|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
92-637 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 728.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 92 KHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRS---VHYCPATKKTIERRYSDLTTLVAFPSSSVYPTkdeennPLE 168
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRAsftCEKCGATLGPEIQSGRETEPTVCPPRECQSPT------PFS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 169 TEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKVKPGDRIQVVGTYRCLP-GKKGCYTSGT--FRTVLIA 245
Cdd:smart00350 75 LNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPyGFKLNTVKGLpvFATYIEA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 246 CNVK----QMSKDIQP----AFSADDIAKIKKFSKtrSKDVFEQLARSLAPSIHGHDYVKKAILCLLLGGVERELENGSH 317
Cdd:smart00350 155 NHVRkldyKRSFEDSSfsvqSLSDEEEEEIRKLSK--DPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMK 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 318 IRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKM 397
Cdd:smart00350 233 IRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKM 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 398 SDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQD 477
Cdd:smart00350 313 DDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERD 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 478 REISDHVLRMHQYRAPGEQDGDalplgssvdilatddpdftqddqqdtriyekhdsllhgtkkkkEKMVSAAFMKKYIHV 557
Cdd:smart00350 393 RELAKHVVDLHRYSHPEEDEAF-------------------------------------------EPPLSQEKLRKYIAY 429
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 558 AK-IIKPTLTQESAAYIAEEYSRLRSQDSmSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAY 636
Cdd:smart00350 430 AReKIKPKLSEEAADKLVKAYVDLRKEDS-QTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESI 508
|
.
gi 53551 637 F 637
Cdd:smart00350 509 I 509
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
281-635 |
0e+00 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 588.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 281 QLARSLAPSIHGHDYVKKAILCLLLGGVERELENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVG 360
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 361 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYG 440
Cdd:cd17754 81 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 441 RYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHQYrapgeqdgdalplgssvdilatddpdftqd 520
Cdd:cd17754 161 RYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------------------------ 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 521 dqqdtriyekhdsllhgtkkkkekmvsAAFMKKYIHVAK-IIKPTLTQESAAYIAEEYSRLRSQDSMSSDTARTSPVTAR 599
Cdd:cd17754 211 ---------------------------IKFLRKYIHYAKeRIKPKLTQEAAEYIAEEYADLRNDDNTKTDKARTSPITAR 263
|
330 340 350
....*....|....*....|....*....|....*.
gi 53551 600 TLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 635
Cdd:cd17754 264 TLETLIRLATAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
15-640 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 533.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 15 YQNKVRELISDNQYR--LIVSVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIdatYAKQYEEFYIGLEGSFgsK 92
Cdd:COG1241 18 YRDEILELAQEYPEKrsLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLEP---YDVSLGDAHVRITNLP--E 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 93 HVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPA--TKKTIERRYSDLTtlvafpsssvYPTKDEE---NNPL 167
Cdd:COG1241 93 TVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRcgTETYVPQTGEKLQ----------EPHECPGcgrQGPF 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 168 ETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKVKPGDRIQVVGTYRCLPGKKGCYTSGTFRTVLIACN 247
Cdd:COG1241 163 KLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRGKSTIFDLYLEANS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 248 VKQMSKDIQP-AFSADDIAKIKKFSKtrSKDVFEQLARSLAPSIHGHDYVKKAILCLLLGGVERELENGSHIRGDINILL 326
Cdd:COG1241 243 IEVEEKEFEEiEITEEDEEKIKELSK--DPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSRIRGDIHILL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 327 IGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQE-TGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAI 405
Cdd:COG1241 321 VGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGRWTLEAGALVLADGGLACIDELDKMREEDRSAL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 406 HEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVL 485
Cdd:COG1241 401 HEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARHIL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 486 RMHqyrapgeqdgdalplgssvdilatddpdftqddqqdtRIYEKHDSLLHGTKKKKEKMVSAAFMKKYIHVAK-IIKPT 564
Cdd:COG1241 481 KVH-------------------------------------RAGELLEQEIEEETEEVKPEIDPDLLRKYIAYARrNVFPV 523
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 53551 565 LTQESAAYIAEEYSRLRSQDSMSSDTArtsPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYaYFKKV 640
Cdd:COG1241 524 LTEEAKDLIEDFYVDMRKKGEDEDSPV---PITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDS-CLKDV 595
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
8-640 |
