3VI3,3VI3,3V4P,5E6R


Conserved Protein Domain Family
FG-GAP
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pfam01839: FG-GAP (this model, PSSM-Id:366834 is obsolete and has been replaced by 460357)
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FG-GAP repeat
This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N-terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats.
Links
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Statistics
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PSSM-Id: 366834
Aligned: 186 rows
Threshold Bit Score: 29.4251
Created: 30-Apr-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3VI3_A  285 FGYAVAAT-DVNGDGLDDLLVGA---PllmdrT-PDGRPQevGRVYVY 327  human
Q93J50  520 SRVKSVVG-DFDGDGRDDLSVF----------Y-GQGDDT--VKTYVF 553  Streptomyces coelicolor
Q7URB8   50 ANEGIAAG-DVDGDGKTDLVAGR---N-----WfRNGDWAp-RPLRAI 87   Pirellula sp.
O31526  150 SANDASVG-DVDGDGQYELILKWdpsN-----SkDNSQDG--YTGDVL 189  Bacillus subtilis subsp. subtilis str. 168
Q9KDU5  471 TANDASVG-DLDGDGQYEIILKWdptN-----SkDNSRSG--YTGNVY 510  Bacillus halodurans
Q9X8V6  122 AVFEAEAScDLDGDGFTDLVVTTd-pP-----YdGQGRPP--VPLQLL 161  Streptomyces coelicolor
O70362  715 FGSVLHLT-DLDDDGLDEIIMA------------APLRIT--DVTSGL 747  house mouse
Q8CJT9  469 FGAVVGLT-DLGGDGRADLVVT------------APGSDTveGVAYLL 503  Streptomyces coelicolor
P73139 2087 SGLNTDFT-DYDGDGRQDLVIA------------GPGANT--NTGQAF 2119 Synechocystis sp. PCC 6803
O31527  328 GNHSLSVA-DVDGDGKDEIIYG----------A-MAVDHD--GTGLYS 361  Bacillus subtilis subsp. subtilis str. 168
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