2CAZ


Conserved Protein Domain Family
Vps23_core
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pfam09454: Vps23_core (this model, PSSM-Id:370504 is obsolete and has been replaced by 462803)
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Vps23 core domain
ESCRT complexes form the main machinery driving protein sorting from endosomes to lysosomes. The core domain of the Vps23 subunit of the heterotrimeric ESCRT-I complex is a helical hairpin sandwiched in a fan-like formation between two other helical hairpins from Vps28 (pfam03997) and Vps37. Vps23 gives ESCRT-I complex its stability.
Links
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Statistics
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PSSM-Id: 370504
Aligned: 118 rows
Threshold Bit Score: 53.619
Created: 3-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2CAZ_A                         13 SIAVAKTDGLNQLYNLVAQDYALTDTIECLSRMLH--RGTIP---LDTFVKQGRELARQQFLVRW 72  baker's yeast
EGV60318                      412 EVVISDSVLTNQLYEISSEIKANNDCMSLIGGSFDneNELIDdasFDTCVKTVRGIGRDIFWLKL 476 Yamadazyma te...
CBZ05870                      268 NCLVPADPLQARALELLAEIHAADDTLALLEEGLK--RELMT---CDEYVKNVSDVGREQFVSRH 327 Leishmania ma...
Q382B4                        312 DCIVPADEVHARALELLGDIHSLDDVLELLERSLR--HGQIT---CEEYVRRVSDVGRQQFEARF 371 Trypanosoma b...
A0BPW4                        218 lqhisTTPYQDQLIELDAKIKGIRDTLRLIQHNFQ--NNHLN---FLELNQFTRNLAKEEFDAFL 277 Paramecium te...
A0BV93                        339 qniRENDQFSTSILELYSDIQACRETLHFIVTKFK--NFNLP---FETVIKMTRKYSEEQFNNIL 398 Paramecium te...
A0CR15                        375 eelmQTDPLSNQIIDLTSEIQAQKEGLYYVQKKFR--HQNLD---YDQLIKITRQMSQQMFDQYL 434 Paramecium te...
WGS:AAGF:cds.TTHERM_00486330A 261 kyMTAQSPVHNQILQLIAELDAIKETFLFTDEWFK--RSK-D---FDQYSSQIKLLAEREFECKI 319 Tetrahymena t...
Q24HU3                        343 NFIKEQNPLQNQILELTSEQEAIKETIIYIEEAFK--QKKID---FETLIKSIQYYSELEFNTKL 402 Tetrahymena t...
CCD13374                      314 kCIVPADDLQAHALELLGEIHASDDVLELLERSLR--EGQIA---CEEYIRRVMDVGRQQFESRF 373 Trypanosoma c...
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