1.32e-168 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 502.92 E-value: 1.32e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 8 DEEDQGIYQNKVRELISDNQYRLIVSVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFYIGLEG 87
Cdd:NF040949 14 DSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEYAEEVAKFHVRFRN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 88 SFgsKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPtKDEENNPL 167
Cdd:NF040949 94 LP--RTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWPEEEEESYEIVEPPTVCP-VCGKPGSF 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 168 ETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKVKPGDRIQVVGTYRCLPG---KKGcyTSGTFRTVLI 244
Cdd:NF040949 171 RLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDsslKKG--SRPIFKNYIE 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 245 ACNVKQMSKDIQP-AFSADDIAKIKKFSKtrSKDVFEQLARSLAPSIHGHDYVKKAILCLLLGGVERELENGSHIRGDIN 323
Cdd:NF040949 249 ANHIEVSQKELEEvEITEEDEEKILELAK--DPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGTRIRGDIH 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 324 ILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRT 403
Cdd:NF040949 327 VLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDKMREEDRS 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 404 AIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDH 483
Cdd:NF040949 407 AIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEERDRRLARH 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 484 VLRMHQyrapgeqdgdalplgssvdilatddpdftqddqqdtriyekhdsllhgTKKKKEKMVSAAFMKKYIHVA-KIIK 562
Cdd:NF040949 487 ILDVHS------------------------------------------------GKEKVKPEIDPDLLKKYIAYArKYVR 518
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 53551 563 PTLTQESAAYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELvQYAYFKKV 640
Cdd:NF040949 519 PKLTEEAKKLIEDFYVEMRKSSKSSEDPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRL-MLAFLESV 595
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
263-488 |
1.90e-129 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 384.96 E-value: 1.90e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 263 DIAKIKKFSKtrSKDVFEQLARSLAPSIHGHDYVKKAILCLLLGGVERELENGSHIRGDINILLIGDPSVAKSQLLRYVL 342
Cdd:pfam00493 1 DEEEIKELAK--RPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 343 CTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIH 422
Cdd:pfam00493 79 KIAPRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIV 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 53551 423 ARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMH 488
Cdd:pfam00493 159 ATLNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
96-642 |
2.29e-79 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 274.18 E-value: 2.29e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 96 PRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVafpssSVYPTKDEENNPL-------- 167
Cdd:PTZ00111 218 VGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKIGLNDYQPCTCEH-----YEYVIQGEVNEPLlcnecnsk 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 168 ---ETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDK--------------------VKPGDRIQVVG-- 222
Cdd:PTZ00111 293 ytfELNHNMCVYSTKKIVKLLQSNSSLNNPDKDGLDNSVDNSGLNGEiymkdnevinlnlyddlidsVKTGDRVTVVGil 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 223 ---------TYRCLPGKKGCYTSGTFRTVLIACNVKQMSKDI-----QPAFSADDIAKIKKFSktRSKDVFEQLARSLAP 288
Cdd:PTZ00111 373 kvtpirtstTRRTLKSLYTYFVNVIHVKVINSTNANQPEKGLkylgnENDFSDLQVYKILELS--RNPMIYRILLDSFAP 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 289 SIHGHDYVKKAILCLLLGGVERELENGSHI---------RGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 359
Cdd:PTZ00111 451 SIKARNNVKIGLLCQLFSGNKNSSDFNKSPdacykvdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSV 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 360 GLTAAVT-TDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPV 438
Cdd:PTZ00111 531 GLTASIKfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPI 610
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 439 YGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRmhQYRAPGEQDGDAlplgssvdilatddpDFT 518
Cdd:PTZ00111 611 NSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK--DFLLPHMTGSGN---------------DED 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 519 QDDQQDTRIYEkhDSLLHgtKKKKEKMVSAAFMKKYIHVAKI-IKPTLTQESAAYIAEEYSRLRSQDSMSSDT------- 590
Cdd:PTZ00111 674 TYDRSNTMHVE--DESLR--SEKDYNKNDLDMLRMYIKFSKLhCFPKLSDEAKKVITREYVKMRQGNFQTSNLdelehaq 749
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 53551 591 -------------ARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLE 642
Cdd:PTZ00111 750 edddddlyyqssgTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQSLVD 814
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
7-87 |
2.03e-14 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 69.24 E-value: 2.03e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 7 DDEEDQGIYQNKVRELISDNQYRLIVSVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASI--DATYAKQYEEFYIG 84
Cdd:pfam14551 13 EDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKELseDPDYAEEEKEFQVR 92
|
...
