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Conserved domains on  [gi|218722064|gb|EED21482|]
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centrin-binding protein Sfi1, putative [Talaromyces stipitatus ATCC 10500]

Protein Classification

Sfi1 family protein( domain architecture ID 12093899)

Sfi1 family protein similar to Schizosaccharomyces pombe protein sfi1, also known as suppressor of fermentation induced loss of stress resistance protein 1, which is a component of the spindle pole body (SPB) half-bridge involved in the initial steps of SPB duplication

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Sfi1 pfam08457
Sfi1 spindle body protein; This is a family of fungal spindle pole body proteins that play a ...
 355-925 0e+00

Sfi1 spindle body protein; This is a family of fungal spindle pole body proteins that play a role in spindle body duplication. They contain binding sites for calmodulin-like proteins called centrins which are present in microtubule-organizing centres.


:

Pssm-ID: 430007 [Multi-domain]  Cd Length: 570  Bit Score: 666.69  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   355 ELEKKRQNSRTKRFFRHLENRAAKARDLYLMTKAFSHWAQLTSDELSKASAAREHILSIKYFNAWREITAVNVMKAERFA 434
Cdd:pfam08457    1 ILEEKRRAAETERFFEHLERRAARARDLYLLTKAFTHWAQAASEEVERTSAARRHILRKKYFNAWREITAVNELKAQRFA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   435 IQKPLDGWRRKIQQIRTLDDHAIHAHEYNRKRKYLMMLLWNFYyEHRAPEWSDFRLMKGAFLSWIRALRRQREREAEIDH 514
Cdd:pfam08457   81 LKRPLGAWRRRTLQIRVREEVAVQVYQENLLKRSFWKWFWEFC-ERRAPQWYDFRLKRRSLLTWLRKFRTLREREQEAEA 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   515 GLRQELLHATLKTWSYRLRSVEAAQLDADMGYRKKLLGDQMEVWRAQTRLQPAAIQIATKIDSRVLKTTLIQWRLRTESV 594
Cdd:pfam08457  160 KRKRLLLSSALQIWSERTEAVQAAEQEADSFRRRKLLRRALDEWRIQARLEPALRQVSAKVDRRILRSALSVWKLRARMS 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   595 QHAKEADRLRVLRNTWTTWNDHLRCYALKERIDERLKKEAIYRWILAERYRLAQRIRDQRIQREAFAQFIFTVRDTSKEL 674
Cdd:pfam08457  240 RQAREVDRARILRNAWTTWNDELRCKALRERIDERLKLEALYKWVLEERLRLFQRIREQRLKREVLSTWVTNTRDTRTRL 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   675 LQRENQYFRHYNEDLARSALDCWRNKLAVQRQREYAAMEFYVPRIEQEALTIWNSRHQHLQNLDKWSRDAQFYFITTKFI 754
Cdd:pfam08457  320 LRHEEEFEEHRNRKLLRSKLLKWRDQLAEQREREIAANEFYAPRLLQEALDAWRERHQHVQKLEKWARDARFYFLATRTL 399

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   755 KLWHNAALDASKKRRQEAYVKIRRKVKMNIAASALRVWYDKSRRMTNLHNQANELMQTKLLIYSTELVSRWREKTAKITQ 834
Cdd:pfam08457  400 KKWRAATEESRRERRQDAYAQVRRKVKINLARRALSKWRSKAAEVADLEQQADQLRQNRLLEDAIELFDRWRERTAKRKQ 479

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   835 DTQDAEVYYHRQLAYHQLSRWMDECEIYRGLEEQAEVLDLIRISGVVSAQLRKLSLRIFQIRSAAEMAESLHDRISRKHH 914
Cdd:pfam08457  480 RAEDADQFYAEQLLRSYLARWRERLRELRELEQDADAYRREHTLGQAAAALRKWSLRLFQIRSREETADALRERNLRKHL 559

                          570
                   ....*....|.
gi 218722064   915 RNMLRHWSAKV 925
Cdd:pfam08457  560 RNMLRHWLQKA 570
 
Name Accession Description Interval E-value
Sfi1 pfam08457
Sfi1 spindle body protein; This is a family of fungal spindle pole body proteins that play a ...
 355-925 0e+00

Sfi1 spindle body protein; This is a family of fungal spindle pole body proteins that play a role in spindle body duplication. They contain binding sites for calmodulin-like proteins called centrins which are present in microtubule-organizing centres.


