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Conserved domains on  [gi|26340564|dbj|BAC33944|]
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unnamed protein product [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ASD2 super family cl07345
Apx/Shroom domain ASD2; This region is found in the actin binding protein Shroom which ...
 1-121 4.15e-72

Apx/Shroom domain ASD2; This region is found in the actin binding protein Shroom which mediates apical contriction in epithelial cells and is required for neural tube closure.


The actual alignment was detected with superfamily member pfam08687:

Pssm-ID: 462561 [Multi-domain]  Cd Length: 290  Bit Score: 216.74  E-value: 4.15e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26340564     1 MFIGDLDKVVNLLLSLSGRLARVENALNNLDDNPSPGDRQSLLEKQRVLTQQHEDAKELKENLDRRERIVFDILATYLSE 80
Cdd:pfam08687 170 MFIGDLEKVVSLLLSLSGRLARVENALSSLDSDADAEERQSLLEKRRLLLRQLEDAKELKENLDRRERVVSGILARYLTA 249

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 26340564    81 ENLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKCLFDSL 121
Cdd:pfam08687 250 EQLQDYRHFVKMKAALLIEQRELDEKIKLGEEQLKALKESL 290
 
Name Accession Description Interval E-value
ASD2 pfam08687
Apx/Shroom domain ASD2; This region is found in the actin binding protein Shroom which ...
 1-121 4.15e-72

Apx/Shroom domain ASD2; This region is found in the actin binding protein Shroom which mediates apical contriction in epithelial cells and is required for neural tube closure.


Pssm-ID: 462561 [Multi-domain]  Cd Length: 290  Bit Score: 216.74  E-value: 4.15e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26340564     1 MFIGDLDKVVNLLLSLSGRLARVENALNNLDDNPSPGDRQSLLEKQRVLTQQHEDAKELKENLDRRERIVFDILATYLSE 80
Cdd:pfam08687 170 MFIGDLEKVVSLLLSLSGRLARVENALSSLDSDADAEERQSLLEKRRLLLRQLEDAKELKENLDRRERVVSGILARYLTA 249

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 26340564    81 ENLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKCLFDSL 121
Cdd:pfam08687 250 EQLQDYRHFVKMKAALLIEQRELDEKIKLGEEQLKALKESL 290
 
Name Accession Description Interval E-value
ASD2 pfam08687
Apx/Shroom domain ASD2; This region is found in the actin binding protein Shroom which ...
 1-121 4.15e-72

Apx/Shroom domain ASD2; This region is found in the actin binding protein Shroom which mediates apical contriction in epithelial cells and is required for neural tube closure.


Pssm-ID: 462561 [Multi-domain]  Cd Length: 290  Bit Score: 216.74  E-value: 4.15e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 26340564     1 MFIGDLDKVVNLLLSLSGRLARVENALNNLDDNPSPGDRQSLLEKQRVLTQQHEDAKELKENLDRRERIVFDILATYLSE 80
Cdd:pfam08687 170 MFIGDLEKVVSLLLSLSGRLARVENALSSLDSDADAEERQSLLEKRRLLLRQLEDAKELKENLDRRERVVSGILARYLTA 249

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 26340564    81 ENLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKCLFDSL 121
Cdd:pfam08687 250 EQLQDYRHFVKMKAALLIEQRELDEKIKLGEEQLKALKESL 290
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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