gi 53551 85 LEG 87
Cdd:pfam14551 93 FYN 95
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
92-637 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 728.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 92 KHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRS---VHYCPATKKTIERRYSDLTTLVAFPSSSVYPTkdeennPLE 168
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRAsftCEKCGATLGPEIQSGRETEPTVCPPRECQSPT------PFS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 169 TEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKVKPGDRIQVVGTYRCLP-GKKGCYTSGT--FRTVLIA 245
Cdd:smart00350 75 LNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPyGFKLNTVKGLpvFATYIEA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 246 CNVK----QMSKDIQP----AFSADDIAKIKKFSKtrSKDVFEQLARSLAPSIHGHDYVKKAILCLLLGGVERELENGSH 317
Cdd:smart00350 155 NHVRkldyKRSFEDSSfsvqSLSDEEEEEIRKLSK--DPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMK 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 318 IRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKM 397
Cdd:smart00350 233 IRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKM 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 398 SDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQD 477
Cdd:smart00350 313 DDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERD 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 478 REISDHVLRMHQYRAPGEQDGDalplgssvdilatddpdftqddqqdtriyekhdsllhgtkkkkEKMVSAAFMKKYIHV 557
Cdd:smart00350 393 RELAKHVVDLHRYSHPEEDEAF-------------------------------------------EPPLSQEKLRKYIAY 429
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 558 AK-IIKPTLTQESAAYIAEEYSRLRSQDSmSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAY 636
Cdd:smart00350 430 AReKIKPKLSEEAADKLVKAYVDLRKEDS-QTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESI 508
|
.
gi 53551 637 F 637
Cdd:smart00350 509 I 509
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
281-635 |
0e+00 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 588.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 281 QLARSLAPSIHGHDYVKKAILCLLLGGVERELENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVG 360
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 361 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYG 440
Cdd:cd17754 81 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 441 RYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHQYrapgeqdgdalplgssvdilatddpdftqd 520
Cdd:cd17754 161 RYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------------------------ 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 521 dqqdtriyekhdsllhgtkkkkekmvsAAFMKKYIHVAK-IIKPTLTQESAAYIAEEYSRLRSQDSMSSDTARTSPVTAR 599
Cdd:cd17754 211 ---------------------------IKFLRKYIHYAKeRIKPKLTQEAAEYIAEEYADLRNDDNTKTDKARTSPITAR 263
|
330 340 350
....*....|....*....|....*....|....*.
