3KJO,4HID


Conserved Protein Domain Family
POT1PC

?
pfam16686: POT1PC 
Click on image for an interactive view with Cn3D
ssDNA-binding domain of telomere protection protein
POT1PC is the ssDNA-binding domain on a family of fungal telomere protection protein 1 proteins. POT1PC is able to accommodate heterogeneous ssDNA ligands. Pot1 proteins are the proteins responsible for binding to and protecting the 3' single-stranded DNA (ssDNA) overhang at most eukaryotic telomeres.
Statistics
?
PSSM-Id: 435514
Aligned: 90 rows
Threshold Bit Score: 73.073
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
3KJO_A       153 LCDVQ-PMQYFDLTCQLLGKAE-VDGASFLLKVWDGTRTPF--PSWRVLIQDLVLEGDL---------------SHIHRL 213
EJW82044     189 LNELV-LGGYSDLVVQAISLFI-DDRNSVVLRCWDTTLPSKk-IFMFNDDMITEVICQD---------------EKMEMI 250
EJD74141     199 LNEFF-LGGYNDITVQAIALFI-DDRNNVILRCWDTTSPPRkiFVLNPEFINKVIYRDG---------------KMEMTA 261
EGT59944      23 TYYLQ-WRRYMDLIAQVHSVVL-TQRGTYVLKCWRGTKFGP--ANKAMEVESRLFRVNQdcfkeyivspdpriaNAVEKL 98 
EGT54172      23 NYYLE-WMRYMDLIAQVHSIVL-TQKNMYVLRCWRGDKFGP--RNRALEVESNLFRVTQnyfkqyiappdarigRAVENL 98 
EGT56753      23 TYYLQ-WCRYMDLIAQVHSIVL-TQRDVYVLRCWRGTKFGP--SNRASGVESRLFRVRQeyfkqyiappdprigRAIEKM 98 
2_pfamImport   2 TFYIN-YLRYFDVLGQLHSVAE-TKYGTWMLRLWRATQFGP--EKYERCREEGMFRVRQdyfhryiippdphiaKAINVY 77 
NP_499848     19 RYYKL-FHQYFDLLAQVHSVVE-TMDGLWMLRVWRAQKFGP--ESIKERRERQLFHVTQfsfkryivppnprigKAIEEF 94 
O45595        18 RYYKQ-YHRYFDVLAQVHSVVE-TINGAQMLRVWRGRKFGP--GASAERRERRLFHVTQdsfkryivppnprigKAIEEN 93  Caenorhabditis ...
XP_001639094 354 ISGLDpSTQFVNLACQVLALWKdPALNFLVLQVWDGTTPRY--GCDVEVDDHSRWVMDR---------------KISEQA 416
3KJO_A       214 QN-LTIDILVYDNHVHVARS-LKVGSFLRIYSLHT----K---LQSMnsenqtmlSLEFHLHggtsygrgirvl-----p 279
EJW82044     251 PMdYWCDIVLYEEHANFARNsVKCGDVLLLINTHL--------YHSKs-------GVALVMHnggqsynrsivil----d 311
EJD74141     262 VN-YWCDIVLYEEHGDFARNnVKCGDILLLINIHL--------YHSLn-------GAAFAMHggrrynrsiiil-----d 320
EGT59944      99 GReCLLEIVVYDEHISVLDS-VKSGDFVALQNVHG--------YVNGs------lVHTLTIHggdgmgrnrgitii-pkd 162
EGT54172      99 GKeCLMEIVVYDEHIASLTG-IKSGDFVALKNVHGnvnvR---LPH---------SHTLSMHrgdgdgrnrgisvipndf 165
EGT56753      99 GTeCLMEIVVYDEHVSSLNG-IKSGDFVALKNVHG--------YVNFt------lAHTLTLHrgdgdgrnrgisii-pkd 162
2_pfamImport  78 GYnHLMEIEIYDEHRDYLEA-LRSGEYITVTNVHY----S---KGKVg--------dSLKLHggslynrgifkvp---dd 138
NP_499848     95 GKeYLIEINVYDEHRADLVS-LNSGNFVAIQNVHA--------ASTPh-------REIQILHgggeayqrgistvp--vd 156
O45595        94 GKeLLIEIDVYDDHRDGLKN-LNSGDFVAIQNVHA--------ASTr-------qTEMQVLHgggasyqrgittvp--vd 155 Caenorhabditis ...
XP_001639094 417 GG-MAIPVCLYDEHSTGPAAdLNPGDFVMLANVRL----KevdNEENgk-----pRVECMMHsdcingrgvymlkd--tg 484
3KJO_A       280 esnsdvdqlkkDLESANLT 298
EJW82044     312 ansklkrdllrNIDEFNIQ 330
EJD74141     321 dnnklkldllrNIDEFNAK 339
EGT59944     163 ynqpeflyfkaRIDAVLHS 181
EGT54172     166 rgernlnllreKIKWRLGN 184
EGT56753     163 fnqhefiifkeKINDILAE 181
2_pfamImport 139 csdhrflevkrRIENALDQ 157
NP_499848    157 fevdafqnfkrKVESVLEN 175
O45595       156 feheafqnfkkKVEAVLET 174 Caenorhabditis elegans
XP_001639094 485 wtdwylqklkdSIQNYLDT 503
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap