Q8NAN2        60 YYSLSQIKFSP-VAKKLFVVTAVSA---ISVIFLAHHFKRKRGKKKGk---iLPWEPEHLILEYTKRA----------AS 122 human
XP_003451554  32 QSIFSQLRLTP-SLKKVLFATALGS---VALALTAHQLKRRGRKRKQgtqekDGQKTVGIPESLMKTGrpssl-krapFT 106 Nile tilapia
Q5BLE2        32 QSIFSQLKLSP-SLKKVLFATALGS---VALALTAHQLKRRGRKRKQtl-gkEAQKPVGIPEQLLRSSrpasl-krgpVP 105 zebrafish
Q8BK03        32 QSAFSQLRLTP-GLRKVLFATALGT---VALALAAHQLKRRRRKKKQvgpemGGEQLGTVPMPILMARkvps--vkkgCS 105 house mouse
EOB05910      32 QSVFSQLRLSP-GLRKVLFATALGT---VALALAAHQLKRRRRRKKQiapdkCGFKPGGITVPILPTRrvss--vkkgYS 105 mallard
CAP39560       7 QGLPVGLKINDiVTKRTVLSVAAGIgigIVFANFVRYWKQRRESRIP-----LSAFIDEVPKEVDTNPsqpapslrrsHS 81  Caenorhabditis ...
EDW51314      12 gGSLLPFRVST-TTKVVLFSLTAGV---ALMSVLSRFLRRRKPPRPPrra--------------------------rkYT 61  Drosophila sech...
XP_001847702   3 VSRLLPFNLTT-SQKVIVVSVTAGM---AVLGVIASYLGRRRTPKPQqrr-------------------------lrkPG 53  southern house ...
XP_017952118  32 QSTFSQLRLSP-GLRKVLFATALGT---VALALAAHQLKRRKHKKKQitadkGGLKLGGVPSSVLPVRrsss--akkgYS 105 tropical clawed...
XP_014341668  32 QSIFSQLRLSP-SLKKVLFATALGS---VALALTAHHLKRRRRRRKQiaeekDAQKPRDVAGHLLPAArptp---vkkGS 104 coelacanth

Q8NAN2       123 DKGSSCSSSRQNLTLSLSStkDKGSQVCNyangglfsKYSGSAQSLASVQ-SVNSCHSCACGN-SNSWDKADE--DDIKL 198 human
XP_003451554 107 GRQMMSPSTRSNDTMSGIS--SLAPS-----------KHSSSSHSLASTR-VPSSPNQSANP--STPWEAEPVveESGAV 170 Nile tilapia
Q5BLE2       106 ARQMMSPSTRSNDTLSGVS--SIAQS-----------KHSSSSHSIASMR-VPSSPNQSVNA--GAAWEAEPVaeEPAVG 169 zebrafish
Q8BK03       106 SRRVQSPSSKSNDTLSGIS--SIEPS-----------KHSGSSHSLASMV-VVNSSSPTAAC--SGSWEARGMe-ESVPT 168 house mouse
EOB05910     106 SKRVQSPGSKSNDTLSGIS--SIEPS-----------KHSSSSHSLASMV-AVNSSSPTPAA--AGTWEAQAMg-DAGAG 168 mallard
CAP39560      82 GRGMRPSSSQGERSLRNSV-------------------RQNSQRSLS--------------------------------- 109 Caenorhabditis ...
EDW51314      62 GRRNRNSMRSPNDLISIAG--SKASARSG--------SPVGSTLAYSDRL-SMASGSIGVGVLgVQNAGPGSSv------ 124 Drosophila sech...
XP_001847702  54 GRKTRNSVRSPNDIISLAG--SKASGRSY--------SPGGSIHGLSDRM-SLASGSLAAAGAg--------------PI 108 southern house ...
XP_017952118 106 RSRVQSPSSKSNDTLSGIS--SLEPS-----------KHSSSSHSLTSVV-AVNSSSVNVAS--AGPWESPEMd-ETLEE 168 tropical clawed...
XP_014341668 105 SKRVQSPSCRSNDTLSGIS--SIAPS-----------KHSSSSHSLASVSkSSAARGSXPFX--TLGRINNFPk-----C 164 coelacanth

