|
Name |
Accession |
Description |
Interval |
E-value |
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
62-806 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 569.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 62 IEKIQAFEKFFTRHIdlYdKDEI-------ERKGSILVDFKELTKADeitnliPDIENALRDAPEKTLACMGLAIHQVLT 134
Cdd:COG1241 3 SDLVDKFEEFLRRYK--Y-RDEIlelaqeyPEKRSLVVDYNDLYSFD------PDLADDLLENPDEVLEAAEEALREIDL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 135 KDLErhaaelqaqeglsnggetmVNVPHIYARVYNYEPLTHLKNIRATCYGKYISIRGTVVRVSNIKPLCTNMAFQCAAC 214
Cdd:COG1241 74 EPYD-------------------VSLGDAHVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRC 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 215 GEIQSFPLPDGKYTLPTKCPVpaC-RGRSFAPLRSSplTVTLDWQLIKIQELMSDAqrEAGRIPRTIECELVHDLVDSCV 293
Cdd:COG1241 135 GTETYVPQTGEKLQEPHECPG--CgRQGPFKLLPEK--SEFIDAQKIRIQEPPEDL--PGGQQPQSIDVILEDDLVGEVR 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 294 PGDTVTVTGIVKvsnSEEGSRNKNDKCMFLLYIEANSVSnskgPKAQTAEDgckhgtlMEFSLKDLYAIREIQAEENLLK 373
Cdd:COG1241 209 PGDRVTVTGILR---IEQRTSGRGKSTIFDLYLEANSIE----VEEKEFEE-------IEITEEDEEKIKELSKDPDIYE 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 374 LVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIpiRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTS 453
Cdd:COG1241 275 KIIASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSRI--RGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTA 352
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 454 SGLTVTLSKDS-SSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANP 531
Cdd:COG1241 353 AGLTAAAVRDDfGTGRWTLEAGALVLADGGLACIDELDKMREEDRsALHEAMEQQTISIAKAGIVATLNARCSVLAAANP 432
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 532 VGGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHviairagkqkavssatvtrvlsqdsntsVLEVVS 611
Cdd:COG1241 433 KYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARH----------------------------ILKVHR 484
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 612 EKPLSERLKVAPGEQTDP-IPHQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQSQRVGSS-PITTRQLESLIRLT 689
Cdd:COG1241 485 AGELLEQEIEEETEEVKPeIDPDLLRKYIAYARRNVFPVLTEEAKDLIEDFYVDMRKKGEDEDSPvPITARQLEALIRLA 564
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 690 EARARLELREEATREDAEDIIEIMKHSMLGTYSD-EFGNLDFERSQHGSGMSNRSTAKRFISALNSIAERtYNNIFQYHQ 768
Cdd:COG1241 565 EASARMRLSDTVTEEDAERAIRLVDSCLKDVGVDpETGKFDIDVIETGTSKSQRDKMKLIKDIIKELEEE-SSGGAPIED 643
|
730 740 750
....*....|....*....|....*....|....*...
gi 148696414 769 LRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKIYQL 806
Cdd:COG1241 644 VIEEAEEEGIDREKAEELIEKLKRKGEIYEPKPGHYKK 681
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
374-716 |
0e+00 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 542.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 374 LVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTS 453
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 454 SGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVG 533
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGSQHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPVG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 534 GHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHviairagkqkavssatvtrvlsqdsntsvlevvsek 613
Cdd:cd17759 161 GHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEH------------------------------------ 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 614 plserlkvapgeqtdpipHQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQSQRVGSSPITTRQLESLIRLTEARA 693
Cdd:cd17759 205 ------------------HQLLRKYISYARQYVNPVLSKDASEALQEFYLELRKQNQLADSSPITTRQLESLIRLTEARA 266
|
330 340
....*....|....*....|...
