|
Name |
Accession |
Description |
Interval |
E-value |
| CCDC144C |
pfam14915 |
CCDC144C protein coiled-coil region; This family includes the human protein CCDC144C and the ... |
1048-1351 |
3.87e-130 |
|
CCDC144C protein coiled-coil region; This family includes the human protein CCDC144C and the ankyrin repeat domain-containing protein 26-like 1 found in eukaryotes. Its function remains unknown, however, it is known to contain a coiled-coil domain which corresponds to this region. The ankyrin repeat which features in this protein is a common amino acid motif.
Pssm-ID: 464371 [Multi-domain] Cd Length: 304 Bit Score: 409.76 E-value: 3.87e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1048 NSNLQEEMNVLKLELDHVRSQNQQEESKYMDENENLKEKIADLRRDLKMNEETLTQTVIQYNSQLHALKTENTMLCSKLE 1127
Cdd:pfam14915 1 NCMLQDEIAMLRLEIDTIKNQNQEKEKKYLEDIEILKEKNDDLQKTLKLNEETLTKTVFQYNGQLNVLKAENTMLNSKLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1128 HEKQGKDRLETELESIRSRLTSTLQEVERNQALKIEVERTLQRERDEWLRSQDKLNHELSTIRENNNNLSQQLIRAETKS 1207
Cdd:pfam14915 81 NEKQNKERLETEVESYRSRLAAAIQDHEQSQTSKRDLELAFQRERDEWLRLQDKMNFDVSNLRDENEILSQQLSKAESKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1208 NSLENELRQTNTSLQDKVILSESTQRELTHTCGRIKELEHTLQLEKDKICKSTVKQESLQEKLAQIQSENMLLRQQIEDV 1287
Cdd:pfam14915 161 NSLENELHRTRDALREKTLLLESVQRDLSQAQCQKKELEHMYQNEQDKVNKYIGKQESLEERLAQLQSENMLLRQQLEDA 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1774923325 1288 NNKGIIKDKTVSDVQDKFTEIIAKIRADAERQVQIIEERNKDLIIKYNETREQLYRLETEKVER 1351
Cdd:pfam14915 241 QNKADAKEKTVIDIQDQFQDIVKKLQAESEKQVLLLEERNKELINECNHLKERLYQYEKEKAER 304
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
33-259 |
2.92e-49 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 177.84 E-value: 2.92e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 33 KDKDLSKLHRAASAGDVGKIKQLIKKQ-DINQLDKENRTPLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQC 111
Cdd:COG0666 51 DALGALLLLAAALAGDLLVALLLLAAGaDINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYN 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 112 QQESCATVLLEHNADPNLVDINGNAALHLAALIPSVSIAKQLLEHGANINAFNKEGCTPLILAVTENNEEMVEFLLKEGA 191
Cdd:COG0666 131 GNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGA 210
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1774923325 192 DINACDRGGRTSLMISSNNGQNNLVRILLQNEADINIKDEKSWTADDYGVMNGHHACSHLIIEHGSKK 259
Cdd:COG0666 211 DVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLL 278
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
32-259 |
2.94e-45 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 166.28 E-value: 2.94e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 32 LKDKDLSKLHRAASAGDVGKIKQLIKKQDINQLDKENRTPLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQC 111
Cdd:COG0666 18 LLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 112 QQESCATVLLEHNADPNLVDINGNAALHLAALIPSVSIAKQLLEHGANINAFNKEGCTPLILAVTENNEEMVEFLLKEGA 191
Cdd:COG0666 98 GDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGA 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1774923325 192 DINACDRGGRTSLMISSNNGQNNLVRILLQNEADINIKDEKSWTADDYGVMNGHHACSHLIIEHGSKK 259
Cdd:COG0666 178 DVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADL 245
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
40-237 |
1.13e-43 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 161.66 E-value: 1.13e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 40 LHRAASAGDVGKIKQLIKKQ-DINQLDKENRTPLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQESCAT 118
Cdd:COG0666 91 LHAAARNGDLEIVKLLLEAGaDVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVK 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 119 VLLEHNADPNLVDINGNAALHLAALIPSVSIAKQLLEHGANINAFNKEGCTPLILAVTENNEEMVEFLLKEGADINACDR 198
Cdd:COG0666 171 LLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDK 250
|
170 180 190
....*....|....*....|....*....|....*....
gi 1774923325 199 GGRTSLMISSNNGQNNLVRILLQNEADINIKDEKSWTAD 237
Cdd:COG0666 251 DGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
52-256 |
3.10e-36 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 140.09 E-value: 3.10e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 52 IKQLIKKQDINQLDKENRTPLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQESCATVLLEHNADPNLVD 131
Cdd:COG0666 5 LLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 132 INGNAALHLAALIPSVSIAKQLLEHGANINAFNKEGCTPLILAVTENNEEMVEFLLKEGADINACDRGGRTSLMISSNNG 211
Cdd:COG0666 85 DGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANG 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1774923325 212 QNNLVRILLQNEADINIKDEKSWTADDYGVMNGHHACSHLIIEHG 256
Cdd:COG0666 165 NLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAG 209
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
81-256 |
2.74e-26 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 111.20 E-value: 2.74e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 81 LDTVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQESCATVLLEHNADPNLVDINGNAALHLAALIPSVSIAKQLLEHGANI 160
Cdd:COG0666 1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 161 NAFNKEGCTPLILAVTENNEEMVEFLLKEGADINACDRGGRTSLMISSNNGQNNLVRILLQNEADINIKDEKSWTADDYG 240
Cdd:COG0666 81 NAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLA 160
|
170
....*....|....*.
gi 1774923325 241 VMNGHHACSHLIIEHG 256
Cdd:COG0666 161 AANGNLEIVKLLLEAG 176
|
|
| DUF3496 |
pfam12001 |
Domain of unknown function (DUF3496); This presumed domain is functionally uncharacterized. ... |
1765-1885 |
2.44e-24 |
|
Domain of unknown function (DUF3496); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is about 110 amino acids in length.
Pssm-ID: 463425 [Multi-domain] Cd Length: 109 Bit Score: 99.35 E-value: 2.44e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1765 RNQMEHRIQELESDLGKIKNAQQEnmlqreSTQTELERFKELYNEELKNRNSLALKLERSNERLADANAKLLNERQRTKS 1844
Cdd:pfam12001 1 RSQMELRIKDLESELSKMKTSQED------SNKIELEKYKQLYLEELKVRKSLSNKLNKTNERLAEVSTKLLVEKQQNRS 74
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1774923325 1845 LIAssimngSLATSPVVDASSFGNFSNSgFRLGGSFLSSTA 1885
Cdd:pfam12001 75 LLS------TLTTRPVLESPCVGNLNNS-LVLNRNFIPREN 108
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
138-230 |
9.81e-22 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 91.33 E-value: 9.81e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 138 LHLAALIPSVSIAKQLLEHGANINAFNKEGCTPLILAVTENNEEMVEFLLKEgADINACDRgGRTSLMISSNNGQNNLVR 217
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLEIVK 78
|
90
....*....|...
gi 1774923325 218 ILLQNEADINIKD 230
Cdd:pfam12796 79 LLLEKGADINVKD 91
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
40-231 |
1.26e-21 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 100.12 E-value: 1.26e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 40 LHRAASAGDVGKIKQLIKKQ-DINQLDKENRTPLHIAC-----ANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQ 113
Cdd:PHA03100 39 LYLAKEARNIDVVKILLDNGaDINSSTKNNSTPLHYLSnikynLTDVKEIVKLLLEYGANVNAPDNNGITPLLYAISKKS 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 114 ESCATV--LLEHNADPNLVDINGNAALHLAA--LIPSVSIAKQLLEHGANINAFNK----------------EGCTPLIL 173
Cdd:PHA03100 119 NSYSIVeyLLDNGANVNIKNSDGENLLHLYLesNKIDLKILKLLIDKGVDINAKNRvnyllsygvpinikdvYGFTPLHY 198
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1774923325 174 AVTENNEEMVEFLLKEGADINACDRGGRTSLMISSNNGQNNLVRILLQNEADINIKDE 231
Cdd:PHA03100 199 AVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNGPSIKTIIE 256
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
883-1681 |
4.31e-21 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 101.29 E-value: 4.31e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 883 KKMENEKKDLQQIAEKNRELKSMLDHQKVESESdlnSLRFTLKQEEEKRKNAEMLYGK----------SQEQLRRKEDQC 952
Cdd:TIGR02168 179 RKLERTRENLDRLEDILNELERQLKSLERQAEK---AERYKELKAELRELELALLVLRleelreeleeLQEELKEAEEEL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 953 CQEMEAKQLLELTIRNLELEMRSMqntvrqvEEERNEVQRLLsheHNARIAQEDILNNIRRKSEEIENEKmwTKNAEVHG 1032
Cdd:TIGR02168 256 EELTAELQELEEKLEELRLEVSEL-------EEEIEELQKEL---YALANEISRLEQQKQILRERLANLE--RQLEELEA 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1033 QLSKIDEREKDLILQNSNLQEEMNVLKLELDHVRSQNQQEESKYmdenENLKEKIADLRRDLkmneETLTQTVIQYNSQL 1112
Cdd:TIGR02168 324 QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL----EELESRLEELEEQL----ETLRSKVAQLELQI 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1113 HALKTENTMLCSKLEHEKQGKDRLETELESIRSRLTST-LQEVERNQALKIEVERTLQRERDEWLRSQDKLNHELSTIRE 1191
Cdd:TIGR02168 396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1192 NNNNLSQQLIRAETKSNSLENeLRQTNTSLQDKVILSESTQRELTHTCGRIKELEHTLqlEKDKICKSTVKQESLQ---- 1267
Cdd:TIGR02168 476 ALDAAERELAQLQARLDSLER-LQENLEGFSEGVKALLKNQSGLSGILGVLSELISVD--EGYEAAIEAALGGRLQavvv 552
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1268 ----------------------------EKLAQIQSENMLLRQQIEDVNNKGIIKDKTVSDVQDKFTEIIAKIR-----A 1314
Cdd:TIGR02168 553 enlnaakkaiaflkqnelgrvtflpldsIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLvvddlD 632
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1315 DAERQVQIIEER-----------NKDLIIKYNETREQLYRLEtekveRESTLRQLQQELADALKKLSMSEASLEVITRYR 1383
Cdd:TIGR02168 633 NALELAKKLRPGyrivtldgdlvRPGGVITGGSAKTNSSILE-----RRREIEELEEKIEELEEKIAELEKALAELRKEL 707
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1384 NDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEYSSAAAGDENAIKELEGHVQKL 1463
Cdd:TIGR02168 708 EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL 787
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1464 EIENAKFEATAKQQAGQIDILQKELRETLSIRHKLEELIASLQSSKmgleeklnhqvhkqTALSQSAQDSHNLWEEELKS 1543
Cdd:TIGR02168 788 EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI--------------AATERRLEDLEEQIEELSED 853
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1544 RSRLGIRLAELEHEKAEFADQVESEKKKVKKLIEHKRSMEARFDQEIKRNAELQRDISglkKLLKTAKKKIKELESVGTQ 1623
Cdd:TIGR02168 854 IESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS---ELRRELEELREKLAQLELR 930
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*....
gi 1774923325 1624 QStqdgfksthfEKEIDIMKLKEKINEL-SFRLENESSNYKQLEAANRDLQQQLSSMKM 1681
Cdd:TIGR02168 931 LE----------GLEVRIDNLQERLSEEySLTLEEAEALENKIEDDEEEARRRLKRLEN 979
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
40-131 |
5.09e-20 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 86.32 E-value: 5.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 40 LHRAASAGDVGKIKQLIKK-QDINQLDKENRTPLHIACANGQLDTVKVLLEHKsKLNLCDNdNRSPLLKAIQCQQESCAT 118
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENgADANLQDKNGRTALHLAAKNGHLEIVKLLLEHA-DVNLKDN-GRTALHYAARSGHLEIVK 78
|
90
....*....|...
gi 1774923325 119 VLLEHNADPNLVD 131
Cdd:pfam12796 79 LLLEKGADINVKD 91
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
853-1718 |
8.61e-20 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 97.05 E-value: 8.61e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 853 NLLKFQNIIHEYERTIQRengrYKLLASKVKKMENEKKDLQQIAeknrelKSMLDHQKVESESDLNSLRFTLKQEEEKRK 932
Cdd:TIGR02168 187 NLDRLEDILNELERQLKS----LERQAEKAERYKELKAELRELE------LALLVLRLEELREELEELQEELKEAEEELE 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 933 NAEMLYGKSQEQLRRKEDQCcQEMEAKQ------LLELT--IRNLELEMRSMQNTVRQVEEERNEVQRLLSHEHNARIAQ 1004
Cdd:TIGR02168 257 ELTAELQELEEKLEELRLEV-SELEEEIeelqkeLYALAneISRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1005 EDILNNIRRKSEEIENE------KMWTKNAEVHGQLSKIDEREKDLILQNSN---LQEEMNVLKLELDHVRSQNQQEEsk 1075
Cdd:TIGR02168 336 AEELAELEEKLEELKEElesleaELEELEAELEELESRLEELEEQLETLRSKvaqLELQIASLNNEIERLEARLERLE-- 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1076 ymDENENLKEKIADLRRDLKMNEETLTQTviqynsQLHALKTENTMLCSKLEHEKQGKDRLETELESIRSRLTSTLQEVE 1155
Cdd:TIGR02168 414 --DRRERLQQEIEELLKKLEEAELKELQA------ELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1156 RNQALKIEVERTLQRERD------EWLRSQDKLNHELSTIrennnnlsQQLIRAETK-SNSLENELRQtntSLQDKVILS 1228
Cdd:TIGR02168 486 QLQARLDSLERLQENLEGfsegvkALLKNQSGLSGILGVL--------SELISVDEGyEAAIEAALGG---RLQAVVVEN 554
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1229 ESTQR-----------------ELTHTCGRIKELEHTLQLEKDKICKSTVKQ----------------------ESLQEK 1269
Cdd:TIGR02168 555 LNAAKkaiaflkqnelgrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDlvkfdpklrkalsyllggvlvvDDLDNA 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1270 LAQ---IQSENMLLRQQIEDVNNKGII---KDKTVSDVQDKFTEIiAKIRAdaerQVQIIEERNKDLIIKYNETREQLYR 1343
Cdd:TIGR02168 635 LELakkLRPGYRIVTLDGDLVRPGGVItggSAKTNSSILERRREI-EELEE----KIEELEEKIAELEKALAELRKELEE 709
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1344 LETEKVERESTLRQLQQELADALKKLSMSEASLEVITRYRNDIEGEkqilqkevekfrikVQDLEEQCNQAERLHHQLKN 1423
Cdd:TIGR02168 710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE--------------LTELEAEIEELEERLEEAEE 775
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1424 LLEDKEREVMAVSQKVQEYSSAAAGDENAIKELEGHVQKLEIENAKFEATAKQQAGQIDILQKELRETLSIRHKLEELIA 1503
Cdd:TIGR02168 776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIE 855
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1504 SLQSSKMGLEEKLNhQVHKQTALSQSAQDSHNLWEEELKSR-SRLGIRLAELEHEKAEFADQVESEKKKVKKLIEHKRSM 1582
Cdd:TIGR02168 856 SLAAEIEELEELIE-ELESELEALLNERASLEEALALLRSElEELSEELRELESKRSELRRELEELREKLAQLELRLEGL 934
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1583 EARFDQEIKRNAELQRDisglkkllktakkkikELESVGTQQSTQDGFKSthfEKEIDIMKLKEKINEL---SFRLENEs 1659
Cdd:TIGR02168 935 EVRIDNLQERLSEEYSL----------------TLEEAEALENKIEDDEE---EARRRLKRLENKIKELgpvNLAAIEE- 994
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*....
gi 1774923325 1660 snYKQLEAANRDLQQQLSSMKmfhKSQEHLEKGKRQLEDEVANLKRQIeINKVDQSLIE 1718
Cdd:TIGR02168 995 --YEELKERYDFLTAQKEDLT---EAKETLEEAIEEIDREARERFKDT-FDQVNENFQR 1047
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1070-1842 |
6.13e-19 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 94.35 E-value: 6.13e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1070 QQEESKYMDENENLkEKIADLRRDLKMNEETLT---QTVIQY--------NSQLHALKTENTMLCSKLEHEKQGKDRLET 1138
Cdd:TIGR02168 175 KETERKLERTRENL-DRLEDILNELERQLKSLErqaEKAERYkelkaelrELELALLVLRLEELREELEELQEELKEAEE 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1139 ELESIRSRLTSTLQEVERNQALKIEVERTLQRERDEWLRS---QDKLNHELSTIRENNNNLSQQLIRAETKSNSLENELR 1215
Cdd:TIGR02168 254 ELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALaneISRLEQQKQILRERLANLERQLEELEAQLEELESKLD 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1216 QTNTSLQDKVILSESTQRELTHTCGRIKELEHTLQLEKDKIckstvkqESLQEKLAQIQSENMLLRQQIEDVNNKGIIKD 1295
Cdd:TIGR02168 334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL-------EELEEQLETLRSKVAQLELQIASLNNEIERLE 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1296 KTVSDVQDKfteiiakiradAERQVQIIEERNKDLiikynetreqlyrLETEKVERESTLRQLQQELADALKKLSMSEAS 1375
Cdd:TIGR02168 407 ARLERLEDR-----------RERLQQEIEELLKKL-------------EEAELKELQAELEELEEELEELQEELERLEEA 462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1376 LEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQkVQEYSSAAAGDENAIKE 1455
Cdd:TIGR02168 463 LEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV-LSELISVDEGYEAAIEA 541
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1456 -LEGHVQKLEIENAK-----FEATAKQQAGQIDIL----------QKELRETLSIRHKLEELIASLQSSKMGLEEKLNH- 1518
Cdd:TIGR02168 542 aLGGRLQAVVVENLNaakkaIAFLKQNELGRVTFLpldsikgteiQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYl 621
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1519 --QVHKQTALSQSAQDSHNLWEEEL---------------------KSRSRLG--IRLAELEHEKAEFADQVESEKKKVK 1573
Cdd:TIGR02168 622 lgGVLVVDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsakTNSSILErrREIEELEEKIEELEEKIAELEKALA 701
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1574 KLIEHKRSMEARFDQEIKRNAELQRDISGLKKLLKTAKKKIKELESVGTQQSTQDGfksthfEKEIDIMKLKEKINELSF 1653
Cdd:TIGR02168 702 ELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT------ELEAEIEELEERLEEAEE 775
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1654 RLENESSNYKQLEAanrDLQQQLSSMKMFHKSQEHLEKGKRQLEDEVANLKRQIEINKVDQSLIEKHKREIEERGRlELK 1733
Cdd:TIGR02168 776 ELAEAEAEIEELEA---QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE-ELS 851
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1734 QKLEEVNLFLQSQAASQETLEQIRAANDAsVRNQMEHRIQELESDLGKiKNAQQENMlqrESTQTELERFKELYNEELkn 1813
Cdd:TIGR02168 852 EDIESLAAEIEELEELIEELESELEALLN-ERASLEEALALLRSELEE-LSEELREL---ESKRSELRRELEELREKL-- 924
|
810 820
....*....|....*....|....*....
gi 1774923325 1814 rNSLALKLERSNERLADANAKLLNERQRT 1842
Cdd:TIGR02168 925 -AQLELRLEGLEVRIDNLQERLSEEYSLT 952
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
72-164 |
2.29e-18 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 81.70 E-value: 2.29e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 72 LHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQESCATVLLEHnADPNLVDiNGNAALHLAALIPSVSIAK 151
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKD-NGRTALHYAARSGHLEIVK 78
|
90
....*....|...
gi 1774923325 152 QLLEHGANINAFN 164
Cdd:pfam12796 79 LLLEKGADINVKD 91
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
48-211 |
2.41e-18 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 90.47 E-value: 2.41e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 48 DVGKIKQLIKKQ-DINQLDKENRTPLHI--ACANGQLDTVKVLLEHKSKLNLCDNDNRSPLlkAIQCQ----QESCATVL 120
Cdd:PHA03095 131 NPKVIRLLLRKGaDVNALDLYGMTPLAVllKSRNANVELLRLLIDAGADVYAVDDRFRSLL--HHHLQsfkpRARIVREL 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 121 LEHNADPNLVDINGNAALHLAALIPSV--SIAKQLLEHGANINAFNKEGCTPLILAVTENNEEMVEFLLKEGADINACDR 198
Cdd:PHA03095 209 IRAGCDPAATDMLGNTPLHSMATGSSCkrSLVLPLLIAGISINARNRYGQTPLHYAAVFNNPRACRRLIALGADINAVSS 288
|
170
....*....|....*
gi 1774923325 199 GGRT--SLMISSNNG 211
Cdd:PHA03095 289 DGNTplSLMVRNNNG 303
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1125-1741 |
1.96e-17 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 89.23 E-value: 1.96e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1125 KLEHEKQGKDRLETELESIRSRLTStLQEvERNQALK-IEVERTLQ-RERDEWLRSQDKLNHELSTIRENNNNLSQQLIR 1202
Cdd:COG1196 180 KLEATEENLERLEDILGELERQLEP-LER-QAEKAERyRELKEELKeLEAELLLLKLRELEAELEELEAELEELEAELEE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1203 AETKSNSLENELRQTNTSLQDKVILSESTQRELTHTCGRIKELEHTLQLEKDKICKSTVKQESLQEKLAQIQSENMLLRQ 1282
Cdd:COG1196 258 LEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1283 QIEDVNNKGIIKDKTVSDVQDKFTEIIAKIRADAERQVQIIEERnkdliikyNETREQLYRLETEKVERESTLRQLQQEL 1362
Cdd:COG1196 338 ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL--------EELAEELLEALRAAAELAAQLEELEEAE 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1363 ADALKKLSMSEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEY 1442
Cdd:COG1196 410 EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1443 SSAAAGDENAIKELEGHVQKLEIENAKFEATAKQQAGQIDI-----LQKELRETLSIRHK---------LEELIASLQSS 1508
Cdd:COG1196 490 AARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaaYEAALEAALAAALQnivveddevAAAAIEYLKAA 569
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1509 KMGLEEKLNHQVHKQTALSQSAQdshnlwEEELKSRSRLGIRLAELEHEKAEFADQVESEKKKVKKLIEHKRSMEARFDQ 1588
Cdd:COG1196 570 KAGRATFLPLDKIRARAALAAAL------ARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLA 643
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1589 EIKRNAELQRDISGLKKLLKTAKKKIKELESVGTQQStqdgfksthfEKEIDIMKLKEKINELSFRLENESSNYKQLEAA 1668
Cdd:COG1196 644 GRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE----------LEELAERLAEEELELEEALLAEEEEERELAEAE 713
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1774923325 1669 NRDLQQQLSSMKMFHKSQEHLEKGKRQLEDEVANLKRQIEINKVDQSLIEKHKREIEE-RGRLElkqKLEEVNL 1741
Cdd:COG1196 714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERlEREIE---ALGPVNL 784
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
40-229 |
2.88e-17 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 87.24 E-value: 2.88e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 40 LHRAASAGDVGKIKQLIKK-QDINQLDKENRTPLHIACANGQLDTVKVLLEHKSKLNL----------CDNDN----RSP 104
Cdd:PHA02878 41 LHQAVEARNLDVVKSLLTRgHNVNQPDHRDLTPLHIICKEPNKLGMKEMIRSINKCSVfytlvaikdaFNNRNveifKII 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 105 LLKAIQCQQES-----------------CATVLLEHNADPNLVDIN-GNAALHLAALIPSVSIAKQLLEHGANINAFNKE 166
Cdd:PHA02878 121 LTNRYKNIQTIdlvyidkkskddiieaeITKLLLSYGADINMKDRHkGNTALHYATENKDQRLTELLLSYGANVNIPDKT 200
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1774923325 167 GCTPLILAVTENNEEMVEFLLKEGADINACDRGGRTSLMISSNNGQN-NLVRILLQNEADINIK 229
Cdd:PHA02878 201 NNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVGYCKDyDILKLLLEHGVDVNAK 264
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
60-232 |
3.47e-17 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 86.56 E-value: 3.47e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 60 DINQLDKENRTPLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQESCATVLLEHNADPNLVDINGNAALH 139
Cdd:PHA02874 116 DVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLH 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 140 LAALIPSVSIAKQLLEHGANINAFNKEGCTPLILAVTeNNEEMVEFLLKEgADINACDRGGRTSLMISSNNG-QNNLVRI 218
Cdd:PHA02874 196 NAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAII-HNRSAIELLINN-ASINDQDIDGSTPLHHAINPPcDIDIIDI 273
|
170
....*....|....
gi 1774923325 219 LLQNEADINIKDEK 232
Cdd:PHA02874 274 LLYHKADISIKDNK 287
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
38-194 |
1.13e-16 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 84.66 E-value: 1.13e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 38 SKLHRAASAGDVGKIKQLIKKQDI--NQLDKENRTPLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQES 115
Cdd:PHA02875 70 SELHDAVEEGDVKAVEELLDLGKFadDVFYKDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIK 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 116 CATVLLEHNADPNLVDINGNAALHLAALIPSVSIAKQLLEHGANINAFNKEGCTPLILAVTENNE-EMVEFLLKEGADIN 194
Cdd:PHA02875 150 GIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNGCVAALCYAIENNKiDIVRLFIKRGADCN 229
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
52-248 |
1.18e-16 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 85.08 E-value: 1.18e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 52 IKQLIKK-QDINQLDKENRTPLHIACANGQLD--TVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQESCATV--LLEHNAD 126
Cdd:PHA03095 100 IKLLIKAgADVNAKDKVGRTPLHVYLSGFNINpkVIRLLLRKGADVNALDLYGMTPLAVLLKSRNANVELLrlLIDAGAD 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 127 PNLVDINGNAALHLAALI--PSVSIAKQLLEHGANINAFNKEGCTPLILAVTENNEE--MVEFLLKEGADINACDRGGRT 202
Cdd:PHA03095 180 VYAVDDRFRSLLHHHLQSfkPRARIVRELIRAGCDPAATDMLGNTPLHSMATGSSCKrsLVLPLLIAGISINARNRYGQT 259
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1774923325 203 SLMISSNNGQNNLVRILLQNEADINIKDEKSWTADDYGVMNGHHAC 248
Cdd:PHA03095 260 PLHYAAVFNNPRACRRLIALGADINAVSSDGNTPLSLMVRNNNGRA 305
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
52-243 |
1.31e-16 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 84.72 E-value: 1.31e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 52 IKQLIKKQDINQ-LDKENRTPLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPL-----LKAIQCQQESCATVLLEHNA 125
Cdd:PHA03100 18 IKYIIMEDDLNDySYKKPVLPLYLAKEARNIDVVKILLDNGADINSSTKNNSTPLhylsnIKYNLTDVKEIVKLLLEYGA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 126 DPNLVDINGNAALHLAA--LIPSVSIAKQLLEHGANINAFNKEGCTPLILAVT--ENNEEMVEFLLKEGADINACDRggr 201
Cdd:PHA03100 98 NVNAPDNNGITPLLYAIskKSNSYSIVEYLLDNGANVNIKNSDGENLLHLYLEsnKIDLKILKLLIDKGVDINAKNR--- 174
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1774923325 202 tslmissnngqnnlVRILLQNEADINIKDEKSWTADDYGVMN 243
Cdd:PHA03100 175 --------------VNYLLSYGVPINIKDVYGFTPLHYAVYN 202
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
30-228 |
2.38e-16 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 83.50 E-value: 2.38e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 30 YELKDkDLSKLHRAASAGDVGKIKQLIKKQDINQLDKEN-RTPLHIACANGQLDTVKVLLEHKSKLN-LCDNDNRSPLLK 107
Cdd:PHA02875 30 FEIYD-GISPIKLAMKFRDSEAIKLLMKHGAIPDVKYPDiESELHDAVEEGDVKAVEELLDLGKFADdVFYKDGMTPLHL 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 108 AIQCQQESCATVLLEHNADPNLVDINGNAALHLAALIPSVSIAKQLLEHGANINAFNKEGCTPLILAVTENNEEMVEFLL 187
Cdd:PHA02875 109 ATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLL 188
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1774923325 188 KEGADINACDRGGRTSLMISS-NNGQNNLVRILLQNEADINI 228
Cdd:PHA02875 189 DSGANIDYFGKNGCVAALCYAiENNKIDIVRLFIKRGADCNI 230
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
874-1567 |
2.85e-16 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 85.50 E-value: 2.85e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 874 RYKLLASKVKKMENEKKDLQ-QIAEKNRELKSmLDHQKVESESDLNSLRFTLKQEEEKRK---NAEMLYGKSQ------- 942
Cdd:TIGR02169 224 EGYELLKEKEALERQKEAIErQLASLEEELEK-LTEEISELEKRLEEIEQLLEELNKKIKdlgEEEQLRVKEKigeleae 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 943 -EQLRRKEDQCCQEMEAkqlLELTIRNLELEMRSMQNTVRQVEEERNEVQRLLSHEHNARIAQEDILNNIRRKSEEIEne 1021
Cdd:TIGR02169 303 iASLERSIAEKERELED---AEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVD-- 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1022 kmwTKNAEVHGQLSKIDEREKDLilqnsnlQEEMNVLKLELDHVRSQNQQEESKYMDENENLKEKIA----------DLR 1091
Cdd:TIGR02169 378 ---KEFAETRDELKDYREKLEKL-------KREINELKRELDRLQEELQRLSEELADLNAAIAGIEAkineleeekeDKA 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1092 RDLKMNEETLTQT---VIQYNSQLHALKTENTMLCSKLEHEKQGKDRLETELESIRSR--------------------LT 1148
Cdd:TIGR02169 448 LEIKKQEWKLEQLaadLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERvrggraveevlkasiqgvhgTV 527
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1149 STLQEVERNQALKIEV-------------------------ERTLQRERDEWLRSQDKLNHELSTIRENN---------- 1193
Cdd:TIGR02169 528 AQLGSVGERYATAIEVaagnrlnnvvveddavakeaiellkRRKAGRATFLPLNKMRDERRDLSILSEDGvigfavdlve 607
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1194 -------------------NNL-----------------------------SQQLIRAETKSNSLENELRQTNTSLQDKV 1225
Cdd:TIGR02169 608 fdpkyepafkyvfgdtlvvEDIeaarrlmgkyrmvtlegelfeksgamtggSRAPRGGILFSRSEPAELQRLRERLEGLK 687
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1226 ILSESTQRELTHTCGRIKELehtlqleKDKICKSTVKQESLQEKLAQIQSENMLLRQQIEDVNNKGIIKDKTVSDVQDKF 1305
Cdd:TIGR02169 688 RELSSLQSELRRIENRLDEL-------SQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSEL 760
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1306 TEIIAKIradAERQVQIieernkdliikyNETREQLYRLETEkvERESTLRQLQQELADALKKLSMSEASLEVITRYRND 1385
Cdd:TIGR02169 761 KELEARI---EELEEDL------------HKLEEALNDLEAR--LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNR 823
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1386 IEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEYSSAAAGDENAIKELEGHVQKLEI 1465
Cdd:TIGR02169 824 LTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELER 903
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1466 ENAKFEATAkQQAGQIDILQKELRETLSIRHK-LEELIASLQSSKMGL--EEKLNHQVHKQTALSQSAQDSHNL----WE 1538
Cdd:TIGR02169 904 KIEELEAQI-EKKRKRLSELKAKLEALEEELSeIEDPKGEDEEIPEEElsLEDVQAELQRVEEEIRALEPVNMLaiqeYE 982
|
810 820
....*....|....*....|....*....
gi 1774923325 1539 EELKSRSRLGIRLAELEHEKAEFADQVES 1567
Cdd:TIGR02169 983 EVLKRLDELKEKRAKLEEERKAILERIEE 1011
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1125-1845 |
9.39e-16 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 83.96 E-value: 9.39e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1125 KLEHEKQGKDRLETELESIRSRLtSTLQEvERNQALKIEVERTLQRERDEWLRSQDKLNHElstirennnnlsQQLIRAE 1204
Cdd:TIGR02169 178 ELEEVEENIERLDLIIDEKRQQL-ERLRR-EREKAERYQALLKEKREYEGYELLKEKEALE------------RQKEAIE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1205 TKSNSLENELRQTNTSLQDKVILSESTQRELTHTCGRIKELEHTLQLE-KDKICKSTVKQESLQEKLAqiqsenmLLRQQ 1283
Cdd:TIGR02169 244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIA-------EKERE 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1284 IEDVNNKGIIKDKTVSDVQDKFTEIIAKIRADAERQVQIIEErnkdliikYNETREQLYRLETEKVERESTLRQLQQELA 1363
Cdd:TIGR02169 317 LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEE--------YAELKEELEDLRAELEEVDKEFAETRDELK 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1364 DALKKLSMseaslevITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDK-------EREVMAVS 1436
Cdd:TIGR02169 389 DYREKLEK-------LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKaleikkqEWKLEQLA 461
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1437 QKVQEYSSAAAGDENAIKELEGHVQKLEIENAKFEATAKQ-QAGQIDI--LQKELRETLSIRHKL--------EELIASL 1505
Cdd:TIGR02169 462 ADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARAsEERVRGGraVEEVLKASIQGVHGTvaqlgsvgERYATAI 541
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1506 QSSKMG-------------------LEEK---------LNHQVHKQTALSQSAQDSH-----NLWE-------------- 1538
Cdd:TIGR02169 542 EVAAGNrlnnvvveddavakeaielLKRRkagratflpLNKMRDERRDLSILSEDGVigfavDLVEfdpkyepafkyvfg 621
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1539 -----EELKSRSRLGI--RLAELEHEKAEFADQVESEKKKVKKLIEHKRSMEARFDQEIKRNAELQRDISGLKKLLKTAK 1611
Cdd:TIGR02169 622 dtlvvEDIEAARRLMGkyRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIE 701
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1612 KKIKELesvgtQQSTQDGFKSTHfEKEIDIMKLKEKINELSFRLENESSNYKQLEaanRDLQQQLSSMKMFHKSQEHLEK 1691
Cdd:TIGR02169 702 NRLDEL-----SQELSDASRKIG-EIEKEIEQLEQEEEKLKERLEELEEDLSSLE---QEIENVKSELKELEARIEELEE 772
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1692 GKRQLEDEVANLKRQIEINKVDQslIEKHKREIEE-----RGRL-ELKQKLEEVNLFLQS-QAASQETLEQIRAAND--A 1762
Cdd:TIGR02169 773 DLHKLEEALNDLEARLSHSRIPE--IQAELSKLEEevsriEARLrEIEQKLNRLTLEKEYlEKEIQELQEQRIDLKEqiK 850
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1763 SVRNQMEH---RIQELESDLGKIKNAQQENMLQRESTQTELERFKELYNEELKNRNSLALKLERSNERLADANAKLLNER 1839
Cdd:TIGR02169 851 SIEKEIENlngKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALE 930
|
....*.
