Conserved Protein Domain Family
KH_9
?
pfam17904: KH_9 (this model, PSSM-Id:407756 is obsolete and has been replaced by 436130)
FMRP KH0 domain
This entry corresponds to the KH0 domain from the FMRP protein. This is a divergent KH domain that was discovered through solving the structure of an N-terminal fragment of the FMRP protein. KH0 does not have the canonical G-X-X-G motif between helices A and B. It has been suggested that this domain may be involved in RNA binding.
Links
?
Statistics
?
PSSM-Id: 407756
Aligned: 5 rows
Threshold Bit Score: 124.527
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
KOF93174     124 KDSFRKAILDVPSDLREVC---------REESTLAEFKKHCGAAVVIYNSDDNALVVV-----ST--------------- 174 Octopus bimacul...
XP_006563725 123 KNTFHKIEIEVPEDLREFA---------KMENAHKEFQKAIGAAVCRYVPERGVLLAI-----SR--------------- 173 honey bee
XP_002403837 132 KSTFTKFELEVPEDLREYQ---------QRLGFCAQLQRNRGDGGLATSDG-SILFLLffwlqAR--------------- 186 black-legged tick
KYO32817     123 KDTFHKIKLEVPEDLRQMC---------AKESAHKDFKKAVGAFSVTYDSENHQLIIL-----SI--------------- 173 American alligator
KPP64538     149 KSTFYRCTVAVPEDLKAACvhslivdgsCSRSARRDFARN--ACSFTSGAKMNSCTKT-----SRkrwrpvgsstamnrg 221 Asian bonytongue

KOF93174     175 -----NFSVIKKASLMGDMFLRNLRQKVLLKQRTEEAVK 208 Octopus bimaculoides
XP_006563725 174 -----HENLHRHSTMLQEMHFRNLSQKVLLLKRTEEAAR 207 honey bee
XP_002403837 187 -----SEAAKKRAEMMSEIYYRNLRQKLILLSKTEEAAR 220 black-legged tick
KYO32817     174 -----NDVTTKRANMLIDMHFRSLRTKLSLILRNEEASK 207 American alligator
KPP64538     222 assywKESTMKRVSILSDMHLRNIRTKLMLMSRNEEATK 260 Asian bonytongue
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap