Conserved Protein Domain Family
BTB_POZ_KLHL41_KBTBD10

?
cd18341: BTB_POZ_KLHL41_KBTBD10 
BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 41 (KLHL41)
KLHL41 is also called Kel-like protein 23, Kelch repeat and BTB domain-containing protein 10 (KBTBD10), Kelch-related protein 1 (Krp1), or sarcosine. It is a novel kelch-related protein that is involved in pseudopod elongation in transformed cells. It is also involved in skeletal muscle development and differentiation. It regulates proliferation and differentiation of myoblasts and plays a role in myofibril assembly by promoting lateral fusion of adjacent thin fibrils into mature, wide myofibrils. It contains a BTB domain and kelch repeats, characteristics of a kelch family protein. The BTB/POZ domain is a common protein-protein interaction motif of about 100 amino acids.
Statistics
?
PSSM-Id: 349650
Aligned: 6 rows
Threshold Bit Score: 243.985
Created: 13-Sep-2017
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
14285509       6 ELAEELRLYQSTLLQDGLKDLLDEKKFIDCTLKAGDKSLPCHRLILSACSPYFREYFLSEi--dEAKKKEVVLDNVDPAI 83  human
OCA23669       6 EIKDELRLYQSTLLQDGLKELLDENKFVDCFLKAGSKSLPCHRLILAACSPYFREFFLSDe--sEEKKKNMELDNVEPST 83  western clawed ...
F1QEG2         5 AIKEELRLFQSTLLQDGLKELLNENKFVDCTLKIGDRCFPCHRLIMAACSPYFRELFFSEdgkeKDIGKEVVLDDVDPNI 84  zebrafish
XP_007888172   6 DIREESRLYQTTLLQDGLKELLDENKFVDCSLKIGTKAFPCHRLILAACSPYFREYFFSEen-tEEKKKEVVLEDVDPNV 84  elephant shark
KFW86865       6 ELTEELRLYQSTLLQDGLKELLEEKKFIDCSLKAGDRSLPCHRLILSACSPYFREYFLSEq--sEEKKKEVVLDNVDPNI 83  golden-collared...
AAH43951      30 EMKDELRLYQSTLLQDGLKELLDENKFVDCFLKAGDKSLPCHRLILAACSPYFREFFLSDe--aEEKKKNVELDNVDPST 107 African clawed ...
14285509      84 LDLIIKYLYSASIDLNDGNVQDIFALASRFQIPSVFTVCVSYLQKRLAPGNCLAI 138 human
OCA23669      84 MEAILKYLYSADIDLNDGNVQDIFALASRFQIPSVFTVCVTYLQRRLSPANCLAI 138 western clawed frog
F1QEG2        85 MDMILQYLYSAEIDLVDDNVQEIFAVANRFQIPSVFTVCVNYLQQKLSMANCLAV 139 zebrafish
XP_007888172  85 MDLILKYLYTSEIILNDENVQHIFAVASRFQIPSVFTMCVTYLQKRLAVNNCLAI 139 elephant shark
KFW86865      84 LDMIVKYLYSASIDLNDSNVQDIFALASRFQIPSVFTVCVSYLQKRLAVGNCLAI 138 golden-collared manakin
AAH43951     108 MEAILKYLYSADIDLNDSNVQDIFALASRYQIPSVFTVCVTYLQRRLSPSNCLAI 162 African clawed frog
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap