Q7Q072        40 HRTRHSHrssSNNHSRsGSNNKrpdmapfQTSVNL-GDDGRDGQEIIEVSILP--------------------------- 91  Anopheles gambi...
EEN69483      26 RDRKRRSrgdHNHSSSlLKADR-------SVTIQTpPHSTTGGGDGEDGEE----------------------------- 69  Florida lancelet
CBY14823      31 dvSRATSrasRRSRRPhSSKDK-------SVSIKApQRSRQS--DSRRKED----------------------------- 72  Oikopleura dioica
Q4VBG5        24 RDRRERHr-sKSREGS--RGDK-------SVTIQApG-EPLLDNESTRGED----------------------------- 63  tropical clawed...
XP_019203550  24 RDRRDRHr-sKSRDSS-SRGDK-------SVTIQTpG-EPLLDAESTRGDD----------------------------- 64  Nile tilapia
XP_016159644  27 QGSRDRHkspRSKDGS--RSEK-------SVTIQTpPAEPLLGNDTSRAEE-G--------------------------- 69  collared flycat...
1_pfamImport   1 ERNRERHkspRSKDGR--GSEK-------AVTIQApTGEPLLGNDSTRTEE-V--------------------------- 43 
XP_007259108  25 ERSRDRHk-sRSKDSS--RSEK-------SVTINApPAEPLLGDQSMRGEE-M--------------------------- 66  Mexican tetra
AAI63391      26 RSSRDRHk-pHSRDSS-SRSDK-------NVTISAtSVQPQQPDQSSAPTD-A--------------------------- 68  zebrafish
XP_011608321  22 DRSRERHkasSSKDSS-RSER--------SVVINp-PDTPSQDSPVHNGEPLPgeprpaadhgedaqahfyrgeislifh 91  torafugu

Q7Q072        92 -----QDET------------WGDNTTAITGnTSEQS-ISMEDVSYFQMADDRGV-GFACQRYLERGLAVML--CAVAFV 150 Anopheles gambi...
EEN69483      70 ------DDN------------WGDNTTAITG-TSEQT--SMEDISRMAKDMEDSI-GLGSIQHLGVVIATML--SFFAFL 125 Florida lancelet
CBY14823      73 ------DDNagldaaaddsrrWPGETDTFA--TSECTrISNEDLGKFHADLGARL---NVTRYLNPALLSVVltQLFAYV 141 Oikopleura dioica
Q4VBG5        64 -----RDDN------------WGETTTVVTG-TSEHS-ISHDDITRITKDMEDSA-KLDCSRHLGVVIGGAL--ALLSFL 121 tropical clawed...
XP_019203550  65 -----RDDN------------WGETTTVVTG-TSEHS-ISNEDLTRVTKDLEEST-PLECKRFVGPALGGCL--SFFALV 122 Nile tilapia
XP_016159644  70 -----QDDN------------WGETTTAITG-TSEHS-ISQEDIARISKDLEDSV-GLDCKRYLGLTVAAVL--GLLVFL 127 collared flycat...
1_pfamImport  44 -----QDDN------------WGETTTAITG-TSEHS-ISQEDIARISKDLEDSV-GLDCKRYLGLTVAAAL--GLLVFL 101
XP_007259108  67 -----QDDN------------WGETTTAVTG-TSEHS-LSQEDIVRISKDLDDSV-GLDCKHYLSVSFSVIL--GLLVLL 124 Mexican tetra
AAI63391      69 -----QDDN------------WGETTTAVTG-TSDHS-LSQEDLAGFGKDTEGPVeKLNCIRFLPLALTLLL--GLLVLV 127 zebrafish
XP_011608321  92 lrtagKDDN------------WGETTTAVTG-TSELS-ISQEEVVGLGKEIQDRT-Q-GIRRYLPLAVGVCV--GLLVVA 153 torafugu

