Conserved Protein Domain Family
zf-SNAP50_C
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pfam12251: zf-SNAP50_C (this model, PSSM-Id:338291 is obsolete and has been replaced by 463506)
snRNA-activating protein of 50kDa MW C terminal
This domain family is found in eukaryotes, and is typically between 196 and 207 amino acids in length. There is a conserved CEH sequence motif. SNAP50 is part of the snRNA-activating protein complex which activates RNA polymerases II and III. There is a cysteine-histidine cluster which contains two possible zinc finger motifs.
Links
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Statistics
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PSSM-Id: 338291
Aligned: 66 rows
Threshold Bit Score: 174.304
Created: 28-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q555K3        813 MDILVLGSHKLTVLRDKIYCLS---D----------------C----------------ILDG--S-----NRKSGFFFI 850  Dictyostelium...
Q8IKM4        440 AEYEILSNQTLANLTDVFFCFD---T----------------S----------------NYGL--P-----KCDGSLYFI 477  Plasmodium fa...
Q4Y8Q3        402 AEFEILSTQTLANLTDVFFCFD---T----------------S----------------NYGM--P-----KFSGSVYYI 439  Plasmodium ch...
OAJ45188      184 ASVKILGGQTLADLRDVLLCSS---D----------------L----------------ILIG--NeaqntQTRPGYFFI 226  Batrachochytr...
OII75828      214 AEFDVLEYQTLAEIRDAFNCDDskrE----------------E----------------ELLK--V-----KTKGACFFI 254  Cryptosporidi...
XP_001945758  165 kTLQFYDTQTLHDLKQGFKCEN---E----------------EseisgdisknphkpleFIVN--S-----DLKHGLFYI 218  pea aphid
XP_001612189  305 rEFDMLSSQTLAELRDAFRCAS---E----------------I----------------RPLNvdL-----KANGSCFML 344  Babesia bovis...
XP_001388372  249 SEFDILETQTLSELSNSFICHD---Skq-------------eE----------------ELLG--F-----HPTGDCFEI 289  Cryptosporidi...
KMZ98112      400 AEYEILSSQTLADLTDVFFCFD---S----------------S----------------NYGL--P-----QFEGSVYYI 437  Plasmodium vi...
XP_016663495  145 ntIQFYDTQTLQDLKQVFKCKN---EeseisgdvsnnihkplE----------------FIEN--S-----DLKHGSFYI 198  pea aphid

Q555K3        851 NNVFYND-NRD--QR--NYQYSKNTLAWLKERGKDI-S--N-------------FKEESMDDVTFNDLEISIGERYLYCH 909  Dictyostelium...
Q8IKM4        478 DGILYPD-LRS--NN--AVDYSTSILNFYKMKkmktnfik-------------ypykinqDKAILSQIEIPLFKKCCFLH 539  Plasmodium fa...
Q4Y8Q3        440 DGILYPD-VRD--KD--ALDYSTSIINFYKNRknissstassssnsnlddflkhpykiyqDKAVLKDIKIPLYKKCCFLH 514  Plasmodium ch...
OAJ45188      227 ENTFYVD-LRD---N--AVDCSRVIRSWMELDKESF-GntE-------------IKAARMDETKLWQLSIELNQAYLYMH 286  Batrachochytr...
OII75828      255 DGVLYPD-LREteDG--IINYATYLKGYCNTVNTIG-N--K-------------EEIIPMHKRKLNEISIPINLPCSFLH 315  Cryptosporidi...
XP_001945758  219 NNNLYVDsLPD--RS--TLMHAETMKSWASCNGHTI------------------QNILSM-DTQLLDLEVCIGQPYVYQH 275  pea aphid
XP_001612189  345 NGQLFPD-LRN--D---ACDYSEPLLHFLYNYKPGIlR--T-------------SECIEQTDAVLSHLELPIYMPGFLLH 403  Babesia bovis...
XP_001388372  290 NGDLY---LNG--TDdiKSNFINTLSGFTMKSnp---------------------qIFDMKNTQISHLNIPINSHSTYIH 343  Cryptosporidi...
KMZ98112      438 DGVLYPD-LRS--PS--ALDYSACILEFYKKKkesnfir--------------ppykvlqHKAVIGQMEIPLYQRCCFLH 498  Plasmodium vi...
XP_016663495  199 NNNIYVD-SSL--V---SMEYTETMKKWACDHght------------------idnILSI-DTQLLDLEVCIGQPYVYQH 253  pea aphid

