4ZI2,2K0S


Conserved Protein Domain Family
ARL2_Bind_BART
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pfam11527: ARL2_Bind_BART (this model, PSSM-Id:371583 is obsolete and has been replaced by 463288)
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The ARF-like 2 binding protein BART
BART binds specifically to ARL2.GTP with a high affinity however it does not bind to ARL2.GDP. It is thought that this specific interaction is due to BART being the first identified ARL2-specific effector. The function is not completely characterized. BART is predominantly cytosolic but can also be found to be associated with mitochondria. BART is also involved in binding to the adenine nucleotide transporter ANT1.
Links
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Statistics
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PSSM-Id: 371583
Aligned: 97 rows
Threshold Bit Score: 69.5275
Created: 2-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4ZI2_C            17 SIAGFLRGPDWSIPILDFVEQKC---------EVF-------DDe-------EESKLTYTEIHQEYKELVEKLLES-YLK 72  house mouse
CBJ30390          45 ALEEAVMDPAFASLQQVFVDEWCgayipqqllREF-------EDv-------EENRLIYTDLFRQYTRLVERHLDGwLRQ 110 Ectocarpus ...
EFJ46363          73 ALEDVLMDPEFEELREGFCRENC---------HHF-------EDt-------DENKLIYTDIFTKYTELVESTIDQkLKQ 129 Volvox cart...
EEH56095          80 ALEELLASEAFAAAQSAFLRRHC---------DVF-------EDt-------EENKLEYTTLFDEYTSALEDAMETsLGA 136 Micromonas ...
jgi:MICPUN_61197  65 ALEDLLMSDGFSERQAEFCRAKC---------HVF-------EDt-------EENKLEYTSIFDEYTETLEAAMMGhLDE 121 Micromonas ...
17_pfamImport      8 ALQDILIDPEFVALQSDFCFRNC---------EVF-------ENv-------TENKLIYTSIFNEYANLIESFLEQrLLE 64 
15_pfamImport      7 VIAYFFDDEAFAATFEQFAEANC---------LAF-------DIe------sDEMKLEYTAIYNKFLALFESKLED-YIV 63 
18_pfamImport      4 RAAEHCVTSKFEHIFDNFARENA---------EVF-------MDaveakggdVEHKHEYKELHDRYLRLFEEELSD-FIE 66 
EEY59137          12 ALAEYIKTPQFQCQFEQFFLDHA---------LTF-------TDa-------LEHQLAYMTIYVEFQHMFNEHMKI-FLT 67  Phytophthor...
KUF67212           6 raAEFCSSPKFERVFDNFARDHA---------DAFidateakDGd-------VEHKHEYKELHDQYLKLFEEELSE-FVE 68  Phytophthor...

4ZI2_C            73 EI-GINEDQFQEAC--------TSPLAKT---RTSQAIL--QPVLAAEDFTIFKAMMVQKNIE 121 house mouse
CBJ30390         111 RIrGFEMETFMKMV-----------AERQg--EVVDDVS--DILMAVGDFAEFKGMMVAHRKG 158 Ectocarpus siliculosus
EFJ46363         130 AVpGFSMQEFMLLL-----------ESHKd--HLMSEVF--ELLLSLADFEAFKEVMLSYKRD 177 Volvox carteri f. nagariensis
EEH56095         137 AVeGFDMAEFAEML-----------AKREgtgELDGDAF--DLLMTLSSFDAFKELMLAYKAE 186 Micromonas pusilla CCMP1545
jgi:MICPUN_61197 122 SVeGFDAAEFFDML-----------EQREg--QLDGDVF--DLLMTLTSFEAFKELMLDYKRE 169 Micromonas commoda
17_pfamImport     65 KLeYFSMDELVRQM-----------QEHEd--EIPLDVI--DVLQSCFDFEEFKSLMLSFK-- 110
15_pfamImport     64 SQ-GATVKQFYDLVrea--------yaTN---RESSIVLcsEILVATADFDVFVMMMKQTKES 114
18_pfamImport     67 SE-GATIEEFFRECrdimegnyTALFSDE---HQYKWFV--EHLVASMDYNQFYALMVNEARR 123
EEY59137          68 QQ-GVTEDEFAEHC--------QKAMKVD---PKVEQYL--EIVIASMDYDAFIGLMKSMRAR 116 Phytophthora infestans T30-4
KUF67212          69 SE-GATIEDFFKECreir-dgqFTALFEE---HTYAWFV--DHLLACMDYKHFYGLMVNEARR 124 Phytophthora nicotianae
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