5SVA


Conserved Protein Domain Family
Med21
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pfam11221: Med21 (this model, PSSM-Id:371423 is obsolete and has been replaced by 463241)
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Subunit 21 of Mediator complex
Med21 has been known as Srb7 in yeasts, hSrb7 in humans and Trap 19 in Drosophila. The heterodimer of the two subunits Med7 and Med21 appears to act as a hinge between the middle and the tail regions of Mediator.
Links
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Statistics
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PSSM-Id: 371423
Aligned: 88 rows
Threshold Bit Score: 81.8604
Created: 2-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5SVA_W         1 MTDRLTQLQICLDQ---MTEQFCATLNYIDKNHGFERLTVNEPqmsdk----------------------hatvvPPEEF 55  baker's yeast
EFJ52925       2 sSDLLTELQRQLRD---VNDQFAIVIEQLIHIAPPAPLEGDSGqivaeep----------------------savshaEL 56  Volvox carteri ...
ESS28669       8 aADPVTRLQQLLTN---FSRHLYDVVQQVPELAPPLPLSPTDSssssassss--------------aspasgeaeKRSQV 70  Toxoplasma gond...
XP_004348835  71 T-DRLTQLQDRISQ---MAEMLFTSVGVLKDFRPTDAASQTATilpagap--------------------apsgmsLQQY 126 Capsaspora owcz...
EGD82560       1 MGDRVTQLQELLQA---LMEHYRNAVGVLHMQAGEAAME-PAPssakkqpqkqpqk-------qqnngeegavasARQQV 69  Salpingoeca ros...
EDV20187       1 MADRLSQLQDAVNQ---LAQHLCDSVGVLQQSAPLSYFDefeshdrgllsiqwmqtnqilysntvsylavhnpttNGENV 77  Trichoplax adha...
CBY42024       1 MSDRLSQLQDFVND---LAIHMCNSIGVLHESAPTSSFDDAETrtttprp------------------daaefgaQKTES 59  Oikopleura dioica
CDS38069       1 MADRLTELQDAINL---QAENLGNAVGVIQQLAQPSLFRelnhngrreke--------------wasnpefqallQSQSQ 63  Echinococcus mu...
EEB20248       1 MADRLTQLQDTINLnavQAENFCNSIGILQQFAQPGKFSGFERsgsqtpq-----------------------qgnqqaQ 57  human body louse
Q7PTL0         1 MADRLTQLQDTVNQ---QAEHFCNSIGILQQCSVPSKFAGFERtgsqtpqqqvhq--------qqqlpqqqqqqqQPQQQ 69  African malaria...

5SVA_W        56 SNTIDELSTDIILKTRQINKLIDSLPGVDVSAEEQLRKIDMLQKKLVEVEDEKIEAIKKK-EKLLRHVDSLIEDFVD 131 baker's yeast
EFJ52925      57 QVKALELSKGIAQRFKDINTIISKLPDAYEPPEKQDARIGVLLHEHHALRKELGLVMQEA-ERKLEEIHGCYEAIAQ 132 Volvox carteri f. ...
ESS28669      71 ESFLLRSANNVAAIMHAIETEIGNLPSSLRTREETQRRIAFLEKENDRAAKELQAVAAEA-TRVREALRQLLRhsit 146 Toxoplasma gondii VEG
XP_004348835 127 EEFAQTHASMIARTAKEIDVLIDSLPEMHVDAEDELQMFANLHKQNADAGIAFGETVNLA-EAHLTAVKQALHFVAs 202 Capsaspora owczarz...
EGD82560      70 QQTVDVTKHAILQTVKDINLFCDHLPDIKQATNTNDDDLDELHRKNAEAASLLRTKVQLA-EERLALLRGRITDITN 145 Salpingoeca rosetta
EDV20187      78 ENNLDVFATLITRTAQDIDYIITSLPDIRVSQQNQEKAIERLQEENAQARQQLVEAITRA-EGVLLKVKQIKNQVAa 153 Trichoplax adhaerens
CBY42024      60 RRNIELFSSLITRTFKNIDTLIDSLPSEESTSSLQAATLQKIQTENQAEAERLRSFVEKG-EKIHDRIQAALDDIAD 135 Oikopleura dioica
CDS38069      64 EDNAHKFAVTIATTAKQIELLINSLPAEEASLELQDEVTRQLLSDYRKESAKLVHLITKSfQTRLSKVRQLLSKIAe 140 Echinococcus multi...
EEB20248      58 EDYAQLFATLIARCAKDIDVLIESLPNEDSSTELQVASLRRLETENQEAADRLEQVVKKG-ELLLEQIQSALADIAQ 133 human body louse
Q7PTL0        70 EDFPQLFSTLISRCAKDIDTLIESLPSEESSIELQVQSLQRLEAENKESAEKLEEIVRKG-ELLLEKIQAALSDIAQ 145 African malaria mo...
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