Pssm-ID: 430007 [Multi-domain]  Cd Length: 570  Bit Score: 666.69  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   355 ELEKKRQNSRTKRFFRHLENRAAKARDLYLMTKAFSHWAQLTSDELSKASAAREHILSIKYFNAWREITAVNVMKAERFA 434
Cdd:pfam08457    1 ILEEKRRAAETERFFEHLERRAARARDLYLLTKAFTHWAQAASEEVERTSAARRHILRKKYFNAWREITAVNELKAQRFA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   435 IQKPLDGWRRKIQQIRTLDDHAIHAHEYNRKRKYLMMLLWNFYyEHRAPEWSDFRLMKGAFLSWIRALRRQREREAEIDH 514
Cdd:pfam08457   81 LKRPLGAWRRRTLQIRVREEVAVQVYQENLLKRSFWKWFWEFC-ERRAPQWYDFRLKRRSLLTWLRKFRTLREREQEAEA 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   515 GLRQELLHATLKTWSYRLRSVEAAQLDADMGYRKKLLGDQMEVWRAQTRLQPAAIQIATKIDSRVLKTTLIQWRLRTESV 594
Cdd:pfam08457  160 KRKRLLLSSALQIWSERTEAVQAAEQEADSFRRRKLLRRALDEWRIQARLEPALRQVSAKVDRRILRSALSVWKLRARMS 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   595 QHAKEADRLRVLRNTWTTWNDHLRCYALKERIDERLKKEAIYRWILAERYRLAQRIRDQRIQREAFAQFIFTVRDTSKEL 674
Cdd:pfam08457  240 RQAREVDRARILRNAWTTWNDELRCKALRERIDERLKLEALYKWVLEERLRLFQRIREQRLKREVLSTWVTNTRDTRTRL 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   675 LQRENQYFRHYNEDLARSALDCWRNKLAVQRQREYAAMEFYVPRIEQEALTIWNSRHQHLQNLDKWSRDAQFYFITTKFI 754
Cdd:pfam08457  320 LRHEEEFEEHRNRKLLRSKLLKWRDQLAEQREREIAANEFYAPRLLQEALDAWRERHQHVQKLEKWARDARFYFLATRTL 399

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   755 KLWHNAALDASKKRRQEAYVKIRRKVKMNIAASALRVWYDKSRRMTNLHNQANELMQTKLLIYSTELVSRWREKTAKITQ 834
Cdd:pfam08457  400 KKWRAATEESRRERRQDAYAQVRRKVKINLARRALSKWRSKAAEVADLEQQADQLRQNRLLEDAIELFDRWRERTAKRKQ 479

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   835 DTQDAEVYYHRQLAYHQLSRWMDECEIYRGLEEQAEVLDLIRISGVVSAQLRKLSLRIFQIRSAAEMAESLHDRISRKHH 914
Cdd:pfam08457  480 RAEDADQFYAEQLLRSYLARWRERLRELRELEQDADAYRREHTLGQAAAALRKWSLRLFQIRSREETADALRERNLRKHL 559

                          570
                   ....*....|.
gi 218722064   915 RNMLRHWSAKV 925
Cdd:pfam08457  560 RNMLRHWLQKA 570
 
Name Accession Description Interval E-value
Sfi1 pfam08457
Sfi1 spindle body protein; This is a family of fungal spindle pole body proteins that play a ...
 355-925 0e+00

Sfi1 spindle body protein; This is a family of fungal spindle pole body proteins that play a role in spindle body duplication. They contain binding sites for calmodulin-like proteins called centrins which are present in microtubule-organizing centres.


