAARKQALESQIERL 663
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 508-927 2.54e-09

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 62.89  E-value: 2.54e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  508 LQQRDQELASLKEQAKKEQAQMLQ-------------TMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEA---T 571
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKElekkhqqlceeknALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESrleE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  572 RQDHAQQLAIVAEAR-------EASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQ 644
Cdd:pfam01576   87 EEERSQQLQNEKKKMqqhiqdlEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTS 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  645 KIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQ----EKAQLQEQ---LRALEESLKITKGSLEEEKR 717
Cdd:pfam01576  167 NLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRklegESTDLQEQiaeLQAQIAELRAQLAKKEEELQ 246

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  718 RAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEahqaETEALRHELAE---ATASQH--- 791
Cdd:pfam01576  247 AALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGE----ELEALKTELEDtldTTAAQQelr 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  792 -RAESECERLIREVESRQKRFEARQQEEARYGAM----FQEQLMALKG-----EKTGQEVQEEAVEIHSEGQPGQQQSQl 861
Cdd:pfam01576  323 sKREQEVTELKKALEEETRSHEAQLQEMRQKHTQaleeLTEQLEQAKRnkanlEKAKQALESENAELQAELRTLQQAKQ- 401

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2214681115  862 aQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVlkagEQQETASLELLKE 927
Cdd:pfam01576  402 -DSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLL----NEAEGKNIKLSKD 462
mukB PRK04863
chromosome partition protein MukB;
441-1356 3.43e-09

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 62.28  E-value: 3.43e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  441 RGKQEAQLLAERSRFEDEKQQLAS--LIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNAtLQQRDQELASL 518
Cdd:PRK04863   282 RVHLEEALELRRELYTSRRQLAAEqyRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEK-IERYQADLEEL 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  519 KEQAKkEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLK---------LKEQQLEEAAKEQEATRQDHAQQLAIVAEAREAS 589
Cdd:PRK04863   361 EERLE-EQNEVVEEADEQQEENEARAEAAEEEVDELKsqladyqqaLDVQQTRAIQYQQAVQALERAKQLCGLPDLTADN 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  590 LRERdtaRQQLETVEKEKDAKLESLQQQL---QAANDARDNAQTSVTQA--QQEKAELSQKIGELhaciEASHQEQRQVQ 664
Cdd:PRK04863   440 AEDW---LEEFQAKEQEATEELLSLEQKLsvaQAAHSQFEQAYQLVRKIagEVSRSEAWDVAREL----LRRLREQRHLA 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  665 ARVTELEAQLKaeqqkttEREKVVQEKAQLQEQLRALEESLKITKGSLEEekrrAADALKEQQCRATEMEAESRSLMEQR 744
Cdd:PRK04863   513 EQLQQLRMRLS-------ELEQRLRQQQRAERLLAEFCKRLGKNLDDEDE----LEQLQEELEARLESLSESVSEARERR 581

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  745 EREQKELEQEKAGRKGLEARIQQLEEAHQA---------ETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQ 815
Cdd:PRK04863   582 MALRQQLEQLQARIQRLAARAPAWLAAQDAlarlreqsgEEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEI 661

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  816 QEEARYGAMFQEQLMALKGEKTGQEVQE--EAVEIHSEGqpgqqqsQLAQLHASLAKAIqqvqekevraqkLVDDLSALQ 893
Cdd:PRK04863   662 ERLSQPGGSEDPRLNALAERFGGVLLSEiyDDVSLEDAP-------YFSALYGPARHAI------------VVPDLSDAA 722

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  894 EKMAAtnkEVACLKTLVLKAGEQQETAS----LELLkeppraANRASDQLGEQQGRpfSSTHAAVKAMEREAEqmggelE 969
Cdd:PRK04863   723 EQLAG---LEDCPEDLYLIEGDPDSFDDsvfsVEEL------EKAVVVKIADRQWR--YSRFPEVPLFGRAAR------E 785

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  970 RLRAALiksqgqqqeergqqerevarltqergQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHAltekEGT 1049
Cdd:PRK04863   786 KRIEQL--------------------------RAEREELAERYATLSFDVQKLQRLHQAFSRFIGSHLAVAFE----ADP 835

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1050 DQELAKLRGQEAAQRTELKELQQTLEQLKIQLvKKEKEHPAGgasgedasgpgtqsetagktdapgpeLQALRAEISKLE 1129
Cdd:PRK04863   836 EAELRQLNRRRVELERALADHESQEQQQRSQL-EQAKEGLSA--------------------------LNRLLPRLNLLA 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1130 qqcqqqqqqVEGLTHSLkseRACRAEQDKAletlqgqlEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQV 1209
Cdd:PRK04863   889 ---------DETLADRV---EEIREQLDEA--------EEAKRFVQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQ 948

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1210 ARGQQEAERKSSLIS--------SLEEEVSILNRqvlEKEGESKELKRLVVAESEKSQkLEERLRLLQVETASNSARAAE 1281
Cdd:PRK04863   949 QTQRDAKQQAFALTEvvqrrahfSYEDAAEMLAK---NSDLNEKLRQRLEQAEQERTR-AREQLRQAQAQLAQYNQVLAS 1024

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2214681115 1282 ---RSSALREEVQSLREEVEKQRVVSENSRQELAsqAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1356
Cdd:PRK04863  1025 lksSYDAKRQMLQELKQELQDLGVPADSGAEERA--RARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKL 1100
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 546-1345 4.20e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.91  E-value: 4.20e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  546 QVEQLSSSLKLKEQQLEEAAKEqeatrqdhAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQqlqaANDAR 625
Cdd:pfam02463  143 KIEIIAMMKPERRLEIEEEAAG--------SRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQ----AKKAL 210

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  626 DNAQTSvtQAQQEKAELSQKIGELHACIEASHQEQRQVQARVtELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESL 705
Cdd:pfam02463  211 EYYQLK--EKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQ-EEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEE 287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  706 KITKGSLEEEKRRAADALKEQQCRATEMEAESrslmeqrEREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAE 785
Cdd:pfam02463  288 LKLLAKEEEELKSELLKLERRKVDDEEKLKES-------EKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEE 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  786 ATASQHRAESECERLIREVESRQKRFEARQQEearygamfQEQLMALKGEKtGQEVQEeaveihsegqpgqqQSQLAQLH 865
Cdd:pfam02463  361 LEKLQEKLEQLEEELLAKKKLESERLSSAAKL--------KEEELELKSEE-EKEAQL--------------LLELARQL 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  866 ASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEpprAANRASDQLGEQQGR 945
Cdd:pfam02463  418 EDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL---VKLQEQLELLLSRQK 494

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  946 PFSSTHAAVKAMEREA-EQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNT 1024
Cdd:pfam02463  495 LEERSQKESKARSGLKvLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELP 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1025 LNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTQ 1104
Cdd:pfam02463  575 LGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSL 654

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1105 SETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASA 1184
Cdd:pfam02463  655 EEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKI 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1185 QRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEER 1264
Cdd:pfam02463  735 NEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEA 814

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1265 LRLLQVETASNSARAAERSSALREEVQSLrEEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQL 1344
Cdd:pfam02463  815 ELLEEEQLLIEQEEKIKEEELEELALELK-EEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEE 893


                   .
gi 2214681115 1345 E 1345
Cdd:pfam02463  894 K 894
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1202-1695 4.24e-09

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 62.05  E-value: 4.24e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1202 EEEWKAQVARGQQEAERKSSlissleEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRllqvETASNSARAAE 1281
Cdd:pfam05483  103 QKENKLQENRKIIEAQRKAI------QELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLK----ETCARSAEKTK 172

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1282 RSSALREEVQSLREEV-----------EKQRVVSENSRQELASQAERAEELGQEL-KAWQEKFFQKEQALSALQLEHTST 1349
Cdd:pfam05483  173 KYEYEREETRQVYMDLnnniekmilafEELRVQAENARLEMHFKLKEDHEKIQHLeEEYKKEINDKEKQVSLLLIQITEK 252

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1350 QALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAEL----MRAQRELGELGSLRQKIVEQERAAQQLRAE 1425
Cdd:pfam05483  253 ENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELedikMSLQRSMSTQKALEEDLQIATKTICQLTEE 332

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1426 KASYAEQLSMLKKAHGLLAEENRG----LGERANLGRQFLEVELDQarekyVQELAAVRTDAETHLAEMRQEAQSTSREL 1501
Cdd:pfam05483  333 KEAQMEELNKAKAAHSFVVTEFEAttcsLEELLRTEQQRLEKNEDQ-----LKIITMELQKKSSELEEMTKFKNNKEVEL 407

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1502 EVMTaKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQE 1581
Cdd:pfam05483  408 EELK-KILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLK 486

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1582 VQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQkenKELRSEAERLGRELQQAGLK 1661
Cdd:pfam05483  487 NIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKE---MNLRDELESVREEFIQKGDE 563

                          490       500       510
                   ....*....|....*....|....*....|....*...
gi 2214681115 1662 TK----EAEQTCRHLTAQVRSLEAQVAHADQQLRDLGK 1695
Cdd:pfam05483  564 VKckldKSEENARSIEYEVLKKEKQMKILENKCNNLKK 601
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1375-1697 4.90e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.00  E-value: 4.90e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1375 KRFREELEQSKQAAGGLQAelMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGllaeenrglgera 1454
Cdd:TIGR02168  213 ERYKELKAELRELELALLV--LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVS------------- 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1455 nlgrqflevELDQAREKYVQELAAVRTDaethLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVE 1534
Cdd:TIGR02168  278 ---------ELEEEIEELQKELYALANE----ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1535 QLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAK 1614
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1615 THydAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLG 1694
Cdd:TIGR02168  425 EL--LKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE 502


                   ...
gi 2214681115 1695 KFQ 1697
Cdd:TIGR02168  503 GFS 505
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 509-816 6.34e-09

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 61.29  E-value: 6.34e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  509 QQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDH-AQQLAIVAEARE 587
Cdd:pfam17380  303 QEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEiAMEISRMRELER 382

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  588 ASL---RERDTARQQLETVEKEKdakLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQ 664
Cdd:pfam17380  383 LQMerqQKNERVRQELEAARKVK---ILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQ 459

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  665 ARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRaleeslKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQR 744
Cdd:pfam17380  460 QQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRR------KILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEE 533

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2214681115  745 EREqkELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEatasqhrAESECERLIREVESRQKRFEARQQ 816
Cdd:pfam17380  534 RRR--EAEEERRKQQEMEERRRIQEQMRKATEERSRLEAME-------REREMMRQIVESEKARAEYEATTP 596
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
412-974 8.47e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.08  E-value: 8.47e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  412 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSrfEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQG 491
Cdd:COG4913    256 PIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAEL--EELRAELARLEAELERLEARLDALREELDELEAQIR 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  492 AQLTAQLtsmtglnatlqqrdqelaslkEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAT 571
Cdd:COG4913    334 GNGGDRL---------------------EQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  572 RQDHAQQLAIVAEAREASLRERDTARQQLETVEKEkdakLESLQQQlqaandardnaQTSVTQAQQE-KAELSQK----- 645
Cdd:COG4913    393 LEALEEELEALEEALAEAEAALRDLRRELRELEAE----IASLERR-----------KSNIPARLLAlRDALAEAlglde 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  646 -----IGELhacIEASHQEQR--------------------QVQARVTELEAQLKAEQQKTTERekvVQEKAQLQEQLRA 700
Cdd:COG4913    458 aelpfVGEL---IEVRPEEERwrgaiervlggfaltllvppEHYAAALRWVNRLHLRGRLVYER---VRTGLPDPERPRL 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  701 LEESL--KIT------KGSLEEEKRRAADALKeqqCR-ATEMEAESRSLMEQREREQKELEQEKAGRKGLEAR------- 764
Cdd:COG4913    532 DPDSLagKLDfkphpfRAWLEAELGRRFDYVC---VDsPEELRRHPRAITRAGQVKGNGTRHEKDDRRRIRSRyvlgfdn 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  765 IQQLeeahqaetEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEarygAMFQEQLMALKGEKTGQEVQEE 844
Cdd:COG4913    609 RAKL--------AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLA----EYSWDEIDVASAEREIAELEAE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  845 AVEIHSEgqpgqqQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLEL 924
Cdd:COG4913    677 LERLDAS------SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL 750

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|
gi 2214681115  925 LKEppRAANRASDQLGEQQGRPFSSTHAAVKAMEREAEQmggELERLRAA 974
Cdd:COG4913    751 LEE--RFAAALGDAVERELRENLEERIDALRARLNRAEE---ELERAMRA 795
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 332-809 8.65e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 60.90  E-value: 8.65e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  332 LQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEK----NEILQGKLSQLEDQATRLQES--------- 398
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQarnqNSMYMRQLSDLESTVSQLRSElreakrmye 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  399 ---PAPEKGEVLGDAlQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERS---RFEDEKQQLASLIADLQSS 472
Cdd:pfam15921  342 dkiEELEKQLVLANS-ELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEqnkRLWDRDTGNSITIDHLRRE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  473 VSNLSQAKEELEQ-----ASQAQGaQLTAQLTSMTGLNATLQQRDQELASLkEQAKKEQAQMLQTMQEQEQAAQGLRQQV 547
Cdd:pfam15921  421 LDDRNMEVQRLEAllkamKSECQG-QMERQMAAIQGKNESLEKVSSLTAQL-ESTKEMLRKVVEELTAKKMTLESSERTV 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  548 EQLSSSLKLKEQQLEEAAKE--QEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDAR 625
Cdd:pfam15921  499 SDLTASLQEKERAIEATNAEitKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLV 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  626 DNAQTSVTQAQQEKAELSQKIG-------ELHACIEASHQEQRQVQARVTELEAQ-----------LKAEQQKTTEREKV 687
Cdd:pfam15921  579 GQHGRTAGAMQVEKAQLEKEINdrrlelqEFKILKDKKDAKIRELEARVSDLELEkvklvnagserLRAVKDIKQERDQL 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  688 VQEKAQLQEQLRALEESLKITKGSLE---EEKRRAADALKEQQCRATEMEAESRSLMEQRERE-----------QKELEQ 753
Cdd:pfam15921  659 LNEVKTSRNELNSLSEDYEVLKRNFRnksEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSdghamkvamgmQKQITA 738

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2214681115  754 EKAGRKGLEARIQQLEEAH----------QAETEALRHELAEATASQHRAESECErLIREVESRQK 809
Cdd:pfam15921  739 KRGQIDALQSKIQFLEEAMtnankekhflKEEKNKLSQELSTVATEKNKMAGELE-VLRSQERRLK 803
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 463-681 1.37e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.39  E-value: 1.37e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  463 ASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQG 542
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  543 LRQQVEQLSSSLKlKEQQLEEAAKEQEATRQDHAQQLAI-------VAEAREASLRERDTARQQLETVEKEKDAKLESLQ 615
Cdd:COG4942     99 LEAQKEELAELLR-ALYRLGRQPPLALLLSPEDFLDAVRrlqylkyLAPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2214681115  616 QQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKT 681
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1117-1650 1.55e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.08  E-value: 1.55e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1117 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALEtlqgQLEEKARELGHNQAaSASAQRELQALRAKAQ 1196
Cdd:PRK03918   232 ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIE----ELEEKVKELKELKE-KAEEYIKLSEFYEEYL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1197 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSilnrqvlEKEGESKELKRlVVAESEKSQKLEERLRLLQVETASNS 1276
Cdd:PRK03918   307 DELREIEKRLSRLEEEINGIEERIKELEEKEERLE-------ELKKKLKELEK-RLEELEERHELYEEAKAKKEELERLK 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1277 ARAAERSSalrEEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALvsEL 1356
Cdd:PRK03918   379 KRLTGLTP---EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRK--EL 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1357 LPAKHLcqqLQAEQAAAEKRFREELEQSKQAAGGLQAELMRaQRELGELGSLRQKIVEQERAAQQLRAEKASY-AEQLSM 1435
Cdd:PRK03918   454 LEEYTA---ELKRIEKELKEIEEKERKLRKELRELEKVLKK-ESELIKLKELAEQLKELEEKLKKYNLEELEKkAEEYEK 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1436 LKKAHGLLAEENRGLGERANLGRQF------LEVELDQAREkyvqELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYE 1509
Cdd:PRK03918   530 LKEKLIKLKGEIKSLKKELEKLEELkkklaeLEKKLDELEE----ELAELLKELEELGFESVEELEERLKELEPFYNEYL 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1510 GAKvKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQasKVQQQKLKAFQAQRGESQQEVQRLQTQL 1589
Cdd:PRK03918   606 ELK-DAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEK--KYSEEEYEELREEYLELSRELAGLRAEL 682

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2214681115 1590 NELQAQLSQKEQAAEHYKLQMEKAKThydaKKQQNQKLQEQLQDLEELQKENKELRSEAER 1650
Cdd:PRK03918   683 EELEKRREEIKKTLEKLKEELEEREK----AKKELEKLEKALERVEELREKVKKYKALLKE 739
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1517-1727 2.33e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.69  E-value: 2.33e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1517 EERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQL 1596
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1597 SQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGL----KTKEAEQTCRHL 1672
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLEtlrsKVAQLELQIASL 398

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2214681115 1673 TAQVRSLEAQVAHADQQLRDLGkfQVATDALKSREPQVKPQLDLSIDSLDLSLEE 1727
Cdd:TIGR02168  399 NNEIERLEARLERLEDRRERLQ--QEIEELLKKLEEAELKELQAELEELEEELEE 451
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1117-1595 2.37e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.54  E-value: 2.37e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1117 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERacRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1196
Cdd:COG4913    256 PIRELAERYAAARERLAELEYLRAALRLWFAQRR--LELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIR 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1197 DHS-KAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASN 1275
Cdd:COG4913    334 GNGgDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAA 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1276 SARAAERSSALREEVQSLREeveKQRVVSENS---RQELASQAERAE----------ELGQELKAWQ------------- 1329
Cdd:COG4913    414 LRDLRRELRELEAEIASLER---RKSNIPARLlalRDALAEALGLDEaelpfvgeliEVRPEEERWRgaiervlggfalt 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1330 ----EKFFQkeQALSALQLEHTSTQaLVSELLPAKHlcqQLQAEQAAAEKRFREELEQSKQAAGG-LQAEL--------- 1395
Cdd:COG4913    491 llvpPEHYA--AALRWVNRLHLRGR-LVYERVRTGL---PDPERPRLDPDSLAGKLDFKPHPFRAwLEAELgrrfdyvcv 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1396 ------------------MRAQRELGELG-------------SLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLA 1444
Cdd:COG4913    565 dspeelrrhpraitragqVKGNGTRHEKDdrrrirsryvlgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQ 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1445 EENRGLGERANLgrQFLEVELDQAREKYV---QELAAVRTD------AETHLAEMRQEAQSTSRELEVMTAKYEGAKvkv 1515
Cdd:COG4913    645 ERREALQRLAEY--SWDEIDVASAEREIAeleAELERLDASsddlaaLEEQLEELEAELEELEEELDELKGEIGRLE--- 719

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1516 lEERQRFQEERQKLTAQVEQLEvfQREQTKQVEELSKKLTEHDQAsKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQ 1595
Cdd:COG4913    720 -KELEQAEEELDELQDRLEAAE--DLARLELRALLEERFAAALGD-AVERELRENLEERIDALRARLNRAEEELERAMRA 795
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1158-1680 2.38e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.31  E-value: 2.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1158 KALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSL---ISSLEEEVSILN 1234
Cdd:PRK03918   186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLegsKRKLEEKIRELE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1235 RQVLEKEGESKELKRLV--VAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEkqrvvsensrqELA 1312
Cdd:PRK03918   266 ERIEELKKEIEELEEKVkeLKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIK-----------ELE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1313 SQAERAEELGQELKAWQEKffqkeqaLSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQaagglq 1392
Cdd:PRK03918   335 EKEERLEELKKKLKELEKR-------LEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKE------ 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1393 aELMRAQREL-GELGSLRQKIVEQERAAQQLRAEK-------------------ASYAEQLSMLKKAHGLLAEENRGLGE 1452
Cdd:PRK03918   402 -EIEEEISKItARIGELKKEIKELKKAIEELKKAKgkcpvcgrelteehrkellEEYTAELKRIEKELKEIEEKERKLRK 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1453 RANLGRQFLEVELDQAREKYV-QELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTA 1531
Cdd:PRK03918   481 ELRELEKVLKKESELIKLKELaEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAE 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1532 QVEQLEVFQREQT-----------KQVEELSKKLTEHDQASKvQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKE 1600
Cdd:PRK03918   561 LEKKLDELEEELAellkeleelgfESVEELEERLKELEPFYN-EYLELKDAEKELEREEKELKKLEEELDKAFEELAETE 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1601 QAAEHYKLQMEKAKTHYDAKkqqnqklqeqlqDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLE 1680
Cdd:PRK03918   640 KRLEELRKELEELEKKYSEE------------EYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
798-1331 2.89e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.28  E-value: 2.89e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  798 ERLIREVESRQKRFEArqQEEARYGAMFQEQLMALKgektgQEVQEEAVEI-HSEGQPGQQQSQLAQLHASLAKAIQQVQ 876
Cdd:PRK02224   179 ERVLSDQRGSLDQLKA--QIEEKEEKDLHERLNGLE-----SELAELDEEIeRYEEQREQARETRDEADEVLEEHEERRE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  877 EKEVraqkLVDDLSALQEKMAATNKEVACLKTLVlkagEQQETASLELLKEppRAANRASDQLGEQQGrpfSSTHAAVKA 956
Cdd:PRK02224   252 ELET----LEAEIEDLRETIAETEREREELAEEV----RDLRERLEELEEE--RDDLLAEAGLDDADA---EAVEARREE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  957 MEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRlQNTLNEQRVEFAALQ 1036
Cdd:PRK02224   319 LEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDR-REEIEELEEEIEELR 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1037 EALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAG-----GASGEDASGPGTQSETAGKT 1111
Cdd:PRK02224   398 ERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGkcpecGQPVEGSPHVETIEEDRERV 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1112 DAPGPELQALRAEISKLEqqcqqqqqqveglthslksERACRAEQDKALETLQGQLEEKAR---ELGHNQAASASAQRE- 1187
Cdd:PRK02224   478 EELEAELEDLEEEVEEVE-------------------ERLERAEDLVEAEDRIERLEERREdleELIAERRETIEEKREr 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1188 LQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEvsilnRQVLEKEGESKELKRLVVAESEKSQKLEERLRL 1267
Cdd:PRK02224   539 AEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSK-----LAELKERIESLERIRTLLAAIADAEDEIERLRE 613

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2214681115 1268 LQVETASNSARAAERSSALREEVQSLREEVEKQRVvsENSRQELASQAERAEELGQELKAWQEK 1331
Cdd:PRK02224   614 KREALAELNDERRERLAEKRERKRELEAEFDEARI--EEAREDKERAEEYLEQVEEKLDELREE 675
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 252-817 2.89e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 59.42  E-value: 2.89e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  252 MQQRIDHLALLNEKQAASSQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKIS----QLSEENGDLSFKVRE 327
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAarkqELEEILHELESRLEE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  328 FANHLQQLQGafndlieEHSKASQEWAEKQARLENELST--ALQ-DKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKG 404
Cdd:pfam01576   87 EEERSQQLQN-------EKKKMQQHIQDLEEQLDEEEAArqKLQlEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  405 EVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQllaeRSRFEDEKQQLASLIADLQSSVSNLSQAKEELE 484
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKG----RQELEKAKRKLEGESTDLQEQIAELQAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  485 QASQAQGAQLTAQLTSM---TGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLklkEQQL 561
Cdd:pfam01576  236 AQLAKKEEELQAALARLeeeTAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL---EDTL 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  562 EEAAKEQEATRQDHAQqlaiVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAE 641
Cdd:pfam01576  313 DTTAAQQELRSKREQE----VTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAE 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  642 LSQKIGELHACIEASHQEQRQVQARVTELEAQL-KAEQQKTTEREKVVQEKAQLQEQLRALEE----SLKITK--GSLEE 714
Cdd:pfam01576  389 LQAELRTLQQAKQDSEHKRKKLEGQLQELQARLsESERQRAELAEKLSKLQSELESVSSLLNEaegkNIKLSKdvSSLES 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  715 EKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLeeahQAETEALRHELAEATASQHRAE 794
Cdd:pfam01576  469 QLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTL----QAQLSDMKKKLEEDAGTLEALE 544

                          570       580
                   ....*....|....*....|...
gi 2214681115  795 SECERLIREVESRQKRFEARQQE 817
Cdd:pfam01576  545 EGKKRLQRELEALTQQLEEKAAA 567
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 274-698 3.49e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 58.88  E-value: 3.49e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  274 SELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGD----LSFKVREFANHLQQLQGAFNDLIEEHSKA 349
Cdd:TIGR04523  218 SQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKikkqLSEKQKELEQNNKKIKELEKQLNQLKSEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  350 SQEWAEKQARLENELSTAL--QDKKCLEEKNEILQG--KLSQLEDQATRLQ------ESPAPEKGEVLGDAL-QLDTLKQ 418
Cdd:TIGR04523  298 SDLNNQKEQDWNKELKSELknQEKKLEEIQNQISQNnkIISQLNEQISQLKkeltnsESENSEKQRELEEKQnEIEKLKK 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  419 EAAKLATDNTQLQTRVETLECERGKQEAQ----------LLAERSRFEDEKQQLASLIADLQSSVSNLSQAK-------E 481
Cdd:TIGR04523  378 ENQSYKQEIKNLESQINDLESKIQNQEKLnqqkdeqikkLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDsvkeliiK 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  482 ELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELaslkeqakKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQL 561
Cdd:TIGR04523  458 NLDNTRESLETQLKVLSRSINKIKQNLEQKQKEL--------KSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  562 EEAAKEQEatrqdhaqqLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAE 641
Cdd:TIGR04523  530 ESEKKEKE---------SKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKD 600

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2214681115  642 LSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKtteREKVVQEKAQLQEQL 698
Cdd:TIGR04523  601 LIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSK---KNKLKQEVKQIKETI 654
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 305-675 4.81e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.54  E-value: 4.81e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  305 SQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGK 384
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  385 LSQLEDQATRLQESpAPEKGEVLGDALQ-LDTLKQEAAKLATDNT-QLQTRVETLECERGKQEAQLLAErsrfEDEKQQL 462
Cdd:TIGR02169  246 LASLEEELEKLTEE-ISELEKRLEEIEQlLEELNKKIKDLGEEEQlRVKEKIGELEAEIASLERSIAEK----ERELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  463 ASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAqltsmtgLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQG 542
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEEERKRRDK-------LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  543 LRQQVEQLsSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKekdaKLESLQQQLQAAN 622
Cdd:TIGR02169  394 LEKLKREI-NELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEW----KLEQLAADLSKYE 468

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2214681115  623 DARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLK 675
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQ 521
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1520-1742 8.49e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.76  E-value: 8.49e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1520 QRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQK 1599
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1600 EQAAEHYKLQMEKAKTHYDAKK----QQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQ 1675
Cdd:TIGR02168  301 EQQKQILRERLANLERQLEELEaqleELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2214681115 1676 VRSLEAQVAHADQQLRDLGKFQVATDALKSREPQVKPQLDLSIDSLDLSLEEGTPCSVASKLPRTQP 1742
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEE 447
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 262-864 8.61e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 57.42  E-value: 8.61e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  262 LNEKQAASSQEPSELEELRGKNESLTVRLHETLKQCQNL-----------------------KTEKSQMDRKIS------ 312
Cdd:pfam05483  108 LQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLikennatrhlcnllketcarsaeKTKKYEYEREETrqvymd 187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  313 -----------------QLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQ----EWAEKQARLEN--------- 362
Cdd:pfam05483  188 lnnniekmilafeelrvQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSllliQITEKENKMKDltflleesr 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  363 ------ELSTALQDKKcLEEKNEILQGKLSQLEDQATRLQESPAPEKgeVLGDALQL------------DTLKQEAAKLA 424
Cdd:pfam05483  268 dkanqlEEKTKLQDEN-LKELIEKKDHLTKELEDIKMSLQRSMSTQK--ALEEDLQIatkticqlteekEAQMEELNKAK 344

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  425 TDNTQLQTRVETLECergKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLsqakEELEQASQAQGAQLtAQLTSMTGL 504
Cdd:pfam05483  345 AAHSFVVTEFEATTC---SLEELLRTEQQRLEKNEDQLKIITMELQKKSSEL----EEMTKFKNNKEVEL-EELKKILAE 416

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  505 NATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEatrQDHAQQLAIVAE 584
Cdd:pfam05483  417 DEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELE---KEKLKNIELTAH 493