Q8NAN2       199 VNIPVTTPENLYLM-GMEL---FEEALRRWEQALTFRNRQA---EDEA-CGSIKLGAGDAIAEENVDDIISTEFIHKLEA 270 human
XP_003451554 171 ED---ANAENLYLM-GMEL---FEEALRKWEQALNIRHQPH----STSsNNSLALQGATCGDVTT-GEAQNKVFAEKLET 238 Nile tilapia
Q5BLE2       170 ED---ANAENLYLM-GMEL---FEEALRKWELALNIRHRSH---SRASaSNS---QGSELVERHS-PEVRNHQFAERLET 235 zebrafish
Q8BK03       169 TD---GSAESLYVQ-GMEL---FEEALQKWEQALSVGQRGDg-gSTPTpGDSLQNPDTASEALSE-PESQRREFAEKLES 239 house mouse
EOB05910     169 GD---SSAESLYVQ-GMEL---FEEALQKWEQALTIRQRDSastSTPVpWDGKKHQDTLSESIAE-EESQKREFAEKLES 240 mallard
CAP39560     110 -----MNPIEADITnGQEMctdLRKTIERVHHNLEMVKNRS---------------------------SKDMERSIKIEG 157 Caenorhabditis ...
EDW51314     125 --VTQLTAQQLGMM-GMEA---LDTVINFWEDALAAHYSPG-------------------GLPALLTTAEDSEFCREIQN 179 Drosophila sech...
XP_001847702 109 GGTTPLTPQQLGVM-GMEA---LETVISYWEDALTGRNDID--------------------IPSRLS-ADQEEFCRELQN 163 southern house ...
XP_017952118 169 ED---SNAENLYIQ-GMEL---FEEALHKWEQALNLGQRSRs--NTPLsQVNEPLNKSYSEGLSE--DSQSRQFAGRLEA 237 tropical clawed...
XP_014341668 165 GG---AF-ISLGFA-GMEL---FEEALLKWEQALNIRQHRG---SDMGaKMKVIQPGASGDSVSE-QEFRNKDFAQKLEG 232 coelacanth

Q8NAN2       271 LLQRAYRLQEEFEATLGAsDPNSLADDI--DKDTDITMKGNvEDFG------LRDTLSIAST-----------------D 325 human
XP_003451554 239 LLHRAYHLQEDFGSSI---PADNVLADFesEGTLILPQVESfHRLQ------EDDATTVTSD-----------------D 292 Nile tilapia
Q5BLE2       236 LLHRAYHLQEDFGSTI---PPDSLLADLesEGTLILPTLGSsHPIQ------DDDATTVTSD-----------------D 289 zebrafish
Q8BK03       240 LLHRAYHLQEEFGSTF---PSDSMLLDL--ERTLMLPLTEGsLRLR------ADDEDSLTSE-----------------D 291 house mouse
EOB05910     241 LLHRAYHLQEEFGSSL---PSDSMLLDL--EKTLMLPLADGsLRLR------TDDEDSSISE-----------------D 292 mallard
CAP39560     158 ILKGLKQVEDEITMLIPHmEDFR-------DDNTEFYSVSGgTGYAgsvrtgRSRTLSVLSD-----------------D 213 Caenorhabditis ...
EDW51314     180 LLEMAYTLQEQSELLFLD------------QRSVLFREEHSiDEVEeeageaDDDRRSHKSGsvlsrags--dpnfdsaE 245 Drosophila sech...
XP_001847702 164 LLDAAYNLQENGELLFLD------------ERSVLYR---------------DDENKATQAAslsnghrsssdpnmdsaE 216 southern house ...
XP_017952118 238 LLHRAYNLQEEFGTSI---PPDSLLMDL--EGSLMFPLAESrRALL------TYEEGSTTSE-----------------D 289 tropical clawed...
XP_014341668 233 LLHRAYHLQEEFGVAL---PPESLMLDFenEGTLALPLSGSsERLY------LDDEASVTSE-----------------D 286 coelacanth