gi 53551 600 TLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 635
Cdd:cd17754 264 TLETLIRLATAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
15-640 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 533.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 15 YQNKVRELISDNQYR--LIVSVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIdatYAKQYEEFYIGLEGSFgsK 92
Cdd:COG1241 18 YRDEILELAQEYPEKrsLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLEP---YDVSLGDAHVRITNLP--E 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 93 HVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPA--TKKTIERRYSDLTtlvafpsssvYPTKDEE---NNPL 167
Cdd:COG1241 93 TVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRcgTETYVPQTGEKLQ----------EPHECPGcgrQGPF 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 168 ETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKVKPGDRIQVVGTYRCLPGKKGCYTSGTFRTVLIACN 247
Cdd:COG1241 163 KLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRGKSTIFDLYLEANS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 248 VKQMSKDIQP-AFSADDIAKIKKFSKtrSKDVFEQLARSLAPSIHGHDYVKKAILCLLLGGVERELENGSHIRGDINILL 326
Cdd:COG1241 243 IEVEEKEFEEiEITEEDEEKIKELSK--DPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSRIRGDIHILL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 327 IGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQE-TGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAI 405
Cdd:COG1241 321 VGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGRWTLEAGALVLADGGLACIDELDKMREEDRSAL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 406 HEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVL 485
Cdd:COG1241 401 HEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARHIL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 486 RMHqyrapgeqdgdalplgssvdilatddpdftqddqqdtRIYEKHDSLLHGTKKKKEKMVSAAFMKKYIHVAK-IIKPT 564
Cdd:COG1241 481 KVH-------------------------------------RAGELLEQEIEEETEEVKPEIDPDLLRKYIAYARrNVFPV 523
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 53551 565 LTQESAAYIAEEYSRLRSQDSMSSDTArtsPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYaYFKKV 640
Cdd:COG1241 524 LTEEAKDLIEDFYVDMRKKGEDEDSPV---PITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDS-CLKDV 595
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
8-640 |
1.32e-168 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 502.92 E-value: 1.32e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 8 DEEDQGIYQNKVRELISDNQYRLIVSVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFYIGLEG 87
Cdd:NF040949 14 DSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEYAEEVAKFHVRFRN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 88 SFgsKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPtKDEENNPL 167
Cdd:NF040949 94 LP--RTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWPEEEEESYEIVEPPTVCP-VCGKPGSF 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 168 ETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKVKPGDRIQVVGTYRCLPG---KKGcyTSGTFRTVLI 244
Cdd:NF040949 171 RLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDsslKKG--SRPIFKNYIE 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 245 ACNVKQMSKDIQP-AFSADDIAKIKKFSKtrSKDVFEQLARSLAPSIHGHDYVKKAILCLLLGGVERELENGSHIRGDIN 323
Cdd:NF040949 249 ANHIEVSQKELEEvEITEEDEEKILELAK--DPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGTRIRGDIH 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 324 ILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRT 403
Cdd:NF040949 327 VLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDKMREEDRS 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 404 AIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDH 483
Cdd:NF040949 407 AIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEERDRRLARH 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 484 VLRMHQyrapgeqdgdalplgssvdilatddpdftqddqqdtriyekhdsllhgTKKKKEKMVSAAFMKKYIHVA-KIIK 562
Cdd:NF040949 487 ILDVHS------------------------------------------------GKEKVKPEIDPDLLKKYIAYArKYVR 518
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 53551 563 PTLTQESAAYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELvQYAYFKKV 640
Cdd:NF040949 519 PKLTEEAKKLIEDFYVEMRKSSKSSEDPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRL-MLAFLESV 595
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
282-633 |
6.43e-141 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 417.90 E-value: 6.43e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 282 LARSLAPSIHGHDYVKKAILCLLLGGVERELENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGL 361
Cdd:cd17706 2 LADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 362 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGR 441
Cdd:cd17706 82 TAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 442 YDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHQYRAPGEQDgdalplgssvdilatddpdftqdd 521
Cdd:cd17706 162 YNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDPEEQV------------------------ 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 522 qqdtriyekhdsllhgTKKKKEKMVSAAFMKKYIHVAKIIKPTLTQESAAYIAEEYSRLRSQdsmsSDTARTSPVTARTL 601
Cdd:cd17706 218 ----------------KPEEDGIPIDIELLRKYILYARQIHPKISEEAREKLVRWYVELRKE----SERRSTIPITARQL 277
|
330 340 350
....*....|....*....|....*....|..