gi 1774923325 1840 QRTKSL 1845
Cdd:TIGR02169 931 EELSEI 936
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1266-1835 |
1.78e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 82.68 E-value: 1.78e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1266 LQEKLAQIQSEnmLLRQQIEDVNNKGIIKDKTVSDVQDKFTEIIAKIRAdAERQVQIIEERNKDLIIKYNETREQLYRLE 1345
Cdd:COG1196 218 LKEELKELEAE--LLLLKLRELEAELEELEAELEELEAELEELEAELAE-LEAELEELRLELEELELELEEAQAEEYELL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1346 TEKVERESTLRQLQQELADALKKLSMSEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLL 1425
Cdd:COG1196 295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1426 EDKEREVMAVSQKVQEYSSAAAGDENAIKELEGHVQKLEIENAKFEATAKQQAGQIDILQKELRETLSIRHKLEELIASL 1505
Cdd:COG1196 375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1506 QSSKMGLEEKLNHQVHKQTALSQSAQDSHnlwEEELKSRSRLGIRLAELEHEKAEFADQVESEKKKVKKLIEHKRSMEAR 1585
Cdd:COG1196 455 EEEEEALLELLAELLEEAALLEAALAELL---EELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG 531
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1586 FDQEIKRNAELQRDISGLKKLLKTAKKKIKELESVGTQQSTQDGFKSTHFEKEIDIMKLKEKINELSFRLENESSNYKQL 1665
Cdd:COG1196 532 VEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1666 EAANRDLQQQLSSMKMFHKSQEHLEKGKRQLEDEVANLKRQIEINKVDQSLIEKHKREIEERGRLELKQKLEEvnlfLQS 1745
Cdd:COG1196 612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL----AER 687
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1746 QAASQETLEQIRAANDASVRNQMEHRIQELESDLGKIKNAQQENMLQRESTQTELERFKELYNEELKNRNSLAlKLERSN 1825
Cdd:COG1196 688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP-DLEELE 766
|
570
....*....|
gi 1774923325 1826 ERLADANAKL 1835
Cdd:COG1196 767 RELERLEREI 776
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
46-257 |
3.26e-15 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 80.39 E-value: 3.26e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 46 AGDVGKIKQLIKKQD--INQLDKENRTPLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQESCATVLLEH 123
Cdd:PHA02874 11 SGDIEAIEKIIKNKGncINISVDETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLIDN 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 124 NADPNLVDIngnaalhlaaliPSVS--IAKQLLEHGANINAFNKEGCTPLILAVTENNEEMVEFLLKEGADINACDRGGR 201
Cdd:PHA02874 91 GVDTSILPI------------PCIEkdMIKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGC 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1774923325 202 TSLMISSNNGQNNLVRILLQNEADINIKDEKSWTADDYGVMNGHHACSHLIIEHGS 257
Cdd:PHA02874 159 YPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIKLLIDHGN 214
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
875-1478 |
4.82e-15 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 81.26 E-value: 4.82e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 875 YKLLASKVKKMENEKKDLQQIAEKNRELKSMLDHQKVESESDLNSLRFTLKQEEEKRKNAEMLYGKSQEQLRRKEdqccq 954
Cdd:PRK03918 164 YKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKE----- 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 955 EMEAkqlLELTIRNLELEMRSMQNTVRQVEEERNEVQRLLSHehnariaqediLNNIRRKSEEIENEKmwTKNAEVHGQL 1034
Cdd:PRK03918 239 EIEE---LEKELESLEGSKRKLEEKIRELEERIEELKKEIEE-----------LEEKVKELKELKEKA--EEYIKLSEFY 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1035 SKIDEREKDLILQNSNLQEEMNVLKLELdhvrsqnqQEESKYMDENENLKEKIADLRRDLKMNEET--LTQTVIQYNSQL 1112
Cdd:PRK03918 303 EEYLDELREIEKRLSRLEEEINGIEERI--------KELEEKEERLEELKKKLKELEKRLEELEERheLYEEAKAKKEEL 374
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1113 HALKTENT-----MLCSKLEHEKQGKDRLETELESIRSRLTSTLQEVERNQALKIEVER------TLQRERDEwlrsqdk 1181
Cdd:PRK03918 375 ERLKKRLTgltpeKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpVCGRELTE------- 447
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1182 lNHELSTIRENN---NNLSQQLIRAETKSNSLENELRQTntslqDKVILSESTQRELTHTCGRIKELEHTLQ-LEKDKIC 1257
Cdd:PRK03918 448 -EHRKELLEEYTaelKRIEKELKEIEEKERKLRKELREL-----EKVLKKESELIKLKELAEQLKELEEKLKkYNLEELE 521
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1258 KSTVKQESLQEKLAQIQSENMLLRQQIE---DVNNKGIIKDKTVSDVQDKFTEIIAKIRADAERQVQIIEERNKDLIIKY 1334
Cdd:PRK03918 522 KKAEEYEKLKEKLIKLKGEIKSLKKELEkleELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFY 601
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1335 NETREqLYRLETEKVERESTLRQLQQELADALKKLSMSEASLEVITRYRNDI-----EGEKQILQKEVEKFRIKVQDLEE 1409
Cdd:PRK03918 602 NEYLE-LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELekkysEEEYEELREEYLELSRELAGLRA 680
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1774923325 1410 QCNQAERLHHQLKNLLEDKEREVMAVSQKVQEYSSAaagdENAIKELEGHVQKLeienAKFEATAKQQA 1478
Cdd:PRK03918 681 ELEELEKRREEIKKTLEKLKEELEEREKAKKELEKL----EKALERVEELREKV----KKYKALLKERA 741
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
74-230 |
4.92e-15 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 80.07 E-value: 4.92e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 74 IACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQESCATV---LLEHNADPNLVDINGNAALHLAALIPSV-SI 149
Cdd:PHA03095 20 LNASNVTVEEVRRLLAAGADVNFRGEYGKTPLHLYLHYSSEKVKDIvrlLLEAGADVNAPERCGFTPLHLYLYNATTlDV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 150 AKQLLEHGANINAFNKEGCTPL--ILAVTENNEEMVEFLLKEGADINACDRGGRTSL--MISSNNGQNNLVRILLQNEAD 225
Cdd:PHA03095 100 IKLLIKAGADVNAKDKVGRTPLhvYLSGFNINPKVIRLLLRKGADVNALDLYGMTPLavLLKSRNANVELLRLLIDAGAD 179
|
....*
gi 1774923325 226 INIKD 230
Cdd:PHA03095 180 VYAVD 184
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
38-195 |
7.26e-15 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 80.68 E-value: 7.26e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 38 SKLHRAASAGDVGKIKQLIK-KQDINQLDKENRTPLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQESC 116
Cdd:PLN03192 527 SNLLTVASTGNAALLEELLKaKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKI 606
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 117 ATVL--LEHNADPNLvdinGNAALHLAALIPSVSIAKQLLEHGANINAFNKEGCTPLILAVTENNEEMVEFLLKEGADIN 194
Cdd:PLN03192 607 FRILyhFASISDPHA----AGDLLCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLLIMNGADVD 682
|
.
gi 1774923325 195 A 195
Cdd:PLN03192 683 K 683
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
171-262 |
1.17e-14 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 71.30 E-value: 1.17e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 171 LILAVTENNEEMVEFLLKEGADINACDRGGRTSLMISSNNGQNNLVRILLqNEADINIKDEKsWTADDYGVMNGHHACSH 250
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLL-EHADVNLKDNG-RTALHYAARSGHLEIVK 78
|
90
....*....|..
gi 1774923325 251 LIIEHGSKKRVN 262
Cdd:pfam12796 79 LLLEKGADINVK 90
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
886-1850 |
1.46e-14 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 79.83 E-value: 1.46e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 886 ENEKKDLQQIAEKNR----------------ELKSMLDHQKVESESDLNSLRFTLKQEEEKRKNAEMLYGKSQEQLRRKE 949
Cdd:pfam01576 30 ELEKKHQQLCEEKNAlqeqlqaetelcaeaeEMRARLAARKQELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 950 DQCCQEMEAKQLLELTIRNLELEMRSMQNTVRQVEEERNEVQRllshehNARIAQEDILNNIRRKSEEIENEKMWTKNAE 1029
Cdd:pfam01576 110 EQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSK------ERKLLEERISEFTSNLAEEEEKAKSLSKLKN 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1030 VH-GQLSKIDEREKdlilqnsnlQEEMnvLKLELDHVRSQNQQEESKYMDENENLKEKIADLRRDLKMNEETLTQTVIQY 1108
Cdd:pfam01576 184 KHeAMISDLEERLK---------KEEK--GRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARL 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1109 NS----------QLHALKTENTMLCSKLEHEKQGKDR-------LETELESIRSRLTSTLQEVERNQALKIEVER---TL 1168
Cdd:pfam01576 253 EEetaqknnalkKIRELEAQISELQEDLESERAARNKaekqrrdLGEELEALKTELEDTLDTTAAQQELRSKREQevtEL 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1169 QRERDEWLRSQD---------------KLNHELSTIRENNNNLSQQLIRAETKSNSLENELRQTNTSLQDkvilSEStqr 1233
Cdd:pfam01576 333 KKALEEETRSHEaqlqemrqkhtqaleELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQD----SEH--- 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1234 elthtcgRIKELEHTLQLEKDKICKSTVKQESLQEKLAQIQSENMLLRQQIEDVNNKGIIKDKTVSDVQDKFTEiIAKIR 1313
Cdd:pfam01576 406 -------KRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQD-TQELL 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1314 ADAERQVQIIEERNKDLIIKYNETREQLYRLETEKVERESTLRQLQQELADALKKLSMSEASLEVitryrndIEGEKQIL 1393
Cdd:pfam01576 478 QEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEA-------LEEGKKRL 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1394 QKEVEKfriKVQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEYSSaaagdenaikeLEGHVQKLEIENAKFEAT 1473
Cdd:pfam01576 551 QRELEA---LTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSN-----------LEKKQKKFDQMLAEEKAI 616
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1474 AKQQAGQIDILQKELRE----TLSIRHKLEEliasLQSSKMGLEEKLNHQVHKQTALSQSAQDSHNLWEEELKSRSRLGI 1549
Cdd:pfam01576 617 SARYAEERDRAEAEAREketrALSLARALEE----ALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQ 692
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1550 RLAELEHEKAEFADQVESEKKKVKKLIEHKRSMEARFDQEIKRNAELQRDisGLKKLLKTAKKKIKELESVGTQQSTQDG 1629
Cdd:pfam01576 693 QVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEE--KRRQLVKQVRELEAELEDERKQRAQAVA 770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1630 FKSthfEKEIDIMKLKEKINELSFRLENESSNYKQLEAANRDLQQQLSSMKMfhkSQEHLEKGKRQLEDEVANLKRQIEI 1709
Cdd:pfam01576 771 AKK---KLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARA---SRDEILAQSKESEKKLKNLEAELLQ 844
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1710 NKVDQSLIEKHKREIE-ERGRLElkqklEEVNLFLQSQAASQETLEQIRAAndasvRNQMEHRIQELESDLGKIKNAQQE 1788
Cdd:pfam01576 845 LQEDLAASERARRQAQqERDELA-----DEIASGASGKSALQDEKRRLEAR-----IAQLEEELEEEQSNTELLNDRLRK 914
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1774923325 1789 NMLQRESTQTEL--ERFKELYNEELKNrnslalKLERSNERLadaNAKLLNERQRTKSLIASSI 1850
Cdd:pfam01576 915 STLQVEQLTTELaaERSTSQKSESARQ------QLERQNKEL---KAKLQEMEGTVKSKFKSSI 969
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
120-236 |
2.97e-14 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 77.76 E-value: 2.97e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 120 LLEHNADPNLVDINGNAALHL---AALIPSVSIAKQLLEHGANINAFNKEGCTPLILAVTENNEE-MVEFLLKEGADINA 195
Cdd:PHA03095 33 LLAAGADVNFRGEYGKTPLHLylhYSSEKVKDIVRLLLEAGADVNAPERCGFTPLHLYLYNATTLdVIKLLIKAGADVNA 112
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1774923325 196 CDRGGRTSLMI--SSNNGQNNLVRILLQNEADINIKDEKSWTA 236
Cdd:PHA03095 113 KDKVGRTPLHVylSGFNINPKVIRLLLRKGADVNALDLYGMTP 155
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
882-1597 |
9.90e-14 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 77.08 E-value: 9.90e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 882 VKKMENEKKDLQQIAEKNRELKSMLDHQKVESESDLNSLRFTLKQEEEKRKNAEMLYGKSQEQLRRKEDQCCQEMEAKQL 961
Cdd:pfam15921 80 LEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKC 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 962 LELTIrnlelemrsMQNTVRQVEEERnevQRLLSHEhnariaqeDILNNIRrkSEEIENEKMWTKNAEVHGQLSKIDERE 1041
Cdd:pfam15921 160 LKEDM---------LEDSNTQIEQLR---KMMLSHE--------GVLQEIR--SILVDFEEASGKKIYEHDSMSTMHFRS 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1042 KDLILQN--SNLQEEMNVLKLELDHVRSQNQQEESKYMDENENL----KEKIADLRRDLKMNEETLTQTVIQYNSQLHAL 1115
Cdd:pfam15921 218 LGSAISKilRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLlqqhQDRIEQLISEHEVEITGLTEKASSARSQANSI 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1116 KTENTMLCSKLEHEKQGKDRLETELESIRSRLTSTLQEVERNQALKI-EVERTLQRERDEWLRSQDklnhELSTIRENNN 1194
Cdd:pfam15921 298 QSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIeELEKQLVLANSELTEART----ERDQFSQESG 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1195 NLSQQLIRAETKSNSLENEL---RQTNTSLQDK----VILSESTQRELTHTCGRIKELEHTLQLEKDKiCKSTV------ 1261
Cdd:pfam15921 374 NLDDQLQKLLADLHKREKELsleKEQNKRLWDRdtgnSITIDHLRRELDDRNMEVQRLEALLKAMKSE-CQGQMerqmaa 452
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1262 ---KQESLQEK---LAQIQSENMLLRQQIEDVNNKGIIKDKTVSDVQDKFTEIIAKIRADAERQVQIIEERNK-DLIIky 1334
Cdd:pfam15921 453 iqgKNESLEKVsslTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRvDLKL-- 530
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1335 netrEQLYRLETEkverESTLRQLQQElADALkKLSMSEASlEVITRYRNDIEG-----------------EKQILQKEV 1397
Cdd:pfam15921 531 ----QELQHLKNE----GDHLRNVQTE-CEAL-KLQMAEKD-KVIEILRQQIENmtqlvgqhgrtagamqvEKAQLEKEI 599
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1398 EKFRI--------------KVQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEYSSAAAGDENAIKEL--EGHVQ 1461
Cdd:pfam15921 600 NDRRLelqefkilkdkkdaKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLseDYEVL 679
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1462 KLEIENA--KFEATAKQQAGQIDILQKELRETLSIRHKLEELIASLQSSKMGLEEKLNHQVHK-----------QTALSQ 1528
Cdd:pfam15921 680 KRNFRNKseEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQidalqskiqflEEAMTN 759
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1774923325 1529 SAQDSHNLWEEelksRSRLGIRLAELEHEKAEFADQVESEKKKVKKLIEHKRSMEARFDQEIKRNAELQ 1597
Cdd:pfam15921 760 ANKEKHFLKEE----KNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQ 824
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
858-1742 |
1.56e-13 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 76.55 E-value: 1.56e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 858 QNIIHEYERTIQRENGRYKLLASKVKKMENEKK--DLQQIAEKNRELKS---MLDHQKV-ESESDLNSLRFTLKQEEEKR 931
Cdd:pfam02463 176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKalEYYQLKEKLELEEEyllYLDYLKLnEERIDLLQELLRDEQEEIES 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 932 KNAEMLYGKSQEQLRRKEDQccQEMEAKQLLELTIRNLELEMRSMQNTVRQVEEERNEVQRLLSHEHNARIAQEDILNNI 1011
Cdd:pfam02463 256 SKQEIEKEEEKLAQVLKENK--EEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1012 RRKSEEIENEKmwtKNAEVHGQLSKIDEREKDLILQNSNLQEEMNVLKLELDHVRSQNQQEESKYMDENENLKEKIADLR 1091
Cdd:pfam02463 334 KEEIEELEKEL---KELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLL 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1092 RDLKMNEETLTQTVIqyNSQLHALKTENTMLCSKLEHEKQGKDRLEtELESIRSRLTSTLQEVERNQALKIEVERTLQRE 1171
Cdd:pfam02463 411 LELARQLEDLLKEEK--KEELEILEEEEESIELKQGKLTEEKEELE-KQELKLLKDELELKKSEDLLKETQLVKLQEQLE 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1172 RDEWLRSQDKLNHELSTIREN-NNNLSQQLIRAETKSNSLENELRQTNTSLQDKVILSESTQRELTHTCGRIKELEHTLQ 1250
Cdd:pfam02463 488 LLLSRQKLEERSQKESKARSGlKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLV 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1251 LEKDKICKSTVKQESLQEKLAQIQSENMLLRQQIEDVNNKgIIKDKTVSDVQDKFTEIIAKIRADAERQVQIIEERNKDL 1330
Cdd:pfam02463 568 RALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQ-LDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1331 IIKYNETREqlyRLETEKVERESTLRQLQQELADALKKLSMSEASLEVITRYRNDiegEKQILQKEVEKFRIKVQDLEEQ 1410
Cdd:pfam02463 647 GLRKGVSLE---EGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQ---LEIKKKEQREKEELKKLKLEAE 720
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1411 CNQAERLHHQLKNLLEDKEREVMAVSQKVQEYssaaagdenaikeLEGHVQKLEIENAKFEATAKQQAgqiDILQKELRE 1490
Cdd:pfam02463 721 ELLADRVQEAQDKINEELKLLKQKIDEEEEEE-------------EKSRLKKEEKEEEKSELSLKEKE---LAEEREKTE 784
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1491 TLSIRHKLEELIASLQSSKMGLEEKLNHQVhKQTALSQSAQDSHNLWEEELKSRSRLGIRLAELEHEKAEFADQVESEKK 1570
Cdd:pfam02463 785 KLKVEEEKEEKLKAQEEELRALEEELKEEA-ELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEI 863
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1571 KVKKLIEHKRSMEARFDQEIKRNAELQRdisglkklLKTAKKKIKELESVGTQQSTQDGFKSTHFEKEIDIMKLKEKINE 1650
Cdd:pfam02463 864 TKEELLQELLLKEEELEEQKLKDELESK--------EEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEE 935
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1651 LSFRLENESSNYKQLEAANRDLQQQLsSMKMFHKSQEHLEKGKRQLEDEVANLKRQIEINKVDQSLIEKHKREIEERGRL 1730
Cdd:pfam02463 936 EPEELLLEEADEKEKEENNKEEEEER-NKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEE 1014
|
890
....*....|..
gi 1774923325 1731 ELKQKLEEVNLF 1742
Cdd:pfam02463 1015 TCQRLKEFLELF 1026
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1313-1847 |
2.12e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 76.13 E-value: 2.12e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1313 RADAERQVQIIEE---RNKDLIikyNETREQLYRLET--EKVER----ESTLRQLQQELA-----DALKKLSMSEASLEV 1378
Cdd:COG1196 174 KEEAERKLEATEEnleRLEDIL---GELERQLEPLERqaEKAERyrelKEELKELEAELLllklrELEAELEELEAELEE 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1379 ITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEYSSAAAGDENAIKELEG 1458
Cdd:COG1196 251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1459 HVQKLEIENAKFEATAKQQAGQIDILQKELRETLSIRHKLEELIASLQSSKMGLEEKLNHQVHKQTALSQSAQDSHNLWE 1538
Cdd:COG1196 331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1539 EELKSRSRLGIRLAELEHEKAEFADQVESEKKKVKKLIEHKRSMEARFDQEIKRNAELQRDISGLKKLLKTAKKKIKELE 1618
Cdd:COG1196 411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1619 SVGTQQSTQDGfKSTHFEKEIDIMKLKEKINELSFRLENESSNYKQLEAANRDLQQQLssmkMFHKSQEHLEKGKRQLED 1698
Cdd:COG1196 491 ARLLLLLEAEA-DYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAA----LQNIVVEDDEVAAAAIEY 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1699 EVANLK-----RQIEINKVDQSLIEKHKREIEERGRLELKQKLEEVNLFLQSQAASQ--ETLEQIRAANDASVRNQMEHR 1771
Cdd:COG1196 566 LKAAKAgratfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLlgRTLVAARLEAALRRAVTLAGR 645
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1774923325 1772 IQELESDLGKIKNAQQENMLQRESTQTELERFKELYNEELKNRNSLALKLERSNERLADANAKLLNERQRTKSLIA 1847
Cdd:COG1196 646 LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL 721
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
60-197 |
2.22e-13 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 74.92 E-value: 2.22e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 60 DINQLDKEN-RTPLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQESCATVLLEHNADPNLVDINGNAAL 138
Cdd:PHA02878 159 DINMKDRHKgNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPL 238
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1774923325 139 HLA-ALIPSVSIAKQLLEHGANINAFNK-EGCTPLILAVteNNEEMVEFLLKEGADINACD 197
Cdd:PHA02878 239 HISvGYCKDYDILKLLLEHGVDVNAKSYiLGLTALHSSI--KSERKLKLLLEYGADINSLN 297
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1303-1674 |
2.70e-13 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 75.87 E-value: 2.70e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1303 DKFTEIIAKIRADAERqvqiIEERNKDLIIKYNETREQLYRLETEKVEREStLRQLQQELADALKKLSMSEasLEVITRY 1382
Cdd:TIGR02169 166 AEFDRKKEKALEELEE----VEENIERLDLIIDEKRQQLERLRREREKAER-YQALLKEKREYEGYELLKE--KEALERQ 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1383 RNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDK-EREVMAVSQKVQEYSSAAAGDENAIKELEGHVQ 1461
Cdd:TIGR02169 239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERSIAEKERELE 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1462 KLEIENAKFEATAKQQAGQIDILQKELRETLSIRHKLEELIASLQSSKMGLEEKLnhqvhkqtalsQSAQDSHNLWEEEL 1541
Cdd:TIGR02169 319 DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAEL-----------EEVDKEFAETRDEL 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1542 KSRSRlgiRLAELEHEKaefadqvESEKKKVKKLIEHKRSMEARFDQeikRNAELQRDISGLKKLLKTAKKKIKELESVG 1621
Cdd:TIGR02169 388 KDYRE---KLEKLKREI-------NELKRELDRLQEELQRLSEELAD---LNAAIAGIEAKINELEEEKEDKALEIKKQE 454
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1774923325 1622 TQQSTQDGFKSTHFEKeidIMKLKEKINELSFRLENESSNYKQLEAANRDLQQ 1674
Cdd:TIGR02169 455 WKLEQLAADLSKYEQE---LYDLKEEYDRVEKELSKLQRELAEAEAQARASEE 504
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1011-1584 |
3.96e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 74.97 E-value: 3.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1011 IRRKSEEIENEKMWTKNAEVHGQLSKIDEREKDLILQNSNLQEEMNVLKLELDHVRSQNQQEESKYMDENE---NLKEKI 1087
Cdd:COG1196 218 LKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyELLAEL 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1088 ADLRRDLKMNEETLtqtvIQYNSQLHALKTENTMLCSKLEHEKQGKDRLETELESIRSRLTSTLQEVERNQALKIEVERT 1167
Cdd:COG1196 298 ARLEQDIARLEERR----RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1168 LQRERDEWLRSQDKLNHELSTIRENNNNLsQQLIRAETKSNSLENELRQTNTSLQDKVILSESTQRELTHTcgrIKELEH 1247
Cdd:COG1196 374 LAEAEEELEELAEELLEALRAAAELAAQL-EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA---LEEAAE 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1248 TLQLEKDKICKSTVKQESLQEKLAQIQSENMLLRQQIEDVNNKGIIKDKTVSDVQDKFTEIIAKIRADAERQV--QIIEE 1325
Cdd:COG1196 450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLagAVAVL 529
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1326 RNKDLIIKYNETREQLYRLETEKVERESTLRQLQQELADALKklsmSEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQ 1405
Cdd:COG1196 530 IGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKA----GRATFLPLDKIRARAALAAALARGAIGAAVDLVA 605
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1406 DLEEQCnqAERLHHQLKNLLED-------KEREVMAVSQKVQEYSSAAAGDENAIKELEGHVQKLEIENAKFEATAKQQA 1478
Cdd:COG1196 606 SDLREA--DARYYVLGDTLLGRtlvaarlEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEE 683
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1479 GQIDILQKELRETLSIRHKLEELIASLQSSKMGLEEKLNHQVHKQTALSQSAQDSHNLWEEElksrsrlgirlAELEHEK 1558
Cdd:COG1196 684 LAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEE-----------ELLEEEA 752
|
570 580
....*....|....*....|....*.
gi 1774923325 1559 AEFADQVESEKKKVKKLIEHKRSMEA 1584
Cdd:COG1196 753 LEELPEPPDLEELERELERLEREIEA 778
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
55-258 |
1.52e-12 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 72.79 E-value: 1.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 55 LIKKQDINQLDKENRTPLHIACANGQLDTVKVLLEHKSKLNL--------------CDN--------DNRS-------PL 105
Cdd:PHA02876 165 LEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIialddlsvlecavdSKNidtikaiiDNRSninkndlSL 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 106 LKAIQCQQESCATVLLEHNADPNLVDINGNAALHLAALIPSVS-IAKQLLEHGANINAFNKEGCTPL-ILAVTENNEEMV 183
Cdd:PHA02876 245 LKAIRNEDLETSLLLYDAGFSVNSIDDCKNTPLHHASQAPSLSrLVPKLLERGADVNAKNIKGETPLyLMAKNGYDTENI 324
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1774923325 184 EFLLKEGADINACDRGGRTSLMISSNNGQN-NLVRILLQNEADINIKDEKSWTADDYGVMNGHHACSHLIIEHGSK 258
Cdd:PHA02876 325 RTLIMLGADVNAADRLYITPLHQASTLDRNkDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGAD 400
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
858-1542 |
3.02e-12 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 72.39 E-value: 3.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 858 QNIIHEYERTIQRENGRYKLLA---SKVKKMENEKKDLQQIAEKNRELKSMLDHQKVE----SESDLNSLrFTLKQEEEK 930
Cdd:TIGR00606 237 REIVKSYENELDPLKNRLKEIEhnlSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKvfqgTDEQLNDL-YHNHQRTVR 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 931 RKNAEMLYGKSQEQLRRKEDQCCQEMEAKQLLELTIRNLELEMRSMQNTVRQVEEERNEVQRLLSHEHNARIAQEDILNN 1010
Cdd:TIGR00606 316 EKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNF 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1011 IRRKSEEIENE-KMWTKN--------AEVHGQLSKIDEREKDLILQNSNLQEEMNVLKLELDHVRSQNQQEESKYMDENE 1081
Cdd:TIGR00606 396 HTLVIERQEDEaKTAAQLcadlqskeRLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILE 475
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1082 NLKEKIADLRRDLKMNEETLTQTVIQYNSQLHALKTENTMLCSKLEHEKQGKDR---LETELESIRSRLTSTLQEVERNQ 1158
Cdd:TIGR00606 476 LDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHhttTRTQMEMLTKDKMDKDEQIRKIK 555
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1159 AL--------------KIEVERTLQRERDEWLRSQD---KLNHELSTIRENNNNLSQQLIRAETKSNSLENELRQTNTSL 1221
Cdd:TIGR00606 556 SRhsdeltsllgyfpnKKQLEDWLHSKSKEINQTRDrlaKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQ 635
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1222 QDKVILsESTQRELTHTCGRIKELEHTLQLEKDKICKSTVKQES--------------LQEKLAQIQSENMLLRQQIEDV 1287
Cdd:TIGR00606 636 DEESDL-ERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSccpvcqrvfqteaeLQEFISDLQSKLRLAPDKLKST 714
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1288 nnkgiikDKTVSDVQDKFTEIIAKiradAERQVQIIEERNKDLiikyNETREQLYRLETEKVERESTLRQLQQELADALK 1367
Cdd:TIGR00606 715 -------ESELKKKEKRRDEMLGL----APGRQSIIDLKEKEI----PELRNKLQKVNRDIQRLKNDIEEQETLLGTIMP 779
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1368 KLSMSEASLEVITryrndIEGEKQILQKEVEKfRIKVQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEYSSAAA 1447
Cdd:TIGR00606 780 EEESAKVCLTDVT-----IMERFQMELKDVER-KIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQ 853
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1448 GDENAIKELEGHVQKLEIENAKFeATAKQQAG----QIDILQKELRETLSIRHKLEELIASLQSSKMGLEEKLNHQVHKQ 1523
Cdd:TIGR00606 854 DQQEQIQHLKSKTNELKSEKLQI-GTNLQRRQqfeeQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSK 932
|
730
....*....|....*....
gi 1774923325 1524 TALSQSAQDSHNLWEEELK 1542
Cdd:TIGR00606 933 ETSNKKAQDKVNDIKEKVK 951
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1262-1843 |
4.62e-12 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 71.63 E-value: 4.62e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1262 KQESLQEKLAQIQSENMLLRQQIEDVNNKGIIKDKTVSDVQDKFTEIIAKIRADAERQVQIIEERNK--DLIIKYNETRE 1339
Cdd:PRK03918 159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKleKEVKELEELKE 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1340 QLYRLETEKVERESTLRQLQ---QELADALKKLSMSEASLEVITRYRNDIEGEKQ---ILQKEVEKFRIKVQDLEEQcnq 1413
Cdd:PRK03918 239 EIEELEKELESLEGSKRKLEekiRELEERIEELKKEIEELEEKVKELKELKEKAEeyiKLSEFYEEYLDELREIEKR--- 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1414 AERLHHQLKNL------LEDKEREVMAVSQKVQEYssaaagdENAIKELEGHVQKLEienakfeaTAKQQAGQIDILQKE 1487
Cdd:PRK03918 316 LSRLEEEINGIeerikeLEEKEERLEELKKKLKEL-------EKRLEELEERHELYE--------EAKAKKEELERLKKR 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1488 LREtLSIrHKLEELIASLQSSKMGLEEKLNHQVHKQTALSQSAQDSHNLWEEELKSRSRLGIRLAEL-EHEKAEfadqve 1566
Cdd:PRK03918 381 LTG-LTP-EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELtEEHRKE------ 452
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1567 sekkkvkkLIEHKRSMEARFDQEIKRNAELQRDISGLKKLLKTAKKKIKELEsvgTQQSTQDGFKSTHFE-KEIDIMKLK 1645
Cdd:PRK03918 453 --------LLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELI---KLKELAEQLKELEEKlKKYNLEELE 521
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1646 EKINElsFRLENESSNykQLEAANRDLQQQLSSMKMFHKSQEHLEKGKRQLEDEVANLKRQIEinKVDQSLIEKHKREIE 1725
Cdd:PRK03918 522 KKAEE--YEKLKEKLI--KLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELE--ELGFESVEELEERLK 595
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1726 E-----RGRLELKQKLEEVNLFLQSQAASQETLEQIRAandasvrnqmehRIQELESDLGKIKNAQQEnmLQRESTQtel 1800
Cdd:PRK03918 596 ElepfyNEYLELKDAEKELEREEKELKKLEEELDKAFE------------ELAETEKRLEELRKELEE--LEKKYSE--- 658
|
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 1774923325 1801 ERFKELYNEELKNRNSLALKLER--SNERLADANAKLLNERQRTK 1843
Cdd:PRK03918 659 EEYEELREEYLELSRELAGLRAEleELEKRREEIKKTLEKLKEEL 703
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
943-1805 |
1.66e-11 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 70.00 E-value: 1.66e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 943 EQLRRKEDQCCQEMEAKQLLELTIRNLELEMRSMQNTVRQVEEERNEVQRLLSHEHNARIAQEDILNNIRRKSEEIENEK 1022
Cdd:pfam02463 166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1023 MWTKNAEVHGQLSKIDEREKDLILQNSNLQEEMNVLKL---ELDHVRSQNQQEESKYMDENENLKEKIADLRRDLKMNE- 1098
Cdd:pfam02463 246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLqeeELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKk 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1099 -ETLTQTVIQYNSQLHALKTENTMLCSKLEHEKQGKDRLETELESIRSRLTSTLQEVERNQALKIEVERTLQRERDEWLR 1177
Cdd:pfam02463 326 aEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEK 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1178 SQDKLNHELSTIRENNNNLSQQLIRAETKSNSLENELRQTNTSLQDKVILSESTQRELTHTCGRIKELEHTLQLEKDKIC 1257
Cdd:pfam02463 406 EAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQ 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1258 KSTVKQESLQEKLAQIQSENmllRQQIEDVNNKGIIKDKTVSDVQDKFTEIIAKIRADAERQVQIIEERNKDLIIKYNET 1337
Cdd:pfam02463 486 LELLLSRQKLEERSQKESKA---RSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEE 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1338 REQLYRLETEKVERESTLRQLQQELADALKKLSmseasleviTRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCN---QA 1414
Cdd:pfam02463 563 RQKLVRALTELPLGARKLRLLIPKLKLPLKSIA---------VLEIDPILNLAQLDKATLEADEDDKRAKVVEGIlkdTE 633
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1415 ERLHHQLKNLLEDKEREVMAVSQKVQEYSSAAAGDENAIKELEgHVQKLEIENAKFEATAKQQAGQIDILQKELRETLSI 1494
Cdd:pfam02463 634 LTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELL-EIQELQEKAESELAKEEILRRQLEIKKKEQREKEEL 712
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1495 RHKLEELIASLQSSKMGLEEKLNhqvhkqTALSQSAQDSHNLWEEELKSRSRLGIRLAELEHEKAEFADQVESEKKKVKK 1574
Cdd:pfam02463 713 KKLKLEAEELLADRVQEAQDKIN------EELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKL 786
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1575 LIEHKRSMEARFDQEIKRNAELQRDISGLKKLLKTAKKKIKELESVGTQQSTQDGFKSTHFEKEIDIMKLKEKINELSFR 1654
Cdd:pfam02463 787 KVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKE 866
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1655 LENESSNYKQLEAANRDLQQQLSSMKMFHKSQEHLEKGKRQLEDEVANLKRQIEINKVDQSLIEKHKREIEERGRLE--- 1731
Cdd:pfam02463 867 ELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEead 946
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1774923325 1732 LKQKLEEVNLFLQSQAASQETLEQIRAANDASVRNQMEHRIQELESDLGKIKNAQQE-NMLQRESTQTELERFKE 1805
Cdd:pfam02463 947 EKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEkKKLIRAIIEETCQRLKE 1021
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
981-1816 |
2.78e-11 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 69.31 E-value: 2.78e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 981 RQVEEERNEVQRLLSHEHNARIAQEDILNNIRRKSEEIEN-----EKMWTKNAEVHGQLSKIDEREKDLILQNSNLQEEM 1055
Cdd:TIGR00606 213 KQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNrlkeiEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKM 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1056 NVLKLELDHvrsQNQQEESKYMDENENLKEKIADLRRDL-KMNEEtlTQTVIQYNSQLhalktENTMLCSKLEHEKQGKD 1134
Cdd:TIGR00606 293 EKVFQGTDE---QLNDLYHNHQRTVREKERELVDCQRELeKLNKE--RRLLNQEKTEL-----LVEQGRLQLQADRHQEH 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1135 RLETELESIRSRLTSTLQEVERNQALKIEVER--TLQRERDEwlrsqdklnHELSTIRENNNNLSQQLIRAETKSNSLEN 1212
Cdd:TIGR00606 363 IRARDSLIQSLATRLELDGFERGPFSERQIKNfhTLVIERQE---------DEAKTAAQLCADLQSKERLKQEQADEIRD 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1213 ELRQTNTSLQDKVILSESTQRELTHTCGRIKELEHTLQ--LEKDKICKSTVKQESLQEKLAQIQS---ENMLLRQQIEDV 1287
Cdd:TIGR00606 434 EKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDriLELDQELRKAERELSKAEKNSLTETlkkEVKSLQNEKADL 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1288 NNKGIIKDKTVSDVQD-----KFTEIIAKIRADAERQVQIIEERNKDLIIKY-------NETREQLYRLETEKVERESTL 1355
Cdd:TIGR00606 514 DRKLRKLDQEMEQLNHhtttrTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgyfpnkKQLEDWLHSKSKEINQTRDRL 593
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1356 RQLQQELADA----------LKKLSMSEASLE---VITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLK 1422
Cdd:TIGR00606 594 AKLNKELASLeqnknhinneLESKEEQLSSYEdklFDVCGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLT 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1423 NLLE----------DKEREVMAVSQKVQEYSSAAAgdeNAIKELEGHVQKLEIENAKFEATAKQQAGQIDILQKELREtl 1492
Cdd:TIGR00606 674 DENQsccpvcqrvfQTEAELQEFISDLQSKLRLAP---DKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPE-- 748
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1493 sIRHKLEELIASLQSSKMGLEEKlnhqvHKQTALSQSAQDSHNLWEEELKSRSRLGIRLAELEHEKAEFADQVESE--KK 1570
Cdd:TIGR00606 749 -LRNKLQKVNRDIQRLKNDIEEQ-----ETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSdlDR 822
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1571 KVKKLIEHKRSMEARFDQEIKRNAELQRDISGLKKLLKTAKKKIKELES----VGTQQSTQDGFKSTHFEKEIDIMKL-- 1644
Cdd:TIGR00606 823 TVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSeklqIGTNLQRRQQFEEQLVELSTEVQSLir 902
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1645 -----KEKINELSFRLENESSNYKQL----EAANRDLQQQLSSMK------------MFHKSQEHLEKGKRQLEDEVANL 1703
Cdd:TIGR00606 903 eikdaKEQDSPLETFLEKDQQEKEELisskETSNKKAQDKVNDIKekvknihgymkdIENKIQDGKDDYLKQKETELNTV 982
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1704 KRQIEINkvdqsliEKHKREIEERGRL--------ELKQKLEEVNLFLQSQAASQETLEQIRAANDASVRN----QMEHR 1771
Cdd:TIGR00606 983 NAQLEEC-------EKHQEKINEDMRLmrqdidtqKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQmqvlQMKQE 1055
|
890 900 910 920
....*....|....*....|....*....|....*....|....*.
