3TX3


Conserved Protein Domain Family
EI24
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pfam07264: EI24 (this model, PSSM-Id:336651 is obsolete and has been replaced by 462129)
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Etoposide-induced protein 2.4 (EI24)
This family contains a number of eukaryotic etoposide-induced 2.4 (EI24) proteins approximately 350 residues long as well as bacterial CysZ proteins (formerly known as DUF540). In cells treated with the cytotoxic drug etoposide, EI24 is induced by p53. It has been suggested to play an important role in negative cell growth control.
Links
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Statistics
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PSSM-Id: 336651
Aligned: 311 rows
Threshold Bit Score: 30.5983
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3TX3_A        16 YIGRGLELIRTKGLRRYVVVPILTNLI------------------------------------------------LFsla 47  Idiomarina loih...
Q7VTW0        26 AFKRALVSQCHPNMLFAVLLPFLIALLgailllwlfwtplnewlrfeasqwqainqvddwmvaaglfslkiylvpVI--- 102 Bordetella pert...
WP_023596346   7 ALGRALVSLLHPRMLWLTAMPFVVSGLiwgaviwfgwepftdflrvwleqweftqwiyrffgffgvdsvrmalapFI--- 83  Pandoraea pnome...
WP_011903096  10 SFGLALVGTMHPRMLWLSLRPFLIVSIlwgcliwltwtpalemlsifltnsiftswiqdgliwagfenarawiapLF--- 86  Polynucleobacte...
WP_013233651   7 sfgRALLAQLHIRMLWLTVLPFVVSLAlwalclwlglqpvidwlqdyfvshgmfgeiggmlawfgmgalktvlvpLL--- 83  Herbaspirillum ...
WP_011870341   7 aFGRALLSQLHIRMLLLSVLPFVLSIAvwgivlwlylqsmidtlqnyfvendgfrvtnemllwlgmgalktvvvpLI--- 83  Herminiimonas a...
WP_025371739  24 AFGRALVSQLQPRMLLALLLPFAAALIamlffarflwgpvadwlnlfvtqsemmtdmeswmagvglfsltvyvvhIL--- 100 Advenella mimig...
WP_052355886  23 AFRRAAASQLHPRMIAALFLPFVIAFLgavvllwffwqpltgwldqeasswglfntidgwlvavglfslklwlvpLL--- 99  Castellaniella ...
WP_013743061  23 AFKRALVSQCHPKMLLALFLPFLIALLgaiillwafwdpltswlnmqasewgfinqldqwmlaiglfsiklylvpLL--- 99  Pusillimonas sp...
WP_014752281  12 aFSKAIATQMRPSMLLAVILPFVIALItavillvfawgpldnwldntamhwgwfqsvstrlsgwgfvtmsdwltgVL--- 88  Advenella kashm...

3TX3_A        48 ftwlygevdywlnrfmswlpdffqwlefilwplavitIIALFSFIFSTIMHLIAAPF-NGLLAEKVERyE---------- 116 Idiomarina loih...
Q7VTW0       103 -------------------------------------AAAILLPISGILGLAIAAVFvMPLVLRHVGGrEyaglarqg-r 144 Bordetella pert...
WP_023596346  84 -------------------------------------LVALLVPLIVVTSLLLIAGWsMPAVLRHLSRrHfihlearq-g 125 Pandoraea pnome...
WP_011903096  87 -------------------------------------FVMLIIPLITISLLVFIAFTtVPAIVNIVARqAgyqgleikrg 129 Polynucleobacte...
WP_013233651  84 -------------------------------------AMWTLLPLMIITALVFVGLFtIPAIARHIGArHypmlekry-g 125 Herbaspirillum ...
WP_011870341  84 -------------------------------------AMWILLPLMILTALIFVGMMaMPVIAKHVGSrQyqeletrk-g 125 Herminiimonas a...
WP_025371739 101 -------------------------------------VFVIMVTLGSSIGLLIAAVLvMPMVVGHVARtDypeldrrg-r 142 Advenella mimig...
WP_052355886 100 -------------------------------------AAGLLLPMAGILGLVIAAVFvMPIVLRHLEHrEyrglnrqg-r 141 Castellaniella ...
WP_013743061 100 -------------------------------------AVGILLPISGILGLIIAAVFvMPIVLRHLEKgEyqgvlrqg-r 141 Pusillimonas sp...
WP_014752281  89 -------------------------------------TFVALLAVSGIAGLAAAAILvMPMALKVIGDgSypdvqkkg-e 130 Advenella kashm...