gi 53551 602 ETLIRLATAHAKARMSKTVDLQDAEEAVELVQ 633
Cdd:cd17706 278 ESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVR 309
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
263-488 |
1.90e-129 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 384.96 E-value: 1.90e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 263 DIAKIKKFSKtrSKDVFEQLARSLAPSIHGHDYVKKAILCLLLGGVERELENGSHIRGDINILLIGDPSVAKSQLLRYVL 342
Cdd:pfam00493 1 DEEEIKELAK--RPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 343 CTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIH 422
Cdd:pfam00493 79 KIAPRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIV 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 53551 423 ARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMH 488
Cdd:pfam00493 159 ATLNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
282-635 |
2.09e-124 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 375.21 E-value: 2.09e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 282 LARSLAPSIHGHDYVKKAILCLLLGGVERElENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGL 361
Cdd:cd17758 2 LAASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 362 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGR 441
Cdd:cd17758 81 TAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 442 YDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHQYrapgeqdgdalplgssvdilaTDDPDftqdd 521
Cdd:cd17758 161 YNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQH---------------------NKQPD----- 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 522 qqdtriyekhdsllhgtkkKKEKMVSAAFMKKYIHVAKIIKPTLTQESAAYIAEEYSRLRSQDSMSSDTARTSPvtaRTL 601
Cdd:cd17758 215 -------------------SDFEPLDPKLLRAYIALAKRKRPTVPPALADYIVQAYVEMRQEAKRSKDFTFTTP---RTL 272
|
330 340 350
....*....|....*....|....*....|....
gi 53551 602 ETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 635
Cdd:cd17758 273 LAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
282-633 |
5.76e-119 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 361.31 E-value: 5.76e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 282 LARSLAPSIHGHDYVKKAILCLLLGGVERELENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGL 361
Cdd:cd17756 2 ISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 362 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGR 441
Cdd:cd17756 82 TASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 442 YDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHQYRAPGEQDGDAlplgssvdilatddpdftqdd 521
Cdd:cd17756 162 YDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQSQEN--------------------- 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 522 qqdtriyekhdsllhgtkkkkEKMVSAAFMKKYIHVAKI-IKPTLTQESAAYIAEEYSRLRS---QDSMSSDTARTSPVT 597
Cdd:cd17756 221 ---------------------EGEIPISKLKRYIAYCRAkCAPRLSEEAAEKLSNHYVTIRKdvrQNELESDNRSSIPIT 279
|
330 340 350
....*....|....*....|....*....|....*.
gi 53551 598 ARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQ 633
Cdd:cd17756 280 VRQLEAIIRISESLAKMELSPIATEKHVEEAIRLFQ 315
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
282-632 |
4.26e-117 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 356.29 E-value: 4.26e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 282 LARSLAPSIHGHDYVKKAILCLLLGGVERELENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGL 361
Cdd:cd17757 2 LVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 362 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGR 441
Cdd:cd17757 82 TAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 442 YDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHQYRApgeqdgdalplgssvdilATDDPDFTQDD 521
Cdd:cd17757 162 YDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKRE------------------EAIEPPFTAEQ 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 522 qqdtriyekhdsllhgtkkkkekmvsaafMKKYIHVAKIIKPTLTQESAAYIAEEYSRLRsQDSMSSDTARTSPVTARTL 601
Cdd:cd17757 224 -----------------------------LKRYIAYARTFKPKLTKEAKDELVEQYKELR-QDDASGSTRSSYRITVRQL 273
|
330 340 350
....*....|....*....|....*....|.