gi 1774923325 1772 IQELESDLGKIKNAQQENMLQRESTQTELERFK-ELYNEELKNRNS 1816
Cdd:TIGR00606 1056 HQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKkELREPQFRDAEE 1101
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1192-1828 |
2.83e-11 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 68.89 E-value: 2.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1192 NNNNLSQQLiraETKSNSLENELRQTNT---SLQDKVILSESTQRELTHTcgrIKELEHTLQLEKDKICKSTVKQESLQE 1268
Cdd:TIGR04523 30 KQDTEEKQL---EKKLKTIKNELKNKEKelkNLDKNLNKDEEKINNSNNK---IKILEQQIKDLNDKLKKNKDKINKLNS 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1269 KLAQIQSENMLLRQQIedvnNKGIIKDKTVSDVQDKFTEIIAKIRADAERQVQIIEERNKdliiKYNETREQLYRLETEK 1348
Cdd:TIGR04523 104 DLSKINSEIKNDKEQK----NKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNN----KYNDLKKQKEELENEL 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1349 VERESTLRQLQQELADALKKLSMSEASLEVITRYR----------NDIEGEKQILQKEVEKfriKVQDLEEQCNQAERLH 1418
Cdd:TIGR04523 176 NLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIqknkslesqiSELKKQNNQLKDNIEK---KQQEINEKTTEISNTQ 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1419 HQLKNLLEDKEREVMAVSQKVQEYSSAaagdENAIKELEGHVQKLEIE------------NAKFEATAKQQAGQIDILQK 1486
Cdd:TIGR04523 253 TQLNQLKDEQNKIKKQLSEKQKELEQN----NKKIKELEKQLNQLKSEisdlnnqkeqdwNKELKSELKNQEKKLEEIQN 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1487 ELRETLSIRHKLEELIASLQSSKMGLEeklNHQVHKQTALSQSAQdshnlweeelksrsrlgiRLAELEHEKAEFADQVE 1566
Cdd:TIGR04523 329 QISQNNKIISQLNEQISQLKKELTNSE---SENSEKQRELEEKQN------------------EIEKLKKENQSYKQEIK 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1567 SekkkvkkLIEHKRSMEARFDQEIKRNAELQRDISGLKKLLKTAKKKIKELESVGTQQ-STQDGFKSTHFEKEIDIMKLK 1645
Cdd:TIGR04523 388 N-------LESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNnSEIKDLTNQDSVKELIIKNLD 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1646 EKINELSFRLENESSNYKQLEAANRDLQQQLSSMKMFHKSqehLEKGKRQLEDEVANLKRQIEINKVDQSLIEKHKREIE 1725
Cdd:TIGR04523 461 NTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKK---LNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKE 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1726 ERGRlELKQKLEEVNLFLQSQA------ASQETLEQIRAANDASVRNQME--HRIQELESDLGKIKNAQQENmlqrESTQ 1797
Cdd:TIGR04523 538 SKIS-DLEDELNKDDFELKKENlekeidEKNKEIEELKQTQKSLKKKQEEkqELIDQKEKEKKDLIKEIEEK----EKKI 612
|
650 660 670
....*....|....*....|....*....|.
gi 1774923325 1798 TELERFKELYNEELKNRNSLALKLERSNERL 1828
Cdd:TIGR04523 613 SSLEKELEKAKKENEKLSSIIKNIKSKKNKL 643
|
|
| PHA02798 |
PHA02798 |
ankyrin-like protein; Provisional |
48-232 |
3.06e-11 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 67.94 E-value: 3.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 48 DVGKIKQLIKKQDINQLDKENRT-PLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLlkaiqcqqescATVLlehnad 126
Cdd:PHA02798 17 KLSTVKLLIKSCNPNEIVNEYSIfQKYLQRDSPSTDIVKLFINLGANVNGLDNEYSTPL-----------CTIL------ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 127 PNLVDINGnaalhlaalipSVSIAKQLLEHGANINAFNKEGCTPLILAVTE---NNEEMVEFLLKEGADINACDRGGRTS 203
Cdd:PHA02798 80 SNIKDYKH-----------MLDIVKILIENGADINKKNSDGETPLYCLLSNgyiNNLEILLFMIENGADTTLLDKDGFTM 148
|
170 180 190
....*....|....*....|....*....|..
gi 1774923325 204 LMI---SSNNGQNNLVRILLQNEADINIKDEK 232
Cdd:PHA02798 149 LQVylqSNHHIDIEIIKLLLEKGVDINTHNNK 180
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
43-226 |
7.67e-11 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 67.40 E-value: 7.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 43 AASAGDVGKIKQLIKK-QDINQLDKENRTPLHIACA-NGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQESCATVL 120
Cdd:PHA02876 315 AKNGYDTENIRTLIMLgADVNAADRLYITPLHQASTlDRNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTL 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 121 LEHNADPNLVDINGNAALHLA--ALIPSVSIaKQLLEHGANINAFNKEGCTPLILAVTENNE-EMVEFLLKEGADINACD 197
Cdd:PHA02876 395 LDYGADIEALSQKIGTALHFAlcGTNPYMSV-KTLIDRGANVNSKNKDLSTPLHYACKKNCKlDVIEMLLDNGADVNAIN 473
|
170 180
....*....|....*....|....*....
gi 1774923325 198 RGGRTSLMISSnnGQNNLVRILLQNEADI 226
Cdd:PHA02876 474 IQNQYPLLIAL--EYHGIVNILLHYGAEL 500
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
33-175 |
8.70e-11 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 66.44 E-value: 8.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 33 KDKDLSKLHRAASAGDVGKIKQLIKK-QDINQLDKENRTPLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAI-Q 110
Cdd:PHA02878 165 RHKGNTALHYATENKDQRLTELLLSYgANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVgY 244
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1774923325 111 CQQESCATVLLEHNADPNLVD-INGNAALHLAalIPSVSIAKQLLEHGANINAFNKEGCTPLILAV 175
Cdd:PHA02878 245 CKDYDILKLLLEHGVDVNAKSyILGLTALHSS--IKSERKLKLLLEYGADINSLNSYKLTPLSSAV 308
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
29-260 |
1.13e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 66.63 E-value: 1.13e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 29 GYELKDKDLSK---LHRAASAGDVGKI--KQLIKKQDINQLDKENRTPLHIACANG-QLDTVKVLLEHKSKLNLCDNDNR 102
Cdd:PHA02876 263 GFSVNSIDDCKntpLHHASQAPSLSRLvpKLLERGADVNAKNIKGETPLYLMAKNGyDTENIRTLIMLGADVNAADRLYI 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 103 SPLLKAIQCQQ-ESCATVLLEHNADPNLVDINGNAALHLAALIPSVSIAKQLLEHGANINAFNKEGCTPLILAVTENNEE 181
Cdd:PHA02876 343 TPLHQASTLDRnKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFALCGTNPY 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 182 M-VEFLLKEGADINACDRGGRTSLMIS-SNNGQNNLVRILLQNEAD---INIKDEKSWTaddygVMNGHHACSHLIIEHG 256
Cdd:PHA02876 423 MsVKTLIDRGANVNSKNKDLSTPLHYAcKKNCKLDVIEMLLDNGADvnaINIQNQYPLL-----IALEYHGIVNILLHYG 497
|
....
gi 1774923325 257 SKKR 260
Cdd:PHA02876 498 AELR 501
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1325-1709 |
1.41e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 66.62 E-value: 1.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1325 ERNKDLIIKYNETREQLYRLETEKVERESTLR--QLQQELADALKKLS--MSEASLEVITryrndieGEKQILQKEVEKF 1400
Cdd:TIGR02168 172 ERRKETERKLERTRENLDRLEDILNELERQLKslERQAEKAERYKELKaeLRELELALLV-------LRLEELREELEEL 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1401 RIKVQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEYSSAAAGDENAIKELEGHVQKLEIENAKFEATAKQQAGQ 1480
Cdd:TIGR02168 245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQ 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1481 IDILQKELRETLSIRHKLEELIASLQSSKMGLEEKLNHQVHKQTALSQSAQDshnlWEEELKSRSRlgiRLAELEHEKAE 1560
Cdd:TIGR02168 325 LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE----LEEQLETLRS---KVAQLELQIAS 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1561 FADQVESekkkvkkLIEHKRSMEARFDQEIKRNAELQRDISglkklLKTAKKKIKELESVGTQQSTQDGFKSTHFEKEID 1640
Cdd:TIGR02168 398 LNNEIER-------LEARLERLEDRRERLQQEIEELLKKLE-----EAELKELQAELEELEEELEELQEELERLEEALEE 465
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1774923325 1641 IMKLKEKINELSFRLENESSNYKQLEAANRDLQQQLSSmkmFHKSQEHLEKGKRQLEDEVANLKRQIEI 1709
Cdd:TIGR02168 466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLEG---FSEGVKALLKNQSGLSGILGVLSELISV 531
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
923-1562 |
1.97e-10 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 66.15 E-value: 1.97e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 923 TLKQEEEKRKNAEMLYGKSQEQLRRKEDQCCQEMEAKQLLELTIRNLELEMRSMQNT---VRQVEEERNEVQRLLSHEHN 999
Cdd:TIGR00618 185 EFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQShayLTQKREAQEEQLKKQQLLKQ 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1000 ARIAQEDILNNIRRKS---EEIENEKMWTKNAEVHGQLSKIDereKDLILQNSNLQEEMNVLKLELDHVRSQNQQEESKY 1076
Cdd:TIGR00618 265 LRARIEELRAQEAVLEetqERINRARKAAPLAAHIKAVTQIE---QQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIE 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1077 M------------DENENLKEKiADLRRDLKMNEETLTQTVIQYNSQLHALKTENTMLCSKLEHEKQGKDRLETELESir 1144
Cdd:TIGR00618 342 EqrrllqtlhsqeIHIRDAHEV-ATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSA-- 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1145 srltstlQEVERNQALKIEVERTLQRERDEWLRSQDKLNHELSTIRENNNNLSQQLIRAET-KSNSLENELRQTNTSLQD 1223
Cdd:TIGR00618 419 -------FRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREqQLQTKEQIHLQETRKKAV 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1224 KVILSESTQRELTHTCGRIKELEHTLQL------EKDKICKSTVKQESLQEKLAQIQSENMLLRQQIEDVNNKGIIKDKT 1297
Cdd:TIGR00618 492 VLARLLELQEEPCPLCGSCIHPNPARQDidnpgpLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQS 571
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1298 VSDVQDK---FTEIIAKIRADAERQVQIIEERNKDLIIKYNETREQLYRLETE--KVERESTLRQLQQELADALKKLSMS 1372
Cdd:TIGR00618 572 FSILTQCdnrSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEqdLQDVRLHLQQCSQELALKLTALHAL 651
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1373 EASL------EVITRYRNDIEGEKQILQKEVEKFRIKVQDL---EEQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEYS 1443
Cdd:TIGR00618 652 QLTLtqervrEHALSIRVLPKELLASRQLALQKMQSEKEQLtywKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLG 731
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1444 SAAAGDENAIKELEGHVQKLEIENAKFEATAKQQAGQ--------IDILQKELRETLSIRHKLEELIASLQSSKMGLEEK 1515
Cdd:TIGR00618 732 SDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEevtaalqtGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQE 811
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|.
gi 1774923325 1516 LNHQVHKQTA----LSQSAQDSHNLWEEELKSRSRLGIRLAELEHEKAEFA 1562
Cdd:TIGR00618 812 IPSDEDILNLqcetLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLA 862
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1046-1501 |
2.00e-10 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 66.20 E-value: 2.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1046 LQNSNLQEEMNVLKlELDHVRSQ--NQQEESKYMDENENLKEKIA----DLRRDLKMNEETLTQTVIQYNSQLHALKTEN 1119
Cdd:TIGR04523 27 IANKQDTEEKQLEK-KLKTIKNElkNKEKELKNLDKNLNKDEEKInnsnNKIKILEQQIKDLNDKLKKNKDKINKLNSDL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1120 TMLCSKLEHEKQGKDRLETELesirSRLTSTLQEVERNQAL-KIEVER-------------TLQRERDEWLRSQDKLNHE 1185
Cdd:TIGR04523 106 SKINSEIKNDKEQKNKLEVEL----NKLEKQKKENKKNIDKfLTEIKKkekeleklnnkynDLKKQKEELENELNLLEKE 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1186 LSTIRENNNNLSQQLIRAETKSNSLEnELRQTNTSLQDKVILSESTQrelthtcgriKELEHTLQLEKDKICKSTVKQES 1265
Cdd:TIGR04523 182 KLNIQKNIDKIKNKLLKLELLLSNLK-KKIQKNKSLESQISELKKQN----------NQLKDNIEKKQQEINEKTTEISN 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1266 LQEKLAQIQSENMLLRQQIEDVNNKGIIKDKTVSDVQDKFTEIIAKIrADAERQVQiiEERNKDLIIKYNETREQLYRLE 1345
Cdd:TIGR04523 251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEI-SDLNNQKE--QDWNKELKSELKNQEKKLEEIQ 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1346 TEKVERESTLRQLQQELADALKKLSMSEASLEVITRYRN-------DIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLH 1418
Cdd:TIGR04523 328 NQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEekqneieKLKKENQSYKQEIKNLESQINDLESKIQNQEKLN 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1419 HQLKNLLEDKEREVMAVSQKVQEYSSAAAGDENAIKELEGHVQKLEIENAKFEATAKQQAGQIDILQKELRetlSIRHKL 1498
Cdd:TIGR04523 408 QQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSIN---KIKQNL 484
|
...
gi 1774923325 1499 EEL 1501
Cdd:TIGR04523 485 EQK 487
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
68-257 |
2.59e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 64.63 E-value: 2.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 68 NRTPLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQESCATVLLEHNADPNLVDINGNAALHLAALIPSV 147
Cdd:PHA02875 2 DQVALCDAILFGELDIARRLLDIGINPNFEIYDGISPIKLAMKFRDSEAIKLLMKHGAIPDVKYPDIESELHDAVEEGDV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 148 SIAKQLLEHGANIN-AFNKEGCTPLILAVTENNEEMVEFLLKEGADINACDRGGRTSLMISSNNGQNNLVRILLQNEADI 226
Cdd:PHA02875 82 KAVEELLDLGKFADdVFYKDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACL 161
|
170 180 190
....*....|....*....|....*....|.
gi 1774923325 227 NIKDEKSWTADDYGVMNGHHACSHLIIEHGS 257
Cdd:PHA02875 162 DIEDCCGCTPLIIAMAKGDIAICKMLLDSGA 192
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
856-1381 |
3.25e-10 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 65.51 E-value: 3.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 856 KFQNIIHEYERTIQRENGRYKLLASKVKKMENEKKDLQQIAEKNRELKSMLDHQ-KVESE-------------SDLNSLR 921
Cdd:pfam05483 223 KIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKtKLQDEnlkeliekkdhltKELEDIK 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 922 FTLKQEEEKRKNAE---MLYGKSQEQL-RRKEDQCCQEMEAKQLLELTIRNLELEMRSMQNTVRQVEE--ERNEVQ-RLL 994
Cdd:pfam05483 303 MSLQRSMSTQKALEedlQIATKTICQLtEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQrlEKNEDQlKII 382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 995 SHEHNARIAQED----ILNNIRRKSEEI-----ENEKMWTKNAEVHGQLSKIDEREKDLILQNSNLQEEMNVLKLELDHV 1065
Cdd:pfam05483 383 TMELQKKSSELEemtkFKNNKEVELEELkkilaEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAI 462
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1066 RSQNQQ-----EESKYMDENENLK--------EKIADLRRDLKMNEETLTQTVIQYNSQLHALKTENTMLCSKLEHEKQG 1132
Cdd:pfam05483 463 KTSEEHylkevEDLKTELEKEKLKnieltahcDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEK 542
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1133 KDRLETELESIRSRLTSTLQEVERNQALKIEVERTLQRErdewlrsQDKLNHELSTIRENNNNLSQQLiraETKSNSLEn 1212
Cdd:pfam05483 543 EMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYE-------VLKKEKQMKILENKCNNLKKQI---ENKNKNIE- 611
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1213 ELRQTNTSLQDKvilSESTQRELTHTCGRIKELEHTLQLEKDKICKST-VKQESLQEKlaQIQSENMLlrqqiEDVNNKG 1291
Cdd:pfam05483 612 ELHQENKALKKK---GSAENKQLNAYEIKVNKLELELASAKQKFEEIIdNYQKEIEDK--KISEEKLL-----EEVEKAK 681
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1292 IIKDKTVS-------DVQDKFTEIIAKIRADAERQVQIIEERNKDLIIKYNETREQlyrlETEKVERESTLRQLQQELAD 1364
Cdd:pfam05483 682 AIADEAVKlqkeidkRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQ----SSAKAALEIELSNIKAELLS 757
|
570
....*....|....*..
gi 1774923325 1365 ALKKLSMSEASLEVITR 1381
Cdd:pfam05483 758 LKKQLEIEKEEKEKLKM 774
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
876-1518 |
3.72e-10 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 65.04 E-value: 3.72e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 876 KLLASKVKKMENEKKDLQQIAEKNRELKSMLDHQKVESESDLNSLRFTLKQEEEKRKNAEMLYGKSQEQLRRKEDQccqe 955
Cdd:TIGR04523 43 KTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQ---- 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 956 meakqlleltIRNLELEMRSMQNTVRQVEEERNEVQRLLSHEHNARIAQEDILNNIRRKSEEIENEKMWTKNaevhgQLS 1035
Cdd:TIGR04523 119 ----------KNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEK-----EKL 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1036 KIDEREKDLILQNSNLQEEMNVLKleldhvrsqnqqeesKYMDENENLKEKIADLRR---DLKMNEETLTQTVIQYNSQL 1112
Cdd:TIGR04523 184 NIQKNIDKIKNKLLKLELLLSNLK---------------KKIQKNKSLESQISELKKqnnQLKDNIEKKQQEINEKTTEI 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1113 HALKTENTMLCSKLEHEKQGKDRLETELESIR---SRLTSTLQEVERN-QALKIEVERTLQRERDEWLRSQDK----LNH 1184
Cdd:TIGR04523 249 SNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNkkiKELEKQLNQLKSEiSDLNNQKEQDWNKELKSELKNQEKkleeIQN 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1185 ELSTIRENNNNLSQQLIRAETKSNSLENELRQTNTSLQDKVILSESTQRELTHTCGRIKELEHTLQLEKDKICKSTVKQE 1264
Cdd:TIGR04523 329 QISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQ 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1265 SLQEKLAQIQSENMLLRQQIEDVNNKGIIKDKTVSDVQDKFTEIIAKIRaDAERQVQIIEERNKDLIIKYNETreqlyrl 1344
Cdd:TIGR04523 409 QKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIK-NLDNTRESLETQLKVLSRSINKI------- 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1345 etekverESTLRQLQQELADALKKLSMseaslevITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNL 1424
Cdd:TIGR04523 481 -------KQNLEQKQKELKSKEKELKK-------LNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDE 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1425 LEDK---------EREVMAVSQKVQEYSSAAAGDENAIKELEGHVQKLEIENAKFEATAKQQAGQIDILQKELRETLSIR 1495
Cdd:TIGR04523 547 LNKDdfelkkenlEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKEN 626
|
650 660
....*....|....*....|...
gi 1774923325 1496 HKLEELIASLQSSKMGLEEKLNH 1518
Cdd:TIGR04523 627 EKLSSIIKNIKSKKNKLKQEVKQ 649
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
38-206 |
6.19e-10 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 64.26 E-value: 6.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 38 SKLHRAASAGDVGKIKQLIKKQDINQLDK--ENRTPLHIACANGQLDTVKVLLEhksklnlcdndnrspllkaiqcqqes 115
Cdd:cd22192 19 SPLLLAAKENDVQAIKKLLKCPSCDLFQRgaLGETALHVAALYDNLEAAVVLME-------------------------- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 116 catvllehnADPNLVDI-------NGNAALHLAALIPSVSIAKQLLEHGANIN-------AFNKEGCT-------PLILA 174
Cdd:cd22192 73 ---------AAPELVNEpmtsdlyQGETALHIAVVNQNLNLVRELIARGADVVspratgtFFRPGPKNliyygehPLSFA 143
|
170 180 190
....*....|....*....|....*....|..
gi 1774923325 175 VTENNEEMVEFLLKEGADINACDRGGRTSLMI 206
Cdd:cd22192 144 ACVGNEEIVRLLIEHGADIRAQDSLGNTVLHI 175
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
117-188 |
9.51e-10 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 63.76 E-value: 9.51e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1774923325 117 ATVLLEHNADPNLVDINGNAALHLAALIPSVSIAKQLLEHGANINAFNKEGCTPLILAVTENNEEMVEFLLK 188
Cdd:PTZ00322 98 ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSR 169
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
856-1424 |
1.21e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.80 E-value: 1.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 856 KFQNIIHEYERTIQRENGRYKLLASKVKKMENEKKDLQQIAEKNRELKSMLDHQKVESESDLNSLRFTLKQEEEKRKNAE 935
Cdd:COG1196 243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELE 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 936 mlygksqEQLRRKEDQCCQEMEAKQLLELTIRNLELEMRSMQNTVRQVEEERNEVQRLLSHEHNARIAQEDILNNIRRKS 1015
Cdd:COG1196 323 -------EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1016 EEIENekmwtknaevhgQLSKIDEREKDLILQNSNLQEEMNVLKLELDHVRSQNQQEESKYMDENENLKEKIADLRRDLK 1095
Cdd:COG1196 396 AELAA------------QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1096 MNEETLTQTvIQYNSQLHALKTENTMLCSKLEHEKQGKDRLETELESIRSRLTSTLQEvernqalkiEVERTLQRERDEW 1175
Cdd:COG1196 464 LLAELLEEA-ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR---------GLAGAVAVLIGVE 533
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1176 LRSQDKLNHELSTIRENNNNLSQQLIRAETKSNSLENELRQTNTSLqDKVILSESTQRELTHTCGRIKELEHTLQLEKDK 1255
Cdd:COG1196 534 AAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPL-DKIRARAALAAALARGAIGAAVDLVASDLREAD 612
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1256 ICKSTVKQESLQEKLAQIQSENMLLRQQIEDVNNKGIIKDKTVSDVQDKFTEIIAKIRADAERQVQIIEERNKDLIIKYN 1335
Cdd:COG1196 613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1336 ETREQLYRLETEKVEREStlRQLQQELADALKKLSMSEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAE 1415
Cdd:COG1196 693 LELEEALLAEEEEERELA--EAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
|
....*....
gi 1774923325 1416 RLHHQLKNL 1424
Cdd:COG1196 771 RLEREIEAL 779
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
1128-1840 |
1.24e-09 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 63.59 E-value: 1.24e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1128 HEKQGKDRLETELESIRSRLTSTL-QEVERNQALKIEVERTLQRErdewlrsQDKLNHELSTIRENNNNLSQQLIRAETK 1206
Cdd:pfam05483 60 HYQEGLKDSDFENSEGLSRLYSKLyKEAEKIKKWKVSIEAELKQK-------ENKLQENRKIIEAQRKAIQELQFENEKV 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1207 SNSLENELrQTNTSLQDKVILSESTQRELTHTCGRIKELEHTLQLEKDKICKSTVKQESLQEKLAQIQSEnmlLRQQIED 1286
Cdd:pfam05483 133 SLKLEEEI-QENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEE---LRVQAEN 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1287 VNNKGIIKDKTVSDVQDKFTEIIAKIRADAERQVQII-------EERNKDLIIKYNETREQLYRLETEKVERESTLRQL- 1358
Cdd:pfam05483 209 ARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLliqitekENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELi 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1359 --QQELADALKKLSMS-----------EASLEVITRYRNDIEGEKQILQKEVEKFR----IKVQDLEEQCNQAERLHHQL 1421
Cdd:pfam05483 289 ekKDHLTKELEDIKMSlqrsmstqkalEEDLQIATKTICQLTEEKEAQMEELNKAKaahsFVVTEFEATTCSLEELLRTE 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1422 KNLLEDKEREVMAVSQKVQEYSSA-------AAGDENAIKELE---GHVQKLEIENAKFEATAKQQAGQIDILQKELRET 1491
Cdd:pfam05483 369 QQRLEKNEDQLKIITMELQKKSSEleemtkfKNNKEVELEELKkilAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAR 448
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1492 LSIRHKLEELIASLQSSKmgleeklnHQVHKQTALSQSAQDSHNLWEEELKSRS-RLGIRLAELEHEKAEFADQVESEKK 1570
Cdd:pfam05483 449 EKEIHDLEIQLTAIKTSE--------EHYLKEVEDLKTELEKEKLKNIELTAHCdKLLLENKELTQEASDMTLELKKHQE 520
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1571 KvkklIEHKRSMEARFDQEIKRNAELQRDISGLKKLLKTAKKKIKELESVGTQQSTQDGFKSTH--FEKEIDIMKLKEKI 1648
Cdd:pfam05483 521 D----IINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYevLKKEKQMKILENKC 596
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1649 NELSFRLENESSNYKQLEAANRDLQ-------QQLSSMKM-FHKSQEHLEKGKRQLEDEVANLKRQIEINKVDQS----L 1716
Cdd:pfam05483 597 NNLKKQIENKNKNIEELHQENKALKkkgsaenKQLNAYEIkVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEklleE 676
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1717 IEKHKREIEERGRLElkqklEEVNLFLQSQAASQETLEQIRaandasvRNQMEHRIQELESDLGKIKNAQQENMLQREST 1796
Cdd:pfam05483 677 VEKAKAIADEAVKLQ-----KEIDKRCQHKIAEMVALMEKH-------KHQYDKIIEERDSELGLYKNKEQEQSSAKAAL 744
|
730 740 750 760
....*....|....*....|....*....|....*....|....*.
gi 1774923325 1797 QTELERFKelyNEELKNRNSLALKLERSN--ERLADANAKLLNERQ 1840
Cdd:pfam05483 745 EIELSNIK---AELLSLKKQLEIEKEEKEklKMEAKENTAILKDKK 787
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
999-1506 |
2.62e-09 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 62.36 E-value: 2.62e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 999 NARIAQEDILNNIRRKSEEIENEKMWTKNAEVHGQLSKIDEREKDLILQNSNLQEEMNVLKLELDHVRSQNQQEESKyMD 1078
Cdd:PRK02224 173 DARLGVERVLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEER-RE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1079 ENENLKEKIADLRRDLKMNE---ETLTQTVIQYNSQLHALKTENTMLCSKLEHEKQGKDRLETELESIRSRLTSTLQEVE 1155
Cdd:PRK02224 252 ELETLEAEIEDLRETIAETErerEELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLE 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1156 ----RNQALKIEVERTLQR-----ERDEWLRSQ-DKLNHELSTIRENNNNLSQQLIRAETKSNSLENELRQTNTSLQDKV 1225
Cdd:PRK02224 332 ecrvAAQAHNEEAESLREDaddleERAEELREEaAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1226 ILSESTQRELTHTCGRIKELEHTLQLEKDKI--------------CKSTVKQ-------ESLQEKLAQIQSENMLLRQQI 1284
Cdd:PRK02224 412 DFLEELREERDELREREAELEATLRTARERVeeaealleagkcpeCGQPVEGsphvetiEEDRERVEELEAELEDLEEEV 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1285 EDVNNKgIIKDKTVSDVQDKfteiIAKIRADAERQVQIIEERNKDLiikyNETREQLYRLETEKVEREStlrQLQQELAD 1364
Cdd:PRK02224 492 EEVEER-LERAEDLVEAEDR----IERLEERREDLEELIAERRETI----EEKRERAEELRERAAELEA---EAEEKREA 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1365 ALKKLSMSEASLEVITryrnDIEGEKQILQKEVE---KFRIKVQDLEEQCNQAERLHHQLKNL--LEDKEREVMA-VSQK 1438
Cdd:PRK02224 560 AAEAEEEAEEAREEVA----ELNSKLAELKERIEsleRIRTLLAAIADAEDEIERLREKREALaeLNDERRERLAeKRER 635
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1774923325 1439 VQEYssAAAGDENAIKELEGHVQKLE--IENAKFEATAKQQA-----GQIDILQKELRETLSIRHKLEELIASLQ 1506
Cdd:PRK02224 636 KREL--EAEFDEARIEEAREDKERAEeyLEQVEEKLDELREErddlqAEIGAVENELEELEELRERREALENRVE 708
|
|
| trp |
TIGR00870 |
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ... |
75-235 |
2.83e-09 |
|
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 62.41 E-value: 2.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 75 ACANGQLDTVKVLLEHKSKLNLCDND--NRSPLLK-AIQCQQESCATVLLEHNADPNLvdinGNAALHLAAL-------- 143
Cdd:TIGR00870 24 AAERGDLASVYRDLEEPKKLNINCPDrlGRSALFVaAIENENLELTELLLNLSCRGAV----GDTLLHAISLeyvdavea 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 144 ---IPSVSIAKQLLEHGANINAFNKE--GCTPLILAVTENNEEMVEFLLKEGADINA---CD-----------RGGRTSL 204
Cdd:TIGR00870 100 illHLLAAFRKSGPLELANDQYTSEFtpGITALHLAAHRQNYEIVKLLLERGASVPAracGDffvksqgvdsfYHGESPL 179
|
170 180 190
....*....|....*....|....*....|.
gi 1774923325 205 MISSNNGQNNLVRILLQNEADINIKDEKSWT 235
Cdd:TIGR00870 180 NAAACLGSPSIVALLSEDPADILTADSLGNT 210
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
870-1155 |
9.01e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 60.85 E-value: 9.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 870 RENGRYKLLASKVKKMENEKKDLQQ-IAEKNRELKSMLDHQKVESES--DLNSLRFTLKQEEEKRKnaemlygKSQEQLR 946
Cdd:TIGR02169 671 SEPAELQRLRERLEGLKRELSSLQSeLRRIENRLDELSQELSDASRKigEIEKEIEQLEQEEEKLK-------ERLEELE 743
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 947 RKEDQCCQEMEAKqllELTIRNLELEMRSMQNTVRQVEEERNEVQRLLSHEhnariaqedILNNIRRKSEEIENEKmwtk 1026
Cdd:TIGR02169 744 EDLSSLEQEIENV---KSELKELEARIEELEEDLHKLEEALNDLEARLSHS---------RIPEIQAELSKLEEEV---- 807
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1027 nAEVHGQLSKIDEREKDLILQNSNLQEEMNVLKLELDHVRSQNQQEEskymDENENLKEKIADLRRDLKMNEETLTqtvi 1106
Cdd:TIGR02169 808 -SRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIE----KEIENLNGKKEELEEELEELEAALR---- 878
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1774923325 1107 QYNSQLHALKTENTMLCSKLEHEKQGKDRLETELESIRSR---LTSTLQEVE 1155
Cdd:TIGR02169 879 DLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRlseLKAKLEALE 930
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1241-1738 |
9.42e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 60.55 E-value: 9.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1241 RIKELEHTLQLEKDK---ICKSTVKQESLQEKLAQIQSENMLLRQQIEDVnnkgiikdktvsDVQDKFTEIIAKIRAdAE 1317
Cdd:COG4717 72 ELKELEEELKEAEEKeeeYAELQEELEELEEELEELEAELEELREELEKL------------EKLLQLLPLYQELEA-LE 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1318 RQVQIIEERNKDLiikyNETREQLYRLETEKVERESTLRQLQQELADALKKLS-MSEASLEVITRYRNDIEGEKQILQKE 1396
Cdd:COG4717 139 AELAELPERLEEL----EERLEELRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQRLAELEEE 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1397 VEKFRIKVQDLEEQCNQAE--RLHHQLKNLLEDKEREVMAVSQkVQEYSSAAAGDENAIKELEGhVQKLEIENAKFEATA 1474
Cdd:COG4717 215 LEEAQEELEELEEELEQLEneLEAAALEERLKEARLLLLIAAA-LLALLGLGGSLLSLILTIAG-VLFLVLGLLALLFLL 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1475 KQQAGQIDILQKELRETLSIRHKLEELIASLQSSKMGLEEKLnhQVHKQTALSQSAQDSHNLWEEELKSRSRLgiRLAEL 1554
Cdd:COG4717 293 LAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDL--SPEELLELLDRIEELQELLREAEELEEEL--QLEEL 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1555 EHEKAEFADQ--VESEKKKVKKLIEHKRSMEARfdqeiKRNAELQRDISGLKKLLKTAKKKIKELEsvgtqqstqdgfks 1632
Cdd:COG4717 369 EQEIAALLAEagVEDEEELRAALEQAEEYQELK-----EELEELEEQLEELLGELEELLEALDEEE-------------- 429
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1633 thfekeidimkLKEKINELSFRLENESSNYKQLEAANRDLQQQLSSMKMFHKSQEhLEKGKRQLEDEVANLKRQIEINKV 1712
Cdd:COG4717 430 -----------LEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAE-LLQELEELKAELRELAEEWAALKL 497
|
490 500
....*....|....*....|....*.
gi 1774923325 1713 DQSLIEKHKREIEERGRLELKQKLEE 1738
Cdd:COG4717 498 ALELLEEAREEYREERLPPVLERASE 523
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1166-1377 |
1.72e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 59.01 E-value: 1.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1166 RTLQRERDEWLRSQDKLNHELSTIRENNNNLSQQLIRAETKSNSLENELRQTNTSLQDkvilsesTQRELTHTCGRIKEL 1245
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAA-------LEAELAELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1246 EHTLQLEKDKIckstVKQESLQEKLAQIQSENMLLRQQIEDVNNKGIIKDKTVSDVQDKFTEIIAKIRADAERQVQIIEE 1325
Cdd:COG4942 96 RAELEAQKEEL----AELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1774923325 1326 RNKDLIIKYNETREQLYRLETEKVERESTLRQLQQELA---DALKKLSMSEASLE 1377
Cdd:COG4942 172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAelaAELAELQQEAEELE 226
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
134-187 |
1.74e-08 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 52.28 E-value: 1.74e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1774923325 134 GNAALHLAALIPSVSIAKQLLEHGANINAFNKEGCTPLILAVTENNEEMVEFLL 187
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1636-1876 |
1.93e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 58.62 E-value: 1.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1636 EKEIDIMKLKEKINELSFRLENESSNYKQLEAANRDLQQQLSSMKmfhKSQEHLEKGKRQLEDEVANLKRQIEINkvdQS 1715
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA---RRIRALEQELAALEAELAELEKEIAEL---RA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1716 LIEKHKREIEERGR-LELKQKLEEVNLFLQSQAASQ--ETLEQIRAANDAsvRNQMEHRIQELESDLGKIKNAQQENMLQ 1792
Cdd:COG4942 98 ELEAQKEELAELLRaLYRLGRQPPLALLLSPEDFLDavRRLQYLKYLAPA--RREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1793 RESTQTELERFKELYNEELKNRNSLALKLERSNERLADANAKLLNERQRTKSLIASSIMngslATSPVVDASSFGNFSNS 1872
Cdd:COG4942 176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA----EAAAAAERTPAAGFAAL 251
|
....
gi 1774923325 1873 GFRL 1876
Cdd:COG4942 252 KGKL 255
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1163-1725 |
2.50e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 59.31 E-value: 2.50e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1163 EVERTLQRERDEwlrsQDKLNHELSTIRENNNNLSQQLIRAETKSNSLENELRQtntsLQDKVILSESTQRELTHTCGRI 1242
Cdd:PRK03918 169 EVIKEIKRRIER----LEKFIKRTENIEELIKEKEKELEEVLREINEISSELPE----LREELEKLEKEVKELEELKEEI 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1243 KELE-HTLQLEKDKickstvkqESLQEKLAQIQSENMLLRQQIEDVNNKgiikdktvsdvqdkfTEIIAKIRADAERQVQ 1321
Cdd:PRK03918 241 EELEkELESLEGSK--------RKLEEKIRELEERIEELKKEIEELEEK---------------VKELKELKEKAEEYIK 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1322 IIEErnkdliikYNETREQLYRLEtekvERESTLRQLQQELADALKKLSMSEASLEVITRYRNDIEGEKQILQKEVEKFr 1401
Cdd:PRK03918 298 LSEF--------YEEYLDELREIE----KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELY- 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1402 ikvQDLEEQCNQAERLHHQLKNL--------LEDKEREVMAVSQKVQEYSSAAAGDENAIKELEGHVQKLEIENAKF--- 1470
Cdd:PRK03918 365 ---EEAKAKKEELERLKKRLTGLtpeklekeLEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCpvc 441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1471 --EATAKQQAGQIDILQKELRETLSIRHKLEELIASLQSSKMGLEEKLNHQvHKQTALSQSAQDSHNLwEEELKsrsrlG 1548
Cdd:PRK03918 442 grELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKE-SELIKLKELAEQLKEL-EEKLK-----K 514
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1549 IRLAELEHEKAEFAD-------------QVESEKKKVKKLIEHKRSMEARFDQEIKRNAELQRDISGLK-KLLKTAKKKI 1614
Cdd:PRK03918 515 YNLEELEKKAEEYEKlkekliklkgeikSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERL 594
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1615 KELESVGTQQSTQDGFKSTHFEKEIDIMKLKEKINELSFRLENESSNYKQLEAANRDLQQQLSSMKMFHKSQEHLEKGKR 1694
Cdd:PRK03918 595 KELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRE 674
|
570 580 590 600
....*....|....*....|....*....|....*....|
gi 1774923325 1695 ---------QLEDEVANLKRQIEINKVDQSLIEKHKREIE 1725
Cdd:PRK03918 675 laglraeleELEKRREEIKKTLEKLKEELEEREKAKKELE 714
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1125-1845 |
3.27e-08 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 59.08 E-value: 3.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1125 KLEHEKQGKDRLETELES----IRSRLTSTLQEVERNQALKIEVERTLQRERDEWLRSQDKLNHELSTIRENNNNLSQQL 1200
Cdd:pfam12128 245 KLQQEFNTLESAELRLSHlhfgYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSEL 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1201 ------------IRAETKSNSLENElrqtnTSLQDKVILSESTQRELTHTCGRIKELEHTLQLEKDKICKSTVkqESLQE 1268
Cdd:pfam12128 325 ealedqhgafldADIETAAADQEQL-----PSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDI--AGIKD 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1269 KLAQIQSENMLLRQQIEDVnnkgiiKDKTVSDVQDKFTEIIAKIRADAERQVQIIEERnKDLIIKYNETREQLYRLETEK 1348
Cdd:pfam12128 398 KLAKIREARDRQLAVAEDD------LQALESELREQLEAGKLEFNEEEYRLKSRLGEL-KLRLNQATATPELLLQLENFD 470
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1349 VErestLRQLQQELADALKKLSMSEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCN-QAERLHHQLKNLLED 1427
Cdd:pfam12128 471 ER----IERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFpQAGTLLHFLRKEAPD 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1428 KE--------REVMAVSQKVQEYSSAAAGDENAIKELEGHVQK------------LEIENAKFEATAKQQAGQIDILQKE 1487
Cdd:pfam12128 547 WEqsigkvisPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRidvpewaaseeeLRERLDKAEEALQSAREKQAAAEEQ 626
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1488 LretLSIRHKLEELIASLQSSKMGLE-----------EKLNHQVHKQTALS---QSAQDSHNLWEEELKSRSRlGIRLAe 1553
Cdd:pfam12128 627 L---VQANGELEKASREETFARTALKnarldlrrlfdEKQSEKDKKNKALAerkDSANERLNSLEAQLKQLDK-KHQAW- 701
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1554 LEHEKAEFADQVESEKKKVKKLIEHKRSMEARFDQEI-KRNAELQRDISGlkkllkTAKKKIKELESVGTQqstqdgfks 1632
Cdd:pfam12128 702 LEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIaARRSGAKAELKA------LETWYKRDLASLGVD--------- 766
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1633 thfekEIDIMKLKEKINELSFRLENESSNYKQLEAANRDLQQQLSSMKmfHKSQEHLEKGKRQLEDEVANLKRQIEINKV 1712
Cdd:pfam12128 767 -----PDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRR--PRLATQLSNIERAISELQQQLARLIADTKL 839
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1713 DQSLIEKhKREIEERGRLELKQKLEEVNLFLQSQAASQEtleqirAANDASVRNQMEHRIQELESDLGKIKNAQqenmlq 1792
Cdd:pfam12128 840 RRAKLEM-ERKASEKQQVRLSENLRGLRCEMSKLATLKE------DANSEQAQGSIGERLAQLEDLKLKRDYLS------ 906
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*.
