Conserved Protein Domain Family
UPF0160
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pfam03690: UPF0160 (this model, PSSM-Id:377098 is obsolete and has been replaced by 461014)
Uncharacterized protein family (UPF0160)
This family of proteins contains a large number of metal binding residues. The patterns are suggestive of a phosphoesterase function. The conserved DHH motif may mean this family is related to pfam01368.
Links
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Statistics
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PSSM-Id: 377098
Aligned: 206 rows
Threshold Bit Score: 222.375
Created: 6-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q4CZB7               32 VIGTHNGSFHCDEAMACGLLRCSqnFGQSNILRSRDPNALE------RCNIVVDVGSVYDEATLRFDHHQPSFHDTMKTP 105 Trypanos...
EHY64553             12 HIVTHDGAFHLDDVLACFILRVI--YPHAKITRTRDLEKIK------TGDIVVDVGAEFNEKTLRYDHHQRGFKETYNES 83  Nematoci...
EIJ88420             12 TIITHDGAFHLDDVLACFMLKKI--YPHANIVRTRNEDIIK------TGDIVVDVGGVFDPANFKYDHHQRGFNQTYNDN 83  Nematoci...
WGS:AFBI:EDEG_02164   2 yLITHNGKFHLDEILACVILEKL--YPNSTLLRTRDRKEIKrlvdenKHVAVFDVYDQFDHSLRLYDHHQRCFNDTFSSD 79  Edhazard...
ELA45884              2 KLATHNQRFHLDEVTSTAILKKI--FPDATLKRTRDPKDFE------EADIVYDVSGVYDPTRGRYDHHQRGFTHTFSEA 73  Vavraia ...
EED43680             13 TLITHSGSFHYDELLATAFLMEL--FDDVILLRTRDPKIIK------TGTIVYDVGFEFDPANKRFDHHMKWFSEVFSED 84  Enterocy...
ELA42409              2 KLVTHDGNFHYDEILATAVLLKI--YPDAEVIRTRVREVIN------TGDIVYDVGQTYDPSKYRYDHHQNTFHDTYSPQ 73  Vittafor...
Q8SUU4                2 ILVTHDGKFHLDEVMATAVLLKI--YPDSEIVRTRSSAVVR------SGDIVYDVGRSFDPEANRYDHHQESFNETFSPK 73  Encephal...
Q8SW07                2 KLITHNERFHYDEVLASCILLRI--YPDAEIVRTRDKTLID------SGDIVYDVGGVFDPGLGRFDHHQRTFFETFSPK 73  Encephal...
EOB13648             10 KLITHDERFHFDEVLSTAILKRI--YPNATVIRTRDNEIIK------TGDIVYDVGGIIDPSLGRFDHHMNFFTETYSDK 81  Nosema b...

Q4CZB7              106 kaaYQTRLSSAGLVYKHFGREIIQGY--VEsalaspyrvklldatkwgtdkkkLSEQELDILFDIVYKNFVEHIDGIDNG 183 Trypanos...
EHY64553             84 ---NNIILSSAGLVYKYHGLEFIKKLgl-----------------------dlPIDFNYSMLMEILYDTYFVSVDANDNG 137 Nematoci...
EIJ88420             84 ---YDIKMSSAGLVYKYHGMQFIKALgl-----------------------dvHPDFDYLLLLGLLYETYFVSVDANDNG 137 Nematoci...
WGS:AFBI:EDEG_02164  80 ---YDVKLSSAGLIFKYYGKQFILAFfsDIe----------------------LSSEILEYLYIKIYEEYFLYEDAIDNG 134 Edhazard...
ELA45884             74 ---FPIKLSSAGLIYKHYHKQLFKYYgl-----------------------vaE-----DWIVDEVYEEYFKYVDACDNG 122 Vavraia ...
EED43680             85 ---YNVKLSSAGLIYKYYHEAVFKKYgl-----------------------hsNDILIFNYIKNKMYKELFLATDAIDNG 138 Enterocy...
ELA42409             74 ---YNIRLSSAGLIFKHFHDKLFERYgfTR------------------------QSTIFEEIVEKVYFEFFLPADAIDNG 126 Vittafor...
Q8SUU4               74 ---HKIKLSSSGLIYKYYGEKFLEKYglNR------------------------TDECFPRVLEEVYTAYFMSADAIDNG 126 Encephal...
Q8SW07               74 ---YSVKLSSSGLIFKYFHRKLLSLYgiES------------------------SSRTYDLVVDKIYSEFFLYADAIDNG 126 Encephal...
EOB13648             82 ---YKIKLSSSGLVFKYFTEEIMETFnvKK-----------------------VDDDLYDWLISKVYERYFLPADAVDNG 135 Nosema b...