gi 148696414 694 RLELREEATREDAEDIIEIMKHS 716
Cdd:cd17759 267 RLELREEATKEDAEDVIEIMKES 289
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
374-716 |
2.81e-157 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 460.27 E-value: 2.81e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 374 LVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDknRIPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTS 453
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILED--GTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 454 SGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPV 532
Cdd:cd17706 79 AGLTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRtALHEAMEQQTISIAKAGIVTTLNARCSILAAANPK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 533 GGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIRAGKQKAVssatvtrvlsqdsntsvlevvse 612
Cdd:cd17706 159 GGRYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDPEE----------------------- 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 613 kplserlKVAPGEQTDPIPHQLLRKYIGYARQyVHPRLSTDAAQALQDFYLELRKQSQRVGSSPITTRQLESLIRLTEAR 692
Cdd:cd17706 216 -------QVKPEEDGIPIDIELLRKYILYARQ-IHPKISEEAREKLVRWYVELRKESERRSTIPITARQLESVIRLAEAH 287
|
330 340
....*....|....*....|....
gi 148696414 693 ARLELREEATREDAEDIIEIMKHS 716
Cdd:cd17706 288 AKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM |
smart00350 |
minichromosome maintenance proteins; |
176-718 |
4.76e-157 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 467.12 E-value: 4.76e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 176 LKNIRATCYGKYISIRGTVVRVSNIKPLCTNMAFQCAACGEIQSFPLPDGKYTLPTKCPVPACRGRSFAPLRSSpLTVTL 255
Cdd:smart00350 5 IRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTPFSLNHE-RSTFI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 256 DWQLIKIQELMSDAQreAGRIPRTIECELVHDLVDSCVPGDTVTVTGIVKVSNSEEGSRNKNDKCMFLLYIEANSVsnsK 335
Cdd:smart00350 84 DFQKIKLQESPEEVP--VGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPYGFKLNTVKGLPVFATYIEANHV---R 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 336 GPKAQTAEDGCkHGTLMEFSLKDLYAIREIQAEENLLKLVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIpiRG 415
Cdd:smart00350 159 KLDYKRSFEDS-SFSVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKI--RG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 416 DPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTSSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQ 495
Cdd:smart00350 236 DINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDS 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 496 HQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLL 574
Cdd:smart00350 316 DRtAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDREL 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 575 SEHVIAIragkqkavssatvtRVLSQDSNTSVLEVvsekplserlkvapgeqtdPIPHQLLRKYIGYARQYVHPRLSTDA 654
Cdd:smart00350 396 AKHVVDL--------------HRYSHPEEDEAFEP-------------------PLSQEKLRKYIAYAREKIKPKLSEEA 442
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 148696414 655 AQALQDFYLELRK---QSQRVGSSPITTRQLESLIRLTEARARLELREEATREDAEDIIEIMKHSML 718
Cdd:smart00350 443 ADKLVKAYVDLRKedsQTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
374-713 |
2.80e-115 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 352.14 E-value: 2.80e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 374 LVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIpiRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTS 453
Cdd:cd17761 2 KIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRI--RGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 454 SGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPV 532
Cdd:cd17761 80 AGLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRsALHEAMEQQTISIAKAGIVATLNARAAVLAAANPK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 533 GGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIRAGKQkavssatvtrvlsqdsntsvlevvse 612
Cdd:cd17761 160 FGRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGE-------------------------- 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 613 kplserlkvaPGEQTDPIPHQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQSQRVGSS-PITTRQLESLIRLTEA 691
Cdd:cd17761 214 ----------MREIKPEIDPDLLRKYIAYARKNVRPVLTEEAKQLIKDFYVEMRKSGQETPSPvPITARQLEALVRLSEA 283
|
330 340
....*....|....*....|..