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  585 AREASLRERDTARQQLETV--EKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQE----KAELSQKIGELHACIEASHQ 658
Cdd:pfam05483  494 CDKLLLENKELTQEASDMTleLKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDElesvREEFIQKGDEVKCKLDKSEE 573

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  659 EQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKitKGSLEEEKRRAADALKEQQCRaTEMEAESR 738
Cdd:pfam05483  574 NARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALK--KKGSAENKQLNAYEIKVNKLE-LELASAKQ 650

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  739 SLMEQREREQKELEQEKAGRKGLearIQQLEEAHQAETEALR----------HELAEATASQHRAESECERLIREVESRQ 808
Cdd:pfam05483  651 KFEEIIDNYQKEIEDKKISEEKL---LEEVEKAKAIADEAVKlqkeidkrcqHKIAEMVALMEKHKHQYDKIIEERDSEL 727

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2214681115  809 KRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQL 864
Cdd:pfam05483  728 GLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAIL 783
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 272-908 1.01e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 57.75  E-value: 1.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  272 EPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREfanhlqqlqgAFNDLIEEHSKASQ 351
Cdd:TIGR00606  246 ELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDE----------QLNDLYHNHQRTVR 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  352 EWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQ--LDTLKQEAAKLATDNTQ 429
Cdd:TIGR00606  316 EKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRleLDGFERGPFSERQIKNF 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  430 LQTRVETLEcERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQ 509
Cdd:TIGR00606  396 HTLVIERQE-DEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRIL 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  510 QRDQEL-ASLKEQAKKEQAQMLQTMQEQEQAaqgLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQdhaqqlaivaeaREA 588
Cdd:TIGR00606  475 ELDQELrKAERELSKAEKNSLTETLKKEVKS---LQNEKADLDRKLRKLDQEMEQLNHHTTTRTQ------------MEM 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  589 SLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDnaqtSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVT 668
Cdd:TIGR00606  540 LTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLED----WLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELE 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  669 ELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLK----ITKGSLEEEKRRAADALKEQQC-----RATEMEAESRS 739
Cdd:TIGR00606  616 SKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKqramLAGATAVYSQFITQLTDENQSCcpvcqRVFQTEAELQE 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  740 LMEQRER-------EQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFE 812
Cdd:TIGR00606  696 FISDLQSklrlapdKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLG 775

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  813 ARQQEEarygamfQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSAL 892
Cdd:TIGR00606  776 TIMPEE-------ESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELN 848

                          650
                   ....*....|....*.
gi 2214681115  893 QEKMAATNKEVACLKT 908
Cdd:TIGR00606  849 RKLIQDQQEQIQHLKS 864
mukB PRK04863
chromosome partition protein MukB;
328-674 1.20e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 57.27  E-value: 1.20e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  328 FANHLQQLQGAFNDL---IEEHSKASQEWAEKQARLENELSTALQDKKCLEekneilqgklSQLEDQATRLqespapekg 404
Cdd:PRK04863   346 QQEKIERYQADLEELeerLEEQNEVVEEADEQQEENEARAEAAEEEVDELK----------SQLADYQQAL--------- 406

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  405 evlgDALQLDTLKQEAAKLATDNTQLQTRVETLECErgkqeaQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELE 484
Cdd:PRK04863   407 ----DVQQTRAIQYQQAVQALERAKQLCGLPDLTAD------NAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFE 476

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  485 QASQAQ---GAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQL 561
Cdd:PRK04863   477 QAYQLVrkiAGEVSRSEAWDVARELLRRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDEL 556

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  562 EEAAKEQEATRQDHAQQLAIVAEAREaslrerdTARQQLETVeKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAE 641
Cdd:PRK04863   557 EQLQEELEARLESLSESVSEARERRM-------ALRQQLEQL-QARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQD 628

                          330       340       350
                   ....*....|....*....|....*....|...
gi 2214681115  642 LSQKIGELHACIEASHQEQRQVQARVTELEAQL 674
Cdd:PRK04863   629 VTEYMQQLLERERELTVERDELAARKQALDEEI 661
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 433-775 1.32e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 57.27  E-value: 1.32e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  433 RVETLECERGKQEAQLLAERSRFEDEKQQLA-------SLIADLQSSVSNLS--------QAK--------EELEQASQA 489
Cdd:COG3096    286 RALELRRELFGARRQLAEEQYRLVEMARELEelsaresDLEQDYQAASDHLNlvqtalrqQEKieryqedlEELTERLEE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  490 QGAQLTAQLTSMTGLNATLQQRDQELASLKEQ-AKKEQA-QMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEE---- 563
Cdd:COG3096    366 QEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQlADYQQAlDVQQTRAIQYQQAVQALEKARALCGLPDLTPENAEDylaa 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  564 -AAKEQEATRQ--DHAQQLAIVAEAReaslRERDTARQQLETV--EKEKDAKLESLQQQLQAANDARDNAQTsVTQAQQE 638
Cdd:COG3096    446 fRAKEQQATEEvlELEQKLSVADAAR----RQFEKAYELVCKIagEVERSQAWQTARELLRRYRSQQALAQR-LQQLRAQ 520

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  639 KAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRR 718
Cdd:COG3096    521 LAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAAR 600

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  719 A------ADALKEQQCRATEMEAESRSLME------QREREQKELEQEKAGRKG-LEARIQQLEEAHQAE 775
Cdd:COG3096    601 ApawlaaQDALERLREQSGEALADSQEVTAamqqllEREREATVERDELAARKQaLESQIERLSQPGGAE 670
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 376-593 1.79e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.54  E-value: 1.79e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  376 EKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRF 455
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  456 EDEKQQLASLIADLQS-----------SVSNLSQAK------EELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASL 518
Cdd:COG4942    100 EAQKEELAELLRALYRlgrqpplalllSPEDFLDAVrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2214681115  519 KEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRER 593
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGK 254
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 371-913 1.87e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 56.52  E-value: 1.87e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  371 KKCLEEKNEILQGKLSQLEDQATRLQESPAPEKgEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECE---------- 440
Cdd:TIGR00618  207 TLCTPCMPDTYHERKQVLEKELKHLREALQQTQ-QSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQeavleetqer 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  441 --RGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASL 518
Cdd:TIGR00618  286 inRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVAT 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  519 KEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQ 598
Cdd:TIGR00618  366 SIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAA 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  599 QLETVEKEKDAKlESLQQQLQAANDARdnaqtsvTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQ 678
Cdd:TIGR00618  446 AITCTAQCEKLE-KIHLQESAQSLKER-------EQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPAR 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  679 QKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEE-KRRAADALKEQQCRATEMEAESR--SLMEQREREQKELEQ-E 754
Cdd:TIGR00618  518 QDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSErKQRASLKEQMQEIQQSFSILTQCdnRSKEDIPNLQNITVRlQ 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  755 KAGRKGLEARIQQLEEAHqAETEALRHELAEATASQHRAESEcERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKG 834
Cdd:TIGR00618  598 DLTEKLSEAEDMLACEQH-ALLRKLQPEQDLQDVRLHLQQCS-QELALKLTALHALQLTLTQERVREHALSIRVLPKELL 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  835 EKTGQEVQEEAVEIHSEGQP----GQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLV 910
Cdd:TIGR00618  676 ASRQLALQKMQSEKEQLTYWkemlAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTV 755


                   ...
gi 2214681115  911 LKA 913
Cdd:TIGR00618  756 LKA 758
mukB PRK04863
chromosome partition protein MukB;
429-820 1.91e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 56.89  E-value: 1.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  429 QLQTRVETLECERGKQEAQLLAERSRFEDEKQQLaSLIADLQSSVSNLS---------QAKEELEQASQAQG--AQLTAQ 497
Cdd:PRK04863   841 QLNRRRVELERALADHESQEQQQRSQLEQAKEGL-SALNRLLPRLNLLAdetladrveEIREQLDEAEEAKRfvQQHGNA 919

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  498 LTSMTGLNATLQQRDQELASLKEQAKKEQaQMLQTMQEQEQAAQGLRQQVEQLSSSLKlkEQQLEEAAKEQEATRQDHAQ 577
Cdd:PRK04863   920 LAQLEPIVSVLQSDPEQFEQLKQDYQQAQ-QTQRDAKQQAFALTEVVQRRAHFSYEDA--AEMLAKNSDLNEKLRQRLEQ 996

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  578 qlaivAEAreaslrERDTARQQLetveKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSqkigeLHACIEAsh 657
Cdd:PRK04863   997 -----AEQ------ERTRAREQL----RQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLG-----VPADSGA-- 1054

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  658 qeQRQVQARVTELEAQLKAEQQKTTEREKVVQ----EKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEM 733
Cdd:PRK04863  1055 --EERARARRDELHARLSANRSRRNQLEKQLTfceaEMDNLTKKLRKLERDYHEMREQVVNAKAGWCAVLRLVKDNGVER 1132

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  734 EAESR-----SLMEQREREQKELEQEKAGRKGLEARIQQL---EEAHQAET-------------EALRHELAEAT---AS 789
Cdd:PRK04863  1133 RLHRRelaylSADELRSMSDKALGALRLAVADNEHLRDVLrlsEDPKRPERkvqfyiavyqhlrERIRQDIIRTDdpvEA 1212

                          410       420       430
                   ....*....|....*....|....*....|.
gi 2214681115  790 QHRAESECERLIREVESRQKRFEARQQEEAR 820
Cdd:PRK04863  1213 IEQMEIELSRLTEELTSREQKLAISSESVAN 1243
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1518-1693 1.96e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.48  E-value: 1.96e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1518 ERQRFQEER-QKLTAQVEQLEVFQ-----REQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNE 1591
Cdd:COG1196    206 ERQAEKAERyRELKEELKELEAELlllklRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1592 LQAQLSQKEQAAEhyklQMEKAKTHYDAKKQQNQKLQEQLQ-DLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCR 1670
Cdd:COG1196    286 AQAEEYELLAELA----RLEQDIARLEERRRELEERLEELEeELAELEEELEELEEELEELEEELEEAEEELEEAEAELA 361

                          170       180
                   ....*....|....*....|...
gi 2214681115 1671 HLTAQVRSLEAQVAHADQQLRDL 1693
Cdd:COG1196    362 EAEEALLEAEAELAEAEEELEEL 384
mukB PRK04863
chromosome partition protein MukB;
1404-1695 1.96e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 56.50  E-value: 1.96e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1404 ELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLaeeNRGLGERANLGRQFLEVELDQARE---------KYVQ 1474
Cdd:PRK04863   838 ELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSAL---NRLLPRLNLLADETLADRVEEIREqldeaeeakRFVQ 914

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1475 ELAAVRTDAETHLAEMRQEAQstsrELEVMTAKYEGAkvkvleerqrfQEERQKLTAQVEQL-EVFQREQTKQVEELSKK 1553
Cdd:PRK04863   915 QHGNALAQLEPIVSVLQSDPE----QFEQLKQDYQQA-----------QQTQRDAKQQAFALtEVVQRRAHFSYEDAAEM 979

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1554 LTEHDQASKVQQQKLKAFQAQRgesqqevQRLQTQLNELQAQLSQKEQAaehyklqMEKAKTHYDAKKQQNQKLQEQLQD 1633
Cdd:PRK04863   980 LAKNSDLNEKLRQRLEQAEQER-------TRAREQLRQAQAQLAQYNQV-------LASLKSSYDAKRQMLQELKQELQD 1045

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2214681115 1634 LEELQKENKELRSEAERlgRELQQAglkTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGK 1695
Cdd:PRK04863  1046 LGVPADSGAEERARARR--DELHAR---LSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLER 1102
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1387-1613 2.19e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.54  E-value: 2.19e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1387 AAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELD 1466
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA-ELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1467 QAREKYVQELAAVRTDAETHLAEMrQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKltaQVEQLEVFQREQTKQ 1546
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRAL-YRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE---QAEELRADLAELAAL 165

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2214681115 1547 VEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKA 1613
Cdd:COG4942    166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 275-752 2.39e-07

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 56.34  E-value: 2.39e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  275 ELEELRGKNESltvRLHETLKQCQNLKTEKSQMDRKI----SQLSEENG---DLSFKVREFANHLQQLQGAFNDLIEEHS 347
Cdd:pfam01576   72 ELEEILHELES---RLEEEEERSQQLQNEKKKMQQHIqdleEQLDEEEAarqKLQLEKVTTEAKIKKLEEDILLLEDQNS 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  348 KASQEWAEKQARLeNELSTALQDKkclEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDN 427
Cdd:pfam01576  149 KLSKERKLLEERI-SEFTSNLAEE---EEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQI 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  428 TQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGA-------------QL 494
Cdd:pfam01576  225 AELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKaekqrrdlgeeleAL 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  495 TAQLTSMTGLNATLQ----QRDQELASLK----EQAKKEQAQMLQTMQEQEQAAQGLRQQVEQlsssLKLKEQQLEEAAK 566
Cdd:pfam01576  305 KTELEDTLDTTAAQQelrsKREQEVTELKkaleEETRSHEAQLQEMRQKHTQALEELTEQLEQ----AKRNKANLEKAKQ 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  567 EQEATRQDHAQQLAIVAEAREASLRERDTARQQL----------ETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQ 636
Cdd:pfam01576  381 ALESENAELQAELRTLQQAKQDSEHKRKKLEGQLqelqarlsesERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLS 460

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  637 QEKAELSQKIGELHACIEASHQEQRQVQARVTELEA-------QLKAEQQKTTEREKVVQE-KAQLQEQLRALEESLKIT 708
Cdd:pfam01576  461 KDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDernslqeQLEEEEEAKRNVERQLSTlQAQLSDMKKKLEEDAGTL 540

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 2214681115  709 KGsLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELE 752
Cdd:pfam01576  541 EA-LEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELD 583
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 343-1090 2.56e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.13  E-value: 2.56e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  343 IEEHSKASQEWAEKQARLENELSTALQDKKCL-EEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAA 421
Cdd:pfam02463  158 IEEEAAGSRLKRKKKEALKKLIEETENLAELIiDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEE 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  422 KLATDNTQLQTRVETLECERGKQEAQllAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQasqaQGAQLTAQLTSM 501
Cdd:pfam02463  238 RIDLLQELLRDEQEEIESSKQEIEKE--EEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELK----SELLKLERRKVD 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  502 TGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEaakEQEATRQDHAQQLAI 581
Cdd:pfam02463  312 DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEE---ELLAKKKLESERLSS 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  582 VAEAREASLRERDTARQQLETvEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQR 661
Cdd:pfam02463  389 AAKLKEEELELKSEEEKEAQL-LLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELEL 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  662 QvQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLM 741
Cdd:pfam02463  468 K-KSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAIS 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  742 EQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEAtasQHRAESECERLIREVESRQKRFEARQQEEARY 821
Cdd:pfam02463  547 TAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPL---KSIAVLEIDPILNLAQLDKATLEADEDDKRAK 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  822 GAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNK 901
Cdd:pfam02463  624 VVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKK 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  902 EVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGRPFS-STHAAVKAMEREAEQMGGELERLRAALIKSQG 980
Cdd:pfam02463  704 KEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEeEEKSRLKKEEKEEEKSELSLKEKELAEEREKT 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  981 QQQEERGQQEREVARLTQERGQAQADLaQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQE 1060
Cdd:pfam02463  784 EKLKVEEEKEEKLKAQEEELRALEEEL-KEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEE 862

                          730       740       750
                   ....*....|....*....|....*....|
gi 2214681115 1061 AAQRTELKELQQTLEQLKIQLVKKEKEHPA 1090
Cdd:pfam02463  863 ITKEELLQELLLKEEELEEQKLKDELESKE 892
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 491-722 3.54e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 3.54e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  491 GAQLTAQLTSMTGLNATLQQRDQELASLK---EQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKE 567
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEkelAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  568 QEATRQDHAQQLAIVAEAREASLRERDTARQQLeTVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIG 647
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALYRLGRQPPLAL-LLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2214681115  648 ELHACIEASHQEQRQVQARvteLEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADA 722
Cdd:COG4942    171 AERAELEALLAELEEERAA---LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
620-1169 4.31e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.43  E-value: 4.31e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  620 AANDARDNAQTSVTQAQQEKAELSQKigELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLR 699
Cdd:PRK02224   177 GVERVLSDQRGSLDQLKAQIEEKEEK--DLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  700 ALEES---LKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEE------ 770
Cdd:PRK02224   255 TLEAEiedLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDrleecr 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  771 ----AHQAETEALRH---------------------ELAEATASQHRAESECERLIREVESRQKRFE---ARQQEEARYG 822
Cdd:PRK02224   335 vaaqAHNEEAESLREdaddleeraeelreeaaelesELEEAREAVEDRREEIEELEEEIEELRERFGdapVDLGNAEDFL 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  823 AMFQEQLMALKGE--------KTGQEVQEEAVEIHSEGQ-PGQQQSQLAQLHASlakaiqQVQEKEVRAQKLVDDLSALQ 893
Cdd:PRK02224   415 EELREERDELREReaeleatlRTARERVEEAEALLEAGKcPECGQPVEGSPHVE------TIEEDRERVEELEAELEDLE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  894 EKMAATNKEVACLKTLVlkageqqetaslELLKEPPRAANRASD--QLGEQQgrpfsstHAAVKAMEREAEQMGGELERL 971
Cdd:PRK02224   489 EEVEEVEERLERAEDLV------------EAEDRIERLEERREDleELIAER-------RETIEEKRERAEELRERAAEL 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  972 RAAliksqgqqqeergqqerevARLTQERGQAQADLAQEKAAK-AELEMRLQnTLNEQRVEFAALQEALAhALTEKEGTD 1050
Cdd:PRK02224   550 EAE-------------------AEEKREAAAEAEEEAEEAREEvAELNSKLA-ELKERIESLERIRTLLA-AIADAEDEI 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1051 QELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAGKTDAPGPELQALRAEISKLEQ 1130
Cdd:PRK02224   609 ERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVEN 688

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 2214681115 1131 QCQQQQqqveglthSLKSERACRAEQDKALETLQGQLEE 1169
Cdd:PRK02224   689 ELEELE--------ELRERREALENRVEALEALYDEAEE 719
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
584-1314 4.53e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.46  E-value: 4.53e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  584 EAREASLRE------RDTARQQLETVEKEKDAKLESLQQQLQAAndarDNAQTSVTQAQQEKAELSQKIGELHACIEASH 657
Cdd:PRK03918   145 ESREKVVRQilglddYENAYKNLGEVIKEIKRRIERLEKFIKRT----ENIEELIKEKEKELEEVLREINEISSELPELR 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  658 QEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLE--EEKRRAADALKEQQCRATEMEA 735
Cdd:PRK03918   221 EELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEelEEKVKELKELKEKAEEYIKLSE 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  736 ESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAhQAETEALRHElaeatasqhraESECERLIREVESRQKRFEARQ 815
Cdd:PRK03918   301 FYEEYLDELREIEKRLSRLEEEINGIEERIKELEEK-EERLEELKKK-----------LKELEKRLEELEERHELYEEAK 368

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  816 QEearygamfQEQLMALKGEKTGQEVQeeaveihsegqpgqqqsqlaqlhaslaKAIQQVQEKEVRAQKLVDDLSALQEK 895
Cdd:PRK03918   369 AK--------KEELERLKKRLTGLTPE---------------------------KLEKELEELEKAKEEIEEEISKITAR 413

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  896 MAATNKEVACLKTLVLKageqqetasLELLKEPPRAANRASDQlgEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAAL 975
Cdd:PRK03918   414 IGELKKEIKELKKAIEE---------LKKAKGKCPVCGRELTE--EHRKELLEEYTAELKRIEKELKEIEEKERKLRKEL 482

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  976 IKSQGQQQEERgqqerevaRLTQERGQAQadlaQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAK 1055
Cdd:PRK03918   483 RELEKVLKKES--------ELIKLKELAE----QLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEK 550

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1056 LRGQEaaqrTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDasgpgtqsetagktdapgpelqALRAEISKLEQQCQQQ 1135
Cdd:PRK03918   551 LEELK----KKLAELEKKLDELEEELAELLKELEELGFESVE----------------------ELEERLKELEPFYNEY 604

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1136 QqqveglthSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAqdhskAEEEWKaqvaRGQQE 1215
Cdd:PRK03918   605 L--------ELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKY-----SEEEYE----ELREE 667

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1216 AERKSSLISSLEEEVSILNRQVLEKEGESKELKRlvvaESEKSQKLEERLRLLQvetasnsaRAAERSSALREEVQSLRE 1295
Cdd:PRK03918   668 YLELSRELAGLRAELEELEKRREEIKKTLEKLKE----ELEEREKAKKELEKLE--------KALERVEELREKVKKYKA 735

                          730
                   ....*....|....*....
gi 2214681115 1296 EVEKQrvvSENSRQELASQ 1314
Cdd:PRK03918   736 LLKER---ALSKVGEIASE 751
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1243-1684 4.92e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.16  E-value: 4.92e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1243 ESKELKRLVVAESEKSQKLEERLRLLQvETASNSARAAERSSALREEVQSLREEVEKQRVVSENS--RQELASQAERAEE 1320
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELE-ELEEELEELEAELEELREELEKLEKLLQLLPLYQELEalEAELAELPERLEE 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1321 LGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHlcqQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQR 1400
Cdd:COG4717    151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE---EELQDLAEELEELQQRLAELEEELEEAQEELEELEE 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1401 ELGELGSLRQKIVEQERAaQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVR 1480
Cdd:COG4717    228 ELEQLENELEAAALEERL-KEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1481 TDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEER-QRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQ 1559
Cdd:COG4717    307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRiEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEE 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1560 AskvqqqklkafqAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAkthydakkQQNQKLQEQLQDLEELQK 1639
Cdd:COG4717    387 L------------RAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEE--------ELEEELEELEEELEELEE 446

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 2214681115 1640 ENKELRSEAERLGRELQQAGLKTK--EAEQTCRHLTAQVRSLEAQVA 1684
Cdd:COG4717    447 ELEELREELAELEAELEQLEEDGElaELLQELEELKAELRELAEEWA 493
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1155-1655 5.09e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.77  E-value: 5.09e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1155 EQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAErksslISSLEEEVSILN 1234
Cdd:COG4717     78 EELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAE-----LAELPERLEELE 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1235 RQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQ 1314
Cdd:COG4717    153 ERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1315 AERAEELGQELKAWQEKFFQKEQA-LSALQLEHTSTQALVSELLPAkhlcqqlqaeqaaaekrfreeleqskqAAGGLQA 1393
Cdd:COG4717    233 ENELEAAALEERLKEARLLLLIAAaLLALLGLGGSLLSLILTIAGV---------------------------LFLVLGL 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1394 ELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYV 1473
Cdd:COG4717    286 LALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQL 365

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1474 QELaavrtdaETHLAEMRQEAQSTSRElevmtakyegakvkVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKK 1553
Cdd:COG4717    366 EEL-------EQEIAALLAEAGVEDEE--------------ELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEA 424

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1554 LTEHDQASKVQQ--QKLKAFQAQRGESQQEVQRLQTQLNELQAQ--LSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQE 1629
Cdd:COG4717    425 LDEEELEEELEEleEELEELEEELEELREELAELEAELEQLEEDgeLAELLQELEELKAELRELAEEWAALKLALELLEE 504

                          490       500
                   ....*....|....*....|....*.
gi 2214681115 1630 QLQDLEELQKEnkELRSEAERLGREL 1655
Cdd:COG4717    505 AREEYREERLP--PVLERASEYFSRL 528
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
993-1537 5.32e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.05  E-value: 5.32e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  993 VARLTQERGQAQADLAQEKAAKAELEmrLQNTLNEQRVEFAALQEALAHALTEKE---GTDQELAKLRGQEAAQRTELKE 1069
Cdd:PRK02224   178 VERVLSDQRGSLDQLKAQIEEKEEKD--LHERLNGLESELAELDEEIERYEEQREqarETRDEADEVLEEHEERREELET 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1070 LQQTLEQL--KIQLVKKEKEHPAGGASGEDASGPGTQSE---TAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGL-- 1142
Cdd:PRK02224   256 LEAEIEDLreTIAETEREREELAEEVRDLRERLEELEEErddLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECrv 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1143 ---THSLKSERAcrAEQDKALETLQGQLEEKARELGhnqAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERK 1219
Cdd:PRK02224   336 aaqAHNEEAESL--REDADDLEERAEELREEAAELE---SELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNA 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1220 SSLISSLEEEVSILNRQVLEKEGESKELKRLVvaesEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEK 1299
Cdd:PRK02224   411 EDFLEELREERDELREREAELEATLRTARERV----EEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELED 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1300 QRVvsenSRQELASQAERAEELgQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHlcqqlqaeqaAAEKRFRE 1379
Cdd:PRK02224   487 LEE----EVEEVEERLERAEDL-VEAEDRIERLEERREDLEELIAERRETIEEKRERAEELR----------ERAAELEA 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1380 ELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLR---AEKASYAEQLSMLKKAHGLLAEENR----GLGE 1452
Cdd:PRK02224   552 EAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRtllAAIADAEDEIERLREKREALAELNDerreRLAE 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1453 RANLGRQfLEVELDQARekyVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKvLEERQRFQEERQKLTAQ 1532
Cdd:PRK02224   632 KRERKRE-LEAEFDEAR---IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENE-LEELEELRERREALENR 706


                   ....*
gi 2214681115 1533 VEQLE 1537
Cdd:PRK02224   707 VEALE 711
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
407-640 5.68e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 54.64  E-value: 5.68e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  407 LGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSR-----FEDEKQQLASLIADLQSSvsnLSQAKE 481
Cdd:COG3206    157 LAEAYLEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKnglvdLSEEAKLLLQQLSELESQ---LAEARA 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  482 ELEQAsQAQGAQLTAQLTSMTGLNATLQQrDQELASLKEQ---AKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKlke 558
Cdd:COG3206    234 ELAEA-EARLAALRAQLGSGPDALPELLQ-SPVIQQLRAQlaeLEAELAELSARYTPNHPDVIALRAQIAALRAQLQ--- 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  559 QQLEEAAKEQEATRQdhaqqlaiVAEAREASLRER-DTARQQLETVeKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQ 637
Cdd:COG3206    309 QEAQRILASLEAELE--------ALQAREASLQAQlAQLEARLAEL-PELEAELRRLEREVEVARELYESLLQRLEEARL 379


                   ...
gi 2214681115  638 EKA 640
Cdd:COG3206    380 AEA 382
46 PHA02562
endonuclease subunit; Provisional
 305-567 6.88e-07

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 54.25  E-value: 6.88e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  305 SQMDR----KISQLSEENGDLSFKVrefaNHLQQLQGAFNDLIEEHSKAS-QEWAEKQARLENELSTALQDKKCLEEKNE 379
Cdd:PHA02562   166 SEMDKlnkdKIRELNQQIQTLDMKI----DHIQQQIKTYNKNIEEQRKKNgENIARKQNKYDELVEEAKTIKAEIEELTD 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  380 ILQGKLSQLEDQATRLQEspapekgevlgdalqldtLKQEAAKLATDNTQLQTRVETLE----CERGKQeaQLLAERSRF 455
Cdd:PHA02562   242 ELLNLVMDIEDPSAALNK------------------LNTAAAKIKSKIEQFQKVIKMYEkggvCPTCTQ--QISEGPDRI 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  456 EDEKQQlaslIADLQSSVSNLSQAKEELEQasqaQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMlqtmqE 535
Cdd:PHA02562   302 TKIKDK----LKELQHSLEKLDTAIDELEE----IMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAI-----E 368

                          250       260       270
                   ....*....|....*....|....*....|...
gi 2214681115  536 QEQAAQGLR-QQVEQLSSSLKLKEQQLEEAAKE 567
Cdd:PHA02562   369 ELQAEFVDNaEELAKLQDELDKIVKTKSELVKE 401
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 218-1087 7.42e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.59  E-value: 7.42e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  218 KKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASSQEPSELEELRGKNESLTVRLHETLKQC 297
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  298 QNLKTEKSQ--------MDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQ 369
Cdd:pfam02463  260 IEKEEEKLAqvlkenkeEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  370 DKKCLEEKnEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQtrvetlecERGKQEAQLL 449
Cdd:pfam02463  340 LEKELKEL-EIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELK--------SEEEKEAQLL 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  450 AERSrfedekQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQM 529
Cdd:pfam02463  411 LELA------RQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  530 LQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDA 609
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQ 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  610 KLeslqqqLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQ 689
Cdd:pfam02463  565 KL------VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  690 EKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLE 769
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLE 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  770 EahqAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEaveih 849
Cdd:pfam02463  719 A---EELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEE----- 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  850 segqpgQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEpp 929
Cdd:pfam02463  791 ------EKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEE-- 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  930 raaNRASDQLGEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQ 1009
Cdd:pfam02463  863 ---ITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEE 939