Q7Q072       151 SPLAMVVLPRVgffpaafesldlsqNERLRLL-ACNAECKGMLVSLAARLLLLAIGLWALFLRQPAAIMPRIFLFRSCAL 229 Anopheles gambi...
EEN69483     126 TPIAFVVLPLV--------------LWKETLD-PCNTVCHGLFISFAFKLLILLIGAWALFFRRPRVVMPRVFVFRSMIM 190 Florida lancelet
CBY14823     142 TPIFFLVLPKVl------------sESTPSLHdDCDIGCEGQIIAIAVRLFVLFLASLYLFWRTPRSKVPQINLYRTGVN 209 Oikopleura dioica
Q4VBG5       122 TPIAFMLLPQI--------------LWREDLE-QCGTACEGLFISVAFKLLILLLGSWALFFRRPKAFFPRVFVFRALLM 186 tropical clawed...
XP_019203550 123 TPLAFLILPQV--------------LWRDALE-PCGTPCEGLYVSLAFKLLVLLISSWALFLRPPRATLPRFFVFRCLLM 187 Nile tilapia
XP_016159644 128 TPIAFILLPQI--------------LWRDDLE-PCGTVCEGLFISVAFKLLILLIGTWALFFRQPKADLPRLFVFRALLL 192 collared flycat...
1_pfamImport 102 TPIAFILLPPI--------------LWRDQLE-PCGTICEGLFISVAFKLLILLIGTWALFFRKQRADLPRVFVFRALLL 166
XP_007259108 125 TPLAFLVLPHL--------------LWPERLR-VCGTACEGLFISVAFKLLILLLAVWALFFRPPRAGMPRIFVFRALLS 189 Mexican tetra
AAI63391     128 TPLSFLILPQL--------------MWPERLQ-TCGTACEGLFLSLAFKLLILLLAGWALFMRPTRASLPRIAVFRALLG 192 zebrafish
XP_011608321 154 TPLVFLLLPAV--------------LWPDRLQ-ACGAACEGLFLSISFKLLILLVAIWALFLRLGHASLPRVCVYRAFLT 218 torafugu

Q7Q072       230 LLVLISSFAYWLFYIVQVTEGAraivsgssVVDYRTLVAYATSFCDTLLFVHYVAVVLLEIRHLQPLYHVKVIRSPDGES 309 Anopheles gambi...
EEN69483     191 ALVFVYTLSYWLFYGVRVLDER--------PSNYQDIVQYAVSLVDALLFIHYLAVILIELRHLRPQFIVKVVRNTDGEN 262 Florida lancelet
CBY14823     210 FLTFLVTAVYWIFYSYKVIHWE--------DYEYPPIVKYSSNFVDILLFVHYLAIVLLFLRRDQEIYLLEVVRTTDGAQ 281 Oikopleura dioica
Q4VBG5       187 VLVFLLVVSYWLFYGVRILESR--------DKNYQGIVQYAVSLVDALLFVHYLAVVLLELRQLQPQFTVKVVRSTDGAS 258 tropical clawed...
XP_019203550 188 VLVFLFVASYWLFYGVRVLEPR--------ERDYRGIVEYAASLVDALLFIQYLALVLLEVRHLQPAFCLKVVRSTDGAS 259 Nile tilapia
XP_016159644 193 VLIFLFVFSYWLFYGVRILDLK--------DTNYQGIVQYAVSLVDALLFIHYLAIVLLELRQLQPMFTIKVVRSTDGES 264 collared flycat...
1_pfamImport 167 VLIFLFVVSYWLFYGVRILDSR--------DRNYQGIVQYAVSLVDALLFIHYLAIVLLELRQLQPVFSLQVVRSTDGES 238
XP_007259108 190 TLVFLFVLSYWLFYGVRIFDTK--------DEDYQGIVQYAVSLVDALLFIHYLAIVLLELRQLQPCFSLCVTRSTDGET 261 Mexican tetra
AAI63391     193 LLTLLLLLSYWLFFGVRILDSQ--------DDNYQGIVQFAVSLVDALLFIHYLAVVLLEIRHLQPCFSLCVVRSTDGET 264 zebrafish
XP_011608321 219 TLTLLLTMSYWLFYGVRILDAQ--------DEDYHGIVQFSASLVDSQLFVHYLAVVLLELRHLHPCYNVCVIRSTDGET 290 torafugu