gi 53551 602 ETLIRLATAHAKARMSKTVDLQDAEEAVELV 632
Cdd:cd17757 274 ESLIRLSEAIARLHCSDEVTPEHVEEAARLL 304
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
280-633 |
9.62e-114 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 347.52 E-value: 9.62e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 280 EQLARSLAPSIHGHDYVKKAILCLLLGGVERELENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 359
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 360 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVY 439
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 440 GRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHQyrapgeqdgdalpLGSSVDILATDDPDftq 519
Cdd:cd17761 161 GRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHS-------------GGEMREIKPEIDPD--- 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 520 ddqqdtriyekhdsllhgtkkkkekmvsaaFMKKYIHVA-KIIKPTLTQESAAYIAEEYSRLRSQdsmSSDTARTSPVTA 598
Cdd:cd17761 225 ------------------------------LLRKYIAYArKNVRPVLTEEAKQLIKDFYVEMRKS---GQETPSPVPITA 271
|
330 340 350
....*....|....*....|....*....|....*
gi 53551 599 RTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQ 633
Cdd:cd17761 272 RQLEALVRLSEASARMRLSQEVTLEDAERAIRIML 306
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
282-635 |
3.50e-109 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 335.95 E-value: 3.50e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 282 LARSLAPSIHGHDYVKKAILCLLLGGVERELEN-GSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVG 360
Cdd:cd17755 2 LARSIAPSIYELEDVKKGILLQLFGGTRKDFTKtGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAVG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 361 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYG 440
Cdd:cd17755 82 LTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIGS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 441 RYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHQYRAPGEQDGDALPlgssvdilatddpdftqd 520
Cdd:cd17755 162 RYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTPEHIQDEVLD------------------ 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 521 dqqdtriyekhdsllhgtkkkkekmvsAAFMKKYIHVAKI-IKPTLTQESAAYIAEEYSRLRsqdSMSSDTARTSPVTAR 599
Cdd:cd17755 224 ---------------------------VEVLTDYISYAREhIHPKLSEEAAQELVQAYVDMR---KMGSDARKRITATPR 273
|
330 340 350
....*....|....*....|....*....|....*.
gi 53551 600 TLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 635
Cdd:cd17755 274 QLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
285-632 |
1.64e-107 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 332.11 E-value: 1.64e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 285 SLAPSIHGHDYVKKAILCLLLGGVERELENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAA 364
Cdd:cd17753 5 SIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVGLTAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 365 VTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQ 444
Cdd:cd17753 85 VRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGGRYNP 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 445 YKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHqyrapgeqdgdalplgssvdilATDDPDFTQDDQQD 524
Cdd:cd17753 165 TLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSH----------------------VRSHPENDEDREGE 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 525 TRIYEKHDSllhgtKKKKEKMVSAAFMKKYIHVAKI-IKPTLTQESAAYIAEEYSRLRsQDSMSSDTArtsPVTARTLET 603
Cdd:cd17753 223 EEKNQRQRP-----KETKVEPIPQELLRKYIHYAREkVRPKLNQMDMDKVSRVYADLR-KESMATGSL---PITVRHLES 293
|
330 340
....*....|....*....|....*....
gi 53551 604 LIRLATAHAKARMSKTVDLQDAEEAVELV 632
Cdd:cd17753 294 IIRISEAHAKMHLREYVSEEDVDMAIRVM 322
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
96-642 |
2.29e-79 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 274.18 E-value: 2.29e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 96 PRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVafpssSVYPTKDEENNPL-------- 167
Cdd:PTZ00111 218 VGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKIGLNDYQPCTCEH-----YEYVIQGEVNEPLlcnecnsk 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 168 ---ETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDK--------------------VKPGDRIQVVG-- 222
Cdd:PTZ00111 293 ytfELNHNMCVYSTKKIVKLLQSNSSLNNPDKDGLDNSVDNSGLNGEiymkdnevinlnlyddlidsVKTGDRVTVVGil 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 223 ---------TYRCLPGKKGCYTSGTFRTVLIACNVKQMSKDI-----QPAFSADDIAKIKKFSktRSKDVFEQLARSLAP 288
Cdd:PTZ00111 373 kvtpirtstTRRTLKSLYTYFVNVIHVKVINSTNANQPEKGLkylgnENDFSDLQVYKILELS--RNPMIYRILLDSFAP 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 289 SIHGHDYVKKAILCLLLGGVERELENGSHI---------RGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 359
Cdd:PTZ00111 451 SIKARNNVKIGLLCQLFSGNKNSSDFNKSPdacykvdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSV 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 360 GLTAAVT-TDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPV 438