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2214681115 1010 EKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKE 1087
Cdd:pfam02463  940 LLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
533-775 7.52e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 54.25  E-value: 7.52e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  533 MQEQEQAAQGLRQQVEQLssslklkEQQLEEAAKEQEATRQDHAqqlaIVAeareaslrerdtarqqLETVEKEKDAKLE 612
Cdd:COG3206    170 REEARKALEFLEEQLPEL-------RKELEEAEAALEEFRQKNG----LVD----------------LSEEAKLLLQQLS 222

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  613 SLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELhacieASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQeka 692
Cdd:COG3206    223 ELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL-----LQSPVIQQLRAQLAELEAELAELSARYTPNHPDVI--- 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  693 QLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLME---QREREQKELEQE-KAGRKGLEARIQQL 768
Cdd:COG3206    295 ALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAelpELEAELRRLEREvEVARELYESLLQRL 374


                   ....*..
gi 2214681115  769 EEAHQAE 775
Cdd:COG3206    375 EEARLAE 381
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
253-649 8.79e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.00  E-value: 8.79e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  253 QQRIDHLALLNEKQAASSQEPSELEELRGKNESLtVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHL 332
Cdd:COG4717     91 AELQEELEELEEELEELEAELEELREELEKLEKL-LQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELE 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  333 QQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQ-ESPAPEKGEVLGDAL 411
Cdd:COG4717    170 AELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLEnELEAAALEERLKEAR 249

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  412 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQG 491
Cdd:COG4717    250 LLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALG 329

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  492 AQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLrQQVEQLSSSLKLKEQQLEEAAKEQEAT 571
Cdd:COG4717    330 LPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGV-EDEEELRAALEQAEEYQELKEELEELE 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  572 RQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTS--VTQAQQEKAELSQKIGEL 649
Cdd:COG4717    409 EQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDgeLAELLQELEELKAELREL 488
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 444-906 9.97e-07

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 54.42  E-value: 9.97e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  444 QEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQltsmtglnATLQQRDQELASLKEQAK 523
Cdd:PRK10246   217 QVQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTRLDELQQEASRRQQALQQAL--------AAEEKAQPQLAALSLAQP 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  524 KEQAQML-QTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEE-------AAKEQEATRQDHAQQLAIVAEAR--------- 586
Cdd:PRK10246   289 ARQLRPHwERIQEQSAALAHTRQQIEEVNTRLQSTMALRARirhhaakQSAELQAQQQSLNTWLAEHDRFRqwnnelagw 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  587 EASLRERDTARQQLETVEkekdAKLESLQQQLQAAND------ARDNAQTSVTQAQQEKaeLSQKIGELHACIEASHQEQ 660
Cdd:PRK10246   369 RAQFSQQTSDREQLRQWQ----QQLTHAEQKLNALPAitltltADEVAAALAQHAEQRP--LRQRLVALHGQIVPQQKRL 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  661 RQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKgSLEEEKRRAADALKEQQCRATEMEAESrsl 740
Cdd:PRK10246   443 AQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEARIK-DLEAQRAQLQAGQPCPLCGSTSHPAVE--- 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  741 meqrEREQKELEQEKAGRKGLEARIQQLEEahqaETEALRHELAEATASQHRAESECERLIREvesRQKRFEARQQEEAR 820
Cdd:PRK10246   519 ----AYQALEPGVNQSRLDALEKEVKKLGE----EGAALRGQLDALTKQLQRDESEAQSLRQE---EQALTQQWQAVCAS 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  821 YGAMFQEQlMALKGEKTGQEVQEEAVEihsegQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATN 900
Cdd:PRK10246   588 LNITLQPQ-DDIQPWLDAQEEHERQLR-----LLSQRHELQGQIAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQED 661


                   ....*.
gi 2214681115  901 KEVACL 906
Cdd:PRK10246   662 EEASWL 667
PRK11281 PRK11281
mechanosensitive channel MscK;
412-712 1.03e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 54.15  E-value: 1.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  412 QLDTLKQEAAKLATDNTQLQTRVETLEC--ERGKQEAQLLAERSRFEDEKQQLASLIADLQS-SVSNLSQAKEELEQASQ 488
Cdd:PRK11281    44 QLDALNKQKLLEAEDKLVQQDLEQTLALldKIDRQKEETEQLKQQLAQAPAKLRQAQAELEAlKDDNDEETRETLSTLSL 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  489 AQ-GAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQM---LQTMQEQEQAAQGLRQQVEQLSSSLKLK---EQQL 561
Cdd:PRK11281   124 RQlESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALyanSQRLQQIRNLLKGGKVGGKALRPSQRVLlqaEQAL 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  562 EEAAKEQEATRQDHAQQLAIVAEAReaslRERDTARQQLetvekekdakLESLQQQLQAANDARDNAQTSVTQAQQEKAE 641
Cdd:PRK11281   204 LNAQNDLQRKSLEGNTQLQDLLQKQ----RDYLTARIQR----------LEHQLQLLQEAINSKRLTLSEKTVQEAQSQD 269

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2214681115  642 LSQKIGE---LHACIEASHQ-EQRQVQArvTELEAQLKAEQQKTtereKVVQEKAQlQEQlRALEESLKITKGSL 712
Cdd:PRK11281   270 EAARIQAnplVAQELEINLQlSQRLLKA--TEKLNTLTQQNLRV----KNWLDRLT-QSE-RNIKEQISVLKGSL 336
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 294-882 1.13e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.28  E-value: 1.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  294 LKQCQNLKTEKSQMDRKISQLSEENGDLsfkvrefaNHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQD--- 370
Cdd:TIGR00606  500 KKEVKSLQNEKADLDRKLRKLDQEMEQL--------NHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYfpn 571

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  371 KKCLEEKNEILQGKLSQLEDQATRLQESPAPekgevlGDALQLDTLKQEAAKLATDNTQLQTRVETLECErgKQEAQLLA 450
Cdd:TIGR00606  572 KKQLEDWLHSKSKEINQTRDRLAKLNKELAS------LEQNKNHINNELESKEEQLSSYEDKLFDVCGSQ--DEESDLER 643

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  451 ERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQA---------SQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQ 521
Cdd:TIGR00606  644 LKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCcpvcqrvfqTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEK 723

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  522 AKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAtrqdhaQQLAIVAEAREASLRERD-TARQQL 600
Cdd:TIGR00606  724 RRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQET------LLGTIMPEEESAKVCLTDvTIMERF 797

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  601 ETVEKEKDAKLESLQQQLQAANDARdnAQTSVTQAQQEKAE----LSQKIGELHACIEASHQEQRQVQARVTELEAQLKA 676
Cdd:TIGR00606  798 QMELKDVERKIAQQAAKLQGSDLDR--TVQQVNQEKQEKQHeldtVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQ 875

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  677 EQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKA 756
Cdd:TIGR00606  876 IGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHG 955

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  757 GRKGLEARIQQLEEAHQAETEalrHELAEATASQHRAESECERLIREVESRQKRFEARQQEEarygAMFQEQLMALKGEK 836
Cdd:TIGR00606  956 YMKDIENKIQDGKDDYLKQKE---TELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQE----RWLQDNLTLRKREN 1028

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 2214681115  837 TGQEVQEEAVEihSEGQPGQQQ-SQLAQLHASLAKAIQQVQEKEVRA 882
Cdd:TIGR00606 1029 ELKEVEEELKQ--HLKEMGQMQvLQMKQEHQKLEENIDLIKRNHVLA 1073
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1452-1658 1.20e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.87  E-value: 1.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1452 ERANLGRQFLEVELDQAREKYVQ-ELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLT 1530
Cdd:COG3206    171 EEARKALEFLEEQLPELRKELEEaEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLG 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1531 AQVEQLEVFQreQTKQVEELSKKLTEhdqaskvQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAehyklqM 1610
Cdd:COG3206    251 SGPDALPELL--QSPVIQQLRAQLAE-------LEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRI------L 315

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2214681115 1611 EKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQA 1658
Cdd:COG3206    316 ASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVA 363
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1281-1683 1.24e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.89  E-value: 1.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1281 ERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELkawqekffqkEQALSALQLEHTSTQALvsellpak 1360
Cdd:PRK02224   251 EELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEER----------DDLLAEAGLDDADAEAV-------- 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1361 hlcQQLQAEQAAAEKRFREELEQSKQAAGGLQAElmrAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAH 1440
Cdd:PRK02224   313 ---EARREELEDRDEELRDRLEECRVAAQAHNEE---AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEI 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1441 GLLAEENRGLGERANlgrqFLEVELDQArEKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAK-------- 1512
Cdd:PRK02224   387 EELEEEIEELRERFG----DAPVDLGNA-EDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqpv 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1513 -----VKVLEERQrfqEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQ-----KLKAFQAQRGESQQE- 1581
Cdd:PRK02224   462 egsphVETIEEDR---ERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERredleELIAERRETIEEKREr 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1582 VQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTH---YDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQA 1658
Cdd:PRK02224   539 AEELRERAAELEAEAEEKREAAAEAEEEAEEAREEvaeLNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREAL 618

                          410       420
                   ....*....|....*....|....*
gi 2214681115 1659 GLKTKEAEQTCRHLTAQVRSLEAQV 1683
Cdd:PRK02224   619 AELNDERRERLAEKRERKRELEAEF 643
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1117-1651 1.43e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.51  E-value: 1.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1117 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEqdkaLETLQGQLEEKarelghnQAASASAQRELQALRAKAQ 1196
Cdd:PRK02224   214 ELAELDEEIERYEEQREQARETRDEADEVLEEHEERREE----LETLEAEIEDL-------RETIAETEREREELAEEVR 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1197 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQvlekegeskelkrlvvaESEKSQKLEERlRLLQVETASNS 1276
Cdd:PRK02224   283 DLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDR-----------------DEELRDRLEEC-RVAAQAHNEEA 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1277 ARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1356
Cdd:PRK02224   345 ESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDEL 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1357 LPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGElgsLRQKIVEQERAAQQLRAEKASYAEQLSML 1436
Cdd:PRK02224   425 REREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEE---DRERVEELEAELEDLEEEVEEVEERLERA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1437 KKAHGLLAEENRgLGERanlgRQFLEVELDQAREKyvqelAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVL 1516
Cdd:PRK02224   502 EDLVEAEDRIER-LEER----REDLEELIAERRET-----IEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAR 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1517 EERQRFQEERQKLTAQVEQLEvfqreqtkQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQA-- 1594
Cdd:PRK02224   572 EEVAELNSKLAELKERIESLE--------RIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAef 643

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2214681115 1595 ------QLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQK----LQEQLQDLEELQKENKELRSEAERL 1651
Cdd:PRK02224   644 dearieEAREDKERAEEYLEQVEEKLDELREERDDLQAeigaVENELEELEELRERREALENRVEAL 710
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1211-1659 1.68e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 53.42  E-value: 1.68e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1211 RGQQEAERKSSLISSLEEEVSILNRQVLEKEGE----SKELKRLVVAESEKSQKLE---ERLRLLQvetasNSARAAERS 1283
Cdd:COG3096    275 RHANERRELSERALELRRELFGARRQLAEEQYRlvemARELEELSARESDLEQDYQaasDHLNLVQ-----TALRQQEKI 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1284 SALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLC 1363
Cdd:COG3096    350 ERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKARALC 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1364 qqlqaeqaaaekrfrEELEQSKQAAGGLQAELMRAQRELGE-LGSLRQKIVEQERAAQQlraekasYAEQLSMLKKAHGl 1442
Cdd:COG3096    430 ---------------GLPDLTPENAEDYLAAFRAKEQQATEeVLELEQKLSVADAARRQ-------FEKAYELVCKIAG- 486

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1443 laeenrglgeranlgrqflEVELDQAREKYVQELAAVRTDAetHLAEMRQEAQSTSRELEvmtakyegakvkvleerQRF 1522
Cdd:COG3096    487 -------------------EVERSQAWQTARELLRRYRSQQ--ALAQRLQQLRAQLAELE-----------------QRL 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1523 qEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQA 1602
Cdd:COG3096    529 -RQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAA 607

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2214681115 1603 AEHY-KLQMEKAKTHYDAKKQQNQkLQEQLQDLEELQKENKELRSEAERLG---RELQQAG 1659
Cdd:COG3096    608 QDALeRLREQSGEALADSQEVTAA-MQQLLEREREATVERDELAARKQALEsqiERLSQPG 667
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 206-777 1.73e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 53.43  E-value: 1.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  206 ILQTPQFQMRRLKKQLADERSNRDDLELELSESLKLLTekdaqiamMQQRIDHLALLNEKQAA----SSQEPSELEELRG 281
Cdd:TIGR00618  312 IHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQT--------LHSQEIHIRDAHEVATSireiSCQQHTLTQHIHT 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  282 KNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVRefANHLQQLQGAFNDLIEEHSKASQEWAEKQARLE 361
Cdd:TIGR00618  384 LQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAH--AKKQQELQQRYAELCAAAITCTAQCEKLEKIHL 461

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  362 NELSTALQDKKCLEEKNEILQGKLSQL----EDQATRLQESPAPEKGEVLGDALQLdTLKQEAAKLATDNTQLQTRVETL 437
Cdd:TIGR00618  462 QESAQSLKEREQQLQTKEQIHLQETRKkavvLARLLELQEEPCPLCGSCIHPNPAR-QDIDNPGPLTRRMQRGEQTYAQL 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  438 ECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASqaqgaQLTAQLTSMTGLNATLQQRDQELAS 517
Cdd:TIGR00618  541 ETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQ-----NITVRLQDLTEKLSEAEDMLACEQH 615

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  518 LKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSS-SLKLKEQQLEEAAKeqeATRQDHAQQLAIvaeaREASLRERDTA 596
Cdd:TIGR00618  616 ALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHAlQLTLTQERVREHAL---SIRVLPKELLAS----RQLALQKMQSE 688

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  597 RQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACI-EASHQEQRQVQARVTELEA--- 672
Cdd:TIGR00618  689 KEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLkELMHQARTVLKARTEAHFNnne 768

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  673 QLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELE 752
Cdd:TIGR00618  769 EVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEIT 848

                          570       580
                   ....*....|....*....|....*
gi 2214681115  753 QEKagrKGLEARIQQLEEAHQAETE 777
Cdd:TIGR00618  849 HQL---LKYEECSKQLAQLTQEQAK 870
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 405-1081 2.34e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.87  E-value: 2.34e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  405 EVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAE----------RSRFEDEKQQLASLIADLQSSVS 474
Cdd:pfam01576    6 EMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAEtelcaeaeemRARLAARKQELEEILHELESRLE 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  475 NLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLqTMQEQEQAAQGLRQQVEQLSSSL 554
Cdd:pfam01576   86 EEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDIL-LLEDQNSKLSKERKLLEERISEF 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  555 KLKEQQLEEAAKEQEATRQDHAQQLAIVaearEASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQ 634
Cdd:pfam01576  165 TSNLAEEEEKAKSLSKLKNKHEAMISDL----EERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAK 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  635 AQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQkttEREKVVQEKAQLQEQLRA----LEESLKITKG 710
Cdd:pfam01576  241 KEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERA---ARNKAEKQRRDLGEELEAlkteLEDTLDTTAA 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  711 SLEEEKRRAADALKEQQCRATEMEAESRSLMEQRERE-------QKELEQEKAGRKGLEARIQQLEEAhqaetealRHEL 783
Cdd:pfam01576  318 QQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHtqaleelTEQLEQAKRNKANLEKAKQALESE--------NAEL 389

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  784 AEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGE---KTGQEVQEEAVEIHSEGQPGQQQSQ 860
Cdd:pfam01576  390 QAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSElesVSSLLNEAEGKNIKLSKDVSSLESQ 469

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  861 LAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKM-------AATNKEVACLKTLV--LKAGEQQETASLELLKEPPRA 931
Cdd:pfam01576  470 LQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLeeeeeakRNVERQLSTLQAQLsdMKKKLEEDAGTLEALEEGKKR 549

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  932 ANRASDQLGEQqgrpFSSTHAAVKAMEREAEQMGGELE----------RLRAALIKSQGQQQEERGQQEREVARLTQERG 1001
Cdd:pfam01576  550 LQRELEALTQQ----LEEKAAAYDKLEKTKNRLQQELDdllvdldhqrQLVSNLEKKQKKFDQMLAEEKAISARYAEERD 625

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1002 QAQADlAQEKAAKAELEMRLQNTLNEQRVEF----AALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQL 1077
Cdd:pfam01576  626 RAEAE-AREKETRALSLARALEEALEAKEELertnKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEEL 704


                   ....
gi 2214681115 1078 KIQL 1081
Cdd:pfam01576  705 EDEL 708
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1140-1672 3.31e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.66  E-value: 3.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1140 EGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARgQQEAERK 1219
Cdd:TIGR00618  197 ELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRAR-IEELRAQ 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1220 SSLISSLEEEVSiLNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEK 1299
Cdd:TIGR00618  276 EAVLEETQERIN-RARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1300 QRVVSENSRQEL-ASQAERAEELGQELKAWQEK---FFQKEQALSALQLEHTSTQALVSEL----------LPAKHLCQQ 1365
Cdd:TIGR00618  355 IHIRDAHEVATSiREISCQQHTLTQHIHTLQQQkttLTQKLQSLCKELDILQREQATIDTRtsafrdlqgqLAHAKKQQE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1366 LQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKAS-YAEQLSMLKKAHGLLA 1444
Cdd:TIGR00618  435 LQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLeLQEEPCPLCGSCIHPN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1445 EENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAET-HLAEMRQEAQSTSRELEVMTAKYEGAKV---KVLEERQ 1520
Cdd:TIGR00618  515 PARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERkQRASLKEQMQEIQQSFSILTQCDNRSKEdipNLQNITV 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1521 RFQEERQKLTAQVEQLEVFQREQTKQVEE---LSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLS 1597
Cdd:TIGR00618  595 RLQDLTEKLSEAEDMLACEQHALLRKLQPeqdLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKEL 674

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2214681115 1598 QKEQAAEHYKLQMEKAKTHYDAK--KQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHL 1672
Cdd:TIGR00618  675 LASRQLALQKMQSEKEQLTYWKEmlAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQ 751
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 653-1690 3.62e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.48  E-value: 3.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  653 IEASHQEQRQVQARVTELEAQLKAEQQKTTErekVVQEKAQLQEQLRALEESLKitkgslEEEKRRAADALKEQQCRATE 732
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQ---LCEEKNALQEQLQAETELCA------EAEEMRARLAARKQELEEIL 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  733 MEAESRslMEQREREQKELEQEKagrKGLEARIQQLEEaHQAETEALRHELaeatasqHRAESECERLIREVESRQKRFE 812
Cdd:pfam01576   78 HELESR--LEEEEERSQQLQNEK---KKMQQHIQDLEE-QLDEEEAARQKL-------QLEKVTTEAKIKKLEEDILLLE 144

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  813 ARQQEEARYGAMFQEQLmalkGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSAL 892
Cdd:pfam01576  145 DQNSKLSKERKLLEERI----SEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDL 220

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  893 QEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASdqlgeqqgrpfssthaAVKAMEREAEQMGGELERLR 972
Cdd:pfam01576  221 QEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALK----------------KIRELEAQISELQEDLESER 284

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  973 AALIKSQgqqqeergqqerevarltqergQAQADLAQE-KAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQ 1051
Cdd:pfam01576  285 AARNKAE----------------------KQRRDLGEElEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRS 342

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1052 ELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGpgtqsetagktdapgpELQALRAEISKLEQQ 1131
Cdd:pfam01576  343 HEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQA----------------ELRTLQQAKQDSEHK 406

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1132 CQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQD-HSKAEEEWKAQVA 1210
Cdd:pfam01576  407 RKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDtQELLQEETRQKLN 486

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1211 ---RGQQEAERKSSLISSLEEEVSI---LNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSS 1284
Cdd:pfam01576  487 lstRLRQLEDERNSLQEQLEEEEEAkrnVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAA 566

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1285 A---LREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQ---ELKAWQEKFFQKEQALSALQLEHTSTQALVSELLP 1358
Cdd:pfam01576  567 AydkLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQmlaEEKAISARYAEERDRAEAEAREKETRALSLARALE 646

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1359 AKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQREL-GELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLK 1437
Cdd:pfam01576  647 EALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALeQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALK 726

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1438 KAH--GLLAEENRGLGERANLGRQF--LEVELDQAREKYVQELAAvRTDAETHLAEMRQEAQSTSRelevmtakyegAKV 1513
Cdd:pfam01576  727 AQFerDLQARDEQGEEKRRQLVKQVreLEAELEDERKQRAQAVAA-KKKLELDLKELEAQIDAANK-----------GRE 794

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1514 KVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLN--- 1590
Cdd:pfam01576  795 EAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIAsga 874

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1591 -----------ELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQqag 1659
Cdd:pfam01576  875 sgksalqdekrRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELK--- 951

                         1050      1060      1070
                   ....*....|....*....|....*....|..
gi 2214681115 1660 LKTKEAEQTCR-HLTAQVRSLEAQVAHADQQL 1690
Cdd:pfam01576  952 AKLQEMEGTVKsKFKSSIAALEAKIAQLEEQL 983
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1526-1693 4.32e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 52.08  E-value: 4.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1526 RQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEH 1605
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1606 YKL--QMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTK-EAEQTCRHLTAQVRSLEAQ 1682
Cdd:COG4717    128 LPLyqELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQR 207

                          170
                   ....*....|.
gi 2214681115 1683 VAHADQQLRDL 1693
Cdd:COG4717    208 LAELEEELEEA 218
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
504-898 5.38e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.69  E-value: 5.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  504 LNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHaQQLAIVA 583
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREEL-EKLEKLL 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  584 EAREAsLRERDTARQQLETVE------KEKDAKLESLQQQLQAANDARDNAQTSVTQA-QQEKAELSQKIGELHACIEAS 656
Cdd:COG4717    126 QLLPL-YQELEALEAELAELPerleelEERLEELRELEEELEELEAELAELQEELEELlEQLSLATEEELQDLAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  657 HQEQRQVQARVTELEAQLKAEQQKTTEREKvVQEKAQLQEQLRALEESLKI---------TKGSLEEEKRRAADALKEQQ 727
Cdd:COG4717    205 QQRLAELEEELEEAQEELEELEEELEQLEN-ELEAAALEERLKEARLLLLIaaallallgLGGSLLSLILTIAGVLFLVL 283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  728 CRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAE------------ATASQHRAES 795
Cdd:COG4717    284 GLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLElldrieelqellREAEELEEEL 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  796 ECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKtgQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQV 875
Cdd:COG4717    364 QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEEL--EELEEQLEELLGELEELLEALDEEELEEELEELEEEL 441

                          410       420
                   ....*....|....*....|...
gi 2214681115  876 QEKEVRAQKLVDDLSALQEKMAA 898
Cdd:COG4717    442 EELEEELEELREELAELEAELEQ 464
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1183-1711 6.04e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 51.76  E-value: 6.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1183 SAQRELQALRAKAQDHSKAEEEWKAQVARGQQEaerKSSLISSLEEEVsilNRQVLEKEGESKELKRLVVAESEKSQKLE 1262
Cdd:pfam12128  255 SAELRLSHLHFGYKSDETLIASRQEERQETSAE---LNQLLRTLDDQW---KEKRDELNGELSAADAAVAKDRSELEALE 328

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1263 ERLRLLQVETASNSARAAERSSALREEVQSLREEVE-----KQRVVSENSRQELASQAERAEELgQELKAWQEKffQKEQ 1337
Cdd:pfam12128  329 DQHGAFLDADIETAAADQEQLPSWQSELENLEERLKaltgkHQDVTAKYNRRRSKIKEQNNRDI-AGIKDKLAK--IREA 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1338 ALSALQLEHTSTQALVSELlpakhlcqqlQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQER 1417
Cdd:pfam12128  406 RDRQLAVAEDDLQALESEL----------REQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFDERIER 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1418 AAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGeRANLGRQFLEVELDQAREKYVQE----LAAVRTDA---ETHLAEM 1490
Cdd:pfam12128  476 AREEQEAANAEVERLQSELRQARKRRDQASEALR-QASRRLEERQSALDELELQLFPQagtlLHFLRKEApdwEQSIGKV 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1491 RQEAQ-------------STSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEH 1557
Cdd:pfam12128  555 ISPELlhrtdldpevwdgSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGEL 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1558 DQASKVQQQKLKAFQAQRgesqqevQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAkkQQNQKLQEQLQDLEEL 1637
Cdd:pfam12128  635 EKASREETFARTALKNAR-------LDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEA--QLKQLDKKHQAWLEEQ 705

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2214681115 1638 QKENKELRSEAERLGRELQQAgLKTKEAEQTCRHLTAQVrSLEAQVAHADQQL-RDLGKFQVATDALKSREPQVK 1711
Cdd:pfam12128  706 KEQKREARTEKQAYWQVVEGA-LDAQLALLKAAIAARRS-GAKAELKALETWYkRDLASLGVDPDVIAKLKREIR 778
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 628-845 6.58e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 6.58e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  628 AQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREkvvQEKAQLQEQLRALEESLKI 707
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  708 TKGSLEEEKRRAADALKEQQ--------------CRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAhQ 773
Cdd:COG4942     95 LRAELEAQKEELAELLRALYrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE-R 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2214681115  774 AETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEA 845
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1008-1537 7.40e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.45  E-value: 7.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1008 AQEKAAKAELEMRLQNTLnEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLvkkeke 1087
Cdd:COG4913    260 LAERYAAARERLAELEYL-RAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQI------ 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1088 hpaggasgedasgpgtqsetagkTDAPGPELQALRAEISKLEQQCQQQQQQveglthslkseracRAEQDKALETLQGQL 1167
Cdd:COG4913    333 -----------------------RGNGGDRLEQLEREIERLERELEERERR--------------RARLEALLAALGLPL 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1168 EEKARELGHNQAASASAQRELQALRAKAQDhskAEEEWKAQVARGQQEAERKSSLISSLEEEVS------ILNRQVLEKE 1241
Cdd:COG4913    376 PASAEEFAALRAEAAALLEALEEELEALEE---ALAEAEAALRDLRRELRELEAEIASLERRKSniparlLALRDALAEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1242 -----------GESKELK-------------------RLVVAESEKSQ--------KLEERLRLLQVETASNSARAAE-- 1281
Cdd:COG4913    453 lgldeaelpfvGELIEVRpeeerwrgaiervlggfalTLLVPPEHYAAalrwvnrlHLRGRLVYERVRTGLPDPERPRld 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1282 ----------RSSALREEVQSL----------------------------------------REEVEKQRVVSENSRQEL 1311
Cdd:COG4913    533 pdslagkldfKPHPFRAWLEAElgrrfdyvcvdspeelrrhpraitragqvkgngtrhekddRRRIRSRYVLGFDNRAKL 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1312 ASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALvsellpakhlcqqlqaeqaaaekrfrEELEQSKQAAGGL 1391
Cdd:COG4913    613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRL--------------------------AEYSWDEIDVASA 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1392 QAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEEnrglgeranlgRQFLEVELDQAREK 1471
Cdd:COG4913    667 EREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKE-----------LEQAEEELDELQDR 735

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2214681115 1472 YVQELAAVRTDAETHLAEMRQEAQSTSRELEVmtakyegakvkvleeRQRFQEERQKLTAQVEQLE 1537
Cdd:COG4913    736 LEAAEDLARLELRALLEERFAAALGDAVEREL---------------RENLEERIDALRARLNRAE 786
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
136-717 9.54e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.81  E-value: 9.54e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  136 DHEESLNLTEDLESFLEKVPYTHASTLSE--ELSPPSHQTKRKIRFLEiQRIASSSSENNFLSGSPSSpmgdilqtpqfq 213
Cdd:PRK02224   245 EHEERREELETLEAEIEDLRETIAETEREreELAEEVRDLRERLEELE-EERDDLLAEAGLDDADAEA------------ 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  214 mrrLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLAllnekqaassqepSELEELRGKNESLTVRLHET 293
Cdd:PRK02224   312 ---VEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLE-------------ERAEELREEAAELESELEEA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  294 LKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEhskasqewaekqarlENELSTALQDKKC 373
Cdd:PRK02224   376 REAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRER---------------EAELEATLRTARE 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  374 LEEKNEILqgklsqledqatrLQESPAPEKGEVLGDALQLDTL---KQEAAKLATDNTQLQTRVETLE--CERGKQEAQL 448
Cdd:PRK02224   441 RVEEAEAL-------------LEAGKCPECGQPVEGSPHVETIeedRERVEELEAELEDLEEEVEEVEerLERAEDLVEA 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  449 LAERSRFEDEKQQLASLIADLQssvsnlsqakeeleqasqaqgaqltaqltsmtglnATLQQRDQELASLKEQAKKEQAQ 528
Cdd:PRK02224   508 EDRIERLEERREDLEELIAERR-----------------------------------ETIEEKRERAEELRERAAELEAE 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  529 mlqtMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRqDHAQQLAIVAEAREA--SLRERDTARQQLETVEKE 606
Cdd:PRK02224   553 ----AEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEieRLREKREALAELNDERRE 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  607 KDAKLESLQQQLQAANDArdnaqTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKaEQQKTTEREK 686
Cdd:PRK02224   628 RLAEKRERKRELEAEFDE-----ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELE-ELEELRERRE 701