gi 1774923325 1793 rESTQTELERFKELYNEelKNRNSLALKLERSNERLADANAK---LLNERQRTKSL 1845
Cdd:pfam12128 907 -ESVKKYVEHFKNVIAD--HSGSGLAETWESLREEDHYQNDKgirLLDYRKLVPYL 959
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
153-204 |
4.12e-08 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 51.19 E-value: 4.12e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1774923325 153 LLEHG-ANINAFNKEGCTPLILAVTENNEEMVEFLLKEGADINACDRGGRTSL 204
Cdd:pfam13857 1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTAL 53
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1538-1848 |
4.59e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 58.41 E-value: 4.59e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1538 EEELKSRSRLGIRLAELEHEKAEFADQVESEKKKVKKLIEHKRSMEARFDQEIKRNAELQRDISGLKKLLKTAKKKIKEL 1617
Cdd:COG1196 221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1618 ESvgtqqstqdgfksthfekeiDIMKLKEKINELSFRLENESSNYKQLEAANRDLQQQLssmkmfhksqEHLEKGKRQLE 1697
Cdd:COG1196 301 EQ--------------------DIARLEERRRELEERLEELEEELAELEEELEELEEEL----------EELEEELEEAE 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1698 DEVANLKRQIEinkvdQSLIEKHKREIEERGRLELKQKLEEVNLFLQSQAASQETLEQIRAANDASVRNQMEHRIQELES 1777
Cdd:COG1196 351 EELEEAEAELA-----EAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE 425
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1774923325 1778 DLGKIKNAQQENMLQRESTQTELERFKELYNEELKNRNSLAlKLERSNERLADANAKLLNERQRTKSLIAS 1848
Cdd:COG1196 426 LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA-ELLEEAALLEAALAELLEELAEAAARLLL 495
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
881-1593 |
4.98e-08 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 58.52 E-value: 4.98e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 881 KVKKMENEKKDLQQIAEKNRELKSMLDHQKVESESDLNSLRFTLKQEEEKRKnaemlygKSQEQLRRKEDQCCQ-EMEAK 959
Cdd:TIGR00606 399 VIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILE-------KKQEELKFVIKELQQlEGSSD 471
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 960 QLLELtirnlELEMRSMQNTVRQVEEERNeVQRLLSHEHNARIAQEDILNNIRRKSEEIENEKMWTKNAEVHGQLSKiDE 1039
Cdd:TIGR00606 472 RILEL-----DQELRKAERELSKAEKNSL-TETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTK-DK 544
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1040 REKDLILQNSNLQEEMNVLKLELDHvrsQNQQEESKYMDENENLKEKIADLRRDLKMNEETLTQTVIQYNSQLHALKTEN 1119
Cdd:TIGR00606 545 MDKDEQIRKIKSRHSDELTSLLGYF---PNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQL 621
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1120 TMLCSKLeHEKQGKDRLETELESIRSRLTSTLQE---VERNQALKIEVERTLQRERDEWLRSQDKLNHELSTIRENNNNL 1196
Cdd:TIGR00606 622 SSYEDKL-FDVCGSQDEESDLERLKEEIEKSSKQramLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDL 700
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1197 SQQLIRAETKSNSLENELRQTNTSLQDKVILSESTQRELTHTCGRIKELEHTLQLEKDKICKSTVKQESLQEKLAQIQSE 1276
Cdd:TIGR00606 701 QSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPE 780
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1277 NML-------------LRQQIEDVNNK---------GIIKDKTVSDVQDKFTEI---IAKIRADAERQVQIIEERNKDLI 1331
Cdd:TIGR00606 781 EESakvcltdvtimerFQMELKDVERKiaqqaaklqGSDLDRTVQQVNQEKQEKqheLDTVVSKIELNRKLIQDQQEQIQ 860
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1332 IKYNETREqlyrLETEKVERESTLRQLQQELADALKKLSMSEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQC 1411
Cdd:TIGR00606 861 HLKSKTNE----LKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSN 936
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1412 NQAERLHHQLKNLLEDKEREVMAVSQKVQEYSSAAAGD-ENAIKELEGHVQKLEIENAKFEATAKQQAGQID---ILQKE 1487
Cdd:TIGR00606 937 KKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQkETELNTVNAQLEECEKHQEKINEDMRLMRQDIDtqkIQERW 1016
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1488 LRETLSIRHKLEELIASLQSSKMGLEEKLNHQVHKQTALSQSAQDS-HNLWEEELKSRSRLGIRLAELEHEKAEFADQV- 1565
Cdd:TIGR00606 1017 LQDNLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENiDLIKRNHVLALGRQKGYEKEIKHFKKELREPQf 1096
|
730 740
....*....|....*....|....*....
gi 1774923325 1566 -ESEKKKVKKLIEHKRSMEARFDQEIKRN 1593
Cdd:TIGR00606 1097 rDAEEKYREMMIVMRTTELVNKDLDIYYK 1125
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1021-1621 |
5.49e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 58.15 E-value: 5.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1021 EKMWTKNAEVHGQLSKIDEREKDLILQNSNLQEEMNVLKLELDHVrsqnQQEESKYMDENENLKEKIADLRRDLKMNEET 1100
Cdd:PRK03918 161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEV----LREINEISSELPELREELEKLEKEVKELEEL 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1101 ltqtviqyNSQLHALKTENTMLCSKLEHEKQGKDRLETELESIRSRLTSTLQEVERNQALKIEVE--RTLQRERDEWLRS 1178
Cdd:PRK03918 237 --------KEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEeyIKLSEFYEEYLDE 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1179 QDKLNHELSTIRENNNNLSQQLIRAETKSNSLEnELRQTNTSLQDKVILSESTQRELThtcgRIKELEHTLQLEKDKICK 1258
Cdd:PRK03918 309 LREIEKRLSRLEEEINGIEERIKELEEKEERLE-ELKKKLKELEKRLEELEERHELYE----EAKAKKEELERLKKRLTG 383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1259 STVkqESLQEKLAQIQSENMLLRQQIEDVNNKgiiKDKTVSDVQDKFTEIIAKIRADAERQV---QIIEERNKDLIIKYn 1335
Cdd:PRK03918 384 LTP--EKLEKELEELEKAKEEIEEEISKITAR---IGELKKEIKELKKAIEELKKAKGKCPVcgrELTEEHRKELLEEY- 457
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1336 etREQLYRLETEKVERESTLRQLQQELADALKKLSMSEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAE 1415
Cdd:PRK03918 458 --TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLI 535
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1416 RLHHQLKNLLEDKEREvmavsqkvQEYSSAAAGDENAIKELEGHVQKL--EIENAKFEAtakqqagqIDILQKELRETLS 1493
Cdd:PRK03918 536 KLKGEIKSLKKELEKL--------EELKKKLAELEKKLDELEEELAELlkELEELGFES--------VEELEERLKELEP 599
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1494 IRHKLEELiaslQSSKMGLEEKLNHQVHKQTALSQSAQDshnlWEEELKSRSRLGIRLAELEHEKAEfaDQVESEKKKVK 1573
Cdd:PRK03918 600 FYNEYLEL----KDAEKELEREEKELKKLEEELDKAFEE----LAETEKRLEELRKELEELEKKYSE--EEYEELREEYL 669
|
570 580 590 600
....*....|....*....|....*....|....*....|....*...
gi 1774923325 1574 KLIEHKRSMEARFDQEIKRNAELQRDISGLKKLLKTAKKKIKELESVG 1621
Cdd:PRK03918 670 ELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLE 717
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
41-134 |
6.56e-08 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 57.60 E-value: 6.56e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 41 HRAASAGDVGKIKQLIKKQDINQLDKENRTPLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQESCATVL 120
Cdd:PTZ00322 88 QLAASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLL 167
|
90
....*....|....
gi 1774923325 121 LEHNADPNLVDING 134
Cdd:PTZ00322 168 SRHSQCHFELGANA 181
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
841-1276 |
6.94e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 57.82 E-value: 6.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 841 IEQLGVDSQDSVNLL------KFQNIIHEYERTIqreNGRYKLLASKVKKMENEKKDLQQIAEKNRELKSMLDHQKVESE 914
Cdd:pfam15921 247 LEALKSESQNKIELLlqqhqdRIEQLISEHEVEI---TGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLE 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 915 SDLNSLRFTLKQE----EEKRKNAE---MLYGKSQEQLRRKEDQCCQE------MEAKQLLELTIRNLELEMRSMQNTV- 980
Cdd:pfam15921 324 STVSQLRSELREAkrmyEDKIEELEkqlVLANSELTEARTERDQFSQEsgnlddQLQKLLADLHKREKELSLEKEQNKRl 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 981 ---------------RQVEEERNEVQRL------LSHEHNARIAQ----------------------EDILNNIRRKSEE 1017
Cdd:pfam15921 404 wdrdtgnsitidhlrRELDDRNMEVQRLeallkaMKSECQGQMERqmaaiqgkneslekvssltaqlESTKEMLRKVVEE 483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1018 IENEKMWTKNAE--VHGQLSKIDEREKDLILQNSNLQ----------EEMNVLKLELDHVRsqNQQEESKYMDENENLKE 1085
Cdd:pfam15921 484 LTAKKMTLESSErtVSDLTASLQEKERAIEATNAEITklrsrvdlklQELQHLKNEGDHLR--NVQTECEALKLQMAEKD 561
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1086 KIADLrrdLKMNEETLTQTVIQYNsqlhalKTENTMLCSKLEHEKQGKDR-LE-TELESIRSRLTSTLQEVE-RNQALKI 1162
Cdd:pfam15921 562 KVIEI---LRQQIENMTQLVGQHG------RTAGAMQVEKAQLEKEINDRrLElQEFKILKDKKDAKIRELEaRVSDLEL 632
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1163 E-------------VERTLQRERDEWLRSQDKLNHELSTIREN------------------NNNLSQQLIRAETKSNSLE 1211
Cdd:pfam15921 633 EkvklvnagserlrAVKDIKQERDQLLNEVKTSRNELNSLSEDyevlkrnfrnkseemettTNKLKMQLKSAQSELEQTR 712
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1774923325 1212 NELRQTNTSLQDKVILSESTQRELTHTCGRIKELEHTLQLEKDKICKSTVKQESLQEKLAQIQSE 1276
Cdd:pfam15921 713 NTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQE 777
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
68-121 |
1.32e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 49.97 E-value: 1.32e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1774923325 68 NRTPLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQESCATVLL 121
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1262-1475 |
1.41e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.93 E-value: 1.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1262 KQESLQEKLAQIQsenmllrQQIEDVNNKGIIKDKTVSDVQDKFTEIIAKIrADAERQVQIIEERnkdliikYNETREQL 1341
Cdd:COG4942 21 AAAEAEAELEQLQ-------QEIAELEKELAALKKEEKALLKQLAALERRI-AALARRIRALEQE-------LAALEAEL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1342 YRLETEKVERESTLRQLQQELADALKKLSMSEAS---------------------LEVITRYRND----IEGEKQILQKE 1396
Cdd:COG4942 86 AELEKEIAELRAELEAQKEELAELLRALYRLGRQpplalllspedfldavrrlqyLKYLAPARREqaeeLRADLAELAAL 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1774923325 1397 VEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEYSSAAAGDENAIKELEGHVQKLEIENAKFEATAK 1475
Cdd:COG4942 166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
40-88 |
1.54e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 49.58 E-value: 1.54e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1774923325 40 LHRAASAGDVGKIKQLI-KKQDINQLDKENRTPLHIACANGQLDTVKVLL 88
Cdd:pfam13637 5 LHAAAASGHLELLRLLLeKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
966-1328 |
2.87e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.84 E-value: 2.87e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 966 IRNLELEMRSMQNTVRQVEEERNEVQRLLSHEHnariaqedilnnirRKSEEIENEKmwtknAEVHGQLSKIDEREKDLI 1045
Cdd:TIGR02169 683 LEGLKRELSSLQSELRRIENRLDELSQELSDAS--------------RKIGEIEKEI-----EQLEQEEEKLKERLEELE 743
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1046 LQNSNLQEEMNVLKLELDHVRSQNQQEESKYmdenENLKEKIADLRRDLKMNEetltqtVIQYNSQLHALKTENTMLCSK 1125
Cdd:TIGR02169 744 EDLSSLEQEIENVKSELKELEARIEELEEDL----HKLEEALNDLEARLSHSR------IPEIQAELSKLEEEVSRIEAR 813
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1126 LEHEKQGKDRLETELESIRSRLTSTLQEVERNQALKIEVERT---LQRERDEWLRSQDKLNHELSTIRENNNNLSQQLIR 1202
Cdd:TIGR02169 814 LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEienLNGKKEELEEELEELEAALRDLESRLGDLKKERDE 893
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1203 AETKSNSLENELRQTNTSLQDKVILSESTQRELTHTCGRIKELEHTLQLEKDkICKSTVKQESLQEKLAQIQSENMLLrq 1282
Cdd:TIGR02169 894 LEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEE-IPEEELSLEDVQAELQRVEEEIRAL-- 970
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1774923325 1283 qiEDVNNKGIIKDKTVSDVQDKFTEIIAKIRADAERQVQIIEERNK 1328
Cdd:TIGR02169 971 --EPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1307-1845 |
3.69e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 55.46 E-value: 3.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1307 EIIAKIRADAERQVQIIEERNKDliiKYNETREQLYRLETEKVERESTLRQLQQELADALKKLSMSEASLEVITRYRNDI 1386
Cdd:PRK03918 136 EIDAILESDESREKVVRQILGLD---DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEI 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1387 EGEKQILQKEVEKFRIKVQDLEEqcnqaerlhhqLKNLLEDKEREVMAVSQKVQEYSSAAAGDENAIKELEGHVQKLEiE 1466
Cdd:PRK03918 213 SSELPELREELEKLEKEVKELEE-----------LKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE-E 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1467 NAKFEATAKQQAGQIDILQKELRETLSIRHKLEELIASLQSSKMGLEEKLnhqvhkqtalsQSAQDSHNLWEEELKSRSR 1546
Cdd:PRK03918 281 KVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERI-----------KELEEKEERLEELKKKLKE 349
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1547 LGIRLAELE--HEKAEFADQV--ESEKKKVKKLIEHKRSMEARFDQEIKRNAELQRDISGLKKLLKTAKKKIKELESVGT 1622
Cdd:PRK03918 350 LEKRLEELEerHELYEEAKAKkeELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIE 429
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1623 QQSTQDGfKSTHFEKEIDIMKLKEKINELSFRLENESSNYKQLEAANRDLQQQLSSMKMFHKSQEHLEKgKRQLEDEVAN 1702
Cdd:PRK03918 430 ELKKAKG-KCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIK-LKELAEQLKE 507
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1703 LKRqiEINKVDQSLIEKHKREIEErgrleLKQKLEEVNLflqsqaasqetlEQIRAANDASvrnqmehRIQELESDLGKI 1782
Cdd:PRK03918 508 LEE--KLKKYNLEELEKKAEEYEK-----LKEKLIKLKG------------EIKSLKKELE-------KLEELKKKLAEL 561
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1783 KNAQQENMLQRESTQTELERF---------------KELYNE-------------ELKNRNSLALKLERSNERLADANAK 1834
Cdd:PRK03918 562 EKKLDELEEELAELLKELEELgfesveeleerlkelEPFYNEylelkdaekelerEEKELKKLEEELDKAFEELAETEKR 641
|
570
....*....|.
gi 1774923325 1835 LLNERQRTKSL 1845
Cdd:PRK03918 642 LEELRKELEEL 652
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
1074-1828 |
4.10e-07 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 55.44 E-value: 4.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1074 SKYMDENENLKEKIADLRRDLKMNEETLtQTVIQYNSQLHALKTENTMLCSKLEHEKQGKDRLETELESIRSRLtstlQE 1153
Cdd:TIGR00606 182 TRYIKALETLRQVRQTQGQKVQEHQMEL-KYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRL----KE 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1154 VERNQALKIEVERTLQRERDEWLRSQdKLNHELSTIRENN-NNLSQQLIRAETKSNSLENELRQTNTSLQDKVILSESTQ 1232
Cdd:TIGR00606 257 IEHNLSKIMKLDNEIKALKSRKKQME-KDNSELELKMEKVfQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKER 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1233 RELTHTCGRIKELEHTLQLEKDKICKSTVKQESLQEKLA----------------QIQSENMLLRQQIEDvnnKGIIKDK 1296
Cdd:TIGR00606 336 RLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLAtrleldgfergpfserQIKNFHTLVIERQED---EAKTAAQ 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1297 TVSDVQDKFT---EIIAKIRADAERQVQIIEERNKDLIIKYNETREQLYRLETEKVERESTLrQLQQELADALKKLSMSE 1373
Cdd:TIGR00606 413 LCADLQSKERlkqEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRIL-ELDQELRKAERELSKAE 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1374 ASLEVITRYRNDIEgeKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDK---EREVMAVSQKVQEYSSAAAGDE 1450
Cdd:TIGR00606 492 KNSLTETLKKEVKS--LQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKmdkDEQIRKIKSRHSDELTSLLGYF 569
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1451 NAIKELEGHVQKLEIEnakfeatAKQQAGQIDILQKELRETLSIRHKLEELIASLQSSKMGLEEKLNHQVHKQTALSqsa 1530
Cdd:TIGR00606 570 PNKKQLEDWLHSKSKE-------INQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEES--- 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1531 qDSHNLWEEELKSRSRLGIrLAELEHEKAEFADQVESEKKKVKKLIehkrsmearfDQEIKRNAELQRDISGLKKLLKTA 1610
Cdd:TIGR00606 640 -DLERLKEEIEKSSKQRAM-LAGATAVYSQFITQLTDENQSCCPVC----------QRVFQTEAELQEFISDLQSKLRLA 707
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1611 KKKIKELESVGTQQSTQ--------DGFKSTHFEKEIDIMKLKEKINELSFRLENESSNY----KQLEAAN------RDL 1672
Cdd:TIGR00606 708 PDKLKSTESELKKKEKRrdemlglaPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIeeqeTLLGTIMpeeesaKVC 787
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1673 QQQLSSMKMFHKSQEHLEKGKRQLEDEVANLKRQIEINKVDQSLIEKHKREIEERGRLELKQKL----EEVNLFLQSQAA 1748
Cdd:TIGR00606 788 LTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLiqdqQEQIQHLKSKTN 867
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1749 SQETlEQIRAANDASVRNQMEHR----IQELESDLGKIKNAQQENMLQRESTQTELERFKELYNEELKNRNSLALKLERS 1824
Cdd:TIGR00606 868 ELKS-EKLQIGTNLQRRQQFEEQlvelSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDI 946
|
....
gi 1774923325 1825 NERL 1828
Cdd:TIGR00606 947 KEKV 950
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1450-1847 |
4.20e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.45 E-value: 4.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1450 ENAIKELEGHVQKL-----------EIENAKFEATAKQQAGQIDILQKELRETLSIRHKLEELIASLQSSKMGLEEKLNH 1518
Cdd:TIGR02168 192 EDILNELERQLKSLerqaekaerykELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEE 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1519 QVHKQTALSQSAQDSHNLWEEelksrsrLGIRLAELEHEKAEfadqvesekkkvkklieHKRSMEARFDQEIKRNAELQR 1598
Cdd:TIGR02168 272 LRLEVSELEEEIEELQKELYA-------LANEISRLEQQKQI-----------------LRERLANLERQLEELEAQLEE 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1599 DISGLKKLLKTAKKKIKELESvgtqqstqdgfksthfekeidimkLKEKINELSFRLENESSNYKQLEAANRDLQQQLss 1678
Cdd:TIGR02168 328 LESKLDELAEELAELEEKLEE------------------------LKEELESLEAELEELEAELEELESRLEELEEQL-- 381
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1679 mkmfhksqehlekgkRQLEDEVANLKRQIEINKVDQSLIEKHKREIEERgRLELKQKLEEVNlflqsqaasqetleqira 1758
Cdd:TIGR02168 382 ---------------ETLRSKVAQLELQIASLNNEIERLEARLERLEDR-RERLQQEIEELL------------------ 427
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1759 andasvRNQMEHRIQELESDLGKIKNAQQENMLQRESTQTELERFKELYNEELKNRNSLALKLERSNERLADANAKLLNE 1838
Cdd:TIGR02168 428 ------KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL 501
|
....*....
gi 1774923325 1839 RQRTKSLIA 1847
Cdd:TIGR02168 502 EGFSEGVKA 510
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
1134-1560 |
4.92e-07 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 54.30 E-value: 4.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1134 DRLEtELESIRSR-------LTSTLQEVERNQALKIEVERTLQRERDewlrSQDKLNHELStirennnNLSQQLIRAETK 1206
Cdd:pfam19220 17 DRLE-DLRSLKADfsqliepIEAILRELPQAKSRLLELEALLAQERA----AYGKLRRELA-------GLTRRLSAAEGE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1207 SNSLENELRQTNTSLQDkvilSESTQRELthtcgRIKELEHTLQLEkdkickstvkqeSLQEKLAQIQSENMLLRQQIED 1286
Cdd:pfam19220 85 LEELVARLAKLEAALRE----AEAAKEEL-----RIELRDKTAQAE------------ALERQLAAETEQNRALEEENKA 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1287 VNNKGIIKDKTVSDVQDKfteiiakiRADAERQVQIIEERNKDLIIKYNETREQLYRLETEKVERESTLRQLQQELADAL 1366
Cdd:pfam19220 144 LREEAQAAEKALQRAEGE--------LATARERLALLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALE 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1367 KKLSmseASLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEYSSAA 1446
Cdd:pfam19220 216 GQLA---AEQAERERAEAQLEEAVEAHRAERASLRMKLEALTARAAATEQLLAEARNQLRDRDEAIRAAERRLKEASIER 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1447 AGDENAIKELEGH-----VQKLEIENAKFEATAKQQAgqidiLQKELRETLSIRHKLEELIASLQSSKmgleEKLNHQVH 1521
Cdd:pfam19220 293 DTLERRLAGLEADlerrtQQFQEMQRARAELEERAEM-----LTKALAAKDAALERAEERIASLSDRI----AELTKRFE 363
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 1774923325 1522 KQ-TALSQSAqdshnlweEELKsrsrlgirlAELEHEKAE 1560
Cdd:pfam19220 364 VErAALEQAN--------RRLK---------EELQRERAE 386
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1302-1814 |
4.95e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 54.77 E-value: 4.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1302 QDKFTEIIAKIRADAERQVQIIEERNKDliikYNETREQLYRLETEKVERESTLRQLQQELADALKKLSMSEASLEvitr 1381
Cdd:COG4717 62 QGRKPELNLKELKELEEELKEAEEKEEE----YAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQE---- 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1382 yRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEYSSAAAGDenaIKELEGHVQ 1461
Cdd:COG4717 134 -LEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE---LEELQQRLA 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1462 KLEIENAKFEATAKQQAGQIDILQKELrETLSIRHKLEE-----LIASLQSSKMGLEEKLNHQVHKQTALSQSAQdSHNL 1536
Cdd:COG4717 210 ELEEELEEAQEELEELEEELEQLENEL-EAAALEERLKEarlllLIAAALLALLGLGGSLLSLILTIAGVLFLVL-GLLA 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1537 WEEELKSRSRlgirlAELEHEKAEFADQVESEKKKVKKLIEHKRSMEARFDQEIKRNAELQRDISGLKKLLKTAKKKIKE 1616
Cdd:COG4717 288 LLFLLLAREK-----ASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE 362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1617 LESVGTQQSTQDGFKSTHFEKEidimklkekiNELSFRLEnESSNYKQLEAANRDLQQQLSSMKMFHKSQEHLEkGKRQL 1696
Cdd:COG4717 363 LQLEELEQEIAALLAEAGVEDE----------EELRAALE-QAEEYQELKEELEELEEQLEELLGELEELLEAL-DEEEL 430
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1697 EDEVANLKRQIEinkvdqSLIEKHKREIEERGRLELKQKleevnlflqsQAASQETLEQIRaandasvrnqmeHRIQELE 1776
Cdd:COG4717 431 EEELEELEEELE------ELEEELEELREELAELEAELE----------QLEEDGELAELL------------QELEELK 482
|
490 500 510
....*....|....*....|....*....|....*...
gi 1774923325 1777 SDLGKIKNAQQENMLQRESTQTELERFKELYNEELKNR 1814
Cdd:COG4717 483 AELRELAEEWAALKLALELLEEAREEYREERLPPVLER 520
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
856-1328 |
5.22e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 55.07 E-value: 5.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 856 KFQNIIHEYERTIQRENGRYKLLASKVKKMENEKKDLQQIAEKNRELKSmLDHQKVESESDLNSLR-FTLKQEEEKRKNA 934
Cdd:PRK03918 294 EYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEE-LKKKLKELEKRLEELEeRHELYEEAKAKKE 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 935 EM------LYGKSQEQLRRKEDQCcqeMEAKQLLELTIRNLELEMRSMQNTVRQVEEERNEVQ----------RLLSHEH 998
Cdd:PRK03918 373 ELerlkkrLTGLTPEKLEKELEEL---EKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgRELTEEH 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 999 NARIAQEDI--LNNIRRKSEEIEN--EKMWTKNAEVHGQLSKIDE--REKDLILQNSNLQEEMNVLKLEldhvrsqnqqE 1072
Cdd:PRK03918 450 RKELLEEYTaeLKRIEKELKEIEEkeRKLRKELRELEKVLKKESEliKLKELAEQLKELEEKLKKYNLE----------E 519
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1073 ESKYMDENENLKEKIADLRRDLKMNEETLtqtviqynSQLHALKTENTMLCSKLEHEKQGKDRLETELE----SIRSRLT 1148
Cdd:PRK03918 520 LEKKAEEYEKLKEKLIKLKGEIKSLKKEL--------EKLEELKKKLAELEKKLDELEEELAELLKELEelgfESVEELE 591
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1149 STLQEVERNQALKIEVERTLQRERDEwLRSQDKLNHELSTIRENNNNLSQQLIRAETKSNSLEN--------ELRQTNTS 1220
Cdd:PRK03918 592 ERLKELEPFYNEYLELKDAEKELERE-EKELKKLEEELDKAFEELAETEKRLEELRKELEELEKkyseeeyeELREEYLE 670
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1221 LQDKVILSESTQRELTHTCGRIKELEHTLQLEKDKICKSTVKQESLQEKLAQIQSenmlLRQQIEDVNNKgiIKDKTVSD 1300
Cdd:PRK03918 671 LSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEE----LREKVKKYKAL--LKERALSK 744
|
490 500
....*....|....*....|....*...
gi 1774923325 1301 VQDKFTEIIAKIRADAERQVQIIEERNK 1328
Cdd:PRK03918 745 VGEIASEIFEELTEGKYSGVRVKAEENK 772
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
876-1221 |
5.22e-07 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 55.03 E-value: 5.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 876 KLLASKVKKMENEKKDLQQIAEKNRELKSMLDHQKVESESDLNSLRFTLKQEEEKRKNAEMLYGKSQEQLRRKEDQCCQE 955
Cdd:TIGR04523 296 EISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKL 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 956 MEAKQLLELTIRNLELEMRSMQNTVRQVEEERNEVQRLLsheHNARIAQEDILNNIRRKSEEIENEK-----MWTKNAEV 1030
Cdd:TIGR04523 376 KKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQI---KKLQQEKELLEKEIERLKETIIKNNseikdLTNQDSVK 452
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1031 HGQLSKIDEREKDLILQNSNLQEEMNVLKLELDHVRSQ---NQQEESKYMDENENLKEKIADLRRD---LKMNEETLTQT 1104
Cdd:TIGR04523 453 ELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKElksKEKELKKLNEEKKELEEKVKDLTKKissLKEKIEKLESE 532
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1105 VIQYNSQLHALKTE-----NTMLCSKLEHEKQGKDRLETELESIRSRLTSTLQEVERNQALKIEVERTLQRERDEWLRSQ 1179
Cdd:TIGR04523 533 KKEKESKISDLEDElnkddFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKI 612
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1774923325 1180 DKLNHELSTIRENNNNLSQQLIRAETKSNSLENELRQTNTSL 1221
Cdd:TIGR04523 613 SSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETI 654
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1055-1812 |
6.09e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 54.97 E-value: 6.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1055 MNVLKLEldhvrsQNQQEESKYMDENENLKEKIADLRRDLKMNEETLTQTVIQYNSQLHALKTENTMLCSKLEHEKQGKD 1134
Cdd:TIGR00618 170 MNLFPLD------QYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHA 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1135 RLETELESI--RSRLTSTLQEVER--NQALKIEVERTLQRERDEWLRSQDKLNHELSTIRENNNNLSQQLIRAETKSNSL 1210
Cdd:TIGR00618 244 YLTQKREAQeeQLKKQQLLKQLRAriEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSR 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1211 ENELRQTNTSLQDKVILSESTQrelthtcgrikeLEHTLQLEKDKICKSTVKQESLQEKLAQIQSENMLLRQQIEDvnnK 1290
Cdd:TIGR00618 324 AKLLMKRAAHVKQQSSIEEQRR------------LLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQ---K 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1291 GIIKDKTVSDVQDKFTEIIAKIRADAERQVQiieernkdliikyNETREQLYRLETEKVERESTLRQLQQELADALKKLS 1370
Cdd:TIGR00618 389 TTLTQKLQSLCKELDILQREQATIDTRTSAF-------------RDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEK 455
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1371 MSEASL-EVITRYRNDIEGE---KQILQKEVEKFRIKVQDL----EEQCNQAERLHH-----QLKNLLEDKEREVMAVSQ 1437
Cdd:TIGR00618 456 LEKIHLqESAQSLKEREQQLqtkEQIHLQETRKKAVVLARLlelqEEPCPLCGSCIHpnparQDIDNPGPLTRRMQRGEQ 535
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1438 KVQEYSSAAAGDENAIKELEGHVQKLEIENAKFEATAKQQAGQ-------IDILQKELRETLSIRHKLEELIASLQSSKM 1510
Cdd:TIGR00618 536 TYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCdnrskedIPNLQNITVRLQDLTEKLSEAEDMLACEQH 615
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1511 GLEEKLNHQVHKQtalsQSAQDSHNLWEEELKsrsrlgiRLAELEHEKAEFADQVESEKKKVKKLIEhKRSMEARFDQEI 1590
Cdd:TIGR00618 616 ALLRKLQPEQDLQ----DVRLHLQQCSQELAL-------KLTALHALQLTLTQERVREHALSIRVLP-KELLASRQLALQ 683
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1591 KRNAELQRDISGLKKLLKTAKKKIKELESVGTqqstqdgfksthfekeidimklkekinelSFRLENESSNykQLEAANR 1670
Cdd:TIGR00618 684 KMQSEKEQLTYWKEMLAQCQTLLRELETHIEE-----------------------------YDREFNEIEN--ASSSLGS 732
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1671 DLQQQLSSMKMFHKSQEHLEKGK---RQLEDEVANLKRQIEINKVDQslIEKHKREIEERGRL------ELKQKLEEVNL 1741
Cdd:TIGR00618 733 DLAAREDALNQSLKELMHQARTVlkaRTEAHFNNNEEVTAALQTGAE--LSHLAAEIQFFNRLreedthLLKTLEAEIGQ 810
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1774923325 1742 FLQSQAASQeTLEQIRAANDasvRNQMEHRIQELESDLGKIKNAQQENMLQRESTQTELERFKELYNEELK 1812
Cdd:TIGR00618 811 EIPSDEDIL-NLQCETLVQE---EEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDK 877
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
867-1464 |
6.85e-07 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 54.64 E-value: 6.85e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 867 TIQRENGRYKLLASKVKKMENEKKDLQQIAEKNRELKSMLDHQKVESESDLNslrfTLKQEEEKRKNaemlygksqeQLR 946
Cdd:TIGR04523 205 NLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLN----QLKDEQNKIKK----------QLS 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 947 RKEDQCCQEMEAKQLLELTIRNLELEMRSMQNtvRQVEEERNEVQrllshehnariaqeDILNNIRRKSEEIENEKMWTK 1026
Cdd:TIGR04523 271 EKQKELEQNNKKIKELEKQLNQLKSEISDLNN--QKEQDWNKELK--------------SELKNQEKKLEEIQNQISQNN 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1027 NA--EVHGQLSKIDEREKDLILQNSNLQEEMNVLKLELDHVRSQNQQeeskYMDENENLKEKIADLRRDLKMNEETLTQT 1104
Cdd:TIGR04523 335 KIisQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQS----YKQEIKNLESQINDLESKIQNQEKLNQQK 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1105 VIQYNsqlhalktentmlcsKLEHEKQGKDRLETELESIRSRLTSTLQEVERNQALKIEVERTLQRERDEWLRSQDKLNH 1184
Cdd:TIGR04523 411 DEQIK---------------KLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSR 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1185 ELSTIRENNNNLSQQLIRAETKSNSLENE---LRQTNTSLQDKVILSESTQRELThtcGRIKELEHTLQLEKDKICK--S 1259
Cdd:TIGR04523 476 SINKIKQNLEQKQKELKSKEKELKKLNEEkkeLEEKVKDLTKKISSLKEKIEKLE---SEKKEKESKISDLEDELNKddF 552
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1260 TVKQESLQEKLAQIQSENMLLRQQIEDVNNKGIIKDKTVSDVQDKFTEIIAKIR------ADAERQVQIIEERNKDLIIK 1333
Cdd:TIGR04523 553 ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEekekkiSSLEKELEKAKKENEKLSSI 632
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1334 YNETREQLYRLETEKVERESTLRQLQQELADALKKLSMSEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEeqcnq 1413
Cdd:TIGR04523 633 IKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIELMKDWLKELSLHYKKYITRMIRIKDLP----- 707
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 1774923325 1414 aerlhhqlknLLEDKEREVMAVSQKVQEYSsaaagdenaiKELEGHVQKLE 1464
Cdd:TIGR04523 708 ----------KLEEKYKEIEKELKKLDEFS----------KELENIIKNFN 738
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
850-1632 |
8.02e-07 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 54.46 E-value: 8.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 850 DSVNLLKFQNIIHEYERTIQRENGRYKLLAS------KVKKMENEKKDLQQI-AEKNRELKSMLDHQKVESESDLNSLRF 922
Cdd:pfam12128 229 DIQAIAGIMKIRPEFTKLQQEFNTLESAELRlshlhfGYKSDETLIASRQEErQETSAELNQLLRTLDDQWKEKRDELNG 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 923 TLKQEEEKRKNAEMLYGKSQEQLRRKEDQCCQEMEAKQLLELTIR----NLELEMRSMQNTVRQVEEERNEVQRLLSHEH 998
Cdd:pfam12128 309 ELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQseleNLEERLKALTGKHQDVTAKYNRRRSKIKEQN 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 999 NARIAQ-EDILNNIR----RKSEEIEN-----EKMWtkNAEVHGQLSKIDEREKDLILQNSNLQEEMN--------VLKL 1060
Cdd:pfam12128 389 NRDIAGiKDKLAKIReardRQLAVAEDdlqalESEL--REQLEAGKLEFNEEEYRLKSRLGELKLRLNqatatpelLLQL 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1061 ELDHV---RSQNQQEESKYMDENENLKEKIADLRRD----------LKMNE------ETLTQTVIQYNSQLHALKTE--- 1118
Cdd:pfam12128 467 ENFDErieRAREEQEAANAEVERLQSELRQARKRRDqasealrqasRRLEErqsaldELELQLFPQAGTLLHFLRKEapd 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1119 -----NTMLCSKLEH---------EKQGKDrlETELESIRSRLTS--TLQEVERNQALKIE---VERTLQRERDewlrSQ 1179
Cdd:pfam12128 547 weqsiGKVISPELLHrtdldpevwDGSVGG--ELNLYGVKLDLKRidVPEWAASEEELRERldkAEEALQSARE----KQ 620
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1180 DKLNHELSTIRENNNNLSQQLIRAETK-SNSLENELRQTNTSLQDKVILSESTQRELTHTCGRIKELEHTLQLEKDKIck 1258
Cdd:pfam12128 621 AAAEEQLVQANGELEKASREETFARTAlKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKH-- 698
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1259 stvkqeslQEKLAQIQSENMLLRQQIedvNNKGIIKDKTVSDVQDKFTEIIAKIRADAERQVQIIEERNKDLIIKYNETR 1338
Cdd:pfam12128 699 --------QAWLEEQKEQKREARTEK---QAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDP 767
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1339 EQLYRLETEkverestLRQLqqeladalkklsmsEASLEVITRYRNDIEGEKQILQkevEKFRIKVQDLEEQCNQAERLH 1418
Cdd:pfam12128 768 DVIAKLKRE-------IRTL--------------ERKIERIAVRRQEVLRYFDWYQ---ETWLQRRPRLATQLSNIERAI 823
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1419 HQLKNLLEDKEREVMAVSQKVQEYSSAAagdENAIKELEGHVQKLEIENAKFeATAKQQAgQIDILQKELRETLSirhKL 1498
Cdd:pfam12128 824 SELQQQLARLIADTKLRRAKLEMERKAS---EKQQVRLSENLRGLRCEMSKL-ATLKEDA-NSEQAQGSIGERLA---QL 895
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1499 EELIASLQSSKMGLEEKLNHQVHKQTALSQSAQDSHnlWE---EELKSRSRLGIRL----------AELEHEKAEFADQV 1565
Cdd:pfam12128 896 EDLKLKRDYLSESVKKYVEHFKNVIADHSGSGLAET--WEslrEEDHYQNDKGIRLldyrklvpylEQWFDVRVPQSIMV 973
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1774923325 1566 ESEKKK--VKKLIEHKRSMEArFDQEIKR-NAELQRDIS------GLKKLLKTAKKKIKELESVGTQQSTQDGFKS 1632
Cdd:pfam12128 974 LREQVSilGVDLTEFYDVLAD-FDRRIASfSRELQREVGeeaffeGVSESAVRIRSKVSELEYWPELRVFVKAFRL 1048
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
1028-1285 |
8.85e-07 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 54.15 E-value: 8.85e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1028 AEVHGQLSKIDEReKDLILQNSNLQeemnvlkleldhvrsQNQQEESKYMDENENLKEKIADLRRDLkmneETLTQTVIQ 1107
Cdd:PRK11281 39 ADVQAQLDALNKQ-KLLEAEDKLVQ---------------QDLEQTLALLDKIDRQKEETEQLKQQL----AQAPAKLRQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1108 YNSQLHALKTENTMLcSKLEHEKQGKDRLETELESIRSRLTS-------------TLQEV-ERNQ-ALKIEVERTLQrer 1172
Cdd:PRK11281 99 AQAELEALKDDNDEE-TRETLSTLSLRQLESRLAQTLDQLQNaqndlaeynsqlvSLQTQpERAQaALYANSQRLQQ--- 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1173 dewlrsqdkLNHELSTIRENNNNLS---QQLIRAETKSNSLENELRQT----NTSLQDkviLSEStQRELTHtcGRIKEL 1245
Cdd:PRK11281 175 ---------IRNLLKGGKVGGKALRpsqRVLLQAEQALLNAQNDLQRKslegNTQLQD---LLQK-QRDYLT--ARIQRL 239
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1774923325 1246 EHTLQLEKDKI-------CKSTVKQESLQEKLAQIQsENMLLRQQIE 1285
Cdd:PRK11281 240 EHQLQLLQEAInskrltlSEKTVQEAQSQDEAARIQ-ANPLVAQELE 285
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
120-174 |
1.13e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 47.34 E-value: 1.13e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1774923325 120 LLEH-NADPNLVDINGNAALHLAALIPSVSIAKQLLEHGANINAFNKEGCTPLILA 174
Cdd:pfam13857 1 LLEHgPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| TRPV |
cd21882 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ... |
46-188 |
1.27e-06 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily (TRPV), named after the vanilloid receptor 1 (TRPV1), consists of six members: four thermo-sensing channels (TRPV1, TRPV2, TRPV3, and TRPV4) and two Ca2+ selective channels (TRPV5 and TRPV6). The calcium-selective channels TRPV5 and TRPV6 can be heterotetramers and are important for general Ca2+ homeostasis. All four channels within the TRPV1-4 group show temperature-invoked currents when expressed in heterologous cell systems, ranging from activation at ~25C for TRPV4 to ~52C for TRPV2. The structure of TRPV shows the typical topology features of all Transient Receptor Potential (TRP) ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains. The TRP family consists of membrane proteins that function as ion channels that communicate between the cell and its environment, by a vast array of physical or chemical stimuli, including radiation (in the form of temperature, infrared ,or light) and pressure (osmotic or mechanical). TRP channels are formed by a tetrameric complex of channel subunits. Based on sequence identity, the mammalian TRP channel family is classified into six subfamilies, with significant sequence similarity within the transmembrane domains, but very low similarity in their N- and C-terminal cytoplasmic regions. The six subfamilies are named based on their first member: TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPA (ankyrin), TRPML (mucolipin), and TRPP (polycystic).
Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 53.35 E-value: 1.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 46 AGDVGKIKQLIKKQDINQLdKENRTPLHIACANGQLDTVKVLLEHKSKLNLCDNDN---RS----------PLLKAIQCQ 112
Cdd:cd21882 52 APDSGNPKELVNAPCTDEF-YQGQTALHIAIENRNLNLVRLLVENGADVSARATGRffrKSpgnlfyfgelPLSLAACTN 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 113 QESCATVLLEHNADP---NLVDINGNAALHLAALIPS---------VSIAKQLLEHGANINAF-------NKEGCTPLIL 173
Cdd:cd21882 131 QEEIVRLLLENGAQPaalEAQDSLGNTVLHALVLQADntpensafvCQMYNLLLSYGAHLDPTqqleeipNHQGLTPLKL 210
|
170
....*....|....*
gi 1774923325 174 AVTENNEEMVEFLLK 188
Cdd:cd21882 211 AAVEGKIVMFQHILQ 225
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
146-267 |
1.28e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 53.13 E-value: 1.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 146 SVSIAKQLLEHGANINAFNKEGCTPLILAVTENNEEMVEFLLKEGADINACDRGGRTSLMISSNNGQN-----NLVRILL 220
Cdd:PHA03100 14 KVKNIKYIIMEDDLNDYSYKKPVLPLYLAKEARNIDVVKILLDNGADINSSTKNNSTPLHYLSNIKYNltdvkEIVKLLL 93
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1774923325 221 QNEADINIKDEKSWTADDYGVMNghHACSHLIIEHGSKKRVNMSPCY 267
Cdd:PHA03100 94 EYGANVNAPDNNGITPLLYAISK--KSNSYSIVEYLLDNGANVNIKN 138
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
60-108 |
1.38e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 46.96 E-value: 1.38e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1774923325 60 DINQLDKENRTPLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKA 108
Cdd:pfam13857 8 DLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
894-1417 |
1.42e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 53.51 E-value: 1.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 894 QIAEK-NRELKSMLDhqkvESESDLNSLRFTLKQEEEKRKNAEMLYGKSQEQLRRKEdqccQEMEAKQLLELTIRNLEL- 971
Cdd:PRK02224 195 QIEEKeEKDLHERLN----GLESELAELDEEIERYEEQREQARETRDEADEVLEEHE----ERREELETLEAEIEDLREt 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 972 -------------EMRSMQNTVRQVEEERNEVQRLLSHEHNARIAQEDILNNIRRKSEEIENEKMWTKNA--EVHGQLSK 1036
Cdd:PRK02224 267 iaeterereelaeEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAaqAHNEEAES 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1037 IDEREKDLILQNSNLQEEMNVLKLELDHVRS-----QNQQEE-SKYMDENE-------------------------NLKE 1085
Cdd:PRK02224 347 LREDADDLEERAEELREEAAELESELEEAREavedrREEIEElEEEIEELRerfgdapvdlgnaedfleelreerdELRE 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1086 KIADLRRDLKMNEETLTQtviqyNSQLHAL--------KTENTMLCSKLEHEKQGKDRLETELESIRSRLTSTLQEVERN 1157
Cdd:PRK02224 427 REAELEATLRTARERVEE-----AEALLEAgkcpecgqPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERA 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1158 QALKiEVERTLQRERDEWLRSQDKLNHELSTIRENNNNLSQQLIRAEtksnSLENELRQTNTSLQDKVILSESTQRElth 1237
Cdd:PRK02224 502 EDLV-EAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAA----ELEAEAEEKREAAAEAEEEAEEAREE--- 573
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1238 tcgrIKELEHTLQLEKDKIckstvkqESLqEKLAQIQSENMLLRQQIEDVNNKgiikdktVSDVQDKFTEIIAKIRADAE 1317
Cdd:PRK02224 574 ----VAELNSKLAELKERI-------ESL-ERIRTLLAAIADAEDEIERLREK-------REALAELNDERRERLAEKRE 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1318 RQVQIIEERNKDLIikyNETREQLYRLETEKVERESTLRQLQQELADALKKLSMSEASLEvitryrndiegEKQILQKEV 1397
Cdd:PRK02224 635 RKRELEAEFDEARI---EEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELE-----------ELEELRERR 700
|
570 580
....*....|....*....|
gi 1774923325 1398 EKFRIKVQDLEEQCNQAERL 1417
Cdd:PRK02224 701 EALENRVEALEALYDEAEEL 720
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
879-1533 |
1.53e-06 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 53.57 E-value: 1.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 879 ASKVKKME-NEKKDLQQIAEKNRELKSMLDHQ-KVESESDLNSLRFTLKQEEEKRKNAEMLygkSQEQLRRKEDQCCQEM 956
Cdd:pfam05483 87 AEKIKKWKvSIEAELKQKENKLQENRKIIEAQrKAIQELQFENEKVSLKLEEEIQENKDLI---KENNATRHLCNLLKET 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 957 EAKQLLELTIRNLELEmrsmqnTVRQVEEE-RNEVQRLLSHEHNARIAQEDILNNIRRKSEEiENEKMWTKNAEVHGQLS 1035
Cdd:pfam05483 164 CARSAEKTKKYEYERE------ETRQVYMDlNNNIEKMILAFEELRVQAENARLEMHFKLKE-DHEKIQHLEEEYKKEIN 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1036 KIDEREKDLILQNSNLQEEMNVLKLELDHVRSQNQQEESKYMDENENLKEKIAD------------------------LR 1091
Cdd:pfam05483 237 DKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKkdhltkeledikmslqrsmstqkaLE 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1092 RDLKMNEETLTQTVIQYNSQLHAL---KTENTMLCSKLE-----------HEKQGKDRLETELESIRSRLTSTLQEVER- 1156
Cdd:pfam05483 317 EDLQIATKTICQLTEEKEAQMEELnkaKAAHSFVVTEFEattcsleellrTEQQRLEKNEDQLKIITMELQKKSSELEEm 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1157 -----NQALKIEVERTLQRERDEWLRSQDKLNHELSTIRENNNNLSQQLIRAETKSNSLENELRQTNTSLQdkvilsest 1231
Cdd:pfam05483 397 tkfknNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEE--------- 467
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1232 qreltHTCGRIKELEHTLQLEKDKICKSTVKQESL---QEKLAQIQSENML-LRQQIEDVNNKGIIKDKTVSDVQDkFTE 1307
Cdd:pfam05483 468 -----HYLKEVEDLKTELEKEKLKNIELTAHCDKLlleNKELTQEASDMTLeLKKHQEDIINCKKQEERMLKQIEN-LEE 541
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1308 IIAKIRADAERQVQIIEERNKDLIIKYNETREQLYRLETEKVERESTLRQLQQELADALKKLSMSEASLEVITRYRNDIE 1387
Cdd:pfam05483 542 KEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALK 621
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1388 GEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEdKEREVMAVSQK--VQEYSSAAAGDENAIK----------- 1454
Cdd:pfam05483 622 KKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQ-KEIEDKKISEEklLEEVEKAKAIADEAVKlqkeidkrcqh 700
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1774923325 1455 ELEGHVQKLEIENAKFEATAKQQAGQIDILQKELRETLSIRHKLEELIASLQSSKMGLEEKLNHQVHKQTALSQSAQDS 1533
Cdd:pfam05483 701 KIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKEN 779
|
|
| TRPV |
cd21882 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ... |
69-223 |
1.63e-06 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily (TRPV), named after the vanilloid receptor 1 (TRPV1), consists of six members: four thermo-sensing channels (TRPV1, TRPV2, TRPV3, and TRPV4) and two Ca2+ selective channels (TRPV5 and TRPV6). The calcium-selective channels TRPV5 and TRPV6 can be heterotetramers and are important for general Ca2+ homeostasis. All four channels within the TRPV1-4 group show temperature-invoked currents when expressed in heterologous cell systems, ranging from activation at ~25C for TRPV4 to ~52C for TRPV2. The structure of TRPV shows the typical topology features of all Transient Receptor Potential (TRP) ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains. The TRP family consists of membrane proteins that function as ion channels that communicate between the cell and its environment, by a vast array of physical or chemical stimuli, including radiation (in the form of temperature, infrared ,or light) and pressure (osmotic or mechanical). TRP channels are formed by a tetrameric complex of channel subunits. Based on sequence identity, the mammalian TRP channel family is classified into six subfamilies, with significant sequence similarity within the transmembrane domains, but very low similarity in their N- and C-terminal cytoplasmic regions. The six subfamilies are named based on their first member: TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPA (ankyrin), TRPML (mucolipin), and TRPP (polycystic).
Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 52.96 E-value: 1.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 69 RTPLHIACAN---GQLDTVKVLLEHKSklnlcDNDNRSPLLKaiqcqqESCATVLLEhnadpnlvdinGNAALHLAALIP 145
Cdd:cd21882 27 KTCLHKAALNlndGVNEAIMLLLEAAP-----DSGNPKELVN------APCTDEFYQ-----------GQTALHIAIENR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 146 SVSIAKQLLEHGANINA------FNKEGCT-------PLILAVTENNEEMVEFLLKEGADI---NACDRGGRTSL----M 205
Cdd:cd21882 85 NLNLVRLLVENGADVSAratgrfFRKSPGNlfyfgelPLSLAACTNQEEIVRLLLENGAQPaalEAQDSLGNTVLhalvL 164
|
170
....*....|....*...
gi 1774923325 206 ISSNNGQNNLVRILLQNE 223
Cdd:cd21882 165 QADNTPENSAFVCQMYNL 182
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1067-1360 |
1.64e-06 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 53.20 E-value: 1.64e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1067 SQNQQEESKYMDENENLK----EKIADLRRDLKMNE-ETLTQTVIQYNSQLHAlktentmlcsklEHEKQGKDRlETELE 1141
Cdd:pfam17380 285 SERQQQEKFEKMEQERLRqekeEKAREVERRRKLEEaEKARQAEMDRQAAIYA------------EQERMAMER-ERELE 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1142 SIRSRLTSTLQEVERNQALKIEVERTLQRERDEWLRSQ--DKLNHELSTIRENNNNLSQQLIRAETKSNSLENELRQTNT 1219
Cdd:pfam17380 352 RIRQEERKRELERIRQEEIAMEISRMRELERLQMERQQknERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEE 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1220 SLQDKV-ILSESTQRELTHTcgRIKELEHTLQLEKDKICKSTVKQESL-----QEKLAQIQSEN-MLLRQQIE------- 1285
Cdd:pfam17380 432 ARQREVrRLEEERAREMERV--RLEEQERQQQVERLRQQEEERKRKKLelekeKRDRKRAEEQRrKILEKELEerkqami 509
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1774923325 1286 DVNNKGIIKDKTVSDVQDKFTEIIAKIRADAERQVQIIEERNKDLIIKYNETREQLYRLETEKVEREsTLRQLQQ 1360
Cdd:pfam17380 510 EEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMERERE-MMRQIVE 583
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
186-239 |
2.32e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 46.57 E-value: 2.32e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1774923325 186 LLKEG-ADINACDRGGRTSLMISSNNGQNNLVRILLQNEADINIKDEKSWTADDY 239
Cdd:pfam13857 1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDL 55
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
166-198 |
2.77e-06 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 45.36 E-value: 2.77e-06
10 20 30
....*....|....*....|....*....|....
gi 1774923325 166 EGCTPLILAVTE-NNEEMVEFLLKEGADINACDR 198
Cdd:pfam00023 1 DGNTPLHLAAGRrGNLEIVKLLLSKGADVNARDK 34
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
103-246 |
3.14e-06 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 52.56 E-value: 3.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 103 SPLLKAIQCQQESCATVL---LEHNADpnLVDINGNAALhlaalipsvsiAKQLLEHGANINAFNkegctpLILAVTENN 179
Cdd:PLN03192 477 STLIEAMQTRQEDNVVILknfLQHHKE--LHDLNVGDLL-----------GDNGGEHDDPNMASN------LLTVASTGN 537
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1774923325 180 EEMVEFLLKEGADINACDRGGRTSLMISSNNGQNNLVRILLQNEADINIKDEKSWTADDYGVMNGHH 246
Cdd:PLN03192 538 AALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHH 604
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1319-1528 |
3.71e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.30 E-value: 3.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1319 QVQIIEERNKDLIIKYNETREQLYRLETEKVERESTLRQLQ---QELADALKKLSMSEASLEVITRYRNDIEGEKQILQK 1395
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAaleRRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1396 EVEKFRikvQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEYSSAAAGDENAIKELEGHVQKLEIENAKFEATAK 1475
Cdd:COG4942 98 ELEAQK---EELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1774923325 1476 QQAGQIDILQKELRETLSIRHKLEELIASLQSSKMGLEEKLNHQVHKQTALSQ 1528
Cdd:COG4942 175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
169-220 |
4.88e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 45.34 E-value: 4.88e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1774923325 169 TPLILAVTENNEEMVEFLLKEGADINACDRGGRTSLMISSNNGQNNLVRILL 220
Cdd:pfam13637 3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
53-230 |
5.93e-06 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 51.17 E-value: 5.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 53 KQLIKKQDINQLDKENRTPLHIACANGQLDTVKVLLEHKSklnlCDNDNRSPLlkaiqcqqescatvllehnadpnlvdi 132
Cdd:cd22192 2 AQMLDELHLLQQKRISESPLLLAAKENDVQAIKKLLKCPS----CDLFQRGAL--------------------------- 50
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 133 nGNAALHLAALIPSVSIAKQLLEhGANINAFNK------EGCTPLILAVTENNEEMVEFLLKEGADIN------ACDRGG 200
Cdd:cd22192 51 -GETALHVAALYDNLEAAVVLME-AAPELVNEPmtsdlyQGETALHIAVVNQNLNLVRELIARGADVVspratgTFFRPG 128
|
170 180 190
....*....|....*....|....*....|....*...
gi 1774923325 201 RTSLM--------ISSNNGQNNLVRILLQNEADINIKD 230
Cdd:cd22192 129 PKNLIyygehplsFAACVGNEEIVRLLIEHGADIRAQD 166
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1259-1557 |
6.44e-06 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 51.17 E-value: 6.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1259 STVKQESLQEKLAQIQSEnMLLRQQIEDVNnkgiiKDKTVSDVQDKFTEIIAKIRadaeRQVQIIEERNKDLI-IKYNET 1337
Cdd:COG3206 76 LSASDSPLETQIEILKSR-PVLERVVDKLN-----LDEDPLGEEASREAAIERLR----KNLTVEPVKGSNVIeISYTSP 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1338 REQL--------------YRLETEKVERESTLRQLQQELADALKKLSMSEASLEvitRYRN-----DIEGEKQILQKEVE 1398
Cdd:COG3206 146 DPELaaavanalaeayleQNLELRREEARKALEFLEEQLPELRKELEEAEAALE---EFRQknglvDLSEEAKLLLQQLS 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1399 KFRIKVQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQkvqeyssaaagdENAIKELEGHVQKLEIENAKFEATAKQQA 1478
Cdd:COG3206 223 ELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQ------------SPVIQQLRAQLAELEAELAELSARYTPNH 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1479 GQIDILQKELRETLS-IRHKLEELIASLQSSKMGLEEKLNhqvhkqtALSQSAQDShnlwEEELKSRSRLGIRLAELEHE 1557
Cdd:COG3206 291 PDVIALRAQIAALRAqLQQEAQRILASLEAELEALQAREA-------SLQAQLAQL----EARLAELPELEAELRRLERE 359
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
166-195 |
9.40e-06 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 44.12 E-value: 9.40e-06
10 20 30
....*....|....*....|....*....|
gi 1774923325 166 EGCTPLILAVTENNEEMVEFLLKEGADINA 195
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
860-1134 |
1.09e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 50.51 E-value: 1.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 860 IIHEYERTIQRENGRYKLLASKVKKMENEKKDLQQIA---EKNRELKSMLDHQKVESESDLNSL----RFTLKQEEEKRK 932
Cdd:pfam17380 335 IYAEQERMAMERERELERIRQEERKRELERIRQEEIAmeiSRMRELERLQMERQQKNERVRQELeaarKVKILEEERQRK 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 933 NAEMLYG-----KSQEQLRRKEDQCCQEMEAKQLLEltIRNLELEMRSMQNTVRQVEEERNEVQRLLSHEhnariaqedi 1007
Cdd:pfam17380 415 IQQQKVEmeqirAEQEEARQREVRRLEEERAREMER--VRLEEQERQQQVERLRQQEEERKRKKLELEKE---------- 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1008 lnniRRKSEEIENEKMWTKNAEVHGQLSKIDEREKDLILQNSNLQEEMNVLKLELDHVRSQNQQEESKYMDENENLKEKI 1087
Cdd:pfam17380 483 ----KRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQM 558
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1774923325 1088 adlrrdLKMNEEtltqtviqyNSQLHALKTENTMLCSKLEHEKQGKD 1134
Cdd:pfam17380 559 ------RKATEE---------RSRLEAMEREREMMRQIVESEKARAE 590
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1353-1567 |
1.33e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.76 E-value: 1.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1353 STLRQLQQELADALKKLSMSEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKEREV 1432
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1433 MAVSQKVQEYSSAA--AGDENAIKEL--EGHVQKLEIENAKFEATAKQQAGQIDILQKELRETLSIRHKLEELIASLQSS 1508
Cdd:COG4942 100 EAQKEELAELLRALyrLGRQPPLALLlsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1774923325 1509 KMGLEE---KLNHQVHKQTALSQSAQDSHNLWEEEL----KSRSRLGIRLAELEHEKAEFADQVES 1567
Cdd:COG4942 180 LAELEEeraALEALKAERQKLLARLEKELAELAAELaelqQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| trp |
TIGR00870 |
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ... |
42-224 |
1.35e-05 |
|
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 50.08 E-value: 1.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 42 RAASAGDVGKIKQLI---KKQDINQLDKENRTPL-HIACANGQLDTVKVLLEHKSKLNLCDNdnrspLLKAI----QCQQ 113
Cdd:TIGR00870 23 PAAERGDLASVYRDLeepKKLNINCPDRLGRSALfVAAIENENLELTELLLNLSCRGAVGDT-----LLHAIsleyVDAV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 114 ESCATVLLEHNAD----PNLVDINGN------AALHLAALIPSVSIAKQLLEHGANINAFNK--------------EGCT 169
Cdd:TIGR00870 98 EAILLHLLAAFRKsgplELANDQYTSeftpgiTALHLAAHRQNYEIVKLLLERGASVPARACgdffvksqgvdsfyHGES 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1774923325 170 PLILAVTENNEEMVEFLLKEGADINACDRGGRT----SLMISSNNGQNNLVRILLQNEA 224
Cdd:TIGR00870 178 PLNAAACLGSPSIVALLSEDPADILTADSLGNTllhlLVMENEFKAEYEELSCQMYNFA 236
|
|
| PHA02946 |
PHA02946 |
ankyin-like protein; Provisional |
72-204 |
1.40e-05 |
|
ankyin-like protein; Provisional
Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 49.67 E-value: 1.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 72 LHIACANGQLDT--VKVLLEHKSKLNLCDNDNRSPLLKAIQCQQESCATVLLEHNADPNLVDINGNAALHLAALIPSVSI 149
Cdd:PHA02946 41 LHAYCGIKGLDErfVEELLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLYYLSGTDDEVI 120
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1774923325 150 AK--QLLEHGANI-NAFNKEGCTPLiLAVTENNEEMVEFLLKEGADINACDRGGRTSL 204
Cdd:PHA02946 121 ERinLLVQYGAKInNSVDEEGCGPL-LACTDPSERVFKKIMSIGFEARIVDKFGKNHI 177
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
855-1597 |
1.51e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 50.34 E-value: 1.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 855 LKFQNIIHEYERTIQRENGRYKLLASKVKKMENEKKDLQQiaeknrELKSMLDHQ-----------KVES-ESDLNSLRF 922
Cdd:PRK04863 289 LELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQ------DYQAASDHLnlvqtalrqqeKIERyQADLEELEE 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 923 TLKQEEEKRKNAEMLYGKSQEQLRRKEDQ---------------------CCQEMEAKQLLE----------LTIRNLEL 971
Cdd:PRK04863 363 RLEEQNEVVEEADEQQEENEARAEAAEEEvdelksqladyqqaldvqqtrAIQYQQAVQALErakqlcglpdLTADNAED 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 972 EMRSMQNTVRQVEEERNEVQRLLSHEHNARIAQEDILNNIRRKSEEIENEKMWTKNAEVHGQLSkiderekdlilqnsnl 1051
Cdd:PRK04863 443 WLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEAWDVARELLRRLR---------------- 506
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1052 qeemnvlklELDHVRSQNQQeeskymdenenLKEKIADLRRDLKmNEETLTQTVIQYNSQLHALKTENTMLCSKLEHEKQ 1131
Cdd:PRK04863 507 ---------EQRHLAEQLQQ-----------LRMRLSELEQRLR-QQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEA 565
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1132 GKDRLETELESIRSRLTSTLQEVErnqALKIEVERtLQRERDEWLRSQDKLNHeLSTIRENNNNLSQQLIraETKSNSLE 1211
Cdd:PRK04863 566 RLESLSESVSEARERRMALRQQLE---QLQARIQR-LAARAPAWLAAQDALAR-LREQSGEEFEDSQDVT--EYMQQLLE 638
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1212 NElrqtnTSLQDKVILSESTQRELThtcGRIKELEH--TLQLEKDKICKSTVKQESLQEKLAQIQSEN------ML--LR 1281
Cdd:PRK04863 639 RE-----RELTVERDELAARKQALD---EEIERLSQpgGSEDPRLNALAERFGGVLLSEIYDDVSLEDapyfsaLYgpAR 710
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1282 QQIEdVNNKGIIKDKTVSdvQDKFTEIIAKIRADAER---QVQIIEERNKDLIIKYN-----------------ETREQl 1341
Cdd:PRK04863 711 HAIV-VPDLSDAAEQLAG--LEDCPEDLYLIEGDPDSfddSVFSVEELEKAVVVKIAdrqwrysrfpevplfgrAAREK- 786
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1342 yRLETEKVERESTLR---------QLQQELADALKK-----LSMS-----EASLEVITRYRNDIEGEKQILQKEVEKFRI 1402
Cdd:PRK04863 787 -RIEQLRAEREELAEryatlsfdvQKLQRLHQAFSRfigshLAVAfeadpEAELRQLNRRRVELERALADHESQEQQQRS 865
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1403 KVQDLEEQCNQAERLHHQLKNLLEDK-EREVMAVSQKVQEYSSAAAgdenAIKELEGHVQKLEienaKFEATAKQQAGQI 1481
Cdd:PRK04863 866 QLEQAKEGLSALNRLLPRLNLLADETlADRVEEIREQLDEAEEAKR----FVQQHGNALAQLE----PIVSVLQSDPEQF 937
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1482 DILQKElretlsirhkLEELIASLQSSKMGLEEkLNHQVHKQTALSQSaqDSHNLWEEELKSRSRLGIRLAELEHEKAEF 1561
Cdd:PRK04863 938 EQLKQD----------YQQAQQTQRDAKQQAFA-LTEVVQRRAHFSYE--DAAEMLAKNSDLNEKLRQRLEQAEQERTRA 1004
|
810 820 830
....*....|....*....|....*....|....*.
gi 1774923325 1562 ADQVesekkkvkkliehkRSMEARFDQEIKRNAELQ 1597
Cdd:PRK04863 1005 REQL--------------RQAQAQLAQYNQVLASLK 1026
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
1352-1708 |
1.68e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 49.51 E-value: 1.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1352 ESTLRQLQQELADALKKLsmsEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKERE 1431
Cdd:pfam07888 33 QNRLEECLQERAELLQAQ---EAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSAS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1432 VMAVSQKVQEYSSAAAGDENAIKELEGHVQKL-------EIENAKFEATAKQQAGQidiLQKELRETLSIRHKLEELIAS 1504
Cdd:pfam07888 110 SEELSEEKDALLAQRAAHEARIRELEEDIKTLtqrvlerETELERMKERAKKAGAQ---RKEEEAERKQLQAKLQQTEEE 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1505 LQSSKMGLEEKLNHQVHKQTALSQsAQDSHNLWEEELKSRSRlgiRLAELEHEKAEFA---DQVESEKKKVKKLIEHKRS 1581
Cdd:pfam07888 187 LRSLSKEFQELRNSLAQRDTQVLQ-LQDTITTLTQKLTTAHR---KEAENEALLEELRslqERLNASERKVEGLGEELSS 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1582 MEARFDQEIkrnAELQRDISGLKKLLKTAKKKIKEL-ESVGT-QQSTQDGFKSTHFEKEiDIMKLKEKINELSFRLENE- 1658
Cdd:pfam07888 263 MAAQRDRTQ---AELHQARLQAAQLTLQLADASLALrEGRARwAQERETLQQSAEADKD-RIEKLSAELQRLEERLQEEr 338
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1774923325 1659 --------------SSNYKQLEAANRDLQQQLSSMKMFHKSQEHLEKGKRQLEDEVANLKRQIE 1708
Cdd:pfam07888 339 mereklevelgrekDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLE 402
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
901-1211 |
1.92e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 49.74 E-value: 1.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 901 ELKSMLDHQKVESEsdlnslrftlKQEEEKRKNAEmlygksQEQLRRKEDQCCQEMEAKQLLE--LTIRNLELEMRSM-- 976
Cdd:pfam17380 273 QLLHIVQHQKAVSE----------RQQQEKFEKME------QERLRQEKEEKAREVERRRKLEeaEKARQAEMDRQAAiy 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 977 QNTVRQVEEERNEVQRLLSHE---HNARIAQEDILNNIRRkSEEIENEKM--WTKNAEVHGQLS-----KIDEREKDLIL 1046
Cdd:pfam17380 337 AEQERMAMERERELERIRQEErkrELERIRQEEIAMEISR-MRELERLQMerQQKNERVRQELEaarkvKILEEERQRKI 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1047 QNSNL-------------QEEMNVLKLELDHVRSQNQQEESKYMDENENLKEKIADLRR-DLKMNEETLTQTVIQYNSQL 1112
Cdd:pfam17380 416 QQQKVemeqiraeqeearQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRkKLELEKEKRDRKRAEEQRRK 495
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1113 hALKTENTMLCSKLEHEKQGKDRLETELEsirSRLTSTLQEVERNQAlkiEVERTLQRERDEWLRSQD---KLNHELSTI 1189
Cdd:pfam17380 496 -ILEKELEERKQAMIEEERKRKLLEKEME---ERQKAIYEEERRREA---EEERRKQQEMEERRRIQEqmrKATEERSRL 568
|
330 340
....*....|....*....|....
gi 1774923325 1190 R--ENNNNLSQQLIRAETKSNSLE 1211
Cdd:pfam17380 569 EamEREREMMRQIVESEKARAEYE 592
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
966-1457 |
2.34e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.38 E-value: 2.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 966 IRNLELEMRSMQNTVRQVEEERNEVQRLLSHEHNARIAQEDILNNIRRKSEEIENEKMWTKNAEvhgqlskiderekdli 1045
Cdd:COG4717 73 LKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEA---------------- 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1046 lqnsnLQEEMNVLKLELDHVRSQNQQEESKyMDENENLKEKIADLRRDLkmnEETLTQTVIQYNSQLHALKTENTMLCSK 1125
Cdd:COG4717 137 -----LEAELAELPERLEELEERLEELREL-EEELEELEAELAELQEEL---EELLEQLSLATEEELQDLAEELEELQQR 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1126 LEHEKQGKDRLETELESIRSRLTSTLQEVERNQAlkievERTLQRERDEWLRsqdklnhelstirennnnLSQQLIRAET 1205
Cdd:COG4717 208 LAELEEELEEAQEELEELEEELEQLENELEAAAL-----EERLKEARLLLLI------------------AAALLALLGL 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1206 KSNSLENELRQTN---TSLQDKVILSESTQRELTHTCGRIKELEHTLQLEKdkickstVKQESLQEKLAQIQSENMLLRQ 1282
Cdd:COG4717 265 GGSLLSLILTIAGvlfLVLGLLALLFLLLAREKASLGKEAEELQALPALEE-------LEEEELEELLAALGLPPDLSPE 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1283 QIEDVnnkgiikdktVSDVQDKFTEIIAKIRADAERQVQIIEERNKDLIIKYN-ETREQLYRLET---EKVERESTLRQL 1358
Cdd:COG4717 338 ELLEL----------LDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGvEDEEELRAALEqaeEYQELKEELEEL 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1359 QQELADALKKL--SMSEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERlHHQLKNLLEDKEREVMAVS 1436
Cdd:COG4717 408 EEQLEELLGELeeLLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEE-DGELAELLQELEELKAELR 486
|
490 500
....*....|....*....|....
gi 1774923325 1437 QKVQEYSSAAAGD---ENAIKELE 1457
Cdd:COG4717 487 ELAEEWAALKLALellEEAREEYR 510
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
139-220 |
2.58e-05 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 49.13 E-value: 2.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 139 HLAALIPSVSiAKQLLEHGANINAFNKEGCTPLILAVTENNEEMVEFLLKEGADINACDRGGRTSLMISSNNGQNNLVRI 218
Cdd:PTZ00322 88 QLAASGDAVG-ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQL 166
|
..
gi 1774923325 219 LL 220
Cdd:PTZ00322 167 LS 168
|
|
| PHA02946 |
PHA02946 |
ankyin-like protein; Provisional |
120-219 |
3.80e-05 |
|
ankyin-like protein; Provisional
Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 48.51 E-value: 3.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 120 LLEHNADPNLVDINGNAALHLAALIPSVSIAKQLLEHGANINAFNKEGCTPLILAVTENNE--EMVEFLLKEGADI-NAC 196
Cdd:PHA02946 58 LLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLYYLSGTDDEviERINLLVQYGAKInNSV 137
|
90 100
....*....|....*....|...
gi 1774923325 197 DRGGRTSLMISSNNGQNNLVRIL 219
Cdd:PHA02946 138 DEEGCGPLLACTDPSERVFKKIM 160
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
67-96 |
4.60e-05 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 41.80 E-value: 4.60e-05
10 20 30
....*....|....*....|....*....|
gi 1774923325 67 ENRTPLHIACANGQLDTVKVLLEHKSKLNL 96
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
1083-1488 |
4.81e-05 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 48.58 E-value: 4.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1083 LKEKIADLRRDLKMNEetltqtvIQYNSQLHALKTENTMLCSKLEHEKQGKDRLETELESIRSRL----TSTLQEVERNQ 1158
Cdd:pfam05557 7 SKARLSQLQNEKKQME-------LEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREaeaeEALREQAELNR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1159 ALKIEVERTLQRERDEWLRSQDkLNHELSTIRENNNNLSQQLIRAETKSNSLENEL----------RQTNTSLQDKVILS 1228
Cdd:pfam05557 80 LKKKYLEALNKKLNEKESQLAD-AREVISCLKNELSELRRQIQRAELELQSTNSELeelqerldllKAKASEAEQLRQNL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1229 ESTQRELTHTCGRIKELEHTLQL-EKDKICKSTVKQE-----SLQEKLAQIQSENMLLRQQIEdvnNKGIIKD-----KT 1297
Cdd:pfam05557 159 EKQQSSLAEAEQRIKELEFEIQSqEQDSEIVKNSKSElaripELEKELERLREHNKHLNENIE---NKLLLKEevedlKR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1298 VSDVQDKFTEIIAKIRADAERQVQIIEERNKdliikynetREQLYRLETEKVEREST-LRQLQQELADALKKLSMSEASL 1376
Cdd:pfam05557 236 KLEREEKYREEAATLELEKEKLEQELQSWVK---------LAQDTGLNLRSPEDLSRrIEQLQQREIVLKEENSSLTSSA 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1377 EVITRYRNDIEGEKQILQKEVEKFRIKvqdLEEQCNQAERLhhQLKNLLEDKEREVMavSQKVQEYSSAAAGDENA---- 1452
Cdd:pfam05557 307 RQLEKARRELEQELAQYLKKIEDLNKK---LKRHKALVRRL--QRRVLLLTKERDGY--RAILESYDKELTMSNYSpqll 379
|
410 420 430
....*....|....*....|....*....|....*...
