Conserved Protein Domain Family
SGL
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pfam08450: SGL (this model, PSSM-Id:400653 is obsolete and has been replaced by 462480)
SMP-30/Gluconolaconase/LRE-like region
This family describes a region that is found in proteins expressed by a variety of eukaryotic and prokaryotic species. These proteins include various enzymes, such as senescence marker protein 30 (SMP-30), gluconolactonase and luciferin-regenerating enzyme (LRE). SMP-30 is known to hydrolyze diisopropyl phosphorofluoridate in the liver, and has been noted as having sequence similarity, in the region described in this family, with PON1 and LRE.
Links
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Statistics
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PSSM-Id: 400653
Aligned: 42 rows
Threshold Bit Score: 183.229
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Download Cn3D
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q6FRB0        20 LSEGLTYIkeTDTLLWV------DIYRGEIHRLDSVSASGTAnhkvfnvsqstyssgaaIKYPKtptp---lreSVGCIF 90  [Candida] glabrata
Q5YUA4        31 WPECPRWH--EGTFWFS------DMYTGTLKTLDADGNATVV-----------------IDATGrgantdvpivLGGFGW 85  Nocardia farcinica
Q73TY7        30 FGEGPRWF--EGLLWFS------DMLGEAVHTTTMGGALTT------------------LPLPGh--------cPSGLGF 75  Mycobacterium a...
Q6N3R9        13 FPEGPVVMp-DGSVVLV------EIRAQQLTRVWPDGRKEVV-----------------AKVPGg---------PNGAAL 59  Rhodopseudomona...
Q8P3F8        62 WSEGPTWVrqGGYLLFT------DVPENKLYRWSDDSGLSVF-----------------LSPSGyagtdvaalrEAGANG 118 Xanthomonas cam...
Q89PW1        29 FTEGPIWHpiDHYLLFS------DMPGDVRRRWDARRGMAEV------------------KRPSn--------kCNGMTY 76  Bradyrhizobium ...
Q65UR9        95 WAEGPVWFgdGQYLLFS------DIPNNRIMRYDNITGQTAV-----------------FRENAn--------ySNGLAR 143 [Mannheimia] su...
Q89RF5        48 WAEGPVWFgdGRYLLCS------DIPNQRIIKWEEETGAVSV-----------------FRKPSn--------fANGNTR 96  Bradyrhizobium ...
Q7UTE9        24 LPEGPMAMvaDGKLSWVgiqhgaDVLHGSINVLDLATQTNQS-----------------HDLPG----------RPGFAF 76  Pirellula sp.
vbi:Avi_0916  17 LGEGPTYDvaRDTAWWF------DILGKGLIEHRFATGETIR-----------------HDLPM----------MASALA 63  Agrobacterium v...

Q6FRB0        91 PvitDGqvDTVLFGSKFGV----------------------GRC--QfssG----EWEYLTLYshcpelasgDRWLDLRS 142 [Candida] glabrata
Q5YUA4        86 L---PD--GRLIVVSMHEK----------------------LVLvhG---GgapdDLSVYADI---------SPYCSAAA 126 Nocardia farcinica
Q73TY7        76 R---PD--GSLLIASTRDR----------------------RVLryD---GetvvTVAELADI------------APADL 113 Mycobacterium a...
Q6N3R9        60 G---PD--GKMYICNNGGFgwfpsrgtmmpgapapheyiggSIQrvDlqsG----EVETLFDKc--------GEHPLKGP 122 Rhodopseudomona...
Q8P3F8       119 Lf--AEpgGTVLLADSGTR----------------------IVArlDpatR----TKTPLATSf-------dGK-RFNSP 162 Xanthomonas cam...
Q89PW1        77 D---AE--LNLIVCEHATS----------------------SLIreRp-dG----RREVLASHf-------gGQ-ELNSP 116 Bradyrhizobium ...
Q65UR9       144 D---KQ--GRLLACEHLTR----------------------RLTrtEy-dG----SVTVLADSf-------eGK-PLNSP 183 [Mannheimia] su...
Q89RF5        97 D---RQ--GRLVTCEHGGR----------------------RVTrtEy-dG----SITVLMDSf-------gGK-RLNSP 136 Bradyrhizobium ...
Q7UTE9        77 Q---CRtaGKFVAGVERSL----------------------GIF--DinsG----EWTPFFDGv-------dSDVTNTII 118 Pirellula sp.
vbi:Avi_0916  64 Ti--DA--ERQMLATEQGI----------------------FIR--AiasG----ELTLLTALe-------pER-PGNRS 103 Agrobacterium v...