                          570       580       590
                   ....*....|....*....|....*....|.
gi 2214681115  687 VVQEKAQLQEQLRALEESLKITKGSLEEEKR 717
Cdd:PRK02224   702 ALENRVEALEALYDEAEELESMYGDLRAELR 732
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 521-814 9.84e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 51.11  E-value: 9.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  521 QAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEA----AKEQEATRQ----DHAQQ--------LAIVAE 584
Cdd:COG3096    289 ELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAAsdhlNLVQTALRQqekiERYQEdleelterLEEQEE 368

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  585 AREASLRERDTARQQLETVEKEKDakleSLQQQLQAANDARDNAQTSVTQAQQEKaelsQKIGELHACIEASHQEQRQVQ 664
Cdd:COG3096    369 VVEEAAEQLAEAEARLEAAEEEVD----SLKSQLADYQQALDVQQTRAIQYQQAV----QALEKARALCGLPDLTPENAE 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  665 ARVTELEAQlkaEQQKTTEREKVVQEKAQLQEQLRALEESLK-ITKGSLEEEKRRAADALKEQQCRATEMEAESRSL--- 740
Cdd:COG3096    441 DYLAAFRAK---EQQATEEVLELEQKLSVADAARRQFEKAYElVCKIAGEVERSQAWQTARELLRRYRSQQALAQRLqql 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  741 ------MEQREREQ-------KELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQhraeSECERLIREVESR 807
Cdd:COG3096    518 raqlaeLEQRLRQQqnaerllEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQR----SELRQQLEQLRAR 593


                   ....*..
gi 2214681115  808 QKRFEAR 814
Cdd:COG3096    594 IKELAAR 600
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1189-1321 1.09e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 50.63  E-value: 1.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1189 QALRaKAQDHSKAEEEWKAQVARGQQEAERkssliSSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLL 1268
Cdd:COG2433    380 EALE-ELIEKELPEEEPEAEREKEHEEREL-----TEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEA 453

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2214681115 1269 QVEtASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELasqaERAEEL 1321
Cdd:COG2433    454 RSE-ERREIRKDREISRLDREIERLERELEEERERIEELKRKL----ERLKEL 501
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 211-764 1.15e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.94  E-value: 1.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  211 QFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLA----LLNEKQAASSQEPSELEE-------L 279
Cdd:pfam01576  102 QQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSkerkLLEERISEFTSNLAEEEEkakslskL 181

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  280 RGKNESLTVRLHETLKQC----QNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQ----LQGAFNDLIEEHSKASQ 351
Cdd:pfam01576  182 KNKHEAMISDLEERLKKEekgrQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKkeeeLQAALARLEEETAQKNN 261

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  352 ----------EWAEKQARLENEL---STALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVlgdALQLDTLKQ 418
Cdd:pfam01576  262 alkkireleaQISELQEDLESERaarNKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEV---TELKKALEE 338

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  419 EAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLtaql 498
Cdd:pfam01576  339 ETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQL---- 414

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  499 tsmtglnatlqqrdQELASLKEQAKKEQaqmlqtmQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATrqdhAQQ 578
Cdd:pfam01576  415 --------------QELQARLSESERQR-------AELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSL----ESQ 469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  579 LAIVAEAREASLRERDTARQQLETVEKEKDakleSLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQ 658
Cdd:pfam01576  470 LQDTQELLQEETRQKLNLSTRLRQLEDERN----SLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEE 545

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  659 EQRQVQarvTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRAL---EESLKITKGSLEEEKRRAADALKEQQ-CRATEME 734
Cdd:pfam01576  546 GKKRLQ---RELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLlvdLDHQRQLVSNLEKKQKKFDQMLAEEKaISARYAE 622

                          570       580       590
                   ....*....|....*....|....*....|
gi 2214681115  735 AESRSLMEQREREQKELEQEKAGRKGLEAR 764
Cdd:pfam01576  623 ERDRAEAEAREKETRALSLARALEEALEAK 652
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 260-907 1.16e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.56  E-value: 1.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  260 ALLNEKQAASSQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAF 339
Cdd:pfam01576  447 SLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQL 526

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  340 NDL---IEEHSKASQEWAEKQARLENELSTALQdkkCLEEKNEilqgKLSQLEDQATRLQEspapekgEVLGDALQLDTL 416
Cdd:pfam01576  527 SDMkkkLEEDAGTLEALEEGKKRLQRELEALTQ---QLEEKAA----AYDKLEKTKNRLQQ-------ELDDLLVDLDHQ 592

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  417 KQeaakLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTA 496
Cdd:pfam01576  593 RQ----LVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMED 668

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  497 QLTSMTGLNATLQqrdqELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHA 576
Cdd:pfam01576  669 LVSSKDDVGKNVH----ELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKR 744

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  577 QQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEAS 656
Cdd:pfam01576  745 RQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEI 824

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  657 HQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAAD-------ALKEQQCR 729
Cdd:pfam01576  825 LAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEAriaqleeELEEEQSN 904

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  730 ATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQaETEALRHELAEATASQHRA-----ESECERLIREV 804
Cdd:pfam01576  905 TELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNK-ELKAKLQEMEGTVKSKFKSsiaalEAKIAQLEEQL 983

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  805 ESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEihsegqpgQQQSQLAQLHASLAKAIQQVQEKEVRAQK 884
Cdd:pfam01576  984 EQESRERQAANKLVRRTEKKLKEVLLQVEDERRHADQYKDQAE--------KGNSRMKQLKRQLEEAEEEASRANAARRK 1055

                          650       660
                   ....*....|....*....|...
gi 2214681115  885 LVDDLSALQEKMAATNKEVACLK 907
Cdd:pfam01576 1056 LQRELDDATESNESMNREVSTLK 1078
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1278-1694 1.17e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 1.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1278 RAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELL 1357
Cdd:PRK03918   162 NAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1358 PAKhlcqQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERaaqqLRAEKASYAEQLSMLK 1437
Cdd:PRK03918   242 ELE----KELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK----LSEFYEEYLDELREIE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1438 KAHGLLAEENRGLGER-ANLGRQFLEV-ELDQAREKYVQELAAVRTDAETH------LAEMRQ-EAQSTSRELEVMTAKY 1508
Cdd:PRK03918   314 KRLSRLEEEINGIEERiKELEEKEERLeELKKKLKELEKRLEELEERHELYeeakakKEELERlKKRLTGLTPEKLEKEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1509 EGAKvkvlEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSK----------KLTEHDQASKVQQ--QKLKAFQAQRG 1576
Cdd:PRK03918   394 EELE----KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrELTEEHRKELLEEytAELKRIEKELK 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1577 ESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQ 1656
Cdd:PRK03918   470 EIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELE 549

                          410       420       430
                   ....*....|....*....|....*....|....*...
gi 2214681115 1657 qaglKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLG 1694
Cdd:PRK03918   550 ----KLEELKKKLAELEKKLDELEEELAELLKELEELG 583
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
1571-1693 1.20e-05

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 49.66  E-value: 1.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1571 FQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEhYKLQMEKAKTHYDAKKQQ---NQKLQEQ----LQDLEELQKENKE 1643
Cdd:COG1566     81 LQAALAQAEAQLAAAEAQLARLEAELGAEAEIAA-AEAQLAAAQAQLDLAQRElerYQALYKKgavsQQELDEARAALDA 159

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1644 LRSEAERLGRELQQAGLKTKEAEQTcRHLTAQVRSLEAQVAHADQQLRDL 1693
Cdd:COG1566    160 AQAQLEAAQAQLAQAQAGLREEEEL-AAAQAQVAQAEAALAQAELNLART 208
HpsJ_fam NF038305
HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the ...
 503-619 1.30e-05

HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the biosynthesis or secretion of an extracellular polysaccharide shared by many Cyanobacteria.


Pssm-ID: 468465 [Multi-domain]  Cd Length: 230  Bit Score: 48.73  E-value: 1.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  503 GLNATLQQRDQELASLKEQAKKEQAQmLQTMQEQEQAAQGlRQQVEQLSSSLKLKEQQLEEAAKEQEaTRQDHAQQLAIV 582
Cdd:NF038305    98 HLNNTRRLSTQALQQINQQAGQQETQ-LQQQLNQLQAQTS-PQQLNQLLKSEQKQGQALASGQLPEE-QKEQLQQFKSNP 174

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 2214681115  583 AEAREASLRERDTARQQLETVEKEkdAKLESLQQQLQ 619
Cdd:NF038305   175 QALDKFLAQQLTQIRTQAEEAEKQ--ARLEALKSSLR 209
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1117-1667 1.31e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 50.74  E-value: 1.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1117 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1196
Cdd:pfam02463  245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1197 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERL---RLLQVETA 1273
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKeeeLELKSEEE 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1274 SNSARAAERSSALREEVQSLREEVEKQRVVSENSRQ-ELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQAL 1352
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEEESIElKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1353 VSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGEL--GSLRQKIVEQERAAQQLRAEKASYA 1430
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAveNYKVAISTAVIVEVSATADEVEERQ 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1431 EQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQE-AQSTSRELEVMTAKYE 1509
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGiLKDTELTKLKESAKAK 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1510 GAKVKVLEERQRFQEERQKLTAQVEQLevfQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQL 1589
Cdd:pfam02463  645 ESGLRKGVSLEEGLAEKSEVKASLSEL---TKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2214681115 1590 NELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQ 1667
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQ 799
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1452-1738 1.47e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.42  E-value: 1.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1452 ERANLGRQFLEVELDQAREKYVQELAAV--RTDAETH--LAEMRQEAQSTSRELEVMTAKYEGAK------VKVLEERQR 1521
Cdd:PRK02224   169 ERASDARLGVERVLSDQRGSLDQLKAQIeeKEEKDLHerLNGLESELAELDEEIERYEEQREQARetrdeaDEVLEEHEE 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1522 FQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQ 1601
Cdd:PRK02224   249 RREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRD 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1602 AaehyklqMEKAKTHYDAKKQQNQKLQEQLQDLEElqkENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEA 1681
Cdd:PRK02224   329 R-------LEECRVAAQAHNEEAESLREDADDLEE---RAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRE 398

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2214681115 1682 QVAHADQQLRDLGKFQVATDALKSREPQVKPQLDLSIDSLDLSLEEGTPCSVASKLP 1738
Cdd:PRK02224   399 RFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCP 455
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 856-1087 1.69e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  856 QQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEvaclktlvLKAGEQQETASLELLKEPPRAANRA 935
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR--------IRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  936 SDQLGEQQgrpfssthAAVKAMEREAEQMGgeleRLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKA 1015
Cdd:COG4942     96 RAELEAQK--------EELAELLRALYRLG----RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA 163

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2214681115 1016 ELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKE 1087
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
PRK12704 PRK12704
phosphodiesterase; Provisional
 558-756 1.75e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 49.78  E-value: 1.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  558 EQQLEEAAKEQEATRQDhaqqlaIVAEAREaslrERDTARQQLETVEKEKDAKLESLQQQLqaandardnaqtsvtqaQQ 637
Cdd:PRK12704    41 KRILEEAKKEAEAIKKE------ALLEAKE----EIHKLRNEFEKELRERRNELQKLEKRL-----------------LQ 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  638 EKAELSQKIGELhacieashqEQRqvQARVTELEAQLKAEQQKTTEREKVVQEKaqLQEQLRALEESLKITKgslEEEKR 717
Cdd:PRK12704    94 KEENLDRKLELL---------EKR--EEELEKKEKELEQKQQELEKKEEELEEL--IEEQLQELERISGLTA---EEAKE 157

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 2214681115  718 RAADALKEqqcratEMEAESRSLMEQREREQKELEQEKA 756
Cdd:PRK12704   158 ILLEKVEE------EARHEAAVLIKEIEEEAKEEADKKA 190
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1158-1349 1.78e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.30  E-value: 1.78e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1158 KALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQ--VARGQQEAERKSSLISSLEE---EVSI 1232
Cdd:COG4913    610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEidVASAEREIAELEAELERLDAssdDLAA 689

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1233 LNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEvqsLREEVEKQRvvsensRQELA 1312
Cdd:COG4913    690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLE---LRALLEERF------AAALG 760

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 2214681115 1313 SQAER--AEELGQELKAWQEKFFQKEQALSALQLEHTST 1349
Cdd:COG4913    761 DAVERelRENLEERIDALRARLNRAEEELERAMRAFNRE 799
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
385-803 1.90e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.77  E-value: 1.90e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  385 LSQLEDQATRLQESPApEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLE---------CERGKQEAQLLAERSRF 455
Cdd:COG4717     70 LKELKELEEELKEAEE-KEEEYAELQEELEELEEELEELEAELEELREELEKLEkllqllplyQELEALEAELAELPERL 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  456 EDEKQQLASlIADLQSSVSNLSQAKEELEQASQAQGAQLT-AQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQ 534
Cdd:COG4717    149 EELEERLEE-LRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEE 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  535 -----EQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDA 609
Cdd:COG4717    228 eleqlENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEEL 307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  610 KLESLQQQLQAA--NDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKV 687
Cdd:COG4717    308 QALPALEELEEEelEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEEL 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  688 VQeKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQcrATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQ 767
Cdd:COG4717    388 RA-ALEQAEEYQELKEELEELEEQLEELLGELEELLEALD--EEELEEELEELEEELEELEEELEELREELAELEAELEQ 464

                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 2214681115  768 LEEAhqaetealrHELAEATASQHRAESECERLIRE 803
Cdd:COG4717    465 LEED---------GELAELLQELEELKAELRELAEE 491
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 412-816 1.93e-05

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 50.18  E-value: 1.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  412 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASL---------IADLQSSVSNLSQAKEE 482
Cdd:PRK10246   427 RLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVkticeqearIKDLEAQRAQLQAGQPC 506

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  483 LEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQ---MLQTMQEQEQAAQGLRQQVEQLSS------- 552
Cdd:PRK10246   507 PLCGSTSHPAVEAYQALEPGVNQSRLDALEKEVKKLGEEGAALRGQldaLTKQLQRDESEAQSLRQEEQALTQqwqavca 586

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  553 SLKLKEQQLEEAAKEQEAtRQDHAQQLAIVAEARE------ASLRERDTARQQLETVEKEKDAKLESLQQQLQAAND--- 623
Cdd:PRK10246   587 SLNITLQPQDDIQPWLDA-QEEHERQLRLLSQRHElqgqiaAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEeas 665

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  624 ---ARDNAQTSVTQAQQEKAELSQKIGELHACIE--------------ASHQEQRQVQARVTELEAQLKAEQQKTTerek 686
Cdd:PRK10246   666 wlaTRQQEAQSWQQRQNELTALQNRIQQLTPLLEtlpqsddlphseetVALDNWRQVHEQCLSLHSQLQTLQQQDV---- 741

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  687 vvQEKAQLQEQLRALEESLkitKGSLEEEKRRAADALkeqqcrateMEAESRSLMEQRereQKELEQEKAGRKGLEARIQ 766
Cdd:PRK10246   742 --LEAQRLQKAQAQFDTAL---QASVFDDQQAFLAAL---------LDEETLTQLEQL---KQNLENQRQQAQTLVTQTA 804

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 2214681115  767 QLEEAHQAETEALRHELAEATASQHRAESECERLiREVESRQKrfEARQQ 816
Cdd:PRK10246   805 QALAQHQQHRPDGLDLTVTVEQIQQELAQLAQQL-RENTTRQG--EIRQQ 851
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1378-1682 2.34e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.95  E-value: 2.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1378 REELEQSKQAAGGLQAELMRAQRELGELGSlRQKIVEQE-----------RAAQQLRAEKASYAEQLSMLKKAhgllAEE 1446
Cdd:COG3096    291 RRELFGARRQLAEEQYRLVEMARELEELSA-RESDLEQDyqaasdhlnlvQTALRQQEKIERYQEDLEELTER----LEE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1447 NRGLGERANLGRQFLEVELDQAREKyVQELAAVRTDAETHLAEMR------QEAQSTSRELEVMTAKYEGAKVKVLEERQ 1520
Cdd:COG3096    366 QEEVVEEAAEQLAEAEARLEAAEEE-VDSLKSQLADYQQALDVQQtraiqyQQAVQALEKARALCGLPDLTPENAEDYLA 444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1521 RFQEERQKLTAQVEQLEV------FQREQTKQVEELSKKL---TEHDQASKVQQQKLKAFQAQRGESQQEVQrLQTQLNE 1591
Cdd:COG3096    445 AFRAKEQQATEEVLELEQklsvadAARRQFEKAYELVCKIageVERSQAWQTARELLRRYRSQQALAQRLQQ-LRAQLAE 523

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1592 LQAQLSQKEQAAEhyklqmekakthydAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRH 1671
Cdd:COG3096    524 LEQRLRQQQNAER--------------LLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQ 589

                          330
                   ....*....|.
gi 2214681115 1672 LTAQVRSLEAQ 1682
Cdd:COG3096    590 LRARIKELAAR 600
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 354-570 2.41e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.41e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  354 AEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTR 433
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  434 VETLECERGKQ--EAQLLAERSRFE-----DEKQQLASLIADLQSSVSNLSQAKEELEQASQ---AQGAQLTAQLTSMTG 503
Cdd:COG4942     99 LEAQKEELAELlrALYRLGRQPPLAlllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAelaALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2214681115  504 LNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEA 570
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 412-640 2.45e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  412 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLlaerSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQG 491
Cdd:COG4942     28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI----AALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  492 AQLTAQLTSMtglnATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAT 571
Cdd:COG4942    104 EELAELLRAL----YRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115  572 RQDHAQQLAIVAEAREaslrERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKA 640
Cdd:COG4942    180 LAELEEERAALEALKA----ERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1461-1653 2.52e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1461 LEVELDQAREKyVQELAAVRTDAETHlAEMRQEAQSTSRELEVMTAKYEGAKVKVLEER-QRFQEERQKLTAQVEQLEVF 1539
Cdd:COG4913    240 AHEALEDAREQ-IELLEPIRELAERY-AAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEAR 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1540 QREQTKQVEELSKKLTEHDQASKvqqQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQA-AEHYKLQMEKAKTHYD 1618
Cdd:COG4913    318 LDALREELDELEAQIRGNGGDRL---EQLEREIERLERELEERERRRARLEALLAALGLPLPAsAEEFAALRAEAAALLE 394

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 2214681115 1619 AKKQQNQKLQEQL----QDLEELQKENKELRSEAERLGR 1653
Cdd:COG4913    395 ALEEELEALEEALaeaeAALRDLRRELRELEAEIASLER 433
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
630-796 2.61e-05

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 49.10  E-value: 2.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  630 TSVTQAQQEKAELSQKIGELHacIEASHQEQRQVQA-RVTELEAQLKAEQQKttEREKVVQEKAQLQEQLRAL-EESLKI 707
Cdd:COG2268    195 AEIIRDARIAEAEAERETEIA--IAQANREAEEAELeQEREIETARIAEAEA--ELAKKKAEERREAETARAEaEAAYEI 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  708 TkgslEEEKRRAADALKEQQCRATEMEAEsrslmeQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHE-LAEA 786
Cdd:COG2268    271 A----EANAEREVQRQLEIAEREREIELQ------EKEAEREEAELEADVRKPAEAEKQAAEAEAEAEAEAIRAKgLAEA 340

                          170
                   ....*....|
gi 2214681115  787 TASQHRAESE 796
Cdd:COG2268    341 EGKRALAEAW 350
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1477-1706 2.72e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 2.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1477 AAVRTDAETHLAEMRQEAQSTSRELevmtAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTE 1556
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKEL----AALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1557 HDQASKVQQQKLKAF--QAQRGE---------SQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQ 1625
Cdd:COG4942     95 LRAELEAQKEELAELlrALYRLGrqpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1626 KLQEQLQDLEELQKENKELRSEAERLGRELQQaglKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKS 1705
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEK---ELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251


                   .
gi 2214681115 1706 R 1706
Cdd:COG4942    252 K 252
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 685-1474 2.86e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 49.35  E-value: 2.86e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  685 EKVVQEKAQlqeQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEkagRKGLEAR 764
Cdd:pfam15921   77 ERVLEEYSH---QVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDL---RNQLQNT 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  765 IQQLEEAHQAETEALRHELAEATASQHRAESEcERLIREVESRQKRFEarqqEEARYGAMFQEQLMALKGEKTGQEVQEE 844
Cdd:pfam15921  151 VHELEAAKCLKEDMLEDSNTQIEQLRKMMLSH-EGVLQEIRSILVDFE----EASGKKIYEHDSMSTMHFRSLGSAISKI 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  845 AVEIHSE-----GQPGQQQSQLAQLHASLAKAIQQV-QEKEVRAQKLVDD----LSALQEKMAATNKEVACLKTlvlkag 914
Cdd:pfam15921  226 LRELDTEisylkGRIFPVEDQLEALKSESQNKIELLlQQHQDRIEQLISEheveITGLTEKASSARSQANSIQS------ 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  915 eqqetaSLELLKEPPRAANrasdQLGEQQGRPFSSTHAAVKAMEREAEQM-GGELERLRAALIKSQgqqqeergqqerev 993
Cdd:pfam15921  300 ------QLEIIQEQARNQN----SMYMRQLSDLESTVSQLRSELREAKRMyEDKIEELEKQLVLAN-------------- 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  994 ARLTQERGQaQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQT 1073
Cdd:pfam15921  356 SELTEARTE-RDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEAL 434

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1074 LEQLKIQlVKKEKEHPAGGASGEDASGPGTQSETAgKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACR 1153
Cdd:pfam15921  435 LKAMKSE-CQGQMERQMAAIQGKNESLEKVSSLTA-QLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAI 512

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1154 AEQDKALETLQGQLEEKARELGHNQAAS---ASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEV 1230
Cdd:pfam15921  513 EATNAEITKLRSRVDLKLQELQHLKNEGdhlRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEK 592

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1231 SILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREevqsLREEVEKQRVVSENSRQE 1310
Cdd:pfam15921  593 AQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKD----IKQERDQLLNEVKTSRNE 668

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1311 LASQAERAEELGQELKAWQEKFfqkEQALSALQLEHTSTQalvSELlpakhlcqqlqAEQAAAEKRFREELEQSKQAAGG 1390
Cdd:pfam15921  669 LNSLSEDYEVLKRNFRNKSEEM---ETTTNKLKMQLKSAQ---SEL-----------EQTRNTLKSMEGSDGHAMKVAMG 731

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1391 LQAELMrAQRelGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLA-EENRGLGERANLGRQ---------F 1460
Cdd:pfam15921  732 MQKQIT-AKR--GQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVAtEKNKMAGELEVLRSQerrlkekvaN 808

                          810
                   ....*....|....
gi 2214681115 1461 LEVELDQAREKYVQ 1474
Cdd:pfam15921  809 MEVALDKASLQFAE 822
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1211-1654 2.94e-05

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 49.35  E-value: 2.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1211 RGQQEAERKSS-LISSLEEEVSilnrQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSAL--- 1286
Cdd:pfam05557   27 RARIELEKKASaLKRQLDRESD----RNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQLada 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1287 REEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcqql 1366
Cdd:pfam05557  103 REVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAEAEQRI---------- 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1367 qaeqaaaekrfrEELEQSKQAAGGLQAELMRAQRELGelgslrqKIVEQERAAQQLRAEKasyaEQLSMLKKAHGLLAEE 1446
Cdd:pfam05557  173 ------------KELEFEIQSQEQDSEIVKNSKSELA-------RIPELEKELERLREHN----KHLNENIENKLLLKEE 229

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1447 NRGLgeRANLGRQfleveldqarEKYVQELAAVRTDAEtHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQR---FQ 1523
Cdd:pfam05557  230 VEDL--KRKLERE----------EKYREEAATLELEKE-KLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQLQQReivLK 296

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1524 EERQKLTAQVEQLEVFQRE-------QTKQVEELSKKLTEHD-QASKVQQQKLKAFQAQRG------------------- 1576
Cdd:pfam05557  297 EENSSLTSSARQLEKARREleqelaqYLKKIEDLNKKLKRHKaLVRRLQRRVLLLTKERDGyrailesydkeltmsnysp 376

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1577 -------ESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQL--QDLEELQKENKELRSE 1647
Cdd:pfam05557  377 qllerieEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLADPSYskEEVDSLRRKLETLELE 456


                   ....*..
gi 2214681115 1648 AERLGRE 1654
Cdd:pfam05557  457 RQRLREQ 463
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 572-1425 3.07e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.57  E-value: 3.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  572 RQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLES---LQQQLQAANDARDNAQTSVtqAQQEKAElsqkige 648
Cdd:COG3096    280 RRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSAResdLEQDYQAASDHLNLVQTAL--RQQEKIE------- 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  649 lhacieashqeqrQVQARVTELEAQLKAEQQKTTEREkvvQEKAQLQEQLRALEESLKITKGSLEEEKRraadALKEQQC 728
Cdd:COG3096    351 -------------RYQEDLEELTERLEEQEEVVEEAA---EQLAEAEARLEAAEEEVDSLKSQLADYQQ----ALDVQQT 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  729 RATEMEAESRSLmeqrEREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRH-----ELAEATASQHRAESE-CERLIR 802
Cdd:COG3096    411 RAIQYQQAVQAL----EKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLEleqklSVADAARRQFEKAYElVCKIAG 486

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  803 EVESRQKRFEARQQ-EEARYGAMFQEQLMALKgektgQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVR 881
Cdd:COG3096    487 EVERSQAWQTARELlRRYRSQQALAQRLQQLR-----AQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAE 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  882 AQKLVDDLSALQEkmAATNKEVACLKTLVLKAGEQQETASlellKEPP-RAANRASDQLGEQQGRPFSSTHAAVKAMERE 960
Cdd:COG3096    562 LEAQLEELEEQAA--EAVEQRSELRQQLEQLRARIKELAA----RAPAwLAAQDALERLREQSGEALADSQEVTAAMQQL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  961 aeqmggeLERLRAALIkSQGQQQEERGQQEREVARLTQERGQAQADLAQekaakaeLEMRLQNTLNEQRVEFAALQEA-- 1038
Cdd:COG3096    636 -------LEREREATV-ERDELAARKQALESQIERLSQPGGAEDPRLLA-------LAERLGGVLLSEIYDDVTLEDApy 700

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1039 -------LAHAL---------------------------------------TEKEGTDqeLAKLRGQE------------ 1060
Cdd:COG3096    701 fsalygpARHAIvvpdlsavkeqlagledcpedlyliegdpdsfddsvfdaEELEDAV--VVKLSDRQwrysrfpevplf 778

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1061 ---------AAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASgedasgPGTQSETAGKTDaPGPELQALRAEISKLEQQ 1131
Cdd:COG3096    779 graarekrlEELRAERDELAEQYAKASFDVQKLQRLHQAFSQF------VGGHLAVAFAPD-PEAELAALRQRRSELERE 851

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1132 cqqqqqqveglthsLKSERACRAEQDKALETLQGQLEEKARELGHnqaASASAQRELQALRAKAQDHSKAEEEWKAQVAR 1211
Cdd:COG3096    852 --------------LAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQ---ANLLADETLADRLEELREELDAAQEAQAFIQQ 914

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1212 GQQEAERksslissLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQ 1291
Cdd:COG3096    915 HGKALAQ-------LEPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAVGLLGENSDLNE 987

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1292 SLREEVEkqrvvsensrqelasQAERA-EELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLP-----AKHLCQQ 1365
Cdd:COG3096    988 KLRARLE---------------QAEEArREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQeleelGVQADAE 1052

