pfam10524: NfI_DNAbd_pre-N (this model, PSSM-Id:371114 is obsolete and has been replaced by 463134)
Nuclear factor I protein pre-N-terminus
The Nuclear factor I (NFI) family of site-specific DNA-binding proteins (also known as CTF or CAAT box transcription factor) functions both in viral DNA replication and in the regulation of gene expression in higher organisms. The N-terminal 200 residues contains the DNA-binding and dimerization domain, but also has an 8-47 residue highly conserved region 5' of this, whose function is not known. Deletion of the N-terminal 200 amino acids removes the DNA-binding activity, dimerization-ability and the stimulation of adenovirus DNA replication.
Jiyao W et al.(2023). "The conserved domain database in 2023.",