Conserved Protein Domain Family
CiPC
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pfam15800: CiPC (this model, PSSM-Id:406281 is obsolete and has been replaced by 464879)
Clock interacting protein circadian
CiPC is a family of proteins found in eukaryotes. The protein was identified in sheep as a gene-orthologue involved in regulation of the circadian clock. Proteins in this family are typically between 220 and 400 amino acids in length.
Links
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Statistics
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PSSM-Id: 406281
Aligned: 10 rows
Threshold Bit Score: 339.843
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_007472827  38 SDKDSGFSDGSSECLssaeQMDSEDMLNTLSWHGEDGP-----RQNSTIASNSFPALSPMVVMKNVLVKQ------GRNS 106 gray short-tail...
Q1LVI5        57 SEKDSGYSDTGSDSL----QTDADDRQSSASEPQNHKGs----LHGSHILVSGTPELTPIFIIKDVVLKQ------PGQS 122 zebrafish
NP_001314832  11 TDKD---SDASSGYFsaldQTDIEDIGPTGSAALNMPT-----APRVPFITGSHPGISPMIVMNNFVLKQ------PNST 76  zebrafish
XP_006632440  37 SERDSGFSDASSEYLsaveQTDAEDGQKTSAQSIKSKSq----LPQLAVMGGGYPGLSPMIIMNNVLLKQ------ASNC 106 spotted gar
XP_005449781  29 SERDSGFSDASSEHMstmdTTDSEDSPHPVVQQGPRTTgsgthPPGLAVVGG----LSPMIIMNNVLLKQ------PGEN 98  Nile tilapia
XP_005986588  38 SDKDSGFSDGSSEYLsaaeQTSSEDMPNFPSWILASRA-----QQNTMLVNSPFSALSPMFFMKNVLVKQ------PICD 106 coelacanth
XP_015143204  17 SDKDSGYSDGSSECLsameHTDSEDVLNTLCWNAEDGP-----WPCPVTTSGSFPALSPMVVMKNVLVKQ------GSSS 85  chicken
XP_001508288  38 SDKDSGFSDGSSECLssaeQMDTEDMLNPLGWTGDDGS-----RQKPDVGSSSFPALSPMVVMKNVLVKQ------GSSS 106 platypus
XP_003260842  38 SDKDSGFSDGSSECLssaeQMESEDMLSALGWSREDRP-----RQNSKTAKNAFPTLSPMVVMKNVLVKQ------GSSS 106 northern white-...
XP_005991653  55 CESDSGFSDTSSEHLsnaeQADLPDI--KIDWSSVSSR-----LDELQRVYGPFTGLTPVYIVKNVLFKQwnqanaGLDM 127 coelacanth

XP_007472827 107 ------SHLQ-------------------SWTVQPSFEVISt---QPQLVFLHPSV--PPPVSPYP-------AGEKKND 149 gray short-tail...
Q1LVI5       123 gqdhilPSSL-------------------SWGGGTAGGQAP----THVLLLQQPGInqSTPLHILKshpqrseSKNAKKS 179 zebrafish
NP_001314832  77 a-----PALK-------------------PWSLNTSLDVVP----QSQLLYLQPVAkcLPSGDSTSq------SFDKQKH 122 zebrafish
XP_006632440 107 p-----PAVK-------------------PWGFQPAIEVIP----QPQVVFLQPVI--SNGITNTQk-----gPQDKRRR 151 spotted gar
XP_005449781  99 p-----PALK-------------------PWGFSPTVEVVQpvvqQPQVVFIQPVV--SRQASSGTk-----eANSKHRR 147 Nile tilapia
XP_005986588 107 ------QLVQ-------------------SWAVQPSIEVIPa---QPQLLLVQPAV--PQTINSRS-------TRDNKAD 149 coelacanth
XP_015143204  86 -------QLQ-------------------SWTVQPSFEVIPa---QPQLVFLHPSI--PPPINPHP-------VGKKRND 127 chicken
XP_001508288 107 ------SELQ-------------------SWTVQPSFEVISa---QPQLVFLHPSV--PPPVSPFH-------AGEKKSD 149 platypus
XP_003260842 107 ------SQLQ-------------------SWTVQPSFEVISa---QPQLLFLHPPV--PSPVSPCH-------TGEKKSD 149 northern white-...
XP_005991653 128 ------EYLPqsllpftvqtnnqilhtqlAWGGQHALSAASg---QPRVLFIQQPV--AASTLKSP-------VSNKRKE 189 coelacanth

