4C8V


Conserved Protein Domain Family
Furin-like_2
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pfam15913: Furin-like_2 (this model, PSSM-Id:374219 is obsolete and has been replaced by 464939)
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Furin-like repeat, cysteine-rich
The furin-like cysteine rich region has been found in a variety of proteins from eukaryotes that are involved in the mechanism of signal transduction by receptor tyrosine kinases, which involves receptor aggregation.
Links
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Statistics
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PSSM-Id: 374219
Aligned: 17 rows
Threshold Bit Score: 155.223
Created: 26-Apr-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4C8V_A         9 C-KGCLSCSKDNGCLRCQPKLFFYLRREGMRQYGECLQSCPPGYYGVRGPDMNRCSRCRIeNCDSCFSRDFCIKCKSGFY 87  tropical clawed...
Q2I0M5        35 C-TGCIICSEENGCSTCQQRLFLFIRREGIRQYGKCLHDCPPGYFGIRGQEVNRCKKCGA-TCESCFSQDFCIRCKRQFY 112 human
EHA97268      35 L-SFQLSCGSERGCMACQQRLFLLIRREGIRQYGKCVHDCPLGFFGIRGQEVNRCKKCGA-TCDSCFSQDFCIRCKRRFF 112 naked mole-rat
XP_008118101  86 CdKGCDLCSEFNGCLRCCPRLFILLERNDIRQTGICLQSCPSGYFGLRNPDMNKCIKCKIeNCEECFSRNFCTKCKEGFH 165 green anole
XP_014348294  36 C-SSCVRCSGDNGCSTCQKKLFLLIWREGIRQYGACVHSCPPGYFGVRGQEVNRCTKCKTsYCETCFSKDFCMRCKEGFY 114 coelacanth
XP_008117010  36 C-TGCIMCSEDNGCISCQQKLFLIIWRDGMRQYGACVHACPPGYFGVRGQEVNRCIKCRSpNCESCFSKDFCIKCKQQFY 114 green anole
NP_001121500  39 caKGCDLCSEFNGCMKCLPKLFILLERNDIRQTGICLQSCPQGYFDDRNRENNRCLKCKInNCETCFSKNFCTKCKEGFY 118 tropical clawed...
XP_007656158  34 Q-GGCATCSDYNGCLSCKPRLFFVLERIGMKQIGVCLSSCPSGYFGTRYPDINKCTKCKAe-CETCFTRTFCTKCKNGYY 111 platypus
NP_001123245  42 Q-GGCATCSDYNGCLTCKPQLFFALVRNGMKQIGVCRPSCPNGYFGIRSPEINKCTKCKAd-CETCFNKNFCTKCKSGFY 119 tropical clawed...
XP_011603719  44 Q-GGCLTCSDYNGCLSCKPRFFMHLERIGMKQIGVCVTSCPPGFYGTRFPERSPCTKCRS-ECDSCFAKNFCTRCRAGFY 121 torafugu

4C8V_A        88 SHKGQCFEECPEGFAPLDDTMVC--Vd---G 113 tropical clawed frog
Q2I0M5       113 LYKGKCLPTCPPGTLAHQNTREC--Qg---E 138 human
EHA97268     113 LHKGKCLPTCPPGTLTHQSTREC--Qe---E 138 naked mole-rat
XP_008118101 166 LHKGRCY-NCTKDFSAANSTVEC--Nsp-aQ 192 green anole
XP_014348294 115 LFKGKCLISCPEGTAPDQQQREC--Fe---E 140 coelacanth
XP_008117010 115 LHKGKCLSTCPLDTIAQPSTQEC--LskpeK 143 green anole
NP_001121500 119 SHKGSCYSSCPEGFSAVNGTAECs-Sv---Q 145 tropical clawed frog
XP_007656158 112 IHMGKCLDSCPEGLETNNHTMECtsVv---H 139 platypus
NP_001123245 120 KHNGKCLDTCPEGFE-NNHNMECtsVv---H 146 tropical clawed frog
XP_011603719 122 LHLGKCQETCPEGLVRNEAQREC--Apkcpa 150 torafugu
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