3TX3_A       117 -------SgeslgdegflglfkdipRTLKremqKLMYYIPRALGFFLL-SlvIPvIGQ----VLWYIFVCWmMSIQYLDY 184 Idiomarina loih...
Q7VTW0       145 natavsvW-----------------NALW----VSLAFGAGWLLTLPFwL--IPpMVVilsvFWWAFAFTRmLRLDAIVE 201 Bordetella pert...
WP_023596346 126 gsfwgslG-----------------QSLG----ATLIFLVAALVTLPLwL--VPpFFAivppLLWGWLTYRvMTYDALAY 182 Pandoraea pnome...
WP_011903096 130 ggfwgslV-----------------YTLW----SALLCLVLVILTLPVwW--LPpLVAvlppLLWGWLTMRlMSYDVLAK 186 Polynucleobacte...
WP_013233651 126 gsvagslW-----------------TSLW----CFAVFTVLWISTIWVfL--IPpLALvihsLLWGWLTYRvMAYDTLAD 182 Herbaspirillum ...
WP_011870341 126 gtffgslW-----------------MSTS----SFTIFLVLWLVTLPLsL--IPpLTFviqpLLWGWLTYRvMAYDALAD 182 Herminiimonas a...
WP_025371739 143 qvfvssmV-----------------NSIK----VVLVFIAGWVITLPLwL--IPpVAVllhvFWWAYAFTHmLRFDALVE 199 Advenella mimig...
WP_052355886 142 nttalgvW-----------------NAIW----VGLLFCLGWLVTMPLwL--IPpMALvlpvFWWAFALNRmLRVDAMIE 198 Castellaniella ...
WP_013743061 142 ystavgaW-----------------NAIW----VGCIFAIGWLVTMPLwL--IPpFAVllplFWWSFAFTRmLRVDATIE 198 Pusillimonas sp...
WP_014752281 131 natvtslA-----------------NTVK----VSTIFVVGWLITLPLwL--IPfAGIalslFWGAYAFSHmTRLDAIVE 187 Advenella kashm...

3TX3_A       185 PFdnhklSFPRMRSELHQQRSKTLGFGFGVTVLTMIPLINLII 227 Idiomarina loihiensis
Q7VTW0       202 HA-----SPAERAILLKRHNSGFWLIGLVCSLLNLLPPAWIIL 239 Bordetella pertussis
WP_023596346 183 HA-----TAEERRRIVREKRLPLLVIGVATGLLGSLPTLLWVS 220 Pandoraea pnomenusa
WP_011903096 187 HA-----SSQERDLLLEKYRWPLLCMGIASGMLGAVPTFFWAT 224 Polynucleobacter necessarius subsp. asymbioticus
WP_013233651 183 YA-----SAEERRAVLHLHRWPLLAVGTVAGALGAAPTLLWLG 220 Herbaspirillum seropedicae
WP_011870341 183 HA-----DPEERKLILRMHRWQLLAIGAITGAMGAAPTLLWLG 220 Herminiimonas arsenicoxydans
WP_025371739 200 HA-----TEQERAQVIARRRGGGWLIGTICAILNLIPLTWIVL 237 Advenella mimigardefordensis
WP_052355886 199 HA-----SAAERRLLWRRHNRQLWLIAACLAVVNLIPLFWLVM 236 Castellaniella defragrans
WP_013743061 199 HA-----SAQERRLLWRQHNRQWWLIGCILALINLFPPAWLFL 236 Pusillimonas sp. T7-7
WP_014752281 188 HA-----TLEERAYVLRHYSRGFWLIGLICAAIALIPFAGFVM 225 Advenella kashmirensis
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