pfam10215: Ost4 (this model, PSSM-Id:402012 is obsolete and has been replaced by 431142)
Oligosaccaryltransferase
Ost4 is a very short, approximately 30 residues, enzyme found from fungi to vertebrates. It is a member of the ER oligosaccaryltansferase complex, EC 2.4.1.119, that catalyzes the asparagine-linked glycosylation of proteins. It appears to be an integral membrane protein that mediates the en bloc transfer of a preassembled high-mannose oligosaccharide onto asparagine residues of nascent polypeptides as they enter the lumen of the rough endoplasmic reticulum (RER).
Jiyao W et al.(2023). "The conserved domain database in 2023.",