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Conserved domains on  [gi|187956501|gb|AAI50631|]
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Phosphatase and actin regulator 2 [Homo sapiens]

Protein Classification

RPEL repeat-containing protein( domain architecture ID 10499653)

RPEL repeat-containing protein such as Phactrs 1-4, a family of protein phosphatase 1 and actin regulatory proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
516-540 9.22e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


:

Pssm-ID: 128947  Cd Length: 26  Bit Score: 42.46  E-value: 9.22e-06
                           10        20
                   ....*....|....*....|....*
gi 187956501   516 KLVRRLSQRPTTEELEQRNILKQKN 540
Cdd:smart00707   2 VLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 62-83 1.85e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


:

Pssm-ID: 460677  Cd Length: 24  Bit Score: 38.79  E-value: 1.85e-04
                          10        20
                  ....*....|....*....|..
gi 187956501   62 LERKISTRQSREELIRRGVLKE 83
Cdd:pfam02755   2 LERKLSHRPTREELVERNILPE 23
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
553-578 2.23e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


:

Pssm-ID: 128947  Cd Length: 26  Bit Score: 38.61  E-value: 2.23e-04
                           10        20
                   ....*....|....*....|....*.
gi 187956501   553 RRLSRKLSLRPTVAELQARRILRFNE 578
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
477-502 4.35e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


:

Pssm-ID: 128947  Cd Length: 26  Bit Score: 37.84  E-value: 4.35e-04
                           10        20
                   ....*....|....*....|....*.
gi 187956501   477 DTLAIKLGNRPSKKELEDKNILQRTS 502
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
 
Name Accession Description Interval E-value
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
516-540 9.22e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 42.46  E-value: 9.22e-06
                           10        20
                   ....*....|....*....|....*
gi 187956501   516 KLVRRLSQRPTTEELEQRNILKQKN 540
Cdd:smart00707   2 VLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 516-537 1.12e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 39.56  E-value: 1.12e-04
                          10        20
                  ....*....|....*....|..
gi 187956501  516 KLVRRLSQRPTTEELEQRNILK 537
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILP 22
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 62-83 1.85e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 38.79  E-value: 1.85e-04
                          10        20
                  ....*....|....*....|..
gi 187956501   62 LERKISTRQSREELIRRGVLKE 83
Cdd:pfam02755   2 LERKLSHRPTREELVERNILPE 23
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
553-578 2.23e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 38.61  E-value: 2.23e-04
                           10        20
                   ....*....|....*....|....*.
gi 187956501   553 RRLSRKLSLRPTVAELQARRILRFNE 578
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
60-85 3.54e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 37.84  E-value: 3.54e-04
                           10        20
                   ....*....|....*....|....*.
gi 187956501    60 AVLERKISTRQSREELIRRGVLKELP 85
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
477-502 4.35e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 37.84  E-value: 4.35e-04
                           10        20
                   ....*....|....*....|....*.
gi 187956501   477 DTLAIKLGNRPSKKELEDKNILQRTS 502
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
 
Name Accession Description Interval E-value
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
516-540 9.22e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 42.46  E-value: 9.22e-06
                           10        20
                   ....*....|....*....|....*
gi 187956501   516 KLVRRLSQRPTTEELEQRNILKQKN 540
Cdd:smart00707   2 VLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 516-537 1.12e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 39.56  E-value: 1.12e-04
                          10        20
                  ....*....|....*....|..
gi 187956501  516 KLVRRLSQRPTTEELEQRNILK 537
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILP 22
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 62-83 1.85e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 38.79  E-value: 1.85e-04
                          10        20
                  ....*....|....*....|..
gi 187956501   62 LERKISTRQSREELIRRGVLKE 83
Cdd:pfam02755   2 LERKLSHRPTREELVERNILPE 23
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
553-578 2.23e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 38.61  E-value: 2.23e-04
                           10        20
                   ....*....|....*....|....*.
gi 187956501   553 RRLSRKLSLRPTVAELQARRILRFNE 578
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
60-85 3.54e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 37.84  E-value: 3.54e-04
                           10        20
                   ....*....|....*....|....*.
gi 187956501    60 AVLERKISTRQSREELIRRGVLKELP 85
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
477-502 4.35e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 37.84  E-value: 4.35e-04
                           10        20
                   ....*....|....*....|....*.
gi 187956501   477 DTLAIKLGNRPSKKELEDKNILQRTS 502
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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