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1366 LQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRelgELGSLRQKIVEQERAAQQLRAE 1425
Cdd:COG3096   1053 AEERARIRRDELHEELSQNRSRRSQLEKQLTRCEA---EMDSLQKRLRKAERDYKQEREQ 1109
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1397-1658 3.16e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 3.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1397 RAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAhgllaEENRGLGERANLGRQFLEVELDQARekyVQEL 1476
Cdd:COG4913    229 ALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERL-----AELEYLRAALRLWFAQRRLELLEAE---LEEL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1477 AAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKvkvleerqrfqeerqklTAQVEQLEvfqreqtKQVEELSKKLTE 1556
Cdd:COG4913    301 RAELARLEAELERLEARLDALREELDELEAQIRGNG-----------------GDRLEQLE-------REIERLERELEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1557 HDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEhyklqmekakthyDAKKQQNQKLQEQLQDLEE 1636
Cdd:COG4913    357 RERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALE-------------EALAEAEAALRDLRRELRE 423

                          250       260
                   ....*....|....*....|..
gi 2214681115 1637 LQKENKELRSEAERLGRELQQA 1658
Cdd:COG4913    424 LEAEIASLERRKSNIPARLLAL 445
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 313-649 3.43e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.20  E-value: 3.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  313 QLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQA 392
Cdd:TIGR00618  539 QLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALL 618

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  393 TRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQ------------ 460
Cdd:TIGR00618  619 RKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQsekeqltywkem 698

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  461 --QLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQltsmtglNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQ 538
Cdd:TIGR00618  699 laQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAR-------EDALNQSLKELMHQARTVLKARTEAHFNNNEEVT 771

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  539 AAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQL 618
Cdd:TIGR00618  772 AALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQL 851

                          330       340       350
                   ....*....|....*....|....*....|.
gi 2214681115  619 QAANDARDNAQtsvtQAQQEKAELSQKIGEL 649
Cdd:TIGR00618  852 LKYEECSKQLA----QLTQEQAKIIQLSDKL 878
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 319-699 3.79e-05

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 48.90  E-value: 3.79e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  319 GDLSFKVREFANHLQQLQGAFNDLIEEHS-KASQEWAEKQARLENELSTAlqDKKCLEEKNEILQGKLSQLEDQATRLQ- 396
Cdd:pfam13166   88 GEESIEIQEKIAKLKKEIKDHEEKLDAAEaNLQKLDKEKEKLEADFLDEC--WKKIKRKKNSALSEALNGFKYEANFKSr 165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  397 -----ESPAPEKGEVLGDAlqldtlkQEAAKLATDNTQLQTRVETLECerGKQEAQLLAERSRFEDEKQQLASLIADLQS 471
Cdd:pfam13166  166 llreiEKDNFNAGVLLSDE-------DRKAALATVFSDNKPEIAPLTF--NVIDFDALEKAEILIQKVIGKSSAIEELIK 236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  472 SVSNLSQAKEELEQASQAQG----------AQLTAQLTSMTGLNATLQQRD-QELASLKEQAKKEQAQMLQTMQEQEQAA 540
Cdd:pfam13166  237 NPDLADWVEQGLELHKAHLDtcpfcgqplpAERKAALEAHFDDEFTEFQNRlQKLIEKVESAISSLLAQLPAVSDLASLL 316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  541 QGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIvaeareaslrerdtarqqletveKEKDAKLESLQQQLQA 620
Cdd:pfam13166  317 SAFELDVEDIESEAEVLNSQLDGLRRALEAKRKDPFKSIEL-----------------------DSVDAKIESINDLVAS 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  621 AND--ARDNAQTSVTQAQQEKAELS---QKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQkttEREKVVQEKAQLQ 695
Cdd:pfam13166  374 INEliAKHNEITDNFEEEKNKAKKKlrlHLVEEFKSEIDEYKDKYAGLEKAINSLEKEIKNLEA---EIKKLREEIKELE 450


                   ....
gi 2214681115  696 EQLR 699
Cdd:pfam13166  451 AQLR 454
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 577-954 4.50e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.06  E-value: 4.50e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  577 QQLAIVAEAREASLRERDTARQQ-LETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGElhaciea 655
Cdd:NF012221  1503 KTLKLTAKAGSNRLEFKGTGHNDgLGYILDNVVATSESSQQADAVSKHAKQDDAAQNALADKERAEADRQRLE------- 1575

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  656 shQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGsleeekrraADALKEQQCRATEMEA 735
Cdd:NF012221  1576 --QEKQQQLAAISGSQSQLESTDQNALETNGQAQRDAILEESRAVTKELTTLAQG---------LDALDSQATYAGESGD 1644

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  736 ESRSLMEQR--EREQKELEQEKagrKGLEARIQQLEEAHQAETEALRHELAEATASQHRAesecERLIREVESRQKrfEA 813
Cdd:NF012221  1645 QWRNPFAGGllDRVQEQLDDAK---KISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQG----EQNQANAEQDID--DA 1715

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  814 RQQEEARYGAMFQEQLMALKGEKTGQEVQEEAveihseGQPGQQQSQLAQLHASLAKAiqqvqekevraqklvDDLSALQ 893
Cdd:NF012221  1716 KADAEKRKDDALAKQNEAQQAESDANAAANDA------QSRGEQDASAAENKANQAQA---------------DAKGAKQ 1774

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2214681115  894 EKMAATNKEVACLKTLVLKAGEQQETA--SLELLKEPPRAAN-RASDQLGEQQGRPFSSTHAAV 954
Cdd:NF012221  1775 DESDKPNRQGAAGSGLSGKAYSVEGVAepGSHINPDSPAAADgRFSEGLTEQEQEALEGATNAV 1838
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 511-834 4.60e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 48.80  E-value: 4.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  511 RDQELASLKEQAKKEQAQMLQT---MQEQEQAAQGLRQQV------------EQLSSSLKLKEQQLEEAAKEQEATRQDH 575
Cdd:COG3096    783 REKRLEELRAERDELAEQYAKAsfdVQKLQRLHQAFSQFVgghlavafapdpEAELAALRQRRSELERELAQHRAQEQQL 862

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  576 AQQLaivaeareaslrerDTARQQLETVEK-EKDAKL---ESLQQQLQAANDARDNAQtsvtQAQQEKAELSQKIGELH- 650
Cdd:COG3096    863 RQQL--------------DQLKEQLQLLNKlLPQANLladETLADRLEELREELDAAQ----EAQAFIQQHGKALAQLEp 924

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  651 --ACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQ--------EKAQLQEQLRALEESLKITKGSLEEEKRRAA 720
Cdd:COG3096    925 lvAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQrrphfsyeDAVGLLGENSDLNEKLRARLEQAEEARREAR 1004

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  721 DALKEQQCRATEMEAESRSLMEQREREQKELeqekagrKGLEARIQQLEEAHQAETEAL----RHELAEAtASQHRA--- 793
Cdd:COG3096   1005 EQLRQAQAQYSQYNQVLASLKSSRDAKQQTL-------QELEQELEELGVQADAEAEERarirRDELHEE-LSQNRSrrs 1076

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 2214681115  794 ESECERLIREVESRQKRFEARQQEEaRYGAMFQEQLMALKG 834
Cdd:COG3096   1077 QLEKQLTRCEAEMDSLQKRLRKAER-DYKQEREQVVQAKAG 1116
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1375-1716 5.14e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.52  E-value: 5.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1375 KRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGER- 1453
Cdd:PRK03918   182 EKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKi 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1454 ANLGRQFLEVELD-QAREKYVQELAAVRTDAETHlaemrqeaqstsRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQ 1532
Cdd:PRK03918   262 RELEERIEELKKEiEELEEKVKELKELKEKAEEY------------IKLSEFYEEYLDELREIEKRLSRLEEEINGIEER 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1533 VEQLEvfqrEQTKQVEELSKKLTEHDQASKVQQQKLKAFQaqrgesqqEVQRLQTQLNELQAQLSQKEqaAEHYKLQMEK 1612
Cdd:PRK03918   330 IKELE----EKEERLEELKKKLKELEKRLEELEERHELYE--------EAKAKKEELERLKKRLTGLT--PEKLEKELEE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1613 AKThydAKKQQNQKLQEQLQDLEELQKENKELRSEAERL----------GRELQQaglktKEAEQTCRHLTAQVRSLEAQ 1682
Cdd:PRK03918   396 LEK---AKEEIEEEISKITARIGELKKEIKELKKAIEELkkakgkcpvcGRELTE-----EHRKELLEEYTAELKRIEKE 467

                          330       340       350
                   ....*....|....*....|....*....|....
gi 2214681115 1683 VAHADQQLRDLGKFQVATDALKSREPQVKPQLDL 1716
Cdd:PRK03918   468 LKEIEEKERKLRKELRELEKVLKKESELIKLKEL 501
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 608-790 5.52e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.90  E-value: 5.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  608 DAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKV 687
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  688 VQEK--------------------------AQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLM 741
Cdd:COG3883     95 LYRSggsvsyldvllgsesfsdfldrlsalSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE 174

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2214681115  742 EQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQ 790
Cdd:COG3883    175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAA 223
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1534-1704 5.98e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.09  E-value: 5.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1534 EQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRG---------ESQQEVQRLQTQLNELQAQLSQKEQAAE 1604
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGlvdlseeakLLLQQLSELESQLAEARAELAEAEARLA 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1605 HYKLQMEKAKTH---------YDAKKQQNQKLQEQLQDLEELQKEN----KELRSEAERLGRELQQAGLKTK-EAEQTCR 1670
Cdd:COG3206    244 ALRAQLGSGPDAlpellqspvIQQLRAQLAELEAELAELSARYTPNhpdvIALRAQIAALRAQLQQEAQRILaSLEAELE 323

                          170       180       190
                   ....*....|....*....|....*....|....
gi 2214681115 1671 HLTAQVRSLEAQVAHADQQLRDLGKFQVATDALK 1704
Cdd:COG3206    324 ALQAREASLQAQLAQLEARLAELPELEAELRRLE 357
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
374-551 6.18e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.09  E-value: 6.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  374 LEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNT--QLQTRVETLECERGKQEAQLLAE 451
Cdd:COG3206    210 LSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPViqQLRAQLAELEAELAELSARYTPN 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  452 RSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQ 531
Cdd:COG3206    290 HPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYES 369

                          170       180
                   ....*....|....*....|
gi 2214681115  532 TMQEQEQAAQGLRQQVEQLS 551
Cdd:COG3206    370 LLQRLEEARLAEALTVGNVR 389
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 244-923 7.61e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.19  E-value: 7.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  244 EKDAQIAMMQQRIDHLALLNEKQAASSQEPseleelrgkneslTVRLHETLKQCQNLKTEKSQMDRKISQLSEengDLSF 323
Cdd:pfam15921   82 EYSHQVKDLQRRLNESNELHEKQKFYLRQS-------------VIDLQTKLQEMQMERDAMADIRRRESQSQE---DLRN 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  324 KVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLE---NELSTALQDKKCLEEKNEILQGKLSQLEDQAT------- 393
Cdd:pfam15921  146 QLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEgvlQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLgsaiski 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  394 --RLQESPAPEKGEVLGDALQLDTLKQEAaklatdntqlQTRVETLECERGKQEAQLLAERsrfEDEKQQLASLIADLQS 471
Cdd:pfam15921  226 lrELDTEISYLKGRIFPVEDQLEALKSES----------QNKIELLLQQHQDRIEQLISEH---EVEITGLTEKASSARS 292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  472 SVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQE--------LASLKEQAKKEQAQMLQTMQEQEQAAQ-- 541
Cdd:pfam15921  293 QANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREakrmyedkIEELEKQLVLANSELTEARTERDQFSQes 372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  542 -GLRQQVEQLSSSLKLKEQQLeEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLE----TVEKEKDAKLESLQQ 616
Cdd:pfam15921  373 gNLDDQLQKLLADLHKREKEL-SLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEallkAMKSECQGQMERQMA 451

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  617 QLQAANDARDNAQTSVTQAQQEKAELSQKIGELHA---CIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQ 693
Cdd:pfam15921  452 AIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAkkmTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQ 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  694 LQEQLRALEESLKITKGSLE------EEKRRAADALKEQQCRATE-----------MEAESRSLMEQREREQKELEQEKA 756
Cdd:pfam15921  532 ELQHLKNEGDHLRNVQTECEalklqmAEKDKVIEILRQQIENMTQlvgqhgrtagaMQVEKAQLEKEINDRRLELQEFKI 611

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  757 GRKGLEARIQQLeEAHQAETEALRHELAEATASQHRA----ESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMAL 832
Cdd:pfam15921  612 LKDKKDAKIREL-EARVSDLELEKVKLVNAGSERLRAvkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEM 690

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  833 KGEKTGQEVQEEAVEIHSEgqpgQQQSQLAQLHASLAKAI-------QQVQEKEVRAQKLVDDLSALQEKMAATNKEVAC 905
Cdd:pfam15921  691 ETTTNKLKMQLKSAQSELE----QTRNTLKSMEGSDGHAMkvamgmqKQITAKRGQIDALQSKIQFLEEAMTNANKEKHF 766

                          730
                   ....*....|....*...
gi 2214681115  906 LKTLVLKAGEQQETASLE 923
Cdd:pfam15921  767 LKEEKNKLSQELSTVATE 784
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 469-736 8.34e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 48.13  E-value: 8.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  469 LQSSVSNLSQAKEELEqasQAQGAQLTAQLTSMTGLNATLQQRDQELASLkEQAKKEQaqmlQTMQEQEQAAQGLRQQVE 548
Cdd:PRK10929    18 YAATAPDEKQITQELE---QAKAAKTPAQAEIVEALQSALNWLEERKGSL-ERAKQYQ----QVIDNFPKLSAELRQQLN 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  549 QLSSSLKLKEQQLEEAAKEQEaTRQDHAQQLaivAEAREASlRERDTARQ------QLETVEKEKDAKLESLQQQLQAAN 622
Cdd:PRK10929    90 NERDEPRSVPPNMSTDALEQE-ILQVSSQLL---EKSRQAQ-QEQDRAREisdslsQLPQQQTEARRQLNEIERRLQTLG 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  623 dardNAQTSVTQAQ--QEKAELSQKigelhacieashqeqrqvQARVTELE-AQLKA--EQQKTTEREKVVQEKA-QLQE 696
Cdd:PRK10929   165 ----TPNTPLAQAQltALQAESAAL------------------KALVDELElAQLSAnnRQELARLRSELAKKRSqQLDA 222

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 2214681115  697 QLRALEESLKITKgsleeeKRRAADALKEqqcraTEMEAE 736
Cdd:PRK10929   223 YLQALRNQLNSQR------QREAERALES-----TELLAE 251
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 655-904 8.48e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 8.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  655 ASHQEQRQVQARVTELEAQLKAEQQkttEREKVVQEKAQLQEQLRALEESLKitkgsleeekrRAADALKEQQCRATEME 734
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEK---ELAALKKEEKALLKQLAALERRIA-----------ALARRIRALEQELAALE 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  735 AESRSLMEQREREQKELEQEkagRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESEcERLIREVESRQKRFEAR 814
Cdd:COG4942     83 AELAELEKEIAELRAELEAQ---KEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYL-KYLAPARREQAEELRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  815 QQEEARYGAMFQEQLMALKGEKTGQEVQEEAVeihsEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQE 894
Cdd:COG4942    159 LAELAALRAELEAERAELEALLAELEEERAAL----EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234

                          250
                   ....*....|
gi 2214681115  895 KMAATNKEVA 904
Cdd:COG4942    235 EAAAAAERTP 244
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1167-1690 8.49e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.81  E-value: 8.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1167 LEEKARElGHNQAASASAQRELQALRAKAQD-----HSKAEEEWKAQVARGQQEAERK-SSLISSLEEEVSILNRQVLEK 1240
Cdd:pfam15921  283 LTEKASS-ARSQANSIQSQLEIIQEQARNQNsmymrQLSDLESTVSQLRSELREAKRMyEDKIEELEKQLVLANSELTEA 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1241 EGESKELKRLVVAESEKSQKL----EERLRLLQVETASNSaRAAERSSA-------LREEVQSLREEVEKQRVVSENSRQ 1309
Cdd:pfam15921  362 RTERDQFSQESGNLDDQLQKLladlHKREKELSLEKEQNK-RLWDRDTGnsitidhLRRELDDRNMEVQRLEALLKAMKS 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1310 ELASQAER--------------AEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEK 1375
Cdd:pfam15921  441 ECQGQMERqmaaiqgkneslekVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT 520

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1376 RFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEkasyAEQLSMLKKAHGLLAeeNRGLGERAN 1455
Cdd:pfam15921  521 KLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQ----IENMTQLVGQHGRTA--GAMQVEKAQ 594

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1456 LGRQFLEVELDqarekyVQELAAVRTDAETHLAEMrqEAQSTSRELEvmTAKYEGAKVKVLEERQRFQEERQKLTAQVEQ 1535
Cdd:pfam15921  595 LEKEINDRRLE------LQEFKILKDKKDAKIREL--EARVSDLELE--KVKLVNAGSERLRAVKDIKQERDQLLNEVKT 664

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1536 LEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAfqaQRGESQQEVQRLQTQLNELQAQLSQKEQAAehykLQMEKAKT 1615
Cdd:pfam15921  665 SRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKM---QLKSAQSELEQTRNTLKSMEGSDGHAMKVA----MGMQKQIT 737

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115 1616 hydAKKQQNQKLQEQLQDLEEL----QKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQL 1690
Cdd:pfam15921  738 ---AKRGQIDALQSKIQFLEEAmtnaNKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVAL 813
PRK11281 PRK11281
mechanosensitive channel MscK;
341-581 8.98e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.98  E-value: 8.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  341 DLIEEHSKASQEWAEKQARLENELSTaLQDKKCLEEKNEILQ-------GKLSQLEDQATRLQESPAPEKGEVLgDALQL 413
Cdd:PRK11281    46 DALNKQKLLEAEDKLVQQDLEQTLAL-LDKIDRQKEETEQLKqqlaqapAKLRQAQAELEALKDDNDEETRETL-STLSL 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  414 DTLKQeaaKLATDNTQLQTRVETLecerGKQEAQLLAERSRFE----------DEKQQLASLIADLQSSVSNLS---QAK 480
Cdd:PRK11281   124 RQLES---RLAQTLDQLQNAQNDL----AEYNSQLVSLQTQPEraqaalyansQRLQQIRNLLKGGKVGGKALRpsqRVL 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  481 EELEQAS-QAQGAQLTAQLTSMTGLNATLQQRdQELASLKEQakkEQAQMLQTMQEqeqAAQGLRqqveqlsssLKLKEQ 559
Cdd:PRK11281   197 LQAEQALlNAQNDLQRKSLEGNTQLQDLLQKQ-RDYLTARIQ---RLEHQLQLLQE---AINSKR---------LTLSEK 260

                          250       260
                   ....*....|....*....|....*.
gi 2214681115  560 QLEEAAKEQEATRQDH----AQQLAI 581
Cdd:PRK11281   261 TVQEAQSQDEAARIQAnplvAQELEI 286
PRK09039 PRK09039
peptidoglycan -binding protein;
456-621 9.10e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 46.88  E-value: 9.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  456 EDEKQQLASLIADLQSSVSNLSQAKEELeqasQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQE 535
Cdd:PRK09039    52 DSALDRLNSQIAELADLLSLERQGNQDL----QDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQELDS 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  536 QEQAAQGLRQQVEQLSsslklkeQQLeeaakeqEATRqdhaQQLAIVAEAREASlrerdtarqqlETVEKEKDAKLESLQ 615
Cdd:PRK09039   128 EKQVSARALAQVELLN-------QQI-------AALR----RQLAALEAALDAS-----------EKRDRESQAKIADLG 178


                   ....*.
gi 2214681115  616 QQLQAA 621
Cdd:PRK09039   179 RRLNVA 184
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 333-637 1.00e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 47.74  E-value: 1.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  333 QQLQGAFNDLieEHSKASQEWAEKQARLENE---LSTALQDKKCLEEKN---------------EILQGKlSQLEDQATR 394
Cdd:PRK10929    48 EALQSALNWL--EERKGSLERAKQYQQVIDNfpkLSAELRQQLNNERDEprsvppnmstdaleqEILQVS-SQLLEKSRQ 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  395 LQESPapEKGEVLGDAL-QLDTLKQEAAKLATD-------------------NTQLQT-------RVETLECergkqeAQ 447
Cdd:PRK10929   125 AQQEQ--DRAREISDSLsQLPQQQTEARRQLNEierrlqtlgtpntplaqaqLTALQAesaalkaLVDELEL------AQ 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  448 LLAE------RSRFEDEKQQLASLIADLQSSVSNL-SQAKEELEQASQA------QGAQLTAQLTSMTGLNATLQQrdqe 514
Cdd:PRK10929   197 LSANnrqelaRLRSELAKKRSQQLDAYLQALRNQLnSQRQREAERALEStellaeQSGDLPKSIVAQFKINRELSQ---- 272

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  515 laslkeqAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRqdhaQQLAIVAEAREASLRERD 594
Cdd:PRK10929   273 -------ALNQQAQRMDLIASQQRQAASQTLQVRQALNTLREQSQWLGVSNALGEALR----AQVARLPEMPKPQQLDTE 341

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 2214681115  595 TARQQLETVekekdaKLESLQQQLQAANDARDNAQTSVTQAQQ 637
Cdd:PRK10929   342 MAQLRVQRL------RYEDLLNKQPQLRQIRQADGQPLTAEQN 378
mukB PRK04863
chromosome partition protein MukB;
1272-1657 1.22e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.64  E-value: 1.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1272 TASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKfFQKEQALSALQLEHTSTQA 1351
Cdd:PRK04863   277 HANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDH-LNLVQTALRQQEKIERYQA 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1352 LVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELgslrQKIVEQERAAQQL--RAEKASY 1429
Cdd:PRK04863   356 DLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQ----QTRAIQYQQAVQAleRAKQLCG 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1430 AEQLSmLKKAHGLLAE---ENRGLGERANLGRQFLEVElDQAREKYVQELAAVRTDAethlAEM-RQEAQSTSRELEVMT 1505
Cdd:PRK04863   432 LPDLT-ADNAEDWLEEfqaKEQEATEELLSLEQKLSVA-QAAHSQFEQAYQLVRKIA----GEVsRSEAWDVARELLRRL 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1506 AKYEGAKVKVLEERQRFQEERQKLTAQ---VEQLEVFQREQTKQV---EELSKKLTEHDQaskvQQQKLKAFQAQRGESQ 1579
Cdd:PRK04863   506 REQRHLAEQLQQLRMRLSELEQRLRQQqraERLLAEFCKRLGKNLddeDELEQLQEELEA----RLESLSESVSEARERR 581

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2214681115 1580 QEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQ 1657
Cdd:PRK04863   582 MALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDE 659
PRK11637 PRK11637
AmiB activator; Provisional
 448-760 1.23e-04

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 47.00  E-value: 1.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  448 LLAERSRFEDEKQQLASLIADLqssvsnlsQAKEELEQASQaqgaqltaqltsmtglnatlQQRDQELASLKEQaKKEQA 527
Cdd:PRK11637    35 LCAFSAHASDNRDQLKSIQQDI--------AAKEKSVRQQQ--------------------QQRASLLAQLKKQ-EEAIS 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  528 QMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQleeaakeqeatrqdHAQQLAIVAEAREASLRERDTARQQLeTVEKEK 607
Cdd:PRK11637    86 QASRKLRETQNTLNQLNKQIDELNASIAKLEQQ--------------QAAQERLLAAQLDAAFRQGEHTGLQL-ILSGEE 150

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  608 DAKLESLQQQLQAANDARdnaQTSVTQAQQEKAELSQKIGELhaciEASHQEQRQVqarVTELEAQLKAEQQKTTEREKV 687
Cdd:PRK11637   151 SQRGERILAYFGYLNQAR---QETIAELKQTREELAAQKAEL----EEKQSQQKTL---LYEQQAQQQKLEQARNERKKT 220

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2214681115  688 vqekaqlqeqLRALEESLKITKGSLEEEKRRAAdALKEQQCRAtEMEAESRSLMEQREREQKELEQEKAGRKG 760
Cdd:PRK11637   221 ----------LTGLESSLQKDQQQLSELRANES-RLRDSIARA-EREAKARAEREAREAARVRDKQKQAKRKG 281
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
464-904 1.39e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 46.82  E-value: 1.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  464 SLIADLQSSVSNLSQAKEELEQASQAQGAQLtAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGL 543
Cdd:COG5278     76 SFLEPYEEARAEIDELLAELRSLTADNPEQQ-ARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEI 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  544 RQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAAND 623
Cdd:COG5278    155 RARLLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALEL 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  624 ARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEE 703
Cdd:COG5278    235 LAALALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAA 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  704 SLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHEL 783
Cdd:COG5278    315 AAAAAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLA 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  784 AEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQ 863
Cdd:COG5278    395 IAAAAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAAL 474

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 2214681115  864 LHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVA 904
Cdd:COG5278    475 AALAAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEA 515
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1467-1689 1.50e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1467 QAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQ 1546
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1547 VEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQK 1626
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2214681115 1627 LQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTcrhLTAQVRSLEAQVAHADQQ 1689
Cdd:COG4942    183 LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE---LEALIARLEAEAAAAAER 242
46 PHA02562
endonuclease subunit; Provisional
 503-725 1.60e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.55  E-value: 1.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  503 GLNATLQQRDQELASLKEQAK-------------KEQAQMLQTMQEQE-QAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQ 568
Cdd:PHA02562   178 ELNQQIQTLDMKIDHIQQQIKtynknieeqrkknGENIARKQNKYDELvEEAKTIKAEIEELTDELLNLVMDIEDPSAAL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  569 EATRQDHAQQLAIVAE-AREASLRERD----TARQQLET----VEKEKDaKLESLQQQLQAANDARDNAQ---TSVTQAQ 636
Cdd:PHA02562   258 NKLNTAAAKIKSKIEQfQKVIKMYEKGgvcpTCTQQISEgpdrITKIKD-KLKELQHSLEKLDTAIDELEeimDEFNEQS 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  637 QEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKaeqQKTTEREKVVQEKaqlqeqlraleESLKITKGSLEEEK 716
Cdd:PHA02562   337 KKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFV---DNAEELAKLQDEL-----------DKIVKTKSELVKEK 402

                          250
                   ....*....|..
gi 2214681115  717 RR---AADALKE 725
Cdd:PHA02562   403 YHrgiVTDLLKD 414
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1281-1695 1.75e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.96  E-value: 1.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1281 ERSSALREEVQSLREEVEkqrvvsensrqELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEllpak 1360
Cdd:PRK02224   206 ERLNGLESELAELDEEIE-----------RYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAE----- 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1361 hlcqqlqaeQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGeLGSLRQKIVEQERAAqqLRAEKASYAEQLSMLKKAH 1440
Cdd:PRK02224   270 ---------TEREREELAEEVRDLRERLEELEEERDDLLAEAG-LDDADAEAVEARREE--LEDRDEELRDRLEECRVAA 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1441 GLLAEENRGLGERANLgrqfLEVELDQAREKyVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKV---KVLE 1517
Cdd:PRK02224   338 QAHNEEAESLREDADD----LEERAEELREE-AAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVdlgNAED 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1518 ERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLS 1597
Cdd:PRK02224   413 FLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVE 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1598 QKEQAAEHYKlQMEKAKTHYDAKKQQNQKLQEQLQD----LEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLT 1673
Cdd:PRK02224   493 EVEERLERAE-DLVEAEDRIERLEERREDLEELIAErretIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAR 571

                          410       420
                   ....*....|....*....|..
gi 2214681115 1674 AQVRSLEAQVAHADQQLRDLGK 1695
Cdd:PRK02224   572 EEVAELNSKLAELKERIESLER 593
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 608-702 1.77e-04

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 46.26  E-value: 1.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  608 DAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQV-QARVTELEAQLK-AEQQKTTERE 685
Cdd:TIGR04320  260 QAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQTaQNNLATAQAALAnAEARLAKAKE 339

                           90
                   ....*....|....*..
gi 2214681115  686 KVVQEKAQLQEQLRALE 702
Cdd:TIGR04320  340 ALANLNADLAKKQAALD 356
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 430-803 2.09e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 46.04  E-value: 2.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  430 LQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQaqgaQLTAQLTSMTGLNATLQ 509
Cdd:pfam07888   32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELR----QSREKHEELEEKYKELS 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  510 QRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKeQEATRQDHAQQLAIVAEAREAS 589
Cdd:pfam07888  108 ASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGA-QRKEEEAERKQLQAKLQQTEEE 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  590 LRERDTARQQLETVEKEKDAKLESLQqqlqaanDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTE 669
Cdd:pfam07888  187 LRSLSKEFQELRNSLAQRDTQVLQLQ-------DTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEE 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  670 LEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESrslmeqrEREQK 749
Cdd:pfam07888  260 LSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAEL-------QRLEE 332