Q8NAN2       326 SFASAAE--LAE-HREVRHTYSLESLCHCP-----FYEEAMHLVEE-------GKIYSRVLRTEMLECLGDSDFLAKLHC 390 human
XP_003451554 293 SFFSAAE--LLD-------AMSLGEVcqp----aaLYEEALSLVHE-------DKVAYRTLRTELLECYSDQDFLAKLHC 352 Nile tilapia
Q5BLE2       290 SFFSAAE--LFE-------TFSLEDS-FHLlkpaaLYEEALSLVKD-------GDVACRSLRTELLECYSDQDFLAKLHC 352 zebrafish
Q8BK03       292 SFFSATE--IFE-------SLQIGEYPLPLsrpaaAYEEALQLVKE-------GRVPCRTLRTELLGCYSDQDFLAKLHC 355 house mouse
EOB05910     293 SFFSAAE--LFD-------SLHFEEIPFHLskpvaAYEEALQLVKE-------GKVACRTLRTELLGCYSDQDFLAKLHC 356 mallard
CAP39560     214 SFQSAVEefAVDiDDIDFVSEAAN-----------LEKEELKFLDEgmraamnGEVKYRKSRMDFCNCESETDFAAKLYC 282 Caenorhabditis ...
EDW51314     246 SFASALDq-VADlREFDGFIET--SYEEYP-----LFQSALKHHDE-------YTVPCRTIRAELMHCSTDTEYLAKLHC 310 Drosophila sech...
XP_001847702 217 SFASALDqvQSDlREFEDYGEVFSDVENYP-----LYQSALELLDD-------QPIPCRTIRTDMVGCNSDAEYYAKLHC 284 southern house ...
XP_017952118 290 SFFSAAE--LFD-------TLQLNEVPFRPpkpaaAYEEALMLVHT-------GEVACRTLRTELLGCYNDQDFLAKLHC 353 tropical clawed...
XP_014341668 287 SFFSAAE--LFE-------SLQFSGDSFQPakpaaLYEEALGLVRD-------RKVDCRTLRTEVLGCYNDQDFLAKLHC 350 coelacanth

Q8NAN2       391 IRQAFQVILSESANRIFLAESGRKILSALIVKARKNPKKFEDVFDEMIYFLEQTDHWGSTEMELAARGVKNLNFYDVVLD 470 human
XP_003451554 353 VRQAFQILLLDETHRTFFMETGKQMIVGLMVKANKSPKAFLESYEDMLLYTQREETWPITKMELEGRGVVCMNFFDIVLD 432 Nile tilapia
Q5BLE2       353 VRQAFQVLLLDETHRMFFMETGKQMISGLLVKANKSPKAFLESYEDMLQYTQREETWPVSKMELEGRGVVCMNFFDIVLD 432 zebrafish
Q8BK03       356 VRQAFEGLLEERSNQIFFGEVGRQMVTGLMTKAEKSPKGFLESYEEMLSYALRPETWATTRLELEGRGVACMSFFDIVLD 435 house mouse
EOB05910     357 VRQAFQELLEDESNQLFFGEVGKQMVIGLMTKAEKNPKAFLESYEEMLHYALKPETWPTTQQELEGRGVVCMSFFDIVLD 436 mallard
CAP39560     283 VRHALTNALKDEHKRVWLAKCGRTLLADFIRHTKQDPVKFFNAYDEMLEYVSNDRNQEQLRQDVEGRGVCETGFYDVAVD 362 Caenorhabditis ...
EDW51314     311 VRLAFQFLFKDPAVGQWICDAGRQILTDLLCLGDKDTKEFLVGYEDMVNYLHDSNNWPCIQMELEQRNVKAMTFYDICLD 390 Drosophila sech...
XP_001847702 285 IRLAFQLLFKDPKISRWVADTGRQVLTDLLCLGDKDPKDFLVSYESMLEFLQNQDNWPDIEAELESRQVKAITFYDIVLD 364 southern house ...
XP_017952118 354 VRQAFEVLLLDERNRLFFGEVGKQMVSGLMQKAEKNPKGFLENYEEMLRYALKEDTWTTTQKELKGRGVVCMNFFDIALD 433 tropical clawed...
XP_014341668 351 VRQAFQVLLEDESQRLFFSEIGKEMITGLMTKAGKSPKGFLESYQEMLRYTVKEETWPTTQRELEGRGVVCMNFFDIILD 430 coelacanth