XP_007472827 150 SRNYLPILNSYTKIAPHPGK-----------R---------------GLALNPEERGET---SMQKRVCTERHRTSLSST 200 gray short-tail...
Q1LVI5       180 KNTYLPILNSYPRIAPHPSK-----------Ka--------------TEKPTTNRGSNTeehSLSKRVCTEEKREKVSTT 234 zebrafish
NP_001314832 123 SKKHAPLQSTFQKIAPHPAQ-----------Ept------------vDQGPGAINRRSSh--SHAGRHHRHRYEDKPFHN 177 zebrafish
XP_006632440 152 SQKYLPILKSYPKIAPHPGE-----------Sss------------eRSASGSSERSGSa-sARVDRASALRHRRHSREK 207 spotted gar
XP_005449781 148 PKKYLPILKSYPKIAPHPGD-----------SssssgrgtapstyssS-SSSGSEKCSTl--TSITREHCQREKPQ--RS 211 Nile tilapia
XP_005986588 150 SGSYLPILKSYAKIAPHPGK-----------Kltp---------gkdAISPRDGRRGLSdshKKQKRVETSRTSSAFRSS 209 coelacanth
XP_015143204 128 STNYLPILNSYPKIAPQPCK-----------Rd---------------HSFDLEERQET---SCHKRLCTEASKMENSPV 178 chicken
XP_001508288 150 SRNYLPILNSYTKIAPHPVK-----------R---------------SLSLTLEERGEA---SDRKRTCTDRHRTSLSSL 200 platypus
XP_003260842 150 SRNYLPILNSYTKIAPHPGK-----------R---------------GLSLGPEEKGTS---GVQKKICTERLGPSLSSN 200 northern white-...
XP_005991653 190 RDTYLPILNSYPKIAPHPDKsrdnqangqtsE---------------NHGILRTDRTAGr--SKNKRFCVEDTRVSSSES 252 coelacanth

XP_007472827 201 ------------------GPTKTs----------ILPSDPSTPVPPSTKlaq--------dsvRQSLSSLVASRSLR--- 241 gray short-tail...
Q1LVI5       235 ------------------TQASKqhphk-qpennLLSNSHSLSRSLSAG--------------HETSTDTHKNRSPCrps 281 zebrafish
NP_001314832 178 fplkqdvsetfsgygvdpSISSLeeigh-tvedmHVKDSPSR------------------------------LSDFQeph 226 zebrafish
XP_006632440 208 ------------------QLSRLsstasptpsglPLPLTPEPSTRKHHSsls--------kteSASSGGQPTPPASSqea 261 spotted gar
XP_005449781 212 ------------------LCNSAgnsgp---ttpslPATPTTMSPLLQSrlc--------lstGETNT----TPARErps 258 Nile tilapia
XP_005986588 210 ------------------SAAQP-----------FSPQSSGTNKQQNSEilp--------snrTQTNSELACNGHTGrqe 252 coelacanth
XP_015143204 179 ------------------SRST------------VLSTSPFAHIPVSFKapq--------dsnQQSSSSLMTTGKVS--- 217 chicken
XP_001508288 201 ------------------GPTKTd----------VSPSSPSA-VPPDLRlaq--------dsaRQSSSSSLAGGALR--- 240 platypus
XP_003260842 201 ------------------EPTKAg----------AVPSSPSTPAPPSAKlae--------dsaLQGVPSLVAGGSPQ--- 241 northern white-...
XP_005991653 253 ------------------AMPKNnevpsaaperqEQPSPPTASIQQASNaafkldrfvqsegyRACSSPHLGVPLSQspa 314 coelacanth