gi 148696414 692 RARLELREEATREDAEDIIEIM 713
Cdd:cd17761 284 SARMRLSQEVTLEDAERAIRIM 305
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
358-582 |
2.88e-114 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 346.05 E-value: 2.88e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 358 DLYAIREIQAEENLLKLVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIpiRGDPHVLIVGDPGLGKSQMLQAAC 437
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRL--RGDINVLLVGDPGTAKSQLLKYVE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 438 NVAPRGVYVCGNTTTSSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQ-HQALLEAMEQQSISLAKAGVV 516
Cdd:pfam00493 79 KIAPRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEdRVALHEAMEQQTISIAKAGIV 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 148696414 517 CSLPARTSIIAAANPVGGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIR 582
Cdd:pfam00493 159 ATLNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
375-716 |
5.57e-107 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 330.95 E-value: 5.57e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 375 VVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIpiRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTSS 454
Cdd:cd17753 2 IINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRI--RGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 455 GLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVG 533
Cdd:cd17753 80 GLTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRtSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 534 GHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIRAGKQKavssatvtrvlSQDSNTSVLEVVSEK 613
Cdd:cd17753 160 GRYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHP-----------ENDEDREGEEEKNQR 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 614 PLSERLKVapgeqtDPIPHQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQSQRVGSSPITTRQLESLIRLTEARA 693
Cdd:cd17753 229 QRPKETKV------EPIPQELLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRKESMATGSLPITVRHLESIIRISEAHA 302
|
330 340
....*....|....*....|...
gi 148696414 694 RLELREEATREDAEDIIEIMKHS 716
Cdd:cd17753 303 KMHLREYVSEEDVDMAIRVMLDS 325
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
376-716 |
2.14e-102 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 318.54 E-value: 2.14e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 376 VNSLCPVIFGHELVKAGLTLALFGGSQKYADDKnrIPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTSSG 455
Cdd:cd17757 3 VRSIAPSIYGHEEVKKGILLMLLGGVHKITREG--ISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 456 LTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGG 534
Cdd:cd17757 81 LTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQvAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 535 HYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIRAGKQKAVSSatvtrvlsqdsntsvlevvsekp 614
Cdd:cd17757 161 RYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKREEAIEP----------------------- 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 615 lserlkvapgeqtdPIPHQLLRKYIGYARQyVHPRLSTDAAQALQDFYLELRKQSQRVGSSP---ITTRQLESLIRLTEA 691
Cdd:cd17757 218 --------------PFTAEQLKRYIAYART-FKPKLTKEAKDELVEQYKELRQDDASGSTRSsyrITVRQLESLIRLSEA 282
|
330 340
....*....|....*....|....*
gi 148696414 692 RARLELREEATREDAEDIIEIMKHS 716
Cdd:cd17757 283 IARLHCSDEVTPEHVEEAARLLKKS 307
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
374-714 |
4.84e-101 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 315.14 E-value: 4.84e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 374 LVVNSLCPVIFGHELVKAGLTLALFGGSQKyADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTS 453
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRK-DFTKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 454 SGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALL-EAMEQQSISLAKAGVVCSLPARTSIIAAANPV 532
Cdd:cd17755 80 VGLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLhEVMEQQTLSIAKAGIITTLNARTSILASANPI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 533 GGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIragkqkavssatvtrvlsqdsntsvleVVSE 612
Cdd:cd17755 160 GSRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSL---------------------------YLED 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 613 KPLSerlkvapgEQTDPIPHQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQ-SQRVGSSPITTRQLESLIRLTEA 691
Cdd:cd17755 213 TPEH--------IQDEVLDVEVLTDYISYAREHIHPKLSEEAAQELVQAYVDMRKMgSDARKRITATPRQLESLIRLAEA 284
|
330 340
....*....|....*....|...
gi 148696414 692 RARLELREEATREDAEDIIEIMK 714
Cdd:cd17755 285 HAKMRLSNVVEAEDVEEAVRLIR 307
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
374-716 |
1.06e-99 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 311.62 E-value: 1.06e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 374 LVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIpiRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTS 453
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRL--RGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 454 SGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMgNQHQ--ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANP 531
Cdd:cd17756 79 AGLTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKM-REDDrvAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 532 VGGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIRAGKQKAVSSatvtrvlsqdsntsvlevvs 611
Cdd:cd17756 158 VFGRYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQS-------------------- 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 612 ekplserlkvapGEQTDPIPHQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQ-------SQRVGSSPITTRQLES 684
Cdd:cd17756 218 ------------QENEGEIPISKLKRYIAYCRAKCAPRLSEEAAEKLSNHYVTIRKDvrqneleSDNRSSIPITVRQLEA 285
|
330 340 350
....*....|....*....|....*....|..
gi 148696414 685 LIRLTEARARLELREEATREDAEDIIEIMKHS 716
Cdd:cd17756 286 IIRISESLAKMELSPIATEKHVEEAIRLFQVS 317
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
378-716 |
2.53e-92 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 292.01 E-value: 2.53e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 378 SLCPVIFGHELVKAGLTLALFGGSQKYADDknrIPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTSSGLT 457
Cdd:cd17758 5 SIAPEIYGHEDVKKALLLLLVGGVDKRGDG---MKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGLT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 458 VTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHY 536
Cdd:cd17758 82 AAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRtAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGRY 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 537 NKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHviairagkqkavssatVTRVLSQDsntsvlevvsekpls 616
Cdd:cd17758 162 NPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEH----------------VTYVHQHN--------------- 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 617 erlkVAPGEQTDPIPHQLLRKYIGYARQYvHPRLSTDAAQALQDFYLELRKQSQRVGSSPITT-RQLESLIRLTEARARL 695
Cdd:cd17758 211 ----KQPDSDFEPLDPKLLRAYIALAKRK-RPTVPPALADYIVQAYVEMRQEAKRSKDFTFTTpRTLLAILRLSQALARL 285
|
330 340
....*....|....*....|.
gi 148696414 696 ELREEATREDAEDIIEIMKHS 716
Cdd:cd17758 286 RLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
374-716 |
2.74e-87 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 278.66 E-value: 2.74e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 374 LVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIpiRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTS 453
Cdd:cd17760 1 EILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRV--RGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 454 SGLTVTLSKDssSGDFALEAGALVLGDQGICGIDEFDKMG-NQHQALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPv 532
Cdd:cd17760 79 AGLTVTAVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKeHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 533 GGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEhviairagkqkavssatvtRVLSQDSNTSVLEVVse 612
Cdd:cd17760 156 KGQYDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISS-------------------FILENKGEPSKSSKL-- 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 613 kplserlkvapgeqtdpIPHQLLRKYIGYARQyVHPRLSTDAAQALQDFYlELRKQSQRVGSSPITTRQLESLIRLTEAR 692
Cdd:cd17760 215 -----------------WSMEKMRTYFCLIKN-LRPVLSDEANAILLRYY-QLQRQSDCRNAARTTIRMLESLIRLAEAH 275
|
330 340
....*....|....*....|....
gi 148696414 693 ARLELREEATREDAEDIIEIMKHS 716
Cdd:cd17760 276 ARLMFRETVTEEDAITVVSVMESS 299
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
165-736 |
4.89e-81 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 279.19 E-value: 4.89e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 165 ARVYNYEPLTHLKNIRATCYGKYISIRGTVVRVSNIKPLCTNMAFQCAA-----------CGEIQSFPLPDGKYTLPTKC 233
Cdd:PTZ00111 207 ARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGqkkiglndyqpCTCEHYEYVIQGEVNEPLLC 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 234 PvpACRGRSFAPLRSSpLTVTLDWQLIKIQELMS--------------DAQREAGRI----PRTIECELVHDLVDSCVPG 295
Cdd:PTZ00111 287 N--ECNSKYTFELNHN-MCVYSTKKIVKLLQSNSslnnpdkdgldnsvDNSGLNGEIymkdNEVINLNLYDDLIDSVKTG 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 296 DTVTVTGIVKVSNSEEGSRNKNDKCMFLLYIEANSVSNSKGPKAQTAEDGCKH-GTLMEFSLKDLYAIREIQAEENLLKL 374
Cdd:PTZ00111 364 DRVTVVGILKVTPIRTSTTRRTLKSLYTYFVNVIHVKVINSTNANQPEKGLKYlGNENDFSDLQVYKILELSRNPMIYRI 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 375 VVNSLCPVIFGHELVKAGLTLALFGGSqKYADDKNRIP--------IRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYV 446
Cdd:PTZ00111 444 LLDSFAPSIKARNNVKIGLLCQLFSGN-KNSSDFNKSPdacykvdnFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYT 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 447 CGNTTTSSGLTVTLS-KDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALL-EAMEQQSISLAKAGVVCSLPARTS 524