Q6FRB0       143 NDGNVSPDGKsLYVGVMCDFHVPMQDI--------GAIVRVDLVg-SAalplpVHLVIDRVKIPNAIHWNSAGTKMYW-- 211 [Candida] glabrata
Q5YUA4       127 NDMVVDADGR-AYITQLGFDIFKGDEPt------tSPLIVVEPD--GTv---gTPEKVGPLNCANGIAISADGTKLYT-- 192 Nocardia farcinica
Q73TY7       114 GDMVVDRAGR-AYIGCQAFTG--------------GAIIRLDPD--DR-----ATVVADDLDFPNGMAITPDGATLIV-- 169 Mycobacterium a...
Q6N3R9       123 NDLVFDKHGG-LWFTDLGKRRARDMDV--------GAAYYIKPGm-TE-----ITEQVFGTLPLNGIGLSPDEATMYA-- 185 Rhodopseudomona...
Q8P3F8       163 NDVVRRKDGV-VFFTDPPYGLKGMNDSpvke-lrfNGVYRLDTD--GS-----VHLLDDSLSFPNGIALSPDQRTLYV-- 231 Xanthomonas cam...
Q89PW1       117 NDVCVHSSGA-IYFSDPWYGRMPVYGVerprqlgfQGVYRVMPGgePK-----LVVDRNLFDQPNGLCFSPDERLLYV-- 188 Bradyrhizobium ...
Q65UR9       184 NDIAVQSNGA-IWFTDPTFGINGYYEGekakaeqpTAVYRIDPQt-EK-----LERVLNDLLMPNGIAFSPDEKHLYIvg 256 [Mannheimia] su...
Q89RF5       137 NDVVVKSDGS-VWFTDPTFGLLGNYEGykaepeiePNVYRLDPAt-GK-----ANIVAEGVLGPNGLCFSPDEKILYVve 209 Bradyrhizobium ...
Q7UTE9       119 NDGLAIDDN--LIFGTKDLEFAEKK----------AGLYLYRGSd-KK-----LIRLRDDQICSNGKMIRRDDSGKLFll 180 Pirellula sp.
vbi:Avi_0916 104 NDGRVHPCGA-LWIGTMGKTAADGA----------GAIYHVAGD---K-----VTRLYDSISIPNAICFSPDGSLGYY-- 162 Agrobacterium v...

Q6FRB0       212 ---TDSLHFC--LWEQDGDDSST----KKKL-IDVQRHnpef---espePDGSATDLvNNVVYVCVW-----STH----- 268 [Candida] glabrata
Q5YUA4       193 ---AEVMAFK--ITVIDRAADGSls-nPRDF-ATCPFM-----------PDGIGLDD-EGGVWAAMP-----GGG----- 243 Nocardia farcinica
Q73TY7       170 ---AESTGRR--LSAFAIDDDGAls-gRRVF-ADGLDGp----------PDGIALDA-DGGVWAAMT-----LAH----- 221 Mycobacterium a...
Q6N3R9       186 ---AETPTGR--LWAFDLSGPGEvk-pRDVI-YRGEKGkpicglggyqmFDSLAVEA-SGNVCVATL-----VSG----- 247 Rhodopseudomona...
Q8P3F8       232 ---ANSDPARpiWMAYALDAQGAvt-gKRVF-ADATDLvnkd---tpglPDGMAVSA-DGRLFAT-------GPG----- 290 Xanthomonas cam...
Q89PW1       189 ---NDTVQAL--IRVFDVNADGTls-nARVFaSSIKSElep------glPDGMKCDQ-HGNVWVTAP-------G----- 243 Bradyrhizobium ...
Q65UR9       257 rfsETPALRE--IFRYDVSTDGKln-nRTHF-FDGGENg---------tLDGIAVDE-DGNIWAGWGsinnsKNGlsgdm 322 [Mannheimia] su...
Q89RF5       210 --sRGVPNRK--ILAYDVSADGTtisnKRVH-IDAGPGt----------PDGMRCDI-DGNLWCGWG-----MGDpe--l 266 Bradyrhizobium ...
Q7UTE9       181 --dIDSPTRK--VVEYPLDIEAGtigeARVV-LDLTDDpg--------vPDGAILTPdGKGIIVAIFhpgvaEHG----- 242 Pirellula sp.
vbi:Avi_0916 163 ---VDTRVNT--LMKVSLDPATGlptgTPSVhIDGRGKdg--------gIDGAVCDA-EGGLWNARW-----GVG----- 218 Agrobacterium v...

Q6FRB0       269 -KVQKYSLEdGtLLHEYVLPqSTpRISSCCFvG----RDLCITTAN 309 [Candida] glabrata
Q5YUA4       244 -YVARFTEQ-G-ITDAVPMPlENgIASACLL-GgpdrNRLYMTVGF 285 Nocardia farcinica
Q73TY7       222 -QFERIVAG-GaVSDRIDIG--DrVAIACAL-GgpqrRTLFLLSST 262 Mycobacterium avium subsp. paratuberculosis
Q6N3R9       248 -CISVIAPD-GtLVE--QVPtGDrVTTNIAF-GgpdlKTAYITLSG 288 Rhodopseudomonas palustris
Q8P3F8       291 -GVIVFDPD-GrRLGRIETGa---AISNCAFgn--dgHTLYMTSHA 329 Xanthomonas campestris pv. campestris
Q89PW1       244 -GVWVYSPR-GeLLGKVRVPe---LVANLAW-GgpdfRTLYLTSTH 283 Bradyrhizobium japonicum
Q65UR9       323 dGVIVINPQ-GkQIAHIHLPe---RCANLCF-GgskrNRVFMASGH 363 [Mannheimia] succiniciproducens MBEL55E
Q89RF5       267 dGVVVFAPD-GvMIGRIALPe---RCANLCF-GgvkrNRLFMAASQ 307 Bradyrhizobium japonicum
Q7UTE9       243 -ETRLYDLAtGeLRTIWQTP-GSpQNTCPALvPhegkLKLVITTAI 286 Pirellula sp.
vbi:Avi_0916 219 -AVDHYDRT-GqHLARYRLP-AA-QTTCPAF-IgakaDRLLVTSAT 259 Agrobacterium vitis S4
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