Conserved Protein Domain Family
Cnd1_N
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pfam12922: Cnd1_N (this model, PSSM-Id:372385 is obsolete and has been replaced by 463750)
non-SMC mitotic condensation complex subunit 1, N-term
The three non-SMC (structural maintenance of chromosomes) subunits of the mitotic condensation complex are Cnd1-3. The whole complex is essential for viability and the condensing of chromosomes in mitosis. This is the conserved N-terminus of the subunit 1.
Links
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Statistics
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PSSM-Id: 372385
Aligned: 140 rows
Threshold Bit Score: 98.4067
Created: 1-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EGG23508              77 KDIRNIVLKIIQGGLQGLSIAI--QKVISitpqqqtDDhdrYNNQLLQVRSALKIYVYFLHILVKTQLERSPPEAADGAQ 154  Cavend...
ETN65880              69 GTQLIRAYDQLYGAIDNLGKSL--AEMLSq------KEi--DQADRLACLNAVKMLAFLMNGLVKAIDAHVNSNSDKMPK 138  Anophe...
WGS:AAQB:GK22013-PA   77 IQNLMRAFDLLYLTVDKLGEKL--SPLLAt------TEp-pSAQERGQYLNLTKMTIYLMVNTVKRIDKVVHQTLKDQQM 147  Drosop...
WGS:AANI:GJ20553-PA   77 IRNLMRAFDLLYLTVDRLGGQL--MPLLTs------SEp-pSSQDRVRYLNLTKMTLYLFVNVVKRIDVVVQQVMRD--- 144  Drosop...
WGS:AAPP:GF22385-PA   77 VRNLMRSFDLIYITVDKLGQDL--QPLLTg------AEp-mSNHVRSSYLNLTKMVLFLQVSTVKKLDQIVQQTLRDQQI 147  Drosop...
Q9VAJ1                77 AQNLMRSFDLLYLTVEKLFQDL--QPLLTa------SEp-mSNQQRNSYLNLTKMTLFLQVSTVKKINNSVQQAMRDQQL 147  fruit fly
EDW28938              78 LRNLMRSFDLLYMTVEMLGQSL--TETFAd------KE---PPTNRIRHLNLTKMTLYLQVNVVKKIDSVAQRAKRDQQM 146  Drosop...
EEB13176              73 QNVKDKGWKILKKSFNILVKSL--ENLFEd------VSc-iDSELQWKMCNITKMIVYTVIEFMKIHQDENIKQSNKVL- 142  human ...
18_pfamImport          1 FAQLQDVYDSVISRMLKDIGSFvrEAILN-------ED----PDSKREAVNVIKMNVYIFSIFEKAYEDKLSFNSENFIS 69  
XP_012550994          79 FDHIIRAAKNLCSHLELILQ----EQELD-------------VDVRVKNLNITKMIMYLFTQIMKTKDTKLAADNSTKLT 141  domest...

EGG23508             155 SssqtpakQGAKRKk-kGSSAAEEELW-DSDQNRERLIQYLYEAFEKDLTRLWPMTRPDEEMLSLVQRVLFSMLE-KQEN 231  Cavend...
ETN65880             139 --------KGKKQM------NDQAEAL-DWDEKRYQCIVQMYNLMQLPLEKLWDPPVCEESFVDIVCDICYRTLE--QQY 201  Anophe...
WGS:AAQB:GK22013-PA  148 Nq-----qKKRGKQ------PDTLEKYpDWDVRRGKFLVQLYNILQCPLEMLWSPPVAEESFVTMLCDICYRTLEvVTPR 216  Drosop...
WGS:AANI:GJ20553-PA  145 --------QQLNQQkkrAKQGEVLEQYpDWDVKRGKFLVQLYNVLQCPLEKLWNPPVAEESFVTMLCDICYRTLElVPPR 216  Drosop...
WGS:AAPP:GF22385-PA  148 Hv------QKKRAK-----QQEIMEQFpDWDHKRGKFLIQLFNVLQCPLEKLWSPPVAEEDFVSMFCDICYRTLElQPLR 216  Drosop...
Q9VAJ1               148 Nv------QKKRAK-----PSEGLEQFpNWEVKRGKFLVQLFNVLQCPLEKLWSPPVAEEDFINLLCDPCYRTIElLPLR 216  fruit fly
EDW28938             147 Nl-----qKKRGKQ------PEALDQYpDWDEKRGKFLVQLFNILQLPLERLWAPPIAEEDFITMLCDICYRTLElTPMR 215  Drosop...
EEB13176             143 --------EGKPRKk-lNKVINEESDW---AEEKRLILIEMHSFLLLPLKLLWEPPVVDEDFVNLIGNFCYNCLE-DPMI 209  human ...
18_pfamImport         70 Ep-----kRSKGLKt-kTKSVKPEDLW-DWNLQKKLAFTYIYEMLQQKLNLLWPSYVVEEALINLIANCCYKAFE-NPDV 141 
XP_012550994         142 ----------LGKKgkkATEEEELCGW--TESDKQAAMLTLYLVTQQPLSRLWDPPLAEDNFVSMIADPCYKALE--EQM 207  domest...

EGG23508             232 --IKTASIRISIYSFIVLLVKNYEFHMTT 258  Cavenderia fasciculata
ETN65880             202 --ARIRGTADSVFQILGTAIKRYNHSLSF 228  Anopheles darlingi
WGS:AAQB:GK22013-PA  217 --ADNRHVIDTVFQIFGTAIKRYNHAMTF 243  Drosophila willistoni
WGS:AANI:GJ20553-PA  217 --PDNRHIIDTIFQIFGIAIKRYNHAITF 243  Drosophila virilis
WGS:AAPP:GF22385-PA  217 --SDNRHIFDTVFQILGTCIKRFNQAMTF 243  Drosophila ananassae
Q9VAJ1               217 --MDNKHVFDTIFQILGTSIKRFNQAMTF 243  fruit fly
EDW28938             216 --HDNRHVFDTLFQILGTCIKRFNHAMTF 242  Drosophila persimilis
EEB13176             210 nsVNAKSIKETIFQILGVLINNYLHGLSF 238  human body louse
18_pfamImport        142 gqAKLKPLRDSVSQVLAVLVASYNHGITC 170 
XP_012550994         208 --IKNKAIRDTVFQVLGVLIKKYNHGTSC 234  domestic silkworm
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