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2214681115  750 ELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIRE 803
Cdd:pfam07888  333 RLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAE 386
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
554-908 2.26e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 45.66  E-value: 2.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  554 LKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVT 633
Cdd:COG4372     18 LRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  634 QAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREkvvQEKAQLQEQLRALEESLKITKGSLE 713
Cdd:COG4372     98 QAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAERE---EELKELEEQLESLQEELAALEQELQ 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  714 EEKRRAADALKEQQCRATEMEAEsrSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRA 793
Cdd:COG4372    175 ALSEAEAEQALDELLKEANRNAE--KEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELL 252

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  794 ESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQ 873
Cdd:COG4372    253 EEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELAL 332

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 2214681115  874 QVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKT 908
Cdd:COG4372    333 AILLAELADLLQLLLVGLLDNDVLELLSKGAEAGV 367
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 578-903 2.29e-04

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 45.83  E-value: 2.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  578 QLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASH 657
Cdd:pfam19220   31 QLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAALREAEAAKEELR 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  658 QEQRQVQARVTELEAQLKAEqqkTTEREKVVQEKAQLQEQLRALEESLKITKGSL----------EEEKRRAADALKEQQ 727
Cdd:pfam19220  111 IELRDKTAQAEALERQLAAE---TEQNRALEEENKALREEAQAAEKALQRAEGELatarerlallEQENRRLQALSEEQA 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  728 CRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEAT----ASQHRAES------EC 797
Cdd:pfam19220  188 AELAELTRRLAELETQLDATRARLRALEGQLAAEQAERERAEAQLEEAVEAHRAERASLRmkleALTARAAAteqllaEA 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  798 ERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEihsegqpgQQQSQLAQLHASLAKAIqqvQE 877
Cdd:pfam19220  268 RNQLRDRDEAIRAAERRLKEASIERDTLERRLAGLEADLERRTQQFQEMQ--------RARAELEERAEMLTKAL---AA 336

                          330       340
                   ....*....|....*....|....*.
gi 2214681115  878 KEVRAQKLVDDLSALQEKMAATNKEV 903
Cdd:pfam19220  337 KDAALERAEERIASLSDRIAELTKRF 362
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 508-677 2.36e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.92  E-value: 2.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  508 LQQRDQELASLKEQAKKEQAQmLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEARE 587
Cdd:COG1579     12 LQELDSELDRLEHRLKELPAE-LAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKE 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  588 ASLRERD-----TARQQLETVEKEKDAKLESLQQQLQAANDARDnaqtsvtqaqQEKAELSQKIGELHACIEASHQEQRQ 662
Cdd:COG1579     91 YEALQKEieslkRRISDLEDEILELMERIEELEEELAELEAELA----------ELEAELEEKKAELDEELAELEAELEE 160

                          170
                   ....*....|....*
gi 2214681115  663 VQARVTELEAQLKAE 677
Cdd:COG1579    161 LEAEREELAAKIPPE 175
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 1572-1694 2.43e-04

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 46.48  E-value: 2.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1572 QAQRGESQQEVQRLQTQLnELQAQlsQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEA-ER 1650
Cdd:PRK11448   141 ENLLHALQQEVLTLKQQL-ELQAR--EKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKAAETSQERkQK 217

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2214681115 1651 LGRELQQAGLKTKEAEQTCRHLTaqvrsleaqvahaDQQLRDLG 1694
Cdd:PRK11448   218 RKEITDQAAKRLELSEEETRILI-------------DQQLRKAG 248
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 462-837 2.61e-04

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 45.83  E-value: 2.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  462 LASLIADLQSSVSNLSQAKEELEQAsQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQ 541
Cdd:pfam19220   22 LRSLKADFSQLIEPIEAILRELPQA-KSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAALR 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  542 GLRQQVEQLSSSLKLKEQQLEEAAKeqeatrqdhaqQLAIVAEAREASLRERDTARQQLETVEK---EKDAKLESLQQQL 618
Cdd:pfam19220  101 EAEAAKEELRIELRDKTAQAEALER-----------QLAAETEQNRALEEENKALREEAQAAEKalqRAEGELATARERL 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  619 QAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQAR-VTELEAQLKAEQQKTTEREKVVQEKAQLQEQ 697
Cdd:pfam19220  170 ALLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEGQlAAEQAERERAEAQLEEAVEAHRAERASLRMK 249

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  698 LRALEESLKITKgSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETE 777
Cdd:pfam19220  250 LEALTARAAATE-QLLAEARNQLRDRDEAIRAAERRLKEASIERDTLERRLAGLEADLERRTQQFQEMQRARAELEERAE 328

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  778 ALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKT 837
Cdd:pfam19220  329 MLTKALAAKDAALERAEERIASLSDRIAELTKRFEVERAALEQANRRLKEELQRERAERA 388
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 381-756 2.67e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 45.97  E-value: 2.67e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  381 LQGKLSQLEDQATRL-----QESPAPEKGEVLGDALQLDtlKQEAAKLATDNTQLQTRVETLECERGKQEAQLLaersRF 455
Cdd:pfam10174  298 LSKKESELLALQTKLetltnQNSDCKQHIEVLKESLTAK--EQRAAILQTEVDALRLRLEEKESFLNKKTKQLQ----DL 371

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  456 EDEKQQLASLIAD--------------LQSSVSNLSQA-------KEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQE 514
Cdd:pfam10174  372 TEEKSTLAGEIRDlkdmldvkerkinvLQKKIENLQEQlrdkdkqLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERI 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  515 LASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAakeqeatrQDHAQQLAivaeareASLRERD 594
Cdd:pfam10174  452 IERLKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDL--------KEHASSLA-------SSGLKKD 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  595 TARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTsvtqaqqeKAELSQKIGELHACIEASHQEQRQVQARVTELEAQL 674
Cdd:pfam10174  517 SKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRT--------NPEINDRIRLLEQEVARYKEESGKAQAEVERLLGIL 588

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  675 K-AEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESR-----SLMEQREREQ 748
Cdd:pfam10174  589 ReVENEKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQqlqleELMGALEKTR 668


                   ....*...
gi 2214681115  749 KELEQEKA 756
Cdd:pfam10174  669 QELDATKA 676
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 513-817 2.87e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 45.66  E-value: 2.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  513 QELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKL---KEQQLEEAAKEQEATRQDHAQQLAIVAEAREAS 589
Cdd:pfam07888   48 QAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQsreKHEELEEKYKELSASSEELSEEKDALLAQRAAH 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  590 ---LRERDTARQQLETVEKEKDAKLESLQQ-------QLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQE 659
Cdd:pfam07888  128 earIRELEEDIKTLTQRVLERETELERMKErakkagaQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQ 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  660 QRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEE---EKRRAADALKEQQCRATEME-- 734
Cdd:pfam07888  208 VLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSmaaQRDRTQAELHQARLQAAQLTlq 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  735 -AESRSLM--------EQREREQKELEQEKAGRKGLEARIQQLEEAHQAET---EALRHELAEATASQHRAESECERLIR 802
Cdd:pfam07888  288 lADASLALregrarwaQERETLQQSAEADKDRIEKLSAELQRLEERLQEERmerEKLEVELGREKDCNRVQLSESRRELQ 367

                          330
                   ....*....|....*
gi 2214681115  803 EVESRQKRFEARQQE 817
Cdd:pfam07888  368 ELKASLRVAQKEKEQ 382
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1153-1357 2.95e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 2.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1153 RAEQDKALETLQGQLEEKARELghnqaasASAQRELQALRAKAQdhskaeeewkaqVARGQQEAERKSSLISSLEEEVSI 1232
Cdd:COG3206    170 REEARKALEFLEEQLPELRKEL-------EEAEAALEEFRQKNG------------LVDLSEEAKLLLQQLSELESQLAE 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1233 LNRQVLEKEGESKELKRLV---------VAESEKSQKLEERLRLLQVETASNSARAAERSS---ALREEVQSLREEVEKQ 1300
Cdd:COG3206    231 ARAELAEAEARLAALRAQLgsgpdalpeLLQSPVIQQLRAQLAELEAELAELSARYTPNHPdviALRAQIAALRAQLQQE 310

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2214681115 1301 -RVVSENSRQELASQAERAEELGQELKAWQEKFF---QKEQALSALQLEHTSTQALVSELL 1357
Cdd:COG3206    311 aQRILASLEAELEALQAREASLQAQLAQLEARLAelpELEAELRRLEREVEVARELYESLL 371
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1033-1667 2.98e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.12  E-value: 2.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1033 AALQEALAHALTEKEGTDQELAKLRgqeaaQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAgktd 1112
Cdd:TIGR00618  222 QVLEKELKHLREALQQTQQSHAYLT-----QKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKA---- 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1113 APGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAasasaQRELQALR 1192
Cdd:TIGR00618  293 APLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRD-----AHEVATSI 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1193 AKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVET 1272
Cdd:TIGR00618  368 REISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAI 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1273 ASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELgQELKAWQEKFFQKEQALSALQLEHTSTQAL 1352
Cdd:TIGR00618  448 TCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARL-LELQEEPCPLCGSCIHPNPARQDIDNPGPL 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1353 VSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQaaggLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQ 1432
Cdd:TIGR00618  527 TRRMQRGEQTYAQLETSEEDVYHQLTSERKQRAS----LKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEK 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1433 LSMLKKAhglLAEENRGLGERAN--LGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEvmtAKYEG 1510
Cdd:TIGR00618  603 LSEAEDM---LACEQHALLRKLQpeQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLP---KELLA 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1511 AKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQ-TQL 1589
Cdd:TIGR00618  677 SRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQArTVL 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1590 NEL---QAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQL---------------------------------QD 1633
Cdd:TIGR00618  757 KARteaHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLktleaeigqeipsdedilnlqcetlvqeeeqflSR 836

                          650       660       670
                   ....*....|....*....|....*....|....
gi 2214681115 1634 LEELQKENKELRSEAERLGRELQQAGLKTKEAEQ 1667
Cdd:TIGR00618  837 LEEKSATLGEITHQLLKYEECSKQLAQLTQEQAK 870
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1257-1707 3.11e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.12  E-value: 3.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1257 KSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERA--EELGQELKAWQEKFFQ 1334
Cdd:TIGR00618  195 KAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLkkQQLLKQLRARIEELRA 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1335 KEQALSALQLEHTSTQALVSELLPAKHL--CQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKI 1412
Cdd:TIGR00618  275 QEAVLEETQERINRARKAAPLAAHIKAVtqIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1413 VEQERAAQQLRAEKASYAEQLSMLKKAHGlLAEENRGLGERANLGRQFLEVE---------LDQAREKYVQELAAVRTDA 1483
Cdd:TIGR00618  355 IHIRDAHEVATSIREISCQQHTLTQHIHT-LQQQKTTLTQKLQSLCKELDILqreqatidtRTSAFRDLQGQLAHAKKQQ 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1484 ETHLAEMRQEAQSTSRELEVMTAKyegaKVKVLEERQRFQEERQKLT---------AQVEQLEVFQREQTKQVEELSKKL 1554
Cdd:TIGR00618  434 ELQQRYAELCAAAITCTAQCEKLE----KIHLQESAQSLKEREQQLQtkeqihlqeTRKKAVVLARLLELQEEPCPLCGS 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1555 TEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEqlqDL 1634
Cdd:TIGR00618  510 CIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKE---DI 586

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2214681115 1635 EELQKENKELRSEAERLGR-ELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSRE 1707
Cdd:TIGR00618  587 PNLQNITVRLQDLTEKLSEaEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERV 660
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1146-1342 3.25e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 45.82  E-value: 3.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1146 LKSERACRAEQDKA------LETLQGQLEEKARELghnqaasASAQRELQALRAKAQDHSKAeeewkaQVARGQQEAERK 1219
Cdd:PRK10929   119 LEKSRQAQQEQDRAreisdsLSQLPQQQTEARRQL-------NEIERRLQTLGTPNTPLAQA------QLTALQAESAAL 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1220 SSLISSLE-EEVSILNRQvlekegeskELKRLvvaESEKSQKLEERL--RLLQVETASNSAR------AAERSSALREEV 1290
Cdd:PRK10929   186 KALVDELElAQLSANNRQ---------ELARL---RSELAKKRSQQLdaYLQALRNQLNSQRqreaerALESTELLAEQS 253

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2214681115 1291 QSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSAL 1342
Cdd:PRK10929   254 GDLPKSIVAQFKINRELSQALNQQAQRMDLIASQQRQAASQTLQVRQALNTL 305
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
357-571 3.74e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 3.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  357 QARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQES----PAPEKGEVLGDalQLDTLKQEAAKLATDNTQLQT 432
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKnglvDLSEEAKLLLQ--QLSELESQLAEARAELAEAEA 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  433 RVETLE--CERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLS-------QAKEELEQASQAQGAQLTAQLTSMTG 503
Cdd:COG3206    241 RLAALRaqLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTpnhpdviALRAQIAALRAQLQQEAQRILASLEA 320

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2214681115  504 LNATLQQRDQELASLKEQAKKEqaqmLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAT 571
Cdd:COG3206    321 ELEALQAREASLQAQLAQLEAR----LAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALT 384
KpsE COG3524
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
445-584 3.93e-04

Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442746 [Multi-domain]  Cd Length: 370  Bit Score: 45.23  E-value: 3.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  445 EAQLLAERSRFEDEKQQLASL-----IADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLK 519
Cdd:COG3524    183 EEEVERAEERLRDAREALLAFrnrngILDPEATAEALLQLIATLEGQLAELEAELAALRSYLSPNSPQVRQLRRRIAALE 262

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2214681115  520 EQAKKEQAQMlqTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQ---LAIVAE 584
Cdd:COG3524    263 KQIAAERARL--TGASGGDSLASLLAEYERLELEREFAEKAYTSALAALEQARIEAARQqryLAVIVQ 328
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1517-1658 4.07e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.15  E-value: 4.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1517 EERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGE--SQQEVQRLQTQLNELQA 1594
Cdd:COG1579     24 HRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrNNKEYEALQKEIESLKR 103

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2214681115 1595 QLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLE-ELQKENKELRSEAERLGRELQQA 1658
Cdd:COG1579    104 RISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKaELDEELAELEAELEELEAEREEL 168
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
543-680 4.28e-04

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 44.65  E-value: 4.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  543 LRQQVEQLSSSLKLKEQQLEeAAKEQEATRQDHAQQLAIVAEAREaslrERDTARQQLETVEKEKDAKLESlQQQLQAAN 622
Cdd:COG1566     81 LQAALAQAEAQLAAAEAQLA-RLEAELGAEAEIAAAEAQLAAAQA----QLDLAQRELERYQALYKKGAVS-QQELDEAR 154

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2214681115  623 DARDNAQTSVTQAQqekAELSQKIGELhacieASHQEQRQVQARVTELEAQLKAEQQK 680
Cdd:COG1566    155 AALDAAQAQLEAAQ---AQLAQAQAGL-----REEEELAAAQAQVAQAEAALAQAELN 204
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 211-483 4.59e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.43  E-value: 4.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  211 QFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHL-ALLNEKQAASSQEPSELEELRGKNESLTVR 289
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALrEALDELRAELTLLNEEAANLRERLESLERR 832

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  290 LHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREF---ANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELST 366
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELeseLEALLNERASLEEALALLRSELEELSEELRELESKRSE 912

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  367 ALQDKKCLEEKNEILQGKLSQLEDQATRLQESpAPEKGEVLgdalqLDTLKQEAAKLATDNTQLQTRVETLECERGK--- 443
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQER-LSEEYSLT-----LEEAEALENKIEDDEEEARRRLKRLENKIKElgp 986

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 2214681115  444 ------QEAQLLAERSRFedekqqLASLIADLQSSVSNLSQAKEEL 483
Cdd:TIGR02168  987 vnlaaiEEYEELKERYDF------LTAQKEDLTEAKETLEEAIEEI 1026
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1523-1693 5.22e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.01  E-value: 5.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1523 QEERQKLTAQVEQLEVFQREQ----------TKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNEL 1592
Cdd:TIGR04523  359 SEKQRELEEKQNEIEKLKKENqsykqeiknlESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKN 438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1593 QAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQL----QDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQT 1668
Cdd:TIGR04523  439 NSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSInkikQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKK 518

                          170       180
                   ....*....|....*....|....*
gi 2214681115 1669 CRHLTAQVRSLEAQVAHADQQLRDL 1693
Cdd:TIGR04523  519 ISSLKEKIEKLESEKKEKESKISDL 543
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 466-693 5.73e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.44  E-value: 5.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  466 IADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQ 545
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  546 QVEQLSSSLKLKEQQ-LEEAAkeqeatrqDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDA 624
Cdd:COG3883     98 SGGSVSYLDVLLGSEsFSDFL--------DRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAA 169

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115  625 RDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQ 693
Cdd:COG3883    170 KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238
PRK09039 PRK09039
peptidoglycan -binding protein;
568-721 5.84e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 44.57  E-value: 5.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  568 QEATRQDHA-----QQLAIVAEAreASLRERdtARQQLEtvekekdAKLESLQQQLQAANDARDNAQTSVTQAQQEKAEL 642
Cdd:PRK09039    46 REISGKDSAldrlnSQIAELADL--LSLERQ--GNQDLQ-------DSVANLRASLSAAEAERSRLQALLAELAGAGAAA 114

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115  643 SQKIGELHACIEASHQEQRQVQARVTELEAQLkaeqqktterekvvqekAQLQEQLRALEESLKITKGSLEEEKRRAAD 721
Cdd:PRK09039   115 EGRAGELAQELDSEKQVSARALAQVELLNQQI-----------------AALRRQLAALEAALDASEKRDRESQAKIAD 176
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1537-1657 5.90e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.85  E-value: 5.90e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1537 EVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQrgesqqeVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTH 1616
Cdd:COG2433    384 ELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQ-------VERLEAEVEELEAELEEKDERIERLERELSEARSE 456

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 2214681115 1617 YDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQ 1657
Cdd:COG2433    457 ERREIRKDREISRLDREIERLERELEEERERIEELKRKLER 497
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 459-562 6.35e-04

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 44.33  E-value: 6.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  459 KQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQltsmTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQ 538
Cdd:TIGR04320  253 PNSLAALQAKLATAQADLAAAQTALNTAQAALTSAQTAY----AAAQAALATAQKELANAQAQALQTAQNNLATAQAALA 328

                           90       100
                   ....*....|....*....|....*...
gi 2214681115  539 AAQG----LRQQVEQLSSSLKLKEQQLE 562
Cdd:TIGR04320  329 NAEArlakAKEALANLNADLAKKQAALD 356
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 660-874 7.52e-04

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 44.07  E-value: 7.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  660 QRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKItkgslEEEKRRAADALKEQQCRATEMEAESRS 739
Cdd:TIGR02794   66 EQERQKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQ-----AEEKQKQAEEAKAKQAAEAKAKAEAEA 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  740 LMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRfEARQQEEA 819
Cdd:TIGR02794  141 ERKAKEEAAKQAEEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAEEAKAKAEAAKAKAAAEAAA-KAEAEAAA 219

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2214681115  820 RYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQ 874
Cdd:TIGR02794  220 AAAAEAERKADEAELGDIFGLASGSNAEKQGGARGAAAGSEVDKYAAIIQQAIQQ 274
PRK09039 PRK09039
peptidoglycan -binding protein;
504-674 8.07e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.80  E-value: 8.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  504 LNATLQQRDQELASLKEQAkkeqAQMLQTMQEQEQAAQGLRQQVEQLSSSLklkeqqleeAAKEQEatrQDHAQQLAIVA 583
Cdd:PRK09039    44 LSREISGKDSALDRLNSQI----AELADLLSLERQGNQDLQDSVANLRASL---------SAAEAE---RSRLQALLAEL 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  584 EAREASLRERDTarqqletvekEKDAKLESLQQQlqaanDARDNAQTSVTQAQQekAELSQKIGELHACIEASHQEQRQV 663
Cdd:PRK09039   108 AGAGAAAEGRAG----------ELAQELDSEKQV-----SARALAQVELLNQQI--AALRRQLAALEAALDASEKRDRES 170

                          170
                   ....*....|.
gi 2214681115  664 QARVTELEAQL 674
Cdd:PRK09039   171 QAKIADLGRRL 181
PLN02939 PLN02939
transferase, transferring glycosyl groups
 357-563 8.41e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.51  E-value: 8.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  357 QARLE--NELSTALQDKKCLEEKNEILQGKLS---------------------QLEDQATRLQESPAPEKGEVLGDALQL 413
Cdd:PLN02939   149 QARLQalEDLEKILTEKEALQGKINILEMRLSetdariklaaqekihveileeQLEKLRNELLIRGATEGLCVHSLSKEL 228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  414 DTLKQEAAKLATDNTQLQTRVETLEcERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQ 493
Cdd:PLN02939   229 DVLKEENMLLKDDIQFLKAELIEVA-ETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEKVENLQD 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  494 LTAQLTSMTGLNATLQQRDQEL--------ASLKE-QAKKEQAQMLQTMQEQEQAAQG-LRQQVEQLSSSLKLKEQQLEE 563
Cdd:PLN02939   308 LLDRATNQVEKAALVLDQNQDLrdkvdkleASLKEaNVSKFSSYKVELLQQKLKLLEErLQASDHEIHSYIQLYQESIKE 387
46 PHA02562
endonuclease subunit; Provisional
 1468-1704 8.49e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.23  E-value: 8.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1468 AREKYVQELAAVRTDAE------THLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQR 1541
Cdd:PHA02562   151 ARRKLVEDLLDISVLSEmdklnkDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAK 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1542 EQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQ---------AQLSQKEQAAEHYKLQMEK 1612
Cdd:PHA02562   231 TIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEkggvcptctQQISEGPDRITKIKDKLKE 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1613 AKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRD 1692
Cdd:PHA02562   311 LQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDK 390

                          250       260
                   ....*....|....*....|...
gi 2214681115 1693 LGK-----------FQVATDALK 1704
Cdd:PHA02562   391 IVKtkselvkekyhRGIVTDLLK 413
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 994-1213 9.12e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 9.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  994 ARLTQERGQAQADLAQEKAAKAELEMR---LQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKEL 1070
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEekaLLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1071 QQTLEQLKIQLVKKEK-EHPAGGASGEDASGPGTQSETAGK-TDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKS 1148
Cdd:COG4942    103 KEELAELLRALYRLGRqPPLALLLSPEDFLDAVRRLQYLKYlAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2214681115 1149 ERACR-------AEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQ 1213
Cdd:COG4942    183 LEEERaalealkAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGK 254
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 459-1219 9.25e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.34  E-value: 9.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  459 KQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTaqlTSMTGLNATLQQRDQELASLKEQAKKEQaqmlqtmQEQEQ 538
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLR---QSVIDLQTKLQEMQMERDAMADIRRRES-------QSQED 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  539 AAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAR-------EAS---LRERDTAR----------- 597
Cdd:pfam15921  143 LRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRsilvdfeEASgkkIYEHDSMStmhfrslgsai 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  598 ----QQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAElsQKIGELHACIEASHQEQRQVQARVTELEAQ 673
Cdd:pfam15921  223 skilRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIE--QLISEHEVEITGLTEKASSARSQANSIQSQ 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  674 LKAEQqktterEKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAEsrsLMEQRErEQKELEQ 753
Cdd:pfam15921  301 LEIIQ------EQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSE---LTEART-ERDQFSQ 370

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  754 EKAgrkGLEARIQQ-LEEAHQAETE-ALRHELAEATASQHRAESecerliREVESRQKRFEARQQEEARYGAMfqeqLMA 831
Cdd:pfam15921  371 ESG---NLDDQLQKlLADLHKREKElSLEKEQNKRLWDRDTGNS------ITIDHLRRELDDRNMEVQRLEAL----LKA 437

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  832 LKGEKTGQeVQEEAVEIHSEGQPGQQQSQL-AQLHAS---LAKAIQQVQEKEV---RAQKLVDDLSA-LQEK---MAATN 900
Cdd:pfam15921  438 MKSECQGQ-MERQMAAIQGKNESLEKVSSLtAQLESTkemLRKVVEELTAKKMtleSSERTVSDLTAsLQEKeraIEATN 516

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  901 KEVACLKTLV-LKAGE--------------QQETASLEL-------LKEPPRAANRASDQLGEQQGRPFSSTHAAVKAME 958
Cdd:pfam15921  517 AEITKLRSRVdLKLQElqhlknegdhlrnvQTECEALKLqmaekdkVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLE 596

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  959 REAEQMGGELERLRA------ALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEF 1032
Cdd:pfam15921  597 KEINDRRLELQEFKIlkdkkdAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDY 676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1033 AALQEALAHALTEKEGTDQELaklrgqeaaqRTELKELQQTLEQLKIQLVKKEkehpaggasGEDASGPGTQSETAGKTD 1112
Cdd:pfam15921  677 EVLKRNFRNKSEEMETTTNKL----------KMQLKSAQSELEQTRNTLKSME---------GSDGHAMKVAMGMQKQIT 737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1113 APGPELQALRAEISKLEqqcqqqqqqvEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRelqaLR 1192
Cdd:pfam15921  738 AKRGQIDALQSKIQFLE----------EAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERR----LK 803

                          810       820
                   ....*....|....*....|....*..
gi 2214681115 1193 AKAQDHSKAEEEWKAQVARGQQEAERK 1219
Cdd:pfam15921  804 EKVANMEVALDKASLQFAECQDIIQRQ 830
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 516-638 9.41e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 44.43  E-value: 9.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  516 ASLKEQAKKeqaqmlqtMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQlaIVAEAR-EASLRERD 594
Cdd:PRK00409   523 ASLEELERE--------LEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQ--AIKEAKkEADEIIKE 592

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2214681115  595 TARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQE 638
Cdd:PRK00409   593 LRQLQKGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEKQEE 636
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1004-1651 9.52e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.44  E-value: 9.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1004 QADLAQEKAAKAELE------MRLQNTLNEQRVEFAALQEALAHALTEKEGTDQEL-AKLRGQEAAQRTELKELQQTLEQ 1076
Cdd:pfam12128  247 QQEFNTLESAELRLShlhfgyKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKrDELNGELSAADAAVAKDRSELEA 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1077 LKIQLVKKEKEHpAGGASGEDASGPGTQSET-------AGKTDAPGPELQALRAEISKLeqqCQQQQQQVEGLTHSLKSE 1149
Cdd:pfam12128  327 LEDQHGAFLDAD-IETAAADQEQLPSWQSELenleerlKALTGKHQDVTAKYNRRRSKI---KEQNNRDIAGIKDKLAKI 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1150 RACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAK----AQDHSKAEEEWKAQVARGQQEAERKSSLISS 1225
Cdd:pfam12128  403 REARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGelklRLNQATATPELLLQLENFDERIERAREEQEA 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1226 LEEEVSILNRQVLEKEGESKELKRlvvAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKqrVVSe 1305
Cdd:pfam12128  483 ANAEVERLQSELRQARKRRDQASE---ALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGK--VIS- 556

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1306 nsrQELASQAERAEELGQELKAWQEKFFQKEQALSALQLE--HTSTQALVSELLPAKhlcqQLQAEQAAAEKRFREELEQ 1383
Cdd:pfam12128  557 ---PELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPewAASEEELRERLDKAE----EALQSAREKQAAAEEQLVQ 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1384 SKQAAGGLQAELMRAQREL-----------GELGSLRQKIVEQERAAQQLRAEK-ASYAEQLSMLKKAHGLLAEENRG-- 1449
Cdd:pfam12128  630 ANGELEKASREETFARTALknarldlrrlfDEKQSEKDKKNKALAERKDSANERlNSLEAQLKQLDKKHQAWLEEQKEqk 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1450 --LGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEaqsTSRELevmtakyegAKVKVLEER-QRFQEER 1526
Cdd:pfam12128  710 reARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETW---YKRDL---------ASLGVDPDViAKLKREI 777

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1527 QKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQAskvqqqklkaFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHY 1606
Cdd:pfam12128  778 RTLERKIERIAVRRQEVLRYFDWYQETWLQRRPR----------LATQLSNIERAISELQQQLARLIADTKLRRAKLEME 847