gi 1774923325 1453 --IKELEGHVQKLEIENAKFEAtakqqagQIDILQKEL 1488
Cdd:pfam05557 380 erIEEAEDMTQKMQAHNEEMEA-------QLSVAEEEL 410
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1129-1567 |
5.49e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 48.50 E-value: 5.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1129 EKQGKDrLETELESIRSRLTSTLQEVERNQALKIEVERTLQrERDEWLRSQDKLNHELSTIRENNNNLSQQLIRAETKSN 1208
Cdd:PRK02224 198 EKEEKD-LHERLNGLESELAELDEEIERYEEQREQARETRD-EADEVLEEHEERREELETLEAEIEDLRETIAETERERE 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1209 SLENELRqtntslqdkvilsesTQRELTHTCG-RIKELEHTLQLEKDKICKSTVKQESLQEKLAQIQSENMLLRQQIEDV 1287
Cdd:PRK02224 276 ELAEEVR---------------DLRERLEELEeERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAH 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1288 NNKgiikdktvsdvqdkfteiIAKIRADAERqvqiIEERNKDLIIKYNETREQLYRLETEKVERESTLRQLQQELADALK 1367
Cdd:PRK02224 341 NEE------------------AESLREDADD----LEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRE 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1368 KLSMSEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLhhqlknLLEDKEREvmaVSQKVQE--YSSA 1445
Cdd:PRK02224 399 RFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAL------LEAGKCPE---CGQPVEGspHVET 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1446 AAGDENAIKELEGHVQKLEIENAKFEA------TAKQQAGQIDILqKELRETlsirhkLEELIASLQSSKMGLEEKLNHQ 1519
Cdd:PRK02224 470 IEEDRERVEELEAELEDLEEEVEEVEErleraeDLVEAEDRIERL-EERRED------LEELIAERRETIEEKRERAEEL 542
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 1774923325 1520 VHKQTALSQSAQDSHNLWEEELKSRSRLGIRLAELEHEKAEFADQVES 1567
Cdd:PRK02224 543 RERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIES 590
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
879-1599 |
5.80e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.60 E-value: 5.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 879 ASKVKKMENEKKDLQQIAEKNRELKSMLDHQKVESESDLNSLRFTLKQEEEKRKNAEMlyGKSQEqlRRKEDQCCQEMEA 958
Cdd:PTZ00121 1226 AEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADEL--KKAEE--KKKADEAKKAEEK 1301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 959 KQLLELtiRNLELEMRSMQNTVRQVEEERNEVQRLLSHEHNARIAQEDILNNIRRKSEEIENEKMWTKNAEVHGQLSKID 1038
Cdd:PTZ00121 1302 KKADEA--KKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKK 1379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1039 EREKDLILQNSNLQEEMNVlKLELDHVRSQNQQEESKYMDENENLKEKIADLRR--DLKMNEETLTQTVIQYNSQLHALK 1116
Cdd:PTZ00121 1380 ADAAKKKAEEKKKADEAKK-KAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKadEAKKKAEEAKKADEAKKKAEEAKK 1458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1117 TENtmLCSKLEHEKQGKDRLETELESIRSRLTSTLQEVERNQALKIEVERTLQRERDEWLRSQDKLNHELSTIRENNNNl 1196
Cdd:PTZ00121 1459 AEE--AKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKK- 1535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1197 SQQLIRAETKSNSLE----NELRQTntslqDKVILSESTQRELTHTCGRIKELEHTLQLEKDKICKSTVKQESLQEKLAQ 1272
Cdd:PTZ00121 1536 ADEAKKAEEKKKADElkkaEELKKA-----EEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAE 1610
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1273 IQSENMLLRQQIEDVNNKGIIKdktvsdvqdKFTEIIAKIRADAERQVQIIEERNKDLIIKynetREQLYRLETEKVERE 1352
Cdd:PTZ00121 1611 EAKKAEEAKIKAEELKKAEEEK---------KKVEQLKKKEAEEKKKAEELKKAEEENKIK----AAEEAKKAEEDKKKA 1677
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1353 STLRQLQQE---LADALKKLSMSEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKnlLEDKE 1429
Cdd:PTZ00121 1678 EEAKKAEEDekkAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAK--KDEEE 1755
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1430 REVMAVSQKVQEYSSAAAGDENAIKELEGHVQKLEIENAKFEATAKQQAGQIDILQKELRETLSIRHKLEELIAS----- 1504
Cdd:PTZ00121 1756 KKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSaikev 1835
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1505 LQSSKMGLEEKLNHQVHKQTALSQSAQDSHNL--WEEELKSRSRLGIRLAELEHEKAEFADQVESEKKKVKKLIEHKRSM 1582
Cdd:PTZ00121 1836 ADSKNMQLEEADAFEKHKFNKNNENGEDGNKEadFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDII 1915
|
730
....*....|....*....
gi 1774923325 1583 EARFDQE--IKRNAELQRD 1599
Cdd:PTZ00121 1916 DDKLDKDeyIKRDAEETRE 1934
|
|
| PHA02798 |
PHA02798 |
ankyrin-like protein; Provisional |
60-228 |
6.04e-05 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 47.91 E-value: 6.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 60 DINQLDKENRTPLHIACANGQLDTVKVLL---EHKSKLNLCDNDNRSPL---LKAIQCQQESCATVLLEHNADPNLVDiN 133
Cdd:PHA02798 101 DINKKNSDGETPLYCLLSNGYINNLEILLfmiENGADTTLLDKDGFTMLqvyLQSNHHIDIEIIKLLLEKGVDINTHN-N 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 134 GNAALHLAALIP------SVSIAKQLLEHGANINAFNKE---------------------------------------GC 168
Cdd:PHA02798 180 KEKYDTLHCYFKynidriDADILKLFVDNGFIINKENKShkkkfmeylnsllydnkrfkknildfifsyidinqvdelGF 259
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 169 TPLILAVTENNEEMVEFLLKEGADINACDRGGRTSLMISSNNGQNNLVRILLQNEADINI 228
Cdd:PHA02798 260 NPLYYSVSHNNRKIFEYLLQLGGDINIITELGNTCLFTAFENESKFIFNSILNKKPNKNT 319
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1138-1597 |
6.56e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.84 E-value: 6.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1138 TELESIRSRLTSTLQ----EVERNQALKIEVERTLQRERDEWLRSQDKLNHELSTIRENNNNLSQQLIRAETKSNSLENE 1213
Cdd:COG4717 38 TLLAFIRAMLLERLEkeadELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREE 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1214 LRQTNTSLQ--DKVILSESTQRELTHTCGRIKELEHTLQlekdkickstvKQESLQEKLAQIQSENMLLRQQIED-VNNK 1290
Cdd:COG4717 118 LEKLEKLLQllPLYQELEALEAELAELPERLEELEERLE-----------ELRELEEELEELEAELAELQEELEElLEQL 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1291 GIIKDKTVSDVQDKFTEIIAKIRAdAERQVQIIEERNKDLiikynetREQLYRLETEKvERESTLRQLQQE--------- 1361
Cdd:COG4717 187 SLATEEELQDLAEELEELQQRLAE-LEEELEEAQEELEEL-------EEELEQLENEL-EAAALEERLKEArlllliaaa 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1362 ------LADALKKLSMSEA-----SLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKER 1430
Cdd:COG4717 258 llallgLGGSLLSLILTIAgvlflVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPE 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1431 EVMAVSQKVQEYSSAAAGDENAIKELEGHVQKLEIEN--AKFEATAKQQAGQIDILQKELREtlsIRHKLEELIASLQSS 1508
Cdd:COG4717 338 ELLELLDRIEELQELLREAEELEEELQLEELEQEIAAllAEAGVEDEEELRAALEQAEEYQE---LKEELEELEEQLEEL 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1509 KMGLEEKLnhQVHKQTALSQSAQDSHNLWEEELKSRSRLGIRLAELEHEKAEFADQVESEkkkvkKLIEHKRSMEARFDQ 1588
Cdd:COG4717 415 LGELEELL--EALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELA-----ELLQELEELKAELRE 487
|
....*....
gi 1774923325 1589 EIKRNAELQ 1597
Cdd:COG4717 488 LAEEWAALK 496
|
|
| PHA02859 |
PHA02859 |
ankyrin repeat protein; Provisional |
47-211 |
8.43e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165195 [Multi-domain] Cd Length: 209 Bit Score: 45.97 E-value: 8.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 47 GDVGKIKQLIKKqdINQLDKENRTPLHiAC---ANGQLDTVKVLLEHKSKLN-LCDNDNRSPL---LKAIQCQQESCATV 119
Cdd:PHA02859 32 DDIEGVKKWIKF--VNDCNDLYETPIF-SClekDKVNVEILKFLIENGADVNfKTRDNNLSALhhyLSFNKNVEPEILKI 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 120 LLEHNADPNLVDINGNAALH--LAALIPSVSIAKQLLEHGANInaFNKEGCTPLIL---AVTENNEEMVEFLLKEGADIN 194
Cdd:PHA02859 109 LIDSGSSITEEDEDGKNLLHmyMCNFNVRINVIKLLIDSGVSF--LNKDFDNNNILysyILFHSDKKIFDFLTSLGIDIN 186
|
170
....*....|....*..
gi 1774923325 195 ACDRGGRTSLMISSNNG 211
Cdd:PHA02859 187 ETNKSGYNCYDLIKFRN 203
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
149-230 |
8.74e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 47.75 E-value: 8.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 149 IAKQLLEHGANINAFNKEGCTPLILAVTENNEEMVEFLLKEGADINACDRGGRTSLMISSNNGQNNLVRILLQNEADINI 228
Cdd:PHA02876 160 IAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIIDNRSNINK 239
|
..
gi 1774923325 229 KD 230
Cdd:PHA02876 240 ND 241
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
869-1442 |
1.04e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.83 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 869 QRENGRYKLLASKVKKMENEKKDlQQIAEKNRELKSMLDHQKVESESDLNSLRFTLKQEEEKRKNAEMlygKSQEQLRRK 948
Cdd:PTZ00121 1351 EAEAAADEAEAAEEKAEAAEKKK-EEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK---KKADEAKKK 1426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 949 EDQCCQEMEAKQLLELTIRNLEL-----EMRSMQNTVRQVEEERnEVQRLLSHEHNARIAQE--DILNNIRRKSEEIENE 1021
Cdd:PTZ00121 1427 AEEKKKADEAKKKAEEAKKADEAkkkaeEAKKAEEAKKKAEEAK-KADEAKKKAEEAKKADEakKKAEEAKKKADEAKKA 1505
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1022 KMWTKNAEvhgQLSKIDEREKDLILQNSNLQEEMNVLKL--------ELDHVRSQNQQEESKYMDENENLKE-KIADLRR 1092
Cdd:PTZ00121 1506 AEAKKKAD---EAKKAEEAKKADEAKKAEEAKKADEAKKaeekkkadELKKAEELKKAEEKKKAEEAKKAEEdKNMALRK 1582
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1093 --DLKMNEETLTQTVIQYNSQLHALKTENTmlcSKLEHEKQGKDRL---ETELESIRSRLTSTLQEVERNQALKIEVERT 1167
Cdd:PTZ00121 1583 aeEAKKAEEARIEEVMKLYEEEKKMKAEEA---KKAEEAKIKAEELkkaEEEKKKVEQLKKKEAEEKKKAEELKKAEEEN 1659
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1168 LQRERDEWLRSQD--KLNHELSTIRENNNNLSQQLIRAETKSNSLEnelrQTNTSLQDKVILSESTQRELTHTCGRIKEL 1245
Cdd:PTZ00121 1660 KIKAAEEAKKAEEdkKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE----ELKKKEAEEKKKAEELKKAEEENKIKAEEA 1735
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1246 EHTLQLEKDKiCKSTVKQESLQEKLAQIQSENMLLRQQIEDvNNKGIIKDKTVSDVQDKFTEIIAKIRaDAERQVQIIEE 1325
Cdd:PTZ00121 1736 KKEAEEDKKK-AEEAKKDEEEKKKIAHLKKEEEKKAEEIRK-EKEAVIEEELDEEDEKRRMEVDKKIK-DIFDNFANIIE 1812
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1326 RNKDLIIKYNETREqlyrLETEKVERESTLRQLQQELADALKKLSMSEASLEVITRYRN-DIEGEKQILQKEVEKfrIKV 1404
Cdd:PTZ00121 1813 GGKEGNLVINDSKE----MEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEaDFNKEKDLKEDDEEE--IEE 1886
|
570 580 590
....*....|....*....|....*....|....*...
gi 1774923325 1405 QDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEY 1442
Cdd:PTZ00121 1887 ADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEY 1924
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
133-165 |
1.04e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 41.12 E-value: 1.04e-04
10 20 30
....*....|....*....|....*....|....
gi 1774923325 133 NGNAALHLAALIP-SVSIAKQLLEHGANINAFNK 165
Cdd:pfam00023 1 DGNTPLHLAAGRRgNLEIVKLLLSKGADVNARDK 34
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1345-1516 |
1.11e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 46.75 E-value: 1.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1345 ETEKVERESTLRQLQQELADALKKLSMSEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQ-----AERLHH 1419
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEErreelGERARA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1420 QLKNLLEDKEREVMAVSQKVQEY-------SSAAAGDENAIKELEGHVQKLEIENAKFEATAKQQAGQIDILQKELRETL 1492
Cdd:COG3883 95 LYRSGGSVSYLDVLLGSESFSDFldrlsalSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE 174
|
170 180
....*....|....*....|....
gi 1774923325 1493 SIRHKLEELIASLQSSKMGLEEKL 1516
Cdd:COG3883 175 AQQAEQEALLAQLSAEEAAAEAQL 198
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1390-1841 |
1.20e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 47.42 E-value: 1.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1390 KQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEYSSAAA--------GDENAIKELEGHVQ 1461
Cdd:pfam15921 73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMAdirrresqSQEDLRNQLQNTVH 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1462 KLEIENAKFEATAKQQAGQIDILQKelretLSIRHklEELIASLQSSKMGLEEKLNHQVHKQTALsqSAQDSHNLWEEEL 1541
Cdd:pfam15921 153 ELEAAKCLKEDMLEDSNTQIEQLRK-----MMLSH--EGVLQEIRSILVDFEEASGKKIYEHDSM--STMHFRSLGSAIS 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1542 KSRSRLGIRLAELEHEKAEFADQVESEKKKVKKLIE-HKRSMEARFDQEIkrnAELQRDISGLKKLLKTAKKK----IKE 1616
Cdd:pfam15921 224 KILRELDTEISYLKGRIFPVEDQLEALKSESQNKIElLLQQHQDRIEQLI---SEHEVEITGLTEKASSARSQansiQSQ 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1617 LESVGTQQSTQDGFKSTHF-EKEIDIMKLKEKINELSFRLENESSNY-KQLEAANRDLQQQLSSMKMFHKSQEHLEKgkr 1694
Cdd:pfam15921 301 LEIIQEQARNQNSMYMRQLsDLESTVSQLRSELREAKRMYEDKIEELeKQLVLANSELTEARTERDQFSQESGNLDD--- 377
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1695 QLEDEVANL-KRQIEInkvdqSLIEKHKREIEERGR------LELKQKLEEVNLFLQSqaasqetLEQIRAANDASVRNQ 1767
Cdd:pfam15921 378 QLQKLLADLhKREKEL-----SLEKEQNKRLWDRDTgnsitiDHLRRELDDRNMEVQR-------LEALLKAMKSECQGQ 445
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1774923325 1768 MEHRIQELEsdlgkiknAQQENMLQRESTQTELERFKELYNEELKNRNSLALKLERSNERLADANAKlLNERQR 1841
Cdd:pfam15921 446 MERQMAAIQ--------GKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTAS-LQEKER 510
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
1005-1555 |
1.24e-04 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 47.20 E-value: 1.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1005 EDILNNIRRKSEEIENEKMwtknaevhgQLSKIDEREKDLILQNSNLQEEMNVLKLELDHVRSQnQQEESKYMDENENLK 1084
Cdd:PRK01156 186 DYLEEKLKSSNLELENIKK---------QIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSA-LNELSSLEDMKNRYE 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1085 EKIADLRRDLKMNEETltqtVIQYNSQLHALKTENTMLCSKLEHEKQGKDRLETELESIRSRLTSTLQEVERNQALKIEV 1164
Cdd:PRK01156 256 SEIKTAESDLSMELEK----NNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAIIKKL 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1165 ErTLQRERDEWLRSQ---DKLNHELSTIRENNNNLSQQLIRAETKSNSLENELRQTNTSLQDKVILSESTQRELTHTCGR 1241
Cdd:PRK01156 332 S-VLQKDYNDYIKKKsryDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKE 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1242 IKELEHTLQLEKDKICKSTVKQESLQEKLAQI-QSENMLLRQQIEDVNNKGIIKDKT---VSDVQDKFTEIIAKIRaDAE 1317
Cdd:PRK01156 411 LNEINVKLQDISSKVSSLNQRIRALRENLDELsRNMEMLNGQSVCPVCGTTLGEEKSnhiINHYNEKKSRLEEKIR-EIE 489
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1318 RQVQIIEERNKDLIikynetrEQLYRLETEKVERESTLRQLQQELADALKKLSMSEASL-EVITRYRNDIEGEKQILQKE 1396
Cdd:PRK01156 490 IEVKDIDEKIVDLK-------KRKEYLESEEINKSINEYNKIESARADLEDIKIKINELkDKHDKYEEIKNRYKSLKLED 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1397 VEKFR---------IKVQDLEEQCNQAERLHHQLKNlLEDKEREVMAVSQKVQEYSsaaagdENAIKELEGHVQKLeiEN 1467
Cdd:PRK01156 563 LDSKRtswlnalavISLIDIETNRSRSNEIKKQLND-LESRLQEIEIGFPDDKSYI------DKSIREIENEANNL--NN 633
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1468 AKFEATAKQQA-----GQIDILQKELRETLSIRHKLEELIASLQSSkmglEEKLNhQVHKQTALSQSAQDSHNLWEEELK 1542
Cdd:PRK01156 634 KYNEIQENKILieklrGKIDNYKKQIAEIDSIIPDLKEITSRINDI----EDNLK-KSRKALDDAKANRARLESTIEILR 708
|
570
....*....|....
gi 1774923325 1543 SR-SRLGIRLAELE 1555
Cdd:PRK01156 709 TRiNELSDRINDIN 722
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1194-1415 |
1.30e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 46.36 E-value: 1.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1194 NNLSQQLIRAETKSNSLENELRQTNTSLQDKVILSESTQRELTHTCGRIKELehtlqlekdkickstvkQESLQEKLAQI 1273
Cdd:COG3883 19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKL-----------------QAEIAEAEAEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1274 QSENMLLRQQIEDVNNKGiikdKTVSDVQ-----DKFTEIIAKIRAdaerqVQIIEERNKDLIIKYNETREQLYRLETEK 1348
Cdd:COG3883 82 EERREELGERARALYRSG----GSVSYLDvllgsESFSDFLDRLSA-----LSKIADADADLLEELKADKAELEAKKAEL 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1774923325 1349 VERESTLRQLQQELADALKKLsmsEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAE 1415
Cdd:COG3883 153 EAKLAELEALKAELEAAKAEL---EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAA 216
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
1323-1534 |
1.35e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 46.84 E-value: 1.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1323 IEERNKDLII----KYNETREQLYRL---------ETEKVERESTLRQLQQELADALKKLS---------------MSEA 1374
Cdd:PRK05771 3 PVRMKKVLIVtlksYKDEVLEALHELgvvhiedlkEELSNERLRKLRSLLTKLSEALDKLRsylpklnplreekkkVSVK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1375 SLEVITRYR----NDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHH---QLKNLL-------------EDKEREVMA 1434
Cdd:PRK05771 83 SLEELIKDVeeelEKIEKEIKELEEEISELENEIKELEQEIERLEPWGNfdlDLSLLLgfkyvsvfvgtvpEDKLEELKL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1435 VSQKVQEYSSAAAGDENAI-------------KELEGH-VQKLEI-ENAKFEATAKQQAGQIDILQKELREtlsIRHKLE 1499
Cdd:PRK05771 163 ESDVENVEYISTDKGYVYVvvvvlkelsdeveEELKKLgFERLELeEEGTPSELIREIKEELEEIEKERES---LLEELK 239
|
250 260 270
....*....|....*....|....*....|....*
gi 1774923325 1500 ELIASLQSSKMGLEEKLNHQVHKQTALSQSAQDSH 1534
Cdd:PRK05771 240 ELAKKYLEELLALYEYLEIELERAEALSKFLKTDK 274
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
1318-1751 |
1.39e-04 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 47.04 E-value: 1.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1318 RQVQIIEERNKDLIIKYNETREQLYRLETEKVERESTLRQLQQELADALKKLSMSEASL----EVITRYRNDIEGEKQIL 1393
Cdd:pfam05557 41 RQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQLadarEVISCLKNELSELRRQI 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1394 QK----------EVEKFRIKVQDLEEQCNQAERLHHQLK---NLLEDKEREVMAVSQKVQEYSSAAAGDENA------IK 1454
Cdd:pfam05557 121 QRaelelqstnsELEELQERLDLLKAKASEAEQLRQNLEkqqSSLAEAEQRIKELEFEIQSQEQDSEIVKNSkselarIP 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1455 ELEGHVQKLEIENAKFEATakqqAGQIDILQKE---LRETLSIRHKLEELIASLQSSKMGLEEKLNH-----QVHKQT-- 1524
Cdd:pfam05557 201 ELEKELERLREHNKHLNEN----IENKLLLKEEvedLKRKLEREEKYREEAATLELEKEKLEQELQSwvklaQDTGLNlr 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1525 ---ALS----QSAQDSHNLWEE--ELKSRSR-LGIRLAELEHEKAEFADQVESEKKKVKKLIEHKRSMEAR--------- 1585
Cdd:pfam05557 277 speDLSrrieQLQQREIVLKEEnsSLTSSARqLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRvllltkerd 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1586 --------FDQEI---KRNAELQRDISGLKKLLKTAKKKIKELE-SVGTQQSTQDGFK--STHFEKEIDIMKLKEKINEL 1651
Cdd:pfam05557 357 gyrailesYDKELtmsNYSPQLLERIEEAEDMTQKMQAHNEEMEaQLSVAEEELGGYKqqAQTLERELQALRQQESLADP 436
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1652 SFRLENESSNYKQ---LEAANRDLQQQ------------------LSSMKMFHKSQEHLEKGKRQLEDEVANLKRQIE-- 1708
Cdd:pfam05557 437 SYSKEEVDSLRRKletLELERQRLREQknelemelerrclqgdydPKKTKVLHLSMNPAAEAYQQRKNQLEKLQAEIErl 516
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 1774923325 1709 --INKVDQSLIEKHKR------EIEERGRLELKQKLEEVNLFLQS-----QAASQE 1751
Cdd:pfam05557 517 krLLKKLEDDLEQVLRlpettsTMNFKEVLDLRKELESAELKNQRlkevfQAKIQE 572
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1328-1835 |
1.39e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.22 E-value: 1.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1328 KDLIIKYNETREQLYRLEtEKVERESTLRQLQQELADALKKLSMSEASLEVITRYRNdiEGEKQILQKEVEKFRIKVQDL 1407
Cdd:COG4913 231 VEHFDDLERAHEALEDAR-EQIELLEPIRELAERYAAARERLAELEYLRAALRLWFA--QRRLELLEAELEELRAELARL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1408 EEQCNQAERLHHQLKNLLEDKEREVmavsqkvqeysSAAAGDEnaIKELEGhvqkleienakfeatakqqagQIDILQKE 1487
Cdd:COG4913 308 EAELERLEARLDALREELDELEAQI-----------RGNGGDR--LEQLER---------------------EIERLERE 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1488 LRETLSIRHKLEELIASLQSSKMGLEEKLNHQvhkQTALSQSAQDSHNLWEEELKSRSRLGIRLAELEHEKAEFADQVES 1567
Cdd:COG4913 354 LEERERRRARLEALLAALGLPLPASAEEFAAL---RAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIAS 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1568 ekkkvkklIEHKRS------MEARfdQEIKRNAELQRD---ISGlkkllktakkkikELESVGTQQST-QD-------GF 1630
Cdd:COG4913 431 --------LERRKSniparlLALR--DALAEALGLDEAelpFVG-------------ELIEVRPEEERwRGaiervlgGF 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1631 K------------------STHFEKEIDIMKLKEK--------------INELSFRlENESSNYKQLEAANR------DL 1672
Cdd:COG4913 488 AltllvppehyaaalrwvnRLHLRGRLVYERVRTGlpdperprldpdslAGKLDFK-PHPFRAWLEAELGRRfdyvcvDS 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1673 QQQLSSMK-------MFHKSQEHLEKGKRQ------------------LEDEVANLKRqiEINKVDQSlIEKHKREIEE- 1726
Cdd:COG4913 567 PEELRRHPraitragQVKGNGTRHEKDDRRrirsryvlgfdnraklaaLEAELAELEE--ELAEAEER-LEALEAELDAl 643
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1727 RGRLELKQKLEEVNLFLQSQAASQETLEQIRAandasvrnqmehRIQELESDLGKIKNAQQenmlQRESTQTELERFKEL 1806
Cdd:COG4913 644 QERREALQRLAEYSWDEIDVASAEREIAELEA------------ELERLDASSDDLAALEE----QLEELEAELEELEEE 707
|
570 580
....*....|....*....|....*....
gi 1774923325 1807 YNEELKNRNSLALKLERSNERLADANAKL 1835
Cdd:COG4913 708 LDELKGEIGRLEKELEQAEEELDELQDRL 736
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
69-99 |
1.40e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 40.74 E-value: 1.40e-04
10 20 30
....*....|....*....|....*....|..
gi 1774923325 69 RTPLHIACA-NGQLDTVKVLLEHKSKLNLCDN 99
Cdd:pfam00023 3 NTPLHLAAGrRGNLEIVKLLLSKGADVNARDK 34
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
860-1921 |
1.73e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 46.97 E-value: 1.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 860 IIHEYERTIQRENGRYKLLASKVKKMENEKKDLQQIAEKNRELKSMLDHQkveseSDLNSLRftlkqEEEKRKNaemlYG 939
Cdd:TIGR01612 749 INKDLNKILEDFKNKEKELSNKINDYAKEKDELNKYKSKISEIKNHYNDQ-----INIDNIK-----DEDAKQN----YD 814
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 940 KSQEQLRrkedqccqemeakqllelTIRNLELEMRSMQNTVRQVEEE-RNEVQRLLSHEHNAR----IAQEDILNNIRRK 1014
Cdd:TIGR01612 815 KSKEYIK------------------TISIKEDEIFKIINEMKFMKDDfLNKVDKFINFENNCKekidSEHEQFAELTNKI 876
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1015 SEEIENEKMWTKNAEVHGQLSKIDEREKDLILQNSNLqeemNVLKleldhvrsqnqqEESKYMDENENLKEKIADLRrdl 1094
Cdd:TIGR01612 877 KAEISDDKLNDYEKKFNDSKSLINEINKSIEEEYQNI----NTLK------------KVDEYIKICENTKESIEKFH--- 937
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1095 kmNEETLTQTVIqyNSQLHALKTENTMlcsklehEKQGKDRLETELESIRSRLTSTLQEVERNqalkieverTLQRERDE 1174
Cdd:TIGR01612 938 --NKQNILKEIL--NKNIDTIKESNLI-------EKSYKDKFDNTLIDKINELDKAFKDASLN---------DYEAKNNE 997
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1175 WLRSQDKLNHELSTIREnnNNLSQQLIRAETKSNSLENELRQTNTSLQDKVILSEST----QRELTHTCGRIKELEHTLQ 1250
Cdd:TIGR01612 998 LIKYFNDLKANLGKNKE--NMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSiyniIDEIEKEIGKNIELLNKEI 1075
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1251 LEKDKIckSTVKQESLQEKLAQIQSENMLLRQQIEDVNNKGIIKD--KTVSDVQDKFTEIIAKIRADAERQVQIIEERNK 1328
Cdd:TIGR01612 1076 LEEAEI--NITNFNEIKEKLKHYNFDDFGKEENIKYADEINKIKDdiKNLDQKIDHHIKALEEIKKKSENYIDEIKAQIN 1153
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1329 DL-----IIKYNETREQLYRleteKVERESTLRQLQQELADALKKLSMSEASLEVITRYRNDIEGEKQILQKEVEKfrIK 1403
Cdd:TIGR01612 1154 DLedvadKAISNDDPEEIEK----KIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTSLEEVKGINLSYGKNLGK--LF 1227
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1404 VQDLEEQCNQAERLHHQLKNLLEDKERevmaVSQKVQEYSSAAAGDENAIKELEghvqKLEIENAKFE---ATAKQQAGQ 1480
Cdd:TIGR01612 1228 LEKIDEEKKKSEHMIKAMEAYIEDLDE----IKEKSPEIENEMGIEMDIKAEME----TFNISHDDDKdhhIISKKHDEN 1299
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1481 I-DILQKELRETLSIRHKleeliASLQSSKMGLEEKLNHQVHKQTALSQSAQDSHNLWE-EELKSRSRLGIRLAELEHEK 1558
Cdd:TIGR01612 1300 IsDIREKSLKIIEDFSEE-----SDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNiLKLNKIKKIIDEVKEYTKEI 1374
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1559 AEFADQVESEKKKVKKLIehkrsmearfdQEIKRNAELQrdisglkkllktakkkikelESVGTQQSTQDGfksthfeKE 1638
Cdd:TIGR01612 1375 EENNKNIKDELDKSEKLI-----------KKIKDDINLE--------------------ECKSKIESTLDD-------KD 1416
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1639 ID--IMKLKEKINELSFRLENESSNYKQLEAANRDLQQQLSSMKMFHKSQEHLEKGKRQ-----LEDEVANLKRQIEINK 1711
Cdd:TIGR01612 1417 IDecIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILKIKKDnatndHDFNINELKEHIDKSK 1496
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1712 VDQSLIEKHKREIEERGRLeLKQKLEEVNLFLQSQAAsqetleqiraandASVRNQMEHRIQELESDLGKIKNAQQENML 1791
Cdd:TIGR01612 1497 GCKDEADKNAKAIEKNKEL-FEQYKKDVTELLNKYSA-------------LAIKNKFAKTKKDSEIIIKEIKDAHKKFIL 1562
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1792 QRESTQtelERFKELYNEELKNRNSLAlKLERSNERLADANAKLlnERQRTKSLIASSI---MNGSLATSPVVDASSfgn 1868
Cdd:TIGR01612 1563 EAEKSE---QKIKEIKKEKFRIEDDAA-KNDKSNKAAIDIQLSL--ENFENKFLKISDIkkkINDCLKETESIEKKI--- 1633
|
1050 1060 1070 1080 1090
....*....|....*....|....*....|....*....|....*....|....*.
gi 1774923325 1869 fsnSGFRLGGSFLSSTANGMNTNRVENYLTKMQQElEKNI---TKELDQANAELES 1921
Cdd:TIGR01612 1634 ---SSFSIDSQDTELKENGDNLNSLQEFLESLKDQ-KKNIedkKKELDELDSEIEK 1685
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
956-1469 |
2.00e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.45 E-value: 2.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 956 MEAKQLLELTIRNLEL--EMRSMQNTVRQVEEERNEVQRLLSHEHNARIAQEDILNNIRRKSEEIENEKMWTKNAEVHGQ 1033
Cdd:COG4913 238 ERAHEALEDAREQIELlePIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEAR 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1034 LSKIDEREKDL---ILQNS-----NLQEEMNVLKLELDHVrsqnQQEESKYMDENENLKEKIADLRRDLKMNEETLTQTV 1105
Cdd:COG4913 318 LDALREELDELeaqIRGNGgdrleQLEREIERLERELEER----ERRRARLEALLAALGLPLPASAEEFAALRAEAAALL 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1106 IQYNSQLHALKTENTMLCSKLEHEKQGKDRLETELESIRSR---LTSTLQEVER--NQALKIEVERT------LQ-RERD 1173
Cdd:COG4913 394 EALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRksnIPARLLALRDalAEALGLDEAELpfvgelIEvRPEE 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1174 E-W-------LRSQdKLN------HELSTIRE-NNNNLSQQLI--RAETKSNSLENELRQTNtSLQDKVILSESTQRElt 1236
Cdd:COG4913 474 ErWrgaiervLGGF-ALTllvppeHYAAALRWvNRLHLRGRLVyeRVRTGLPDPERPRLDPD-SLAGKLDFKPHPFRA-- 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1237 htcgrikELEHTLQLEKDKICKSTVKQeslqeklaqiqsenmlLRQ---------QIEDVNNKGIIKDKTV--------S 1299
Cdd:COG4913 550 -------WLEAELGRRFDYVCVDSPEE----------------LRRhpraitragQVKGNGTRHEKDDRRRirsryvlgF 606
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1300 DVQDKFTEIIAKIRAdAERQVQIIEERNKDL--IIKYNETREQLYRLETEKVERESTLRQLQQELA---DALKKLSMSEA 1374
Cdd:COG4913 607 DNRAKLAALEAELAE-LEEELAEAEERLEALeaELDALQERREALQRLAEYSWDEIDVASAEREIAeleAELERLDASSD 685
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1375 SLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKE-REVMAVSQKVQEYSSAAAGDENA- 1452
Cdd:COG4913 686 DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEdLARLELRALLEERFAAALGDAVEr 765
|
570
....*....|....*....
gi 1774923325 1453 --IKELEGHVQKLEIENAK 1469
Cdd:COG4913 766 elRENLEERIDALRARLNR 784
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
879-1369 |
2.02e-04 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 46.44 E-value: 2.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 879 ASKVKKMENEKKDLQQIAEKNRELksmLDhQKVESESDLNSLRFTLKQEEEKRKNAemlygksQEQLRR-KEDQccQEME 957
Cdd:PRK11281 48 LNKQKLLEAEDKLVQQDLEQTLAL---LD-KIDRQKEETEQLKQQLAQAPAKLRQA-------QAELEAlKDDN--DEET 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 958 AKQLLELTIRNLELEMRSMQNTVRQVEEERNEVQRLLSHEHNARI-AQEDILNNIRRkSEEIENekmwtknaevhgQLSK 1036
Cdd:PRK11281 115 RETLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPErAQAALYANSQR-LQQIRN------------LLKG 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1037 IDEREKDLIlqnsnlQEEMNVLKLELDHVRSQNqqeeskymdenenlkekiaDLRRDLKMNEETLTQTviqYNSQlHALK 1116
Cdd:PRK11281 182 GKVGGKALR------PSQRVLLQAEQALLNAQN-------------------DLQRKSLEGNTQLQDL---LQKQ-RDYL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1117 TENTmlcsklehekqgkDRLETELEsirsrltsTLQEVeRNQALKIEVERTLQRerdewLRSQDKLNHE-----LSTIRE 1191
Cdd:PRK11281 233 TARI-------------QRLEHQLQ--------LLQEA-INSKRLTLSEKTVQE-----AQSQDEAARIqanplVAQELE 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1192 NNNNLSQQLIRAETKSNSLenelrqTNTSLQDKVILSESTQRELThtcgrIKElehtlQLekdkicksTVKQESLQekLA 1271
Cdd:PRK11281 286 INLQLSQRLLKATEKLNTL------TQQNLRVKNWLDRLTQSERN-----IKE-----QI--------SVLKGSLL--LS 339
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1272 QIqsenmLLRQQIEdvnnkgIIKDKTVSDVQDKfteiIAKIRadaerqVQIIEernkdliikYNETREQLYRLET--EKV 1349
Cdd:PRK11281 340 RI-----LYQQQQA------LPSADLIEGLADR----IADLR------LEQFE---------INQQRDALFQPDAyiDKL 389
|
490 500
....*....|....*....|
gi 1774923325 1350 ERESTlRQLQQELADALKKL 1369
Cdd:PRK11281 390 EAGHK-SEVTDEVRDALLQL 408
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
835-1095 |
2.09e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 46.59 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 835 RNAKMLIEQLGVDSQDSVNLLKFQNIIHEyeRTIQRENGRYKLLASKVKKMENEKKDLQQIAEKNRELKSMLDHQKVE-- 912
Cdd:TIGR02168 711 EEELEQLRKELEELSRQISALRKDLARLE--AEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEle 788
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 913 ------------SESDLNSLRFTLKQEEEKRKNAEMLYGKSQEQLRRKEDQCCQEMEAKQLLELTIRNLELEMRSMQNTV 980
Cdd:TIGR02168 789 aqieqlkeelkaLREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI 868
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 981 RQVEEERNEVQRLLSHEHNARIAQEDILNNIRRKSEEIENEKMWTKNA--EVHGQLSKIDEREKDLILQNSNLQEEMNVL 1058
Cdd:TIGR02168 869 EELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRREleELREKLAQLELRLEGLEVRIDNLQERLSEE 948
|
250 260 270
....*....|....*....|....*....|....*...
