Conserved Protein Domain Family
DUF4685
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pfam15737: DUF4685 (this model, PSSM-Id:374064 is obsolete and has been replaced by 464834)
Domain of unknown function (DUF4685)
This domain family is found in eukaryotes, and is typically between 106 and 131 amino acids in length. There are two conserved sequence motifs: SGE and VRF.
Links
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Statistics
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PSSM-Id: 374064
Aligned: 19 rows
Threshold Bit Score: 111.044
Created: 26-Apr-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
Download Cn3D
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EHB09817      275 RTFGPKPEAVLSTRHEEAKHLLQHPRMKARTRPLRASHDIVPA--------------------IAQGS-R-DGR----RS 328  naked mole-rat
EHA99933       71 CQFLPDLQDQLSGFQERLEKILHQ--RTSSLGQLSGDHSQFPT--------------------VRKAS-----S----FC 119  naked mole-rat
XP_014341089  362 RAFVSSEEPTLSPRHEQAKRLLERARMKARSSPLKADHSILPL--------------------KKDCC----PR----QS 413  coelacanth
XP_012663666  191 RSFLPDLWAQSAYFEDNLKNILLH--QXSTLGPLKGDHSQLTTlthqrrslvqdhtasldlvdVVSGS-S-SPY----SA 262  small-eared g...
XP_023357582  331 RAFVPSQELLLSPRNEQAQRLLQQARMKARTSPLRASHDIVPA--------------------VAVRLpGrDAG----CG 386  Tasmanian devil
XP_007480966  322 RALVSSQQLSLSPRHEQANQLLQQARMKAKTSPLRANHDIVPS--------------------MAH---R-LPArdvsSG 377  gray short-ta...
XP_008697107  105 CSFLPDLRGQSSYFQNSLKKILLH--QIPTLGTLRRDHSQF-T--------------------LKKAN-H-RPH----GA 155  polar bear
XP_015329169  198 SHFLPELGGQSSYLKNSLKKILLH--QIPALGPLSRDYPQFTT--------------------V-KAN-Q--PQ----AT 247  cattle
XP_009002416   49 RSFLPDLWGQSPHLQDSLTKILLQ--QTPALGSLKADRPQFST--------------------VRKAS------------ 94   white-tufted-...
XP_007664167   19 RACVPSQELVLSPQSEQAKQLLQRGRMKARTGPLRASHDILPA--------------------SVPHQ-R-FAG----GD 72   platypus

EHB09817      329 PALGPRMTLACRDS--PQSGSLSDSSSGESGSGQWPKQGMSTSHVRFEDEPAFEAEFRHLKRLQQRQRQVLST 399  naked mole-rat
EHA99933      120 GTPAPEAM-------------PTPTPSGE---GLGPRRHSCPFQVRLADEMLTDSALCYWEHSCAVQQSRMSp 176  naked mole-rat
XP_014341089  414 HGSGVHAVKKTRNEspPLSGNLSDSSSGESNCGLQKKRGQSPTRVRFEDESARDAEVRYWEREQQRKKGTLDl 486  coelacanth
XP_012663666  263 QIPKPKAV-------------VTRNLSGE---ASRARRRCSPLRVRFADETVRDTALRYWERSCAVRQRFTEN 319  small-eared galago
XP_023357582  387 VGQNPRLTLASQDGdaPYGGSLSDSSSGESSCGQRRKRGPSPSRVRFEDESAQDAEVRYRERSQQPPRRALDS 459  Tasmanian devil
XP_007480966  378 TIQTPRVTLACREGdvPYSGSLSDSSSGDSINDQRRKRGLSPSRVRFEDESAQDAEVRYRERLQQPQKRALDS 450  gray short-tailed op...
XP_008697107  156 QAPKLKAV-------------LTHSSSGE---SSGQRRRGCPFRVRFADETLRDTALRYWERSCAVRQGTIEN 212  polar bear
XP_015329169  248 QAPKLKAV-------------LTHNSSGE---GSGHRRRCCPFRVRFADETLRDTALRYWERSCAARQGIFEN 304  cattle
XP_009002416   95 -----------------------HRPSGK---GSGPHRPRCPFRVRFADETLQDTLLRYWERQCSVTQSVTVN 141  white-tufted-ear mar...
XP_007664167   73 PAPEPRMTSAPRDGdgSHGGNLSDSSSGESGCGQPRKRGLSPSRVRFEDESTRDAEVRYLDRMQQRQRRMLDS 145  platypus
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