Conserved Protein Domain Family
NPP

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pfam08384: NPP (this model, PSSM-Id:369844 is obsolete and has been replaced by 429962)
Pro-opiomelanocortin, N-terminal region
This family features the N-terminal peptide of pro-opiomelanocortin (NPP). It is thought to represent an important pituitary peptide, given its high yield from pituitary glands, and exhibits a potent in vitro aldosterone-stimulating activity.
Statistics
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PSSM-Id: 369844
Aligned: 18 rows
Threshold Bit Score: 70.0756
Created: 3-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003227954  28 CLDGGWCQDMATEADLMECLRACRDSLSLsdETPIYPGHGHMKPL 72  green anole
XP_006002164  27 CWESSRCRDLSTEANVLECISACKADLSA--ESPVYPGNGHMQPL 69  coelacanth
EHH55419      28 CLESSQCQDLTTESNLLECIRACKPDLSA--ETPVFPGNGDEQPL 70  crab-eating macaque
Q7ZT18        30 CWENARCRDLSTEENILECIQLCRSELTD--ETPVYPGESHLQPP 72  zebrafish
PWA32778      23 CWESLSCQELNSESSMMDCIHACRSDLTA--ETPLVPGDAHLSPP 65  western mosquitofish
XP_006626112  24 CWEHSQCRDLSSEENILECIQACKSDLTA--ESPIFPGNGHLQPP 66  spotted gar
XP_007244740  29 CWENGPCRDLSSEEQILDCMKSCKSNLKM--ESPLFPGEGHLQPL 71  Mexican tetra
XP_016082589 215 CSENGRCKDLSSEANVVECLRACKLDLSA--EAPVIPGNGHLEPL 257 platypus
XP_008253036  23 CLESSQCQELTTESHLLQCLRACQLDRSA--ETPVFPGNGDAHPL 65  rabbit
XP_005062814  24 CRENSKCRDLGSEAGILACAGSCRAQLSL--ESPLFPGNGQFQPL 66  collared flycatcher
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