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 2214681115 1607 KLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERL 1651
Cdd:pfam12128  848 RKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGERL 892
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
 402-574 1.00e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 43.57  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  402 EKGEVLgdaLQLDTLKQEAAKLATDNTQLQTRvetlecergKQEAQLLAERSRFE-------DEKQQLASLIADLQSSVS 474
Cdd:pfam00529   43 KAGDVL---FQLDPTDYQAALDSAEAQLAKAQ---------AQVARLQAELDRLQaleselaISRQDYDGATAQLRAAQA 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  475 NLSQAKEELEQA-SQAQGAQLTAQLTSMTGlnATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSS 553
Cdd:pfam00529  111 AVKAAQAQLAQAqIDLARRRVLAPIGGISR--ESLVTAGALVAQAQANLLATVAQLDQIYVQITQSAAENQAEVRSELSG 188

                          170       180
                   ....*....|....*....|.
gi 2214681115  554 LklkEQQLEEAAKEQEATRQD 574
Cdd:pfam00529  189 A---QLQIAEAEAELKLAKLD 206
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 850-1120 1.03e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  850 SEGQpgQQQSQLAQlHASLAKAIQQVQEKEVRA-----------QKLVDDLSALQEKMAATNKEVACLKTLVLKAG--EQ 916
Cdd:NF012221  1538 SESS--QQADAVSK-HAKQDDAAQNALADKERAeadrqrleqekQQQLAAISGSQSQLESTDQNALETNGQAQRDAilEE 1614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  917 QETASLELLKEPPR-AANRASDQLGEQQGRPFSsTHAAVKAMEREAEQM-------GGELERLRAALIKSQGQQQEERGQ 988
Cdd:NF012221  1615 SRAVTKELTTLAQGlDALDSQATYAGESGDQWR-NPFAGGLLDRVQEQLddakkisGKQLADAKQRHVDNQQKVKDAVAK 1693

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  989 QEREVARLTQERGQAQADLAQekaAKAELEMRLQNTLNEQRVefAALQEALAHALTEKegtdqelAKLRGQEAAQRTELK 1068
Cdd:NF012221  1694 SEAGVAQGEQNQANAEQDIDD---AKADAEKRKDDALAKQNE--AQQAESDANAAAND-------AQSRGEQDASAAENK 1761

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2214681115 1069 ELQQTLEQLKIQLVKKEKEHPAgGASGEDASGPGTQSETAGKTD-APGPELQA 1120
Cdd:NF012221  1762 ANQAQADAKGAKQDESDKPNRQ-GAAGSGLSGKAYSVEGVAEPGsHINPDSPA 1813
PRK12705 PRK12705
hypothetical protein; Provisional
 614-777 1.03e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 43.93  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  614 LQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELhaCIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQ 693
Cdd:PRK12705    25 LKKRQRLAKEAERILQEAQKEAEEKLEAALLEAKEL--LLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKLDN 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  694 LQEQLRALEESLKITKGSLEEEKRRAADALKEqqcRATEMEAESRSLMEQreREQKELEQEKAgrkgleARIQQLEEAHQ 773
Cdd:PRK12705   103 LENQLEEREKALSARELELEELEKQLDNELYR---VAGLTPEQARKLLLK--LLDAELEEEKA------QRVKKIEEEAD 171


                   ....
gi 2214681115  774 AETE 777
Cdd:PRK12705   172 LEAE 175
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1516-1689 1.08e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1516 LEERQRFQEERQKLTAQVEQLevfqREQTKQVEELSKKLTEHDQASKVQQQKLKA--FQAQRGESQQEVQRLQTQLNELQ 1593
Cdd:COG4717     70 LKELKELEEELKEAEEKEEEY----AELQEELEELEEELEELEAELEELREELEKleKLLQLLPLYQELEALEAELAELP 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1594 AQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKEN-KELRSEAERLGRELQQAGLKTKEAEQTCRHL 1672
Cdd:COG4717    146 ERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAELEEELEEAQEELEEL 225

                          170
                   ....*....|....*..
gi 2214681115 1673 TAQVRSLEAQVAHADQQ 1689
Cdd:COG4717    226 EEELEQLENELEAAALE 242
mukB PRK04863
chromosome partition protein MukB;
298-564 1.17e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.18  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  298 QNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQ---GAFNDLIEEHskasqeWAEKQARLENELSTALQDKKCL 374
Cdd:PRK04863   840 RQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNrllPRLNLLADET------LADRVEEIREQLDEAEEAKRFV 913

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  375 EEKneilQGKLSQLEDQATRLQESP---APEKGEVLGDALQLDTLKQ------------------EAAKLATDNT----Q 429
Cdd:PRK04863   914 QQH----GNALAQLEPIVSVLQSDPeqfEQLKQDYQQAQQTQRDAKQqafaltevvqrrahfsyeDAAEMLAKNSdlneK 989

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  430 LQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEqasqaqgaQLTAQLTSmtGLNATLQ 509
Cdd:PRK04863   990 LRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQ--------DLGVPADS--GAEERAR 1059

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2214681115  510 QRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEA 564
Cdd:PRK04863  1060 ARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNA 1114
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 610-796 1.22e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 1.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  610 KLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKtterekvvQ 689
Cdd:COG1579     11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQ--------L 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  690 EKAQLQEQLRALEESLKitkgSLEEEKRRAADALKEqqcratemeaesrsLMEQREREQKELEQEKAGRKGLEARIQQLE 769
Cdd:COG1579     83 GNVRNNKEYEALQKEIE----SLKRRISDLEDEILE--------------LMERIEELEEELAELEAELAELEAELEEKK 144

                          170       180
                   ....*....|....*....|....*..
gi 2214681115  770 EAHQAETEALRHELAEATASQHRAESE 796
Cdd:COG1579    145 AELDEELAELEAELEELEAEREELAAK 171
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
929-1344 1.27e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  929 PRAANRASDQLGEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAALikSQGQQQEERGQQEREVARLTQERGQAQADLA 1008
Cdd:COG4717     65 KPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAEL--EELREELEKLEKLLQLLPLYQELEALEAELA 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1009 QEKAAKAELEMR------LQNTLNEQRVEFAALQEALAHALTEK--------EGTDQELAKLRGQEAAQRTELKELQQTL 1074
Cdd:COG4717    143 ELPERLEELEERleelreLEEELEELEAELAELQEELEELLEQLslateeelQDLAEELEELQQRLAELEEELEEAQEEL 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1075 EQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRA 1154
Cdd:COG4717    223 EELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGK 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1155 EQDK-----ALETLQGQ-LEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEE 1228
Cdd:COG4717    303 EAEElqalpALEELEEEeLEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVE 382

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1229 EVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETAsnsARAAERSSALREEVQSLREEVEK--QRVVSEN 1306
Cdd:COG4717    383 DEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE---EELEEELEELEEELEELEEELEElrEELAELE 459

                          410       420       430
                   ....*....|....*....|....*....|....*...
gi 2214681115 1307 SRQELASQAERAEELGQELKAWQEKFFQKEQALSALQL 1344
Cdd:COG4717    460 AELEQLEEDGELAELLQELEELKAELRELAEEWAALKL 497
PRK11281 PRK11281
mechanosensitive channel MscK;
1375-1679 1.27e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.13  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1375 KRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLgerA 1454
Cdd:PRK11281    76 DRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQL---V 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1455 NLgrqfleveldQAREKYVQelaAVRTDAETHLAEMRQEAQSTSrelevmtakyEGAKVKVLEERQRFQEERQKLTAQVE 1534
Cdd:PRK11281   153 SL----------QTQPERAQ---AALYANSQRLQQIRNLLKGGK----------VGGKALRPSQRVLLQAEQALLNAQND 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1535 QlevfqreqtkQVEELskkltehdqASKVQQQKLkaFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAaehyklQMEKAk 1614
Cdd:PRK11281   210 L----------QRKSL---------EGNTQLQDL--LQKQRDYLTARIQRLEHQLQLLQEAINSKRLT------LSEKT- 261

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2214681115 1615 thydAKKQQNQKLQEQLQDLEELQKE---NKELRS---EAERLGRELQQAGLKTKE----AEQTCRHLTAQVRSL 1679
Cdd:PRK11281   262 ----VQEAQSQDEAARIQANPLVAQEleiNLQLSQrllKATEKLNTLTQQNLRVKNwldrLTQSERNIKEQISVL 332
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 460-621 1.30e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 1.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  460 QQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQA 539
Cdd:COG1579     13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  540 AqgLRQQVEqlssSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQ 619
Cdd:COG1579     93 A--LQKEIE----SLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAERE 166


                   ..
gi 2214681115  620 AA 621
Cdd:COG1579    167 EL 168
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 669-817 1.32e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 1.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  669 ELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQRERE- 747
Cdd:COG1579     14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEa 93

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2214681115  748 -QKELEQEKAGRKGLEARIQQLE---EAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQE 817
Cdd:COG1579     94 lQKEIESLKRRISDLEDEILELMeriEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREE 167
mukB PRK04863
chromosome partition protein MukB;
1118-1693 1.50e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.79  E-value: 1.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1118 LQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKaLETLQGQLEEKARELGHNQAASASAQRELQALRAKAQD 1197
Cdd:PRK04863   309 LVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEK-IERYQADLEELEERLEEQNEVVEEADEQQEENEARAEA 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1198 HSKAEEEWKAQVARGQQ---EAERKSS----LISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQK---LEERLRL 1267
Cdd:PRK04863   388 AEEEVDELKSQLADYQQaldVQQTRAIqyqqAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEEllsLEQKLSV 467

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1268 L-----QVETASNSARAA----ERSSALREEVQSLREeVEKQRVVSENS----------RQELASQAeRAEELGQELKAW 1328
Cdd:PRK04863   468 AqaahsQFEQAYQLVRKIagevSRSEAWDVARELLRR-LREQRHLAEQLqqlrmrlselEQRLRQQQ-RAERLLAEFCKR 545

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1329 QEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGE---- 1404
Cdd:PRK04863   546 LGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGEefed 625

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1405 ---LGSLRQKIVEQERAAQQ----LRAEKASYAEQLSMLKKAHGLLAEENRGLGERAN---LGRQFLEVELDQARE---K 1471
Cdd:PRK04863   626 sqdVTEYMQQLLERERELTVerdeLAARKQALDEEIERLSQPGGSEDPRLNALAERFGgvlLSEIYDDVSLEDAPYfsaL 705

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1472 YVQELAAV----RTDAETHLAEMR-------------QEAQSTSRELEVMtakyEGAKVKVLEERQ----RFQEE----R 1526
Cdd:PRK04863   706 YGPARHAIvvpdLSDAAEQLAGLEdcpedlyliegdpDSFDDSVFSVEEL----EKAVVVKIADRQwrysRFPEVplfgR 781

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1527 QKLTAQVEQLevfqREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQ------RGESQQEVQRLQTQLNELQAQLSQKE 1600
Cdd:PRK04863   782 AAREKRIEQL----RAEREELAERYATLSFDVQKLQRLHQAFSRFIGShlavafEADPEAELRQLNRRRVELERALADHE 857

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1601 QAAEHYKLQMEKAKTHYdakkQQNQKLQEQLQDLEE--LQKENKELRSE---AERLGRELQQAGLKTKEAEQ---TCRHL 1672
Cdd:PRK04863   858 SQEQQQRSQLEQAKEGL----SALNRLLPRLNLLADetLADRVEEIREQldeAEEAKRFVQQHGNALAQLEPivsVLQSD 933

                          650       660
                   ....*....|....*....|.
gi 2214681115 1673 TAQVRSLEAQVAHADQQLRDL 1693
Cdd:PRK04863   934 PEQFEQLKQDYQQAQQTQRDA 954
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1311-1576 1.51e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1311 LASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcqqlqaeqaaaekrfREELEQSKQAAGG 1390
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL---------------------ERRIAALARRIRA 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1391 LQAELMRAQRELGELGSlrqkivEQERAAQQLRAEKASYAEQLSMLKKAHG-------LLAEENRGLGERANLGRQFLev 1463
Cdd:COG4942     74 LEQELAALEAELAELEK------EIAELRAELEAQKEELAELLRALYRLGRqpplallLSPEDFLDAVRRLQYLKYLA-- 145

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1464 eldQAREKYVQELAAVRTDaethLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQ 1543
Cdd:COG4942    146 ---PARREQAEELRADLAE----LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAEL 218

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 2214681115 1544 TKQVEELSKKLTEHDQASKVQQQKLKA--FQAQRG 1576
Cdd:COG4942    219 QQEAEELEALIARLEAEAAAAAERTPAagFAALKG 253
TOPEUc smart00435
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina ...
 1609-1692 1.56e-03

DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina virus topoisomerase, Variola virus topoisomerase, Shope fibroma virus topoisomeras


Pssm-ID: 214661 [Multi-domain]  Cd Length: 391  Bit Score: 43.11  E-value: 1.56e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  1609 QMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQ 1688
Cdd:smart00435  278 SMEKLQEKIKALKYQLKRLKKMILLFEMISDLKRKLKSKFERDNEKLDAEVKEKKKEKKKEEKKKKQIERLEERIEKLEV 357


                    ....
gi 2214681115  1689 QLRD 1692
Cdd:smart00435  358 QATD 361
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1514-1689 1.63e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.97  E-value: 1.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1514 KVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQ 1593
Cdd:COG4372      7 KVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELN 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1594 AQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEElqkENKELRSEAERLGRELQQAGLKTKEAEQTCRHLT 1673
Cdd:COG4372     87 EQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQ---QRKQLEAQIAELQSEIAEREEELKELEEQLESLQ 163

                          170
                   ....*....|....*.
gi 2214681115 1674 AQVRSLEAQVAHADQQ 1689
Cdd:COG4372    164 EELAALEQELQALSEA 179
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1509-1657 1.66e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 42.70  E-value: 1.66e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  1509 EGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQK----LKAFQAQRGESQQEVQR 1584
Cdd:smart00787  143 EGLKEGLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCdpteLDRAKEKLKKLLQEIMI 222

                            90       100       110       120       130       140       150
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2214681115  1585 LQTQLNELQAQLSQKEQAAEhyklqmekakthydAKKQQNQKLQEQLQDLEELQKENKEL-RSEAERLGRELQQ 1657
Cdd:smart00787  223 KVKKLEELEEELQELESKIE--------------DLTNKKSELNTEIAEAEKKLEQCRGFtFKEIEKLKEQLKL 282
Borrelia_P83 pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
 569-761 1.70e-03

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 43.45  E-value: 1.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  569 EATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAK---LESLQQQLQAANDARDNAQTSVTQAQQEKAELSQK 645
Cdd:pfam05262  184 EALREDNEKGVNFRRDMTDLKERESQEDAKRAQQLKEELDKKqidADKAQQKADFAQDNADKQRDEVRQKQQEAKNLPKP 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  646 igelhacieashqeqrqvqARVTEleaqlKAEQQKTTEREKVVQEKAQlQEQLRALEESLKitkgsleeEKRRAADALKe 725
Cdd:pfam05262  264 -------------------ADTSS-----PKEDKQVAENQKREIEKAQ-IEIKKNDEEALK--------AKDHKAFDLK- 309

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 2214681115  726 QQCRATEMEAESRSLMEQRERE------QKELEQEKAGRKGL 761
Cdd:pfam05262  310 QESKASEKEAEDKELEAQKKREpvaedlQKTKPQVEAQPTSL 351
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1185-1684 1.83e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.57  E-value: 1.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1185 QRELQALRAKAQDHSKAEEEWKAQVARGQQEAER----KSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKS-Q 1259
Cdd:pfam15921  123 QMERDAMADIRRRESQSQEDLRNQLQNTVHELEAakclKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASgK 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1260 KLEERLRLLQVETASNSARAAERSSALREEVQSLR-------EEVEKQRVVSENSRQELASQ-AERAEELGQE----LKA 1327
Cdd:pfam15921  203 KIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKgrifpveDQLEALKSESQNKIELLLQQhQDRIEQLISEheveITG 282

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1328 WQEKFFQKEQALSALQ--LEHTSTQALVSELLPAKHLcqqlqAEQAAAEKRFREELEQSKQAAGG----LQAELMRAQRE 1401
Cdd:pfam15921  283 LTEKASSARSQANSIQsqLEIIQEQARNQNSMYMRQL-----SDLESTVSQLRSELREAKRMYEDkieeLEKQLVLANSE 357

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1402 LGELGSLRQKIVEQ----ERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGlgerANLGRQFLEVELDQaREKYVQELA 1477
Cdd:pfam15921  358 LTEARTERDQFSQEsgnlDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTG----NSITIDHLRRELDD-RNMEVQRLE 432

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1478 AVrtdaethLAEMRQEAQStsrELEVMTAKYEGAkvkvleerqrfQEERQKLTAQVEQLEVFQREQTKQVEELS-KKLTE 1556
Cdd:pfam15921  433 AL-------LKAMKSECQG---QMERQMAAIQGK-----------NESLEKVSSLTAQLESTKEMLRKVVEELTaKKMTL 491

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1557 HDQASKVQ------QQKLKAFQAQRGESQQEVQRLQTQLNELQaQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQ 1630
Cdd:pfam15921  492 ESSERTVSdltaslQEKERAIEATNAEITKLRSRVDLKLQELQ-HLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQ 570

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2214681115 1631 LQDLEELQKENKE----LRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVA 1684
Cdd:pfam15921  571 IENMTQLVGQHGRtagaMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVS 628
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1166-1419 1.85e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 1.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1166 QLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESK 1245
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1246 ELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRvvseNSRQELASQAERAEELGQEL 1325
Cdd:COG4942    101 AQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELR----ADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1326 KAWQEKFFQKEQALSALQLEHTSTQAlvsellpakhlcqqlqaeqaaaekrfreELEQSKQAAGGLQAELMRAQREL-GE 1404
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLA----------------------------RLEKELAELAAELAELQQEAEELeAL 228

                          250
                   ....*....|....*
gi 2214681115 1405 LGSLRQKIVEQERAA 1419
Cdd:COG4942    229 IARLEAEAAAAAERT 243
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 267-491 1.87e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 1.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  267 AASSQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEH 346
Cdd:COG4942     13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  347 SKASQEWAEKQARLENELSTAL--------------QDKKCLEEKNEILQGKLSQLEDQATRLQEspapEKGEVLGDALQ 412
Cdd:COG4942     93 AELRAELEAQKEELAELLRALYrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRA----DLAELAALRAE 168

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115  413 LDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQG 491
Cdd:COG4942    169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
GBP_C pfam02841
Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ...
 669-817 1.89e-03

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.


Pssm-ID: 460721 [Multi-domain]  Cd Length: 297  Bit Score: 42.66  E-value: 1.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  669 ELEAQLKAEQQKTTEREKVVQEKAQLQEqlrALEESLKITKGSLEEEKRraadALKEQQCRATEMEAESRSLMEQREREQ 748
Cdd:pfam02841  159 KLEAKYNQVPRKGVKAEEVLQEFLQSKE---AVEEAILQTDQALTAKEK----AIEAERAKAEAAEAEQELLREKQKEEE 231

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115  749 KELEQEKagrKGLEARIQQLEEAHQAETEALRHELaEATASQHRAESecERLIRevESRQKRFEARQQE 817
Cdd:pfam02841  232 QMMEAQE---RSYQEHVKQLIEKMEAEREQLLAEQ-ERMLEHKLQEQ--EELLK--EGFKTEAESLQKE 292
MreC COG1792
Cell shape-determining protein MreC [Cell cycle control, cell division, chromosome ...
 1615-1676 1.91e-03

Cell shape-determining protein MreC [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 441397  Cd Length: 282  Bit Score: 42.56  E-value: 1.91e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2214681115 1615 THYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLgRELqqagLKTKEAEQTcRHLTAQV 1676
Cdd:COG1792     68 RSLFNLREENERLKEENAELRAELQRLEELEAENARL-REL----LDLKERLDY-KFVAAEV 123
PRK11281 PRK11281
mechanosensitive channel MscK;
612-790 1.94e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 43.36  E-value: 1.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  612 ESLQQQLQAANDARD------NAQTSVTQAQ---QEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTT 682
Cdd:PRK11281    39 ADVQAQLDALNKQKLleaedkLVQQDLEQTLallDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETL 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  683 EREKVVQEKAQLQEQLRALEE---------SLKITKGSLEEekrRAADALKEQQCRATE--------------------- 732
Cdd:PRK11281   119 STLSLRQLESRLAQTLDQLQNaqndlaeynSQLVSLQTQPE---RAQAALYANSQRLQQirnllkggkvggkalrpsqrv 195

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115  733 -MEAESRSLMEQREREQKELE-----QE--KAGRKGLEARIQQLEEAHQAETEAL---RHELAEATASQ 790
Cdd:PRK11281   196 lLQAEQALLNAQNDLQRKSLEgntqlQDllQKQRDYLTARIQRLEHQLQLLQEAInskRLTLSEKTVQE 264
Nup88 pfam10168
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ...
 1510-1648 2.03e-03

Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.


Pssm-ID: 462975 [Multi-domain]  Cd Length: 713  Bit Score: 43.11  E-value: 2.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1510 GAKVKVLEERQRFQEERQKLTAQVEQL-EVFQREQTKQvEELSKKLtehdqaskvqQQKLKAFQAQ-------RGESQQE 1581
Cdd:pfam10168  568 LQKEQQLQELQSLEEERKSLSERAEKLaEKYEEIKDKQ-EKLMRRC----------KKVLQRLNSQlpvlsdaEREMKKE 636

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2214681115 1582 VQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDA---------KKQQNQKLQEQLQDLEELQKENKELRSEA 1648
Cdd:pfam10168  637 LETINEQLKHLANAIKQAKKKMNYQRYQIAKSQSIRKKsslslsekqRKTIKEILKQLGSEIDELIKQVKDINKHV 712
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1407-1614 2.04e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.08  E-value: 2.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1407 SLRQKIVEQERAAQQLRAEKASYAEQL-------SMLKKAHGLLAEENRGLGERANLGRqfLEVELDQAREKYvQELAAV 1479
Cdd:COG3206    165 NLELRREEARKALEFLEEQLPELRKELeeaeaalEEFRQKNGLVDLSEEAKLLLQQLSE--LESQLAEARAEL-AEAEAR 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1480 RTDAETHLAEMRQEAQ--STSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEH 1557
Cdd:COG3206    242 LAALRAQLGSGPDALPelLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAE 321

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2214681115 1558 DQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAK 1614
Cdd:COG3206    322 LEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
PRK06975 PRK06975
bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed
 1566-1754 2.11e-03

bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed


Pssm-ID: 235899 [Multi-domain]  Cd Length: 656  Bit Score: 43.17  E-value: 2.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1566 QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQaaehyKLQMEKAKThydakkqqnQKLQEQLQDLeeLQKENKELR 1645
Cdd:PRK06975   357 QRQQANDAQTAELRVKTEQAQASVHQLDSQFAQLDG-----KLADAQSAQ---------QALEQQYQDL--SRNRDDWMI 420

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1646 SEAERLgreLQQAGLKTkeaeqtcrHLTAQVRSLEAQVAHADQQLRDLGKFQVAT---------DALKSrepqvKPQLDL 1716
Cdd:PRK06975   421 AEVEQM---LSSASQQL--------QLTGNVQLALIALQNADARLATSDSPQAVAvrkaiaqdiERLKA-----APSADL 484

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1717 S------------IDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASP 1754
Cdd:PRK06975   485 TglaiklddaiakIDALPLSGEALPPHATMAAAPAAAAAAAAAAAAAGEP 534
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 609-740 2.12e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 43.40  E-value: 2.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  609 AKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELhacieashqeqrqvQARVTELEAQLKAEQQKTTEREKvv 688
Cdd:PRK11448   149 QEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAEL--------------EEKQQELEAQLEQLQEKAAETSQ-- 212

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2214681115  689 QEKAQLQEQLRALEESLKITkgslEEEKRRAADalkeQQCRATEMEAESRSL 740
Cdd:PRK11448   213 ERKQKRKEITDQAAKRLELS----EEETRILID----QQLRKAGWEADSKTL 256
PRK12705 PRK12705
hypothetical protein; Provisional
 1467-1624 2.19e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 42.77  E-value: 2.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1467 QAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELevMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEvfqrEQTKQ 1546
Cdd:PRK12705    26 KKRQRLAKEAERILQEAQKEAEEKLEAALLEAKEL--LLRERNQQRQEARREREELQREEERLVQKEEQLD----ARAEK 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1547 VEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRL-QTQLNELQAQLSQ---KEQAAEHYKLQMEKAKTHYDAKKQ 1622
Cdd:PRK12705   100 LDNLENQLEEREKALSARELELEELEKQLDNELYRVAGLtPEQARKLLLKLLDaelEEEKAQRVKKIEEEADLEAERKAQ 179


                   ..
gi 2214681115 1623 QN 1624
Cdd:PRK12705   180 NI 181
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
412-717 2.21e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.58  E-value: 2.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  412 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQaQG 491
Cdd:COG4372     32 QLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE-EA 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  492 AQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLklkeQQLEEAAKEQEAT 571
Cdd:COG4372    111 EELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQEL----QALSEAEAEQALD 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  572 RQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHA 651
Cdd:COG4372    187 ELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELA 266

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2214681115  652 CIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKR 717
Cdd:COG4372    267 ILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELAL 332
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1117-1341 2.36e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1117 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1196
Cdd:COG4942     28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1197 DH----SKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVET 1272
Cdd:COG4942    108 ELlralYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEER 187

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115 1273 ASNSARAAERSSALREEVQSLREEvekqrvvsensRQELASQAERAEELGQELKAWQEKFFQKEQALSA 1341
Cdd:COG4942    188 AALEALKAERQKLLARLEKELAEL-----------AAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1261-1604 2.48e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.57  E-value: 2.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1261 LEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSEnSRQELASQAERAEELGQELKAWQEKFFQKEQALS 1340
Cdd:pfam07888   40 LQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAE-LKEELRQSREKHEELEEKYKELSASSEELSEEKD 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1341 ALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAG-------GLQAELMRAQREL----GELGSLR 1409
Cdd:pfam07888  119 ALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKeeeaerkQLQAKLQQTEEELrslsKEFQELR 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1410 QKIVEQERAAQQLRAEKASYAEQLSMLKK---AHGLLAEENRGLGERANLGRQFLEveldqAREKYVQELAAVRTDAETH 1486
Cdd:pfam07888  199 NSLAQRDTQVLQLQDTITTLTQKLTTAHRkeaENEALLEELRSLQERLNASERKVE-----GLGEELSSMAAQRDRTQAE 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1487 LAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQ-------EERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQ 1559
Cdd:pfam07888  274 LHQARLQAAQLTLQLADASLALREGRARWAQERETLQqsaeadkDRIEKLSAELQRLEERLQEERMEREKLEVELGREKD 353

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 2214681115 1560 ASKVQ----QQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAE 1604
Cdd:pfam07888  354 CNRVQlsesRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLE 402
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 632-771 2.71e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.89  E-value: 2.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  632 VTQAQQEKAELSQKIGELhacIEASHQEQRQVQARVTELEaQLKAEQQKTteREKVVQEKAQLQEQLRALeeslkitkgs 711
Cdd:PRK00409   504 IEEAKKLIGEDKEKLNEL---IASLEELERELEQKAEEAE-ALLKEAEKL--KEELEEKKEKLQEEEDKL---------- 567

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  712 LEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAgRKGLEARIQQLEEA 771
Cdd:PRK00409   568 LEEAEKEAQQAIKEAKKEADEIIKELRQLQKGGYASVKAHELIEA-RKRLNKANEKKEKK 626
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
576-703 2.77e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 42.34  E-value: 2.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  576 AQQLAIVAEAREASLRERDTARQQLETVEkekdAKLESLQQQLQAANDARDNAQT-----SVTQAQQEKAElsqkigelh 650
Cdd:COG1566     88 AEAQLAAAEAQLARLEAELGAEAEIAAAE----AQLAAAQAQLDLAQRELERYQAlykkgAVSQQELDEAR--------- 154

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2214681115  651 acieashQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEE 703
Cdd:COG1566    155 -------AALDAAQAQLEAAQAQLAQAQAGLREEEELAAAQAQVAQAEAALAQ 200
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 938-1657 2.81e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.11  E-value: 2.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  938 QLGEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERG--QAQADLAQEKAAKA 1015
Cdd:TIGR00606  287 ELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGrlQLQADRHQEHIRAR 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1016 ELEMRLQNTLNE----QRVEFAALQEALAHALTEKEGTD------QELAKLRGQEAAQ-------RTELKELQQTLEQLK 1078
Cdd:TIGR00606  367 DSLIQSLATRLEldgfERGPFSERQIKNFHTLVIERQEDeaktaaQLCADLQSKERLKqeqadeiRDEKKGLGRTIELKK 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1079 IQLVKKEKEHPAGGASGEDASGpgtQSETAGKTDApgpELQALRAEISKLEQQCQqqqqqVEGLTHSLKSERACRAEQDK 1158
Cdd:TIGR00606  447 EILEKKQEELKFVIKELQQLEG---SSDRILELDQ---ELRKAERELSKAEKNSL-----TETLKKEVKSLQNEKADLDR 515

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1159 ALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVA------RGQQEAERKSSLISSLEEEVSI 1232
Cdd:TIGR00606  516 KLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGyfpnkkQLEDWLHSKSKEINQTRDRLAK 595

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1233 LNRQVLEKEGE----SKELKRLVVAESEKSQKLEERLRLLQVEtaSNSARAAERSSALREEVQSLREEVEKQRVVSENSR 1308
Cdd:TIGR00606  596 LNKELASLEQNknhiNNELESKEEQLSSYEDKLFDVCGSQDEE--SDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLT 673

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1309 QELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAA 1388
Cdd:TIGR00606  674 DENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKL 753

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1389 GGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEkASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFleVELDQA 1468
Cdd:TIGR00606  754 QKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTD-VTIMERFQMELKDVERKIAQQAAKLQGSDLDRTV--QQVNQE 830

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1469 REKYVQELAAVRTDAEThLAEMRQEAQSTSRELEVMTAKYEGAKVKV---LEERQRFQEERQKLTAQVEQL--------- 1536
Cdd:TIGR00606  831 KQEKQHELDTVVSKIEL-NRKLIQDQQEQIQHLKSKTNELKSEKLQIgtnLQRRQQFEEQLVELSTEVQSLireikdake 909

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1537 ------EVFQREQTKQVEELSKKLTEHDQAS-KVQQQKLKAFQ-----------AQRGESQQEVQRlQTQLNELQAQLSQ 1598
Cdd:TIGR00606  910 qdspleTFLEKDQQEKEELISSKETSNKKAQdKVNDIKEKVKNihgymkdienkIQDGKDDYLKQK-ETELNTVNAQLEE 988

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115 1599 KEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQdLEELQKENKELRSEAERLGRELQQ 1657
Cdd:TIGR00606  989 CEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLT-LRKRENELKEVEEELKQHLKEMGQ 1046
HOOK pfam05622
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ...
 352-863 2.97e-03

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.