Q4CZB7              184 VN-AYGpaetegeegavpvsssspsCVKKYNVST-TLSARIGNLMP---------------WWNEeg------------- 233 Trypanos...
EHY64553            138 VD-----------------------IADEVKYNErSLDNVIRSFVPcdipe----------------------------- 165 Nematoci...
EIJ88420            138 VD-----------------------ISDDVRYNErTLDNVIRSFVPfdipe----------------------------- 165 Nematoci...
WGS:AFBI:EDEG_02164 135 ID-----------------------VGQKYKIR--SLPDMVDNMYK---------------------------------- 155 Edhazard...
ELA45884            123 VD-LQCt------------------IVPR------TMVDLVSCFNVqetgvkedtkngqmkNEVGgattagssarvhssc 177 Vavraia ...
EED43680            139 IE-ITYs------------------IKPR------TIQDIIKLFNTsyid------------------------------ 163 Enterocy...
ELA42409            127 YDsVFGa------------------IRAR------TVADVVKNFNVys-------------------------------- 150 Vittafor...
Q8SUU4              127 YE-IFGe------------------IVPR------SLSHVVESFNAld-------------------------------- 149 Encephal...
Q8SW07              127 QD-IYGe------------------IKPR------SIADLVNLFNVd--------------------------------- 148 Encephal...
EOB13648            136 VD-IYGe------------------IKPY------TIYDLVENLNNhe-------------------------------- 158 Nosema b...

Q4CZB7              234 -----------nGKVENENAAFLQAMELATSEFFDSV--HY-HVFAWMPARGIVRAAFLE--AmnvhPSG--RIVVF--- 292 Trypanos...
EHY64553            166 -------gtsfeRASTMRYQAFESAMEYIGQDLLRHC--KN-MIFQIIKNSRATQECFNSmkD----PSA--RYLVM--- 226 Nematoci...
EIJ88420            166 -------gesieYGDKVRYEAFEKAMEYIGSDLVRHC--KY-LMHQINKDKMPILQSFNQmkD----PRS--RYIIM--- 226 Nematoci...
WGS:AFBI:EDEG_02164 156 ------------GSSEKSEEIFFNAKKFVRNDFYLYLnsKRkDIALISELRAIVKKTDKN------------DFFIYvge 211 Edhazard...
ELA45884            178 tvplsdtlkdfvLSDNYNDYNFLCALNLISIDMDNYF--RQ-K-KQLVEMVSANHDLIRS-------ATGdiLVIGP--- 243 Vavraia ...
EED43680            164 ---------dmdEYNVAQDSQFHKALEFVKMDLKNYL--NN-LFNNFLPGFRKAIDLLQN-------NKDpdIIVIT--- 221 Enterocy...
ELA42409            151 ----------enTMTRDENLRFETALDFVSMDLDNYL--KY-VLCEYALSYEHFYNVLKD-------FAG--DIFVT--- 205 Vittafor...
Q8SUU4              150 -----------fSDSDRQNKRFLEAVQFVSKDLDNFI--SA-IVNRWVPSYKYLNKLIAE-------VNG--DILYV--- 203 Encephal...
Q8SW07              149 -----------gSGRDAETEGFYEALRIVDKDLDNYM--KR--IKLWTDNYEHMENKIKE-------TSG--PILVL--- 201 Encephal...
EOB13648            159 -----------dLVCEKQTEQFYKAVEIVSLDFENFM--TK-LLNCWYYKFIEIEKLLSN-------HDD--YILVS--- 212 Nosema b...