XP_007472827 242 ------TVPDSQEVLSSTMAKAPNLTFASPASPLGSSDSTLHGLESPMPLSMLSapysppgagdql-chspetfleqrQS 314 gray short-tail...
Q1LVI5       282 spsaslSVSSPSVSSTQIPSPPSSVDLIQTRKEPHKHCPGQKSDSGKGSHTFKG------------------------TA 337 zebrafish
NP_001314832 227 tttspfSLCTDSFLAA--------FPQKFPKTSISQSSDVESIPEALSPSSS---------------------------- 270 zebrafish
XP_006632440 262 ----------------ppPARSPGLAPVPPAAASPSRTDPDPDPEEKGSVLEK-------------------------RN 300 spotted gar
XP_005449781 259 savsqaDCTTLLSFSHATGSKNRTLSVSPAVVSLSEGND------SDGDADT---------------------------- 304 Nile tilapia
XP_005986588 253 edcftpTLESGHLQLSANAASDEALFLCPSPSVGQIASAQELGPAAATSGQMAQq-----------------------QS 309 coelacanth
XP_015143204 218 ------TLPGFHCV-SADTPKVPGLASLLPFGALQTAKCTPHENESAAQTTMQSavwslplipee--tcttpelllqqQS 288 chicken
XP_001508288 241 ------TVHSIQLGPSGRLVKGPRLTPEVPPSPPFTVDGSGRGAENTVSPSTPAapssppatvgql-rrtleafpeprQS 313 platypus
XP_003260842 242 ------TL---QPVSSSHVAKAPSLTFASPASPVCASDSTLHGLESNSPLSPLSanyssplwaaehlcrspdifseqrQS 312 northern white-...
XP_005991653 315 fssaelSPSSAALE----------FPVGMLPSGTGDRKGANKGSKKHAPGIV---------------------------- 356 coelacanth

XP_007472827 315 KHRRFRNTLVILHRSGLLEITLKTKELIRQNQATQIELDRLKEQTQLLMEATKGNA--PQAWAKLQ 378 gray short-tailed opossum
Q1LVI5       338 RHRRFLNTVEILSQSGLLDITLRTQDLLRQNAATDRDIAQLRQHAQLLFQAAQAGVdaPAAWEKLQ 403 zebrafish
NP_001314832 271 KRKRFCNTYNILNRSGLLGITMRTKELIRQNKRSQAQLQSLQAQTDLFLEAICSRD--PKVWTRLQ 334 zebrafish
XP_006632440 301 KRKRFCNTYNILHKSGLLGITLRTKELIRQNRKTQSELDRLKAHADLFVEAIRSGD--PQVWTKLQ 364 spotted gar
XP_005449781 305 RRKRFCNTYNILSKSGLLDITLRTKELLKQNQRTQNDIDRLKKQTDLFLQALRSGD--TRICVKLQ 368 Nile tilapia
XP_005986588 310 KQKRFQNTFDVLHKSGLLGITLKTKELARQNQSTQNELDQLKEQTRLFVEVLQSNN--PLVLAQLl 373 coelacanth
XP_015143204 289 KCRRFQNTLVVLRRSGLLEITLKTKELIHQNQVTQAELDRLKHQTQLFIEAIKNNA--PQSWAELE 352 chicken
XP_001508288 314 KHRRFQNTLVVLHRSGLLEITLKTKELIRQNQATQVELDRLKEQTQLLVEAAQSNA--PQAWAKLQ 377 platypus
XP_003260842 313 KHRRFQNTLVVLHKSGLLEITLKTKELIRQNQATQVELDQLKEQTQLFIEATKSRA--PQAWAKLQ 376 northern white-cheeked gibbon
XP_005991653 357 KQKRFHNTVEILSKSGLLGITLKTKGLIRQNRNTQREIDELKEHTRLLCKAMQSND--SQAWLKLQ 420 coelacanth
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