3HM5


Conserved Protein Domain Family
SANT_DAMP1_like
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pfam16282: SANT_DAMP1_like (this model, PSSM-Id:374469 is obsolete and has been replaced by 465084)
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SANT/Myb-like domain of DAMP1
This domain, approximately 90 residues, is mainly found in DNA methyltransferase 1-associated protein 1 (DAMP1) that plays an important role in development and maintenace of genome integrity in various mammalia species. It mainly consists of tandem repeats of three alpha-helices that are arranged in a helix-turn-helix motif and shows a structual similarity with SANT domain and Myb DNA-binding domain, indicating it contains a putative DNA binding site.
Links
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Statistics
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PSSM-Id: 374469
Aligned: 114 rows
Threshold Bit Score: 101.001
Created: 24-Apr-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3HM5_A           5 YPFARFNKTVQVPVYSEQEYQLYLHD-----------DA----WTKAETDHLFDLSRRFDLRFVVIHDRYDHq----qFK 65  human
ESW97176       108 YNFAKYNTSLDIPSFSKEEYDEKLK-------------DlsedWTFEETKFLFDLAKDYDLRWAVVYDRYEFh----nDK 170 Ogataea parap...
CCD27406       117 SKFAKFNTHLSIPSFTREEYASFMNLkdn-----nesADasstWAFEEVIYLFDLCKLYDIRWFIINDRYLFvdsngkRS 191 Naumovozyma d...
EJS43719       109 SAYSKFDQHLSIPTFTKEEYDSFTNEtgnqe-svvneKNeknkWSFEEIEYLFGLCKQYDLRWFLIFDRYSY------NE 181 Saccharomyces...
CCK70087       116 STFLKFDQHFTLPTFTKEEYDEFMKPqnds---ssntEEnenrWSFEEVDYLMQLCKKYDLRWFVIEDRYNFg-----ES 187 Kazachstania ...
Q6CSS3         110 SSFAKFNQHLTIPSFDEQEFQQFMN-------------GnnseWKYGEVQYLFDLCRNYDMKWFVIADRFNYn-----GT 171 Kluyveromyces...
Q752S6         108 SSFAKYDQKLTLPEFTEGEYQEFMAQaak------gaNSdaptWSYEEVQYLFDLCRRYDLRWHIVYDRYMY------DE 175 Eremothecium ...
ybcl:Ecym_1441 108 NTFSKYNQKLTIPEFSKEDYEEFMSGshdkasskesgDDtiqvWEYDEVKYLFDLCKKYDLRWYIIYDNYSY------DE 181 Eremothecium ...
CAR23410       107 SSFSKYNTKLTIPAFSEEEYLSFMGYtt-------pgSNplkeWDYEEVQHLFDLCRKYDLRWFIIQDRYEG------KL 173 Lachancea the...
CCC67084       114 SNFTKYDIHLSIPEFSEEEYNSFMNPqtkstesnetdNKpehkWSYVEILYLFGLCRRYDLSWFVIYDRYNF------GE 187 Naumovozyma c...

3HM5_A          66 KRSVEDLKERYYHICAKLA 84  human
ESW97176       171 HRSLEDLKERLYSVSAKLL 189 Ogataea parapolymorpha DL-1
CCD27406       192 DRSVEDLKEMFYKVSKNYF 210 Naumovozyma dairenensis CBS 421
EJS43719       182 SRTLEDLKEKFYHICRNYF 200 Saccharomyces arboricola H-6
CCK70087       188 VRSLEDLKEQFYEVCRRYF 206 Kazachstania naganishii CBS 8797
Q6CSS3         172 ERKLDDLKEMFYTVCQWYF 190 Kluyveromyces lactis NRRL Y-1140
Q752S6         176 SRTMEDIREMFYTVCQKYF 194 Eremothecium gossypii ATCC 10895
ybcl:Ecym_1441 182 KRTLEDLKEAFYKVCKAYF 200 Eremothecium cymbalariae DBVPG#7215
CAR23410       174 FGTLEDLKDAFYTVCHRYF 192 Lachancea thermotolerans CBS 6340
CCC67084       188 EKSLEDLKEMFYEVCRKYF 206 Naumovozyma castellii CBS 4309
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