Q7Q072       310 HSYSIGQLSIQRAAVWVLQRYYTEFSIYNPYLERLPvSKAQRKAAAvsSFKYYDV--DGATPAQ-----QQSQSRAVLAA 382 Anopheles gambi...
EEN69483     263 RFYHVGQFSIQRAAVWLLEQYYRDFPPYNPALMHIP--TRAPKQLT--GFKFYDV--DGNPGNA-----SASQTRAMIAA 331 Florida lancelet
CBY14823     282 RFYNIGNVSIQEAASWVLEKYYVDFHLYNPALQKSS-KSSKLKNVT--NFQVLNV--DGGGEES-----KNDRTRAILTA 351 Oikopleura dioica
Q4VBG5       259 RFYNIGHLSIQRVAVWILENYYHDFPVYNPALLNLP-KSILSKKMS--GFKVYSLgeENTTNN------STGQSRAVIAA 329 tropical clawed...
XP_019203550 260 KFYNVGHLSIQRAAVWVLDRYYSDFPVYNPALLNLP-KSILSKKMT--GFKVYSLd-ENTTNN------STGQSRAMIAA 329 Nile tilapia
XP_016159644 265 RYYSLGHLSIQRAALVVLENYYRDFTVYNPALLTAS-KSRAAKHMA--GLKVYNV--DGPGNN------ASGQSRAMIAA 333 collared flycat...
1_pfamImport 239 RFYSAGHLSIQRAALVVLENYYKDFTIYNPNLLTAS-KFRAAKHMA--GLKVYNV--DGPSNN------ATGQSRAMILS 307
XP_007259108 262 RHYNLGQLSIQRAAVAVLENYYRDFPVHNPALLTAS-KSRAAKHLA--GLKVYNV--DGPGGNNaaagiAQSQSRAMIAA 336 Mexican tetra
AAI63391     265 HHYNMGQLSIQRAALVILEHYYKDFTVHNPALLTAA-KSRAAKHLA--GLKVYNV--DGAGSDA-----ATAQSRAKMAA 334 zebrafish
XP_011608321 291 RHYNIGQLSIQKAALSILEYYYRDFPVHNPALLSAS-KHRAAKHLA--GLKVYNV--DGAQP-G-----NESQSRAMVTA 359 torafugu

Q7Q072       383 HARRRDSSHNERFYEEHE----YERRVKKRRARLVTAAEEAFTHIKRMQQpsspQQ-QhdqqgdgsgaapPAIPLDPQ-- 455 Anopheles gambi...
EEN69483     332 AGRRHESIHKERYYEEQE----YERRVKKRRVRFVCATEEAFTHIKRLSE----Er-------------gPAVPMDPH-- 388 Florida lancelet
CBY14823     352 AARRRDAGHNEKYYEEVE----RERRVRKRKARLTEAAEDAFSHVRRQLI----PD-Asl---------aGNDSMDPR-- 411 Oikopleura dioica
Q4VBG5       330 AARRRDNSHNEYYYEEAE----HERRVRKRKARLVVAVEEAFTHIKRLQD----ED-Qk----------nPREIMDPR-- 388 tropical clawed...
XP_019203550 330 AARRRDNSHNEYYYEEAE----MDRRIRKRKARLVVAVEEAFTHIKRLQE----EE-Aass------pkhPREVMDPR-- 392 Nile tilapia
XP_016159644 334 AARRRDSSHNELYYEEAD----HERRVKKRRARLVVAVEEAFTHIKRLQA----EE-Qqk---------aPGEMMDPR-- 393 collared flycat...
1_pfamImport 308 EADMSTRGTLGSCWYRPEglcsH------------TVL---YTHELLLVTfsltRD-Nlrk------advPGK--DHRca 363
XP_007259108 337 AARRRDTSHNELYYEEAE----HERRVRKRKARLVVAVEEAFTHIRRLQE----EE-Qkk---------sPGEIMDPR-- 396 Mexican tetra
AAI63391     335 AARQRDTSHNELYYEEAE----HDRRVRKRKARLVVAVEEAFTHVRRLQD----EE-Kkk---------pPGDEMDPR-- 394 zebrafish
XP_011608321 360 AAKRKDAAHSELYYEEAD----YERRVRKRRARLVVAVEEAFTHVRRMKK----EDeQa----------aPSDIMDVH-- 419 torafugu