gi 1774923325 1059 -KLELDHVrsqnQQEESKYMDENENLKEKIADLRRDLK 1095
Cdd:TIGR02168 949 ySLTLEEA----EALENKIEDDEEEARRRLKRLENKIK 982
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
889-1753 |
2.21e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 46.58 E-value: 2.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 889 KKDLQQIAEKNRELKSMLDHQKVESESD--LNSL-RFTLKQEEEKRKNAEMLYGKSQEQLrrkedqccqemeaKQLLELT 965
Cdd:TIGR01612 606 KEKIKNISDKNEYIKKAIDLKKIIENNNayIDELaKISPYQVPEHLKNKDKIYSTIKSEL-------------SKIYEDD 672
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 966 IRNLELEMRSM--QNTVRQVEEE------RNEVQRLLSHEHNARIAQ-EDILNNIRRKSEEIENEKMWTKN---AEVHGQ 1033
Cdd:TIGR01612 673 IDALYNELSSIvkENAIDNTEDKaklddlKSKIDKEYDKIQNMETATvELHLSNIENKKNELLDIIVEIKKhihGEINKD 752
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1034 LSKIDE----REKDL---ILQNSNLQEEMNVLKLELDHVRSQNQQEESKYMDENENLK---EKIADLRRDLKMNEETLTQ 1103
Cdd:TIGR01612 753 LNKILEdfknKEKELsnkINDYAKEKDELNKYKSKISEIKNHYNDQINIDNIKDEDAKqnyDKSKEYIKTISIKEDEIFK 832
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1104 TViqynSQLHALKTENTMLCSK-LEHEKQGKDRLETELESIrsrltstlqeVERNQALKIEVertlqrerdewlrSQDKL 1182
Cdd:TIGR01612 833 II----NEMKFMKDDFLNKVDKfINFENNCKEKIDSEHEQF----------AELTNKIKAEI-------------SDDKL 885
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1183 NhelstIRENNNNLSQQLIRAETksNSLENELRQTNTslqdkvilsestqrelthtcgrIKELEHTLqlekdKICKSTvk 1262
Cdd:TIGR01612 886 N-----DYEKKFNDSKSLINEIN--KSIEEEYQNINT----------------------LKKVDEYI-----KICENT-- 929
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1263 QESLQEKLAQIQSENMLLRQQIEDVNNKGII----KDKTVSDVQDKFTEiIAKIRADAerQVQIIEERNKDLIIKYNETR 1338
Cdd:TIGR01612 930 KESIEKFHNKQNILKEILNKNIDTIKESNLIeksyKDKFDNTLIDKINE-LDKAFKDA--SLNDYEAKNNELIKYFNDLK 1006
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1339 EQLYR-----LETEKVERESTLRQLQQELADALKKLSMSEasLEVITRYRNDIEGEKQILQKEVEKFRIKVqdleeqcnq 1413
Cdd:TIGR01612 1007 ANLGKnkenmLYHQFDEKEKATNDIEQKIEDANKNIPNIE--IAIHTSIYNIIDEIEKEIGKNIELLNKEI--------- 1075
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1414 AERLHHQLKNLLEDKER-EVMAVSQKVQEYSSAAAGDENAIK--------ELEGHVQKLEIENAKFEATAKQQAGQIDIL 1484
Cdd:TIGR01612 1076 LEEAEINITNFNEIKEKlKHYNFDDFGKEENIKYADEINKIKddiknldqKIDHHIKALEEIKKKSENYIDEIKAQINDL 1155
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1485 QKELRETLS------IRHKLEELIASLQSSKmGLEEKLNHQVHKqtaLSQSAQDSHNLweEELKsrsrlGIRLAELEHEK 1558
Cdd:TIGR01612 1156 EDVADKAISnddpeeIEKKIENIVTKIDKKK-NIYDEIKKLLNE---IAEIEKDKTSL--EEVK-----GINLSYGKNLG 1224
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1559 AEFADQVESEKKKVKKLIehkRSMEARfdqeIKRNAELQRDISGLKKLLKTAKKKIKELESVGTQQSTQDGFKSTHFEKE 1638
Cdd:TIGR01612 1225 KLFLEKIDEEKKKSEHMI---KAMEAY----IEDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHD 1297
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1639 IDIMKLKEKinelSFRLENESSNYKQLEAANRDLQQQLSsmkmfhKSQEHLEKGKRQLeDEVANLKRQIEINKVdQSLIE 1718
Cdd:TIGR01612 1298 ENISDIREK----SLKIIEDFSEESDINDIKKELQKNLL------DAQKHNSDINLYL-NEIANIYNILKLNKI-KKIID 1365
|
890 900 910
....*....|....*....|....*....|....*
gi 1774923325 1719 KHKreieergrlELKQKLEEVNLFLQSQAASQETL 1753
Cdd:TIGR01612 1366 EVK---------EYTKEIEENNKNIKDELDKSEKL 1391
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
67-95 |
2.47e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 39.93 E-value: 2.47e-04
10 20
....*....|....*....|....*....
gi 1774923325 67 ENRTPLHIACANGQLDTVKVLLEHKSKLN 95
Cdd:pfam13606 1 DGNTPLHLAARNGRLEIVKLLLENGADIN 29
|
|
| DUF4686 |
pfam15742 |
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ... |
1159-1525 |
2.50e-04 |
|
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.
Pssm-ID: 464838 [Multi-domain] Cd Length: 384 Bit Score: 45.44 E-value: 2.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1159 ALKIEVERTLQRERDEWLRSQDKLNH---ELSTIRENNNNLSQQLIRAETKSNSLENELRQTNTSLQDKVILSESTQREL 1235
Cdd:pfam15742 6 KLKYQQQEEVQQLRQNLQRLQILCTSaekELRYERGKNLDLKQHNSLLQEENIKIKAELKQAQQKLLDSTKMCSSLTAEW 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1236 THTCGRIKELEhtlqLEKDKICKSTVKQESLQEKLAQIQS------ENMLLRQQIEDVNNKGIIKDKTVSDVQDKFTEII 1309
Cdd:pfam15742 86 KHCQQKIRELE----LEVLKQAQSIKSQNSLQEKLAQEKSrvadaeEKILELQQKLEHAHKVCLTDTCILEKKQLEERIK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1310 AKIRADAERQVQIIEERNKDLII--KYNETREQLYRLETEKVERESTLRQLQ---QELADALKKLSMSEASLEVITRYRN 1384
Cdd:pfam15742 162 EASENEAKLKQQYQEEQQKRKLLdqNVNELQQQVRSLQDKEAQLEMTNSQQQlriQQQEAQLKQLENEKRKSDEHLKSNQ 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1385 DIEGEKQILQKEVEKFRIKVQDLEEQC-----NQAERLHHQLKNLLEDKEREVMAVSQKvqeyssaaagdENAIKELEGH 1459
Cdd:pfam15742 242 ELSEKLSSLQQEKEALQEELQQVLKQLdvhvrKYNEKHHHHKAKLRRAKDRLVHEVEQR-----------DERIKQLENE 310
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1774923325 1460 VQKLEIENAKFEATAKQQAGQIDILQKELRETLSIRHKLEELI------ASLQSSKMGLEEKLNHQVHKQTA 1525
Cdd:pfam15742 311 IGILQQQSEKEKAFQKQVTAQNEILLLEKRKLLEQLTEQEELIknnkrtISSVQNRVNFLDEENKQLQENTL 382
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
829-1110 |
2.79e-04 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 45.79 E-value: 2.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 829 TPTLPFRNAKMLIEQLGVDSQDSVNLLKFQNIIHEYeRTIQRENGRYKLLASKVKKMENEKKDLQQIAEKNRELKSMLDH 908
Cdd:pfam05667 205 VPSLLERNAAELAAAQEWEEEWNSQGLASRLTPEEY-RKRKRTKLLKRIAEQLRSAALAGTEATSGASRSAQDLAELLSS 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 909 QKVESESDLN---------SLRFTLKQEEEKRKNAEMLYGKSQEQLRRKEDQCCQEMEAK-QLLELTIRNLELEMRSMQN 978
Cdd:pfam05667 284 FSGSSTTDTGltkgsrfthTEKLQFTNEAPAATSSPPTKVETEEELQQQREEELEELQEQlEDLESSIQELEKEIKKLES 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 979 TVRQVEEERNEVQRLlshehNARIAQEdilNNIRRKSEEIenekmwTKNAEvhGQLSK----IDEREKDLIlqnsNLQEE 1054
Cdd:pfam05667 364 SIKQVEEELEELKEQ-----NEELEKQ---YKVKKKTLDL------LPDAE--ENIAKlqalVDASAQRLV----ELAGQ 423
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1774923325 1055 MN----VLKLELDHVRSQNQQEESKY---MDENENLKEKIADLRRDLKMNEETLTQTVIQYNS 1110
Cdd:pfam05667 424 WEkhrvPLIEEYRALKEAKSNKEDESqrkLEEIKELREKIKEVAEEAKQKEELYKQLVAEYER 486
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1389-1843 |
3.08e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.91 E-value: 3.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1389 EKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKnLLEDKEREVMAVSQKVQEYSSAAAGDENAIKELEGHVQKLEIENA 1468
Cdd:COG4717 48 LERLEKEADELFKPQGRKPELNLKELKELEEELK-EAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1469 KFEATAKQQAG--QIDILQKELREtlsIRHKLEELIASLQSSKMGLEEKLNHQVHKQTALSQSAQDSHNLWEEELKSRSR 1546
Cdd:COG4717 127 LLPLYQELEALeaELAELPERLEE---LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEE 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1547 LGIRLAELEHEKAEFADQVESEKKKVKKLIEHKRSMEARfdQEIKRNAELQRDISGLKKLLKTAKKKIKELESVGTQQST 1626
Cdd:COG4717 204 LQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE--ERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFL 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1627 QDGFKSTHFE----KEIDIMKLKEKINELSFRLENESSNYKQ-LEAANRDLQQQLSSMKMFHKSQEHLEKGKRQLEDEVA 1701
Cdd:COG4717 282 VLGLLALLFLllarEKASLGKEAEELQALPALEELEEEELEElLAALGLPPDLSPEELLELLDRIEELQELLREAEELEE 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1702 NLKRQIEINKVDQSLIEKHKREIEErgrleLKQKLEEVNLFLQSQAASQETLEQIRAANDASVRNQMEHRIQELESDLGK 1781
Cdd:COG4717 362 ELQLEELEQEIAALLAEAGVEDEEE-----LRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEE 436
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1774923325 1782 IKNAQQENMLQRESTQTELERFKELyNEELKNRNSLAlKLERSNERLADANAKLLNERQRTK 1843
Cdd:COG4717 437 LEEELEELEEELEELREELAELEAE-LEQLEEDGELA-ELLQELEELKAELRELAEEWAALK 496
|
|
| PHA02946 |
PHA02946 |
ankyin-like protein; Provisional |
151-227 |
3.13e-04 |
|
ankyin-like protein; Provisional
Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 45.43 E-value: 3.13e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1774923325 151 KQLLEHGANINAFNKEGCTPLILAVTENNEEMVEFLLKEGADINACDRGGRTSLMISSNNGQNNLVRI--LLQNEADIN 227
Cdd:PHA02946 56 EELLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLYYLSGTDDEVIERInlLVQYGAKIN 134
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1671-1851 |
4.06e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.15 E-value: 4.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1671 DLQQQLSSMKMFHKSQEHLEKGKRQLEDEVANLKRQIEINKVDQSLIEKHKREIEErgrlelkqKLEEVNlflQSQAASQ 1750
Cdd:COG1579 11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLEL--------EIEEVE---ARIKKYE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1751 ETLEQIRAANDAsvrNQMEHRIQELESDLGKIKNAQQENMLQRESTQTELERFKELYNEELKNRNSLALKLERSNERLAD 1830
Cdd:COG1579 80 EQLGNVRNNKEY---EALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEA 156
|
170 180
....*....|....*....|.
gi 1774923325 1831 ANAKLLNERQRTKSLIASSIM 1851
Cdd:COG1579 157 ELEELEAEREELAAKIPPELL 177
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
166-195 |
4.68e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 39.16 E-value: 4.68e-04
10 20 30
....*....|....*....|....*....|
gi 1774923325 166 EGCTPLILAVTENNEEMVEFLLKEGADINA 195
Cdd:pfam13606 1 DGNTPLHLAARNGRLEIVKLLLENGADINA 30
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
838-1275 |
4.90e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 45.34 E-value: 4.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 838 KMLIEQLGVDSQDSVNLLKFQNIIHEYERTIQRENGRYKLLASKVKKMENEKKDLQQIAEKNRELKSMLDHQKVESESDL 917
Cdd:TIGR00618 382 HTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHL 461
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 918 NSLRFTLKQEEEKRKNAEMLYGKSQEQLRRKEDQCCQEMEAKQLLELTIRNLELEMRSMQN---TVRQVEEERNEVQRLL 994
Cdd:TIGR00618 462 QESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNpgpLTRRMQRGEQTYAQLE 541
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 995 SHEHNARIAQEDILNNIRRKSEEIENEK--------MWTKNAEVHGQLSKIDEREKDLILQNSNLqEEMNVLKLELDHVR 1066
Cdd:TIGR00618 542 TSEEDVYHQLTSERKQRASLKEQMQEIQqsfsiltqCDNRSKEDIPNLQNITVRLQDLTEKLSEA-EDMLACEQHALLRK 620
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1067 SQNQQEESKYMDENENLKEKIADLRRDLKMNEETLTQTVIQYNS----QLHALKTE-NTMLCSKLEHEKQGKDRLETELE 1141
Cdd:TIGR00618 621 LQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHAlsirVLPKELLAsRQLALQKMQSEKEQLTYWKEMLA 700
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1142 SIRSRLTSTLQEVERNQALKIEVERTLQRERDEWLRSQDKLNHELSTIRENNNNLSQQLIRAETKSNSLENELRQTNTSL 1221
Cdd:TIGR00618 701 QCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAEL 780
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 1774923325 1222 QDKVILSESTQRELTHTCGRIKELEHTLQLE-KDKICKSTVKQESLQEKLAQIQS 1275
Cdd:TIGR00618 781 SHLAAEIQFFNRLREEDTHLLKTLEAEIGQEiPSDEDILNLQCETLVQEEEQFLS 835
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
1330-1681 |
5.08e-04 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 44.67 E-value: 5.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1330 LIIKYNETREQLYRLETEKVERESTLRQ-------LQQELADALKKLSMSEASLEVITRYRNDIEGEKQILQKEVEKFRI 1402
Cdd:pfam19220 32 LIEPIEAILRELPQAKSRLLELEALLAQeraaygkLRRELAGLTRRLSAAEGELEELVARLAKLEAALREAEAAKEELRI 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1403 KVQDLEEQCNQAERlhhQLKnlLEDKEREvmAVSQKVQEYSSAAAGDENAIKELEGHVQK-------LEIENAKFEATAK 1475
Cdd:pfam19220 112 ELRDKTAQAEALER---QLA--AETEQNR--ALEEENKALREEAQAAEKALQRAEGELATarerlalLEQENRRLQALSE 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1476 QQAGQIDILQKELRETLSIRHKLEELIASLQSSKMG---LEEKLNHQVHKQTALSQSAQDSHNLWEEELKSRS----RLG 1548
Cdd:pfam19220 185 EQAAELAELTRRLAELETQLDATRARLRALEGQLAAeqaERERAEAQLEEAVEAHRAERASLRMKLEALTARAaateQLL 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1549 IRLAELEHEKAEfaDQVESEKKKVKKLIEHKRSMearfdqeiKRNAELQRDISGLKKLLKTAKKKIKELESVGTQQSTQD 1628
Cdd:pfam19220 265 AEARNQLRDRDE--AIRAAERRLKEASIERDTLE--------RRLAGLEADLERRTQQFQEMQRARAELEERAEMLTKAL 334
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 1774923325 1629 GFKSTHFEK-EIDIMKLKEKINELSFRLENESSNykqLEAANRDLQQQLSSMKM 1681
Cdd:pfam19220 335 AAKDAALERaEERIASLSDRIAELTKRFEVERAA---LEQANRRLKEELQRERA 385
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1538-1847 |
5.44e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 45.05 E-value: 5.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1538 EEELKSRSRLGIRLAELEHEKAEFADQVESEKKKVKKLIEHKRSMEARFDQEIKRNAELQRDISGLKKLLKTAKKKIKEL 1617
Cdd:PRK03918 199 EKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEEL 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1618 ESVGTQQSTQDGFKsthfEKEIDIMKLKEKINELSFRLENESSNYKQLEAANRDLQQQLSSMKmfhKSQEHLEKGKRQLE 1697
Cdd:PRK03918 279 EEKVKELKELKEKA----EEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKE---ERLEELKKKLKELE 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1698 DEVANLK---RQIEINKVDQSLIEKHKREIEERGRLELKQKLEEVnlflqsQAASQETLEQIRAANDAsvRNQMEHRIQE 1774
Cdd:PRK03918 352 KRLEELEerhELYEEAKAKKEELERLKKRLTGLTPEKLEKELEEL------EKAKEEIEEEISKITAR--IGELKKEIKE 423
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1774923325 1775 LESDLGKIKNAQQENML-QRESTQTELERFKELYNEELKNRNSLALKLERSNERLADANAKLLNERQRTKSLIA 1847
Cdd:PRK03918 424 LKKAIEELKKAKGKCPVcGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIK 497
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
838-1487 |
6.12e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 45.04 E-value: 6.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 838 KMLIEQLGVDSQDSVNLLKFQNIIHEYERTIQR--ENGRYKLLASKVKKMENEKKDLQQIAEKNRELKSMLDHQKVeses 915
Cdd:TIGR00606 457 KFVIKELQQLEGSSDRILELDQELRKAERELSKaeKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTT---- 532
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 916 dlnslrfTLKQEEEKRKNAEMLYgksqEQLRRKEDQCCQEMEAKQLLELTIRNLELEMRSMQNTVRQVEEERNEVQRLLS 995
Cdd:TIGR00606 533 -------TRTQMEMLTKDKMDKD----EQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELA 601
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 996 hehnariAQEDILNNIRRKSEEIENekmwtknaevhgQLSKIDEREKDLilqnsnlqeemnvlkleldhvrSQNQQEESK 1075
Cdd:TIGR00606 602 -------SLEQNKNHINNELESKEE------------QLSSYEDKLFDV----------------------CGSQDEESD 640
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1076 YmdenENLKEKIADLRRDLKMneetLTQTVIQYNSQLHALKTENTMLCSKLEHEKQGKDRLETELESIRSRLTSTLQEVE 1155
Cdd:TIGR00606 641 L----ERLKEEIEKSSKQRAM----LAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLK 712
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1156 RNQALKieveRTLQRERDEWL-------RSQDKLNHELSTIRENNNNLSQQLIRAETKSNSLENELRQTNTS------LQ 1222
Cdd:TIGR00606 713 STESEL----KKKEKRRDEMLglapgrqSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEeesakvCL 788
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1223 DKVILSESTQRELTHTCGRIKELEHTLQLEKDKICKSTVKQE--SLQEKLAQIQSENMLLRQQIEDVNNKGIIKDKTVSD 1300
Cdd:TIGR00606 789 TDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEkqEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNE 868
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1301 VQD---KFTEIIAKIRADAERQVQIIEERnKDLIIKYNETREQLYRLETEK----VERESTLRQLQQELADALKKLSMSE 1373
Cdd:TIGR00606 869 LKSeklQIGTNLQRRQQFEEQLVELSTEV-QSLIREIKDAKEQDSPLETFLekdqQEKEELISSKETSNKKAQDKVNDIK 947
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1374 ASLEVITRYRNDIEG------EKQILQKEVEKFRIKVQdLEEQCNQAERLHHQLKNLLEDKErevmavSQKVQEyssAAA 1447
Cdd:TIGR00606 948 EKVKNIHGYMKDIENkiqdgkDDYLKQKETELNTVNAQ-LEECEKHQEKINEDMRLMRQDID------TQKIQE---RWL 1017
|
650 660 670 680
....*....|....*....|....*....|....*....|
gi 1774923325 1448 GDENAIKELEGHVQKLEIENAKFEatakQQAGQIDILQKE 1487
Cdd:TIGR00606 1018 QDNLTLRKRENELKEVEEELKQHL----KEMGQMQVLQMK 1053
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1081-1566 |
6.25e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.76 E-value: 6.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1081 ENLKEKIADLRRDLKMNEETLTQTVIQYNSQLHALKTENtmlcSKLEHEKQGKDRLETELESIRSRLTSTLQEVERNQAL 1160
Cdd:COG4717 49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKE----EEYAELQEELEELEEELEELEAELEELREELEKLEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1161 K-----IEVERTLQRERDEWLRSQDKLNHELSTIRENNNNLSQQLIRAETKSNSLENELRQTntslqdkvilSESTQREL 1235
Cdd:COG4717 125 LqllplYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQL----------SLATEEEL 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1236 THTCGRIKELEhtlqlekdkickstVKQESLQEKLAQIQSENMLLRQQIEDVNNKGIIKDKTVSDVQDKFTEIIAKIRAD 1315
Cdd:COG4717 195 QDLAEELEELQ--------------QRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLA 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1316 AERQVQIIEErNKDLIIKYNETREQLYRLETEKVERESTLRQLQQELADALKKLSMSEAslEVITRYRNDIEGEKQILQK 1395
Cdd:COG4717 261 LLGLGGSLLS-LILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEE--EELEELLAALGLPPDLSPE 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1396 EVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKEREvmavsqkvQEYSSAAAGDENAIKELEGHVQKLEIENAKFEAtAK 1475
Cdd:COG4717 338 ELLELLDRIEELQELLREAEELEEELQLEELEQEIA--------ALLAEAGVEDEEELRAALEQAEEYQELKEELEE-LE 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1476 QQAGQIDILQKELRETLS---IRHKLEELIASLQSskmgLEEKLNHQVHKQTALSQSAqdshnlweEELKSRSRLGIRLA 1552
Cdd:COG4717 409 EQLEELLGELEELLEALDeeeLEEELEELEEELEE----LEEELEELREELAELEAEL--------EQLEEDGELAELLQ 476
|
490
....*....|....
gi 1774923325 1553 ELEHEKAEFADQVE 1566
Cdd:COG4717 477 ELEELKAELRELAE 490
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
966-1595 |
6.93e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.91 E-value: 6.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 966 IRNLELEMRSMQNTVRQVeeeRNEVQRLLSHEHNARIAQE--DILNNIRRKSEEIEneKMWTKNAEVHGQLSKID----E 1039
Cdd:COG4913 213 VREYMLEEPDTFEAADAL---VEHFDDLERAHEALEDAREqiELLEPIRELAERYA--AARERLAELEYLRAALRlwfaQ 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1040 REKDLiLQN--SNLQEEMNVLKLELDHVRSQNQQEESKY------MDEN-----ENLKEKIADLRRDLkmneETLTQTVI 1106
Cdd:COG4913 288 RRLEL-LEAelEELRAELARLEAELERLEARLDALREELdeleaqIRGNggdrlEQLEREIERLEREL----EERERRRA 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1107 QYNSQLHALKTEntmlcskLEHEKQGKDRLETELESIRSRLTSTLQEVERNQALKIEVERTLQRERDEwlrsqdkLNHEL 1186
Cdd:COG4913 363 RLEALLAALGLP-------LPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRE-------LEAEI 428
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1187 STIRENNNNLSQQLIRA----------------------------ETKSNSLENELRQTNTSLqdkvILSESTQRELTHT 1238
Cdd:COG4913 429 ASLERRKSNIPARLLALrdalaealgldeaelpfvgelievrpeeERWRGAIERVLGGFALTL----LVPPEHYAAALRW 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1239 CGRIKeLEHTLQLEK-----DKICKSTVKQESLQEKLAQIQSE-----NMLLRQQ--------IEDVNN--KGIIKDKTV 1298
Cdd:COG4913 505 VNRLH-LRGRLVYERvrtglPDPERPRLDPDSLAGKLDFKPHPfrawlEAELGRRfdyvcvdsPEELRRhpRAITRAGQV 583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1299 SDVQDKFteiiAKIRADAERQVQIIEERNKDLIikyNETREQLYRLETEKVERESTLRQLQQELaDALKKLSMSEASLEV 1378
Cdd:COG4913 584 KGNGTRH----EKDDRRRIRSRYVLGFDNRAKL---AALEAELAELEEELAEAEERLEALEAEL-DALQERREALQRLAE 655
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1379 ITRYRNDIEGekqiLQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLledkEREVMAVSQKVQEYSSAAAGDENAIKELEG 1458
Cdd:COG4913 656 YSWDEIDVAS----AEREIAELEAELERLDASSDDLAALEEQLEEL----EAELEELEEELDELKGEIGRLEKELEQAEE 727
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1459 HVQKLEIENAkfEATAKQQAGQIDILQKELREtLSIRHKLEELIASLQSSKMGLEEKLNhqvHKQTALSQSAQDSHNLWE 1538
Cdd:COG4913 728 ELDELQDRLE--AAEDLARLELRALLEERFAA-ALGDAVERELRENLEERIDALRARLN---RAEEELERAMRAFNREWP 801
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 1774923325 1539 EELksrSRLGIRLAELEHEKAEFADQVESEkkkvkkLIEHkrsmEARFDQEIKRNAE 1595
Cdd:COG4913 802 AET---ADLDADLESLPEYLALLDRLEEDG------LPEY----EERFKELLNENSI 845
|
|
| PHA02946 |
PHA02946 |
ankyin-like protein; Provisional |
62-231 |
7.91e-04 |
|
ankyin-like protein; Provisional
Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 44.27 E-value: 7.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 62 NQLDKENRTPLHIACANGQLDTVKVLLEHKSKLNLCDNDNRSPLLKAIQCQQESCATV--LLEHNAD-PNLVDINGNAAL 138
Cdd:PHA02946 66 NETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLYYLSGTDDEVIERInlLVQYGAKiNNSVDEEGCGPL 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 139 hLAALIPSVSIAKQLLEHGANINAFNKEGCTPLILAVTENNEE--MVEFLLKEGADINACDRGGRTSLMISSNNGQNNLV 216
Cdd:PHA02946 146 -LACTDPSERVFKKIMSIGFEARIVDKFGKNHIHRHLMSDNPKasTISWMMKLGISPSKPDHDGNTPLHIVCSKTVKNVD 224
|
170
....*....|....*.
gi 1774923325 217 RI-LLQNEADINIKDE 231
Cdd:PHA02946 225 IInLLLPSTDVNKQNK 240
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1631-1835 |
9.39e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.99 E-value: 9.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1631 KST--HFEKEIDIMKLKEKINEL-SFRLENESSNYKQLEAANRDLQQQLSSMKMFHKSQEHLEkgkrQLEDEVANLKRQI 1707
Cdd:COG4717 36 KSTllAFIRAMLLERLEKEADELfKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELE----ELEEELEELEAEL 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1708 EINKVDQSLIEKHKREIEERGRLE-LKQKLEEVnlflqsqaasQETLEQIRAANDAsvRNQMEHRIQELESDLGKIKNA- 1785
Cdd:COG4717 112 EELREELEKLEKLLQLLPLYQELEaLEAELAEL----------PERLEELEERLEE--LRELEEELEELEAELAELQEEl 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1786 QQENMLQRESTQTELERFKELYNEELKNRNSLALKLERSNERLADANAKL 1835
Cdd:COG4717 180 EELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEL 229
|
|
| trp |
TIGR00870 |
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ... |
70-187 |
1.21e-03 |
|
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 43.92 E-value: 1.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 70 TPLHIACANGQLDTVKVLLEHKSKLNL--CDND------------NRSPLLKAIQCQQESCATVLLEHNADPNLVDINGN 135
Cdd:TIGR00870 130 TALHLAAHRQNYEIVKLLLERGASVPAraCGDFfvksqgvdsfyhGESPLNAAACLGSPSIVALLSEDPADILTADSLGN 209
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1774923325 136 AALHLAALIPSVSI------------AKQLLEHGANINAF----NKEGCTPLILAVTENNEEMVEFLL 187
Cdd:TIGR00870 210 TLLHLLVMENEFKAeyeelscqmynfALSLLDKLRDSKELevilNHQGLTPLKLAAKEGRIVLFRLKL 277
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
1037-1341 |
1.29e-03 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 43.69 E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1037 IDEREKDLILQNSN------LQEEMNVLKLELDHVRSQNQQEESKYMDENENLKEKI----------ADLRRDLKM-NEE 1099
Cdd:PLN03229 464 IEKLKKEIDLEYTEaviamgLQERLENLREEFSKANSQDQLMHPVLMEKIEKLKDEFnkrlsrapnyLSLKYKLDMlNEF 543
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1100 TLTQTVIQYNSQLHALKTENTMLCSKLEHEKQGKDRLETELESIRSRLTSTLQEVerNQALKIEVERTLQRERDEWLRSQ 1179
Cdd:PLN03229 544 SRAKALSEKKSKAEKLKAEINKKFKEVMDRPEIKEKMEALKAEVASSGASSGDEL--DDDLKEKVEKMKKEIELELAGVL 621
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1180 DKLNHELSTIRENNNNLSQQLIRAETKSNsLENELRQTNTSLQDKVilsestqrelthtcgRIKELEHTLQLEKDKICK- 1258
Cdd:PLN03229 622 KSMGLEVIGVTKKNKDTAEQTPPPNLQEK-IESLNEEINKKIERVI---------------RSSDLKSKIELLKLEVAKa 685
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1259 STVKQESLQEKLAQIQSEnmlLRQQIEDVNNkgiikdktVSDVQDKFTEIIAKIRADAERQV----QIIEERNKDLIIKY 1334
Cdd:PLN03229 686 SKTPDVTEKEKIEALEQQ---IKQKIAEALN--------SSELKEKFEELEAELAAARETAAesngSLKNDDDKEEDSKE 754
|
....*..
gi 1774923325 1335 NETREQL 1341
Cdd:PLN03229 755 DGSRVEV 761
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
183-255 |
1.34e-03 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 43.73 E-value: 1.34e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1774923325 183 VEFLLKEGADINACDRGGRTSLMISSNNGQNNLVRILLQNEADINIKDEKSWTADDYGVMNGHHACSHLIIEH 255
Cdd:PTZ00322 98 ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRH 170
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
866-1342 |
1.40e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.60 E-value: 1.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 866 RTIQRENGRYKLLASKVKKMENEKKDLQQIAEKNRELKSMLDHQK--VESESDLNSLRFTLKQEEEKRKNAEMLYGKSQE 943
Cdd:COG4717 81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLqlLPLYQELEALEAELAELPERLEELEERLEELRE 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 944 QLRRKEDQCCQEMEAKQLLELTIRNLELEMRsmqntvRQVEEERNEVQRLLSHEHNARIAQEDILNNIRRKSEEIENekm 1023
Cdd:COG4717 161 LEEELEELEAELAELQEELEELLEQLSLATE------EELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ--- 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1024 WTKNAEVHGQLSKIDEREKDLIL-------------QNSNLQEEMNVLKLEL------------DHVRSQNQQEESKYMD 1078
Cdd:COG4717 232 LENELEAAALEERLKEARLLLLIaaallallglggsLLSLILTIAGVLFLVLgllallflllarEKASLGKEAEELQALP 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1079 ENENL-KEKIADLRRDLKMNEETLTQTVIQYNSQLHALKTENTMLcSKLEHEKQgKDRLETELESIRSRLTSTlQEVERN 1157
Cdd:COG4717 312 ALEELeEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREA-EELEEELQ-LEELEQEIAALLAEAGVE-DEEELR 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1158 QALKIevertlQRERDEWLRSQDKLNHELSTIRENNNNLSQQLIRAEtksnsLENELRQTNTSLQDKVILSESTQRELTH 1237
Cdd:COG4717 389 AALEQ------AEEYQELKEELEELEEQLEELLGELEELLEALDEEE-----LEEELEELEEELEELEEELEELREELAE 457
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1238 TCGRIKELEHTLQLEKDKIckstvKQESLQEKLAQIQSE---NMLLRQQIEDVnnKGIIKDKTVSDVQDKFTEIIAKIRA 1314
Cdd:COG4717 458 LEAELEQLEEDGELAELLQ-----ELEELKAELRELAEEwaaLKLALELLEEA--REEYREERLPPVLERASEYFSRLTD 530
|
490 500 510
....*....|....*....|....*....|....*...
gi 1774923325 1315 DAERQVQIIE------ERNKDLIIKYNE----TREQLY 1342
Cdd:COG4717 531 GRYRLIRIDEdlslkvDTEDGRTRPVEElsrgTREQLY 568
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
38-165 |
1.47e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 43.41 E-value: 1.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 38 SKLHRAASAGDVGKIKQLIKKQDiNQLDKENR--TPLHIACANGQldTVKVLLEHKSKLNLCDNDNRSPLLKAIQ--CQQ 113
Cdd:PHA02874 192 SPLHNAAEYGDYACIKLLIDHGN-HIMNKCKNgfTPLHNAIIHNR--SAIELLINNASINDQDIDGSTPLHHAINppCDI 268
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1774923325 114 ESCATvLLEHNADPNLVDINGNAALHLA-ALIPSVSIAKQLLEHGANINAFNK 165
Cdd:PHA02874 269 DIIDI-LLYHKADISIKDNKGENPIDTAfKYINKDPVIKDIIANAVLIKEADK 320
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
868-1053 |
1.55e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 43.59 E-value: 1.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 868 IQRENGRYKLLASKVKKMENEKKDLQQIAEKNRELKSMLDHQKVESESDLNSLRFTLKQEEEKRKNAEMLYGKSQEQLRR 947
Cdd:PTZ00121 1625 LKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKA 1704
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 948 KEDQCCQEMEAKQLLELTIRNLELEMRSMQNTVRQVEEERNEVQRLLSHEHNARIAQedILNNIRRKSEEIENEKMWTKN 1027
Cdd:PTZ00121 1705 EELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAH--LKKEEEKKAEEIRKEKEAVIE 1782
|
170 180 190
....*....|....*....|....*....|
gi 1774923325 1028 AEV----HGQLSKIDEREKDLILQNSNLQE 1053
Cdd:PTZ00121 1783 EELdeedEKRRMEVDKKIKDIFDNFANIIE 1812
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
1061-1531 |
1.57e-03 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 43.52 E-value: 1.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1061 ELDHVRSQNQQEESKYMDENENLKEKIAdlrrDLKMNEETLTQTVIQYN---SQLHALKTENTMLCSKLEHEKQGKDRLE 1137
Cdd:pfam05622 18 ELDQQVSLLQEEKNSLQQENKKLQERLD----QLESGDDSGTPGGKKYLllqKQLEQLQEENFRLETARDDYRIKCEELE 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1138 TELESIRSR---LTSTLQEVernQALKIEVE--------------------RTLQRERDewLRSQDKLNHELSTI-RENN 1193
Cdd:pfam05622 94 KEVLELQHRneeLTSLAEEA---QALKDEMDilressdkvkkleatvetykKKLEDLGD--LRRQVKLLEERNAEyMQRT 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1194 NNLSQQLIRAETKSNSLENELRQTnTSLQDKviLSESTQR--ELTHTCGRIKELEHTLQLEKDKIcksTVKQESLQE--- 1268
Cdd:pfam05622 169 LQLEEELKKANALRGQLETYKRQV-QELHGK--LSEESKKadKLEFEYKKLEEKLEALQKEKERL---IIERDTLREtne 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1269 --KLAQIQS-----ENMLLRQQIEDVNNkgIIKDKTVSDVQDKFTEIIAKIRADAERQVQIIEERNKDLIIKYNETREQL 1341
Cdd:pfam05622 243 elRCAQLQQaelsqADALLSPSSDPGDN--LAAEIMPAEIREKLIRLQHENKMLRLGQEGSYRERLTELQQLLEDANRRK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1342 YRLETEKVERESTLRQLQQELADALKKLSMSEASLEVITRYRNDIEGEKQIL---QKEVEKFRIKVQDLE-EQCNQAERL 1417
Cdd:pfam05622 321 NELETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSLLKQKLEEHLEKLheaQSELQKKKEQIEELEpKQDSNLAQK 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1418 HHQLKNLLEDKEREVMAVSQKVQEYSSAAagdENAIKELEGHVQKLEI-ENAKFEATAKQQAGQIDILQKELRETLSIRH 1496
Cdd:pfam05622 401 IDELQEALRKKDEDMKAMEERYKKYVEKA---KSVIKTLDPKQNPASPpEIQALKNQLLEKDKKIEHLERDFEKSKLQRE 477
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 1774923325 1497 KLEELIAS------LQSSKMGLEEKL-NHQVHKQTALSQSAQ 1531
Cdd:pfam05622 478 QEEKLIVTawynmgMALHRKAIEERLaGLSSPGQSFLARQRQ 519
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
980-1233 |
1.77e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 43.41 E-value: 1.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 980 VRQVEEERNEVQRLLShEHNARIAQEDILNNIRRKSEEIENE-KMWTKNAEVHGQL----SKIDEREKDLILQNSNLQEE 1054
Cdd:COG5185 277 SKRLNENANNLIKQFE-NTKEKIAEYTKSIDIKKATESLEEQlAAAEAEQELEESKreteTGIQNLTAEIEQGQESLTEN 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1055 MNVLKLELDHVRSQNQQEESKYM-----DENENLKEKI----ADLRRDLKMNEETLTQTVIQYNSQLHALKTENTMLCSK 1125
Cdd:COG5185 356 LEAIKEEIENIVGEVELSKSSEEldsfkDTIESTKESLdeipQNQRGYAQEILATLEDTLKAADRQIEELQRQIEQATSS 435
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1126 LEHEKQGKDRLETELESIRSRLTSTLQE--VERNQALKIEVERTLQRERDEWLRSQDKLNHELSTIRENNNNLSQQLIRA 1203
Cdd:COG5185 436 NEEVSKLLNELISELNKVMREADEESQSrlEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGV 515
|
250 260 270
....*....|....*....|....*....|
gi 1774923325 1204 ETKSNSLENELRQTNTSLQDKVILSESTQR 1233
Cdd:COG5185 516 RSKLDQVAESLKDFMRARGYAHILALENLI 545
|
|
| TRPV1-4 |
cd22193 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 1-4; TRPV1-4 are ... |
78-214 |
1.89e-03 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 1-4; TRPV1-4 are thermo-sensing channels that function directly in temperature-sensing and nociception; they share substantial structural and functional properties. Transient Receptor Potential (TRP) ion channels activated by temperature (thermo TRPs) are important molecular players in acute, inflammatory, and chronic pain states. So far, 11 TRP channels in mammalian cells have been identified as thermosensitive TRP (thermo-TRP) channels. TRPV1-4 channels are activated by different heat temperatures, for example, TRPV1 and TRPV2 are activated by high temperatures (>43C and >55C, respectively). TRPV1-4 belong to the vanilloid TRP subfamily (TRPV), named after the founding member vanilloid receptor 1 (TRPV1). The structure of TRPV shows the typical topology features of all TRP ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains.