Cdd:PTZ00111 523 SGKSSSSVGLTASIKfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLyEVMEQQTVTIAKAGIVATLKAETA 602
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 525 IIAAANPVGGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEhVIA--IRAGKQKAVSSATVTrvlSQDS 602
Cdd:PTZ00111 603 ILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISL-SIAkdFLLPHMTGSGNDEDT---YDRS 678
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 603 NTSVLEvvsekplSERLKvaPGEQTDPIPHQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQS------------- 669
Cdd:PTZ00111 679 NTMHVE-------DESLR--SEKDYNKNDLDMLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQGNfqtsnldelehaq 749
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 148696414 670 ---------QRVGSSPIT--TRQLESLIRLTEARARLELREEATREDAEDIIEIMKHSMLGTYSDEF-GNLDFERSQHG 736
Cdd:PTZ00111 750 edddddlyyQSSGTRMIYvsSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQSLVDPTtGKIDFDQLHQG 828
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
374-714 |
3.99e-79 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 257.01 E-value: 3.99e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 374 LVVNSLCPVIFGHELVKAGLTLALFGGSQKyaDDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTS 453
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEK--NLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 454 SGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPV 532
Cdd:cd17754 79 VGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRvAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 533 GGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIRagkqkavssatvtRVLsqdsntsvlevvse 612
Cdd:cd17754 159 YGRYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMH-------------RYI-------------- 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 613 kplserlkvapgeqtdpiphQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQ----SQRVGSSPITTRQLESLIRL 688
Cdd:cd17754 212 --------------------KFLRKYIHYAKERIKPKLTQEAAEYIAEEYADLRNDdntkTDKARTSPITARTLETLIRL 271
|
330 340
....*....|....*....|....*.
gi 148696414 689 TEARARLELREEATREDAEDIIEIMK 714
Cdd:cd17754 272 ATAHAKARLSKTVDKVDAEVALNLLR 297
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
633-717 |
1.64e-35 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 129.20 E-value: 1.64e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 633 QLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQSQRVGSS-PITTRQLESLIRLTEARARLELREEATREDAEDIIE 711
Cdd:pfam17855 1 ELLRKYIAYAREKIKPKLSEEAREKLVDAYVELRKESTGSGSSiPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAIR 80
|
....*.
gi 148696414 712 IMKHSM 717
Cdd:pfam17855 81 LLKESL 86
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
175-306 |
4.11e-32 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 121.05 E-value: 4.11e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 175 HLKNIRATCYGKYISIRGTVVRVSNIKPLCTNMAFQCAACGEIQSFplpdgKYTLPTKCPVPACRGRSfaPLRSSP-LTV 253
Cdd:pfam17207 1 SIRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGV-----KITEPTKCPNPECGNKD--PFKLVHeKSK 73
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 148696414 254 TLDWQLIKIQElMSDaQREAGRIPRTIECELVHDLVDSCVPGDTVTVTGIVKV 306
Cdd:pfam17207 74 FVDFQKIKIQE-SPE-EVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRV 124
|
|
| MCM8_WHD |
cd22247 |
winged-helix domain (WHD) found in minichromosome maintenance 8 (MCM8) and similar proteins; ... |
742-807 |
8.30e-31 |
|
winged-helix domain (WHD) found in minichromosome maintenance 8 (MCM8) and similar proteins; MCM8 is a DNA helicase that is a component of the MCM8-MCM9 complex, which is involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross-links (ICLs) by homologous recombination (HR). The MCM8-MCM9 complex is also required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting its nuclease activity. This model corresponds to the C-terminal winged-helix domain (WHD) of MCM8, which mediates protein-nucleic acid interaction, as well as protein-protein interaction.
