5O2C,2LRU


Conserved Protein Domain Family
OSR1_C
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pfam12202: OSR1_C 
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Oxidative-stress-responsive kinase 1 C-terminal domain
This domain family is found in eukaryotes, and is approximately 40 amino acids in length. The family is found in association with pfam00069. There is a single completely conserved residue F that may be functionally important. OSR1 is involved in the signalling cascade which activates Na/K/2Cl cotransporter during osmotic stress. This domain is the C terminal domain of OSR1 which recognizes a motif (Arg-Phe-Xaa-Val) on the OSR1-activating protein WNK1.
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Statistics
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PSSM-Id: 463491
Aligned: 26 rows
Threshold Bit Score: 76.533
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5O2C_A        306 LALRLWVEDpkklkgKHKDNEAIEFSFNLETDTPEEVAYEMVKSGFFHESDSKAVAKSIRDRVT 369 
XP_002412500  182 VELRLRVLDpkkrkdKHRENEAIQFEFHVENDNPDEIAKAMALTGIIMEEDARIVSMLIRNQIA 245 
XP_015795029  352 IEFRLIVTDpkkrkdKYKENEAIQFYFEIDKDNADEVALALVATGFLMEEDVRTVALLIRNQIS 415 
EFN65329      905 VEFRLRVLDpkkrsnKHKENEAIQFDFDIQADNAEEVALEMAKSSLILEEDAKAVAKMLKSQIT 968 
XP_003276359  426 LALRLWVEDpkklkgKHKDNEAIEFSFNLETDTPEEVAYEMVKSGFFHESDSKAVAKSIRDRVT 489 
ELK01464      123 LKLWLRMEDarr-ggRPRDNQAIEFLFQLGRDAAEEVAQEMVALGLVCEADYQPVARAVRERVA 185 
CDQ89056        7 LALRIWVEDpkklkgKHKDNEAIEFSYDLENDSAEEVALEMVKSGFFHESDAKVVGKSIRDRVT 70  
EKC27052      443 VALRLRVVDpkkrrdKHKENEAIQFEFDLDNDQAEDVALEMVKSGYLVEEDVKTVTRQIKERTQ 506 
2LRU_A         26 IKLWLRIEDikklkgKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVS 89  
XP_022538270  317 IGLRLWVEDqkklkgKYKDSGAIEFTFDLEKEAPDTVAQEMVDSGLFLECDVKLVSKSIRDRVA 380  Mexican tetra
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