Q4CZB7              293 KDCfCPWKEHLLELE--EEHGkvGHVLYVLFa----dKKGWRVQAVPKEASGFENRKSLP--WRGLRDEELSQASGIEGG 364 Trypanos...
EHY64553            227 EGGkFPVREILYYYN--GLLQ--RNVSIVIYqvsgrnSYTYKIICIPKKGVKYTPEIPLCeeWRGIRDEELQKYPNMMGA 302 Nematoci...
EIJ88420            227 GSGaYPAKELIQYYN--TSLN--RNVSIIIYkirsreGTIYKLLCIPKKGIRYTPEIPLCeeWRGLRNEQMRRFPKLKKA 302 Nematoci...
WGS:AFBI:EDEG_02164 212 NKN-CSSIIHFL--E--KKYD--RDFKFIIQk----eEEQFRVYAIAITALSFKTKCPLQekWRGLRNEELQRISGIDDA 280 Edhazard...
ELA45884            244 DRD--LSREALFILE--KIWK--KDFLFIVYd----sSEHVRMYGTIKERNSYAIKVPLCleWGGLREEELRARSGIEGS 313 Vavraia ...
EED43680            222 DNY--ISISAIVEAE--RFTS--RDLKYMIFk----kNNEYRIYCFNIPEHDFQPKVPLKqeWRGKSQEELKTISQIPGI 291 Enterocy...
ELA42409            206 DKK--VATDLLY--ElnEKLQ--KNIKFIIVk----nDNDFRIITIPVERGKFAIKYPLHpkWRGLSGTNLDEVSGINGC 275 Vittafor...
Q8SUU4              204 DRY--CFVDVIPEIE--KKYK--KDVKFVLNr----kESSVSILTVPKDRKRFESKVPLKkeWRGLAGGKLETVSGIDGC 273 Encephal...
Q8SW07              202 DKH--YSTDLVLEIE--AQNG--KDFKFMVFp----hRGAYRVIAIPKHKGTFETKNPLRkeWRGLVNEELVEASGIEGC 271 Encephal...
EOB13648            213 DTY--IYPNLILDVE--RRLN--KNILFLVFp----sMGKYKIRAINEDKKTFKSKLPLKaeWRGKREEELKDL--IEGG 280 Nosema b...

Q4CZB7              365 IFVHVSGFIGGNKTYEGALQMAVKAL 390 Trypanosoma cruzi
EHY64553            303 MFVHGTGFCGEANNLKTAIYMVERSI 328 Nematocida sp. 1 ERTm2
EIJ88420            303 SFVHATGFCGSAMDLETAEYMAQKSI 328 Nematocida parisii ERTm3
WGS:AFBI:EDEG_02164 281 LFVHSTGFLGITKSYDNAVKMCELSy 306 Edhazardia aedis USNM 41457
ELA45884            314 TFVHSSGFTGGAKDLKSALEMCRRSI 339 Vavraia culicis subsp. floridensis
EED43680            292 RFVHATGFTGSVDTLDSAIMMCHESL 317 Enterocytozoon bieneusi H348
ELA42409            276 VFVHASGFTGGNSTLEGAVEMCRKSL 301 Vittaforma corneae ATCC 50505
Q8SUU4              274 NFVHASGFVGSNKTIEGAMEMCRISI 299 Encephalitozoon cuniculi
Q8SW07              272 TFVHSSGFMGINSTLENALKMCTESL 297 Encephalitozoon cuniculi
EOB13648            281 FFVHSSGFIGVNRTLEGAIKMCRETf 306 Nosema bombycis CQ1
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