3JBR


Conserved Protein Domain Family
VWA_N
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pfam08399: VWA_N (this model, PSSM-Id:369855 is obsolete and has been replaced by 462464)
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VWA N-terminal
This domain is found at the N-terminus of proteins containing von Willebrand factor type A (VWA, pfam00092) and Cache (pfam02743) domains. It has been found in vertebrates, Drosophila and C. elegans but has not yet been identified in other eukaryotes. It is probably involved in the function of some voltage-dependent calcium channel subunits.
Links
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Statistics
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PSSM-Id: 369855
Aligned: 53 rows
Threshold Bit Score: 80.0222
Created: 3-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3JBR_F               109 VQAAHQWREDFAsNEVVYYNAKDD-----LDPEKND--SEPGs-------------QRIKPVFIDDANFR-RQVSYQHAA 167  rabbit
CDS28666              54 IEEEFKLQESLD-HDECYIRAKAVslfphLPDENGTviTPCN--------------ESQFLPLESDPMFGnFYISRNMSA 118  Hymeno...
EHB12295              83 IREKFNRYLDVVsRNKQVVEASYT-----------------------------------------------AHLTSPLTA 115  naked ...
EEB14544              78 SSQNEILE------NFQYYNAKCLimddd-----------------------pctnDSLKADLLPNSHFWdLEVNTSFSA 128  human ...
20_pfamImport          4 AAMASQDEGNVP-LDYQYYNAKTMevtvk----------------------gvdppNSSRLLLTPNSNFFnIAINTNVSA 60  
Q7Q758                74 TAISFDEEPVNQ--SFQYYNAKQM-------IEPGEiiTTPIpmidedpadittpiPPKEIVLTKKRHFFnEAVNTTVSS 144  Anophe...
19_pfamImport          2 IAKDHHNEKPQT--NLSYYNAKEM-------LEPGEtpPPPLtfdidfagipplniTPMTIVLTPTPEFFdEPINTSVSS 72  
WGS:AAPP:GF13711-PA  113 TALSHQNDLADK--MFSYYNAKEMl----EPGDPFPpiPTPApdmdkdigepliyvQPKVVVLEKRPEFHnTPVNFSVSS 186  Drosop...
XP_028034480         109 MAFDKQNEPVPE--DFQFYNSKEMd----EPYDDVSltTTPEpefnvd--nwivrpPTKSAHLQSNPHFSnIPVNANFSS 180  wild s...
XP_015790974         142 AEKAAEMASEDNyNDFSYINSKRLydvteVNYKDASpdGRDY-----------------SLLLTPQSVFRnVPVYDKKSA 204  two-sp...

3JBR_F               168 VH----IPTDIYE-------------GSTIV----------LNELNWTSALDDVFKKNREEDPSLLWQVFGSATGLA-RY 219  rabbit
CDS28666             119 AH----VPTNVYD-------------LSKEI----------RTVGNLTHHLDEVFKKNLKEDPLLKWQYFCSSTGFL-KF 170  Hymeno...
EHB12295             116 IQdcctIPPSMMEpvqsrfgvlspkcGARTVpvytlavlviVCGRVPVQELRLVLADNLKSNPGIKWQYFSSEEGIF-TV 194  naked ...
EEB14544             129 VH----VPTNVYD-------------RATDV----------LKAIRWSENLNDIFKNNYQIDPSLTWQYFGSSTGFM-RQ 180  human ...
20_pfamImport         61 VH----VPTNVYD-------------RAPDV----------LHGIEWSSNLNEIFISWFNNHEAITFLIITDSNNVLaHY 113 
Q7Q758               145 VH----VPTNVYD-------------RATEV----------IKAIKWSEALDSIFYNNYIGDPTLTWQYFGSSSGFL-RQ 196  Anophe...
19_pfamImport         73 VH----VPTNVFD-------------RAPEV----------IQAIEWSEKLDAIFKNNYKEDPTLSWQFFGSAFGFM-RQ 124 
WGS:AAPP:GF13711-PA  187 VH----VPVNVFD-------------RAPDV----------IKAIQWSENLDQIFRDNYKNDPTLSWQFFGSSTGFM-RQ 238  Drosop...
XP_028034480         181 VH----VPTNVYA-------------WAPEV----------IKGIHWSEGLDTHFINNYQSDPTLSWQYFGSSTGFM-RH 232  wild s...
XP_015790974         205 VH----IPTNVFE-------------DKQDL----------KEAIKWSEKLDAQFDYNHVNDSEVNWQFFCSSKGFL-RF 256  two-sp...

3JBR_F               220 YPASPW 225  rabbit
CDS28666             171 YPGAMW 176  Hymenolepis microstoma
EHB12295             195 FPAHKF 200  naked mole-rat
EEB14544             181 FPAIQW 186  human body louse
20_pfamImport        114 FLAMKW 119 
Q7Q758               197 FPATKW 202  Anopheles gambiae str. PEST
19_pfamImport        125 YPSSKW 130 
WGS:AAPP:GF13711-PA  239 FPASKW 244  Drosophila ananassae
XP_028034480         233 YPGkil 238  wild silkworm
XP_015790974         257 FPASKW 262  two-spotted spider mite
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