4CPG


Conserved Protein Domain Family
SGTA_dimer
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pfam16546: SGTA_dimer (this model, PSSM-Id:374618 is obsolete and has been replaced by 465168)
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Homodimerization domain of SGTA
SGTA_dimer is a short N-terminal domain at the start of SGTA or small glutamine-rich tetratricopeptide repeat-containing proteins. It is the homodimerization domain of the SGTA, a heat-shock protein (HSP) co-chaperone involved in the targeting of tail-anchor membrane proteins to the endoplasmic reticulum. This N-terminal homodimerization domain mediates the association with a single copy of Get4 or Get5 proteins, providing a link to the rest of the GET pathway.
Links
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Statistics
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PSSM-Id: 374618
Aligned: 88 rows
Threshold Bit Score: 60.6069
Created: 25-Apr-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4CPG_A          19 KRLAYAIIQFLHDQLRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLAL----PQTLPEIFEA 78   human
Q21746          24 QNLVVSFLQFIRQKVSQNQATAEQAEALEVAIQCLEHSFGLDDASYAFQP----SRPILELFKS 83   Caenorhabditis elegans
1_pfamImport     3 KNLIVAFLQFIRAKSGQGPISQEQAETLEIAIQCLEGTFNIDDGSYAFQP----SRPLIDLFTE 62  
Q28H19           5 KRLAFSIIRHLHDQLRNGGLSSDAQESLEVAIQCLETAFEVSIEDSNLAV----PRSLQEIFTE 64   tropical clawed frog
EEC14987         5 KRLVLSIVQFLRQQLQTADLSSDAKESVEVAVQCLETAYGVSIDDLSNDSll-vSRTLLDIFRE 67   black-legged tick
12_pfamImport    2 KHLVYSIIQFLCEQLQSGNLTADATESIEVAVQCLEQAYSISHDDAKGRAs---SKNLLEMFKE 62  
EEN47402         7 gKMVFAIIDFLNDQLHSGQLSGDAAESLEVAIQCLETAYGIEYKDAACVArlhtKPPLYELFLs 70   Florida lancelet
EPY52792         4 KKVATAVIDFLNQATATSAVSDEEKESLEVAAQCIKDSFKVEPNEITPGS----GKRLVDAYEA 63   Schizosaccharomyces cryophil...
XP_786841        5 NRLVFAIVEFLDQQVRSNAVSGEALESLEVGLQCLQTAYGISLDDPALTSqk-tERSLLEIFTS 67   purple sea urchin
PDM61262      1087 KNLAVSFIQFIRHKVSANQCTDDQIEALEVAVQCLESAFALTDANYAFQP----SKSLLALFTA 1146 Pristionchus pacificus
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