Conserved Protein Domain Family
GATA-N
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pfam05349: GATA-N (this model, PSSM-Id:368398 is obsolete and has been replaced by 461628)
GATA-type transcription activator, N-terminal
GATA transcription factors mediate cell differentiation in a diverse range of tissues. Mutation are often associated with certain congenital human disorders. The six classical vertebrate GATA proteins, GATA-1 to GATA-6, are highly homologous and have two tandem zinc fingers. The classical GATA transcription factors function transcription activators. In lower metazoans GATA proteins carry a single canonical zinc finger. This family represents the N-terminal domain of the family of GATA transcription activators.
Links
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Statistics
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PSSM-Id: 368398
Aligned: 33 rows
Threshold Bit Score: 89.0425
Created: 5-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q61169       147 MYQTLAALSSQGPAAYdgaPGGFVHSaaaaaaaaaAASSPVYVPTTRVGSMLSGLPYLQGAGS--GPSN----------H 214 house mouse
P43692         1 MYQGLALAPNHGQSAYshdSGNFLHS---------SAGSPVYVPTTRVPSVLQTLPYLQSCE---PHQS----------H 58  chicken
XP_007653975   1 MYQSLALAPNHGQSAYshdSTNFLHS---------SASSPVYVPTTRVPSMLQTLPYLQGCES--AHQA----------H 59  platypus
Q9W6U0         1 MYSSLALSSN--PSPYahdSGNYIHP---------SASSPVYVPTTRVPAMLQTLPYLQTCES--SHQA----------H 57  zebrafish
XP_005462816   1 MYQSLAFSSN--QSHYthdTGNYIHP---------SASSPVYVPSTRVPAMLPTLPYLQTCDS--PHQS----------H 57  Nile tilapia
XP_005996700   1 MYPSLALAPNHGQTAYshdSSNFIHS---------STTSPVYVPTTRVPPMLPTLPYLQGCDT--THQS----------H 59  coelacanth
CAF89866       1 MYQSLALSPN--QPPYphdTGTYLHP---------PASSPVYVPSSRVPAVLPTLPYLQPCEA--PPQShglgghhglgG 67  spotted green p...
XP_007250842   1 MYSSLAISSN--PSPYahdSAGYIHP---------SASSPVYMASGRVPAVLQPLSYLQPCEPahAHQT----------H 59  Mexican tetra
XP_015220493   1 MYQSLALAPN--QPPYahdSGNYIHS---------SASSPVYVPTTRVPSMLQTLPYLQTCDS--AHQS----------H 57  spotted gar
XP_003421817   1 MYQSLALALSPNQAAYa-dSGTFLHAp--------GAGSPVFVPPARVSSM---LPYLPACEP--GPQP----------P 56  African savanna...

Q61169       215 AGgaGAHPGWSQASA-DSPPYGGggaagggaagpggagsATAHA-------SARFPYSPSPPM---ANGAARDpGGYvaa 283 house mouse
P43692        59 -Lg--nPPGWAQSSG-ETTAFNA----------------GSPHP-------PSGFSYPHSPRA---AAPRGVD-GAY--- 104 chicken
XP_007653975  60 PLg--nHPGWAQAGG-EASAFNP----------------GSPHP-------PSGFSYSHSPPG---GSNGARD-GAY--- 106 platypus
Q9W6U0        58 GIs--sHHAWPQTGT-DNSSFNP----------------GSPHP-------PPGFSYSHSPPV---SSSTGRD-AAY--- 104 zebrafish
XP_005462816  58 GLt--gHHGWPQAGT-DGSSFTP----------------SSPHP-------SHGFSYSHSPPV---STNTGRD-ATY--- 104 Nile tilapia
XP_005996700  60 PLg--nHPGWAQTGT-ETSAFNQ----------------SSPHTp-------SCFSY--SPPL---SSNTGRE-GAY--- 104 coelacanth
CAF89866      68 HHglGGHHGWPPASA-DGPP--F----------------PPSSPl-----pPHGFSYSHSPPG---SGPSGRE-AGY--- 116 spotted green p...
XP_007250842  60 ALsaHHHHAWPQTAA-DGSAFSP----------------GSPHPa-----hP--------------HSHPHAP-PAF--- 99  Mexican tetra
XP_015220493  58 SLg--sHHGWPQAGT-DTSAFNA----------------GN----------PPGFSYSHSPPV---SGGTVRE-GAY--- 101 spotted gar
XP_003421817  57 ALa--vHPGWAQA-AaDPSAFGA----------------GSPHPppaqppgSAAFPFAHSppgpggggAGGRDgDAY--- 114 African savanna...

Q61169       284 ggtgagsvsgggGSLAAM--GGREhQY----------SslsaARPLNGTYhhhhhhhPtYSPYMAAPLTP-AWPAGPFET 350 house mouse
P43692       105 ------------QGPLLLggGGRe-QYg---------Na--lVRSVNGSYs-----sP-YPAYVTPELPP-SWTAGHFES 153 chicken
XP_007653975 107 ------------QSPLLLgsGGRe-QYg---------Na--lVRSVNGSYp-----sP-YPAYVSPDMAP-SWTTGHFES 155 platypus
Q9W6U0       105 ------------QNPLMLsnGGRAdQYg---------Sa--lVRSVGGSYs-----sP-YAAYMSPEMAT-SWTPGPFDG 154 zebrafish
XP_005462816 105 ------------QSPLVLgnGARAdQYg---------Ga--lVRSVGGSYs-----nP-Y-AYMSPEMATsSWTPGHFES 154 Nile tilapia
XP_005996700 105 ------------QSPLVIsgSGRE-QY----------Gna-lVRSVSGSYs-----sP-YHTYVNPEMPP-SWTTGPFES 153 coelacanth
CAF89866     117 ------------QGALVLgnGARA-DAy--------gGa--lVRTFGGSYs-----sP-Y-AYMSPEMATsSWTPGPFES 166 spotted green p...
XP_007250842 100 ------------SYASSPpaSSAD-QYgpgggtagggGa--lVRSSSYSSp--------yAAYMSPDVT--SWSPGHFDG 154 Mexican tetra
XP_015220493 102 ------------QNPLVIsnGSRAeQYg---------Na--lVRSVNGSYs-----sP-YPTYMSPEMAS-SWSPGHFEG 151 spotted gar
XP_003421817 115 ------------QGALL----GRE-QYp---------Ap--lGRPVGASYp-----gA-YPPYVGPDVTP-TWATGPFDT 159 African savanna...

Q61169       351 PVLHSLQGRaGAPLPVpRGPST 372 house mouse
P43692       154 SVLHSLQTR-QAALPG-RRSTF 173 chicken
XP_007653975 156 TVLHSLQSR-QAALPG-RRSTF 175 platypus
Q9W6U0       155 GMI-GLQGR-QGTLPG-RRSSI 173 zebrafish
XP_005462816 155 GVI-SLQGR-QGGLSG-RRSSL 173 Nile tilapia
XP_005996700 154 TMIHSLQSR-QAALPG-RSSfd 173 coelacanth
CAF89866     167 GV-TSPAGR-PGGPAG-RRASL 185 spotted green pufferfish
XP_007250842 155 SMI-GFQGR-QGALAG-RRSSL 173 Mexican tetra
XP_015220493 152 SMI-SLQSR-QAGLSG-RRSSL 170 spotted gar
XP_003421817 160 SVLPGLQGR-SAGLQG-RPAgl 179 African savanna elephant
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