Conserved Protein Domain Family
DUF4685
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pfam15737: DUF4685 (this model, PSSM-Id:406224 is obsolete and has been replaced by 464834)
Domain of unknown function (DUF4685)
This domain family is found in eukaryotes, and is typically between 106 and 131 amino acids in length. There are two conserved sequence motifs: SGE and VRF.
Links
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Statistics
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PSSM-Id: 406224
Aligned: 18 rows
Threshold Bit Score: 116.001
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Download Cn3D
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_021578272  353 RTFGPKPEPMLSARHEEAKHLLHRARMKARTQPLRANHDIVPTIAQGS-R-DGQ----RGPAPDPRMTLACRDSlqn--g 424  thirteen-line...
XP_007664167   19 RACVPSQELVLSPQSEQAKQLLQRGRMKARTGPLRASHDILPASVPHQ-R-FAG----GDPAPEPRMTSAPRDGdgshgg 92   platypus
EHA99933       71 CQFLPDLQDQLSGFQERLEKILHQ--RTSSLGQLSGDHSQFPTVRKAS-----S----FCGTPAPEAM------------ 127  naked mole-rat
XP_014972129  176 CSFLPDLWGQSSHLQDSLTKILLH--QTPTLGSLKGHHSQFTTVKKAN-H-RPH----GAQVPKLKAA------------ 235  Rhesus monkey
XP_002691719  198 SHFLPELGGQSSYLKNSLKKILLH--QIPALGPLSRDYPQFTTVKANQ----PQ----ATQAPKLKAV------------ 255  cattle
XP_023357582  331 RAFVPSQELLLSPRNEQAQRLLQQARMKARTSPLRASHDIVPAVAVRLpGrDAG----CGVGQNPRLTLASQDGdapygg 406  Tasmanian devil
XP_007480966  322 RALVSSQQLSLSPRHEQANQLLQQARMKAKTSPLRANHDIVPSMAH---R-LPArdvsSGTIQTPRVTLACREGdvpysg 397  gray short-ta...
XP_008697107  105 CSFLPDLRGQSSYFQNSLKKILLH--QIPTLGTLRRDHSQF-TLKKAN-H-RPH----GAQAPKLKAV------------ 163  polar bear
XP_009002416   49 RSFLPDLWGQSPHLQDSLTKILLQ--QTPALGSLKADRPQFSTVRK---------------------------------- 92   white-tufted-...
XP_014341089  362 RAFVSSEEPTLSPRHEQAKRLLERARMKARSSPLKADHSILPLKKDCCpR-QSH----GSGVHA---VKKTRNEspplsg 433  coelacanth

XP_021578272  425 nVSDSSSGEsssGQWPKQGTSPSHVRFQDETAREAESRYLERLQQRQRQVLST 477  thirteen-lined ground squirrel
XP_007664167   93 nLSDSSSGEsgcGQPRKRGLSPSRVRFEDESTRDAEVRYLDRMQQRQRRMLDS 145  platypus
EHA99933      128 -PTPTPSGE---GLGPRRHSCPFQVRLADEMLTDSALCYWEHSCAVQQSRMSp 176  naked mole-rat
XP_014972129  236 -LTHNPSGE---GSKPRKRRCPFRVRFADETLQDTTLRYWERRCSVQQSVIVN 284  Rhesus monkey
XP_002691719  256 -LTHNSSGE---GSGHRRRCCPFRVRFADETLRDTALRYWERSCAARQGIFEN 304  cattle
XP_023357582  407 sLSDSSSGEsscGQRRKRGPSPSRVRFEDESAQDAEVRYRERSQQPPRRALDS 459  Tasmanian devil
XP_007480966  398 sLSDSSSGDsinDQRRKRGLSPSRVRFEDESAQDAEVRYRERLQQPQKRALDS 450  gray short-tailed opossum
XP_008697107  164 -LTHSSSGE---SSGQRRRGCPFRVRFADETLRDTALRYWERSCAVRQGTIEN 212  polar bear
XP_009002416   93 -ASHRPSGK---GSGPHRPRCPFRVRFADETLQDTLLRYWERQCSVTQSVTVN 141  white-tufted-ear marmoset
XP_014341089  434 nLSDSSSGEsncGLQKKRGQSPTRVRFEDESARDAEVRYWEREQQRKKGTLDl 486  coelacanth
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