Conserved Protein Domain Family
MBDa
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pfam16564: MBDa (this model, PSSM-Id:374634 is obsolete and has been replaced by 465179)
p55-binding region of Methyl-CpG-binding domain proteins MBD
MBDa is a second MBD domain of Methyl-CpG-binding domain proteins. region implicated in binding the RbAp46/48 (retinoblastoma protein-associated protein) homolog p55, which is one of the components of the MBD2-NuRD complex. The MBD2-NuRD complex is a nucleosome remodelling and deacetylation complex.
Links
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Statistics
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PSSM-Id: 374634
Aligned: 30 rows
Threshold Bit Score: 83.4863
Created: 25-Apr-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WGS:AADE:GA20899-PB  53 VDVFYYSRaLRTDVSLVPPIRQTASIFKQPVTPIGNHtqDPSKVKHDSKHGAQEKPKQLFWEKRLERLR 121 Drosophila pseudoob...
Q3UXB0               36 VPKKIKAK-HRTGVTSKDSMRMTSCIFAKPVTTITSY--PENETRYRREEDKLTKPKQLCALKRLKKHQ 101 house mouse
XP_003432915        111 QVHLAKTK-RRCHERVALPVRLTSCILKRPVTRITSH--PDNEVRYNERERTLEKPQQICAYRRLQGLQ 176 dog
XP_012900931         32 QVHLTKAK-KRHHERIAPPTRLTSCIFKRPVTSITSH--PGNEVRYNQWDRTLEKPQQISAYSRLQGLQ 97  domestic ferret
ELK12830             11 EVHLAKTK-RRHRERSALPMRLTSCIFKRRVTRITSH--PGSEVRRRQWDETLEKPQQVCAYRRLQGLQ 76  black flying fox
XP_006077791         50 QYYLDKSE-QSHCDETALPIRLTSCIFQRPVTRITPH--PGNVVRHRQCEGTLEKPQQVCAFRTLQGLQ 115 water buffalo
XP_019818948         10 QEILVKAK-QRRRDRCLLPLRLTSCIFQKPVTRITSH--PGNVVKRRPCEETLEKPQQAFAFRRLQGLQ 75  zebu cattle
XP_012669416         21 ellIAKTN-QRRVLRSELPTRLTSCIFPKPVTRIRSH--LDNAVRRRPRDKSLEKPQQLCAYRRLQGPQ 86  small-eared galago
XP_002723567         12 VARVLKAK-PRPGAGSAQPVRLTSCIFKSLITRVSAH--PGNVVQHLLTEGYLEKPQQVCALRRLQGLC 77  rabbit
XP_008774871         15 aQSKTKTK-RRSGGTFKDPLRRTSCIFPQPVTLITSY--SENKTRYRRDEAKLQKPEQLCALQRLENLQ 80  Norway rat
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