Q555K3        910 QGSCEHLVTFESLRMVN-E-M-DDLEPSRYPIITYQQKVRRRKCLVCDIYAAKYVTLG-DQFADETPFFYCDECYRTFHY 985  Dictyostelium...
Q8IKM4        540 QGTCEHRIVFNNIRQYNkL-R-D-KHLSKYPLRTFKPNISNKYCISCHKNIAQKIVLD-SYLLKENPSYMCNNCFDLFLM 615  Plasmodium fa...
Q4Y8Q3        515 QGNCEHRIVFSNVRQYNkF-R-D-KDISQYPIRTFKPNIATKYCICCHKNIAQKIIID-SYLFKENPSYVCDGCFELFLL 590  Plasmodium ch...
OAJ45188      287 QGSCGHLMTFDQIGLFN-P-NvDSKYRKDYPISTPITNICMPKCHVCGVFYAKYATVD-DLHTAETPSIWCLDCFNQFHL 363  Batrachochytr...
OII75828      316 SGDCEHRFTFTNIRVYQ-EcV-DCPYEDVYPLQIYSPSTILTFCEICGINLANKLIFN-ALNLPKNPSYLCDSCTFAFLY 392  Cryptosporidi...
XP_001945758  276 LGRCEHLFIFNEINIAK-S-N-DCLGQTNYPRVISVAKEKLKNCIFCYKNIASIVMLNdDERTPLTVNHMCESCFKSYNY 352  pea aphid
XP_001612189  404 HGDCEHRLMITAIRIFD-RtR-DCPYEECYPLKVFMPRQRAKQCNVCEYNEPSTTVFN-SLVLPHIPSHLCNYCYTRLkl 480  Babesia bovis...
XP_001388372  344 SGDCEHRVTFTNIRLFNsK-Y-DSPYKDSYPIQIYSHSRTLTFCEICGINQVTKVIFN-SLNLPRNPSQLCDSCTFIFLY 420  Cryptosporidi...
KMZ98112      499 QGNCEHRIIFNNIRQYNsL-R-D-GESSKYPLRTFKPNIAKKLCLCCRKNMAQRIVLD-CYLFKENPSYVCNCCFDLFLL 574  Plasmodium vi...
XP_016663495  254 LGRCEHLFIFNEINIAK-F-N-DWLIQSKYPRVVSVEKEKLQKCIFCRKTVATIVMLSeNDRTLQTVNHMCKHCFESYNY 330  pea aphid

Q555K3        986 sKDG-HLLySNYQVFP 1000 Dictyostelium discoideum AX4
Q8IKM4        616 dKNN-QPIdTSMKYFD 630  Plasmodium falciparum 3D7
Q4Y8Q3        591 dSNG-KPVdDMMKHFQ 605  Plasmodium chabaudi
OAJ45188      364 nPSG-QPrynvqlrei 378  Batrachochytrium dendrobatidis JEL423
OII75828      393 dKETrNPL-ENFiicn 407  Cryptosporidium andersoni
XP_001945758  353 dHLD-DKV-SDFKAYR 366  pea aphid
XP_001612189  481 lessggvyrsdglass 496  Babesia bovis T2Bo
XP_001388372  421 dKNT-K---QSIEKCI 432  Cryptosporidium parvum Iowa II
KMZ98112      575 dRQG-HPVdALMKHFA 589  Plasmodium vivax North Korean
XP_016663495  331 dDFG-NKI-SNFKc-- 342  pea aphid
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