Conserved Protein Domain Family
Angiomotin_C
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pfam12240: Angiomotin_C (this model, PSSM-Id:371984 is obsolete and has been replaced by 463503)
Angiomotin C terminal
This domain family is found in eukaryotes, and is typically between 197 and 211 amino acids in length. This family is the C terminal region of angiomotin. Angiomotin regulates the action of angiogenesis inhibitor angiostatin. The C terminal region of angiomotin appears to be involved in directing the protein chemotactically.
Links
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Statistics
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PSSM-Id: 371984
Aligned: 18 rows
Threshold Bit Score: 217.32
Created: 1-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
ELV13542      677 YVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRT-QQKHGNGQPAS--M-PEYNAPALMELVREKEERILAL 752  Chinese tree ...
XP_009289694  603 YVERVERLQQALAQLQVACEKREQLEQRLRIRLEREVDSLRT-QQRAGISVSRT--A-GESTAPAVLDLLREREERILGL 678  zebrafish
XP_005171265  424 YVEKVERLQGALTQLQATCEKREGLEMRLRTRLEQELRSLRN-QQRQPQPVG----GtSHVSVYTLQENLREKEERILSL 498  zebrafish
XP_015216789  432 YVEKVERLQHALSQLQAACEKREKLEQRLRTRLEQELKMLRA-QQRQTHGPGSA--SpSELSACALLERLREKEERILAL 508  spotted gar
CAG07655      535 YVEKVERLQSALAQLQSTCEKRESLEMKLRNRLEQELRSLRA-QQRQSQPPG--------VTLSSLQERLREREERILAL 605  spotted green...
XP_022534926  569 YVERVERLQLALGQLQAACEKREQLEKRLRTRLERELEALRT-QQRAGMGMALP--AvCESSAPALLDLLREREERILGL 645  Mexican tetra
XP_015197194  551 YVEKVEKLQQALSQLQAACEKREQLEKRLRTRLERELESLRT-QQRQGGAQAVP--P-SEYNAPALMELLREKEERILAL 626  spotted gar
XP_007244524  628 YVEKVERMQQALAQLQAACEKREQLEHRLRTRLERELESLRM-QQRQGGQQNPV--G-PEYSTTALMEHLREKEERILAL 703  Mexican tetra
XP_012811936  512 YVEEVEKLQQALTQLQAAGEKREQLEMRLRTRLERELESLRM-HQRQTNCQTSS--N-PEYNTPMLMDLLRKKEETILAL 587  tropical claw...
XP_005740349  651 yvekvermqqalaqlqaacEKREQLEHRLRTRLERELESLRMqQ-RQGGAQTSGviS-SEYNTTALMEHLREKEERILAL 728  Pundamilia ny...

ELV13542      753 EADMTKWEQKYLEESTIRHFAMNAAATAAAERD--TTIINHSRNGSYgESSLeahLWQEEEEVVQANRRCQDMEYTIKNL 830  Chinese tree ...
XP_009289694  679 EADMTRWEQKYLEESAMRHFAMEAAATAAAQRD--TTIIQHSRSGSYsDSSL---WLHEEENRIHSARQSQEMEQRIKDL 753  zebrafish
XP_005171265  499 EADKIRWEQKYLEEKTMREFAMDAAATAAAQRD--TTIINHSPCHSF------------IEELPSTEYRNQEVENRIRSL 564  zebrafish
XP_015216789  509 EADMTKWEQKYLEESTMRQFAMDAAATAAAQRD--TTIINHSPRHSP-NNSF-------NEDLLTANHRHQEMENRIRAL 578  spotted gar
CAG07655      606 EADMVRWEQKYLEESTMRQFAMEVAATAAAQRD--TTIINHSPCHSS-NNSF-------NEDLPVADYRNQEMENRIRAL 675  spotted green...
XP_022534926  646 EADMMCWEQKYLEESAMRQFAMEAAATAAAQRD--TTIIQHSRSGSYsDGCL----WQHDGEDKTHNRQCQDIETRMKDL 719  Mexican tetra
XP_015197194  627 EADMTKWEQKYLEESAMRHFAMDAAATAAAQRD--TTIINHSRNGSYsDSSLearIWQEEEEILQANRRCQDMEHRIKNL 704  spotted gar
XP_007244524  704 EADMTKWEQKYLEESVMRQFALDAAASVATQRDtsTAIISHSPSSSY-DTSVearIQKEEEEILMANRRCLDMESRIKNL 782  Mexican tetra
XP_012811936  588 EADMTKWEQKYLEESAMRHFAMDAAATAAAQRD--TTIINHSRNGSHnDNSLevrSWQEDEEIIQANRKFQDMEHTIKNL 665  tropical claw...
XP_005740349  729 EADMTKWEQKYLEESVMRQFALDAAASVATQRDtsATMISHSPSSSY-DTSVearIQKEEEEILMANRRCLDMESRIKNL 807  Pundamilia ny...

ELV13542      831 HAKIIEKDAMIKVLQQRSRKDAGkad------------ssSLRPARSVPSIAA------ATGTHSRQ 879  Chinese tree shrew
XP_009289694  754 HAQLLEKDAMIKVLQQRSRRDPA-----------------PLRPARSVPSISA------ATGLHARQ 797  zebrafish
XP_005171265  565 YAQILEKDTVISILKQKLQHEQkgq-------------lgALQPATADSSIISs----hSTPAHTAQ 614  zebrafish
XP_015216789  579 HAQLLEKDAVIKVLQHRSRRDPSkge------------qqGLRPAKSVPSITA------AASAHSWH 627  spotted gar
CAG07655      676 YAQILEKDAVIKILNQRLHQDQGrkdeqtphanllnkaaaSLRPATSTPSISTt----tTTKTRVKS 738  spotted green pufferfish
XP_022534926  720 HAQLLEKDAMIKVLQQRSRRDST-----------------PLRPARSTPSITV------ATGLHSRQ 763  Mexican tetra
XP_015197194  705 HAQIIEKDAMIKVLQQRSRKEPGktd------------avLLRPARSVPSISV------ATGLHLRQ 753  spotted gar
XP_007244524  783 HAQIIEKDAMIKVLHQRSRKEPGskgd----------gpsTMRPSKSLMSIATgtggssGSGLLSHS 839  Mexican tetra
XP_012811936  666 HAKIIEQDAMIKVLHQRSRKDPGknd------------ssSLRPARSVPSIAAvtlsntSTGVHSRQ 720  tropical clawed frog
XP_005740349  808 HAQIIEKDAMIKVLHQRSRKEPVksd-----------apsAMRPSKSLMSISNt----gGSGLLSHN 859  Pundamilia nyererei
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