Pssm-ID: 411977 [Multi-domain] Cd Length: 607 Bit Score: 43.25 E-value: 1.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 78 NGQLDTVKVLLEHKSKlnlcdNDNRSPLLKAiQCQQEScatvllehnadpnlvdINGNAALHLAALIPSVSIAKQLLEHG 157
Cdd:cd22193 42 PGTNDTIRILLDIAEK-----TDNLKRFINA-EYTDEY----------------YEGQTALHIAIERRQGDIVALLVENG 99
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1774923325 158 ANINA------FNKE--------GCTPLILAVTENNEEMVEFLLK---EGADINACDRGGRTSL----MISSNNGQNN 214
Cdd:cd22193 100 ADVHAhakgrfFQPKyqgegfyfGELPLSLAACTNQPDIVQYLLEnehQPADIEAQDSRGNTVLhalvTVADNTKENT 177
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1126-1778 |
1.97e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.37 E-value: 1.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1126 LEHEKQGKDRLEtELESIRSRLTSTLQEVERNQALKIEVER-TLQRERDEWLRSQDKLNHELSTIRENNNNLSQQLIRAE 1204
Cdd:COG4913 244 LEDAREQIELLE-PIRELAERYAAARERLAELEYLRAALRLwFAQRRLELLEAELEELRAELARLEAELERLEARLDALR 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1205 TKSNSLENELRQTNTslqdkvilsestqrelthtcGRIKELEHTLqlekdkickstvkqESLQEKLAQIQSENMLLRQQI 1284
Cdd:COG4913 323 EELDELEAQIRGNGG--------------------DRLEQLEREI--------------ERLERELEERERRRARLEALL 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1285 EDVnnkgiikDKTVSDVQDKFTEIIAKIRADAERQVQIIEErnkdliikyneTREQLYRLETEKVERESTLRQLQQELAD 1364
Cdd:COG4913 369 AAL-------GLPLPASAEEFAALRAEAAALLEALEEELEA-----------LEEALAEAEAALRDLRRELRELEAEIAS 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1365 -ALKKLSMSEASLEVitryRNDIEGEKQILQKEVeKF---RIKVQDLEEQC-NQAERLHHQLK-NLL--EDKEREVMA-- 1434
Cdd:COG4913 431 lERRKSNIPARLLAL----RDALAEALGLDEAEL-PFvgeLIEVRPEEERWrGAIERVLGGFAlTLLvpPEHYAAALRwv 505
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1435 ---------VSQKVQEYSSAAAG---DENAIkeleghVQKLEIENAKFEATAKQQ------------------------- 1477
Cdd:COG4913 506 nrlhlrgrlVYERVRTGLPDPERprlDPDSL------AGKLDFKPHPFRAWLEAElgrrfdyvcvdspeelrrhpraitr 579
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1478 AGQ-----------------------------IDILQKELRETLSIRHKLEELIASLQSSKMGLEEKLN-HQVHKQTALS 1527
Cdd:COG4913 580 AGQvkgngtrhekddrrrirsryvlgfdnrakLAALEAELAELEEELAEAEERLEALEAELDALQERREaLQRLAEYSWD 659
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1528 Q----SAQDSHNLWEEELKSRSRLGIRLAELEHEkaefADQVESEKKKVKKLIEHKRSMEARFDQEIKRNAELQRDISG- 1602
Cdd:COG4913 660 EidvaSAEREIAELEAELERLDASSDDLAALEEQ----LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDr 735
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1603 -LKKLLKTAKKKIKELESVGTQQSTQDGFKSTHFEKEIDIMKLKEKINELSFRLENESSNYKQL-EAANRDLQQQLSS-- 1678
Cdd:COG4913 736 lEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREwPAETADLDADLESlp 815
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1679 --MKMFHKSQ-----EHLEKGKRQL----EDEVANLKRQIE---------INKVDQSL------------IEKHKREIEE 1726
Cdd:COG4913 816 eyLALLDRLEedglpEYEERFKELLnensIEFVADLLSKLRraireikerIDPLNDSLkripfgpgrylrLEARPRPDPE 895
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1774923325 1727 RGRL--ELKQKLEEVNLFLQSQAASQET-----LEQIRAANDAS----------VRNQMEHRIQELESD 1778
Cdd:COG4913 896 VREFrqELRAVTSGASLFDEELSEARFAalkrlIERLRSEEEESdrrwrarvldVRNHLEFDAEEIDRE 964
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
1246-1848 |
2.12e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 43.24 E-value: 2.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1246 EHTLQLEKDKICKSTVKQESLQEKLAQIQSENMLLRQQIEDVNNKGIIKDKTVSDVQDKFTEIiAKIRADAERQVQIIEE 1325
Cdd:pfam01576 11 EEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQEL-EEILHELESRLEEEEE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1326 RNKDLIIKYNETREQLYRLETEKVERESTLRQLQQELADALKKLSMSEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQ 1405
Cdd:pfam01576 90 RSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLA 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1406 DLEEQCNQAERLHHQLKNLL---------EDKEREVMAVSQKVQEYSSAAAGDENA-----IKELEGHVQKLEIENAKFE 1471
Cdd:pfam01576 170 EEEEKAKSLSKLKNKHEAMIsdleerlkkEEKGRQELEKAKRKLEGESTDLQEQIAelqaqIAELRAQLAKKEEELQAAL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1472 ATAKQQAGQIDILQKELRETLSIRHKLEELIAS------------------LQSSKMGLEEKLNHQVHKQTALSQSAQDS 1533
Cdd:pfam01576 250 ARLEEETAQKNNALKKIRELEAQISELQEDLESeraarnkaekqrrdlgeeLEALKTELEDTLDTTAAQQELRSKREQEV 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1534 HNL---WEEELKSRSrlgIRLAEL--EHEKA--EFADQVESEKKKVKKLIEHKRSMEarfdqeiKRNAELQRDISGLKKL 1606
Cdd:pfam01576 330 TELkkaLEEETRSHE---AQLQEMrqKHTQAleELTEQLEQAKRNKANLEKAKQALE-------SENAELQAELRTLQQA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1607 LKTAKKKIKELESvgtqqSTQDgFKSTHFEKEIDIMKLKEKINELSFRLENESSNYKQLEAANRDLQQQLSSMK-MFHKS 1685
Cdd:pfam01576 400 KQDSEHKRKKLEG-----QLQE-LQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLEsQLQDT 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1686 QEHLEKGKRQ----------LEDEVANLKRQIEINKVDQSLIEKHKREIEERgRLELKQKLEEVnlflqsqAASQETLEQ 1755
Cdd:pfam01576 474 QELLQEETRQklnlstrlrqLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQ-LSDMKKKLEED-------AGTLEALEE 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1756 IRaandasvrnqmehriqelesdlgkiknaqqeNMLQREStqtelerfkELYNEELKNRNSLALKLERSNERLADANAKL 1835
Cdd:pfam01576 546 GK-------------------------------KRLQREL---------EALTQQLEEKAAAYDKLEKTKNRLQQELDDL 585
|
650
....*....|...
gi 1774923325 1836 LNERQRTKSLIAS 1848
Cdd:pfam01576 586 LVDLDHQRQLVSN 598
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
133-162 |
2.21e-03 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 37.24 E-value: 2.21e-03
10 20 30
....*....|....*....|....*....|
gi 1774923325 133 NGNAALHLAALIPSVSIAKQLLEHGANINA 162
Cdd:pfam13606 1 DGNTPLHLAARNGRLEIVKLLLENGADINA 30
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
1224-1846 |
2.63e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.11 E-value: 2.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1224 KVILSESTQRELTHTCGR-IKELEHTLQLEKDKICKSTVKQESLQEKLAQIQSENMLLRQQiEDVNNKGIIKDKTVSDVQ 1302
Cdd:TIGR00606 183 RYIKALETLRQVRQTQGQkVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSY-ENELDPLKNRLKEIEHNL 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1303 DKFTEIIAKIRADAERQVQIiEERNKDLIIK----YNETREQLYRLETEkveRESTLRQLQQELADALKKLSMSEASLEV 1378
Cdd:TIGR00606 262 SKIMKLDNEIKALKSRKKQM-EKDNSELELKmekvFQGTDEQLNDLYHN---HQRTVREKERELVDCQRELEKLNKERRL 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1379 ITRYRNDIEGE--KQILQKEVEKFRIKVQDLEEQCNQaerLHHQLKNLLEDK--EREVMAVSQKVQEYSSAAAGDENaik 1454
Cdd:TIGR00606 338 LNQEKTELLVEqgRLQLQADRHQEHIRARDSLIQSLA---TRLELDGFERGPfsERQIKNFHTLVIERQEDEAKTAA--- 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1455 eleghvqKLEIENAKFEATAKQQAGQIDILQKELRETLsirhkleeliaslQSSKMGLEEKLNHQVHKQTALSQSAQDSH 1534
Cdd:TIGR00606 412 -------QLCADLQSKERLKQEQADEIRDEKKGLGRTI-------------ELKKEILEKKQEELKFVIKELQQLEGSSD 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1535 NLWEEELKsrsrlgIRLAELEHEKAEFADQVESEKKKVKKLIEHKRSMEARFDQEIKRNAELQRDisglkkllktaKKKI 1614
Cdd:TIGR00606 472 RILELDQE------LRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHH-----------TTTR 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1615 KELESVGTQQSTQD----GFKSTHFEKEIDIMKLKEKINELSFRLENESSNYKQLEAANRDLQQQLSSMKmfhKSQEHLE 1690
Cdd:TIGR00606 535 TQMEMLTKDKMDKDeqirKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLE---QNKNHIN 611
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1691 KGKRQLEDEVANLKRQIE---INKVDQSLIEKHKREIeERGRLELKQKLEEVNLFlqSQAASQETLEQIRAANDASVRNQ 1767
Cdd:TIGR00606 612 NELESKEEQLSSYEDKLFdvcGSQDEESDLERLKEEI-EKSSKQRAMLAGATAVY--SQFITQLTDENQSCCPVCQRVFQ 688
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1774923325 1768 MEHRIQELESDLGKIKNAQQENMLQRESTQTELERFKELYNEELKNRNSLALKLERSNERLADANAKLLNERQRTKSLI 1846
Cdd:TIGR00606 689 TEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDI 767
|
|
| PHA02741 |
PHA02741 |
hypothetical protein; Provisional |
123-219 |
2.69e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 165108 [Multi-domain] Cd Length: 169 Bit Score: 40.80 E-value: 2.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 123 HNADPNLVDINGNAALHLAALIPSVSIAKQLLEH----GANINAFNK-EGCTPLILAVTENNEEMVEFLLKE-GADINAC 196
Cdd:PHA02741 49 HAAALNATDDAGQMCIHIAAEKHEAQLAAEIIDHlielGADINAQEMlEGDTALHLAAHRRDHDLAEWLCCQpGIDLHFC 128
|
90 100
....*....|....*....|...
gi 1774923325 197 DRGGRTSLMISSNNGQNNLVRIL 219
Cdd:PHA02741 129 NADNKSPFELAIDNEDVAMMQIL 151
|
|
| Rab5-bind |
pfam09311 |
Rabaptin-like protein; Members of this family are predominantly found in Rabaptin and allow ... |
940-1235 |
2.86e-03 |
|
Rabaptin-like protein; Members of this family are predominantly found in Rabaptin and allow for binding to the GTPase Rab5. This interaction is necessary and sufficient for Rab5-dependent recruitment of Rabaptin5 to early endosomal membranes.
Pssm-ID: 462752 [Multi-domain] Cd Length: 307 Bit Score: 41.88 E-value: 2.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 940 KSQEQLRRKEDQCCQEMEAKQLLELTIRNLELEMRSMQNTV--RQVEEERNEVQRLLSHEHNARIAQEDiLNNIRRKSEE 1017
Cdd:pfam09311 27 KLQEMLRQANDQLEKTMKDKKELEDKMNQLSEETSNQVSTLakRNQKSETLLDELQQAFSQAKRNFQDQ-LAVLMDSREQ 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1018 IENE--KMWTKNAEVHGQ--LSKIDEREKDLILQNSNLQEEMNVLKL--ELDHVRSQNQQEESKYMDENENLKEKIADLR 1091
Cdd:pfam09311 106 VSDElvRLQKDNESLQGKhsLHVSLQQAEKFDMPDTVQELQELVLKYreELIEVRTAADHMEEKLKAEILFLKEQIQAEQ 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1092 RDLKMNEETLTQTVIQYNSQLHALKTENTMLcsklehekqgkDRLETELESIRSRLTSTLQEVERNQALKIEVERTLQRE 1171
Cdd:pfam09311 186 CLKENLEETLQAEIENCKEEIASISSLKVEL-----------ERIKAEKEQLENGLTEKIRQLEDLQTTKGSLETQLKKE 254
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1774923325 1172 RDEwlrsqdklnhelstirenNNNLSQQLIRAETKSNSLENELRQTNTSLQDKVILSESTQREL 1235
Cdd:pfam09311 255 TNE------------------KAAVEQLVFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQL 300
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1361-1516 |
2.89e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.45 E-value: 2.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1361 ELADALKKLSMSEASLEVITRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKE---------RE 1431
Cdd:COG1579 11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEeqlgnvrnnKE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1432 VMAVSQKVQEYSSAAAGDENAIKELEGHVQKLEIENAKFEATAKQQAGQIDILQKELRETLSirhKLEELIASLQSSKMG 1511
Cdd:COG1579 91 YEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELA---ELEAELEELEAEREE 167
|
....*
gi 1774923325 1512 LEEKL 1516
Cdd:COG1579 168 LAAKI 172
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
999-1216 |
4.08e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 4.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 999 NARIAQEDILNNIRRKSEEIENEKmwTKNAEVHGQLSKIDEREKDLILQNSNLQEEMNVLKLELdhvrSQNQQEESKYMD 1078
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALK--KEEKALLKQLAALERRIAALARRIRALEQELAALEAEL----AELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1079 ENENLKEKIADLRRDLKMNEETLTQTVIQYNSQLHALKTENTMLCSKLEHEKQgkdrLETELESIRSRLTSTLQEVERNQ 1158
Cdd:COG4942 98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE----QAEELRADLAELAALRAELEAER 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1774923325 1159 ALKIEVERTLQRERDEWLRSQDKLNHELSTIRENNNNLSQQLIRAETKSNSLENELRQ 1216
Cdd:COG4942 174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
855-1377 |
4.21e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 42.37 E-value: 4.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 855 LKFQNIIHEYER---TIQREN-GRYKLLASKVKKMENEKKDLQQIAEKNRELKSMLDHQK-VESESDLNSLRFTLKQEee 929
Cdd:COG5022 791 LKWRLFIKLQPLlslLGSRKEyRSYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLIQKfGRSLKAKKRFSLLKKET-- 868
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 930 krknaemLYGKSQEQLRRKEDQCCQE-MEAKQLLELTIRNLELEMRSMQNTVRQVEEERNEVQRLLshEHNARIaqEDIL 1008
Cdd:COG5022 869 -------IYLQSAQRVELAERQLQELkIDVKSISSLKLVNLELESEIIELKKSLSSDLIENLEFKT--ELIARL--KKLL 937
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1009 NNIrrkseEIENEKmwTKNAEVHGQLSKIDEREKDLILQNSNLQEEMNVLKLELDHVRSQNQQEESKYMDENENLKEKIA 1088
Cdd:COG5022 938 NNI-----DLEEGP--SIEYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGA 1010
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1089 DLRRDLKMNEETLTQTVIQYNSQLhaLKTENTMLCSKLEHEKQgkdrletelesiRSRLTSTLQEVERnQALKIEVERTL 1168
Cdd:COG5022 1011 LQESTKQLKELPVEVAELQSASKI--ISSESTELSILKPLQKL------------KGLLLLENNQLQA-RYKALKLRREN 1075
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1169 QRERDEWLRSQDKLNHELSTI-----RENNNNLSQ-----QLIRAETKSNSLENE----LRQTNTSLQDKVILSESTQRE 1234
Cdd:COG5022 1076 SLLDDKQLYQLESTENLLKTInvkdlEVTNRNLVKpanvlQFIVAQMIKLNLLQEiskfLSQLVNTLEPVFQKLSVLQLE 1155
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1235 LTHTcGRIKELEHTLQLEK-DKICKSTVKQES-LQEKLAQIQSENMLLRQQIEDVNNkgiiKDKTVSDVQDKFTEIIAKI 1312
Cdd:COG5022 1156 LDGL-FWEANLEALPSPPPfAALSEKRLYQSAlYDEKSKLSSSEVNDLKNELIALFS----KIFSGWPRGDKLKKLISEG 1230
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1774923325 1313 R------------ADAERQVQIIEERNK-DLIIKYNETREQLYRLETEKVERESTLRQLQQELADAL-KKLSMSEASLE 1377
Cdd:COG5022 1231 WvpteystslkgfNNLNKKFDTPASMSNeKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLfNALRTKASSLR 1309
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
865-1103 |
4.59e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 42.05 E-value: 4.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 865 ERTIQRENGRYKLLASKVKKMENEKKDLQQIaEKNRELKSMLDHQKVESESDLNSLRFTLKQEEEKRKNAEMLYGKSQEQ 944
Cdd:PTZ00121 1595 EEVMKLYEEEKKMKAEEAKKAEEAKIKAEEL-KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 945 LRRKEDQCCQEMEAKQLLELTIRNLElEMRSMQNTVRQVEEERNEVQRLLSHEHNARIAQEDIlnnirRKSEEIENEKmw 1024
Cdd:PTZ00121 1674 KKKAEEAKKAEEDEKKAAEALKKEAE-EAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEA-----KKEAEEDKKK-- 1745
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1774923325 1025 tknaevhGQLSKIDEREKDLILQnsnLQEEMNVLKLELDHVRSQNQQEESKymDENENLKEKIADLRRDLKMNEETLTQ 1103
Cdd:PTZ00121 1746 -------AEEAKKDEEEKKKIAH---LKKEEEKKAEEIRKEKEAVIEEELD--EEDEKRRMEVDKKIKDIFDNFANIIE 1812
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
909-1159 |
4.76e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 4.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 909 QKVESESDLNSLRFTLKQEEEKRKNAEMLYGKSQEQLRRKEDQccqemeaKQLLELTIRNLELEMRSMQNTVRQVEEERN 988
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR-------IAALARRIRALEQELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 989 EVQRLLShehnariAQEDILNNIRRKseeienekmwtknAEVHGQLSKIderekDLILQNSNLQEEMNVLKLeLDHVRSQ 1068
Cdd:COG4942 94 ELRAELE-------AQKEELAELLRA-------------LYRLGRQPPL-----ALLLSPEDFLDAVRRLQY-LKYLAPA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1069 NQQEESKYMDENENLKEKIADLRRDLKMNEETLTQTVIQYNsQLHALKTENTMLCSKLEHEKQGKDRLETELESIRSRLT 1148
Cdd:COG4942 148 RREQAEELRADLAELAALRAELEAERAELEALLAELEEERA-ALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226
|
250
....*....|.
gi 1774923325 1149 STLQEVERNQA 1159
Cdd:COG4942 227 ALIARLEAEAA 237
|
|
| PHA02736 |
PHA02736 |
Viral ankyrin protein; Provisional |
65-191 |
4.79e-03 |
|
Viral ankyrin protein; Provisional
Pssm-ID: 165103 [Multi-domain] Cd Length: 154 Bit Score: 39.86 E-value: 4.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 65 DKENRTPLHIACANGQldtVKVLLEHKSKLNlcdNDNRSPLLK----AIQC-----------QQESCaTVLLEHNADPNL 129
Cdd:PHA02736 14 DIEGENILHYLCRNGG---VTDLLAFKNAIS---DENRYLVLEynrhGKQCvhivsnpdkadPQEKL-KLLMEWGADING 86
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1774923325 130 VD-INGNAALHLAALIPSVSIAKQLLEH-GANINAFNKEGCTPLILAVTENNEEMVEFLLKEGA 191
Cdd:PHA02736 87 KErVFGNTPLHIAVYTQNYELATWLCNQpGVNMEILNYAFKTPYYVACERHDAKMMNILRAKGA 150
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
1155-1595 |
4.86e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 42.25 E-value: 4.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1155 ERNQALK--IEVERTLQRERDEWLRSQDKLNH---ELSTIRENNNNLSQQLIRAETKSNSLENELRQTNTSLQDKVILSE 1229
Cdd:PRK04863 280 ERRVHLEeaLELRRELYTSRRQLAAEQYRLVEmarELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKIERYQADLEE 359
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1230 STQRelthtcgrikeLEHTLQLEKDkickSTVKQESLQEKLAQIQSENMLLRQQIEDVnnkgiikdKTVSDVQDKfteii 1309
Cdd:PRK04863 360 LEER-----------LEEQNEVVEE----ADEQQEENEARAEAAEEEVDELKSQLADY--------QQALDVQQT----- 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1310 akiRADAERQVQIIEERNKDLIikynetreQLYRLETEKVE-RESTLRQLQQELADAL----KKLSMSEA-------SLE 1377
Cdd:PRK04863 412 ---RAIQYQQAVQALERAKQLC--------GLPDLTADNAEdWLEEFQAKEQEATEELlsleQKLSVAQAahsqfeqAYQ 480
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1378 VITRYRNDIEGEKQilqkeVEKFRIKVQDLEEQCNQAERLHhQLKNLLEDKEREVM---AVSQKVQEYSSAAAGDENAIK 1454
Cdd:PRK04863 481 LVRKIAGEVSRSEA-----WDVARELLRRLREQRHLAEQLQ-QLRMRLSELEQRLRqqqRAERLLAEFCKRLGKNLDDED 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1455 ELEGHVQKLEIENAKFEATAKQQAgqidilqkELRETLsiRHKLEELIASLQSskmgLEEKLNHQVHKQTALSQSAQDSH 1534
Cdd:PRK04863 555 ELEQLQEELEARLESLSESVSEAR--------ERRMAL--RQQLEQLQARIQR----LAARAPAWLAAQDALARLREQSG 620
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1774923325 1535 nlweEELKSRSRL-GIRLAELEHEKA--EFADQVESEKKKVKKLIEHKRSMEARFDQEIKRNAE 1595
Cdd:PRK04863 621 ----EEFEDSQDVtEYMQQLLEREREltVERDELAARKQALDEEIERLSQPGGSEDPRLNALAE 680
|
|
| PHA02884 |
PHA02884 |
ankyrin repeat protein; Provisional |
150-223 |
4.92e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165212 [Multi-domain] Cd Length: 300 Bit Score: 41.12 E-value: 4.92e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1774923325 150 AKQLLEHGANINAFNKEG-CTPLILAVTENNEEMVEFLLKEGADINACDRGGRTSLMISSNNGQNNLVRILLQNE 223
Cdd:PHA02884 86 AKLLIRYGADVNRYAEEAkITPLYISVLHGCLKCLEILLSYGADINIQTNDMVTPIELALMICNNFLAFMICDNE 160
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
946-1270 |
5.12e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 41.81 E-value: 5.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 946 RRKEDQCCQEMEAKQLLELTIRNLELEMRSMQNTVRQVEEERNEVQRLLSHEHNARIAQEDILNNIRrKSEEIENE---K 1022
Cdd:PLN02939 40 RGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHNRASMQRDE-AIAAIDNEqqtN 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1023 MWTKNAEVHGQLSK----IDEREKDLILQNS-----------------NLQEEMNVLKLELDH--VRSQNQQEESKYMDE 1079
Cdd:PLN02939 119 SKDGEQLSDFQLEDlvgmIQNAEKNILLLNQarlqaledlekiltekeALQGKINILEMRLSEtdARIKLAAQEKIHVEI 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1080 NENLKEKiadLRRDLKMNEETLTQTVIQYNSQLHALKTENT-------MLCSKLEHEKQGKDRLETeLESIRSRLTSTLQ 1152
Cdd:PLN02939 199 LEEQLEK---LRNELLIRGATEGLCVHSLSKELDVLKEENMllkddiqFLKAELIEVAETEERVFK-LEKERSLLDASLR 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1153 EVE-RNQALKIEVERTLQRERDEWLRSQDKLNHELSTIR---ENNNNLSQQLIRAETKSNSLENELRQTNTS-------- 1220
Cdd:PLN02939 275 ELEsKFIVAQEDVSKLSPLQYDCWWEKVENLQDLLDRATnqvEKAALVLDQNQDLRDKVDKLEASLKEANVSkfssykve 354
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1774923325 1221 -LQDKV-ILSESTQRELTHTCGRIKELEHTLQLEKDKIckSTVKQESLQEKL 1270
Cdd:PLN02939 355 lLQQKLkLLEERLQASDHEIHSYIQLYQESIKEFQDTL--SKLKEESKKRSL 404
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
1375-1526 |
5.34e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 41.74 E-value: 5.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1375 SLEVITRYRNDIEGEKqilqkevEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEYSSAaagDENAIK 1454
Cdd:PRK00409 500 PENIIEEAKKLIGEDK-------EKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEE---EDKLLE 569
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1774923325 1455 ELEGHVQKLeIENAKFEATAKQQagqiDILQKELRETLSI-RHKLEELIASLQSSKMGLEEKLNHQVHKQTAL 1526
Cdd:PRK00409 570 EAEKEAQQA-IKEAKKEADEIIK----ELRQLQKGGYASVkAHELIEARKRLNKANEKKEKKKKKQKEKQEEL 637
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
892-1224 |
5.85e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 41.82 E-value: 5.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 892 LQQIAEKNRELKSMLDHQKVESESDLNSLrftlkqeeekrkNAEMLYGKSQEQLRRKE----DQCcQEMEAKQ--LLELT 965
Cdd:PRK11281 169 SQRLQQIRNLLKGGKVGGKALRPSQRVLL------------QAEQALLNAQNDLQRKSlegnTQL-QDLLQKQrdYLTAR 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 966 IRNLELEMRSMQNTV--RQVEEERNEVQRLLSHEHNARI------AQEDILNniRRKSEEI--ENEKMWT---KNAEVHG 1032
Cdd:PRK11281 236 IQRLEHQLQLLQEAInsKRLTLSEKTVQEAQSQDEAARIqanplvAQELEIN--LQLSQRLlkATEKLNTltqQNLRVKN 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1033 QLskiderekDLILQ-NSNLQEEMNVLKLELDHVRSQNQQEES-KYMDENENLKEKIADLRrdlkmneetLTQtvIQYNS 1110
Cdd:PRK11281 314 WL--------DRLTQsERNIKEQISVLKGSLLLSRILYQQQQAlPSADLIEGLADRIADLR---------LEQ--FEINQ 374
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1111 QLHALKTENTMLcsklehekqgkDRLEtelesirSRLTSTLQEVERNQALKIevertlQRERDEWLrsqDKLNHELstir 1190
Cdd:PRK11281 375 QRDALFQPDAYI-----------DKLE-------AGHKSEVTDEVRDALLQL------LDERRELL---DQLNKQL---- 423
|
330 340 350
....*....|....*....|....*....|....*..
gi 1774923325 1191 enNNNLSQqliraetkSNSLEN---ELRQTNTSLQDK 1224
Cdd:PRK11281 424 --NNQLNL--------AINLQLnqqQLLSVSDSLQST 450
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
133-162 |
5.95e-03 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 36.03 E-value: 5.95e-03
10 20 30
....*....|....*....|....*....|
gi 1774923325 133 NGNAALHLAALIPSVSIAKQLLEHGANINA 162
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
1363-1505 |
6.16e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.38 E-value: 6.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1363 ADALKKLSMSEASLEVITRYRNDIEGE----KQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKEREVMAVSQK 1438
Cdd:COG2433 370 ARVIRGLSIEEALEELIEKELPEEEPEaereKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERE 449
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1774923325 1439 VQEYSSAaagdENAIKELEGHVQKLEIEnakfeatakqqagqIDILQKELRETLSIRHKLEELIASL 1505
Cdd:COG2433 450 LSEARSE----ERREIRKDREISRLDRE--------------IERLERELEEERERIEELKRKLERL 498
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
200-253 |
7.34e-03 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 36.48 E-value: 7.34e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1774923325 200 GRTSLMISSNNGQNNLVRILLQNEADINIKDEKSWTADDYGVMNGHHACSHLII 253
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1409-1599 |
7.73e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.90 E-value: 7.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1409 EQCNQAERLHHQLKNLLEDKEREVMAVSQKVQEYSSAAAGDENAIKELEGHVQKLEIENAKFEATAKQQAGQIDILQKEL 1488
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1489 REtlsIRHKLEELIASLQssKMGLEEKL---------NHQVHKQTALSQSAQDSHNLWEEELKSRSRLGIRLAELEHEKA 1559
Cdd:COG4942 100 EA---QKEELAELLRALY--RLGRQPPLalllspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1774923325 1560 EFA---DQVESEKKKVKKLIEHKRSMEARFDQEIK----RNAELQRD 1599
Cdd:COG4942 175 ELEallAELEEERAALEALKAERQKLLARLEKELAelaaELAELQQE 221
|
|
| CCCAP |
pfam15964 |
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ... |
1122-1439 |
7.79e-03 |
|
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.
Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 41.04 E-value: 7.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1122 LCSKLEHEKQGKDRLETELESIRSRLTSTLQEVERNQA-LKIEVERtLQRERDEWLRSQDKLNHELSTIRENNNN----L 1196
Cdd:pfam15964 376 LASQQEKRAQEKEALRKEMKKEREELGATMLALSQNVAqLEAQVEK-VTREKNSLVSQLEEAQKQLASQEMDVTKvcgeM 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1197 SQQLIRAETKSNSLENELRQTNTSLQDKVILSESTQRELthtcgRIKELEHTLQLEKDKICKSTVKQESLQ--EKLAQIQ 1274
Cdd:pfam15964 455 RYQLNQTKMKKDEAEKEHREYRTKTGRQLEIKDQEIEKL-----GLELSESKQRLEQAQQDAARAREECLKltELLGESE 529
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1275 SENMLLRQQIEDVnnkgiikdktvsdvQDKFTEIIAKIRADAERQVQIIEERNKDLIIKYNETREQLYRLETEKverEST 1354
Cdd:pfam15964 530 HQLHLTRLEKESI--------------QQSFSNEAKAQALQAQQREQELTQKMQQMEAQHDKTVNEQYSLLTSQ---NTF 592
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1355 LRQLQQELADALKKLSmseaslEVITRYRNDIEG---EKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLEDKERE 1431
Cdd:pfam15964 593 IAKLKEECCTLAKKLE------EITQKSRSEVEQlsqEKEYLQDRLEKLQKRNEELEEQCVQHGRMHERMKQRLRQLDKH 666
|
....*...
gi 1774923325 1432 VMAVSQKV 1439
Cdd:pfam15964 667 CQATAQQL 674
|
|
| PHA02792 |
PHA02792 |
ankyrin-like protein; Provisional |
123-206 |
7.90e-03 |
|
ankyrin-like protein; Provisional
Pssm-ID: 165155 [Multi-domain] Cd Length: 631 Bit Score: 41.09 E-value: 7.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 123 HNADPNLVDI---NGNAA-------LHLAALIPS--------VSIAKQLLEHGANINAFNKEGCTPLILAVTENNEEMVE 184
Cdd:PHA02792 348 DNRDPKVVEYilkNGNVVvedddniINIMPLFPTlsihesdvLSILKLCKPYIDDINKIDKHGRSILYYCIESHSVSLVE 427
|
90 100
....*....|....*....|..
gi 1774923325 185 FLLKEGADINACDRGGRTSLMI 206
Cdd:PHA02792 428 WLIDNGADINITTKYGSTCIGI 449
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
109-197 |
8.07e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 41.20 E-value: 8.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 109 IQCQQESCATVLLEHNADPNLVDINGNAALHLAALIPSVSIAKQLLEHGANINAFNKEGCTPLILAVTENNEEMVEFLLK 188
Cdd:PHA02876 153 IQQDELLIAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIID 232
|
....*....
gi 1774923325 189 EGADINACD 197
Cdd:PHA02876 233 NRSNINKND 241
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
874-1021 |
8.37e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.92 E-value: 8.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 874 RYKLLASKVKKMENEKKDLQQIAEKN---------RELKSMLDHQKVESESDLNSLRFTLKQEEEKRKNAEMLYGKSQEQ 944
Cdd:PRK12704 25 RKKIAEAKIKEAEEEAKRILEEAKKEaeaikkealLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLEL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 945 LRRKEDQCCQEMEAKQLLELTIRNLELEMRSMQntvrqvEEERNEVQRL--LSHEHnariAQEDILNNIRRKSE------ 1016
Cdd:PRK12704 105 LEKREEELEKKEKELEQKQQELEKKEEELEELI------EEQLQELERIsgLTAEE----AKEILLEKVEEEARheaavl 174
|
....*..
gi 1774923325 1017 --EIENE 1021
Cdd:PRK12704 175 ikEIEEE 181
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
1293-1426 |
8.97e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.92 E-value: 8.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1293 IKDKTVSDVQDKFTEIIAKIRADAERQVQIIEERNKDLIIKYnetREQLyrlETEKVERESTLRQLQqeladalKKLSMS 1372
Cdd:PRK12704 28 IAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKL---RNEF---EKELRERRNELQKLE-------KRLLQK 94
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1774923325 1373 EASLEvitRYRNDIEGEKQILQKEVEKFRIKVQDLEEQCNQAERLHHQLKNLLE 1426
Cdd:PRK12704 95 EENLD---RKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELE 145
|
|
| KIP1 |
COG5059 |
Kinesin-like protein [Cytoskeleton]; |
972-1196 |
9.93e-03 |
|
Kinesin-like protein [Cytoskeleton];
Pssm-ID: 227392 [Multi-domain] Cd Length: 568 Bit Score: 40.88 E-value: 9.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 972 EMRSMQNTVRQVEEERN--EVQRLLSHEHNARIAQEDILNNIRRKSEEIENEKMWTKNaevhgQLSKIDEREKDLILQNS 1049
Cdd:COG5059 341 QVNSSSDSSREIEEIKFdlSEDRSEIEILVFREQSQLSQSSLSGIFAYMQSLKKETET-----LKSRIDLIMKSIISGTF 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774923325 1050 NLQEEMNV----LKLELDHVRSQNQQEESKYMDENENLKEKIADL---RRDLKMNEETLTQTVIQYNSQLHALKTENTML 1122
Cdd:COG5059 416 ERKKLLKEegwkYKSTLQFLRIEIDRLLLLREEELSKKKTKIHKLnklRHDLSSLLSSIPEETSDRVESEKASKLRSSAS 495
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1774923325 1123 CSKLEHEKQGkdrlETELESIRSRLTSTLQEVERNQALKIEVERTLQRERDEWLRSQDKLNHELSTIRENNNNL 1196
Cdd:COG5059 496 TKLNLRSSRS----HSKFRDHLNGSNSSTKELSLNQVDLAGSERKVSQSVGELLRETQSLNKSLSSLGDVIHAL 565
|
|
| |
