4J2X


Conserved Protein Domain Family
LAG1-DNAbind
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pfam09271: LAG1-DNAbind (this model, PSSM-Id:401274 is obsolete and has been replaced by 462735)
LAG1, DNA binding
Members of this family are found in various eukaryotic hypothetical proteins and in the DNA-binding protein LAG-1. They adopt a beta sandwich structure, with nine strands in two beta-sheets, in a Greek-key topology, and allow for DNA binding. This domain is also known as RHR-N (Rel-homology region) as it related to Rel domain proteins.
Links
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Statistics
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PSSM-Id: 401274
Aligned: 50 rows
Threshold Bit Score: 98.8769
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4J2X_A         27 VLILHAKVAQKSYGNEKRFFCPPPCVYLMGSgwkkk-------------------------------------------- 62  
Q5KPQ7        116 LEVWHPTTGQKSYGKERRMLNPPPILRLSGP------------------------------------------------- 146  Cryptococcus ...
XP_006956985  177 ISISTPQTAQKSYGNEKRFIAPPPQVCLIGKnwnsenkkggqshalaldlgqlspsvqvklgnglqahdcelkwsqftes 256  Wallemia mell...
O74412        473 FYLCMPSLCQKSYGTERRYLCPPIVLYLLGTtwlnnvtdnlkisaqtl-------------------------------- 520  Schizosacchar...
XP_018229012  379 VMIYTSKVAQKSYGTEKRYLCPPPYLRLLGAkwfesylqdv--------------------------------------- 419  Pneumocystis ...
XP_011392222  379 IRCSHASVAQKSYGSEKRFFNPPPIISITGPlrryaehg----------------------------------------- 417  Ustilago mayd...
CCF51629      368 IRCAHASVAQKSYGSEKRFFNPPPIISVTGPlrryaehg----------------------------------------- 406  Ustilago hordei
GAC72297      358 VRCAHASVAQKSYGSEKRFFNPPPIISVTGPlrryaehg----------------------------------------- 396  Moesziomyces ...
GAC98902      369 IRCSHASVAQKSYGSEKRFFNPPPIISVTGPlrryaehg----------------------------------------- 407  Pseudozyma hu...
CBQ70904      370 IRCAHASVAQKSYGSEKRFFNPPPIISVTGPlrryaehg----------------------------------------- 408  Sporisorium r...

4J2X_A         63 -------------keqmeTDGCSEQESQPCAFIG-IGn-SDQEMQQLNLe-----------------------------g 98  
Q5KPQ7        147 -------------------------ASSCISSITmVSvvSPNITQPVAI------------------------------- 170  Cryptococcus ...
XP_006956985  257 qskqsnlpltppdsspnsNKSDYVEESNDTNQMTmLGk------------------------------------------ 294  Wallemia mell...
O74412        521 --edkdnpkfaknifyynADGALISPETDIAKSTyQLtnYNENTNFDSFp-----------------------------v 569  Schizosacchar...
XP_018229012  420 ---------htiesmfsrTGQNEHPYSIDLGSRG-LEafMDIHVTSLLLdveesfsvssmdcycsdgsvfrpglgkalpv 489  Pneumocystis ...
XP_011392222  418 ----------aatlltplSSEDP-EEDQCRVSLVvRGdtDEYFSNENVAv-----------------------------l 457  Ustilago mayd...
CCF51629      407 ----------aatlttssTSEDADEEDQCRVSLLvRGdtDEFYSNENVAv-----------------------------l 447  Ustilago hordei
GAC72297      397 ----------aatlttssTSEDADEEEQCRVSLLvRGdtDEFFSNENVAv-----------------------------l 437  Moesziomyces ...
GAC98902      408 ----------aavlhtsqTAEDADEEDQCRVSLLvRGdtDEFYSNENVAv-----------------------------l 448  Pseudozyma hu...
CBQ70904      409 ----------aatlttssISDDADEEDQCRVSLLvRGdtDEFFSNENVAv-----------------------------l 449  Sporisorium r...

4J2X_A         99 KNY--CTAKTLY---------------IS-DSD-KRKHFMLSVKMFYGN----------------SDD------------ 131 
Q5KPQ7        171 -----CAPQTHHmgrppditphlgtpgVE-DKKkERREEQKKLRTAALN------------------------------- 213  Cryptococcus ...
XP_006956985  295 -----ALARHLH---------------IT-DVAdDRKITNCYAEVVIPSllsr--------------------------- 326  Wallemia mell...
O74412        570 WGN--ALLKTIY---------------YTgQGKnDGFGRSTFLQLSVQS----------------KTK------------ 604  Schizosacchar...
XP_018229012  490 WGK--THLRTMY---------------IS-DRKeKIRSTCLKVQLHRKNkes---------------------------- 523  Pneumocystis ...
XP_011392222  458 DGRleTKMRSLY---------------VT-PTG-RSKSFRLQLNLLRPSglephlpifsplkksrAADalspamsigspa 520  Ustilago mayd...
CCF51629      448 DSQleTKMRSLY---------------VT-PTG-RSKSFRLQLNLLRPSglephlpifsplkksrTADalspamsvgspa 510  Ustilago hordei
GAC72297      438 DQTleAKMRSLY---------------VT-PTG-RSKAFRLQLNLLRPSglephlpifsplkksrAADplspaisagspa 500  Moesziomyces ...
GAC98902      449 DSRleTKMRSLY---------------VT-PTG-RSKAFRLQLNLLRPSglephlpifsplkksrASEavspaistespa 511  Pseudozyma hu...
CBQ70904      450 DSRleTKMRTLY---------------VT-PTG-RSKSFRLQLNLLRPSglephlpifsplkksrAAEalspamsvgspa 512  Sporisorium r...

4J2X_A        132 -------------------IGVFLSKRIKVISKPSKKKQS 152 
Q5KPQ7        214 -------------------AGFAATLPKNRNATDLKDRTL 234  Cryptococcus neoformans
XP_006956985  327 ----------------npfKGSFALPNMNIISKASKQRKP 350  Wallemia mellicola CBS 633.66
O74412        605 -------------------YFKLENLRLGVISKPSQKRAL 625  Schizosaccharomyces pombe 972h-
XP_018229012  524 -----------------fnFAQFQSSPICIISKAPQKKTS 546  Pneumocystis jirovecii RU7
XP_011392222  521 nepiengsevlsrlpkelaWASFESAPVTIISKSSKKTAK 560  Ustilago maydis 521
CCF51629      511 gdqadtsseplsrlpkglaWASFESAPVTIISKSSKKTAK 550  Ustilago hordei
GAC72297      501 ydqadsgsetlsrlpkglaWASFESAPVTIISKSSKKTAK 540  Moesziomyces antarcticus T-34
GAC98902      512 neqtdagsevlsrlpkglaWASFESAPVAIISKSSKKTAK 551  Pseudozyma hubeiensis SY62
CBQ70904      513 ndqadsntevlsrlpkglaWASFESAPVTIISKSSKKTAK 552  Sporisorium reilianum SRZ2
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