6G2J


Conserved Protein Domain Family
NDUF_B8
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pfam05821: NDUF_B8 (this model, PSSM-Id:399079 is obsolete and has been replaced by 428637)
NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)
This family consists of several eukaryotic NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI) proteins. NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Its main function is the transport of electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits.
Links
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Statistics
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PSSM-Id: 399079
Aligned: 6 rows
Threshold Bit Score: 250.144
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6G2J_LL        28 RAFHMT------KDMLPGSYPRTPEERAAAAKKYNMRVEDYEPYPDDGM--GYGDYPMLPNRSQHERDPWYQWDHSELRM 99  
EOA97283        7 AASGLT------SEMLPGPYPRTPEERAAAAKKYNMRVEDYQPYPDDGL--GYGDYPMLPKRSAHERDPWYQWDQPDIRH 78   mallard
NP_001138314   28 TASHVT------KDMFPGPYPKTPEERAAAAKKYNMRVEDYEPYPDDGM--GYGDYPKLPDRSQQERDPWYDWDHPDLRL 99   pig
Q6P5L5         30 AASGSS------KDSLPGPYPKTAEEKAAAAKKYNMRPEDYQPYPDDGW--GSGDYPMLPSRSQHERDPYYQWDHPDLRR 101  zebrafish
Q9XWJ6         24 MRGPLTfdgwypRDHKPSAPPTNEEERRAAAVKYGLRPEDYQSMDKDDVikFAGDYPDLGVITYDHKDPYEAWTDRQNRR 103  Caenorhabditi...
PDM62081       23 LRGPLTfdgwypRDHKPGQYPENEEERRRAAIKYGLRPEDYKPMDKDDIvrYAGDYPDLGVVTYDHKDPYESWTDRNHRR 102  Pristionchus ...

6G2J_LL       100 NWGEPIHWDLDMYIRNRVD----TSPTPVSWDVMCKHLFGFVAFMVFMFWVGHVFPS----YQPVGPKQYPYNNLYLERG 171 
EOA97283       79 NWGEPMHWDFDMYIRNRFD----TSPTQIPWHTMRKHFLVFLSTMLIMFGIGEFYPS----YRPVGPKQYPFNDLYLERG 150  mallard
NP_001138314  100 NWGEPIHWDLDMYIRNRVD----TSPTPVSWNTMCKHLSGFVAFMLFMFWVGEIYPS----YQPVGPKQYPYNDLYLERG 171  pig
Q6P5L5        102 NWGEPMHYHFDMYIRNRVD----TSPTPLDWRTMRLWLFGFLGLTMFMFGMGEVLPS----YQPVAAKQYPYNNLYLERG 173  zebrafish
Q9XWJ6        104 NWGELVPIDMMRYRGDRLTftglEAEDYTTWNSIVMCLRVLVPMALLAWYFTNEHPNalrwKNPAMPKQYSYDFYRAYPF 183  Caenorhabditi...
PDM62081      103 NWGEMVGMDMMNYRGDRLTftglEAEDYTTWASIKMCLRVLVPMALLAYYFSREDPNafrwKNPAMPKQYPYDFARSFPF 182  Pristionchus ...

6G2J_LL       172 GDPTKEPepVVHYDI 186 
EOA97283      151 GDPNKEApvVTHYEI 165  mallard
NP_001138314  172 GDPTKEPepVVHYEI 186  pig
Q6P5L5        174 GDPEKEPepVKNYEI 188  zebrafish
Q9XWJ6        184 DDPRKYP--IVNYSF 196  Caenorhabditis elegans
PDM62081      183 DDPRKFP--IVNYSF 195  Pristionchus pacificus
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