Conserved Protein Domain Family
BTB_POZ_KLHL26
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cd18255: BTB_POZ_KLHL26 
BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 26 (KLHL26)
KLHL26 is encoded by the klhl26 gene, which is regulated by p53 via fuzzy tandem repeats. It contains a BTB domain and kelch repeats, characteristics of a kelch family protein. The BTB/POZ domain is a common protein-protein interaction motif of about 100 amino acids.
Links
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Statistics
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PSSM-Id: 349564
Aligned: 13 rows
Threshold Bit Score: 216.492
Created: 13-Sep-2017
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q53HC5        45 HSTSLLQGLATLRAQGQLLDVVLTINREAFPAHKVVLAACSDYFRAMFTGGMREASQDVIELKGVSARGLRHIIDFAYSA 124 human
XP_006003982 145 HSTTLLQGLAALRAQGQLLDVILTVNDETFKVHKVVLAACSDYFRAMFTGGMKESNQDVIELKGVSAKGLKHIIDFAYSA 224 coelacanth
XP_018111753  33 HSTTLLQGLTALRAQGQLLDVILTINNEVFQVHKVVLAACSDYFRAMFTGGMRESNQDVIELKGVSSRGLRHIIDFAYSA 112 African clawed ...
XP_007897105  17 HSAALLRGLAALRAQGQLLDVVLMVNNEPFPVHKATLAACSDYFRAMFTGGMREASQDVIELKGLSAKGLKRIVDFAYSA 96  elephant shark
Q5RGB8        35 HSSTLLRGLSALRDQGQLLDVVLAIDNERFEVHKAVLASCSDYFRAMFTGGMKESNQNTIELIGLSARGLKHIIDFAYSS 114 zebrafish
XP_007430389  17 HSVTLLHGLASLRAQAQLLDVILTINNEVFQVHKVVLAACSDYFRAMFTGGMRESNQDVIELKGVSAKGLKHIIEFAYSA 96  Burmese python
XP_002592848  15 HSDSLLRGLNALRSDSLLCDVTLVADDQGFQAHRAVLASCSDYFKAMFTSGMRESSETHVELKGVSANGLQHVLDFAYTS 94  Florida lancelet
EKC35147      43 HGDSVLAGLKYLREKQQLFDVTFIVEGQKFQAHRVVLASCSDYFRAMFTDGLVECQKDIISLNGVTAKGMKNLIDFAYSS 122 Pacific oyster
ELT88493      19 HSASVLTGLNALREKDQLFDVTLVADGQSFGAHRVALAASSDYFRAMFTDAMLECKQTQIELNGVGALGLKHILDYAYTS 98  Capitella teleta
XP_013779905  25 HVGTLLGGLNSLRSKGLLLDITLIADGQSFKAHRVVLASCSDYFRAMFTDAMKESKLSEISLNGVSAEGMKYVLDYVYTS 104 Atlantic horses...
XP_021930225  24 HTTTLLCGLNALRTKGLLLDVTLVADGEAFQAHRVVLASCSDYFRAMFTDAMRESRQSEICLNGVTAAGIRLLLDYAYTS 103 Zootermopsis ne...
PAA55771      70 HAVMVLQGLCSLRSKSVLTDVTLLADGQRFDVHKVILVSCSDYFRSMFTSGMKECSQSEIELKGVTAKGLEKVLDIIYTS 149 Macrostomum lig...
XP_013394379  33 HGVKILQGLNHLKRDKVLCDVTLIAEAQRFDVHKVILVSCSDYFRSMFTSGMKESTQREIELKGVTARGLDKVLEIVYTS 112 Lingula anatina

Q53HC5       125 EVTLDLDCVQDVLGAAVFLQMLPVVELCEEFLKAAMSVETC 165 human
XP_006003982 225 EVALDLDCIQDVLGAAVFFQMVPVVELCEEFLKSAMSVETC 265 coelacanth
XP_018111753 113 EVTLDLDCIHDVLGAAVFLQMVPVVELCEEFLKSAMSVETC 153 African clawed frog
XP_007897105  97 EVTLDLDCIQDVLGAAVFLQMEPVVELCQEFLKSAMSVETC 137 elephant shark
Q5RGB8       115 EVTLDLDCIQDVLGAAVFLQMVPVVELCEEFLKSAMSVETC 155 zebrafish
XP_007430389  97 EVTLDLDCIQDVLGAAVFLQMVPVVELCEEFLKSAMSVETC 137 Burmese python
XP_002592848  95 RLGLSLQIVQDVIGAASHLQVLPIIVIVEKFLVAEINVDNC 135 Florida lancelet
EKC35147     123 KLFLDFDNVEDILLSANHVQMLPVLQACSDFLQQHLSIENC 163 Pacific oyster
ELT88493      99 KLTLTLGNIQDILRAASHLQLLPVVSACASYLHLQLDLDNC 139 Capitella teleta
XP_013779905 105 RLALSLANIQDVLSAASHLQLLAVVEACSSYLQKQLDIENC 145 Atlantic horseshoe crab
XP_021930225 104 RLALNLANIQDVLSAANHVQVVAVVEACSSYLQAQLDLENC 144 Zootermopsis nevadensis
PAA55771     150 STSIEGDDVFDILAAATHLQVMPVLEFCERNFLRNMTAANF 190 Macrostomum lignano
XP_013394379 113 STTLDGDDIFDVTAAATHLQVTPVIEFCEKNFLSGMTTGNF 153 Lingula anatina
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