Pssm-ID: 439328 [Multi-domain] Cd Length: 66 Bit Score: 115.27 E-value: 8.30e-31
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 148696414 742 RSTAKRFISALNSIAERTYNNIFQYHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKIYQLQ 807
Cdd:cd22247 1 RKQAKRFVSALQREAERKGNNLFTVDELKQIAKELGLQVDDFDDFIESLNNQGYLLKKGPNLYQLQ 66
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
418-729 |
2.04e-10 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 62.49 E-value: 2.04e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 418 HVLIVGDPGLGKSQMLQAacnVAprgvyvcgnttTSSGL-------TVTL--SK-------DSSSGDFALEAGAL----V 477
Cdd:COG0714 33 HLLLEGVPGVGKTTLAKA---LA-----------RALGLpfiriqfTPDLlpSDilgtyiyDQQTGEFEFRPGPLfanvL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 478 LgdqgicgIDEFDKMGNQHQ-ALLEAMEQQSISLakAGVVCSLPARTSIIAAANPVGghynKART--VSEnlkmgsALLS 554
Cdd:COG0714 99 L-------ADEINRAPPKTQsALLEAMEERQVTI--PGGTYKLPEPFLVIATQNPIE----QEGTypLPE------AQLD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 555 RFdLVFILLDTPNEqhdhllsEHVIAIRAGKQkAVSSATVTRVLSQDSNTSVLEVVSEKPLSERLKvapgeqtdpiphql 634
Cdd:COG0714 160 RF-LLKLYIGYPDA-------EEEREILRRHT-GRHLAEVEPVLSPEELLALQELVRQVHVSEAVL-------------- 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 635 lrkyiGYARQYVHprlstdaaqalqdfylELRKQSQ-RVGSSPittRQLESLIRLTEARARLELREEATREDAEDIIE-I 712
Cdd:COG0714 217 -----DYIVDLVR----------------ATREHPDlRKGPSP---RASIALLRAARALALLDGRDYVTPDDVKAVAGpV 272
|
330
....*....|....*..
gi 148696414 713 MKHSMLGTYSDEFGNLD 729
Cdd:COG0714 273 LKHRLILSPEADAEGVT 289
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
404-562 |
5.84e-07 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 49.84 E-value: 5.84e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 404 YADDKNRIPIRGDPHVLIVGDPGLGKSQMLQA-ACNVAPRGVYVCgnTTTSSGLTVTLSKDSSSGDFALEA--GALVLGD 480
Cdd:cd00009 7 IEALREALELPPPKNLLLYGPPGTGKTTLARAiANELFRPGAPFL--YLNASDLLEGLVVAELFGHFLVRLlfELAEKAK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 481 QGICGIDEFDKMGNQ-HQALLEAMEQQSISLAKagvvcslPARTSIIAAANPvgghynkartvSENLKMGSALLSRFDLV 559
Cdd:cd00009 85 PGVLFIDEIDSLSRGaQNALLRVLETLNDLRID-------RENVRVIGATNR-----------PLLGDLDRALYDRLDIR 146
|
...