Q7Q072       456 ---EAAQAIFPSMARALQKYLRVTRQQPRHTVESILKHLAHCLKHDMSPRAFLEPYLVEAPVLQNDKERRTNHNWALICD 532 Anopheles gambi...
EEN69483     389 ---EAAQAIFPAFARPMQKYLRVTKQQPYHTMDSILKHLAFCIVHDCTPKAFLERYLTPGPSIQNESEIHKKQKWTLVSD 465 Florida lancelet
CBY14823     412 ---QTAEIVFPSIARSMQKYLRTTRQNQHYTIEDIIDHLAFCIRYDMGANAFLNRYTEKRPPTAYPGQIMQSVDWSVTCD 488 Oikopleura dioica
Q4VBG5       389 ---EAAQAIFASMARAMQKYLRTTKQQPYHTMESILHHLEFCITHDMTPKAFLERYLGPGPTIQYHKDRWLAKQWTLVSE 465 tropical clawed...
XP_019203550 393 ---EAAQAIFAPMARAMQKYLRTTRQQAFHSMESILTHLQFCITHNMTPKAFLERYLTAGPTMQYQQQNGRGRQWTLVSE 469 Nile tilapia
XP_016159644 394 ---EAAQAIFPSMARALQKYLRTTRQQQYHSMESILQHLAFCITNNMTPKAFLERYLNPGPTLQYDRDRWFSKQWTLVSE 470 collared flycat...
1_pfamImport 364 dslTCLENIVSTITR-IHEYTSTCRQPHRLPLNPVM-RLTDCLLVHSRMELFCESEPEPGPFCS-----------SVXSD 430
XP_007259108 397 ---EAAQAIFPSMARALQKYLRTTRQQHCHSMESIQQHLAFCITHNMTPKAFLESYLMPGPTLQYGRERWLAHQWTLISE 473 Mexican tetra
AAI63391     395 ---EAAQAIFPSMARALQKYLRTTRQQHCHSMDSIQAHLAFCITNNMTPKAFLESYLTAGPTLQYGRESSQTRHWTLVSE 471 zebrafish
XP_011608321 420 ---EAALAVFPSMARALQKYLRTTRRQHCHTMESIQKHLAFCLINNMSPKAFLEAYLSPGPTLQYGPERWMADQWTLVSE 496 torafugu

Q7Q072       533 ELLSRPLSDGCTFQLIQNDVSLTVSIHRIPHFTVSEEVVDPKSNKFVLKLN-SETSV 588 Anopheles gambiae str. PEST
EEN69483     466 LPLHNSLEPGMSFALREQSFSLLVTVMRIPTIKLKEDYQDPKSNKFVLRLQ-SETSV 521 Florida lancelet
CBY14823     489 YPMISSLRPGVVFSIKQADYSLVVTCRTAPKLALREEFVDPASHRFVLRMDsSETSV 545 Oikopleura dioica
Q4VBG5       466 EPVTNGLKDGVVFVLKRQDFSLVVSTKKIPFFKLSEEFVDPKSHKFVMRLQ-SETSV 521 tropical clawed frog
XP_019203550 470 EPVTSALRQGLVFSLRRLDFSLVVTVTPLPFLRLGEEFIDPKSHKFVMRLQ-SETSV 525 Nile tilapia
XP_016159644 471 EAVTSGLQDGVVFVLKCLDFSLVVNVKKIPFIKLSEEFIDPKCHKFVLRLQ-SETSV 526 collared flycatcher
1_pfamImport 431 EAVTNGLRDGLVFVLKCLDFGLVVTVKKIPFIALSEEFVDPKSHKFVLRLQ-SETSV 486
XP_007259108 474 ASVTSGLKEGTVFLLKCIDFSLVVTTKKIPYIKLSEEFIDPKSHKFVLRLQ-SETSV 529 Mexican tetra
AAI63391     472 ASVTSPLRNGSEFQLKSSDFSLVVTSKTIPHLKLSEEYVHPKSHKFVLQLQ-SETSV 527 zebrafish
XP_011608321 497 ASVTSGMKEGTEFLLRCLDFSLAVTVKRIPYIRVTEEFVDPKSHKFLLLLQ-SETSV 552 torafugu