Pssm-ID: 461694 [Multi-domain]  Cd Length: 528  Bit Score: 42.37  E-value: 2.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  352 EWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDqatrLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQ 431
Cdd:pfam05622   11 ELAQRCHELDQQVSLLQEEKNSLQQENKKLQERLDQLES----GDDSGTPGGKKYLLLQKQLEQLQEENFRLETARDDYR 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  432 TRVETLECE----------------------------------RGKQEAQLLAERSRFEDE---KQQLASLIADLQSSVS 474
Cdd:pfam05622   87 IKCEELEKEvlelqhrneeltslaeeaqalkdemdilressdkVKKLEATVETYKKKLEDLgdlRRQVKLLEERNAEYMQ 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  475 NLSQAKEELEQASQAQGaQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQ---AAQGLRQQVEQLS 551
Cdd:pfam05622  167 RTLQLEEELKKANALRG-QLETYKRQVQELHGKLSEESKKADKLEFEYKKLEEKLEALQKEKERliiERDTLRETNEELR 245

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  552 -SSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT 630
Cdd:pfam05622  246 cAQLQQAELSQADALLSPSSDPGDNLAAEIMPAEIREKLIRLQHENKMLRLGQEGSYRERLTELQQLLEDANRRKNELET 325

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  631 SVTQAQQEKAELSQKIGELhacieashQEQRQVQARVTELEAQLKaeqqktterekvvQEKAQLQEQLRALEESLKITKG 710
Cdd:pfam05622  326 QNRLANQRILELQQQVEEL--------QKALQEQGSKAEDSSLLK-------------QKLEEHLEKLHEAQSELQKKKE 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  711 SLEEekrRAADALKEQQCRATEMEAESRS----LMEQREREQKELEQEKAGRKGLEARIQQleeAHQAETEALRHELAEA 786
Cdd:pfam05622  385 QIEE---LEPKQDSNLAQKIDELQEALRKkdedMKAMEERYKKYVEKAKSVIKTLDPKQNP---ASPPEIQALKNQLLEK 458

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115  787 TASQHRAESECE--RLIREVEsrqkrfearqqeearygamfqEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQ 863
Cdd:pfam05622  459 DKKIEHLERDFEksKLQREQE---------------------EKLIVTAWYNMGMALHRKAIEERLAGLSSPGQSFLAR 516
mukB PRK04863
chromosome partition protein MukB;
1377-1682 2.99e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 2.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1377 FREELEQSKQAAGGLQAELMRAQRELGELgSLRQKIVEQE----RAAQQLRAEKASYAEQLSMLKKAHGLL---AEENRG 1449
Cdd:PRK04863   291 LRRELYTSRRQLAAEQYRLVEMARELAEL-NEAESDLEQDyqaaSDHLNLVQTALRQQEKIERYQADLEELeerLEEQNE 369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1450 LGERANLGRQFLEVELDQAREKYVQ---ELAAVRT--DAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQE 1524
Cdd:PRK04863   370 VVEEADEQQEENEARAEAAEEEVDElksQLADYQQalDVQQTRAIQYQQAVQALERAKQLCGLPDLTADNAEDWLEEFQA 449

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1525 ERQKLTAQVEQLEvfQR--------EQTKQVEELSKKL---TEHDQASKVQQQKLKAFQAQRGESQQeVQRLQTQLNELQ 1593
Cdd:PRK04863   450 KEQEATEELLSLE--QKlsvaqaahSQFEQAYQLVRKIageVSRSEAWDVARELLRRLREQRHLAEQ-LQQLRMRLSELE 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1594 aQLSQKEQAAEHyklqmekakthydAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLT 1673
Cdd:PRK04863   527 -QRLRQQQRAER-------------LLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQ 592


                   ....*....
gi 2214681115 1674 AQVRSLEAQ 1682
Cdd:PRK04863   593 ARIQRLAAR 601
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 282-655 3.05e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.57  E-value: 3.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  282 KNESLTVRLHETLKQ----CQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQ 357
Cdd:pfam07888   28 RAELLQNRLEECLQEraelLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELS 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  358 aRLENELStalQDKKCLEEKNEILQGKLSQLEDQATRLQEspapekgEVLGDALQLDTLKQEAAKLATDNTQLQTRVETL 437
Cdd:pfam07888  108 -ASSEELS---EEKDALLAQRAAHEARIRELEEDIKTLTQ-------RVLERETELERMKERAKKAGAQRKEEEAERKQL 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  438 ECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQgAQLTAQLTSMTGLNATLQQRDQELAS 517
Cdd:pfam07888  177 QAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKE-AENEALLEELRSLQERLNASERKVEG 255

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  518 LKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLS-SSLKLKEQQlEEAAKEQEATRQ------DHAQQLAIVAEAREASL 590
Cdd:pfam07888  256 LGEELSSMAAQRDRTQAELHQARLQAAQLTLQLAdASLALREGR-ARWAQERETLQQsaeadkDRIEKLSAELQRLEERL 334

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115  591 RERDTARQQLET-VEKEKDAKLESL---QQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEA 655
Cdd:pfam07888  335 QEERMEREKLEVeLGREKDCNRVQLsesRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLET 403
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 615-789 3.22e-03

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 42.10  E-value: 3.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  615 QQQLQAanDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQE--QRQVQARVTELEAQLKAEQQKTTEREKVVQE-- 690
Cdd:PRK09510    67 QQQQQK--SAKRAEEQRKKKEQQQAEELQQKQAAEQERLKQLEKErlAAQEQKKQAEEAAKQAALKQKQAEEAAAKAAaa 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  691 -KAQLQEQLRALEESLKITKgslEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLE 769
Cdd:PRK09510   145 aKAKAEAEAKRAAAAAKKAA---AEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKAEAEAKKKAAAEAKKKAAA 221

                          170       180
                   ....*....|....*....|
gi 2214681115  770 EAHQAETEALRHELAEATAS 789
Cdd:PRK09510   222 EAKAAAAKAAAEAKAAAEKA 241
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 566-771 3.27e-03

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 42.10  E-value: 3.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  566 KEQEATRQDHAQQLAIVAEAREASLRERDTARQQ-LETVEKEKDAKLESLQQQLQAANDARdnaqtsvtQAQQEKAELSQ 644
Cdd:PRK09510    68 QQQQKSAKRAEEQRKKKEQQQAEELQQKQAAEQErLKQLEKERLAAQEQKKQAEEAAKQAA--------LKQKQAEEAAA 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  645 KIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKitKGSLEEEKRRAADALK 724
Cdd:PRK09510   140 KAAAAAKAKAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKK--KAEAEAKKKAAAEAKK 217

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2214681115  725 EQqcratemEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEA 771
Cdd:PRK09510   218 KA-------AAEAKAAAAKAAAEAKAAAEKAAAAKAAEKAAAAKAAA 257
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 621-823 3.37e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 3.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  621 ANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQL-KAEQQKTTEREKVVQEKAQLQEQLR 699
Cdd:COG3883     14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIdKLQAEIAEAEAEIEERREELGERAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  700 AL-EESLKITKGSLEEEKRRAADALKEQQCRATEMEAEsRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEA 778
Cdd:COG3883     94 ALyRSGGSVSYLDVLLGSESFSDFLDRLSALSKIADAD-ADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAE 172

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2214681115  779 LRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGA 823
Cdd:COG3883    173 LEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAA 217
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1550-1698 3.53e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.20  E-value: 3.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1550 LSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQE 1629
Cdd:COG4372     29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2214681115 1630 QL----QDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQV 1698
Cdd:COG4372    109 EAeelqEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEA 181
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1464-1667 3.76e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 3.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1464 ELDQAREKYVQELAAVRTDAETHLAEMRQE-----AQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEV 1538
Cdd:pfam17380  320 EAEKARQAEMDRQAAIYAEQERMAMERERElerirQEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELE 399

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1539 FQREQTKQVEELSKKLTEHDQAS---KVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQ-----LSQKEQAAEHYKLQM 1610
Cdd:pfam17380  400 AARKVKILEEERQRKIQQQKVEMeqiRAEQEEARQREVRRLEEERAREMERVRLEEQERQqqverLRQQEEERKRKKLEL 479

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2214681115 1611 EKAKTHYDAKKQQNQKLQEqlQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQ 1667
Cdd:pfam17380  480 EKEKRDRKRAEEQRRKILE--KELEERKQAMIEEERKRKLLEKEMEERQKAIYEEER 534
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 412-635 3.77e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 3.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  412 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQg 491
Cdd:COG3883     38 ELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVSYLDVLLGSESFSD- 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  492 aqLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAT 571
Cdd:COG3883    117 --FLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAA 194

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2214681115  572 RQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQA 635
Cdd:COG3883    195 EAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAA 258
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1566-1692 3.98e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.06  E-value: 3.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1566 QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQ------DLEELQK 1639
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGnvrnnkEYEALQK 96

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2214681115 1640 ENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRD 1692
Cdd:COG1579     97 EIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDE 149
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 456-564 4.03e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 42.25  E-value: 4.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  456 EDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKeqaqmlqtmQE 535
Cdd:PRK11448   141 ENLLHALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKAAE---------TS 211

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 2214681115  536 QEQAAQgLRQQVEQLSSSLKLKE--------QQLEEA 564
Cdd:PRK11448   212 QERKQK-RKEITDQAAKRLELSEeetrilidQQLRKA 247
mukB PRK04863
chromosome partition protein MukB;
1444-1714 4.08e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.64  E-value: 4.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1444 AEENRGLGERANLGRQflevELDQAREKyvqelaavRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKvkvlEERQRFQ 1523
Cdd:PRK04863   278 ANERRVHLEEALELRR----ELYTSRRQ--------LAAEQYRLVEMARELAELNEAESDLEQDYQAAS----DHLNLVQ 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1524 EERqkltAQVEQLEVFQREqtkqVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAA 1603
Cdd:PRK04863   342 TAL----RQQEKIERYQAD----LEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRA 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1604 ehykLQMEKAKTHYDAKKQQNQK---LQEQLQD-LEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSL 1679
Cdd:PRK04863   414 ----IQYQQAVQALERAKQLCGLpdlTADNAEDwLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEV 489

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 2214681115 1680 EAQVAH--ADQQLRDLGKFQvatdALKSREPQVKPQL 1714
Cdd:PRK04863   490 SRSEAWdvARELLRRLREQR----HLAEQLQQLRMRL 522
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 584-823 4.37e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 4.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  584 EAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQV 663
Cdd:COG3883     19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRS 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  664 QARVTELEAQLKAEQ-----QKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESR 738
Cdd:COG3883     99 GGSVSYLDVLLGSESfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQA 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  739 SLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEE 818
Cdd:COG3883    179 EQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAA 258


                   ....*
gi 2214681115  819 ARYGA 823
Cdd:COG3883    259 AGSAG 263
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 473-580 4.55e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 41.64  E-value: 4.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  473 VSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASlkeqAKKEQAQMLQTM-QEQEQAAQGLRQQVEQLS 551
Cdd:TIGR04320  249 IPNPPNSLAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAA----AQAALATAQKELaNAQAQALQTAQNNLATAQ 324

                           90       100
                   ....*....|....*....|....*....
gi 2214681115  552 SSLKLKEQQLEEAAKEQEATRQDHAQQLA 580
Cdd:TIGR04320  325 AALANAEARLAKAKEALANLNADLAKKQA 353
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1012-1264 4.55e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1012 AAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEhpag 1091
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE---- 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1092 gasgedasgpgtqsetagkTDAPGPELQALRAEISKL--EQQCQQQQQQVEGLTHSLKSERACRAEQdkALETLQGQLEE 1169
Cdd:COG4942     92 -------------------IAELRAELEAQKEELAELlrALYRLGRQPPLALLLSPEDFLDAVRRLQ--YLKYLAPARRE 150

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1170 KARELGHNQAASASAQRELQALRAKAQdhsKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKR 1249
Cdd:COG4942    151 QAEELRADLAELAALRAELEAERAELE---ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227

                          250
                   ....*....|....*
gi 2214681115 1250 LVVAESEKSQKLEER 1264
Cdd:COG4942    228 LIARLEAEAAAAAER 242
PRK12704 PRK12704
phosphodiesterase; Provisional
 1526-1667 4.81e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 4.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1526 RQKLTAQVEQLEVFQREQTKQVEELSK-KLTEhdqaSKVQQQKLKA-FQAQRGESQQEVQRLQTQLNELQAQLSQKEQAA 1603
Cdd:PRK12704    30 EAKIKEAEEEAKRILEEAKKEAEAIKKeALLE----AKEEIHKLRNeFEKELRERRNELQKLEKRLLQKEENLDRKLELL 105

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2214681115 1604 EHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEelQKENKELrseaERLgrelqqAGLKTKEAEQ 1667
Cdd:PRK12704   106 EKREEELEKKEKELEQKQQELEKKEEELEELI--EEQLQEL----ERI------SGLTAEEAKE 157
mukB PRK04863
chromosome partition protein MukB;
486-823 4.87e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 4.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  486 ASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQT--MQEQEQAAQGLRQQVeqlssslklkeQQLEE 563
Cdd:PRK04863   783 AREKRIEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFIGSHLAVafEADPEAELRQLNRRR-----------VELER 851

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  564 AAKEQEATRQDHAQQLaivaeareaslrerDTARQQLETVEK-EKDAKL---ESLQQQLQAANDARDNAQTSVTQAQQEK 639
Cdd:PRK04863   852 ALADHESQEQQQRSQL--------------EQAKEGLSALNRlLPRLNLladETLADRVEEIREQLDEAEEAKRFVQQHG 917

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  640 AELSQkIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKA--------QLQEQLRALEESLKITKGS 711
Cdd:PRK04863   918 NALAQ-LEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRAhfsyedaaEMLAKNSDLNEKLRQRLEQ 996

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  712 LEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQ---KELEQEKA-----GRKGLEARIQQLEEAHQAETEALRHEL 783
Cdd:PRK04863   997 AEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRqmlQELKQELQdlgvpADSGAEERARARRDELHARLSANRSRR 1076

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 2214681115  784 AEATASQHRAESECERLIREVESRQKrfEARQQEEARYGA 823
Cdd:PRK04863  1077 NQLEKQLTFCEAEMDNLTKKLRKLER--DYHEMREQVVNA 1114
PTZ00491 PTZ00491
major vault protein; Provisional
 601-756 5.76e-03

major vault protein; Provisional


Pssm-ID: 240439 [Multi-domain]  Cd Length: 850  Bit Score: 41.93  E-value: 5.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  601 ETVEKEKDAKLESLQQQLQAANDARDNAQTSvtQAQQEKAELSQkigelhaciEASHQEQRQVqarvteLEAQLKAEQQK 680
Cdd:PTZ00491   636 QSVEPVDERTRDSLQKSVQLAIEITTKSQEA--AARHQAELLEQ---------EARGRLERQK------MHDKAKAEEQR 698

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2214681115  681 TTEREkVVQEKAQLQEQLRALEESLKITKGSLEEEkrRAADALKEQQCRATEMEAESRSLMEQREREQkELEQEKA 756
Cdd:PTZ00491   699 TKLLE-LQAESAAVESSGQSRAEALAEAEARLIEA--EAEVEQAELRAKALRIEAEAELEKLRKRQEL-ELEYEQA 770
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
443-780 5.77e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.43  E-value: 5.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  443 KQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQA 522
Cdd:COG4372      3 RLGEKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEEL 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  523 KKEQAQMLQTMQEQEQAaqglRQQVEQLSSSLKLKEQQLEEAAKEQEAtRQDHAQQLAIVAEAREASLRERDTARQQLET 602
Cdd:COG4372     83 EELNEQLQAAQAELAQA----QEELESLQEEAEELQEELEELQKERQD-LEQQRKQLEAQIAELQSEIAEREEELKELEE 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  603 VEKEKDAKLESLQQQLQAANDARDNAQ--TSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQK 680
Cdd:COG4372    158 QLESLQEELAALEQELQALSEAEAEQAldELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSA 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  681 TTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKG 760
Cdd:COG4372    238 LLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDAL 317

                          330       340
                   ....*....|....*....|
gi 2214681115  761 LEARIQQLEEAHQAETEALR 780
Cdd:COG4372    318 LAALLELAKKLELALAILLA 337
PRK09039 PRK09039
peptidoglycan -binding protein;
1526-1658 6.12e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 41.10  E-value: 6.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1526 RQKLTAQVEQLEvfqrEQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQ------- 1598
Cdd:PRK09039    45 SREISGKDSALD----RLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAaegrage 120

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2214681115 1599 KEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEEL----QKENKELRSEAERLGRELQQA 1658
Cdd:PRK09039   121 LAQELDSEKQVSARALAQVELLNQQIAALRRQLAALEAAldasEKRDRESQAKIADLGRRLNVA 184
PRK01156 PRK01156
chromosome segregation protein; Provisional
 274-816 6.49e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 41.81  E-value: 6.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  274 SELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSfkvrefaNHLQQLQGAFNDLieehskASQEw 353
Cdd:PRK01156   183 SNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAM-------DDYNNLKSALNEL------SSLE- 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  354 aEKQARLENELSTALQDKKCLEEKNEilqgKLSQLEDQATRLQESPAPEKGEVLGDAL----QLDTLKQEAAKLATDNTQ 429
Cdd:PRK01156   249 -DMKNRYESEIKTAESDLSMELEKNN----YYKELEERHMKIINDPVYKNRNYINDYFkyknDIENKKQILSNIDAEINK 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  430 LQTRVETLEcERGKQEAQLLAERSRFEDEKQQLASLIA---DLQSSVSNLSQAKEELEQASQAQ---GAQLTAQLTSMTG 503
Cdd:PRK01156   324 YHAIIKKLS-VLQKDYNDYIKKKSRYDDLNNQILELEGyemDYNSYLKSIESLKKKIEEYSKNIermSAFISEILKIQEI 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  504 LNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLS---------------SSLKLKEQQLEEAAKEQ 568
Cdd:PRK01156   403 DPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNgqsvcpvcgttlgeeKSNHIINHYNEKKSRLE 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  569 EATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEkDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAEL-SQKIG 647
Cdd:PRK01156   483 EKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINE-YNKIESARADLEDIKIKINELKDKHDKYEEIKNRYkSLKLE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  648 ELhaciEASHQEQRQVQARVTELEaqLKAEQQKTTEREKVVQEkaqLQEQLRALEESLKITKGSLEEEKRRAADALKEQQ 727
Cdd:PRK01156   562 DL----DSKRTSWLNALAVISLID--IETNRSRSNEIKKQLND---LESRLQEIEIGFPDDKSYIDKSIREIENEANNLN 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  728 CRATEMEAESRsLMEQREREQKELEQEKAGRKGLEARIQQLE-EAHQAETE--ALRHELAEATASQHRAESECERLIREV 804
Cdd:PRK01156   633 NKYNEIQENKI-LIEKLRGKIDNYKKQIAEIDSIIPDLKEITsRINDIEDNlkKSRKALDDAKANRARLESTIEILRTRI 711

                          570
                   ....*....|..
gi 2214681115  805 ESRQKRFEARQQ 816
Cdd:PRK01156   712 NELSDRINDINE 723
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 682-804 8.48e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.22  E-value: 8.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  682 TEREKVVQEKAQLQEQLRALEeslkITKGSLEEEKRRAADAlkeqqcRATEMEAESRSLMEQREREQKELEQEKAGRKGL 761
Cdd:COG0542    404 MEIDSKPEELDELERRLEQLE----IEKEALKKEQDEASFE------RLAELRDELAELEEELEALKARWEAEKELIEEI 473

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 2214681115  762 EARIQQLEEAHQaETEALRHELAEATAsqhrAESECERLIREV 804
Cdd:COG0542    474 QELKEELEQRYG-KIPELEKELAELEE----ELAELAPLLREE 511
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
426-572 8.67e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 40.80  E-value: 8.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  426 DNTQLQTRVETLECERGKQEAQLLAERSRfEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQltsmtgln 505
Cdd:COG1566     77 DPTDLQAALAQAEAQLAAAEAQLARLEAE-LGAEAEIAAAEAQLAAAQAQLDLAQRELERYQALYKKGAVSQ-------- 147

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2214681115  506 atlqqrdQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQ--QVEQLSSSLKLKEQQLEEAAKEQEATR 572
Cdd:COG1566    148 -------QELDEARAALDAAQAQLEAAQAQLAQAQAGLREeeELAAAQAQVAQAEAALAQAELNLARTT 209
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 636-918 8.71e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.26  E-value: 8.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  636 QQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQE-KAQLQEQLRALEESLKITKgsLEE 714
Cdd:pfam17380  302 RQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEeRKRELERIRQEEIAMEISR--MRE 379

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  715 EKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQ----EKAGRKGLEAR---IQQLEEAHQAETEALRHELAEAT 787
Cdd:pfam17380  380 LERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQkvemEQIRAEQEEARqreVRRLEEERAREMERVRLEEQERQ 459

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  788 ASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHAS 867
Cdd:pfam17380  460 QQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAE 539

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2214681115  868 LAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQE 918
Cdd:pfam17380  540 EERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAE 590
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 588-892 9.06e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 41.17  E-value: 9.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  588 ASLRERDTArQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQV--QA 665
Cdd:pfam05667  206 PSLLERNAA-ELAAAQEWEEEWNSQGLASRLTPEEYRKRKRTKLLKRIAEQLRSAALAGTEATSGASRSAQDLAELlsSF 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  666 RVTELEAQLKAEQQKTTEREKVvqekaQLQEQLRALEESLKITKGSLEEekrraadaLKEQQcratemEAESRSLMEQRE 745
Cdd:pfam05667  285 SGSSTTDTGLTKGSRFTHTEKL-----QFTNEAPAATSSPPTKVETEEE--------LQQQR------EEELEELQEQLE 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  746 REQKELEQEKAGRKGLEARIQQLEEaHQAETEALRHELAEATASQHR-------AESECERLIREVESRQKRFE--ARQQ 816
Cdd:pfam05667  346 DLESSIQELEKEIKKLESSIKQVEE-ELEELKEQNEELEKQYKVKKKtldllpdAEENIAKLQALVDASAQRLVelAGQW 424

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2214681115  817 EEARygAMFQEQLMALKGEKTGQEVQEEaveihsegqpgQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSAL 892
Cdd:pfam05667  425 EKHR--VPLIEEYRALKEAKSNKEDESQ-----------RKLEEIKELREKIKEVAEEAKQKEELYKQLVAEYERL 487
PRK11281 PRK11281
mechanosensitive channel MscK;
1034-1343 9.15e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.05  E-value: 9.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1034 ALQEALAHALTEKEGTDQ--ELAKLRGQEAAQRTELKELQQTLEQL-KIQLVKKEKEHPAGGASGEDASgpgTQSETAGK 1110
Cdd:PRK11281    27 ARAASNGDLPTEADVQAQldALNKQKLLEAEDKLVQQDLEQTLALLdKIDRQKEETEQLKQQLAQAPAK---LRQAQAEL 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1111 TDAPGPELQALRAEISKLEqqCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEkarelghNQAASASAQRELQA 1190
Cdd:PRK11281   104 EALKDDNDEETRETLSTLS--LRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPER-------AQAALYANSQRLQQ 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1191 LRAKAQDhSKAEEEWKAQVARGQQEAErksslISSLEEEVSiLNRQVLEKEGESKELKRLVVAE-SEKSQKLEERLRLLQ 1269
Cdd:PRK11281   175 IRNLLKG-GKVGGKALRPSQRVLLQAE-----QALLNAQND-LQRKSLEGNTQLQDLLQKQRDYlTARIQRLEHQLQLLQ 247

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115 1270 veTASNSARAAErSSALREEVQSLREEVEKQR---VVSENSR-----QELASQAERAEELGQE---LKAWQEKFFQKEQA 1338
Cdd:PRK11281   248 --EAINSKRLTL-SEKTVQEAQSQDEAARIQAnplVAQELEInlqlsQRLLKATEKLNTLTQQnlrVKNWLDRLTQSERN 324


                   ....*....
gi 2214681115 1339 L----SALQ 1343
Cdd:PRK11281   325 IkeqiSVLK 333
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 597-785 9.24e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 41.19  E-value: 9.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  597 RQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEK----------AELSQKIGELHA---------CIEASH 657
Cdd:PRK10929    29 TQELEQAKAAKTPAQAEIVEALQSALNWLEERKGSLERAKQYQqvidnfpklsAELRQQLNNERDeprsvppnmSTDALE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  658 QEQRQVQARVTELEAQLKAEQQKTTE-REKVVQEKAQLQEQLRALEE------SLKITKGSLEEEKRRAADA-LKEQQCR 729
Cdd:PRK10929   109 QEILQVSSQLLEKSRQAQQEQDRAREiSDSLSQLPQQQTEARRQLNEierrlqTLGTPNTPLAQAQLTALQAeSAALKAL 188

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2214681115  730 ATEMEAESRSLMEQRE--REQKELEQEKAGRkgLEARIQ----QLEEAHQAETE-ALRH--ELAE 785
Cdd:PRK10929   189 VDELELAQLSANNRQElaRLRSELAKKRSQQ--LDAYLQalrnQLNSQRQREAErALESteLLAE 251
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
596-848 9.37e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 40.66  E-value: 9.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  596 ARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLK 675
Cdd:COG4372     11 ARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQ 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  676 AEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEK 755
Cdd:COG4372     91 AAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  756 AGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGE 835
Cdd:COG4372    171 QELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEE 250

                          250
                   ....*....|...
gi 2214681115  836 KTGQEVQEEAVEI 848
Cdd:COG4372    251 LLEEVILKEIEEL 263
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 298-549 9.98e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.09  E-value: 9.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  298 QNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQ---GAFNDLIEEHSkasqewAEKQARLENELSTALQDKKCL 374
Cdd:COG3096    839 AALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNkllPQANLLADETL------ADRLEELREELDAAQEAQAFI 912

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  375 EEKNEilqgKLSQLEDQATRLQESPAPE---KGEVLGDALQLDTLKQ------------------EAAKLATDNT----Q 429
Cdd:COG3096    913 QQHGK----ALAQLEPLVAVLQSDPEQFeqlQADYLQAKEQQRRLKQqifalsevvqrrphfsyeDAVGLLGENSdlneK 988

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2214681115  430 LQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQ--ASQAQGAQLTAQlTSMTGLNAT 507
Cdd:COG3096    989 LRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEElgVQADAEAEERAR-IRRDELHEE 1067

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 2214681115  508 LQQRDQELASLKEQ---AKKEQAQMLQTMQEQEQAAQGLRQQVEQ 549
Cdd:COG3096   1068 LSQNRSRRSQLEKQltrCEAEMDSLQKRLRKAERDYKQEREQVVQ 1112
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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