Conserved Protein Domain Family
Glyco_tran_10_N
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pfam17039: Glyco_tran_10_N (this model, PSSM-Id:374959 is obsolete and has been replaced by 465336)
Fucosyltransferase, N-terminal
This is the N-terminal domain of a family of fucosyltransferases. This enzyme transfers fucose from GDP-Fucose to GlcNAc in an alpha1,3 linkage. This family is known as glycosyltransferase family 10. The N-terminal domain is the likely binding-region for the fucose-like substrate (manuscript in publication).
Links
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Statistics
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PSSM-Id: 374959
Aligned: 81 rows
Threshold Bit Score: 79.6264
Created: 22-Apr-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q11127         87 QRLVGVLLWWEpf----rGRGGYpksPPDCsl-rfNISGCRLLTDRAAYGEAQAVLFHHRDlvKELHDWPppwgarertd 161 house mouse
CAD43602       51 RKNVTIYVATTyygdpidAEma----flTCpe---lkKFCRVTRNFSEASTSDALLFHSRNffEAVKILPn--------- 114 Caenorhabditis...
16_pfamImport   1 NSSGVILLWSHpwg-----------lwdTSapegsTFGRCKITYNRARISEAHAVVFHLTA--VFPNDIPwk-------- 59 
XP_002130364   50 RSSGVLLMWDHpwa-----------vgfTSepegtRFGRCNLTYKRERIEEADAVIFHLTT--ISKKDIPwq-------- 108 vase tunicate
18_pfamImport   1 AKPKLILYWGLafgde--------------rgretSTGECEVTYDRNRLKEARIVAFHKTT--ISAKDIPwt-------- 56 
19_pfamImport   1 EKPKLILYWRPd----------------GSsgeetSVGECEVTYDKNRLKEAGIVAFHFTT--ISGNDIPwk-------- 54 
XP_004226468   61 KKSPLILYWGKaw-------------giNGpeegsLMDECILTYNRSKISDAIAVVFHFTT--INGNQIPwq-------- 117 vase tunicate
NP_001027791   74 iPRPIILMYYKp------yDGFA---FPKVlk-tvAGHECETTFDRSKLDQSEAVVFYYSRvlINGGPDP---------- 133 vase tunicate
XP_002125006   53 KNKPLLLYWG------------------NTyedagLNIECSVTYDQSRLPDADAVIFHFDK--IRKRDMPwk-------- 104 vase tunicate
CAH04970       58 EERSLILYWDYpwh-----------dkaSGapegdVMGNCIQTYDRSKIKEAKAVVFHYTI--IGKKDIPwth------- 117 Pacific transp...

Q11127        162 kalvlrvfddqegavtltgkaletVGSRPPGQ------------RWVWMNFESPSH-----TPGlr---gLAkDLFNWTL 221 house mouse
CAD43602      115 -----------------------lKKLRKPNV------------PWILWNIESPSHeq----------lpTEkNLFNWTM 149 Caenorhabditis...
16_pfamImport  60 -------------------------ynRRRNQ------------LYVYWSMENPWVmrylyKRDfkr----fnNFFNMTM 98 
XP_002130364  109 -------------------------hyRSPKQ------------LFVFWSKENPWAmrylyRTDfk---aFD-NFFNMTM 147 vase tunicate
18_pfamImport  57 -------------------------hyRIKSLihldlytfnffiIFLTYNn------------------lFD-NFFNWTW 92 
19_pfamImport  55 -------------------------hyRDPKQ------------IFVYWNAEPAGAwgrd------slteFD-NFFNWTW 90 
XP_004226468  118 -------------------------hyRDKRQ------------IFVWWCAEGPRLfgrn------glreFDgGFFNWTW 154 vase tunicate
NP_001027791  134 ------------------------KS-RKRNQ------------KYVYFDLEPTWA-----LQGmnysigEN-GFFNWTM 170 vase tunicate
XP_002125006  105 -------------------------nyRDKHQ------------IFIWWCAEAPAIfgrn------alreFD-GFFNWTW 140 vase tunicate
CAH04970      118 ---------------------ysiYSYRDPGQ------------IYVWWSAEGPAIlqmegVDlp----pFN-GFFNWTW 159 Pacific transp...

Q11127        222 SYRTDSDVFVPYG 234 house mouse
CAD43602      150 TYRRDADLWAPYG 162 Caenorhabditis elegans
16_pfamImport  99 TYRRTADIYDSYG 111
XP_002130364  148 TYHKNSDLYSGYG 160 vase tunicate
18_pfamImport  93 TYKRSSNALRGYG 105
19_pfamImport  91 TYKRSADALRGYG 103
XP_004226468  155 TFKRSADVLRYYG 167 vase tunicate
NP_001027791  171 SYKRTSSIYFPYG 183 vase tunicate
XP_002125006  141 TYKRDADVQRLYG 153 vase tunicate
CAH04970      160 TYRQDADVFRGYG 172 Pacific transparent sea squirt
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