Cdd:PTZ00111 531 GLTASIKfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPI 610
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 439 YGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRmhQYRAPGEQDGDAlplgssvdilatddpDFT 518
Cdd:PTZ00111 611 NSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK--DFLLPHMTGSGN---------------DED 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 519 QDDQQDTRIYEkhDSLLHgtKKKKEKMVSAAFMKKYIHVAKI-IKPTLTQESAAYIAEEYSRLRSQDSMSSDT------- 590
Cdd:PTZ00111 674 TYDRSNTMHVE--DESLR--SEKDYNKNDLDMLRMYIKFSKLhCFPKLSDEAKKVITREYVKMRQGNFQTSNLdelehaq 749
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 53551 591 -------------ARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLE 642
Cdd:PTZ00111 750 edddddlyyqssgTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQSLVD 814
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
282-635 |
6.29e-73 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 240.14 E-value: 6.29e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 282 LARSLAPSIHGHDYVKKAILCLLLGGVERELENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGL 361
Cdd:cd17760 2 ILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 362 TaaVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPvYGR 441
Cdd:cd17760 82 T--VTAVKDGGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 442 YDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLrmhqyrapgEQDGDAlplgssvdilatddpdftqdd 521
Cdd:cd17760 159 YDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFIL---------ENKGEP--------------------- 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 522 qqdtriyekhdsllhgtkKKKEKMVSAAFMKKYIHVAKIIKPTLTQESAAyIAEEYSRLRSQdsmsSDTARTSPVTARTL 601
Cdd:cd17760 209 ------------------SKSSKLWSMEKMRTYFCLIKNLRPVLSDEANA-ILLRYYQLQRQ----SDCRNAARTTIRML 265
|
330 340 350
....*....|....*....|....*....|....
gi 53551 602 ETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 635
Cdd:cd17760 266 ESLIRLAEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
282-635 |
1.00e-67 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 225.88 E-value: 1.00e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 282 LARSLAPSIHGHDYVKKAILCLLLGGVER--ELENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 359
Cdd:cd17759 2 IVNSLCPAIYGHELVKAGLLLSLFGGKQKyaDDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTTS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 360 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDmDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVY 439
Cdd:cd17759 82 GLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGS-QHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPVG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 440 GRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHvlrmHQyrapgeqdgdalplgssvdilatddpdftq 519
Cdd:cd17759 161 GHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEH----HQ------------------------------ 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 520 ddqqdtriyekhdsllhgtkkkkekmvsaaFMKKYIHVAK-IIKPTLTQESAAYIAEEYSRLRSQdsmsSDTARTSPVTA 598
Cdd:cd17759 207 ------------------------------LLRKYISYARqYVNPVLSKDASEALQEFYLELRKQ----NQLADSSPITT 252
|
330 340 350
....*....|....*....|....*....|....*..
gi 53551 599 RTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 635
Cdd:cd17759 253 RQLESLIRLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
97-228 |
3.78e-36 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 132.61 E-value: 3.78e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 97 RTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPtkdeenNPLETEygLSVY 176
Cdd:pfam17207 3 RDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVKITEPTKCPNPECGNKDP------FKLVHE--KSKF 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 53551 177 KDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKVKPGDRIQVVGTYRCLP 228
Cdd:pfam17207 75 VDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVVP 126
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
550-633 |
1.63e-22 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 92.22 E-value: 1.63e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 550 FMKKYIHVAKI-IKPTLTQESAAYIAEEYSRLRSqdsMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEA 628
Cdd:pfam17855 2 LLRKYIAYAREkIKPKLSEEAREKLVDAYVELRK---ESTGSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEA 78
|
....*
gi 53551 629 VELVQ 633
Cdd:pfam17855 79 IRLLK 83
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
7-87 |
2.03e-14 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 69.24 E-value: 2.03e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 7 DDEEDQGIYQNKVRELISDNQYRLIVSVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASI--DATYAKQYEEFYIG 84
Cdd:pfam14551 13 EDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKELseDPDYAEEEKEFQVR 92
|
...
