7KSO


Conserved Protein Domain Family
EZH2_WD-Binding
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pfam11616: EZH2_WD-Binding 
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WD repeat binding protein EZH2
This family of proteins represents Enhancer of zest homolog 2, (EZH2) a 30 residue peptide which binds to a WD-repeat domain of EED by residues 39-68. EED is a component of PRC2 complex which is involved in gene expression. This interaction is required for the HMTase activity of PCR2.
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Statistics
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PSSM-Id: 463308
Aligned: 10 rows
Threshold Bit Score: 53.2231
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
7KSO_A        39 KALYVANFAKVQEKTQILNEEWKKLRVQPV 68 
XP_014342734  54 KSLFTANRNKVKERTEVLNEDWKKLRVQPT 83 
CAF90425      36 KSMFSTNRQKIMERTDILNQEWKTRRIQPV 65 
XP_015217358 146 QSQFMANRSKIKEKTELLNDEWSNLRIQPI 175
Q29RB7        45 KALFQSNRRKIEVGTELLNEEWSKLRIQSI 74  zebrafish
XP_005796763  61 KSLFMSNRQKIELQTNLLNTEWSKLRIQAI 90 
XP_017953284  55 RMFYVENLTKAQERAHLLNEDWKKLRVQPI 84 
XP_021068395  42 KALYVANFAKVQEKTQILNEEWKKLRVQPV 71 
XP_003222404  44 KALFASNYAKVQEKLDILNDDWKNLRVQPI 73 
GCF59166      56 KSMFNSNRQKIQDRTEILNQEWKQRRIQPV 85  Paroedura picta
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