gi 148696414 560 FIL 562
Cdd:cd00009 147 IVI 149
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
418-556 |
1.76e-05 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 44.98 E-value: 1.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 418 HVLIVGDPGLGKSQMLQaacnvaprgvYVCGNTTTSSGLTVTLSKDSSSGDF-----------ALEAGALVLGDQ--GIC 484
Cdd:pfam07728 1 GVLLVGPPGTGKTELAE----------RLAAALSNRPVFYVQLTRDTTEEDLfgrrnidpggaSWVDGPLVRAARegEIA 70
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 148696414 485 GIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPA-RTSIIAAANPVGghynkaRTVSEnlkMGSALLSRF 556
Cdd:pfam07728 71 VLDEINRANPDVLnSLLSLLDERRLLLPDGGELVKAAPdGFRLIATMNPLD------RGLNE---LSPALRSRF 135
|
|
| PRK09862 |
PRK09862 |
ATP-dependent protease; |
472-704 |
9.30e-05 |
|
ATP-dependent protease;
Pssm-ID: 182120 [Multi-domain] Cd Length: 506 Bit Score: 45.74 E-value: 9.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 472 EAGALVLGDQGICGIDEFDKMGNQH-QALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPV-GGHY--NKARTVSENL- 546
Cdd:PRK09862 286 GPGEISLAHNGVLFLDELPEFERRTlDALREPIESGQIHLSRTRAKITYPARFQLVAAMNPSpTGHYqgNHNRCTPEQTl 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 547 ----KMGSALLSRFDLVF-ILLDTPNeqhdhLLSEHVIairagkqKAVSSATV-TRVLSQDSNtsvlEVVSEKPLSERLK 620
Cdd:PRK09862 366 rylnRLSGPFLDRFDLSLeIPLPPPG-----ILSKTVV-------PGESSATVkQRVMAARER----QFKRQNKLNAWLD 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 621 VAPgeqtdpiphqlLRKYIgyarqyvhpRLSTDAAQALQDFYLELrkqsqrvgssPITTRQLESLIRLTEARARLELREE 700
Cdd:PRK09862 430 SPE-----------IRQFC---------KLESEDARWLEETLIHL----------GLSIRAWQRLLKVARTIADIDQSDI 479
|
....
gi 148696414 701 ATRE 704
Cdd:PRK09862 480 ITRQ 483
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
419-448 |
5.40e-04 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 42.52 E-value: 5.40e-04
10 20 30
....*....|....*....|....*....|....
gi 148696414 419 VLIVGDPGLGKSQ-MLQAACNVAPRG---VYVCG 448
Cdd:cd01121 85 VLIGGDPGIGKSTlLLQVAARLAQRGgkvLYVSG 118
|
|
| Sms |
COG1066 |
DNA repair protein RadA/Sms, contains AAA+ ATPase domain [Replication, recombination and ... |
419-448 |
1.23e-03 |
|
DNA repair protein RadA/Sms, contains AAA+ ATPase domain [Replication, recombination and repair];
Pssm-ID: 440685 [Multi-domain] Cd Length: 453 Bit Score: 41.96 E-value: 1.23e-03
10 20 30
....*....|....*....|....*....|....
gi 148696414 419 VLIVGDPGLGKSQ-MLQAACNVAPRG---VYVCG 448
Cdd:COG1066 92 VLIGGEPGIGKSTlLLQVAARLAKKGgkvLYVSG 125
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
418-564 |
8.49e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 37.74 E-value: 8.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148696414 418 HVLIVGDPGLGKSQMLQAACNVAPRG----VYVCGNTTTSSGLTVTLSKDSSSGDFALEAGALVLG--------DQGICG 485
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPgggvIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLalalarklKPDVLI 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 148696414 486 IDEFDKMGNQHQALLEAMEQQSISLAKAgvvcSLPARTSIIAAANPvgghynkartvsENLKMGSALLSRFDLVFILLD 564
Cdd:smart00382 84 LDEITSLLDAEQEALLLLLEELRLLLLL----KSEKNLTVILTTND------------EKDLGPALLRRRFDRRIVLLL 146
|
|
| COG2842 |
COG2842 |
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ... |
419-456 |
9.95e-03 |
|
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];
Pssm-ID: 442090 [Multi-domain] Cd Length: 254 Bit Score: 38.78 E-value: 9.95e-03
10 20 30
....*....|....*....|....*....|....*....
gi 148696414 419 VLIVGDPGLGKSQMLQAACNVAPRGVYV-CGNTTTSSGL 456
Cdd:COG2842 53 GVVYGESGVGKTTAAREYANRNPNVIYVtASPSWTSKEL 91
|
|
| |