Q8NAN2       471 FILMDSFEDLENPPTSIQNVVNNRWLNSSFKETAVASSCWSVLKQKRQQMKIPDGFFAHFYAICEHISPVLAWGFLGPRN 550 human
XP_003451554 433 FILMDAFEDLESPPSSVVAVLRNRWLSDSFKETALATACWSVLKAKRRLLMVPDGFISHFYAISEHVSPVLAFGFLGPRQ 512 Nile tilapia
Q5BLE2       433 FILMDAFEDLESPPSSVVAVLRNRWLSDSFKETALATACWSVLKAKRRLLMVPDGFIAHFYVISEHVSPVLAFGFLGPHQ 512 zebrafish
Q8BK03       436 FILMDAFEDLENPPSSVLAVLRNRWLSDSFKETALATACWSVLKAKRRLLMVPDGFISHFYSVSEHVSPVLAFGFLGPKP 515 house mouse
EOB05910     437 FILMDAFEDLENPPSSVLAVLRNRWLSDSFKETALATACWSVLKAKRRLLMVPDGFISHFYSVSEHVSPVLAFGFLGPKQ 516 mallard
CAP39560     363 FIILDAFEDLKSPPSAVYSVTKNYFMSMSMKYSTLNTIIWSIIKSKRQRLKNPDGFIAKFYNISETVMPAITLGFLGTDE 442 Caenorhabditis ...
EDW51314     391 FIILDSFKDLDAPPASVTAVVQNRWLSNGFKETALTTAVWSVLKAKKRMLKFPNGFMSHFYVISEQISPLMAWGFFGPNE 470 Drosophila sech...
XP_001847702 365 FIILDAFRDLDTPPNSVLAVINNRFLSNSFKETALTTAVWSVLKAKKRLLKFPNGFMSHFYCVTEQLSPLMVWGFFGPDE 444 southern house ...
XP_017952118 434 FILMDAFEDLESPPSSVIAVLRNRWLSDSFKETALATACWSVLKAKRRLLMVPDGFISHFYSVSEHVSPVLAFGFLGPKE 513 tropical clawed...
XP_014341668 431 FILMDAFDDLESPPSSVVAVLRNRWLSDSFKETALATACWSVLKAKRRLLLVPDGFISHFYSISEHVSPVLAFGFLGPKP 510 coelacanth

Q8NAN2       551 SLYDLCCFFKNQVLLFLKDIFDFEKVRYSSTETLAEDLMQLLIRRTELLMAYL 603 human
XP_003451554 513 HLSEVCTIFKQQIVQYLKDMFDHDKVRFTSAQCLAEDILNLSHRRSDILLGYL 565 Nile tilapia
Q5BLE2       513 HLSEVCTIFKQQIVQYLKDMFDHDKVRFTSVPSLAEDILRLSHRRADILMGYL 565 zebrafish
Q8BK03       516 QLSEVCAFFKHQIVQYLRDMFDLDNVRYTSVPALAEDILQLSRRRSEILLGYL 568 house mouse
EOB05910     517 QLSEVCGFFKHQIVQYLKDMFDFDNVRYTTVQLLAEDILQLSRRRSEILLGYL 569 mallard
CAP39560     443 RLGELCQYFKEQVVQFVLDVFNTQRVCYRSLEEMTEDVWIVMRNRLEAVQTRM 495 Caenorhabditis briggsae
EDW51314     471 NLRDICHYFREELLAFLGDIFSFQKSRFTTIEEFSQDVLQHMQTRVNNIGVKF 523 Drosophila sechellia
XP_001847702 445 DLKEVCKYFKDQMVGFMIDMYNFQKMRYTTVEELAEDIHTNMRMRVNNIGVKF 497 southern house mosquito
XP_017952118 514 HLAEICNFFKHQIVQYLTDMFDLDKVSYTTIQSLADDILHLSRRRSDILLGYL 566 tropical clawed frog
XP_014341668 511 QLCEICTFFKQQIVQYLKDVYDLDQVRYTTVQSLADDILQLSQRRSEILLGYL 563 coelacanth