Conserved Protein Domain Family
DUF4587
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pfam15248: DUF4587 (this model, PSSM-Id:405845 is obsolete and has been replaced by 464588)
Domain of unknown function (DUF4587)
This protein family is a domain of unknown function. The precise function of this protein domain remains to be elucidated. This domain family is found in eukaryotes, and is typically between 64 and 79 amino acids in length. There are two conserved sequence motifs: QNAQ and HHH. In humans, it is found in the position, chromosome 21 open reading frame 58.
Links
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Statistics
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PSSM-Id: 405845
Aligned: 24 rows
Threshold Bit Score: 65.8755
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Download Cn3D
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_006636780 149 KSGSIKEDMVELMLMQNAQMHQIIMHNMMLKAIPPMAFSPTGggrhpgpapnQQFsqPNQDSYLGSPIILKSE---KPRG 225 spotted gar
EDL97148     142 RSGSIKEDMVEMMLMQNAQMHQILMQNMMLKALPPGpt------------gpRAT--TLQDQRWVHHGVPRAE---KQKP 204 Norway rat
EHB07343      39 QPGRVKEDLLELMSLQNAQMHQLLLSRLVARALNPETDSPGV----------QVYleGQQEEP-------EEEvhiQEEV 101 naked mole-rat
ELK12465      35 QPSRVKEDLLELMMLQTAQMHQLLLSRLVAAALNLQPASPLP----------QVCpeGQQEERG-----EEEEleaPEEG 99  black flying fox
XP_011229722  41 RPGRVKEDLLELMLLQNAQMHQLLLSGLAAGALNPSLGSCHP----------QVYleGQQEEEEEEEVGEEEEmqaQEEG 110 giant panda
EGV99166     100 RS---PYDLLELMMLQNAQTHQLLLGQLVAGALSPGPEWPHP----------QVYtdSQQEQVE-----EEMEtqeQEQE 161 Chinese hamster
XP_005257862  39 QPGRVKEDLLELMMLQNAQMHQLLLSRLVAGALQPRPASPCP----------QVYleVPQEEPEE----EEEEmdvREKG 104 human
8_pfamImport   1 RKEQIREDLMELMMIQNAQMYQVIMNNIAISAVEHFGPNPVQ----------DISlkLPQKSPMEMQIEDNEE---SDPA 67 
XP_015217363  52 QPGHVKEDLVELMMIQNAQMHQVIMNNMTMSALNAFGYSQST----------------PQPPPEPPRYPIIVE---EEYP 112 spotted gar
XP_027830146  39 QPGRVKEDLLELMMLQNVQMNQLFLSGQVAAVLNQGLSWTNS-----------------QVSLE---IQQQEEkepQEEG 98  sheep

XP_006636780 226 SSVHHHHHY 234 spotted gar
EDL97148     205 SPVHHHHHY 213 Norway rat
EHB07343     102 PLVFHHH-Y 109 naked mole-rat
ELK12465     100 PLVLHHH-Y 107 black flying fox
XP_011229722 111 PLVFHHH-Y 118 giant panda
EGV99166     162 PVVFHHH-Y 169 Chinese hamster
XP_005257862 105 PLVFHHH-Y 112 human
8_pfamImport  68 PRIFHHH-Y 75 
XP_015217363 113 EPVYHHHYE 121 spotted gar
XP_027830146  99 PLVFHHH-Y 106 sheep
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