gi 53551 85 LEG 87
Cdd:pfam14551 93 FYN 95
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
280-495 |
4.44e-07 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 52.48 E-value: 4.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 280 EQLARSLAPSIHGHDYVKKAIL-CLLLGGverelengshirgdiNILLIGDPSVAKSQLLR---YVLCTAPRAIPTTgrg 355
Cdd:COG0714 4 ARLRAEIGKVYVGQEELIELVLiALLAGG---------------HLLLEGVPGVGKTTLAKalaRALGLPFIRIQFT--- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 356 ssgVGLTAA-VT----TDQETGERRLEAGAmVLAdrGVVCIDEFDKMSDmdRT--AIHEVMEQGRVTIakAGIHARLNAR 428
Cdd:COG0714 66 ---PDLLPSdILgtyiYDQQTGEFEFRPGP-LFA--NVLLADEINRAPP--KTqsALLEAMEERQVTI--PGGTYKLPEP 135
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 429 CSVLAAANPVygrydqyktpmENIG---LQDSLLSRFdLLFIMLDQMDPEQDREIsdhvLRMHQYRAPGE 495
Cdd:COG0714 136 FLVIATQNPI-----------EQEGtypLPEAQLDRF-LLKLYIGYPDAEEEREI----LRRHTGRHLAE 189
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
323-462 |
6.01e-05 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 43.44 E-value: 6.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 323 NILLIGDPSVAKSQLLRYV---LCTAPRAIpttgrgssgVGLTAAVTTDQETGERRLEAGAMVLADR---------GVVC 390
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLaaaLSNRPVFY---------VQLTRDTTEEDLFGRRNIDPGGASWVDGplvraaregEIAV 71
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 53551 391 IDEFDKMSDMDRTAIHEVMEQGRVTIAKAG--IHARLNARcSVLAAANPVYGRydqyktPMEnigLQDSLLSRF 462
Cdd:pfam07728 72 LDEINRANPDVLNSLLSLLDERRLLLPDGGelVKAAPDGF-RLIATMNPLDRG------LNE---LSPALRSRF 135
|
|
| Mg_chelatase |
pfam01078 |
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ... |
379-437 |
1.19e-04 |
|
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.
Pssm-ID: 426032 [Multi-domain] Cd Length: 207 Bit Score: 44.06 E-value: 1.19e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 53551 379 GAMVLADRGVVCIDEfdkMSDMDRTAI---HEVMEQGRVTIAKAGIHARLNARCSVLAAANP 437
Cdd:pfam01078 100 GEISLAHNGVLFLDE---LPEFKRRVLeslRQPLEDGEITISRARAKVTFPARFQLVAAMNP 158
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
323-468 |
5.72e-04 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 40.98 E-value: 5.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53551 323 NILLIGDPSVAKSQLLRYVLCTAPRaipttgRGSSGVGLTAAVTT-------DQETGERRLEAGAMVLADRGVVCIDEFD 395
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFR------PGAPFLYLNASDLLeglvvaeLFGHFLVRLLFELAEKAKPGVLFIDEID 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 53551 396 KMSDMDRTAIHEVMEQGRVTIAKagiharlNARCSVLAAANpvygrydqyktPMENIGLQDSLLSRFDLLFIM 468
Cdd:cd00009 95 SLSRGAQNALLRVLETLNDLRID-------RENVRVIGATN-----------RPLLGDLDRALYDRLDIRIVI 149
|
|
| YifB |
COG0606 |
Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational ... |
379-437 |
1.35e-03 |
|
Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440371 [Multi-domain] Cd Length: 502 Bit Score: 41.95 E-value: 1.35e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 53551 379 GAMVLADRGVVCIDEfdkMSDMDRTAIhEV----MEQGRVTIAKAGIHARLNARCSVLAAANP 437
Cdd:COG0606 290 GEISLAHNGVLFLDE---LPEFSRRVL-EAlrqpLEDGEVTISRANGSVTYPARFQLVAAMNP 348
|
|
| |
