3WYG


Conserved Protein Domain Family
PKI
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pfam02827: PKI (this model, PSSM-Id:367206 is obsolete and has been replaced by 460716)
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cAMP-dependent protein kinase inhibitor
Members of this family are extremely potent competitive inhibitors of camp-dependent protein kinase activity. These proteins interact with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
Links
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Statistics
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PSSM-Id: 367206
Aligned: 29 rows
Threshold Bit Score: 69.232
Created: 30-Apr-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3WYG_D         2 TDVETTYADFIASGRTGRRNAIHDILVSSASGNL-NELALKLAGLDI---NKTEGEEDAQRSSTEQSGEAQGE 70  human
9_pfamImport   1 TAVNANFDDFLQTGRTGRRNAMPHIMTEGAAVGT-GDLPCEMGKLSC---SDSSSGTGEASGSTQTGSMPANG 69 
O70139         2 MEVESSYSDFISCDRTGRRNAVPDIQGDSEAVSV-RKLAGDMGELAL---EGAEGQAEGSTPDKEASSQPESS 70  house mouse
EFB14134       2 MGVKTSYSISISGDRTGCQNTVLDTQADSETVSM-RKLAKDMDELAL---EGAERQAEAGTPDREASKQSESN 70  giant panda
XP_006639524   2 MEVESAYSDFISCDRTGRRNAVPDIGGEGAKVGT-GELTKDMAQMDL---KAPEEEGTIASQSSQGEVAGSQE 70  spotted gar
XP_005477977   2 MDVETSYSDFINCDRTGRRNAVPDISGEGSVVTStSELTKDMAEMDL---KAAAGGDPGSSPAPEAEGSNSQA 71  Nile tilapia
NP_001025580   2 TDVESTYADFIASGRTGRRNALHDILVSSSSGNT-SELALKLSELDI---SKSEGDENEKENPSDKTPEEKNQ 70  tropical clawed frog
XP_003757771   1 MEVESSYTDFISCDRTGRRNAVPDIQDDSAAVSV-RKLTGNMGELAL---EGAEGQEERSTSDKEAGTTPEGN 69  Tasmanian devil
XP_001515972  27 MEVESSYSDFISCDRTGRRNAVPDIQSGAEAASV-RKLAGDLGELAL---ETAEGQAEASAADKEAGASPEGS 95  platypus
XP_015210495   2 TDVEATYADFIASGRTGRRNALHDILGAQGDLEG-GDLSLKLSELDLgktGEGDGGEKSQASSTERPPSAQEE 73  spotted gar
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