Pssm-ID: 430007 [Multi-domain]  Cd Length: 570  Bit Score: 666.69  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   355 ELEKKRQNSRTKRFFRHLENRAAKARDLYLMTKAFSHWAQLTSDELSKASAAREHILSIKYFNAWREITAVNVMKAERFA 434
Cdd:pfam08457    1 ILEEKRRAAETERFFEHLERRAARARDLYLLTKAFTHWAQAASEEVERTSAARRHILRKKYFNAWREITAVNELKAQRFA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   435 IQKPLDGWRRKIQQIRTLDDHAIHAHEYNRKRKYLMMLLWNFYyEHRAPEWSDFRLMKGAFLSWIRALRRQREREAEIDH 514
Cdd:pfam08457   81 LKRPLGAWRRRTLQIRVREEVAVQVYQENLLKRSFWKWFWEFC-ERRAPQWYDFRLKRRSLLTWLRKFRTLREREQEAEA 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   515 GLRQELLHATLKTWSYRLRSVEAAQLDADMGYRKKLLGDQMEVWRAQTRLQPAAIQIATKIDSRVLKTTLIQWRLRTESV 594
Cdd:pfam08457  160 KRKRLLLSSALQIWSERTEAVQAAEQEADSFRRRKLLRRALDEWRIQARLEPALRQVSAKVDRRILRSALSVWKLRARMS 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   595 QHAKEADRLRVLRNTWTTWNDHLRCYALKERIDERLKKEAIYRWILAERYRLAQRIRDQRIQREAFAQFIFTVRDTSKEL 674
Cdd:pfam08457  240 RQAREVDRARILRNAWTTWNDELRCKALRERIDERLKLEALYKWVLEERLRLFQRIREQRLKREVLSTWVTNTRDTRTRL 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   675 LQRENQYFRHYNEDLARSALDCWRNKLAVQRQREYAAMEFYVPRIEQEALTIWNSRHQHLQNLDKWSRDAQFYFITTKFI 754
Cdd:pfam08457  320 LRHEEEFEEHRNRKLLRSKLLKWRDQLAEQREREIAANEFYAPRLLQEALDAWRERHQHVQKLEKWARDARFYFLATRTL 399

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   755 KLWHNAALDASKKRRQEAYVKIRRKVKMNIAASALRVWYDKSRRMTNLHNQANELMQTKLLIYSTELVSRWREKTAKITQ 834
Cdd:pfam08457  400 KKWRAATEESRRERRQDAYAQVRRKVKINLARRALSKWRSKAAEVADLEQQADQLRQNRLLEDAIELFDRWRERTAKRKQ 479

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   835 DTQDAEVYYHRQLAYHQLSRWMDECEIYRGLEEQAEVLDLIRISGVVSAQLRKLSLRIFQIRSAAEMAESLHDRISRKHH 914
Cdd:pfam08457  480 RAEDADQFYAEQLLRSYLARWRERLRELRELEQDADAYRREHTLGQAAAALRKWSLRLFQIRSREETADALRERNLRKHL 559

                          570
                   ....*....|.
gi 218722064   915 RNMLRHWSAKV 925
Cdd:pfam08457  560 RNMLRHWLQKA 570
Sfi1 pfam08457
Sfi1 spindle body protein; This is a family of fungal spindle pole body proteins that play a ...
 296-461 1.70e-04

Sfi1 spindle body protein; This is a family of fungal spindle pole body proteins that play a role in spindle body duplication. They contain binding sites for calmodulin-like proteins called centrins which are present in microtubule-organizing centres.


Pssm-ID: 430007 [Multi-domain]  Cd Length: 570  Bit Score: 45.36  E-value: 1.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   296 LRDASSFSTYRRRATARNILIHWLTQAVRSQQRnrdmEAVAVNQDRATLLRQALDLWR------AELEKKRQNSR----T 365
Cdd:pfam08457  320 LRHEEEFEEHRNRKLLRSKLLKWRDQLAEQRER----EIAANEFYAPRLLQEALDAWRerhqhvQKLEKWARDARfyflA 395

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218722064   366 KRFFRHLENRAAKAR---------------DLYLMTKAFSHWAQLTSDELSKASAA------REHILSIKYFNAWREITA 424
Cdd:pfam08457  396 TRTLKKWRAATEESRrerrqdayaqvrrkvKINLARRALSKWRSKAAEVADLEQQAdqlrqnRLLEDAIELFDRWRERTA 475

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 218722064   425 VNVMK---AERFAIQKPLDG----WRRKIQQIRTLDDHAIHAHE 461
Cdd:pfam08457  476 KRKQRaedADQFYAEQLLRSylarWRERLRELRELEQDADAYRR 519
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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